Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533774
E. Nicotra, G. Casu, S. Piras, Mario Palomba, G. Marchese
The positive and negative syndrome scale (PANSS) and Andreasen remission criteria have contextually been used to characterize schizophrenia symptoms in clinical trials. However, few studies have investigated the relationships among the possible scores of these two psychometric tools. The present study intends to address this topic starting from a theoretical combinatorial analysis of the possible dispositions with replacement that could be generated by the two scales. The results indicated that the probability to fully accomplish Andreasen remission criteria is enclosed in a very narrow window, because of the huge amount of possible dispositions with replacement of PANSS. Conversely, the probability to accomplish the remission criteria only for the general psychopathology PANSS subscale was unexpectedly elevate. The observed differences among the probabilities to attain remission within PANSS scale are possibly related to the approach in modeling schizophrenia syndrome. The symptomatic features of individuals enrolled in clinical trials should be carefully analyzed when both PANSS and Andreasen remission criteria are used to assess schizophrenia symptoms.
{"title":"On the positive and negative syndrome scale and remission in schizophrenia","authors":"E. Nicotra, G. Casu, S. Piras, Mario Palomba, G. Marchese","doi":"10.1109/MeMeA.2016.7533774","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533774","url":null,"abstract":"The positive and negative syndrome scale (PANSS) and Andreasen remission criteria have contextually been used to characterize schizophrenia symptoms in clinical trials. However, few studies have investigated the relationships among the possible scores of these two psychometric tools. The present study intends to address this topic starting from a theoretical combinatorial analysis of the possible dispositions with replacement that could be generated by the two scales. The results indicated that the probability to fully accomplish Andreasen remission criteria is enclosed in a very narrow window, because of the huge amount of possible dispositions with replacement of PANSS. Conversely, the probability to accomplish the remission criteria only for the general psychopathology PANSS subscale was unexpectedly elevate. The observed differences among the probabilities to attain remission within PANSS scale are possibly related to the approach in modeling schizophrenia syndrome. The symptomatic features of individuals enrolled in clinical trials should be carefully analyzed when both PANSS and Andreasen remission criteria are used to assess schizophrenia symptoms.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114597115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533809
Laura Sbernini, A. Pallotti, G. Saggio
Flex sensors are frequently used as wearable tools for unobtrusively tracking human joint movements. Among all the flex sensor types, the resistive ones are the mostly adopted thanks to their electrical and mechanical properties capable to furnish electrical resistance values related to the amount of mechanical flexion. In particular, resistive flex sensors have been finding many applications when embedded into gloves, in order to evaluate fine flexion/extension movements of the finger joints. Within this frame, here we investigate the possible utilization of a different type of flex sensors embedded into gloves, i.e., the stretch ones, since the stretch sensors change in resistance proportionally to their stretch that can be just obtained when laid on-top of a finger joint. In such a view, here we compare the characteristics of commercial flex and stretch sensors obtained by means of an ad-hoc setup and protocol. Results demonstrate the different peculiarities of the two different types of sensors, so to determine when it is convenient to adopt one type instead of the other.
{"title":"Evaluation of a Stretch Sensor for its inedited application in tracking hand finger movements","authors":"Laura Sbernini, A. Pallotti, G. Saggio","doi":"10.1109/MeMeA.2016.7533809","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533809","url":null,"abstract":"Flex sensors are frequently used as wearable tools for unobtrusively tracking human joint movements. Among all the flex sensor types, the resistive ones are the mostly adopted thanks to their electrical and mechanical properties capable to furnish electrical resistance values related to the amount of mechanical flexion. In particular, resistive flex sensors have been finding many applications when embedded into gloves, in order to evaluate fine flexion/extension movements of the finger joints. Within this frame, here we investigate the possible utilization of a different type of flex sensors embedded into gloves, i.e., the stretch ones, since the stretch sensors change in resistance proportionally to their stretch that can be just obtained when laid on-top of a finger joint. In such a view, here we compare the characteristics of commercial flex and stretch sensors obtained by means of an ad-hoc setup and protocol. Results demonstrate the different peculiarities of the two different types of sensors, so to determine when it is convenient to adopt one type instead of the other.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122164056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533742
Ting-Ying Wei, C. Young
The study proposed an automated sleep-wake scoring system by using the features of electroencephalogram (EEG) and electromyogram (EMG). The method of normalization has been used to reduce the difference of features between the subjects. The proposed system would automatically discriminate the sleep-wake states into both three-state (waking, NREM and REM) and five-state (waking, NREM stage 1, NREM stage 2, transition sleep, and REM). The automated scoring results were compared with the manual scoring results that scored by the experts. The results of global agreement between the automated scoring and experts consensus in three-state scoring are 92.5% (κ=0.88) and 95.3% (κ=0.91) in five-state scoring. The results indicated that the performance of the automated sleep-wake staging system has highly reliability and accuracy.
