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Magnetic resonance imaging evaluation of the cerebellar tonsil position before and after posterior spinal fusion in adolescent idiopathic scoliosis. 青少年特发性脊柱侧弯症脊柱后路融合术前后小脑扁桃体位置的磁共振成像评估。
IF 1.6 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-25 DOI: 10.1007/s43390-024-00958-0
Bosio Santiago, Carolina Halliburton, Maenza Rubén, Puigdevall Miguel

Background: Chiari malformation type I(CM-I) is one of the most common neurological malformations observed in patients with adolescent idiopathic scoliosis (AIS). It remains uncertain whether AIS patients without neurological symptoms require CM-I decompression before undergoing spinal corrective surgery to prevent cerebellar tonsil herniation and potential neurological complications. This study aims to assess variations in the position of the cerebellar tonsil after posterior spinal fusion (PSF) in neurologically intact patients with AIS.

Methods: We retrospectively evaluated 40 patients with AIS who underwent posterior spinal fusion (PSF) without neurological symptoms. Sagittal hindbrain MRIs were performed before and after spinal surgery. The cerebellar tonsil's position relative to the foramen magnum was measured using the method described by Aboulezz (J Comput Assist Tomogr 1985). We assessed variations in the cerebellar tonsil position concerning spinal correction and elongation after PSF.

Results: The average preoperative magnitude of the scoliotic curve was 53.15 degrees (SD 10.46 degrees), and that of thoracic kyphosis was 35.42 degrees (SD 12.38 degrees). In the immediate postoperative period, the average magnitudes were 7.45 degrees (SD 7.33 degrees) and 27.87 degrees (SD 9.03 degrees), respectively. The average correction achieved with PSF was 86% in the coronal plane (p < 0.00001). The average length of the spine in the coronal plane was 44.5 cm (SD 5.25 cm) preoperatively and 48.27 cm (SD 4.40 cm) postoperatively (p < 0.00001). The average length of the vertebral column in the sagittal plane was 50.87 cm (SD 4.47 cm) preoperatively and 55.13 cm (SD 3.27 cm) postoperatively (p < 0.00001). No significant difference was observed in the position of the cerebellar tonsil in the measurements taken before and after spinal deformity correction (p = 0.6042). In 10 out of 40 patients, caudal displacement of the cerebellar tonsil was observed after PSF. In 28 patients, no variation in the position of the cerebellar tonsil was observed, and in 2, cephalic displacement was noted.

Conclusion: In AIS patients with a normal position of the cerebellar tonsil undergoing posterior spinal fusion, there is no significant change in their position after surgery. Our analysis did not reveal any correlation between curve correction, spine elongation, and variations in the cerebellar tonsil position.

Significance: The position of the cerebellar tonsil remained largely unchanged after PSF in AIS patients without neurological symptoms. Further studies would be necessary to determine whether surgical decompression is required in asymptomatic patients with CM-I before undergoing surgery to correct spinal deformity.

背景:Chiari畸形I型(CM-I)是青少年特发性脊柱侧凸(AIS)患者最常见的神经系统畸形之一。目前仍不确定无神经系统症状的AIS患者在接受脊柱矫正手术前是否需要对CM-I减压,以防止小脑扁桃体疝和潜在的神经系统并发症。本研究旨在评估神经功能完好的AIS患者接受脊柱后路融合术(PSF)后小脑扁桃体位置的变化:我们对40名接受脊柱后路融合术(PSF)且无神经症状的AIS患者进行了回顾性评估。脊柱手术前后均进行了后脑矢状位磁共振成像检查。使用 Aboulezz(J Comput Assist Tomogr 1985)描述的方法测量了小脑扁桃体相对于枕骨大孔的位置。我们评估了小脑扁桃体位置在 PSF 后与脊柱矫正和拉长有关的变化:结果:术前脊柱侧弯的平均幅度为 53.15 度(SD 10.46 度),胸椎后凸的平均幅度为 35.42 度(SD 12.38 度)。术后近期的平均幅度分别为 7.45 度(标准差为 7.33 度)和 27.87 度(标准差为 9.03 度)。PSF 在冠状面上的平均矫正率为 86%(P 结论:PSF 在冠状面上的平均矫正率为 86%:小脑扁桃体位置正常的 AIS 患者在接受脊柱后路融合术后,其位置没有明显变化。我们的分析并未发现曲线矫正、脊柱拉长与小脑扁桃体位置变化之间存在任何相关性:意义:对于无神经症状的 AIS 患者,PSF 术后小脑扁桃体的位置基本保持不变。有必要进行进一步研究,以确定无症状的 CM-I 患者在接受脊柱畸形矫正手术前是否需要手术减压。
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引用次数: 0
Outcome of distraction-based growing rods at graduation: a comparison of traditional growing rods and magnetically controlled growing rods. 分心式生长棒在毕业时的效果:传统生长棒与磁控生长棒的比较。
IF 1.6 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-23 DOI: 10.1007/s43390-024-00969-x
Jwalant Mehta, Suken Shah, Harry Hothi, Martina Tognini, Adrian Gardner, Charles E Johnston, Robert Murphy, George Thompson, Paul Sponseller, John Emans, Francisco Javier-Grueso, Peter Strum

Introduction: Distraction-based growing rods have been considered as an alternative surgical option for the operative treatment of EOS. TGR has been challenged by MCGR, which is reported to have the advantage of non-invasive lengthening with fewer planned returns to theatre. This study explores the radiographic outcomes, Unplanned Returns to the Operating Room (UPROR) and complication profile of both the procedures at the end of the planned growing rod treatment with either TGR or MCGR.

