Pub Date : 2020-09-17DOI: 10.32932/rpia.2020.09.041
A. Rodolfo, Fernando Friões, Josefina Cernadas
{"title":"Caso de reação de hipersensibilidade a fármaco de emergência médica – Novo protocolo de dessensibilização","authors":"A. Rodolfo, Fernando Friões, Josefina Cernadas","doi":"10.32932/rpia.2020.09.041","DOIUrl":"https://doi.org/10.32932/rpia.2020.09.041","url":null,"abstract":"","PeriodicalId":21399,"journal":{"name":"Revista Portuguesa de Imunoalergologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47814945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-16DOI: 10.32932/rpia.2020.06.033
Marta Martins, B. Cardoso, Sofia Farinha, Rute Reis, Elza Tomaz, Filipe Inácio
Background: Adherence to therapy in bronchial asthma is essential for the control of the disease. Several studies show that non -adherence seems to be the result of different factors and barriers associated with the patient, but also with the prescriber. The most important are the psychological, economic and social aspects. In clinical practice, there are few resources that allow the physician to objectify the degree of compliance of his prescription. The aim of this study was to analyze the degree of adherence to therapy in asthmatic patients followed in a Hospital Immunoallergology Department. Methods: The clinical trials of 63 asthmatic patients followed at the Immunoallergology Department from January to December of 2016 (T0) and from January to December of 2017 (T1) were retrospectively studied. The number of packs prescribed to the patients by the attending physician and the number of packs actually purchased in pharmacies were analyzed in T0 and T1 by means of Electronic Medicines Prescriptions (PEM) records for the following drugs: bronchodilators (BD), inhaled corticosteroids isolated or in combination with bronchodilators (OUT), oral antihistamines (AH), leukotriene antagonists (LCRA), nasal corticosteroids (CN) and oral corticosteroids (CO). The following demographic and clinical variables were analyzed: age, sex, clinical diagnosis, atopy, allergen sensitization and specif ic immunotherapy treatment (ITE). Results: We found a compliance of 64.76% to the prescription. The drugs which the patients most adhere were oral corticosteroids (73%), followed by leukotriene antagonists and antihistamines (70%). When analysing associations between variables, it was observed that patients who were not under ITE had greater adhesion to the inhalers (BD and CI) (p <0.05). The asthmatic group had a positive association with adherence to the LCRA (p <0.05) and in the analysis by age, we found that the infant population had a positive association with adherence to AH (p <0.05). Conclusions: To improve adherence to therapy in asthma, it is important to address and know patient’s compliance. The study of each patient’s adherence based on computerized drug prescription and retrieval systems in pharmacies allows prescribing physicians to introduce this variable into the analysis of asthma control.
{"title":"Adesão à terapêutica na asma","authors":"Marta Martins, B. Cardoso, Sofia Farinha, Rute Reis, Elza Tomaz, Filipe Inácio","doi":"10.32932/rpia.2020.06.033","DOIUrl":"https://doi.org/10.32932/rpia.2020.06.033","url":null,"abstract":"Background: Adherence to therapy in bronchial asthma is essential for the control of the disease. Several studies show that non -adherence seems to be the result of different factors and barriers associated with the patient, but also with the prescriber. The most important are the psychological, economic and social aspects. In clinical practice, there are few resources that allow the physician to objectify the degree of compliance of his prescription. The aim of this study was to analyze the degree of adherence to therapy in asthmatic patients followed in a Hospital Immunoallergology Department. Methods: The clinical trials of 63 asthmatic patients followed at the Immunoallergology Department from January to December of 2016 (T0) and from January to December of 2017 (T1) were retrospectively studied. The number of packs prescribed to the patients by the attending physician and the number of packs actually purchased in pharmacies were analyzed in T0 and T1 by means of Electronic Medicines Prescriptions (PEM) records for the following drugs: bronchodilators (BD), inhaled corticosteroids isolated or in combination with bronchodilators (OUT), oral antihistamines (AH), leukotriene antagonists (LCRA), nasal corticosteroids (CN) and oral corticosteroids (CO). The following demographic and clinical variables were analyzed: age, sex, clinical diagnosis, atopy, allergen sensitization and specif ic immunotherapy treatment (ITE). Results: We found a compliance of 64.76% to the prescription. The drugs which the patients most adhere were oral corticosteroids (73%), followed by leukotriene antagonists and antihistamines (70%). When analysing associations between variables, it was observed that patients who were not under ITE had greater adhesion to the inhalers (BD and CI) (p <0.05). The asthmatic group had a positive association with adherence to the LCRA (p <0.05) and in the analysis by age, we found that the infant population had a positive association with adherence to AH (p <0.05). Conclusions: To improve adherence to therapy in asthma, it is important to address and know patient’s compliance. The study of each patient’s adherence based on computerized drug prescription and retrieval systems in pharmacies allows prescribing physicians to introduce this variable into the analysis of asthma control.","PeriodicalId":21399,"journal":{"name":"Revista Portuguesa de Imunoalergologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44550658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-16DOI: 10.32932/rpia.2020.06.034
J. Carvalho, Centro Hospitalar e Universitário de Coimbra Serviço de Imunoalergologia, Iolanda Coutinho, Inês Nunes, A. L. Moura, Frederico S. Regateiro
{"title":"Asma e COVID-19: Atualização","authors":"J. Carvalho, Centro Hospitalar e Universitário de Coimbra Serviço de Imunoalergologia, Iolanda Coutinho, Inês Nunes, A. L. Moura, Frederico S. Regateiro","doi":"10.32932/rpia.2020.06.034","DOIUrl":"https://doi.org/10.32932/rpia.2020.06.034","url":null,"abstract":"","PeriodicalId":21399,"journal":{"name":"Revista Portuguesa de Imunoalergologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47092005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-16DOI: 10.32932/rpia.2020.06.035
Á. Rodolfo, Centro Hospitalar de São João Epe Porto Serviço de Imunoalergologia, F. Pina, M. Miranda, J. Plácido, Centro Hospitalar de São João Epe Porto Serviço de Urologia
Urticaria and angioedema are part of a benign syndrome in the majority of cases. However, they can occur as paraneoplastic syndromes. A 46 year old woman was observed with urticaria, angioedema and progressive fatigue and adynamia of unknown cause. The urticaria responded to anti -histamines, but the angioedema did not and had a circadian evolution. The urticaria was mild, but the angioedema caused severe episodes. Blood tests revealed normal red and white blood cell counts as, normal renal, liver and thyroid function. Sedimentation rate, complement serum proteins (C1, C3, C4 and C1q) and C1 -esterase inhibitor concentrations were within normal ranges. A CT -scan demonstrated a 4.8 cm diameter cyst in the right kidney, deemed as a probable renal cells carcinoma on a posterior Uro -CT-scan. A radical nefro -ureterectomy was successfully performed and tumor histology established a cromophobe renal cells carcinoma (RCC) diagnosis at a pTNM pT1b Nx R0. A few days after surgery, a fast improvement of facial angioedema was observed and one month later its complete disappearance was ascertained, without any recurrence during a subsequent one -year follow -up. The evaluation of patients with urticaria and angioedema does not usually require a lot of complementary tests. However, further study should be considered when these symptoms are present with atypical characteristics.