{"title":"Development of an automatic sleep-wake staging method for rats","authors":"Ting-Ying Wei, C. Young","doi":"10.1109/MeMeA.2016.7533742","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533742","url":null,"abstract":"The study proposed an automated sleep-wake scoring system by using the features of electroencephalogram (EEG) and electromyogram (EMG). The method of normalization has been used to reduce the difference of features between the subjects. The proposed system would automatically discriminate the sleep-wake states into both three-state (waking, NREM and REM) and five-state (waking, NREM stage 1, NREM stage 2, transition sleep, and REM). The automated scoring results were compared with the manual scoring results that scored by the experts. The results of global agreement between the automated scoring and experts consensus in three-state scoring are 92.5% (κ=0.88) and 95.3% (κ=0.91) in five-state scoring. The results indicated that the performance of the automated sleep-wake staging system has highly reliability and accuracy.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129426733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533762
A. Galiano, A. Massaro, Bachir Boussahel, D. Barbuzzi, Francesco Tarulli, L. Pellicani, Lino Renna, A. Guarini, G. Tullio, Giovanni Nardelli, Roberto Bonaduce, C. Minoia, S. Ciavarella, V. Fazio, A. Negri, Caterina Marchionna
The authors have developed, in the field of a national project, an innovative communication system based on a web cloud platform oriented on the home-monitoring and home-assistance useful for de-hospitalization process. The goal of the work is to provide a tool for the hospital, able to manage different certified medical devices measuring data from patients at home. This management is provided by a web server system compatible with different devices and by a front-end panel able to register and to store data coming from these devices. The innovation is manly in the possibility to transfer the analyses from home to hospital thus reducing costs and providing more assistance and support to patients. The implemented database system represents a first step for future scientific studies and predictions requiring BigData storage.
{"title":"Improvements in haematology for home health assistance and monitoring by a web based communication system","authors":"A. Galiano, A. Massaro, Bachir Boussahel, D. Barbuzzi, Francesco Tarulli, L. Pellicani, Lino Renna, A. Guarini, G. Tullio, Giovanni Nardelli, Roberto Bonaduce, C. Minoia, S. Ciavarella, V. Fazio, A. Negri, Caterina Marchionna","doi":"10.1109/MeMeA.2016.7533762","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533762","url":null,"abstract":"The authors have developed, in the field of a national project, an innovative communication system based on a web cloud platform oriented on the home-monitoring and home-assistance useful for de-hospitalization process. The goal of the work is to provide a tool for the hospital, able to manage different certified medical devices measuring data from patients at home. This management is provided by a web server system compatible with different devices and by a front-end panel able to register and to store data coming from these devices. The innovation is manly in the possibility to transfer the analyses from home to hospital thus reducing costs and providing more assistance and support to patients. The implemented database system represents a first step for future scientific studies and predictions requiring BigData storage.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123746579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533749
A. Affanni
The paper presents the design and characterization of a wearable instrument which measures simultaneously the electrodermal activity and the heart rate variability. The device measures the electrocardiogram on three channels and the skin potential response (endosomatic electrodermal activity) with a sample rate 1 kSa/s, 12 bits resolution. The bandwidth of ECG channels is [0.025, 160] Hz and the bandwidth of electrodermal channel is [0.08, 40] Hz. Data are transmitted via Bluetooth to a developed graphical user interface, which can run on a laptop or smartphone/tablet. The system is a useful tool to assess the sympathetic activity on heart rate variability.