Methods: We included all the EOS cases from the PSSG database that underwent either TGR or MCGR with spine-based proximal anchors, followed up to the time of graduation. Any crossover or hybrid procedures were excluded. 549 patients (409 TGR and 140 MCGR) were eligible for review. We measured the coronal curve magnitude, Kyphosis, T1-T12, T1-S1 and L1-S1 lengths at 4 time points (before and after the index surgery and before and after the definitive surgery).

Results: The TGR group were slightly younger at the time of the index procedure (7 years for TGR vs. 8.5 years for MCGR, p < 0.001). We noted an improvement in all radiological parameters after the growing rod implantation. The spinal lengths increased through the lengthening period, while the coronal curve magnitude and the kyphosis increased. The kyphosis normalized following the final fusion, the coronal curve magnitude reduced further with a further increase in spinal lengths. The final follow-up from the time of the index implantation to the definitive surgery was 5.1 years (IQR 3.8) in TGR and 3.5 years (IQR 1.65) in the MCGR groups. The total number of complications was fewer in the MCGR group. The overall risk of UPROR was lower in the MCGR group and implant breakage was less in the MCGR group by 4.7 times.

Conclusions: This study confirms the equivalence of both the distraction-based growing rods systems from the radiological stand-point, during the lengthening phase and at the time of the definitive surgery. The TGR was more kyphogenic during the lengthening period. The complications and UPROR were fewer in the MCGR groups.

导言:牵引生长棒一直被认为是手术治疗 EOS 的替代手术方案。TGR受到了MCGR的挑战,据报道,MCGR具有非侵入性延长、计划返回手术室次数少的优点。本研究探讨了在使用 TGR 或 MCGR 的计划生长棒治疗结束后,两种手术的放射学结果、非计划重返手术室(UPROR)和并发症情况:我们纳入了PSSG数据库中所有使用脊柱近端锚进行TGR或MCGR的EOS病例,并随访至毕业。任何交叉或混合手术均排除在外。549例患者(409例TGR和140例MCGR)符合复查条件。我们测量了4个时间点(指数手术前后和最终手术前后)的冠状曲线幅度、后凸、T1-T12、T1-S1和L1-S1长度:结果:TGR组患者在进行指数手术时年龄稍小(TGR为7岁,MCGR为8.5岁,P 结论:该研究证实了TGR和MCGR两种手术方法的等效性:这项研究证实,从放射学角度来看,两种牵引生长棒系统在延长阶段和最终手术时的效果相当。在延长阶段,TGR的骺线更长。MCGR组的并发症和UPROR较少。
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引用次数: 0
Revisiting abdominal wall "morbidity" of the extensile anterolateral approach to the thoracolumbar spine. 重新审视胸腰椎前外侧延伸入路的腹壁 "发病率"。
IF 1.6 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-22 DOI: 10.1007/s43390-024-00971-3
Alekos A Theologis, Andrew P Collins, Kanwar Parhar, Munish C Gupta

Purpose: To assess patients' perceptions of their abdominal wall following extensile anterolateral approaches to the thoracolumbar spine for adult spinal deformity (ASD) using validated questionnaires.

Methods: Adults who underwent anterior-posterior thoracolumbar spinal operations to the pelvis for ASD in which the anterior fusion was performed through an extensile anterolateral approach were reviewed. Three questionnaires were administered at least 1 year following surgery and included The Abdominal Core Health Quality Collaborative Survey (AHS-QC), The Patient Scar Assessment Scale (PSAS), and The Anterior Abdominal Incision Questionnaire (AAIQ).

Results: Fifty-one patients (80.4% female, median age 65 years) were included. Average follow-up was 2.8 ± 1.7 years. Average number of anterior fusion levels was 3.5 ± 1.4. Patients achieved high satisfaction rates from surgery (74.5%). AAIQ responses included postoperative pain (33.3%), bulging (41.7%), and limitations in daily activities (18.8%) with only 15.7% experienced moderate-severe pain related to their incisions and only 6.3% seeking treatment for their scars. Post-operatively, 63.2% had a neutral or improved self-image of their torso and trunk, while only 10.2% stating it was much worse. Patients' overall opinion of their scar compared to their normal skin was very positive [average 2.75 ± 2.93 (10 = worst possible scar)]. Favorable scores were also reported for color difference, stiffness, change in thickness, and irregularity in their abdominal scar compared to normal skin.

Conclusions: Following extensile anterolateral approaches to the thoracolumbar spine for ASD, the majority of patients reported mild pain, mild functional limitations, good cosmesis, and high satisfaction rates with their anterior incisions based on validated questionnaires.

目的:使用经过验证的调查问卷,评估胸腰椎前外侧延伸入路治疗成人脊柱畸形(ASD)后患者对腹壁的看法:方法: 对因脊柱畸形(ASD)而接受胸腰椎前-后路骨盆手术的成人进行了回顾性研究,在这些手术中,前路融合是通过外展前外侧入路进行的。在术后至少一年进行了三次问卷调查,包括腹部核心健康质量合作调查(AHS-QC)、患者疤痕评估量表(PSAS)和腹部前切口问卷(AAIQ):共纳入 51 名患者(80.4% 为女性,中位年龄为 65 岁)。平均随访时间为 2.8 ± 1.7 年。前路融合的平均层数为 3.5 ± 1.4。患者对手术的满意度很高(74.5%)。AAIQ反应包括术后疼痛(33.3%)、隆起(41.7%)和日常活动受限(18.8%),只有15.7%的患者切口疼痛达到中度-重度,只有6.3%的患者寻求疤痕治疗。术后,63.2%的患者对躯干和躯干的自我形象持中性或改善态度,只有10.2%的患者表示躯干和躯干的自我形象大不如前。与正常皮肤相比,患者对其疤痕的总体评价非常正面[平均 2.75 ± 2.93(10 = 最糟糕的疤痕)]。与正常皮肤相比,患者对腹部疤痕的颜色差异、僵硬程度、厚度变化和不规则程度也给予了好评:根据有效的问卷调查,大多数患者在胸腰椎前外侧伸展入路治疗 ASD 后,疼痛轻微,功能受限程度轻微,外观良好,对前部切口的满意度较高。
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引用次数: 0
Current trends and perspectives of scoliosis research society travel fellows. 脊柱侧凸研究学会旅行研究员的当前趋势和展望。
IF 1.6 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-20 DOI: 10.1007/s43390-024-00962-4
Aditya Joshi, Arash Kamali, Jordan Helbing, Michelle C Welborn, Steven W Hwang, Amit Jain, Khaled Kebaish, Hamid Hassanzadeh

