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2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)最新文献

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Fragrance allergens — Possibilities of their identification in components of cosmetotextiles 香氛过敏原。化妆品纺织品成分中香氛过敏原鉴别的可能性
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533711
E. Adamowicz, M. Sikora, Radosław Bonikowski, M. Frydrysiak
Fragrances and essential oils are often microencapsulated and applied on textiles designed for elders, both as compounds of cosmetics and as fragrances e.g. in aromatherapy. However in the aromatic compositions there may be compounds with allergenic activity. Possibility of identification potential fragrance allergens which may be applied on textiles in microcapsules is presented in this article.
香水和精油通常被微胶囊化并应用于为老年人设计的纺织品上,既可以作为化妆品的化合物,也可以作为芳香剂,例如芳香疗法。然而,在芳香组合物中可能存在具有致敏活性的化合物。介绍了微胶囊纺织品中潜在香氛过敏原的鉴别方法。
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引用次数: 0
Experimental validation of MWA effects on biological tissue by sensorized needles based on FBG technology 基于光纤光栅技术的传感针对生物组织MWA效应的实验验证
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533804
Serena Villani, P. Saccomandi, C. Massaroni, E. Schena, R. Cazzato, F. Giurazza, G. Frauenfelder
The aim of the present study was to simulate and experimental assess the temperature distribution and damaged tissue in ex vivo porcine livers undergoing microwave ablation (MWA). Firstly, the interaction between microwave (MW) and liver was simulated to predict tissue temperature distribution and damaged volume; then numerical simulations were experimentally validated. Simulations were performed: i) by considering the geometry of the MW antenna used during the experiments, ii) by implementing the Pennes' equation to calculate the temperature map within the tissue, and iii) by using Arrhenius model to calculate the damaged tissue. The model was validated by performing experiments on four ex vivo pig livers, which were treated using a 2.45 GHz antenna at 100 W for 4 min. Three custom probes were fabricated and calibrated to measure tissue temperature during MWA. These probes consist of a needle embedding one or more Fiber Bragg grating (FBG) sensors. The three probes embed a total of eight FBGs, hence tissue temperature during MWA was monitored at eight distances from the antenna. Simulated temperatures around the antenna agree with experimental data. Moreover, the predicted damaged volume agrees with the volume of coagulation experienced by the tissue undergoing MWA. In conclusion, the proposed thermometric probes allow performing distributed temperature measurement during MWA, as well as facilitate the insertion of the FBGs within the organ. The measurements show that the model is able to accurately predict MWA effects in an ex vivo pig liver.
本研究的目的是模拟和实验评估离体猪肝脏在微波消融(MWA)过程中的温度分布和损伤组织。首先,模拟微波与肝脏的相互作用,预测组织温度分布和损伤体积;然后进行了数值模拟实验验证。分别考虑实验中使用的毫瓦天线的几何形状,利用Pennes方程计算组织内的温度分布图,利用Arrhenius模型计算损伤组织。该模型通过在4个离体猪肝上进行实验来验证,这些猪肝使用2.45 GHz天线在100 W下处理4分钟。制作并校准了三个定制探针来测量MWA期间的组织温度。这些探头由嵌入一个或多个光纤布拉格光栅(FBG)传感器的针组成。这三个探针共嵌入了8个fbg,因此在距离天线8个距离处监测MWA期间的组织温度。天线周围的模拟温度与实验数据吻合。此外,预测的损伤体积与接受MWA的组织所经历的凝血体积一致。总之,所提出的测温探头允许在MWA期间进行分布式温度测量,并促进fbg在器官内的插入。实验结果表明,该模型能够准确预测MWA在离体猪肝中的作用。
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引用次数: 1
An architecture for health data collection using off-the-shelf health sensors 使用现成的健康传感器收集健康数据的架构
Pub Date : 2016-05-15 DOI: 10.1109/MEMEA.2016.7533815
Roozbeh Jalali, A. Dauda, K. El-Khatib, C. McGregor, Chirag Surti
Nowadays, many people, and not only the ones with health problems are being more health conscious. With the advent of sensor based technologies, it has become possible to create wearable wireless biometric sensor networks, known as Body Sensor Networks (BSNs) which allow people to collect their health data and send it remotely for further analysis and storage. Research has shown that the use of BSNs enables remote wireless diagnosis of various health conditions. In this paper, we propose a novel layered architecture for smart healthcare system where health community service providers, patients, doctors and hospitals have access to real time data which has been gathered using various sensory mechanisms. An experimental case study has been implemented for evaluation. Early results show benefits of this system in improving the quality of health care.