{"title":"Wearable instrument to measure simultaneously cardiac and electrodermal activities","authors":"A. Affanni","doi":"10.1109/MeMeA.2016.7533749","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533749","url":null,"abstract":"The paper presents the design and characterization of a wearable instrument which measures simultaneously the electrodermal activity and the heart rate variability. The device measures the electrocardiogram on three channels and the skin potential response (endosomatic electrodermal activity) with a sample rate 1 kSa/s, 12 bits resolution. The bandwidth of ECG channels is [0.025, 160] Hz and the bandwidth of electrodermal channel is [0.08, 40] Hz. Data are transmitted via Bluetooth to a developed graphical user interface, which can run on a laptop or smartphone/tablet. The system is a useful tool to assess the sympathetic activity on heart rate variability.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126414511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533740
Jelena Nikolic-Popovic, R. Goubran
Measuring vital signs such as heart rate using a camera has the potential to enable better health monitoring for subjects at risk and as such enhance their quality of life. Applications could include driver monitoring via in-dash camera, critical function operator monitoring at work, or remote health monitoring via a webcam. For such a system to be feasible however, it needs to be work well in realistic scenarios where the subject does not sit completely still in front of a camera. Motion artifacts, if not taken into account when designing the system, yield inaccurate results and potentially create false alarms. In this paper, we start with a popular algorithm for extracting heart rate from video based on spatial and temporal filtering, quantify how key parameters used in the algorithm affect its performance in situations when the subject is not sitting still, analyze in detail the performance of the filtering approach in videos with motion, identify issues, and propose approaches to overcome those limitations. The paper shows that the use of wider filters and more levels in the Gaussian pyramid lead to a better performance when the subject is moving, but that the motion artifacts dominate the extracted signal.
{"title":"Impact of motion artifacts on video-based non-intrusive heart rate measurement","authors":"Jelena Nikolic-Popovic, R. Goubran","doi":"10.1109/MeMeA.2016.7533740","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533740","url":null,"abstract":"Measuring vital signs such as heart rate using a camera has the potential to enable better health monitoring for subjects at risk and as such enhance their quality of life. Applications could include driver monitoring via in-dash camera, critical function operator monitoring at work, or remote health monitoring via a webcam. For such a system to be feasible however, it needs to be work well in realistic scenarios where the subject does not sit completely still in front of a camera. Motion artifacts, if not taken into account when designing the system, yield inaccurate results and potentially create false alarms. In this paper, we start with a popular algorithm for extracting heart rate from video based on spatial and temporal filtering, quantify how key parameters used in the algorithm affect its performance in situations when the subject is not sitting still, analyze in detail the performance of the filtering approach in videos with motion, identify issues, and propose approaches to overcome those limitations. The paper shows that the use of wider filters and more levels in the Gaussian pyramid lead to a better performance when the subject is moving, but that the motion artifacts dominate the extracted signal.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127374757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533761
G. Dimauro, D. Caivano, Vitoantonio Bevilacqua, Francesco Girardi, V. Napoletano
Patients with Parkinson's disease may have difficulties in speaking because of the reduced coordination of the muscles that control breathing, phonation, articulation and prosody. Symptoms that may occur because of changes are weakening of the volume of the voice, voice monotony, changes in the quality of the voice, speed of speech, uncontrolled repetition of words. The evaluation of some of the disorders mentioned can be achieved through measuring the variation of parameters in an objective manner. It may be done to evaluate the response to the treatments with intra-daily frequency pre / post-treatment, as well as in the long term. Software systems allow these measurements also by recording the patient's voice. This allows to carry out a large number of tests by means of a larger number of patients and a higher frequency of the measurements. The main goal of our work was to design and realize Voxtester, an effective and simple to use software system useful to measure whether changes in voice emission are sensitive to pharmacologic treatments. Doctors and speech therapists can easily use it without going into the technical details, and we think that this goal is reached only by Voxtester, up to date.
