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Electrochemical Sensor for Acetaminophen Based on a Poly(diphenylamine sulfonic acid) Modified Sensor 基于聚二苯胺磺酸修饰的对乙酰氨基酚电化学传感器
Pub Date : 2020-10-01 DOI: 10.1166/sl.2020.4285
G. Erdoğdu
A sensitive and simple modified sensor was prepared by electrodeposition of diphenylamine sulfonic acid (DPSA) to the glassy carbon electrode surface by cyclic voltammetry (CV) technique. The electrooxidation of Acetaminophen (AC) was accomplished by CV and differential pulse voltammetry at poly(DPSA) modified sensor. As a result of the findings, the current values were enhanced and both substances were separated at the modified sensor compared to the bare electrode. There was linearly between the oxidation current and concentration of AC from 0.0 to 100 μM in phospate buffer solution at pH 7.0. The limit of detection was 3.0 nM and the sensitivity was 0.4108 μA/μM. The determination of AC was successfully and satisfactorily carried out in real samples such as human blood serum and urine at the poly(DPSA) sensor. To the best knowledge of this work, this is the first study that detect the AC in the presence of ascorbic acid at poly(DPSA) sensor in the literature.
采用循环伏安法(CV)将二苯胺磺酸(DPSA)电沉积在玻碳电极表面,制备了一种灵敏、简便的改性传感器。在聚(DPSA)修饰的传感器上,利用CV和差分脉冲伏安法完成了对乙酰氨基酚(AC)的电氧化。由于这些发现,与裸电极相比,电流值得到了增强,两种物质在改进的传感器上被分离。在pH 7.0的磷酸盐缓冲溶液中,氧化电流与AC浓度在0.0 ~ 100 μM范围内呈线性关系。检测限为3.0 nM,灵敏度为0.4108 μA/μM。用聚(DPSA)传感器对人血清和尿液等实际样品进行了AC的测定,结果满意。据本工作所知,这是文献中第一个在聚(DPSA)传感器上检测抗坏血酸存在下AC的研究。
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引用次数: 0
Implementation of an Ultra Low Power Process-Insensitive Two Stage Complementary Metal Oxide Semiconductor Operational Amplifier with Enhanced Direct Current Gain at 45 nm Technology Node 45纳米技术节点上具有增强直流增益的超低功耗工艺不敏感两级互补金属氧化物半导体运算放大器的实现
Pub Date : 2020-10-01 DOI: 10.1166/sl.2020.4277
Pragati Gupta, S. Akashe
This paper presents an ultra low power process-insensitive two stage CMOS OP-AMP employing bulk-biasing technique realised in a standard 45 nm CMOS technology. Bulk-Biasing technique has been employed to augment the DC gain of two stage CMOS OP-AMP without having any impact on its power dissipation and output swing. In this work, high gain-bandwidth product (GBW) with appropriate phase margin is achieved through pseudo-cascode compensation approach which overcomes the drawbacks of Miller compensation technique also. Furthermore, the effect of width scaling on performance metrics of proposed OP-AMP has been analysed. The designed OP-AMP exhibits enhanced DC gain of 94.2 dB, gain-bandwidth product (GBW) of 460 MHz and adequate phase margin of 80°; with fast settling response. Also, the proposed OP-AMP has power dissipation of 27 μW and leakage current of 6.4 pA only. The design and optimisation of proposed OP-AMP is carried out at a power supply of 0.7 V under room temperature in Cadence Virtuoso tool.