Purpose: This study aims to measure the impact of the Scoliosis Research Society's travel fellowship on a spinal surgeon's career.

Methods: A non-incentivized survey was sent to 78 previous SRS junior travel fellows from 1993 to 2021. The questionnaire assessed fellowship influence on academic and administrative positions, professional society memberships, and commercial relationships. The trend of these quantitative measures was created according to a compounded annual growth rate (CAGR) calculation of the reported values. The Scopus database was queried for all fellows' publication counts and h-index before the fellowship, as well as 3 years, 5 years, and currently after the fellowship. A control cohort of matched surgeons who did not participate in travel fellowships was used to compare research productivity measures relative to travel fellows.

Results: This study had a 73% response rate. Over the periods of 3-5 years after the fellowship, and up to the present, the mean publication count increased by 31.0%, 31.6%, and 46.4%, respectively. Over the same interval, the mean h-index increased by 19.5%, 17.3%, and 11.3%, respectively. From the year of their respective fellowship to present day, the fellows observed a mean CAGR of + 3.2% in academic positions, + 6.7% in administrative positions, + 2.3% in society memberships, and + 4.7% in commercial relations. Previous fellows concurred the fellowship changed their clinical practice (42.1% Strongly Agree, 36.8% Agree), expanded their network (71.9% Strong Agree, 24.6% Agree), expanded their research (33.3% Strongly Agree, 54.4% Agree), and improved their surgical technique (33.3% Strongly Agree, 49.1% Agree).

Conclusion: Robust feedback from previous fellows suggests a traveling fellowship has a meaningful impact on a surgeon's research productivity and career achievements.

目的:本研究旨在衡量脊柱侧弯研究学会旅行奖学金对脊柱外科医生职业生涯的影响:我们向1993年至2021年期间的78名脊柱侧弯研究学会初级旅行奖学金获得者进行了非激励性调查。问卷评估了研究金对学术和行政职位、专业协会会员资格以及商业关系的影响。这些量化指标的趋势是根据报告值的复合年增长率 (CAGR) 计算得出的。我们在 Scopus 数据库中查询了所有研究员在获得研究金之前、获得研究金之后 3 年、5 年和目前的发表论文数量和 h 指数。研究人员还利用未参加旅行研究金的外科医生作为对照组,比较他们与旅行研究金获得者的研究生产率:本研究的回复率为 73%。在研究金结束后的 3-5 年间,直到现在,平均发表论文数量分别增加了 31.0%、31.6% 和 46.4%。在同一时期,平均 h 指数分别增加了 19.5%、17.3% 和 11.3%。从获得研究金的那一年至今,研究员们在学术职位上的平均年复合增长率为 + 3.2%,在行政职位上的平均年复合增长率为 + 6.7%,在学会会员资格上的平均年复合增长率为 + 2.3%,在商业关系上的平均年复合增长率为 + 4.7%。往届学员一致认为,研究金改变了他们的临床实践(42.1% 强烈同意,36.8% 同意),扩大了他们的人际网络(71.9% 强烈同意,24.6% 同意),拓展了他们的研究(33.3% 强烈同意,54.4% 同意),并提高了他们的手术技巧(33.3% 强烈同意,49.1% 同意):来自历届研究员的大量反馈表明,巡回研究金对外科医生的研究效率和职业成就有着重要影响。
{"title":"Current trends and perspectives of scoliosis research society travel fellows.","authors":"Aditya Joshi, Arash Kamali, Jordan Helbing, Michelle C Welborn, Steven W Hwang, Amit Jain, Khaled Kebaish, Hamid Hassanzadeh","doi":"10.1007/s43390-024-00962-4","DOIUrl":"https://doi.org/10.1007/s43390-024-00962-4","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to measure the impact of the Scoliosis Research Society's travel fellowship on a spinal surgeon's career.</p><p><strong>Methods: </strong>A non-incentivized survey was sent to 78 previous SRS junior travel fellows from 1993 to 2021. The questionnaire assessed fellowship influence on academic and administrative positions, professional society memberships, and commercial relationships. The trend of these quantitative measures was created according to a compounded annual growth rate (CAGR) calculation of the reported values. The Scopus database was queried for all fellows' publication counts and h-index before the fellowship, as well as 3 years, 5 years, and currently after the fellowship. A control cohort of matched surgeons who did not participate in travel fellowships was used to compare research productivity measures relative to travel fellows.</p><p><strong>Results: </strong>This study had a 73% response rate. Over the periods of 3-5 years after the fellowship, and up to the present, the mean publication count increased by 31.0%, 31.6%, and 46.4%, respectively. Over the same interval, the mean h-index increased by 19.5%, 17.3%, and 11.3%, respectively. From the year of their respective fellowship to present day, the fellows observed a mean CAGR of + 3.2% in academic positions, + 6.7% in administrative positions, + 2.3% in society memberships, and + 4.7% in commercial relations. Previous fellows concurred the fellowship changed their clinical practice (42.1% Strongly Agree, 36.8% Agree), expanded their network (71.9% Strong Agree, 24.6% Agree), expanded their research (33.3% Strongly Agree, 54.4% Agree), and improved their surgical technique (33.3% Strongly Agree, 49.1% Agree).</p><p><strong>Conclusion: </strong>Robust feedback from previous fellows suggests a traveling fellowship has a meaningful impact on a surgeon's research productivity and career achievements.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rule breakers achieve successful shoulder balance: unraveling the myth of upper instrumented vertebrae selection criteria. 打破常规者成功实现肩关节平衡:揭开上部器械椎体选择标准的神秘面纱。
IF 1.6 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-20 DOI: 10.1007/s43390-024-00961-5
Luke C Drake, Peter W D'Amore, Bailli Fontenot, Tyler A Tetreault, Manaf Younis, Claudia Leonardi, Jaquelyn Valenzuela-Moss, Lindsay M Andras, Michael J Heffernan