{"title":"VoxTester, software for digital evaluation of speech changes in Parkinson disease","authors":"G. Dimauro, D. Caivano, Vitoantonio Bevilacqua, Francesco Girardi, V. Napoletano","doi":"10.1109/MeMeA.2016.7533761","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533761","url":null,"abstract":"Patients with Parkinson's disease may have difficulties in speaking because of the reduced coordination of the muscles that control breathing, phonation, articulation and prosody. Symptoms that may occur because of changes are weakening of the volume of the voice, voice monotony, changes in the quality of the voice, speed of speech, uncontrolled repetition of words. The evaluation of some of the disorders mentioned can be achieved through measuring the variation of parameters in an objective manner. It may be done to evaluate the response to the treatments with intra-daily frequency pre / post-treatment, as well as in the long term. Software systems allow these measurements also by recording the patient's voice. This allows to carry out a large number of tests by means of a larger number of patients and a higher frequency of the measurements. The main goal of our work was to design and realize Voxtester, an effective and simple to use software system useful to measure whether changes in voice emission are sensitive to pharmacologic treatments. Doctors and speech therapists can easily use it without going into the technical details, and we think that this goal is reached only by Voxtester, up to date.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130327171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533788
P. Marchionni, L. Scalise, I. Ercoli, M. Palazzi, V. Carnielli
Pulse oximetry (PO) is a measurement method used to determine the percentage of blood that is loaded with oxygen (oxygen saturation). It is an easy-to-sue, safe, convenient, inexpensive, painless and noninvasive measurement method for the assessment of oxygen content in the circulatory system and it also allows to measure the pulse frequency (coincident to the heart rate). It is frequently asses in intensive care, in particular in neonatal one and it provides information on the adequacy of cardio/respiratory function. Motion artifacts can largely influence PO measurement performances. The aim of this paper is to compare the PO measurement data obtained (test population: 5 subjects; test duration 2 hours) on fixed limb to the ones obtained in a free-to-move limb conditions, using 2 PO systems applied on the patient limbs. Despite to the manufacturers claimed accuracy data (>2%), we report differences >3.4% on the saturation data between free and fixed limb.
{"title":"Effect of limbs' motion on pulse oximetry in preterm infants","authors":"P. Marchionni, L. Scalise, I. Ercoli, M. Palazzi, V. Carnielli","doi":"10.1109/MeMeA.2016.7533788","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533788","url":null,"abstract":"Pulse oximetry (PO) is a measurement method used to determine the percentage of blood that is loaded with oxygen (oxygen saturation). It is an easy-to-sue, safe, convenient, inexpensive, painless and noninvasive measurement method for the assessment of oxygen content in the circulatory system and it also allows to measure the pulse frequency (coincident to the heart rate). It is frequently asses in intensive care, in particular in neonatal one and it provides information on the adequacy of cardio/respiratory function. Motion artifacts can largely influence PO measurement performances. The aim of this paper is to compare the PO measurement data obtained (test population: 5 subjects; test duration 2 hours) on fixed limb to the ones obtained in a free-to-move limb conditions, using 2 PO systems applied on the patient limbs. Despite to the manufacturers claimed accuracy data (>2%), we report differences >3.4% on the saturation data between free and fixed limb.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"58 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131521700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533729
E. Casciaro, R. Franchini, F. Conversano, P. Pisani, S. Casciaro, A. Lay-Ekuakille
The MRI signal, in terms of amplitude and phase, was simulated for susceptibility-based brain venography (BV) without and with administration of contrast agent (CA) under standard clinical parameters and field magnitude of 1.5 T (Tesla). Then, in order to compare the enhancement due to CA and that one obtained through susceptibility weighted magnitude image (SWI) processing, exploiting only the intrinsic magnetic susceptibility differences between blood and surrounding tissue, the simulated signal was processed with a well-known phase masking technique to increase signal differences as a function of tissue type, thus generating better image contrast. The simulation was carried out adopting a well-established bi-compartmental model, described by a set of analytical formulas. The based simulated signal was processed with the SWI technique considering a conventional masking procedure available in literature and a different masking method designed and described in our previous work. The resulting enhanced signals in terms of image contrast obtained with these two different phase masking procedures and with the administration of conventional CA were compared. The new designed mask (DM), compared with the conventional one, allows to get better results in terms of image contrast for all blood volume fractions considered in the simulation. Additionally, better results can be obtained also with respect to the case of CA administration only. Results from model simulations demonstrate the effectiveness of masking techniques to improve image contrast regarding all vessel sizes of clinical interest in the high resolution susceptibility-based brain venography possibly avoiding, in some cases, the need for CA administration.
