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Thyroid Autoantibodies in Type -1 Diabetic Mellitus Patients and their Correlation with Thyroid function and Tumor Necrotic Factor-Alpha 1型糖尿病患者甲状腺自身抗体及其与甲状腺功能和肿瘤坏死因子- α的关系
Pub Date : 2023-01-30 DOI: 10.25271/sjuoz.2023.11.1.1013
B. Shnawa, Abdulsameea Majeed Taha
Type 1 Diabetes Mellitus (T1DM) is a complicated autoimmune disorder initiated by T-cell-mediated damage of pancreatic beta cells, resulting in insulin deficiency and the development of hyperglycaemia. This disease is most common in childhood and adolescence and frequently co-occurs with other autoimmune conditions like autoimmune thyroiditis. This work aimed to investigate thyroid autoantibodies and their correlation with thyroid functions and tumour necrosis factor-alpha (TNF-α) in T1DM patients. Eighty participants were enrolled in a case-control study, including sixty T1DM patients and twenty healthy controls. Peripheral blood specimens were taken from individuals with proven T1DM and healthy individuals (control group). Body mass index (BMI), fasting blood sugar (FBS), glycated hemoglobulin (HbA1c), thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4), thyroid autoantibodies, including anti-thyroid peroxidase (anti-TPO) in addition to anti-thyroglobulin (anti-Tg), and TNF- α concentrations were evaluated in T1DM and control groups. Our findings revealed that thyroid autoantibodies were significantly more prevalent in T1DM patients, elevated TSH, and significantly higher TNF-α levels than in the control group, indicating an increased risk for inflammation based on cytokine levels. The current study proved that in T1DM patients' sera compared to the healthy control, thyroid autoantibodies and TNF-α levels were positively correlated. In conclusion, poor diabetes management and high TSH levels may indicate subclinical hypothyroidism, which impacts diabetes control. This is possibly linked to thyroid autoimmunity. Future research is needed to understand how TNF- αcontributes to the progression of diabetes disease and its complications.
1型糖尿病(T1DM)是一种复杂的自身免疫性疾病,由t细胞介导的胰腺β细胞损伤引发,导致胰岛素缺乏和高血糖的发展。这种疾病最常见于儿童和青少年,经常与其他自身免疫性疾病如自身免疫性甲状腺炎共同发生。本研究旨在探讨T1DM患者甲状腺自身抗体及其与甲状腺功能和肿瘤坏死因子-α (TNF-α)的相关性。80名参与者参加了一项病例对照研究,包括60名T1DM患者和20名健康对照者。外周血标本取自确诊T1DM患者和健康个体(对照组)。评估T1DM组和对照组的体重指数(BMI)、空腹血糖(FBS)、糖化血红蛋白(HbA1c)、促甲状腺激素(TSH)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、甲状腺自身抗体(除抗甲状腺球蛋白(anti-Tg)外,还包括抗甲状腺过氧化物酶(anti-TPO)和TNF- α浓度。我们的研究结果显示,与对照组相比,甲状腺自身抗体在T1DM患者中更为普遍,TSH升高,TNF-α水平显著升高,表明基于细胞因子水平的炎症风险增加。本研究证实,与健康对照相比,T1DM患者血清中甲状腺自身抗体与TNF-α水平呈正相关。总之,糖尿病管理不善和高TSH水平可能提示亚临床甲状腺功能减退,影响糖尿病控制。这可能与甲状腺自身免疫有关。未来的研究需要了解TNF- α如何促进糖尿病疾病及其并发症的进展。
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引用次数: 0
Nanostructured Silver Thin Film: Using Successive Ionic Layer Adsorption and Reduction Method 纳米结构银薄膜:连续离子层吸附还原法
Pub Date : 2023-01-30 DOI: 10.25271/sjuoz.2023.11.1.1017
Ari A. Yatem, M. S. Rammoo
The Successive Ionic Layer Adsorption and Reduction (SILAR) method was utilized to produce nanostructured silver thin films on a glass substrate. Ag nanoparticles were grown using SILAR parameters such as silver nitrate (AgNO3), reduction time, reduction agent in an aqueous solution of hydrazine hydrate with various concentrations, and growth cycles. In this study, X-ray diffraction (XRD), scanning electron microscopy (SEM), and UV-visible-NIR absorption spectroscopy techniques were used to assess the produced silver thin film nanostructure. The size and spreading of the formed silver nanoparticles are observed to grow with the reducing agent and eventually saturate for constant growth cycles. As a result, the size and the distribution of the produced Ag nanoparticles grow uniformly. Higher growth cycles, however, caused Ag nanoparticles to lose their homogeneity and change into gravel-shaped particles. Therefore, silver nanoparticles that have been produced with the ideal SILAR conditions can be employed as an extremely sensitive, repeatable substrate with an exceptionally efficient factor. Moreover, the Effect of the concentration of HyH on the properties of SILAR-grown silver thin films has been extensively studied.