本文提出了一种超低功耗、对工艺不敏感的两级CMOS运放,采用标准45纳米CMOS技术实现体积偏置技术。采用体偏置技术可以提高两级CMOS运算放大器的直流增益,而不影响其功耗和输出摆幅。本文采用伪级联码补偿方法,克服了米勒补偿技术的缺点,实现了具有适当相位裕度的高增益带宽积(GBW)。此外,还分析了宽度缩放对所提出的OP-AMP性能指标的影响。所设计的OP-AMP具有94.2 dB的增强直流增益,460 MHz的增益带宽积(GBW)和80°的充足相位裕度;具有快速的沉降响应。该放大器的功耗为27 μW,漏电流仅为6.4 pA。在Cadence Virtuoso工具中,在室温下以0.7 V的电源进行了所提出的OP-AMP的设计和优化。
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引用次数: 0
Sensitivity Enhancement of Surface Plasmon Resonance Sensor with Two Dimensional Materials Covered on Silver-Nickel Bimetallic Thin Solid Films 用银镍双金属薄膜覆盖二维材料增强表面等离子共振传感器的灵敏度
Pub Date : 2020-10-01 DOI: 10.1166/sl.2020.4284
L. Castañeda
In this paper a new sensing configuration with enhanced sensitivity utilizing 2D materials on the bimetallic layers of Magnetic Material Ni over Ag for Kretschmann configuration is proposed and analyzed numerically using Fresnel equation and transfer matrix method. Results show that such a hybrid configuration with well optimized thickness of metallic layer and utilization of specific no. of 2D materials can increases the sensitivity as high as 298°/RIU is absorbed for the configuration consist 10 nm of Ni over 40 nm thickness of Ag added with a 2 layers of WSe2.
本文提出了一种利用二维材料在磁性材料Ni / Ag双金属层上增强灵敏度的Kretschmann结构,并利用菲涅耳方程和传递矩阵法对其进行了数值分析。结果表明,这种混合结构具有较好的优化金属层厚度和比氮利用率。在厚度为40 nm的Ag上添加10 nm的Ni和2层WSe2,可以使二维材料的灵敏度提高到298°/RIU。
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引用次数: 0
Voltammetric Detection of Trace Elements in Various Biological Matrices 各种生物基质中微量元素的伏安法检测
Pub Date : 2020-10-01 DOI: 10.1166/sl.2020.4273
Hatice Gürünlüoğlu, G. Erdoğdu
The purpose of this work is to analyse Cu, Zn, Pb and Cd simultaneously in biological samples such as serum, hair, tooth and bone using differential pulse stripping voltammetry (DPSV). Therefore, suitable sample preparation and experimental conditions are determined. Trace metal concentrations of biological samples are measured and compared with the literature values. Cu, Zn and Pb are found in hair, tooth and bone samples while Cu and Zn metals is found in serum sample.
本工作的目的是利用差分脉冲溶出伏安法(DPSV)同时分析血清、头发、牙齿和骨骼等生物样品中的Cu、Zn、Pb和Cd。因此,确定了合适的样品制备和实验条件。测定了生物样品的痕量金属浓度,并与文献值进行了比较。头发、牙齿和骨骼样品中含有铜、锌和铅,血清样品中含有铜和锌金属。
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引用次数: 0
New Sensitivity Analysis on Graphene Nanoribbon Interconnects to Determine Importance of Parameters 石墨烯纳米带互连的新灵敏度分析确定参数的重要性
Pub Date : 2020-09-01 DOI: 10.1166/SL.2020.4272
Z. Zamini, Soroor Rahimi Khamaneh, A. Jadidi, Babak Roshanipour
In this paper sensitivity of a multilayer graphene nanoribbon (MGNR) interconnects parameters investigated. System sensitivity was studied on parameters like length and width in stable condition. The obtained results show with increasing width and length sensitivity will decrease and increase respectively. Impulse response diagram results show with increasing 50% width sensitivity will be zero but with increasing 50% length amplitude will decrease and the time of setting will increase. On the other hand from step response of transfer function, both width and length increase cause more stability for a system but the width parameter will be better choices for manipulating the dimension of MLGNR to reach the stable system.