如今,许多人,不仅仅是那些有健康问题的人,都越来越有健康意识。随着基于传感器技术的出现,创建可穿戴无线生物识别传感器网络成为可能,被称为身体传感器网络(BSNs),它允许人们收集他们的健康数据并将其远程发送以进行进一步分析和存储。研究表明,使用BSNs可以对各种健康状况进行远程无线诊断。在本文中,我们为智能医疗系统提出了一种新颖的分层架构,其中卫生社区服务提供者,患者,医生和医院可以访问使用各种感官机制收集的实时数据。为了进行评估,我们实施了一个实验案例研究。早期结果表明,该系统在提高医疗质量方面有好处。
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引用次数: 4
Model-based filtering and compression of oscillometric blood pressure pulses 基于模型的振荡血压脉冲滤波与压缩
Pub Date : 2016-05-15 DOI: 10.1109/MEMEA.2016.7533753
David Abolarin, M. Forouzanfar, V. Groza, S. Rajan, H. Dajani, E. Petriu
This paper presents a new approach toward outlier removal, filtering and compression of oscillometric blood pressure pulses by modeling the pulses as sum of harmonically related sinusoids. By curve fitting the proposed model to the measured oscillometric pulses using a nonlinear optimization technique, we demonstrate that an arbitrary oscillometric pulse can be modeled and consequently noise and artifacts can be reduced. As each sinusoid is precisely expressed by its amplitude, phase and frequency, the proposed method provides a compressed representation of the oscillometric pulses. We show that the proposed method achieves a compression ratio of 60 Fs/HR 2N+4, where HR is the heart rate in beats/min, Fs is the sampling frequency in Hz, and N is the number of harmonics considered in the model. New methods for detecting, replacing, and correcting the outliers based on the characteristics of the outlier neighboring pulses are also proposed in this paper.
本文提出了一种将血压振荡脉冲建模为谐波相关正弦波的和的方法来去除、滤波和压缩离群值。通过使用非线性优化技术将所提出的模型与测量的振荡脉冲进行曲线拟合,我们证明了任意振荡脉冲可以建模,从而可以减少噪声和伪影。由于每个正弦波都是由其幅度、相位和频率精确表示的,因此所提出的方法提供了振荡脉冲的压缩表示。我们表明,所提出的方法实现了60 Fs/HR 2N+4的压缩比,其中HR为心率,单位为beats/min, Fs为采样频率,单位为Hz, N为模型中考虑的谐波数。本文还提出了基于离群值相邻脉冲特性的离群值检测、替换和校正的新方法。
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引用次数: 1
Measurement of force and pressure distribution in walking for prosthesis design 假肢设计中行走力和压力分布的测量
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533797
Marianna Magni, B. Saggin, D. Scaccabarozzi, M. Tarabini
This work deals with measurement of the force and pressure distribution during walking of a patient with both feet not fully formed. Patient' legs are completely formed down to the heels and the beginning of one midfoot. Since the forefoot is missing, the subject has a difficult propulsion during the boost phase and an excessive rotation at the ankle due to an absent malleolar stability. Design of a customized prosthesis, conceived to ease the subject movement, required the measurement of the forces and pressure distributions during movement. In fact, existing trans-tibial and trans-femoral prostheses studies cannot be applied given that the patient has a limited ankle mobility that shall be preserved during the movement. The force and pressure distributions, measured by means of a commercial measurement system based on capacitive sensors, have been used as input for the finite elements based design. Models of the prostheses have been developed and the performed finite element analyses validated the preliminary design, allowing the manufacturing of prosthetic prototypes.
