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2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)最新文献

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A novel approach to evaluate blood parameters using computer vision techniques 一种利用计算机视觉技术评估血液参数的新方法
Pub Date : 2016-05-15 DOI: 10.1109/MEMEA.2016.7533760
Vitoantonio Bevilacqua, G. Dimauro, F. Marino, Antonio Brunetti, Fabio Cassano, Antonio Di Maio, Enrico Nasca, Gianpaolo Francesco Trotta, Francesco Girardi, A. Ostuni, A. Guarini
Current medical practice for determining hemoglobin concentration (which is especially important for anemic patients in need of blood transfusion) involves frequent blood tests. In this work, we propose an alternative, non-invasive approach to hemoglobin estimation, based on image analysis of a specific conjunctival region. Our ultimate goal is to develop an easy-to-use wearable device that patients themselves can employ at home to autonomously assess their need of blood transfusion. In this paper, we detail the prototype of our device and the methodology for extracting key information from the color values of the acquired image. Tests conducted on 77 anemic and healthy patients show significant correlation between the real hemoglobin value obtained through blood sampling and the value estimated by our algorithm. A prototypical binary classification algorithm for assessing the need of blood transfusion yielded good results in terms of accuracy, specificity and sensitivity, thus making it possible to avoid a significant number of blood tests.
目前确定血红蛋白浓度(这对需要输血的贫血患者尤其重要)的医疗实践包括频繁的血液检查。在这项工作中,我们提出了一种替代的,非侵入性的血红蛋白估计方法,基于特定结膜区域的图像分析。我们的最终目标是开发一种易于使用的可穿戴设备,病人自己可以在家里使用,以自主评估他们的输血需求。在本文中,我们详细介绍了我们的设备的原型和从采集图像的颜色值中提取关键信息的方法。对77例健康和贫血患者的测试表明,通过采血获得的真实血红蛋白值与我们的算法估算值之间存在显著相关性。用于评估输血需求的一种原型二元分类算法在准确性、特异性和敏感性方面取得了良好的结果,从而有可能避免大量血液检查。
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引用次数: 44
Response to stress in the parents of children with autism spectrum disorder 自闭症谱系障碍儿童父母对压力的反应
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533781
E. Pattini, D. Rollo
Literature on the subject hints that the skills of parents with children affected by autism are different from those of parents whose children with typical development or affected by other conditions. Among parental characteristics empathy and reciprocity in the child-parent relationship helps to bring to surface the child's social skills, learning adaptability and has a crucial influence on mental development along the entire lifespan. This research was aimed to investigate the differences about coping and empathy in mothers of children (3-11 years-old) divided in two groups: an “ASD group” consisting of mothers of children diagnosed with autism spectrum disorder and a “control group” including mothers of children with typical development.
有关这一主题的文献表明,患有自闭症的孩子的父母的技能与患有正常发育或其他疾病的孩子的父母的技能不同。在父母特征中,亲子关系中的共情和互惠有助于孩子的社交技能、学习适应性的显现,并对整个生命周期的心理发展产生重要影响。本研究旨在探讨3-11岁儿童的母亲在应对和共情方面的差异:“ASD组”由诊断为自闭症谱系障碍的儿童的母亲组成,“对照组”由发育正常的儿童的母亲组成。
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引用次数: 3
Falls in older adults: Kinematic analyses with a crash test dummy 老年人跌倒:碰撞试验假人的运动学分析
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533759
M. Tarabini, B. Saggin, M. Bocciolone, D. Scaccabarozzi, Marianna Magni
Falls have always been a frequent and complex problem that might cause fatality, morbidity, loss or damage of body functions and undesired health care needs. The problem is relevant especially for senior citizens and different studies focused on systems for fall detections. This work analyzes the fall kinematics by means of accelerometers placed on head and torso of a crush test dummy used for fall simulations. This configuration reflects the situation in which the subject does not have any voluntary reaction to possible injuries, which is similar to what occurs during elder people fall. Accelerations were measured upon varying the dummy posture; data obtained from accelerometers were compared with those measured with a vision system. The comparison was based on both the peak velocity and on the fall duration. Results showed the compatibility between the data measured with the two methods, outlining the possibility of identifying the peak velocity from videos available on the internet captured, for instance by video surveillance cameras.