Purpose: This study compared shoulder balance outcomes in "rule breakers" (RB) vs. "rule followers" (RF) based on commonly utilized upper instrumented vertebrae (UIV) selection guidelines.

Methods: Adolescent idiopathic scoliosis (AIS) patients (Lenke 1-4) who underwent posterior spine fusion (PSF) with minimum 2-year follow-up had radiographic measurement of shoulder balance including first rib angle (FRA), T1 tilt, coracoid process height difference (CPHD), and clavicle angle (CA) at preop, postop, 6-month, 1-year, and 2-year timepoints. Postoperative outcomes were compared between RB and RF groups defined based on the UIV selection guidelines of Rose and Lenke.

Results: Among 88 patients (43 RF, 45 RB), age, gender, preoperative T1 tilt, FRA, CA, and CPHD were not significantly different between groups (p > 0.05). Immediately post-surgery, the RF group had more balanced shoulders (CPHD: 11.6 mm vs. 15.7 mm, p = 0.033; CA: 2.8° vs. 3.6°, p = 0.045; FRA: 3.4° vs. 5.1°, p = 0.009; T1 tilt: 4.7° vs. 6.1°, p = 0.045). At 2 years, no difference was observed between RF vs. RB in CA (2.3 vs. 2.2°, p = 0.857) and CPHD (8.5 vs. 8.1 mm, p = 0.791). FRA and T1 tilt were higher in RB vs. RF (FRA: 4.6 vs. 2.9°, p = 0.002; T1 tilt: 5.6 vs. 3.9, p = 0.008). Shoulder balance (CPHD < 1 cm) was achieved in 73.1% of RB and 69.9% of RF at 2-year follow-up (p = 0.216).

Conclusion: Adherence to commonly accepted UIV selection guidelines did not predict better shoulder balance. The RB group had worse shoulder balance immediately post-surgery, but also improved more over time. These results suggest the need to refine current UIV selection and management.

Level of evidence: III.

目的:本研究根据常用的上部器械椎体(UIV)选择指南,比较了 "规则打破者"(RB)与 "规则遵循者"(RF)的肩部平衡结果:青少年特发性脊柱侧凸(AIS)患者(Lenke 1-4)接受了脊柱后路融合术(PSF),随访至少2年,在术前、术后、6个月、1年和2年的时间点进行了肩部平衡的影像学测量,包括第一肋角(FRA)、T1倾斜度、冠突高度差(CPHD)和锁骨角(CA)。根据Rose和Lenke的UIV选择指南,比较了RB组和RF组的术后效果:在 88 位患者中(43 位 RF,45 位 RB),年龄、性别、术前 T1 倾斜、FRA、CA 和 CPHD 在组间无明显差异(P > 0.05)。手术后,RF 组的肩部更平衡(CPHD:11.6 mm vs. 15.7 mm,p = 0.033;CA:2.8° vs. 3.6°,p = 0.045;FRA:3.4° vs. 5.1°,p = 0.009;T1 倾斜:4.7° vs. 6.1°,p = 0.045)。2年后,RF与RB在CA(2.3 vs. 2.2°,p = 0.857)和CPHD(8.5 vs. 8.1 mm,p = 0.791)方面没有差异。RB与RF相比,FRA和T1倾斜度更高(FRA:4.6 vs. 2.9°,p = 0.002;T1倾斜度:5.6 vs. 3.9,p = 0.008)。肩部平衡(CPHD 结论:遵守普遍接受的 UIV 选择指南并不能预示肩部平衡的改善。RB组术后肩部平衡能力较差,但随着时间的推移也会得到改善。这些结果表明有必要改进目前的 UIV 选择和管理:证据等级:III。
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引用次数: 0
Accuracy of screw placement during vertebral body tethering using fluoroscopic guidance and anatomic landmarks. 使用透视引导和解剖标志在椎体系带术中准确放置螺钉。
IF 1.6 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-18 DOI: 10.1007/s43390-024-00970-4
Kevin M Neal, Kylie Krombholz, Mona Doshi

Purpose: To determine the accuracy of screw placement using fluoroscopy and anatomic landmarks during vertebral body tethering (VBT) surgery.

Methods: Ten patients with 73 VBT screws were converted to posterior spinal fusion (PSF) after continued curve progression. The positions of each VBT screw were analyzed using intraoperative computed tomography (CT) scans performed for image guidance during VBT. Differences for screws placed using an open versus thoracoscopic approach were noted for the screw position in each vertebra, distance from the spinal canal, unicortical versus bicortical placement, the distance of screw tips from the thoracic aorta, and impingement of screws on adjacent rib heads.