这项工作处理的力和压力分布的测量过程中,病人的双脚不完全形成。病人的腿完全成形,直到脚跟和一只中脚掌的开始。由于前脚缺失,受试者在推动阶段有困难推进,踝关节由于缺乏踝稳定性而过度旋转。定制假体的设计,旨在缓解受试者的运动,需要测量运动过程中的力和压力分布。事实上,现有的经胫骨和经股假体研究不能应用,因为患者的踝关节活动有限,在活动过程中需要保持踝关节活动。通过基于电容传感器的商业测量系统测量的力和压力分布已被用作基于有限元的设计的输入。假肢的模型已经开发出来,并进行了有限元分析,验证了初步设计,允许制造假肢原型。
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引用次数: 1
Optimization of flow setting during high-flow nasal cannula (HFNC) with a new spirometry system 基于新型肺量测量系统的高流量鼻插管血流设置优化
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533714
F. Montecchia, F. Midulla, C. Moretti, P. Papoff
High-flow nasal cannula (HFNC) is frequently used to treat respiratory distress in infants and children because of its beneficial effects on alveolar ventilation and respiratory mechanics. Setting an adequate flow rate that meets a patient's peak inspiratory flow (PIF) is thus crucially important to achieve such effects. HFNC flow rate is typically set at 1 L/min/kg +1 as suggested by the manufacturer and increased to 2 L/min/kg according to the degree of respiratory distress. However, whether this empirical flow setting actually meets a patient's PIF has not yet been investigated. In this study, we implemented our previously described respiratory mechanics monitoring system (MAES) with a new spirometry function (NSS) that allows for a simultaneous visualization of the flow tracings of HFNC and the patient's spontaneous breathing. We tested the ability of NSS-MAES to determine the adequacy of empirically set flow rates of 1 L/min/kg +1 or 2 L/min/kg on 9 infants with respiratory distress receiving HFNC. HFNC flow rate was considered adequate if its tracing was just above the patient's respiratory flow. In patients in whom 1 L/kg/min +1 was inadequate, we used NSS-MAES to identify the adequate flow by raising the HFNC flow until it reached the patient's PIF (HFNC_NSS-MAES). We also investigated which flow rate was associated with the maximal decrease of respiratory effort, namely, Pressure Time Product (PTP) and Work of Breathing (WOB). We found that 1 L/min/kg +1, but not 2 L/min/kg was often unable to meet the patient's PIF. In these cases HFNC_NSS-MAES values were around 1.6 L/min/kg. Conversely, HFNC at 2 L/min/kg always exceeded the patient's PIF. All breathing effort indexes tested improved after HFNC treatment with the maximal unloading seen at 2 L/min/kg for PTP and at HFNC_NSS-MAES.