跌倒一直是一个频繁而复杂的问题,可能导致死亡、发病率、身体功能丧失或损害以及不期望的卫生保健需求。这个问题与老年人尤其相关,不同的研究都集中在跌倒检测系统上。这项工作通过放置在头部和躯干的加速度计来分析坠落运动学,用于坠落模拟的粉碎试验假人。这种结构反映了受试者对可能的伤害没有任何自愿反应的情况,这与老年人摔倒时发生的情况类似。在改变假人姿势时测量加速度;将加速度计获得的数据与视觉系统测量的数据进行比较。对比是基于峰值速度和下落持续时间。结果显示了用两种方法测量的数据之间的兼容性,概述了从互联网上可用的视频中识别峰值速度的可能性,例如通过视频监控摄像头。
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引用次数: 5
SmartCED: An Android application for neonatal seizures detection SmartCED:用于新生儿癫痫检测的Android应用程序
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533708
L. Cattani, H. Saini, G. Ferrari, F. Pisani, R. Raheli
In this paper, we present Smartphone-based Contactless Epilepsy Detector (SmartCED): an Android monitoring application able to diagnose neonatal clonic seizures and warn about their possible occurrences in realtime. SmartCED has, however, wider applicability so that it could also be used on adult patients. The main goal is to implement a wire-free and low-cost epilepsy diagnostic system, executing all the necessary processing directly on the smartphone. Seizures' recognition is based on a well-known statistical criterion, namely Maximum Likelihood (ML). As clonic seizures are characterized by quasi-periodic movements of some body parts, it is possible to detect the presence of a seizure by evaluating this periodicity from the video stream of the smartphone's camera. The heavy computational processing is carried out in the native code (C language) to enhance the performance. SmartCED presents a user-friendly interface in order to extend its use even to unskilled staff. In fact, although it integrates complex software from the technical point of view, the user has just to: start the App, “frame the patient”, and start monitoring with a simple touch.
在本文中,我们介绍了基于智能手机的非接触式癫痫检测器(SmartCED):一种Android监测应用程序,能够诊断新生儿慢性癫痫发作并实时警告其可能发生的情况。然而,SmartCED具有更广泛的适用性,因此它也可以用于成人患者。主要目标是实现一个无线和低成本的癫痫诊断系统,直接在智能手机上执行所有必要的处理。癫痫发作的识别是基于一个众所周知的统计标准,即最大似然(ML)。由于慢性癫痫发作的特征是某些身体部位的准周期性运动,因此可以通过智能手机摄像头的视频流评估这种周期性来检测癫痫发作的存在。大量的计算处理在本机代码(C语言)中进行,以提高性能。SmartCED提供了一个用户友好的界面,以便将其扩展到不熟练的员工。事实上,虽然从技术角度来看,它集成了复杂的软件,但用户只需要:启动应用程序,“框架病人”,并通过简单的触摸开始监测。
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引用次数: 5
Characterizing the non-linear elastic properties of ex-vivo mouse tissues 表征离体小鼠组织的非线性弹性特性
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533816
Ramona De Luca, E. Rizzuto, Z. Prete
Elastography imaging is a promising technique to non-invasively assess the mechanical properties of biological tissues. Characterization of the non-linear elastic behavior of soft tissues represents a promising challenge in this field. The strain hardening effect of tissues with the increase of the applied load is already known, but up to today, few quantitative data of this effect exist in literature. This study aimed at revealing the elastic properties of ex-vivo mouse tissues and at characterizing their non-linear elastic behavior. This was done using a dedicated indentation experimental system that measured the length of each sample under a controlled force. Three mouse tissue specimens were studied: a Tibialis Anterior (TA) muscle, an Extensor Digitorum Longus (EDL) muscle and an adipose tissue sample. The investigation of the stress-strain curve reconstructed from experimental data revealed that TA, EDL and fat tissues showed a linear elasticity for strains up to 3.05%, 8.2% and 9.2% respectively. The non-linear region of the curve was found to be exponential, showing that TA muscle exhibited a strain hardening effect higher than EDL muscle and adipose tissue. The present study provided biomechanical models allowing to estimate the Young's modulus of the specimens as a function of the strains at a specific stress profile. Our preliminary results suggest the validity of these models in describing the non-linear stress-strain relationship of tissues. This allows a proper interpretation of elastograms obtained through large compression and/or pre-compression and helps in preventing misdiagnosis. Further investigations are needed to confirm this preliminary evidence.