Results: Seventy three (73) screws in ten (10) patients were available for analysis. Only 21% of screws were placed traversing the middle one-third of the vertebral body, without spinal canal penetration, with the distal tip placed unicortically or bicortically as planned, and without touching the thoracic aorta. The rates of non-ideal screw placement were not significantly different for screws placed via thoracoscopic versus open approaches. Five (5) screws (6.8%) penetrated the spinal canal 1-2 mm, but without known clinical sequelae.

Conclusion: The majority of VBT screws available for analysis were placed in non-ideal positions, suggesting that accurate screw placement using intraoperative fluoroscopy and anatomic landmarks can be challenging, but without adverse clinical consequences.

目的:确定在椎体拴系(VBT)手术中使用透视和解剖标志放置螺钉的准确性:方法:10 名患者共使用了 73 颗 VBT 螺钉,在脊柱曲线继续发展后转为后路脊柱融合术(PSF)。我们使用术中计算机断层扫描(CT)分析了每颗 VBT 螺钉的位置,CT 扫描用于 VBT 期间的图像引导。结果显示,采用开放式方法与胸腔镜方法放置的螺钉在每个椎体的位置、与椎管的距离、单皮质与双皮质放置、螺钉尖端与胸主动脉的距离以及螺钉与邻近肋骨头的撞击等方面存在差异:共有十(10)名患者的 73 颗螺钉可供分析。只有 21% 的螺钉穿过了椎体的中间三分之一,没有穿透椎管,远端按计划置于单皮质或双皮质,并且没有触及胸主动脉。通过胸腔镜和开放式方法放置螺钉的非理想螺钉放置率没有明显差异。五(5)枚螺钉(6.8%)穿透椎管 1-2 毫米,但没有已知的临床后遗症:结论:大多数可用于分析的 VBT 螺钉都放置在非理想位置,这表明使用术中透视和解剖标志准确放置螺钉具有挑战性,但不会产生不良临床后果。
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引用次数: 0
Optimizing sacral screw fixation in patients with caudal regression syndrome. 优化尾椎退缩综合征患者的骶骨螺钉固定。
IF 1.6 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-16 DOI: 10.1007/s43390-024-00968-y
Olga M Sergeenko, Dmitry M Savin, Anastacia Gabrielyan, Yulia S Arestova, Sergey O Ryabykh, Alexander V Burtsev, Alexey V Evsyukov

Purpose: The aim of this study is to evaluate and compare techniques and outcomes associated with two different technique of pelvic screw insertion in patients with caudal spine absence.

Methods: A cohort of patients with varying degrees of caudal structural regression, serves as the focal point of this investigation. Pelvic configurations were classified based on established criteria to facilitate comparative analysis. Each patient underwent spinal surgical interventions, with a follow-up period extending beyond 2 years. The primary surgical interventions predominantly involved spinal stabilization coupled with correction of scoliosis and kyphosis through one or two pairs of pelvic screws.

Results: In this study, we investigated a cohort of 22 patients with caudal spine absence, encompassing diverse conditions, such as lumbo-sacral aplasia, hemisacrum, and lumbar absence, with preserved sacrum. Following spinal surgery, notable improvements were observed in scoliosis and pathological lumbar kyphosis, with several patients achieving significant functional milestones such as independent ambulation. There were no significant differences in short-term complications between patients undergoing single versus double pair pelvic screw implantation. Long-term complications, primarily non-fusion, were notably more prevalent in patients undergoing fixation with a single pair of pelvic screws.

Conclusion: Surgical intervention, particularly spinopelvic fixation, demonstrated promising outcomes in terms of improving spinal deformities. The implantation of two pairs of pelvic screws demonstrates greater reliability compared to the insertion of a single pair, diminishing the risk of non-fusion.

目的:本研究旨在评估和比较两种不同的骨盆螺钉植入技术在尾椎缺失患者中的应用效果:方法:本研究的重点是一组具有不同程度尾椎结构退变的患者。骨盆结构根据既定标准进行分类,以便进行比较分析。每位患者都接受了脊柱手术干预,随访时间超过两年。主要的手术治疗主要是通过一对或两对骨盆螺钉来稳定脊柱并矫正脊柱侧弯和后凸:在这项研究中,我们对22名尾椎缺失患者进行了调查,这些患者的病症多种多样,如隆骶骨发育不良、半骶骨发育不良和腰椎缺失,但保留了骶骨。脊柱手术后,脊柱侧弯和病理性腰椎畸形得到明显改善,多名患者达到了独立行走等重要功能里程碑。接受单对骨盆螺钉植入术和双对骨盆螺钉植入术的患者在短期并发症方面没有明显差异。使用单对骨盆螺钉固定的患者出现长期并发症(主要是不融合)的比例明显更高:结论:手术干预,尤其是脊柱骨盆固定术,在改善脊柱畸形方面显示出良好的效果。与植入一对骨盆螺钉相比,植入两对骨盆螺钉的可靠性更高,从而降低了不融合的风险。
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引用次数: 0
Spinal deformity surgery in Scheuermann's kyphosis versus adolescent idiopathic scoliosis: meta-analysis of complications and clinical outcomes. 舍曼氏脊柱后凸与青少年特发性脊柱侧凸的脊柱畸形手术:并发症和临床结果的荟萃分析。
IF 1.6 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-16 DOI: 10.1007/s43390-024-00967-z
Mohammad Daher, Rhea Rasquinha, Manjot Singh, Joseph E Nassar, Chibuokem P Ikwuazom, Bassel G Diebo, Alan H Daniels

Background: Surgical management of adolescent idiopathic scoliosis (AIS) and Scheuermann's kyphosis (SK) may be associated with several complications including extended length of stay and unplanned reoperations. Several studies have previously compared postoperative complications and functional outcomes for AIS and SK patients with mixed results. However, a meta-analysis compiling the literature on this topic is lacking.