采用连续离子层吸附还原(SILAR)方法在玻璃衬底上制备了纳米结构的银薄膜。利用硝酸银(AgNO3)、还原时间、还原剂在不同浓度水合肼水溶液中的作用以及生长周期等SILAR参数生长银纳米颗粒。采用x射线衍射(XRD)、扫描电镜(SEM)和紫外可见近红外吸收光谱技术对制备的银薄膜纳米结构进行了表征。观察到形成的银纳米颗粒的大小和扩散随着还原剂的增长而增长,并最终在恒定的生长周期中饱和。结果表明,制备的银纳米颗粒的尺寸和分布均匀。然而,较高的生长周期导致银纳米颗粒失去其均匀性,变成砾石形状的颗粒。因此,在理想的SILAR条件下生产的银纳米颗粒可以作为一种非常敏感、可重复的底物,具有非常有效的因子。此外,HyH浓度对silar生长银薄膜性能的影响也得到了广泛的研究。
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引用次数: 0
Outdoor Air Contaminants-Heavy Metals and Associated Health Risks in Duhok-Iraq 杜霍克-伊拉克的室外空气污染物-重金属和相关健康风险
Pub Date : 2023-01-30 DOI: 10.25271/sjuoz.2023.11.1.1043
Samir Hashim Muhyadeen, Revink A. Ramadhan
Toxic elements in the atmosphere can cause a variety of health and environmental problems. The current work aims to assess the concentrations of heavy metals associated with the air in the Duhok city-Kurdistan Region of Iraq. For the first time a low volume sampling pump with Glass Microfiber Filter paper was used. Forty samples of air filter aerosol particles were collected from several areas in the Duhok city, during the dry and rainy seasons. Samples of air filters were prepared by a microwave digestion system and assessed by inductively coupled plasma Optical-Emission Spectrometry (ICP-OES). The average concentrations of Cr, Zn, Ni, Cd, Fe, and Pb found in 20 sites in the study area for the dry season were 0.004 mg/m3, 0.007 mg/m3, 0.003 mg/m3, 0.002 mg/m3, 0.142 mg/m3, and 0.402 mg/m3 respectively. Also, the average levels of the mentioned elements were 0.003 mg/m3, 0.004 mg/m3, 0.012 mg/m3, 0.003 mg/m3, 0.138 mg/m3, and 0.645 mg/m3 respectively in wet season. Seasonal results confirmed no significant differences in the concentrations of elements measured at all study sites, with the exception of lead, which doubles during the rainy season. Results showed that the levels of metal concentrations in the present study exceeded the standard limits of WHO. The results of the health risk assessment showed that the population in Duhok city had a higher lifetime chance of developing cancer as a result of these air concentrations and their heavy metal content.