高流量鼻插管(HFNC)因其对肺泡通气和呼吸力学的有益作用而被广泛用于婴幼儿呼吸窘迫的治疗。因此,设定一个足够的流量以满足患者的峰值吸气流量(PIF)对于达到这种效果至关重要。HFNC流量一般按厂家建议设置为1l /min/kg +1,根据呼吸窘迫程度增加到2l /min/kg。然而,这种经验流量设置是否真的符合患者的PIF还没有研究。在这项研究中,我们实现了我们之前描述的呼吸力学监测系统(MAES),该系统具有新的肺活量测定功能(NSS),可以同时可视化HFNC的血流追踪和患者的自发呼吸。我们测试了NSS-MAES对9名接受HFNC的呼吸窘迫婴儿确定经验设定的流量(1l /min/kg +1或2l /min/kg)的充分性的能力。如果追踪到的HFNC流量刚好高于患者的呼吸流量,则被认为是适当的。在1 L/kg/min +1不足的患者中,我们使用NSS-MAES通过提高HFNC流量直到达到患者PIF (HFNC_NSS-MAES)来识别足够的流量。我们还研究了哪种流速与呼吸功的最大减少有关,即压力时间积(PTP)和呼吸功(WOB)。我们发现1l /min/kg +1,而不是2l /min/kg往往不能满足患者的PIF。这些病例的HFNC_NSS-MAES值约为1.6 L/min/kg。相反,2 L/min/kg的HFNC总是超过患者的PIF。在HFNC治疗后,所有呼吸努力指标均有所改善,PTP和HFNC_NSS-MAES的最大卸载量为2 L/min/kg。
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引用次数: 2
Design of graphene-based MEMS intracranial pressure sensor 基于石墨烯的MEMS颅内压传感器设计
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533799
Siti Hajar Abd Rahman, N. Soin, F. Ibrahim
The present paper utilises COMSOL Multiphysics to model structural application of graphene as pressure sensor diaphragm. In this study, deflection and strain induced in a graphene diaphragm due to applied pressure were calculated. Pressure operation of the sensor is divided into two ranges, namely normal pressure and abnormal pressure to find the suitable design for these different pressure ranges. Changes in the band structure can be detected electrically, suggesting a potential application as the ultra-sensitive pressure sensor. This study has paved a new path to discover the feasibility of utilising the thinness of graphene membrane in MEMS piezoresistive pressure sensor specifically in intracranial pressure monitoring.
本文利用COMSOL Multiphysics模拟了石墨烯作为压力传感器膜片的结构应用。在这项研究中,计算了由于施加压力而引起的石墨烯薄膜的挠曲和应变。压力传感器的工作分为正常压力和异常压力两个量程,为这些不同的压力量程找到合适的设计。带结构的变化可以通过电来检测,这表明了超灵敏压力传感器的潜在应用。本研究为探索石墨烯薄膜厚度在MEMS压阻式压力传感器中应用于颅内压监测的可行性开辟了新的途径。
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引用次数: 6
Application of a new four-channel vibrometer for determination of atherosclerosis: Further advances towards a handheld device 一种新的四通道振动计在动脉粥样硬化测定中的应用:向手持设备的进一步发展
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533732
A. Campo, J. Dirckx, E. Widman, A. Waz, G. Dudzik, K. Abramski
Cardiovascular diseases (CD) are the leading cause of death worldwide and their prevalence is expected to rise. Important in the etiology of CD is the stiffening of the large arteries (arteriosclerosis) and plaque formation (atherosclerosis) in the common carotid artery (CCA). Increasing evidence shows that both arteriosclerosis and atherosclerosis can be detected by assessing pulse wave velocity (PWV) in the CCA, and several techniques focus on the detection of PWV in this structure. In previous studies, laser Doppler vibrometry (LDV) was proposed as an approach to detect arterial stiffness. In the present work, a compact four-channel LDV system is introduced for PWV detection. Four phantom arteries were assessed mimicking real life cardiovascular pathologies. Due to the high sensitivity and the increased spatial and temporal resolution of the LDV system, PWV could be assessed, and even local changes in phantom architecture could be detected. The system could potentially be used to detect arteriosclerosis and arterial plaque during cardiovascular screening.