Methods: Following the PRISMA guidelines, PubMed, Cochrane, and Google Scholar (pages 1-20) were accessed and explored until April 2024. The extracted data consisted of complications (overall and surgical-site infections [SSI]), readmissions, reoperations, and Scoliosis Research Society-22 (SRS-22) score. Mean differences (MD) with 95% CI were used for continuous data and odds ratio (OR) was utilized for dichotomous data were calculated across studies.

Results: Seven retrospective articles were included in the meta-analysis, including 4866 patients, with 399 in the SK group and 4467 in the AIS group. SK patients were found to have statistically significantly higher rates of overall complications (OR = 5.41; 95% CI 3.69-7.93, p < .001), SSI (OR = 11.30; 95% CI 6.14-20.82, p < .001), readmissions (OR = 2.81; 95% CI 1.21-6.53, p = 0.02), and reoperations (OR = 7.40; 95% CI 4.76-11.51, p < .001) than AIS patients. However, they had similar SRS-22 scores postoperatively (MD = -0.06; 95% CI -0.16 to 0.04, p = 0.26) despite the SK group having lower SRS-22 scores preoperatively (MD = -0.30; 95% CI -0.42 to -0.18, p < .001).

Conclusion: In this meta-analysis of studies comparing spinal deformity surgery outcomes in AIS and SK patients, SK was associated with more complications, readmissions, and reoperations. SK did have equivalent SRS-22 scores postoperatively to AIS patients, highlighting the benefit of surgical treatment despite higher complication rates. This data may help inform healthcare institutions, payors, and quality monitoring organizations who examine outcomes of pediatric and adult spinal deformity surgery.

背景:青少年特发性脊柱侧弯(AIS)和谢尔曼氏脊柱侧弯(SK)的手术治疗可能会引起多种并发症,包括住院时间延长和意外再次手术。之前有几项研究比较了 AIS 和 SK 患者的术后并发症和功能预后,结果不一。然而,目前还缺乏对相关文献的荟萃分析:按照 PRISMA 指南,访问并研究了 PubMed、Cochrane 和 Google Scholar(第 1-20 页),直至 2024 年 4 月。提取的数据包括并发症(总并发症和手术部位感染 [SSI])、再入院率、再手术率和脊柱侧凸研究学会-22(SRS-22)评分。连续性数据采用平均差(MD)和 95% CI,二分法数据采用几率比(OR):荟萃分析纳入了七篇回顾性文章,包括 4866 例患者,其中 SK 组 399 例,AIS 组 4467 例。结果发现,SK 组患者的总体并发症发生率明显更高(OR = 5.41;95% CI 3.69-7.93,P 结论:SK 组患者的并发症发生率明显高于 AIS 组:在这项比较 AIS 和 SK 患者脊柱畸形手术结果的荟萃分析研究中,SK 与更多并发症、再入院和再手术有关。SK患者术后的SRS-22评分与AIS患者相当,这说明尽管并发症发生率较高,但手术治疗仍有益处。这些数据可能有助于为医疗机构、付款人和质量监测机构提供信息,帮助他们检查儿童和成人脊柱畸形手术的结果。
{"title":"Spinal deformity surgery in Scheuermann's kyphosis versus adolescent idiopathic scoliosis: meta-analysis of complications and clinical outcomes.","authors":"Mohammad Daher, Rhea Rasquinha, Manjot Singh, Joseph E Nassar, Chibuokem P Ikwuazom, Bassel G Diebo, Alan H Daniels","doi":"10.1007/s43390-024-00967-z","DOIUrl":"https://doi.org/10.1007/s43390-024-00967-z","url":null,"abstract":"<p><strong>Background: </strong>Surgical management of adolescent idiopathic scoliosis (AIS) and Scheuermann's kyphosis (SK) may be associated with several complications including extended length of stay and unplanned reoperations. Several studies have previously compared postoperative complications and functional outcomes for AIS and SK patients with mixed results. However, a meta-analysis compiling the literature on this topic is lacking.</p><p><strong>Methods: </strong>Following the PRISMA guidelines, PubMed, Cochrane, and Google Scholar (pages 1-20) were accessed and explored until April 2024. The extracted data consisted of complications (overall and surgical-site infections [SSI]), readmissions, reoperations, and Scoliosis Research Society-22 (SRS-22) score. Mean differences (MD) with 95% CI were used for continuous data and odds ratio (OR) was utilized for dichotomous data were calculated across studies.</p><p><strong>Results: </strong>Seven retrospective articles were included in the meta-analysis, including 4866 patients, with 399 in the SK group and 4467 in the AIS group. SK patients were found to have statistically significantly higher rates of overall complications (OR = 5.41; 95% CI 3.69-7.93, p < .001), SSI (OR = 11.30; 95% CI 6.14-20.82, p < .001), readmissions (OR = 2.81; 95% CI 1.21-6.53, p = 0.02), and reoperations (OR = 7.40; 95% CI 4.76-11.51, p < .001) than AIS patients. However, they had similar SRS-22 scores postoperatively (MD = -0.06; 95% CI -0.16 to 0.04, p = 0.26) despite the SK group having lower SRS-22 scores preoperatively (MD = -0.30; 95% CI -0.42 to -0.18, p < .001).</p><p><strong>Conclusion: </strong>In this meta-analysis of studies comparing spinal deformity surgery outcomes in AIS and SK patients, SK was associated with more complications, readmissions, and reoperations. SK did have equivalent SRS-22 scores postoperatively to AIS patients, highlighting the benefit of surgical treatment despite higher complication rates. This data may help inform healthcare institutions, payors, and quality monitoring organizations who examine outcomes of pediatric and adult spinal deformity surgery.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoperative fluid management in adult spinal deformity surgery: variation analysis and association with outcomes. 成人脊柱畸形手术的术中液体管理:变异分析及与预后的关系。
IF 1.6 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-12 DOI: 10.1007/s43390-024-00966-0
Riza M Cetik, Jeffrey L Gum, Renaud Lafage, Justin S Smith, Shay Bess, Jeffrey P Mullin, Michael P Kelly, Bassel G Diebo, Thomas J Buell, Justin K Scheer, Breton G Line, Virginie Lafage, Eric O Klineberg, Han Jo Kim, Peter G Passias, Khaled M Kebaish, Robert K Eastlack, Alan H Daniels, Alex Soroceanu, Gregory M Mundis, Richard A Hostin, Themistocles S Protopsaltis, D Kojo Hamilton, Robert A Hart, Munish C Gupta, Stephen J Lewis, Frank J Schwab, Lawrence G Lenke, Christopher I Shaffrey, Christopher P Ames, Douglas C Burton