大气中的有毒元素会引起各种健康和环境问题。目前的工作旨在评估伊拉克杜胡克-库尔德斯坦地区空气中重金属的浓度。首次使用了带有玻璃超细纤维滤纸的小体积取样泵。在旱季和雨季期间,从杜霍克市的几个地区收集了40个空气过滤器气溶胶颗粒样本。采用微波消解法制备了空气过滤器样品,并用电感耦合等离子体发射光谱法(ICP-OES)对样品进行了评价。研究区20个站点旱季Cr、Zn、Ni、Cd、Fe、Pb平均浓度分别为0.004 mg/m3、0.007 mg/m3、0.003 mg/m3、0.002 mg/m3、0.142 mg/m3和0.402 mg/m3。雨季平均含量分别为0.003 mg/m3、0.004 mg/m3、0.012 mg/m3、0.003 mg/m3、0.138 mg/m3和0.645 mg/m3。季节性结果证实,除铅外,所有研究地点测量的元素浓度没有显著差异,铅在雨季增加一倍。结果表明,本研究中的金属浓度水平超过了世界卫生组织的标准限值。健康风险评估的结果表明,由于这些空气浓度及其重金属含量,杜胡克市的人口一生中患癌症的机会更高。
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引用次数: 0
Quantification of the Relationship Between the Height – Diameter of (Pinus brutia Ten), Calabrian Pine Trees in Four Different Microsites in Duhok Governorate. Kurdistan Region, Iraq 杜胡克省4个不同样地卡拉布里亚松(Pinus brutia Ten)树高径关系的定量分析伊拉克库尔德斯坦地区
Pub Date : 2023-01-30 DOI: 10.25271/sjuoz.2023.11.1.1015
Tariq K. Salih, Hayfaa M. Saaed Abdulaziz
A sample of 120 trees was purposely selected from four different microsites (Behere, Swaratoka, Zawita, and Semel), (30 trees from each microsite) in the Duhok governorate. 100 of which were used for model calibration and the rest were used for validation of the selected regression equation. This study consisted of two main parts. In the first part  ,In the beginning, a scatter diagram was conducted for each microsite to detect the type of relationship between height and diameter at breast, which in turn will decrease the number of regression models that will be tested. Accordingly, 4 regression equations were developed for each of the four microsites separately. These models can be used to see how the ratio of height diameter in each of the studied sites is inter-correlated and which of them is the most appropriate for producing Calabrian pine trees.  In the second part, all microsites were then treated as one sample for estimating the parameters of 25 regression models using Excel and Statographic packageThe developed regression models underwent a screening process in order to find the most appropriate one to be used for the prediction of the height of Calabrian pine grown in the four mentioned microsites in Duhok governorate. Many measures of precision among them coefficient of determination, Bias%, Mean absolute error, Ohtomo’s unbiased test, Furnival Index, and AIC criterion were used for testing the performance of the developed equations in the prediction of the height. At last, the equation  was selected, as the best regression model. This equation shows that there is a linear relationship between  and a curvilinear relationship between D and H. The study showed that the height–diameter ratio was highest in Swaratoka and was the most appropriate microsite among the rest, followed by Behere, then Zawita and Semel came in last place.
120棵树的样本特意从杜胡克省的四个不同的微型站点(Behere、Swaratoka、Zawita和Semel)(每个微型站点30棵树)中选择。其中100个用于模型校正,其余用于所选回归方程的验证。本研究主要由两个部分组成。在第一部分中,首先对每个微站点进行散点图,以检测乳房高度与直径之间的关系类型,从而减少将要测试的回归模型的数量。据此,对4个微点分别建立了4个回归方程。这些模型可以用来观察每个研究地点的高径比是如何相互关联的,以及哪一个地点最适合种植卡拉布里亚松树。在第二部分中,将所有微点作为一个样本,使用Excel和Statographic软件包对25个回归模型的参数进行估计,并对所开发的回归模型进行筛选,以找到最合适的回归模型用于预测杜胡克省四个微点生长的卡拉布里亚松高度。采用确定系数、偏倚%、平均绝对误差、Ohtomo无偏检验、Furnival指数、AIC准则等精度指标检验所建立的方程对高度的预测效果。最后,选取该方程作为最佳回归模型。由方程可知,D与h之间存在线性关系和曲线关系。研究表明,高径比在Swaratoka最高,是最合适的微点,其次是Behere,最后是Zawita和Semel。
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引用次数: 0
Employing EMG sensors in Bionic limbs based on a New Binary Trick Method 基于二值欺骗的仿生肢体肌电传感器应用
Pub Date : 2023-01-29 DOI: 10.25271/sjuoz.2023.11.1.1027
M. G. Mohammed, Belnd Saadi Salih, Vaman Muhammed Haji