{"title":"Model simulations and comparative evaluations of susceptibility-based and gadolinium contrast enhancement for high-resolution brain venography","authors":"E. Casciaro, R. Franchini, F. Conversano, P. Pisani, S. Casciaro, A. Lay-Ekuakille","doi":"10.1109/MeMeA.2016.7533729","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533729","url":null,"abstract":"The MRI signal, in terms of amplitude and phase, was simulated for susceptibility-based brain venography (BV) without and with administration of contrast agent (CA) under standard clinical parameters and field magnitude of 1.5 T (Tesla). Then, in order to compare the enhancement due to CA and that one obtained through susceptibility weighted magnitude image (SWI) processing, exploiting only the intrinsic magnetic susceptibility differences between blood and surrounding tissue, the simulated signal was processed with a well-known phase masking technique to increase signal differences as a function of tissue type, thus generating better image contrast. The simulation was carried out adopting a well-established bi-compartmental model, described by a set of analytical formulas. The based simulated signal was processed with the SWI technique considering a conventional masking procedure available in literature and a different masking method designed and described in our previous work. The resulting enhanced signals in terms of image contrast obtained with these two different phase masking procedures and with the administration of conventional CA were compared. The new designed mask (DM), compared with the conventional one, allows to get better results in terms of image contrast for all blood volume fractions considered in the simulation. Additionally, better results can be obtained also with respect to the case of CA administration only. Results from model simulations demonstrate the effectiveness of masking techniques to improve image contrast regarding all vessel sizes of clinical interest in the high resolution susceptibility-based brain venography possibly avoiding, in some cases, the need for CA administration.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132913828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533722
F. Orsini, A. Scorza, A. Rossi, F. Botta, S. Sciuto, R. D. Giminiani
Over the last decade, many studies have been conducted on the effects of mechanical vibration on the physical hormonal and neuromuscular responses of muscles: in some works the growth hormone response showed a dependence on the acceleration provided by Whole Body Vibration (WBV) platforms with respect to subjects responsiveness. Therefore the accuracy of acceleration measurements related to the excitation system is important and should be assessed. To this aim a preliminary study on the identification and evaluation of the measurement uncertainty sources in the measurement chain of a novel WBV platform developed by the Authors is here proposed. After the main measurement error sources have been identified, a Monte Carlo simulation Method has been implemented to obtain the uncertainty in accelerations and displacements provided by the WBV platform. Since main causes of uncertainty has been identified in the accelerometer sensitivity, its mounting and the data acquisition processing, Results of the test showed a relative uncertainty of about ±4% for acceleration and displacement measurements for frequencies between 20Hz and 60Hz.
{"title":"A preliminary uncertainty analysis of acceleration and displacement measurements on a novel WBV platform for biologic response studies","authors":"F. Orsini, A. Scorza, A. Rossi, F. Botta, S. Sciuto, R. D. Giminiani","doi":"10.1109/MeMeA.2016.7533722","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533722","url":null,"abstract":"Over the last decade, many studies have been conducted on the effects of mechanical vibration on the physical hormonal and neuromuscular responses of muscles: in some works the growth hormone response showed a dependence on the acceleration provided by Whole Body Vibration (WBV) platforms with respect to subjects responsiveness. Therefore the accuracy of acceleration measurements related to the excitation system is important and should be assessed. To this aim a preliminary study on the identification and evaluation of the measurement uncertainty sources in the measurement chain of a novel WBV platform developed by the Authors is here proposed. After the main measurement error sources have been identified, a Monte Carlo simulation Method has been implemented to obtain the uncertainty in accelerations and displacements provided by the WBV platform. Since main causes of uncertainty has been identified in the accelerometer sensitivity, its mounting and the data acquisition processing, Results of the test showed a relative uncertainty of about ±4% for acceleration and displacement measurements for frequencies between 20Hz and 60Hz.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"177 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132841601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}