本文研究了多层石墨烯纳米带(MGNR)互连参数的灵敏度。研究了系统在稳定状态下对长度、宽度等参数的灵敏度。结果表明,随着宽度和长度的增加,灵敏度分别减小和增大。脉冲响应图结果表明,当宽度增加50%时,灵敏度为零,而当长度增加50%时,振幅减小,整定时间增加。另一方面,从传递函数的阶跃响应来看,宽度和长度的增加都会增加系统的稳定性,但宽度参数是控制MLGNR尺寸以达到稳定系统的较好选择。
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引用次数: 0
Synthesis, Characterization, and Biological Evaluation of Novel Pseudomonas aeruginosa RTAC 11 Synthesized Ag Nanoparticles 新型铜绿假单胞菌RTAC 11合成银纳米颗粒的合成、表征及生物学评价
Pub Date : 2020-09-01 DOI: 10.1166/SL.2020.4271
Lavina Temkar, R. Tripathi, A. Tiwari, N. Kaur, A. Kirthi, A. Chaskar
Biological synthesis of silver nanoparticles (AgNPs) has been an area of research to avoid the harmful effects of the toxic chemicals used in its synthesis on our health and environment. In the present study, a novel strain of Pseudomonas aeruginosa-RTAC 11 isolated from soil was used for the synthesis of AgNPs. Characterization of the synthesized nanoparticles like UV-vis spectroscopy confirmed the synthesis of AgNPs through a signature peak at 420 nm. Fourier Transform Infrared (FTIR) spectroscopic analysis revealed the capping of AgNPs by proteins through signature functional groups. The nano-size of the particles were confirmed using scanning electron microscopy (SEM). The AgNPs showed good antibacterial activity against Escherichia coli ATCC 8739 and Staphylococcus aureus ATCC 6538, thus indicating an excellent antibacterial agent.
银纳米粒子的生物合成(AgNPs)一直是一个研究领域,以避免在其合成中使用的有毒化学品对我们的健康和环境的有害影响。本研究利用从土壤中分离的一株铜绿假单胞菌rtac 11合成AgNPs。对合成的纳米颗粒进行表征,如紫外可见光谱,通过420 nm的特征峰证实了AgNPs的合成。傅里叶变换红外(FTIR)光谱分析揭示了AgNPs被蛋白质通过特征官能团封盖。利用扫描电子显微镜(SEM)证实了颗粒的纳米尺寸。AgNPs对大肠杆菌ATCC 8739和金黄色葡萄球菌ATCC 6538具有良好的抑菌活性,是一种优良的抗菌剂。
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引用次数: 0
Weakly Nonlinear Double-Diffusive Oscillatory Magneto-Convection Under Gravity Modulation 重力调制下的弱非线性双扩散振荡磁对流
Pub Date : 2020-09-01 DOI: 10.1166/SL.2020.4281
P. Kiran, S. Manjula
An imposed time-periodic gravity field effect on double-diffusive magneto-convection for oscillatory mode has been investigated. The gravity field consisting of steady and periodic modes. A layer is confined with an electrically conducting fluid with Boussines q approximation and heated from below cooled from above. While using the perturbation technique we study nonlinear double-diffusive convection just above the critical state of the onset convection. The growth rate of the disturbances is confined with a critical Rayleigh number to investigate oscillatory convection. Analysis of finite- amplitude convection has been derived through the complex Ginzburg-Landau equation (CGLE). The convective heat and mass transfer obtained through CGLE at third-order under solvability conditions. This convective amplitude is required to estimate heat and mass transfer in terms of the Nusselt and Sherwood numbers. It is found that increasing the frequency of modulation causes diminishing heat and mass transfer. The effect of Prandtl number Pr, magnetic Prandtl number Pm, and amplitude δ enhances heat/mass transfer. It is found that an oscillatory mode of convection enhances the heat and mass transfer than the stationary mode. Further, streamlines, isotherms, and isohalines have their usual nature on double-diffusive magnetoconvection.
