Cristiana Voineag, G. Radulian, Bianca Demetra Postolache, Nicolae Popescu
In Romanian specialized literature, there is no national/regional registry that highlights the number of people with diabetes as well as the micro and macrovascular complications that affect the quality of life and lead to high economic costs. In this sense, the purpose of this study was to create a database to highlight essential variables according to demographic aspects, anthropometric indicators, glycosylated hemoglobin, chronic complications secondary to diabetes in order to define a profile of the diabetic patient and in the implementation of a early management algorithm in Braila County Hospital.
{"title":"Evaluation of metabolic control and chronic complications in a cohort of patients admitted to Braila County Emergency Hospital","authors":"Cristiana Voineag, G. Radulian, Bianca Demetra Postolache, Nicolae Popescu","doi":"10.37897/rmj.2023.1.2","DOIUrl":"https://doi.org/10.37897/rmj.2023.1.2","url":null,"abstract":"In Romanian specialized literature, there is no national/regional registry that highlights the number of people with diabetes as well as the micro and macrovascular complications that affect the quality of life and lead to high economic costs. In this sense, the purpose of this study was to create a database to highlight essential variables according to demographic aspects, anthropometric indicators, glycosylated hemoglobin, chronic complications secondary to diabetes in order to define a profile of the diabetic patient and in the implementation of a early management algorithm in Braila County Hospital.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90095099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Cahyanur, A. Kosasih, L. Widjaja, Marini Stephanie, A. Harahap, Harits Adi Putra
Objectives. We present an extremely rare case of breast cancer with metastasis to the bone marrow, which was also simultaneously diagnosed with chronic lymphocytic leukemia (CLL). Case Presentation. A 56-year-old female with a history of routine blood transfusions presented with chronic fatigue and recurrent right upper quadrant abdominal pain due to cholecystitis. Additionally, nodules were palpable in both breasts, which were subsequently detected as suspicious calcified lesions on ultrasound. Leukocytosis and bi-cytopenia were found. Cholecystectomy was performed and biopsies from some tissues were conducted. Gall bladder and subcutaneous tissue from the umbilical area showed neoplastic cells suggestive of breast carcinoma. Bone marrow biopsy showed CLL and non-hematopoietic cells identical to the previously detected neoplastic cells. Immunohistochemistry revealed that the breast carcinoma was ER-positive, PR-positive, and HER2negative. Outcome. After a thorough investigation, the bone marrow depression was proven to result from a metastatic bone marrow lesion from breast cancer diagnosed concurrently with CLL. Conclusions. This circumstance obliged clinicians to be more considerate of the diagnostic approach and treatment of patients with neoplasm presenting with cytopenia. It is to avoid underdiagnosis and ensure that every pathology in the bone marrow is investigated and managed accordingly.
{"title":"Bone marrow metastasis of breast cancer and chronic lymphocytic leukemia: A coincidence","authors":"R. Cahyanur, A. Kosasih, L. Widjaja, Marini Stephanie, A. Harahap, Harits Adi Putra","doi":"10.37897/rmj.2023.1.5","DOIUrl":"https://doi.org/10.37897/rmj.2023.1.5","url":null,"abstract":"Objectives. We present an extremely rare case of breast cancer with metastasis to the bone marrow, which was also simultaneously diagnosed with chronic lymphocytic leukemia (CLL). Case Presentation. A 56-year-old female with a history of routine blood transfusions presented with chronic fatigue and recurrent right upper quadrant abdominal pain due to cholecystitis. Additionally, nodules were palpable in both breasts, which were subsequently detected as suspicious calcified lesions on ultrasound. Leukocytosis and bi-cytopenia were found. Cholecystectomy was performed and biopsies from some tissues were conducted. Gall bladder and subcutaneous tissue from the umbilical area showed neoplastic cells suggestive of breast carcinoma. Bone marrow biopsy showed CLL and non-hematopoietic cells identical to the previously detected neoplastic cells. Immunohistochemistry revealed that the breast carcinoma was ER-positive, PR-positive, and HER2negative. Outcome. After a thorough investigation, the bone marrow depression was proven to result from a metastatic bone marrow lesion from breast cancer diagnosed concurrently with CLL. Conclusions. This circumstance obliged clinicians to be more considerate of the diagnostic approach and treatment of patients with neoplasm presenting with cytopenia. It is to avoid underdiagnosis and ensure that every pathology in the bone marrow is investigated and managed accordingly.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84051002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Burn injuries have a long-term negative impact on patients, families, and healthcare systems, and prevention remains the primary goal. Head and neck lesions have a reported prevalence between 6-65.6%, sometimes even 95.1%. There are various risk factors and predictors of facial burns, like younger age, male sex, flame or flash burns, and work-related injuries. Surgical and non-surgical management is chosen depending on the burn type and extension, and the patients’ previous health status. Tangential necrosectomy is the gold standard of third-degree burn care. In the last years, enzymatic debridement showed promising results. Long-term complications, from altered sensibility, and face motor dysfunction, to hypertrophic scarring and mutilating aspects, frequently lead to depression, post-traumatic stress disorders, and social exclusion. To improve patients’ quality of life, various programs targeting reconstructive surgeries with cosmetic purposes, social skill training, and cognitive behavioural therapies should be implemented.