Human muscles can be read by using electromyography (EMG) sensors, which are electrical signals generated by the muscles of human and animal bodies. This means it is possible to use electricity generated by muscles to control actuators/servo motors for any specific tasks. This could support a wide range of applications, especially for people with disabilities. One such application would be making bionic limbs based on servo motors. According to a study held by the K4D helpdesk report based on estimations that 15.3% of the world’s population has a moderate or severe disability, this proportion is likely to increase to 18-20% in conflict- affected areas (Thompson, 2017). The goal of this study is to make bionic limbs affordable by minimizing the cost while maintaining accuracy at an acceptable rate. To achieve this goal, the study proposes a new idea for using electromyography (EMG) sensors in bionic limbs, which suggests a decrease in the number of EMG sensors to decrease the cost and power consumption. Decreasing the number of EMG sensors will result in a loss of accuracy in controlling actuators (servo motors) because usually, each sensor is responsible for activating one servo motor. In normal projects, one will need at least six EMG sensors to control six servo motors. The study will use only three EMG sensors to control/activate six servo motors depending on the binary trick idea suggested by this study, which is manipulating all three input signals from EMG sensors at once and then deciding which servo motor to activate by using a supervised machine learning technique such as K-nearest neighbors (kNN).
人体肌肉可以通过使用肌电图(EMG)传感器来读取,这是由人类和动物身体肌肉产生的电信号。这意味着可以使用肌肉产生的电力来控制执行器/伺服电机来完成任何特定的任务。这可以支持广泛的应用,特别是对残疾人。其中一个应用是制造基于伺服电机的仿生肢体。根据K4D服务台进行的一项研究报告,估计世界人口中有15.3%患有中度或重度残疾,在受冲突影响的地区,这一比例可能会增加到18-20% (Thompson, 2017)。本研究的目标是通过最小化成本,同时保持可接受的精度,使仿生肢体负担得起。为了实现这一目标,本研究提出了在仿生肢体中使用肌电传感器的新思路,即减少肌电传感器的数量,以降低成本和功耗。减少肌电传感器的数量将导致控制执行器(伺服电机)的精度下降,因为通常情况下,每个传感器负责激活一个伺服电机。在正常项目中,至少需要6个肌电传感器来控制6个伺服电机。该研究将仅使用三个肌电传感器来控制/激活六个伺服电机,这取决于本研究提出的二值技巧思想,即同时操作来自肌电传感器的所有三个输入信号,然后通过使用监督机器学习技术(如k -近邻(kNN))来决定激活哪个伺服电机。
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引用次数: 0
Mapping Flood Vulnerability by Applying EBF And AHP Methods, in the Iraqi Mountain Region 应用EBF和AHP方法绘制伊拉克山区洪水脆弱性
Pub Date : 2023-01-01 DOI: 10.25271/sjuoz.2023.11.1.1033
Abdulrazaq Qasim Mikail, R. Hamad
Flood hazards are a member of the world's catastrophic events with a hydrological climate origin. They are referred to as a situation in which the river flow and water level increase suddenly and cause human and financial losses. This research aims to determine flood-prone zones and evaluate the efficacy of RS and GIS-based evidence-based belief function (EBF) and hierarchical analysis (AHP) models in flood-prone area mapping. Using the Rezan River basin in the Mergasor area of Erbil governorate, Iraq, as an example, 11 factors such as slope, slope direction, land use, distance to the stream, distance to the road, elevation, soil, rainfall, geology, NDVI, and drainage density were utilized for flood moderation. The prediction rates of the EBF and AHP models were also analyzed to be 0.869% and 0.836%, respectively, indicating that these two models are better predictors. The findings of the study area revealed that 32% of the study area is under very high to high flooding hazard zones for the EBF method and 22% for the AHP method. This research’s conclusions are crucial for flood-prone region management, decision-making, and local administrative planning.
