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2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)最新文献

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On the positive and negative syndrome scale and remission in schizophrenia 精神分裂症阳性、阴性综合征量表与缓解
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533774
E. Nicotra, G. Casu, S. Piras, Mario Palomba, G. Marchese
The positive and negative syndrome scale (PANSS) and Andreasen remission criteria have contextually been used to characterize schizophrenia symptoms in clinical trials. However, few studies have investigated the relationships among the possible scores of these two psychometric tools. The present study intends to address this topic starting from a theoretical combinatorial analysis of the possible dispositions with replacement that could be generated by the two scales. The results indicated that the probability to fully accomplish Andreasen remission criteria is enclosed in a very narrow window, because of the huge amount of possible dispositions with replacement of PANSS. Conversely, the probability to accomplish the remission criteria only for the general psychopathology PANSS subscale was unexpectedly elevate. The observed differences among the probabilities to attain remission within PANSS scale are possibly related to the approach in modeling schizophrenia syndrome. The symptomatic features of individuals enrolled in clinical trials should be carefully analyzed when both PANSS and Andreasen remission criteria are used to assess schizophrenia symptoms.
阳性和阴性症状量表(PANSS)和Andreasen缓解标准已在临床试验中用于表征精神分裂症症状。然而,很少有研究调查了这两种心理测量工具的可能得分之间的关系。本研究拟从理论组合分析两个量表可能产生的具有替代的可能倾向开始解决这一问题。结果表明,完全达到安瑞森缓解标准的概率被封闭在一个非常窄的窗口内,因为有大量可能的处置与更换PANSS。相反,仅在一般精神病理PANSS量表中达到缓解标准的概率出乎意料地提高。在PANSS量表中观察到的缓解概率的差异可能与精神分裂症综合征建模的方法有关。当使用PANSS和Andreasen缓解标准来评估精神分裂症症状时,应仔细分析参加临床试验的个体的症状特征。
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引用次数: 1
Evaluation of a Stretch Sensor for its inedited application in tracking hand finger movements 一种伸缩传感器在手部手指运动跟踪中的应用评价
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533809
Laura Sbernini, A. Pallotti, G. Saggio
Flex sensors are frequently used as wearable tools for unobtrusively tracking human joint movements. Among all the flex sensor types, the resistive ones are the mostly adopted thanks to their electrical and mechanical properties capable to furnish electrical resistance values related to the amount of mechanical flexion. In particular, resistive flex sensors have been finding many applications when embedded into gloves, in order to evaluate fine flexion/extension movements of the finger joints. Within this frame, here we investigate the possible utilization of a different type of flex sensors embedded into gloves, i.e., the stretch ones, since the stretch sensors change in resistance proportionally to their stretch that can be just obtained when laid on-top of a finger joint. In such a view, here we compare the characteristics of commercial flex and stretch sensors obtained by means of an ad-hoc setup and protocol. Results demonstrate the different peculiarities of the two different types of sensors, so to determine when it is convenient to adopt one type instead of the other.
柔性传感器经常被用作可穿戴工具,用于不显眼地跟踪人体关节运动。在所有类型的挠曲传感器中,电阻型是采用最多的,因为它们的电气和机械性能能够提供与机械挠曲量相关的电阻值。特别是,电阻式弯曲传感器在嵌入手套时已经发现了许多应用,以评估手指关节的精细弯曲/伸展运动。在这个框架内,这里我们研究了嵌入手套的不同类型的弯曲传感器的可能利用,即拉伸传感器,因为拉伸传感器的电阻变化与它们的拉伸成比例,当放置在手指关节的顶部时可以获得。在这种观点下,我们在这里比较了商业弯曲和拉伸传感器的特性,这些传感器是通过一种特别的设置和协议获得的。结果显示了两种不同类型传感器的不同特性,从而确定何时采用一种而不是另一种更方便。
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引用次数: 9
Development of an automatic sleep-wake staging method for rats 大鼠睡眠-觉醒自动分期方法的建立
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533742
Ting-Ying Wei, C. Young
The study proposed an automated sleep-wake scoring system by using the features of electroencephalogram (EEG) and electromyogram (EMG). The method of normalization has been used to reduce the difference of features between the subjects. The proposed system would automatically discriminate the sleep-wake states into both three-state (waking, NREM and REM) and five-state (waking, NREM stage 1, NREM stage 2, transition sleep, and REM). The automated scoring results were compared with the manual scoring results that scored by the experts. The results of global agreement between the automated scoring and experts consensus in three-state scoring are 92.5% (κ=0.88) and 95.3% (κ=0.91) in five-state scoring. The results indicated that the performance of the automated sleep-wake staging system has highly reliability and accuracy.