{"title":"Burns of the head and neck – from physiological to psychological impact","authors":"M. Tiglis, Ș. Popescu, T. Neagu, I. Lascar","doi":"10.37897/rmj.2022.4.5","DOIUrl":"https://doi.org/10.37897/rmj.2022.4.5","url":null,"abstract":"Burn injuries have a long-term negative impact on patients, families, and healthcare systems, and prevention remains the primary goal. Head and neck lesions have a reported prevalence between 6-65.6%, sometimes even 95.1%. There are various risk factors and predictors of facial burns, like younger age, male sex, flame or flash burns, and work-related injuries. Surgical and non-surgical management is chosen depending on the burn type and extension, and the patients’ previous health status. Tangential necrosectomy is the gold standard of third-degree burn care. In the last years, enzymatic debridement showed promising results. Long-term complications, from altered sensibility, and face motor dysfunction, to hypertrophic scarring and mutilating aspects, frequently lead to depression, post-traumatic stress disorders, and social exclusion. To improve patients’ quality of life, various programs targeting reconstructive surgeries with cosmetic purposes, social skill training, and cognitive behavioural therapies should be implemented.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82151170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Bălescu, Nicoale Bacalbasa, I. Brezean, C. Stoica, C. Tomescu, Cristina Martac, Andrei Voichitoiu, B. Gaspar
The presence of an increased number of platelets has been demonstrated to be significantly associated with the presence of different types of malignancies, especially when it comes to gynecological cancers and seems to be associated with a poorer prognosis. This fact has been widely studied in order to better understand the physiopathology of the phenomenon, the impact on the overall outcomes and to validate new therapeutic lines for such cases. The aim of the current paper is to review the most important studies conducted on this issue.
{"title":"The significance of preoperative thrombocytosis in ovarian cancer patients","authors":"I. Bălescu, Nicoale Bacalbasa, I. Brezean, C. Stoica, C. Tomescu, Cristina Martac, Andrei Voichitoiu, B. Gaspar","doi":"10.37897/rmj.2022.4.7","DOIUrl":"https://doi.org/10.37897/rmj.2022.4.7","url":null,"abstract":"The presence of an increased number of platelets has been demonstrated to be significantly associated with the presence of different types of malignancies, especially when it comes to gynecological cancers and seems to be associated with a poorer prognosis. This fact has been widely studied in order to better understand the physiopathology of the phenomenon, the impact on the overall outcomes and to validate new therapeutic lines for such cases. The aim of the current paper is to review the most important studies conducted on this issue.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"191 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76225913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diana Iulia Vasilescu, A. Dan, Vlad Dima, M. Cirstoiu
Transient neonatal myasthenia gravis (TNMG) is a distinct type of myasthenia gravis (MG), a temporary autoimmune condition due to the mother’s antibodies crossing over the placenta and affecting the baby. Studies suggest that 10 to 15% of infants born to mothers suffering from MG will develop TNMG. Undoubtedly, if not diagnosed and treated in time, TNMG can be a serious condition, even life-threatening. Almost 80% of newborns will present symptoms in the first 24 hours of life that will last up to 4 weeks and a complete recovery is expected by 2 months of age. Only 10% of the affected infants may still be symptomatic at 4 months.