Purpose: To evaluate the variability in intraoperative fluid management during adult spinal deformity (ASD) surgery, and analyze the association with complications, intensive care unit (ICU) requirement, and length of hospital stay (LOS).

Methods: Multicenter comparative cohort study. Patients ≥ 18 years old and with ASD were included. Intraoperative intravenous (IV) fluid data were collected including: crystalloids, colloids, crystalloid/colloid ratio (C/C), total IV fluid (tIVF, ml), normalized total IV fluid (nIVF, ml/kg/h), input/output ratio (IOR), input-output difference (IOD), and normalized input-output difference (nIOD, ml/kg/h). Data from different centers were compared for variability analysis, and fluid parameters were analyzed for possible associations with the outcomes.

Results: Seven hundred ninety-eight patients with a median age of 65.2 were included. Among different surgical centers, tIVF, nIVF, and C/C showed significant variation (p < 0.001 for each) with differences of 4.8-fold, 3.7-fold, and 4.9-fold, respectively. Two hundred ninety-two (36.6%) patients experienced at least one in-hospital complication, and ninety-two (11.5%) were IV fluid related. Univariate analysis showed significant relations for: LOS and tIVF (ρ = 0.221, p < 0.001), IOD (ρ = 0.115, p = 0.001) and IOR (ρ = -0.138, p < 0.001); IV fluid-related complications and tIVF (p = 0.049); ICU stay and tIVF, nIVF, IOD and nIOD (p < 0.001 each); extended ICU stay and tIVF (p < 0.001), nIVF (p = 0.010) and IOD (p < 0.001). Multivariate analysis controlling for confounders showed significant relations for: LOS and tIVF (p < 0.001) and nIVF (p = 0.003); ICU stay and IOR (p = 0.002), extended ICU stay and tIVF (p = 0.004).

Conclusion: Significant variability and lack of standardization in intraoperative IV fluid management exists between different surgical centers. Excessive fluid administration was found to be correlated with negative outcomes.

Level of evidence: III.

目的:评估成人脊柱畸形(ASD)手术中术中液体管理的变化,分析其与并发症、重症监护室(ICU)需求和住院时间(LOS)的关系:多中心比较队列研究。方法:多中心比较队列研究,纳入年龄≥ 18 岁的 ASD 患者。收集的术中静脉输液数据包括:晶体液、胶体液、晶体液/胶体液比率(C/C)、静脉输液总量(tIVF,毫升)、归一化静脉输液总量(nIVF,毫升/千克/小时)、输入输出比率(IOR)、输入输出差值(IOD)和归一化输入输出差值(nIOD,毫升/千克/小时)。对来自不同中心的数据进行了变异性分析比较,并分析了体液参数与结果之间可能存在的关联:共纳入 798 名患者,中位年龄为 65.2 岁。在不同的手术中心,tIVF、nIVF 和 C/C 显示出显著的差异(p 结论:在不同的手术中心,tIVF、nIVF 和 C/C 显示出显著的差异:不同手术中心在术中静脉输液管理方面存在显著差异且缺乏标准化。过度输液与不良结果相关:证据等级:III。
{"title":"Intraoperative fluid management in adult spinal deformity surgery: variation analysis and association with outcomes.","authors":"Riza M Cetik, Jeffrey L Gum, Renaud Lafage, Justin S Smith, Shay Bess, Jeffrey P Mullin, Michael P Kelly, Bassel G Diebo, Thomas J Buell, Justin K Scheer, Breton G Line, Virginie Lafage, Eric O Klineberg, Han Jo Kim, Peter G Passias, Khaled M Kebaish, Robert K Eastlack, Alan H Daniels, Alex Soroceanu, Gregory M Mundis, Richard A Hostin, Themistocles S Protopsaltis, D Kojo Hamilton, Robert A Hart, Munish C Gupta, Stephen J Lewis, Frank J Schwab, Lawrence G Lenke, Christopher I Shaffrey, Christopher P Ames, Douglas C Burton","doi":"10.1007/s43390-024-00966-0","DOIUrl":"https://doi.org/10.1007/s43390-024-00966-0","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the variability in intraoperative fluid management during adult spinal deformity (ASD) surgery, and analyze the association with complications, intensive care unit (ICU) requirement, and length of hospital stay (LOS).</p><p><strong>Methods: </strong>Multicenter comparative cohort study. Patients ≥ 18 years old and with ASD were included. Intraoperative intravenous (IV) fluid data were collected including: crystalloids, colloids, crystalloid/colloid ratio (C/C), total IV fluid (tIVF, ml), normalized total IV fluid (nIVF, ml/kg/h), input/output ratio (IOR), input-output difference (IOD), and normalized input-output difference (nIOD, ml/kg/h). Data from different centers were compared for variability analysis, and fluid parameters were analyzed for possible associations with the outcomes.</p><p><strong>Results: </strong>Seven hundred ninety-eight patients with a median age of 65.2 were included. Among different surgical centers, tIVF, nIVF, and C/C showed significant variation (p < 0.001 for each) with differences of 4.8-fold, 3.7-fold, and 4.9-fold, respectively. Two hundred ninety-two (36.6%) patients experienced at least one in-hospital complication, and ninety-two (11.5%) were IV fluid related. Univariate analysis showed significant relations for: LOS and tIVF (ρ = 0.221, p < 0.001), IOD (ρ = 0.115, p = 0.001) and IOR (ρ = -0.138, p < 0.001); IV fluid-related complications and tIVF (p = 0.049); ICU stay and tIVF, nIVF, IOD and nIOD (p < 0.001 each); extended ICU stay and tIVF (p < 0.001), nIVF (p = 0.010) and IOD (p < 0.001). Multivariate analysis controlling for confounders showed significant relations for: LOS and tIVF (p < 0.001) and nIVF (p = 0.003); ICU stay and IOR (p = 0.002), extended ICU stay and tIVF (p = 0.004).</p><p><strong>Conclusion: </strong>Significant variability and lack of standardization in intraoperative IV fluid management exists between different surgical centers. Excessive fluid administration was found to be correlated with negative outcomes.</p><p><strong>Level of evidence: </strong>III.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Goldenhar syndrome associated with increased risk of respiratory failure and reoperations following spinal deformity surgery. 戈登哈尔综合征与脊柱畸形手术后呼吸衰竭和再次手术风险增加有关。
IF 1.6 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-09 DOI: 10.1007/s43390-024-00963-3
Michael J Gouzoulis, Sahir S Jabbouri, Anthony E Seddio, Jonathan N Grauer, Dominick A Tuason