洪水灾害是世界性的灾难性事件之一,具有水文气候成因。它们被称为河流流量和水位突然增加并造成人员和经济损失的情况。本研究旨在确定洪水易发区,并评估基于RS和gis的循证信念函数(EBF)和层次分析法(AHP)模型在洪水易发区制图中的效果。以伊拉克埃尔比勒省Mergasor地区的Rezan河流域为例,利用坡度、坡度方向、土地利用、与河流的距离、与道路的距离、高程、土壤、降雨、地质、NDVI和排水密度等11个因素对洪水进行调节。EBF和AHP模型的预测率分别为0.869%和0.836%,表明EBF和AHP模型具有较好的预测效果。研究区结果显示,EBF法和AHP法分别有32%和22%的研究区处于极高至高洪水危险区。本研究的结论对洪水易发地区的管理、决策和地方行政规划具有重要意义。
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引用次数: 0
The Airborne Mycobiota of a Dust Storm in Comparison with a Calm Climate in Erbil City-Iraq 伊拉克埃尔比勒市一场沙尘暴与平静气候的空气真菌区系比较
Pub Date : 2023-01-01 DOI: 10.25271/sjuoz.2023.11.1.983
Salah Mahdi Saleem, Zean Zefenkey
A series of dust storms stroked Iraq from April to May 2022. These abnormal environmental events hold and transfer microorganisms far from their original sites. Mycobiome is a main part of the aerobiological aerosol, it includes agents of respiratory harm, opportunistic mycosis, as well as mycotoxin producers. 32 Petri dishes were exposed to the falling down dust for two days (S1). The time of exposure was 10 minutes per hour, a total of 8 samples/ day since 9:00 am. Sabouraud’s dextrose agar and pollen grains agar media were used. Sampling was identically repeated after two days during a calm climate (S2). Fungal genera, frequency%, and total similarity% were calculated for S1 and S2 samples.257 colonies (143CFU/m3) occurred in (S1) samples, in contrast, a total of 110 colonies from (S2) samples (59CFU/m3). The statistical analysis showed a highly significant difference between CFU for S1and S2 (p≤0.0001). Fifteen isolates were identified from (S1), and (5) from (S2). The highest occurrence O% and frequency F%  genera in S1   were, Aspergillus (65-6%; 15.9%), Alternaria (56.6%;11.2%), Cladosporium (46.8%; 13.6%), Penicillium(37.5%;8.1%), besides sterile mycelia, while in S2 were (40.6%; 30.6%) ; (25.0%; 17.2%); (32.0%; 26.3%) (34.3 %; 12.7%) respectively. The similarity between the fungal communities of the two times was low =35.7%.Results showed that air mycobiota on stormy days have a higher fungal abundance and diversity. All isolated fungi are adverse to humans, and animals.  Individuals who have respiratory problems or with weak immunity showed careful to protect themselves.
从2022年4月到5月,一系列沙尘暴袭击了伊拉克。这些异常的环境事件使微生物保持并转移到远离其原始位置的地方。真菌菌群是好氧气溶胶的主要组成部分,它包括呼吸道危害因子、机会性真菌病因子以及真菌毒素的产生因子。32个培养皿暴露于落尘中2天(S1)。暴露时间为每小时10分钟,从上午9:00开始共8个样本/天。采用沙伯氏葡萄糖琼脂和花粉粒琼脂培养基。在平静气候(S2)下,两天后重复相同的采样。计算S1和S2样品的真菌属、频率%和总相似度%。(S1)样品中有257个菌落(143CFU/m3), (S2)样品中有110个菌落(59CFU/m3)。统计分析显示s1和S2的CFU差异极显著(p≤0.0001)。从(S1)中分离出15株,从(S2)中分离出5株。S1中出现频率最高的O%和F%属为曲霉属(65-6%);15.9%),交替孢(56.6%;11.2%),枝孢菌(46.8%;13.6%),青霉菌(37.5%;8.1%),除无菌菌丝外,S2为(40.6%;30.6%);(25.0%;17.2%);(32.0%;26.3%) (34.3%;分别为12.7%)。两次真菌群落相似度较低,为35.7%。结果表明,暴雨天气空气真菌菌群真菌丰度和多样性较高。所有分离的真菌对人类和动物都是有害的。有呼吸系统疾病或免疫力较弱的人则小心地保护自己。
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引用次数: 2
Effects of Puncture Vine Plant (Tribulus Terrestris L.) Extract on All Larval Stages of Mosquito, Culex Pipiens (Diptera: Culicidae) 刺藤植物(蒺藜)的效应淡库蚊各幼虫期提取液(双翅目:库蚊科)
Pub Date : 2023-01-01 DOI: 10.25271/sjuoz.2023.11.1.981
Sara Ayoub Hassan, B. Al-Chalabi