{"title":"Transient neonatal myasthenia gravis: case report","authors":"Diana Iulia Vasilescu, A. Dan, Vlad Dima, M. Cirstoiu","doi":"10.37897/rmj.2022.4.3","DOIUrl":"https://doi.org/10.37897/rmj.2022.4.3","url":null,"abstract":"Transient neonatal myasthenia gravis (TNMG) is a distinct type of myasthenia gravis (MG), a temporary autoimmune condition due to the mother’s antibodies crossing over the placenta and affecting the baby. Studies suggest that 10 to 15% of infants born to mothers suffering from MG will develop TNMG. Undoubtedly, if not diagnosed and treated in time, TNMG can be a serious condition, even life-threatening. Almost 80% of newborns will present symptoms in the first 24 hours of life that will last up to 4 weeks and a complete recovery is expected by 2 months of age. Only 10% of the affected infants may still be symptomatic at 4 months.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"124 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74661419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Neagu, Eliza Bordeanu-Diaconescu, M. Tiglis, I. Peride, I. Lascar
Introduction. Bromelain-based enzymatic debridement may be considered the standard in patients with upper extremity burns management, regarding the low risk of bleeding, wound infections, reduction of surgical timing, and the decreased risk of compartment syndrome development. Case presentation. We present the case of hand and face burns in a patient presenting deep venous thrombosis of the lower limb extended to the level of the vena cava, and bilateral pulmonary embolism. The enzymatic debridement reduced periprocedural bleeding and allowed a faster recovery and therefore the resumption of oral anticoagulation and antiplatelet medication in a patient with important cardiac, arterial, and renal comorbidities. Conclusion. Bromelain-based enzymatic debridement use is recommended in patients presenting upper limb deep burns, especially in anatomically challenging areas, like hand fingers, and especially in those with a previous medical history that predisposes them to periprocedural bleeding and increased risk of poor healing.
{"title":"Bromelain-based enzymatic debridement in hand burns – an easier way to manage a difficult patient: case report","authors":"T. Neagu, Eliza Bordeanu-Diaconescu, M. Tiglis, I. Peride, I. Lascar","doi":"10.37897/rmj.2022.4.4","DOIUrl":"https://doi.org/10.37897/rmj.2022.4.4","url":null,"abstract":"Introduction. Bromelain-based enzymatic debridement may be considered the standard in patients with upper extremity burns management, regarding the low risk of bleeding, wound infections, reduction of surgical timing, and the decreased risk of compartment syndrome development. Case presentation. We present the case of hand and face burns in a patient presenting deep venous thrombosis of the lower limb extended to the level of the vena cava, and bilateral pulmonary embolism. The enzymatic debridement reduced periprocedural bleeding and allowed a faster recovery and therefore the resumption of oral anticoagulation and antiplatelet medication in a patient with important cardiac, arterial, and renal comorbidities. Conclusion. Bromelain-based enzymatic debridement use is recommended in patients presenting upper limb deep burns, especially in anatomically challenging areas, like hand fingers, and especially in those with a previous medical history that predisposes them to periprocedural bleeding and increased risk of poor healing.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81926490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alirio Rodrigo Bastidas Goyes, Sayuris Henríquez Ortiz, Edward J. Acero Mondragon, Estefanía Collazos Bahamon, B. Mantilla, Eduardo Tuta Quintero, G.A. Hincapie Diaz, Elías Quintero Muñoz, David Acosta Hernández, Camila Martínez Ayala
Introduction. Sleep apnea syndrome (SAS) can accompany patients with chronic primary headache (CPH), being a frequent cause of persistence of symptoms in these patients, however, the data studying this disorder in patients with CPH are still limited. Objective. To determine the frequency of SAS in patients with CPH. Methods. A retrospective cohort was analyzed in patients with a diagnosis of CPH in a third level hospital. CPH was diagnosed according to the criteria of the International Headache Society and SAS with a polysomnographic record with an apnea-hypopnea index (AHI) >5/h, the frequency of SAS was determined among the total number of patients with AHI >5/h over the total number of patients undergoing polysomnography. Results. A total of 114 subjects were included, where the SAS in CPH was 83.3%, of which 56.8% were men and 60% older than 50 years; 89% of the population had a body mass index (BMI) greater than 27 kg/m2. Fatigue and sleepiness during the day were the most frequent symptoms, reported in 89.5% of the population with SAS compared to 47.4% of the population without a diagnosis of SAS. Conclusion. Sleep apnea is a frequent condition in patients with CPH undergoing polysomnography, mainly overweight men over 50 years of age. The main associated symptoms are fatigue and sleepiness.
