This study investigates the inlet airflow velocity and the maximum temperature of the smoke layer underneath the ceiling in naturally ventilated inclined tunnels by means of CFD simulations and theoretical analysis. The findings of this research indicate that the chimney-effect induced inlet airflow velocity is proportional to the power of the tunnel height difference () and fire heat release rate (HRR). However, the smoke stratification occurring downstream of the fire source exerts a significant influence on the inlet airflow velocity. It is also illustrated that the maximum temperature of the smoke layer underneath the tunnel ceiling highly depends on the HRR and tunnel height difference, rather than being solely determined by the tunnel slope. The position of the maximum temperature is found to be closely related to the tunnel height difference, but independent of HRR. A predictive model has been devised to estimate the maximum smoke temperature underneath the tunnel ceiling. Comparative study of the smoke maximum temperature between naturally ventilated inclined tunnels and longitudinal ventilated horizontal tunnels shows that the influence of fire heat release rate on the smoke maximum temperature of inclined tunnels is less pronounced than that of horizontal tunnels.