The existing research was conducted in Duhok city to investigate the biological impact of extracting secondary chemical compounds from punctured vine plants (Tribulus terrestris L.) on the mortality of all larval stages of (Culex pipiens). Bioassay experiments were carried out by using solvent extraction methods and different concentrations (0.1,0.3,0.5,0.7) mg/ml. The results showed that the ethyl extract of puncture vine plant’s leaves demonstrated promising larvicidal activity, and fatal results were observed where the high rate of mortality was within the 1st larval instar 97.3% and 100% at a concentration(0.5 mg/ml) after 24 and 72 hours exposure respectively, while the lowest mortality rate was within the 4th larval instar 7.4% and 38% at a concentration(0,1mg/ml) after 24 and 72 hours exposure, respectively, also ,it was observed that the leaf extracts modified the morphology of the larval development stage. According to this initial research, those plants are possible alternatives to mosquito larvicide which can be used to produce cost-effective, safe chemicals to control mosquitoes.
本研究在杜霍克市进行了刺藤植物(蒺藜)次生化合物提取对淡色库蚊各幼虫期死亡率的生物学影响。采用不同浓度(0.1、0.3、0.5、0.7)mg/ml的溶剂萃取法进行生物测定实验。结果表明,刺藤叶乙酯提取物具有良好的杀虫活性,在0.5 mg/ml浓度下,24 h和72 h内1龄幼虫的死亡率最高,分别为97.3%和100%;在0、1mg/ml浓度下,24 h和72 h内4龄幼虫的死亡率最低,分别为7.4%和38%;此外,还观察到叶提取物改变了幼虫发育阶段的形态。根据这项初步研究,这些植物可能是杀蚊剂的替代品,可以用来生产成本低、安全的化学品来控制蚊子。
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引用次数: 0
Effects of Salicylic Acid on some Growth and Physiological Characteristics of Lettuce (Lactuca sativa L.) under Cadmium Stress Conditions 镉胁迫条件下水杨酸对莴苣生长和生理特性的影响
Pub Date : 2023-01-01 DOI: 10.25271/sjuoz.2023.11.1.987
Nazhad Khalid Talabany, I. M. Albarzinji
Lettuce (Lactuca sativa L.) is considered as the most cultivated and consumed leafy vegetable all over the world. In Erbil Governorate, most farmers used sewage water to irrigate lettuce, which caused health risks especially heavy metal pollutants including cadmium. This research was applied as a factorial experiment to investigate the effects of foliar spraying of salicylic acid (SA) (0,0.5,1, 1.5 or 2mM) followed by spraying cadmium chloride (Cd) (0, 1, 2, or 4mM) on the growth, and some physiological and biochemical characteristics of this plant. Results show that most vegetative growth characteristics responded inversely to increasing SA concentrations, whereas the response of root performance improved with using SA application. A low concentration of Cd (1mM) improved root and shoot performance, whereas increasing the concentration to 4 mM decreased these characteristics significantly compared to no Cd added plants, except for the percent of shoot dry matter. Most of photosynthetic pigments decreased significantly by foliar spraying with SA and Cd. Applications of SA increased catalase enzyme activity significantly compared to no SA treated plants. Cadmium foliar application increased peroxidase enzyme activity, ascorbic acid, proline, and percent of total carbohydrate content and decreased catalase enzyme activity and the percent of infection with watery soft rot significantly compared to no Cd treated plants. It is concluded that lettuce tolerance to cadmium stress was increased by pretreatment foliar application of SA.