弹性成像技术是非侵入性评估生物组织力学特性的一种很有前途的技术。表征的非线性弹性行为的软组织是一个有希望的挑战,在这一领域。随着外加载荷的增加,组织的应变硬化效应已经为人所知,但迄今为止,文献中很少有这种效应的定量数据。本研究旨在揭示小鼠离体组织的弹性特性,并对其非线性弹性行为进行表征。这是通过专用的压痕实验系统完成的,该系统在受控力下测量每个样品的长度。研究了三种小鼠组织样本:胫骨前肌(TA)、指长伸肌(EDL)和脂肪组织样本。根据实验数据重构的应力应变曲线研究表明,TA、EDL和脂肪组织对应变的线性弹性分别高达3.05%、8.2%和9.2%。曲线的非线性区域呈指数型,表明TA肌肉的应变硬化效应高于EDL肌肉和脂肪组织。本研究提供了生物力学模型,可以估计样品的杨氏模量作为特定应力剖面下应变的函数。我们的初步结果表明,这些模型在描述组织的非线性应力-应变关系方面是有效的。这允许正确解释通过大压缩和/或预压缩获得的弹性图,并有助于防止误诊。需要进一步调查以证实这一初步证据。
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引用次数: 1
Difficulties in reading and neuropsychological profile on WISC-IVin Italian children 意大利儿童WISC-IVin的阅读困难和神经心理特征
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533782
D. Petretto, P. Piras, Ilenia Pistis, Elena Tradori, M. Camboni, Federica Staico, F. Palmas, Carla Lussu, A. Preti, C. Masala
Since the born of intelligence tests, there have been a debate about the praticai use of intelligence tests, also with a lots of critics about the nature and the data we can derive from them. Perhaps the study of intelligence tests could be divided in different historical steps, in newer steps intelligence test were used and analyzed according to more detailed psychometrical bases and aiming to define specific profiles and to design specific intervention according to thus specific profiles. In current step, the single general index IQ is maintained but there is also a deeper analysis of single indexes and macroindexes according to a theorical framework. Wechsler Intelligence Scales are one of the worldwide more utilized tests for the assessment of general reasoning abilities and cognitive profile in children. In the last 20 years the CHC Model from Cattell-Horn and Carrol is the worldwide more utilized theoretical model for the analysis of abilities related to intelligence and pattern derived from intelligence test, supported by a great number of datasets. The interpretation of WISC-IV scores, based on CHC (Carrol-Horn-Cattell) model of intelligence, permit to evaluate single cognitive functions and to assess general reasoning competence as well as to describe verbal reasoning, visual spatial reasoning, working memory and speed of processing. New diagnostic criteria for dyslexia and for specific learning disabilities on reading from DSM-5 no more considered discrepancy criteria (a discrepancy between IQ and scores on reading test), but the assessment of neuropsychological profile and cognitive profile by intelligence test and other neuropsychological tests of the child remains an important phase of clinical evaluation ((1), (2), (3)). Different studies analyzed performance on WISC test in children with reading disorders from different countries (for example in France and Portugal), using different versions of the instrument (Wisc-r, Wisc-III, Wisc-IV) ((4), (5), (6) (7)) and also according to different criteria of selection (see (8) for persistent academic difficulties). The question about a dyslexic profile on the test is still open, perhaps due to different methodological choices in the different researches and to the use of different versions of Wechsler Scale for Children test. Purpose of this article is to describe performance on Wisc-IV test in Italian children, based on CHC model and to make a deeper analysis of cognitive profile, on single test level, and on indexes level. 168 children in the study were consecutively referred to the authors due to persistent academic difficulties and we selected 90 who have persistent difficulties related to reading (specific o unspecific) (from January 2013 to may 2014). Data on cognitive profile on single test level, and on indexes level are discussed, based on CHC model. Clinical issues are proposed, also aiming to the creation on personalized intervention, also in school.