本研究提出了一种利用脑电图(EEG)和肌电图(EMG)特征的自动睡眠-觉醒评分系统。采用归一化的方法来减少受试者之间的特征差异。该系统将自动将睡眠-觉醒状态分为三状态(清醒、非快速眼动和快速眼动)和五状态(清醒、非快速眼动阶段1、非快速眼动阶段2、过渡睡眠和快速眼动)。将自动评分结果与专家打分的人工评分结果进行比较。自动评分与专家共识在三状态评分中的全局一致性为92.5% (κ=0.88),在五状态评分中的全局一致性为95.3% (κ=0.91)。结果表明,该自动睡眠-觉醒分期系统具有较高的可靠性和准确性。
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引用次数: 0
Improvements in haematology for home health assistance and monitoring by a web based communication system 通过基于网络的通信系统改善家庭健康援助和监测血液学
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533762
A. Galiano, A. Massaro, Bachir Boussahel, D. Barbuzzi, Francesco Tarulli, L. Pellicani, Lino Renna, A. Guarini, G. Tullio, Giovanni Nardelli, Roberto Bonaduce, C. Minoia, S. Ciavarella, V. Fazio, A. Negri, Caterina Marchionna
The authors have developed, in the field of a national project, an innovative communication system based on a web cloud platform oriented on the home-monitoring and home-assistance useful for de-hospitalization process. The goal of the work is to provide a tool for the hospital, able to manage different certified medical devices measuring data from patients at home. This management is provided by a web server system compatible with different devices and by a front-end panel able to register and to store data coming from these devices. The innovation is manly in the possibility to transfer the analyses from home to hospital thus reducing costs and providing more assistance and support to patients. The implemented database system represents a first step for future scientific studies and predictions requiring BigData storage.
在一个国家项目中,作者开发了一个基于面向家庭监控和家庭援助的网络云平台的创新通信系统,该系统对去住院过程有用。这项工作的目标是为医院提供一种工具,能够管理来自家中患者的不同认证医疗设备的测量数据。这种管理是由与不同设备兼容的web服务器系统和能够注册和存储来自这些设备的数据的前端面板提供的。创新之处在于可以将分析从家庭转移到医院,从而降低成本,并为患者提供更多的帮助和支持。实现的数据库系统代表了未来需要大数据存储的科学研究和预测的第一步。
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引用次数: 7
Wearable instrument to measure simultaneously cardiac and electrodermal activities 同时测量心脏和皮肤电活动的穿戴式仪器
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533749
A. Affanni
The paper presents the design and characterization of a wearable instrument which measures simultaneously the electrodermal activity and the heart rate variability. The device measures the electrocardiogram on three channels and the skin potential response (endosomatic electrodermal activity) with a sample rate 1 kSa/s, 12 bits resolution. The bandwidth of ECG channels is [0.025, 160] Hz and the bandwidth of electrodermal channel is [0.08, 40] Hz. Data are transmitted via Bluetooth to a developed graphical user interface, which can run on a laptop or smartphone/tablet. The system is a useful tool to assess the sympathetic activity on heart rate variability.
本文介绍了一种可同时测量皮肤电活动和心率变异性的可穿戴仪器的设计和特性。该装置以1 kSa/s的采样率,12位分辨率测量三个通道上的心电图和皮肤电位反应(内体皮电活动)。心电通道带宽为[0.025,160]Hz,皮肤电通道带宽为[0.08,40]Hz。数据通过蓝牙传输到一个开发的图形用户界面,可以在笔记本电脑或智能手机/平板电脑上运行。该系统是评估交感神经活动对心率变异性的有用工具。
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引用次数: 12
Impact of motion artifacts on video-based non-intrusive heart rate measurement 运动伪影对视频非侵入式心率测量的影响
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533740
Jelena Nikolic-Popovic, R. Goubran
Measuring vital signs such as heart rate using a camera has the potential to enable better health monitoring for subjects at risk and as such enhance their quality of life. Applications could include driver monitoring via in-dash camera, critical function operator monitoring at work, or remote health monitoring via a webcam. For such a system to be feasible however, it needs to be work well in realistic scenarios where the subject does not sit completely still in front of a camera. Motion artifacts, if not taken into account when designing the system, yield inaccurate results and potentially create false alarms. In this paper, we start with a popular algorithm for extracting heart rate from video based on spatial and temporal filtering, quantify how key parameters used in the algorithm affect its performance in situations when the subject is not sitting still, analyze in detail the performance of the filtering approach in videos with motion, identify issues, and propose approaches to overcome those limitations. The paper shows that the use of wider filters and more levels in the Gaussian pyramid lead to a better performance when the subject is moving, but that the motion artifacts dominate the extracted signal.