{"title":"Sleep apnea in patients with primary chronic headache","authors":"Alirio Rodrigo Bastidas Goyes, Sayuris Henríquez Ortiz, Edward J. Acero Mondragon, Estefanía Collazos Bahamon, B. Mantilla, Eduardo Tuta Quintero, G.A. Hincapie Diaz, Elías Quintero Muñoz, David Acosta Hernández, Camila Martínez Ayala","doi":"10.37897/rmj.2022.4.8","DOIUrl":"https://doi.org/10.37897/rmj.2022.4.8","url":null,"abstract":"Introduction. Sleep apnea syndrome (SAS) can accompany patients with chronic primary headache (CPH), being a frequent cause of persistence of symptoms in these patients, however, the data studying this disorder in patients with CPH are still limited. Objective. To determine the frequency of SAS in patients with CPH. Methods. A retrospective cohort was analyzed in patients with a diagnosis of CPH in a third level hospital. CPH was diagnosed according to the criteria of the International Headache Society and SAS with a polysomnographic record with an apnea-hypopnea index (AHI) >5/h, the frequency of SAS was determined among the total number of patients with AHI >5/h over the total number of patients undergoing polysomnography. Results. A total of 114 subjects were included, where the SAS in CPH was 83.3%, of which 56.8% were men and 60% older than 50 years; 89% of the population had a body mass index (BMI) greater than 27 kg/m2. Fatigue and sleepiness during the day were the most frequent symptoms, reported in 89.5% of the population with SAS compared to 47.4% of the population without a diagnosis of SAS. Conclusion. Sleep apnea is a frequent condition in patients with CPH undergoing polysomnography, mainly overweight men over 50 years of age. The main associated symptoms are fatigue and sleepiness.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77166713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Poposki, M. Bosilkovski, K. Grozdanovski, Z. Sopova, Arlinda Osmani, D. Jakimovski, D. Georgievska, T. Milenković
Objectives. The aim is to describe the phenotypic, biological and clinical characteristics of hospitalized patients with COVID-19 and diabetes, and the association with the clinical outcome of the patients. Material and methods. This single-center, retrospective study was conducted on 200 patients. The primary endpoint was death observed within day 7, 14 and beyond day 14 of hospitalization, and secondary objective was to compare the survival group with non-survival group. The variables that demonstrated significant association with primary endpoint were subject to multivariate binary logistic regression analysis. Outcomes. The estimated prevalence was 17.87% of the total COVID-19 hospitalizations during this period (n=1119). The majority of the patients were with diabetes mellitus type 2 with a median age of 67 years and BMI of 27.8 kg/m2. On admission, 156 patients (78%) presented with severe/critical illness. A total of 93 patients (46.5%) met the primary endpoint, with most deaths occurring within day 7 of hospital stay. Non-survival group showed significantly higher levels of leucocytes count, more pronounced lymphopenia, higher CRP, LDH and D-dimer levels. Multivariate analysis identified four independent risk factors associated with death: age OR 1.05 (CI 95% 1.01-1.09), severity of disease at admission OR 0.22 (CI 95, 0.07-0.65), COVID-19 vaccination status OR 3.07 (CI 95%, 1.36-6.91) and LDH levels OR 1.00 (CI 95%,1.002-1.008). Conclusions. Diabetic patients admitted to hospital for COVID-19 infection tend to have high mortality rate. Severity of disease at admission, advanced age, not completed vaccination and increased LDH levels are independent risk factors for lethal outcome, irrespective of diabetes status.