心血管疾病(CD)是世界范围内导致死亡的主要原因,其患病率预计将上升。CD的重要病因是大动脉硬化(动脉硬化)和颈总动脉斑块形成(动脉粥样硬化)。越来越多的证据表明,动脉硬化和动脉粥样硬化都可以通过评估CCA中的脉搏波速度(PWV)来检测,并且有几种技术专注于检测该结构中的PWV。在以往的研究中,激光多普勒振动仪(LDV)被提出作为检测动脉僵硬度的方法。本文介绍了一种用于PWV检测的紧凑型四通道LDV系统。模拟现实生活中的心血管疾病,评估四条虚幻动脉。由于LDV系统的高灵敏度和增加的时空分辨率,可以评估PWV,甚至可以检测到幻体结构的局部变化。该系统有可能在心血管筛查过程中用于检测动脉硬化和动脉斑块。
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引用次数: 0
Investigation of ultrasonic fields produced by HIFU transducers used in cancer therapy 用于癌症治疗的HIFU换能器产生的超声场的研究
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533736
B. Karaboce, K. Kilic, Gizem Erdoğan
Ultrasonic fields induced by HIFU (High Intensity Focused Ultrasound) have been studied. Effect of input electrical power, harmonics and nonlinear propagation of the ultrasound fields has been quantized. Asymmetric waveforms with peak (+) pressures and peak (-) pressures were obtained both numerically and experimentally. Nonlinear propagation with harmonics output was dominant at higher intensities that leads to an increase of the compressional wave and a decrease of rarefactional wave. All measurements have been realized in the constructed system at National Metrology Institute of Turkey, TÜBİTAK UME. Set up includes a water reservoir, positioning system, HIFU transducers, needle hydrophone, power amplifier, signal generator, measurement and control devices which are all controlled by LabVIEW 8.1 software. P+, P- and P pressures have been determined theoretically for each waveform. Wave behaviors generated by the Khoklov-Zabolotskaya-Kuznetsov model (KZK model) and from experiments match in general. Decrease in size of focus point was shown in 3rd harmonic.
对高强度聚焦超声(HIFU)诱发的超声场进行了研究。对输入功率、谐波和超声场非线性传播的影响进行了量化。数值和实验均得到了峰值(+)压力和峰值(-)压力的不对称波形。在高强度下,以谐波输出为主的非线性传播导致纵波增大,反射波减小。所有测量都是在土耳其国家计量研究所(TÜBİTAK UME)构建的系统中实现的。设置包括水库、定位系统、HIFU换能器、针式水听器、功率放大器、信号发生器、测量和控制装置,全部由LabVIEW 8.1软件控制。每个波形的P+、P-和P压力都已从理论上确定。由Khoklov-Zabolotskaya-Kuznetsov模型(KZK模型)产生的波动行为与实验结果基本吻合。在三次谐波中,焦点的大小减小。
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引用次数: 0
Spitz nevus versus atypical Spitz tumor: Objective morphological differentiation by digital dermoscopy analysis 斯皮兹痣与非典型斯皮兹瘤:数字皮肤镜分析的客观形态学区分
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533792
P. Rubegni, L. Tognetti, M. Pellegrino, M. Burroni, M. Fimiani, C. Miracco, E. Cinotti, F. Cambazard, R. Bono, G. Cevenini
Spitzoid melanocytic skin lesions (MSL) include Spitz nevi (SN) and spitzoid melanomas (SM). A third rare subset was described, atypical spitz tumors (AST), that share overlapping histologic features of SN and SM. Being difficult to diagnose lesions, both with dermoscopy and histology, there is considerable uncertainty regarding their biological potential. We aimed to investigate if digital dermoscopy analysis (DDA) could select some significantly different features in 41 dermoscopic images including 19 SN and 21 AST. Stepwise logistic regression analysis was performed in order to verify if there were dermoscopic features able to discriminate between SN and AST. No significant dermoscopic criteria were found to distinguish AST from SN. This support the hypothesis that AST was should be considered not as a different entity but within the spectrum of AN lesions.
Spitzoid melanocytic skin lesion (MSL)包括Spitz nevi (SN)和Spitzoid melanomas (SM)。第三个罕见的亚群被描述为非典型spitz肿瘤(AST),具有SN和SM重叠的组织学特征。很难诊断病变,无论是皮肤镜检查和组织学,有相当大的不确定性,其生物学潜力。我们的目的是研究数字皮肤镜分析(DDA)是否可以从41张皮肤镜图像中选择一些显著不同的特征,包括19张SN和21张AST。为了验证是否存在能够区分SN和AST的皮肤镜特征,我们进行了逐步逻辑回归分析。这支持了AST不应被视为一个不同的实体,而应被视为AN病变范围内的假设。
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引用次数: 5
期刊
2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
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