使用摄像机测量心率等生命体征有可能为处于危险中的受试者提供更好的健康监测,从而提高他们的生活质量。应用可能包括通过车内摄像头监控驾驶员,关键功能操作员在工作中监控,或通过网络摄像头远程健康监控。然而,对于这样一个系统是可行的,它需要在现实的场景中工作得很好,在这个场景中,拍摄对象并不是完全静止地坐在相机前。如果在设计系统时不考虑运动伪影,则会产生不准确的结果并可能产生假警报。在本文中,我们从一种基于时空滤波的从视频中提取心率的流行算法开始,量化算法中使用的关键参数在受试者不静止的情况下如何影响其性能,详细分析滤波方法在运动视频中的性能,识别问题,并提出克服这些限制的方法。本文表明,在高斯金字塔中使用更宽的滤波器和更多的电平可以在对象运动时获得更好的性能,但运动伪影支配了提取的信号。
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引用次数: 10
VoxTester, software for digital evaluation of speech changes in Parkinson disease VoxTester,用于帕金森病患者言语变化数字评估的软件
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533761
G. Dimauro, D. Caivano, Vitoantonio Bevilacqua, Francesco Girardi, V. Napoletano
Patients with Parkinson's disease may have difficulties in speaking because of the reduced coordination of the muscles that control breathing, phonation, articulation and prosody. Symptoms that may occur because of changes are weakening of the volume of the voice, voice monotony, changes in the quality of the voice, speed of speech, uncontrolled repetition of words. The evaluation of some of the disorders mentioned can be achieved through measuring the variation of parameters in an objective manner. It may be done to evaluate the response to the treatments with intra-daily frequency pre / post-treatment, as well as in the long term. Software systems allow these measurements also by recording the patient's voice. This allows to carry out a large number of tests by means of a larger number of patients and a higher frequency of the measurements. The main goal of our work was to design and realize Voxtester, an effective and simple to use software system useful to measure whether changes in voice emission are sensitive to pharmacologic treatments. Doctors and speech therapists can easily use it without going into the technical details, and we think that this goal is reached only by Voxtester, up to date.
帕金森氏症患者可能有说话困难,因为控制呼吸、发音、发音和韵律的肌肉协调性降低。这些变化可能导致的症状有:声音的音量变弱、声音单调、声音的质量、说话速度、不受控制地重复单词。对上述某些疾病的评价可以通过客观地测量参数变化来实现。可以用每日频率来评估治疗前/治疗后的反应,也可以长期评估。软件系统也可以通过记录病人的声音来进行这些测量。这样就可以通过更多的病人和更高的测量频率来进行大量的测试。我们的工作的主要目标是设计和实现Voxtester,一个有效的和简单易用的软件系统,用于测量声音发射的变化是否对药物治疗敏感。医生和语言治疗师可以很容易地使用它,而不需要了解技术细节,我们认为只有Voxtester才能达到这个目标。
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引用次数: 22
Effect of limbs' motion on pulse oximetry in preterm infants 早产儿肢体运动对脉搏血氧测定的影响
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533788
P. Marchionni, L. Scalise, I. Ercoli, M. Palazzi, V. Carnielli
Pulse oximetry (PO) is a measurement method used to determine the percentage of blood that is loaded with oxygen (oxygen saturation). It is an easy-to-sue, safe, convenient, inexpensive, painless and noninvasive measurement method for the assessment of oxygen content in the circulatory system and it also allows to measure the pulse frequency (coincident to the heart rate). It is frequently asses in intensive care, in particular in neonatal one and it provides information on the adequacy of cardio/respiratory function. Motion artifacts can largely influence PO measurement performances. The aim of this paper is to compare the PO measurement data obtained (test population: 5 subjects; test duration 2 hours) on fixed limb to the ones obtained in a free-to-move limb conditions, using 2 PO systems applied on the patient limbs. Despite to the manufacturers claimed accuracy data (>2%), we report differences >3.4% on the saturation data between free and fixed limb.