{"title":"Urticaria-angioedema paraneoplastic syndrome associated with renal cell carcinoma","authors":"Á. Rodolfo, Centro Hospitalar de São João Epe Porto Serviço de Imunoalergologia, F. Pina, M. Miranda, J. Plácido, Centro Hospitalar de São João Epe Porto Serviço de Urologia","doi":"10.32932/rpia.2020.06.035","DOIUrl":"https://doi.org/10.32932/rpia.2020.06.035","url":null,"abstract":"Urticaria and angioedema are part of a benign syndrome in the majority of cases. However, they can occur as paraneoplastic syndromes. A 46 year old woman was observed with urticaria, angioedema and progressive fatigue and adynamia of unknown cause. The urticaria responded to anti -histamines, but the angioedema did not and had a circadian evolution. The urticaria was mild, but the angioedema caused severe episodes. Blood tests revealed normal red and white blood cell counts as, normal renal, liver and thyroid function. Sedimentation rate, complement serum proteins (C1, C3, C4 and C1q) and C1 -esterase inhibitor concentrations were within normal ranges. A CT -scan demonstrated a 4.8 cm diameter cyst in the right kidney, deemed as a probable renal cells carcinoma on a posterior Uro -CT-scan. A radical nefro -ureterectomy was successfully performed and tumor histology established a cromophobe renal cells carcinoma (RCC) diagnosis at a pTNM pT1b Nx R0. A few days after surgery, a fast improvement of facial angioedema was observed and one month later its complete disappearance was ascertained, without any recurrence during a subsequent one -year follow -up. The evaluation of patients with urticaria and angioedema does not usually require a lot of complementary tests. However, further study should be considered when these symptoms are present with atypical characteristics.","PeriodicalId":21399,"journal":{"name":"Revista Portuguesa de Imunoalergologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46764986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-16DOI: 10.32932/rpia.2020.06.036
A. Rodolfo, A. Maia, Artur Bonito-Vítor
{"title":"Eczema herpeticum: A propósito de um caso clínico","authors":"A. Rodolfo, A. Maia, Artur Bonito-Vítor","doi":"10.32932/rpia.2020.06.036","DOIUrl":"https://doi.org/10.32932/rpia.2020.06.036","url":null,"abstract":"","PeriodicalId":21399,"journal":{"name":"Revista Portuguesa de Imunoalergologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41808063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-01DOI: 10.32932/rpia.2020.06.032
T. Rama, Centro Hospitalar Universitário São João Porto Serviço de Imunoalergologia
{"title":"COVID-19: Formação específica em Imunoalergologia em tempos de incerteza","authors":"T. Rama, Centro Hospitalar Universitário São João Porto Serviço de Imunoalergologia","doi":"10.32932/rpia.2020.06.032","DOIUrl":"https://doi.org/10.32932/rpia.2020.06.032","url":null,"abstract":"","PeriodicalId":21399,"journal":{"name":"Revista Portuguesa de Imunoalergologia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41328271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-25DOI: 10.32932/rpia.2019.07.017
C. Valente, Isabel Rosmaninho
{"title":"Prurido crónico – Da etiologia ao tratamento","authors":"C. Valente, Isabel Rosmaninho","doi":"10.32932/rpia.2019.07.017","DOIUrl":"https://doi.org/10.32932/rpia.2019.07.017","url":null,"abstract":"","PeriodicalId":21399,"journal":{"name":"Revista Portuguesa de Imunoalergologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45903673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-25DOI: 10.32932/rpia.2019.07.020
M. Marques, Centro Hospitalar e Universitário do Porto Serviço de Imunoalergologia, A. Machado, Inês Lobo
{"title":"Alergia a budesonido intranasal: Um suspeito incomum","authors":"M. Marques, Centro Hospitalar e Universitário do Porto Serviço de Imunoalergologia, A. Machado, Inês Lobo","doi":"10.32932/rpia.2019.07.020","DOIUrl":"https://doi.org/10.32932/rpia.2019.07.020","url":null,"abstract":"","PeriodicalId":21399,"journal":{"name":"Revista Portuguesa de Imunoalergologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47700459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-25DOI: 10.32932/rpia.2019.07.016