研究了双扩散磁对流振荡模式下外加时间周期重力场效应。由稳定模式和周期模式组成的重力场。一层被布西尼斯q近似的导电流体约束,从下加热从上冷却。采用微扰技术研究了刚超过起始对流临界状态的非线性双扩散对流。用临界瑞利数来限制扰动的增长速度,以研究振荡对流。利用复金兹堡-朗道方程(CGLE)导出了有限振幅对流的分析。在可解条件下,用CGLE计算三阶对流传热传质。用努塞尔和舍伍德数来估计传热和传质需要这个对流振幅。研究发现,增加调制频率可以减小传热传质。普朗特数Pr、磁普朗特数Pm和振幅δ的作用增强了传热传质。研究发现振荡对流模式比静止对流模式更有利于传热传质。此外,流线、等温线和等盐线在双扩散磁对流中具有其通常的性质。
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引用次数: 2
Design and Performance Analysis of Application Specific Integrated Circuit for Internet of Things Applications 面向物联网应用的专用集成电路设计与性能分析
Pub Date : 2020-09-01 DOI: 10.1166/sl.2020.4239
Vivek Pogra, Amandeep Singh, S. Vishvakarma, B. Raj
This paper proposes a novel design of application specific integrated circuit (ASIC) which is capable of connecting sensor network and other electronic systems to the internet. The transfer of data between different networks and electronic systems is controlled by internet of things (IoT) platform with the help of instruction sent to ASIC. ASIC will act as serial peripheral interface (SPI) master to all connected networks and data will be transferred serially between them. The different ASIC modules are SPI module, control module, memory module and data/instruction decoder with additional modules built-in self-test (BIST) and direct memory access (DMA). The proposed ASIC will consume less power as compared to conventional microcontroller/microprocessor due to SPI feature along with DMA on ASIC for IoT applications. It is described in very high speed integrated circuit hardware description language (VHDL) at register transfer level (RTL) and simulation is done on the Vivado 2016.2.
本文提出了一种新型的专用集成电路(ASIC),它能够将传感器网络和其他电子系统连接到互联网。不同网络和电子系统之间的数据传输由物联网(IoT)平台通过向ASIC发送指令来控制。ASIC将作为所有连接网络的串行外设接口(SPI)主机,数据将在它们之间串行传输。不同的ASIC模块是SPI模块,控制模块,内存模块和数据/指令解码器与附加模块内置自检(BIST)和直接内存访问(DMA)。由于SPI功能以及用于物联网应用的ASIC上的DMA,与传统的微控制器/微处理器相比,拟议的ASIC将消耗更少的功耗。在寄存器传输级(RTL)用超高速集成电路硬件描述语言(VHDL)进行描述,并在Vivado 2016.2上进行仿真。
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引用次数: 0
Monte Carlo Modelling of Magnetic and Thermodynamic Features of Rb3CoCl5 and Dy3Al5O12 Magnetic Systems Rb3CoCl5和Dy3Al5O12磁性体系磁性和热力学特征的蒙特卡罗建模
Pub Date : 2020-09-01 DOI: 10.1166/SL.2020.4283
A. Hendi, A. Bamuqaddam, S. Aldaghfag, F. Alkallas, M. Almoneef, M. Alanazi, A. Laref, N. Alsaif, M. Awad, A. Altowyan, K. Ortashi, J. Alzahrani
In our simulations, we considered two typical magnetic materials, while the first one includes the 3d-transition metal, such as cobalt which is responsible of the presence of magnetism in pyrochlore structure Rb3CoCl5. The second magnetic material was chosen to have 4f-rare earth metal, namely dysprosium that can induce magnetism in garnet material Dy3Al5O12. A general agreement was found between our results and the previous works. In our calculations, we employed the classical Ising model for the above mentioned realistic materials. We specifically studied the magnetic properties over a range of temperature including the critical temperature and above it. To understand the magnetic phase transition, the effect of magnetic field was involved in the classical Ising model.