脉搏血氧仪(PO)是一种测量方法,用于确定血氧负荷百分比(血氧饱和度)。它是一种简单、安全、方便、廉价、无痛和无创的测量方法,用于评估循环系统中的氧含量,它还可以测量脉搏频率(与心率一致)。它经常在重症监护中进行评估,特别是在新生儿中,它提供了关于心肺功能是否充足的信息。运动伪影在很大程度上影响PO测量性能。本文的目的是比较所获得的PO测量数据(测试人群:5名受试者;测试持续时间2小时),在固定肢体条件下获得的,在自由移动的肢体条件下,使用2个PO系统应用于患者肢体。尽管制造商声称精度数据(>2%),但我们报告了自由肢和固定肢之间饱和度数据的差异>3.4%。
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引用次数: 4
Model simulations and comparative evaluations of susceptibility-based and gadolinium contrast enhancement for high-resolution brain venography 高分辨率脑静脉造影中基于敏感性和钆造影剂增强的模型模拟和比较评估
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533729
E. Casciaro, R. Franchini, F. Conversano, P. Pisani, S. Casciaro, A. Lay-Ekuakille
The MRI signal, in terms of amplitude and phase, was simulated for susceptibility-based brain venography (BV) without and with administration of contrast agent (CA) under standard clinical parameters and field magnitude of 1.5 T (Tesla). Then, in order to compare the enhancement due to CA and that one obtained through susceptibility weighted magnitude image (SWI) processing, exploiting only the intrinsic magnetic susceptibility differences between blood and surrounding tissue, the simulated signal was processed with a well-known phase masking technique to increase signal differences as a function of tissue type, thus generating better image contrast. The simulation was carried out adopting a well-established bi-compartmental model, described by a set of analytical formulas. The based simulated signal was processed with the SWI technique considering a conventional masking procedure available in literature and a different masking method designed and described in our previous work. The resulting enhanced signals in terms of image contrast obtained with these two different phase masking procedures and with the administration of conventional CA were compared. The new designed mask (DM), compared with the conventional one, allows to get better results in terms of image contrast for all blood volume fractions considered in the simulation. Additionally, better results can be obtained also with respect to the case of CA administration only. Results from model simulations demonstrate the effectiveness of masking techniques to improve image contrast regarding all vessel sizes of clinical interest in the high resolution susceptibility-based brain venography possibly avoiding, in some cases, the need for CA administration.
在标准临床参数和1.5 T(特斯拉)场强下,模拟无对比剂(CA)和有对比剂(CA)的基于敏感性的脑静脉造影(BV)的MRI信号的振幅和相位。然后,为了比较CA和敏感性加权幅度图像(SWI)处理得到的增强,只利用血液和周围组织之间的固有磁化率差异,用众所周知的相位掩蔽技术对模拟信号进行处理,增加信号差异作为组织类型的函数,从而产生更好的图像对比度。模拟采用了一个完善的双区室模型,由一组解析公式描述。基于模拟信号的SWI技术考虑了文献中可用的传统掩蔽程序和我们之前工作中设计和描述的不同掩蔽方法。通过比较这两种不同的相位掩蔽程序和常规CA管理获得的图像对比度方面的增强信号。与传统掩膜相比,新设计的掩膜(DM)可以在模拟中考虑的所有血容量分数的图像对比度方面获得更好的结果。此外,仅在CA管理的情况下也可以获得更好的结果。模型模拟的结果表明,在高分辨率基于敏感性的脑静脉造影中,掩蔽技术可以有效地提高临床感兴趣的所有血管大小的图像对比度,在某些情况下可能避免需要CA。
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引用次数: 0
A preliminary uncertainty analysis of acceleration and displacement measurements on a novel WBV platform for biologic response studies 一种用于生物反应研究的新型WBV平台上加速度和位移测量的初步不确定性分析
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533722
F. Orsini, A. Scorza, A. Rossi, F. Botta, S. Sciuto, R. D. Giminiani
Over the last decade, many studies have been conducted on the effects of mechanical vibration on the physical hormonal and neuromuscular responses of muscles: in some works the growth hormone response showed a dependence on the acceleration provided by Whole Body Vibration (WBV) platforms with respect to subjects responsiveness. Therefore the accuracy of acceleration measurements related to the excitation system is important and should be assessed. To this aim a preliminary study on the identification and evaluation of the measurement uncertainty sources in the measurement chain of a novel WBV platform developed by the Authors is here proposed. After the main measurement error sources have been identified, a Monte Carlo simulation Method has been implemented to obtain the uncertainty in accelerations and displacements provided by the WBV platform. Since main causes of uncertainty has been identified in the accelerometer sensitivity, its mounting and the data acquisition processing, Results of the test showed a relative uncertainty of about ±4% for acceleration and displacement measurements for frequencies between 20Hz and 60Hz.
在过去的十年中,许多关于机械振动对肌肉的生理激素和神经肌肉反应的影响的研究已经进行了:在一些工作中,生长激素的反应显示出对全身振动(WBV)平台提供的加速度的依赖。因此,与励磁系统有关的加速度测量的准确性是重要的,应该进行评估。为此,本文提出了一种新型WBV平台测量链中测量不确定度源识别与评估的初步研究。在确定了主要测量误差源后,采用蒙特卡罗仿真方法获得了WBV平台提供的加速度和位移的不确定度。由于在加速度计的灵敏度、安装和数据采集处理中确定了不确定度的主要原因,测试结果表明,频率在20Hz和60Hz之间的加速度和位移测量的相对不确定度约为±4%。
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引用次数: 10
期刊
2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
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