Background: Goldenhar syndrome is a rare congenital disease that presents with a spectrum of clinical sequelae related to the vertebrae and other organs. The spinal manifestations of the syndrome are associated with scoliosis for which fusion may be considered. The current study aimed to evaluate the risks of adverse events and reoperations following posterior spinal fusion for those with Goldenhar syndrome relative to those with adolescent idiopathic scoliosis (AIS).

Methods: Patients with Goldenhar syndrome and AIS between the ages of 10 and 17 who underwent posterior spinal fusion were abstracted from the 2010 to 2022 PearlDiver Database. The Goldenhar syndrome patients were matched 1:4 to patients with AIS based on age, sex, and Elixhauser Comorbidity Index. All 90 day postoperative adverse events, readmissions, and 5 year reoperations were identified using administrative coding. Incidence of adverse events between the cohorts were compared using multivariate logistic regression.

Results: A total of 11,742 patients with AIS and 72 (0.61%) Goldenhar syndrome undergoing deformity surgery were identified. On matched comparison, patients with Goldenhar syndromes had higher odds ratio (OR) of respiratory failure (OR: 2.99, p = 0.009), severe adverse events (p = 2.29, p = 0.01), and readmissions (p = 2.26, p = 0.02). Over 5 years, they had a significantly higher incidence of reoperation compared to those with AIS (18.1% versus 5.5%, p = 0.005).

Conclusions: In this national sample of patients with Goldenhar syndrome undergoing posterior spinal fusion, patients with Goldenhar had increased odds of respiratory failure, readmissions, and reoperations. Targeted risk mitigation strategies may be appropriately considered for those with Goldenhar syndrome undergoing such surgeries.

Level of evidence: Level III; Case-control study or retrospective cohort study.

背景:戈登哈尔综合征是一种罕见的先天性疾病,会出现一系列与脊椎和其他器官有关的临床后遗症。该综合征的脊柱表现与脊柱侧弯有关,可考虑行脊柱融合术。本研究旨在评估戈登哈尔综合征患者与青少年特发性脊柱侧弯症(AIS)患者后路脊柱融合术后发生不良事件和再次手术的风险:从2010年至2022年的PearlDiver数据库中抽取了10岁至17岁接受脊柱后路融合术的戈登哈尔综合征和AIS患者。根据年龄、性别和Elixhauser合并症指数,将Goldenhar综合征患者与AIS患者进行1:4配对。所有术后 90 天不良事件、再入院和 5 年再手术均通过行政编码确定。使用多变量逻辑回归比较了不同组群之间的不良事件发生率:共有 11,742 名 AIS 患者和 72 名(0.61%)接受畸形手术的戈登哈尔综合征患者。经匹配比较,戈登哈尔综合征患者发生呼吸衰竭(OR:2.99,P = 0.009)、严重不良事件(P = 2.29,P = 0.01)和再住院(P = 2.26,P = 0.02)的几率比(OR)更高。5年内,他们再次手术的发生率明显高于AIS患者(18.1%对5.5%,p = 0.005):结论:在对接受后路脊柱融合术的戈登哈尔综合征患者进行的全国抽样调查中,戈登哈尔患者发生呼吸衰竭、再入院和再次手术的几率增加。对于接受此类手术的戈登哈尔综合征患者,可适当考虑采取有针对性的风险缓解策略:证据等级:III级;病例对照研究或回顾性队列研究。
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引用次数: 0
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