在我们的模拟中,我们考虑了两种典型的磁性材料,而第一个包括3d过渡金属,例如钴,它负责在焦绿石结构Rb3CoCl5中存在磁性。第二种磁性材料选择含有4f稀土金属,即镝,它能在石榴石材料Dy3Al5O12中产生磁性。我们的结果与前人的工作基本一致。在我们的计算中,我们对上述现实材料采用了经典的Ising模型。我们专门研究了在一定温度范围内的磁性,包括临界温度和高于临界温度。为了理解磁相变,在经典的Ising模型中加入了磁场的影响。
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引用次数: 0
Improved Performance of Platinum Diselenide Based Surface Plasmon Resonance Biosensor Using Silicon 硅基二硒化铂表面等离子体共振生物传感器的性能改进
Pub Date : 2020-09-01 DOI: 10.1166/SL.2020.4279
R. Tiwari, Sachin Singh, R. Yadav, P. Lohia, D. K. Dwivedi
After the discovery of graphene in 2004, two-dimensional materials have attracted attention at large scale because of their peculiar structure and extraordinary properties. As they have large potential in future nano electronics, two-dimensional transition metal dichalcogenides has become most focus topic of study. Transition metal dichalcogenides with tunable finite band gap and significant transitional behavior are much suitable for the construction of electronic and optoelectronic devices of high-performance. However, platinum diselenide is group-10 transition metal dichalcogenides which occur naturally in one phase transition, which has been theoretically predicted as an excellent material. The proposed structure of surface plasmon resonance (SPR) -based biosensor consists of a silicon and two-dimensional nanomaterial platinum diselenide. The performance parameters of proposed biosensor (surface plasmon resonance-based) such as detection accuracy, figure of merit, sensitivity, full width at half maximum have been investigated. The sensitivity, detection accuracy, full width half maximum and figure of merit of proposed surface plasmon resonance biosensor having silver (50 nm), silicon (2 nm) and one layer of platinum diselenide with 2 nm thickness at 633 nm wavelength is 2200RIU–1 , 0.20 deg–1, 4.980 and 44.22 RIU–1 respectively. Silicon sheet is used in the middle of the Ag and platinum diselenide to prevent the oxidation of silver and enhance the sensitivity of platinum diselenide based surface plasmon resonance biosensor. The sensitivity of conventional surface plasmon resonance biosensor and the proposed surface plasmon resonance biosensor without silicon layer is 1700RIU–1 and 2000RIU–1 respectively. Surface plasmon resonance biosensor of device structure CaF2/Ag/Si/PtSe2 has higher sensitivity in comparison to device structures CaF2/Ag (conventional) and CaF2/Ag/PtSe2 (without Silicon Layer) by 29.41% and 10% respectively. Although the highest sensitivity obtained is 2620RIU–1 for 60 nm silver with 3 nm silicon layer except the platinum diselenide layer.
2004年石墨烯被发现后,二维材料以其独特的结构和非凡的性能引起了人们的广泛关注。二维过渡金属二硫族化合物在未来的纳米电子学中具有巨大的应用潜力,已成为研究的热点。过渡金属二硫族化合物具有可调的有限带隙和显著的过渡行为,非常适合于高性能电子和光电子器件的构建。而二硒化铂是一种单相自然发生的10族过渡金属二硫族化合物,理论上已被预测为一种优良的材料。提出了一种基于表面等离子体共振(SPR)的生物传感器结构,该结构由硅和二维纳米材料铂二硒化物组成。研究了基于表面等离子体共振的生物传感器的检测精度、优值、灵敏度、半最大值全宽度等性能参数。在633 nm波长下,银(50 nm)、硅(2 nm)和一层厚度为2 nm的二硒化铂表面等离子体共振生物传感器的灵敏度为2200RIU-1,检测精度为0.20°- 1,全宽半最大值为4.980,优值为44.22 RIU-1。银铂二硒化物中间采用硅片,防止银氧化,提高铂二硒化物基表面等离子体共振生物传感器的灵敏度。传统表面等离子体共振生物传感器和无硅层表面等离子体共振生物传感器的灵敏度分别为1700RIU-1和2000RIU-1。器件结构CaF2/Ag/Si/PtSe2的表面等离激元共振生物传感器的灵敏度比器件结构CaF2/Ag(常规)和CaF2/Ag/PtSe2(无硅层)分别提高了29.41%和10%。虽然除铂二硒化层外,对60 nm银和3 nm硅层获得的最高灵敏度为2620RIU-1。
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引用次数: 3
期刊
Sensor Letters
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