莴苣(lacuca sativa L.)被认为是世界上种植和消费最多的叶菜。在埃尔比勒省,大多数农民使用污水灌溉生菜,这造成了健康风险,特别是镉等重金属污染物。采用析因试验研究了水杨酸(SA)(0、0.5、1、1.5和2mM)叶面喷施氯化镉(Cd)(0、1、2和4mM)对水杨酸(SA)生长和部分生理生化特性的影响。结果表明,随着SA浓度的增加,大部分营养生长特征呈负相关,而根系性能的响应随着SA浓度的增加而提高。低浓度Cd处理(1mM)提高了根和茎的性能,而当Cd处理增加到4mm时,除茎部干物质百分比外,其他性状均显著降低。叶面喷施SA和Cd显著降低了大部分光合色素的含量。喷施SA显著提高了过氧化氢酶活性。叶面施用镉显著提高了过氧化物酶活性、抗坏血酸、脯氨酸和总碳水化合物含量的百分比,显著降低了过氧化氢酶活性和水样软腐病侵染率。综上所述,叶面施用SA可提高生菜对镉胁迫的耐受性。
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引用次数: 2
Curcumin Gel Versus Chlorhexidine Gel for Treatment of Chronic Gingivitis Associated with Fixed Orthodontic Appliance 姜黄素凝胶与氯己定凝胶治疗固定矫治器相关性慢性牙龈炎的比较
Pub Date : 2023-01-01 DOI: 10.25271/sjuoz.2023.11.1.1010
Sawsan Ramadhan Hussein, S. Rashid
Background and aims: Gingivitis in orthodontic treatment remains a challenging and undesirable consequence of orthodontic treatment. Hence, a variety of chemical or herbal agents, methods, and techniques have been investigated to prevent or reduce gingivitis that occurs in orthodontic treatment. In this study, we will evaluate and compare the effect of curcumin (CMN) gel with chlorhexidine (CHX) gel on clinical parameters (plaque and gingival index) and oral bacterial number (total bacterial count test) in fixed orthodontic patients that have gingivitis. We are the first to use curcumin gel for patients that have gingivitis with fixed orthodontic appliances. Samples and Methods: Forty-five patients with fixed orthodontic appliances with metallic brackets that have generalized chronic dental plaque-induced gingivitis were selected randomly and divided into three groups - Group I (control), Group II (CMN), and Group III (CHX), respectively. Clinical parameters which are plaque index (PI) and gingival index (GI) were recorded at the baseline, 14 days, and 21 days of treatment, and a total bacterial count test (TBCT) was done for all the participants before and after treatment. Results: Both Curcumin and Chlorhexidine gel groups showed a significant reduction (P<0.05) in PI, GI, and TBCT compared to the control group at the end of treatment (after 21 days). However, there was no significant difference between Curcumin and Chlorhexidine gel groups (P>0.05). Conclusion: The results of this study show that curcumin and chlorhexidine gel have comparable anti-plaque, anti-gingivitis, and antibacterial activities and that both can be used to effectively treat plaque-induced gingivitis.
背景和目的:牙龈炎在正畸治疗中仍然是一个具有挑战性和不良的后果。因此,人们研究了各种化学或草药制剂、方法和技术来预防或减少正畸治疗中发生的牙龈炎。在本研究中,我们将评估和比较姜黄素(CMN)凝胶与氯己定(CHX)凝胶对牙龈炎固定正畸患者临床参数(菌斑和牙龈指数)和口腔细菌数量(总细菌计数试验)的影响。我们是第一个使用姜黄素凝胶的患者有固定正畸器具牙龈炎。样本与方法:随机选择45例患有广泛性慢性牙菌斑性牙龈炎的金属托槽固定正畸矫治器患者,将其分为I组(对照组)、II组(CMN组)和III组(CHX组)。在基线、治疗14天和治疗21天记录临床参数斑块指数(PI)和牙龈指数(GI),并在治疗前后对所有参与者进行总细菌计数测试(TBCT)。结果:姜黄素凝胶组和氯己定凝胶组均有显著性降低(P0.05)。结论:本研究结果表明姜黄素与氯己定凝胶具有相当的抗菌斑、抗牙龈炎和抗菌活性,均可有效治疗菌斑性牙龈炎。
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Science Journal of University of Zakho
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