S. Rosa, M. Sousa, P. Pinto
Atopic eczema (AE) is a chronic inflammatory disease very common in children. In most cases, clinical control is achieved with adequate hydration (emollients) and topical treatment (topical corticosteroids, topical calcineurin inhibitors) but there is a subgroup of patients with severe AE unresponsive to treatment or who experience relapse after reduction of anti -inflammatory Sónia Rosa1, Maria João Sousa2, Paula Leiria Pinto3 1 Serviço de Imunoalergologia do Hospital de Dona Estefânia, Centro Hospitalar Universitário de Lisboa Central – CHULC 2 Serviço de Imunoalergologia do Hospital de Gaia, Centro Hospitalar Vila Nova de Gaia/Espinho – EPE 3 Serviço de Imunoalergologia do Hospital de Dona Estefânia, Centro Hospitalar Universitário de Lisboa Central – CHULC R e v P o r t I m u n o a l e r g o l o g i a 2 0 1 9 ; 2 7 ( 3 ) : 2 0 5 2 1 8 Data de receção / Received in: 25/11/2018 Data de aceitação / Accepted for publication in: 16/01/2019 http://doi.org/10.32932/rpia.2019.07.016 206 R E V I S T A P O R T U G U E S A D E I M U N O A L E R G O L O G I A Sónia Rosa, Maria João Sousa, Paula Leiria Pinto
特应性湿疹是一种常见于儿童的慢性炎症性疾病。在大多数情况下，临床控制是通过充分的水合作用（润肤剂）和局部治疗（局部皮质类固醇、局部钙调神经磷酸酶抑制剂）来实现的，但也有一组严重AE患者对治疗无反应，或在抗炎药Sónia Rosa1、Maria João Sousa2、，Paula Leiria Pinto3 1里斯本中央大学中央医院Dona Estefânia医院的免疫变态反应学服务-CHULC 2新维拉医院/埃斯皮诺中心的盖亚医院的免疫过敏反应学服务-EPE 3，里斯本中央大学医院-CHULC R e v P o R t I m u n o a l e R g o l o g I a 2 0 1 9；2 7（3）：2 0 5 2 1 8接收日期：2018年11月25日接收日期：2019年1月16日发布http://doi.org/10.32932/rpia.2019.07.016206 R E V I S T A P O R T U G U E S A D E I M U N O A L E R G O L O G I A Sónia Rosa、Maria JoãO Sousa、Paula Leiria Pinto
{"title":"Tratamento sistémico do eczema atópico grave em idade pediátrica","authors":"S. Rosa, M. Sousa, P. Pinto","doi":"10.32932/rpia.2019.07.016","DOIUrl":"https://doi.org/10.32932/rpia.2019.07.016","url":null,"abstract":"Atopic eczema (AE) is a chronic inflammatory disease very common in children. In most cases, clinical control is achieved with adequate hydration (emollients) and topical treatment (topical corticosteroids, topical calcineurin inhibitors) but there is a subgroup of patients with severe AE unresponsive to treatment or who experience relapse after reduction of anti -inflammatory Sónia Rosa1, Maria João Sousa2, Paula Leiria Pinto3 1 Serviço de Imunoalergologia do Hospital de Dona Estefânia, Centro Hospitalar Universitário de Lisboa Central – CHULC 2 Serviço de Imunoalergologia do Hospital de Gaia, Centro Hospitalar Vila Nova de Gaia/Espinho – EPE 3 Serviço de Imunoalergologia do Hospital de Dona Estefânia, Centro Hospitalar Universitário de Lisboa Central – CHULC R e v P o r t I m u n o a l e r g o l o g i a 2 0 1 9 ; 2 7 ( 3 ) : 2 0 5 2 1 8 Data de receção / Received in: 25/11/2018 Data de aceitação / Accepted for publication in: 16/01/2019 http://doi.org/10.32932/rpia.2019.07.016 206 R E V I S T A P O R T U G U E S A D E I M U N O A L E R G O L O G I A Sónia Rosa, Maria João Sousa, Paula Leiria Pinto","PeriodicalId":21399,"journal":{"name":"Revista Portuguesa de Imunoalergologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49373173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-25DOI: 10.32932/rpia.2019.07.019
A. Mesquita, A. Coimbra, J. Plácido
{"title":"Caso clínico: Urticária como síndrome paraneoplásica","authors":"A. Mesquita, A. Coimbra, J. Plácido","doi":"10.32932/rpia.2019.07.019","DOIUrl":"https://doi.org/10.32932/rpia.2019.07.019","url":null,"abstract":"","PeriodicalId":21399,"journal":{"name":"Revista Portuguesa de Imunoalergologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46107855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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