{"title":"Phenotypic characteristics and clinical outcome in hospitalized patients with COVID-19 and diabetes","authors":"K. Poposki, M. Bosilkovski, K. Grozdanovski, Z. Sopova, Arlinda Osmani, D. Jakimovski, D. Georgievska, T. Milenković","doi":"10.37897/rmj.2022.4.6","DOIUrl":"https://doi.org/10.37897/rmj.2022.4.6","url":null,"abstract":"Objectives. The aim is to describe the phenotypic, biological and clinical characteristics of hospitalized patients with COVID-19 and diabetes, and the association with the clinical outcome of the patients. Material and methods. This single-center, retrospective study was conducted on 200 patients. The primary endpoint was death observed within day 7, 14 and beyond day 14 of hospitalization, and secondary objective was to compare the survival group with non-survival group. The variables that demonstrated significant association with primary endpoint were subject to multivariate binary logistic regression analysis. Outcomes. The estimated prevalence was 17.87% of the total COVID-19 hospitalizations during this period (n=1119). The majority of the patients were with diabetes mellitus type 2 with a median age of 67 years and BMI of 27.8 kg/m2. On admission, 156 patients (78%) presented with severe/critical illness. A total of 93 patients (46.5%) met the primary endpoint, with most deaths occurring within day 7 of hospital stay. Non-survival group showed significantly higher levels of leucocytes count, more pronounced lymphopenia, higher CRP, LDH and D-dimer levels. Multivariate analysis identified four independent risk factors associated with death: age OR 1.05 (CI 95% 1.01-1.09), severity of disease at admission OR 0.22 (CI 95, 0.07-0.65), COVID-19 vaccination status OR 3.07 (CI 95%, 1.36-6.91) and LDH levels OR 1.00 (CI 95%,1.002-1.008). Conclusions. Diabetic patients admitted to hospital for COVID-19 infection tend to have high mortality rate. Severity of disease at admission, advanced age, not completed vaccination and increased LDH levels are independent risk factors for lethal outcome, irrespective of diabetes status.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89580384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Toma, M. Iriciuc, Vlad Dima, R. Bohîlțea, A. Bivoleanu
The paper presents the clinical, ultrasound and MRI appearances in the case of the closed spinal dysraphisms with a cutaneous/ subcutaneous mass: lypomyelomeningocele, posterior meningocele and cervical meningocele. There is mentioned first the classification of these defects, then, for each type, a case example is presented, showing the clinical aspect of the lesion, the ultrasound features and the correlation of ultrasound with MRI images. The examples show a good correlation between ultrasound and MRI, entitling the ultrasound exam to be the first line of exploration in the case of this category of patients.
{"title":"The role of spinal ultrasound in the diagnosis of spinal dysraphism – correlation with MRI examination","authors":"A. Toma, M. Iriciuc, Vlad Dima, R. Bohîlțea, A. Bivoleanu","doi":"10.37897/rmj.2022.4.1","DOIUrl":"https://doi.org/10.37897/rmj.2022.4.1","url":null,"abstract":"The paper presents the clinical, ultrasound and MRI appearances in the case of the closed spinal dysraphisms with a cutaneous/ subcutaneous mass: lypomyelomeningocele, posterior meningocele and cervical meningocele. There is mentioned first the classification of these defects, then, for each type, a case example is presented, showing the clinical aspect of the lesion, the ultrasound features and the correlation of ultrasound with MRI images. The examples show a good correlation between ultrasound and MRI, entitling the ultrasound exam to be the first line of exploration in the case of this category of patients.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78620897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Plotogea, C. Mehedințu, V. Varlas, Francesca Frîncu, R. Mateescu, A. Edu, Vlad Dima, C. Andreescu, A. Petca, Denisa-Andreea Dorneanu
The fetal growth normally depends on sufficient delivery of oxygen and nutrients mainly via the placenta. Inadequate fetal nutrition may result in poor development and adaptation that permanently alter the fetus' metabolism and physiology. Intrauterine Growth Restriction is defined as a deviation on the fetal growth pattern. An estimated fetal weight (EFW) that is below the 10th percentile for gestational age is commonly used to describe fetal growth restriction. Usually obtained sonographically, there is evidence that ultrasound imaging of the uterine artery, middle cerebral artery, and fetal umbilical artery during the late third-trimester (approximately 35-37 weeks) significantly improves the detection and diagnosis of IUGR. In obstetrics, an increased risk of perinatal mortality and morbidity is associated with the diagnosis of IUGR.
{"title":"Managing intrauterine growth restriction","authors":"M. Plotogea, C. Mehedințu, V. Varlas, Francesca Frîncu, R. Mateescu, A. Edu, Vlad Dima, C. Andreescu, A. Petca, Denisa-Andreea Dorneanu","doi":"10.37897/rmj.2022.4.2","DOIUrl":"https://doi.org/10.37897/rmj.2022.4.2","url":null,"abstract":"The fetal growth normally depends on sufficient delivery of oxygen and nutrients mainly via the placenta. Inadequate fetal nutrition may result in poor development and adaptation that permanently alter the fetus' metabolism and physiology. Intrauterine Growth Restriction is defined as a deviation on the fetal growth pattern. An estimated fetal weight (EFW) that is below the 10th percentile for gestational age is commonly used to describe fetal growth restriction. Usually obtained sonographically, there is evidence that ultrasound imaging of the uterine artery, middle cerebral artery, and fetal umbilical artery during the late third-trimester (approximately 35-37 weeks) significantly improves the detection and diagnosis of IUGR. In obstetrics, an increased risk of perinatal mortality and morbidity is associated with the diagnosis of IUGR.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83827794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}