自从智力测验诞生以来,关于智力测验的实际应用一直存在争论,对智力测验的性质和我们可以从中获得的数据也有很多批评。也许智力测验的研究可以分为不同的历史阶段,在新的阶段,智力测验是根据更详细的心理测量学基础来使用和分析的,旨在定义特定的概况,并根据这些特定的概况设计特定的干预措施。当前阶段,在保持单项总体指标智商的基础上,对单项指标和宏观指标进行了较为深入的理论分析。韦氏智力量表是目前世界上比较常用的儿童一般推理能力和认知能力评估量表之一。在过去的20年里,cattel - horn和carroll提出的CHC模型是世界范围内使用较多的理论模型,用于分析与智力相关的能力和智力测试的模式,得到了大量数据集的支持。对WISC-IV分数的解释,基于CHC (carol - horn - cattell)智力模型,允许评估单一认知功能,评估一般推理能力,以及描述语言推理,视觉空间推理,工作记忆和处理速度。DSM-5中关于阅读障碍和特殊学习障碍的新诊断标准不再考虑差异标准(IQ和阅读测试分数之间的差异),但通过智力测试和其他神经心理测试对儿童的神经心理特征和认知特征的评估仍然是临床评估的重要阶段((1),(2),(3))。不同的研究分析了来自不同国家(例如法国和葡萄牙)的阅读障碍儿童在WISC测试中的表现,使用不同版本的工具(WISC -r, WISC - iii, WISC - iv)((4),(5),(6)(7)),并且根据不同的选择标准(见(8)对于持续学习困难)。关于测试中阅读障碍的问题仍然是开放的,可能是由于不同研究中不同的方法选择以及使用不同版本的韦氏儿童测试量表。本文的目的是描述意大利儿童在Wisc-IV测试中的表现,基于CHC模型,在认知概况、单测试水平和指标水平上进行更深入的分析。本研究中有168名儿童因持续学习困难而被连续转诊给作者,我们选择了90名患有持续阅读困难的儿童(具体的或非具体的)(2013年1月至2014年5月)。在CHC模型的基础上,讨论了单测试水平和指标水平上的认知概况数据。临床问题的提出,也旨在对个性化干预的创造,也在学校。
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引用次数: 0
EEG signal processing and acquisition for detecting abnormalities via bio-implantable devices 利用生物植入装置检测异常的脑电图信号处理与采集
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533752
A. Lay-Ekuakille, G. Griffo, F. Conversano, S. Casciaro, A. Massaro, V. Bhateja, F. Spano
The proposed research illustrates an innovating implantable micro-apparatus to be encompassed under the scalp for monitoring and retrieving electrical cerebral activities. The illustrated system considers its theoretical realization including, design of circuital electronic components and energy harvesting, 3D package, chemical aspects concerning the utilization of UHMWPE (Ultra High Molecular Weight Polyethylene) polymeric materials for packaging including mechanical simulations and comparison with titanium material, and electromagnetic aspects regarding the Wi-Fi radiation. A full description of necessary circuitry is included. Moreover, for chemical viewpoint, requirements of polymeric nanomaterials, embedding silver or copper nanoparticles to be used for its fabrication, are discussed illustrating antibacterial and electromagnetic wall barrier properties. The study of the proposed work concerns the whole design of the system.
本研究提出了一种创新的植入式微型装置,该装置将被包裹在头皮下,用于监测和检索脑电活动。所述系统考虑了其理论实现,包括电路电子元件和能量收集的设计,3D封装,化学方面关于使用超高分子量聚乙烯(超高分子量聚乙烯)聚合物材料进行封装,包括机械模拟和与钛材料的比较,以及电磁方面关于Wi-Fi辐射。包括必要电路的完整描述。此外,从化学的角度出发,讨论了聚合物纳米材料的要求,即嵌入银或铜纳米颗粒用于其制造,说明了抗菌和电磁壁阻隔性能。本文的研究涉及到整个系统的设计。
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引用次数: 10
An integrated system to compensate for temperature drift and ageing in non-invasive blood pressure measurement 在无创血压测量中补偿温度漂移和老化的集成系统
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533751
Huthaifa N. Abderahman, H. Dajani, M. Bolic, V. Groza
Accurate blood pressure (BP) measurement is critical in the diagnosis and management of hypertension, as an error of 5 mmHg can be responsible for doubling or halving the number of patients diagnosed with this condition. Sensor drift, due to changing environmental factors, such as ambient temperature, can contribute to the inaccuracy. Studies also show that long term sensor drift, or ageing, can lead to a change of almost 9 mmHg in blood pressure measurement during the first three months of usage. In this work, a new stage is added to current cuff-based BP devices. This stage is responsible for adjusting the pressure reading before displaying it to end users, by monitoring changes in the ambient temperature and sensor ageing and adaptively compensating for these inaccuracies. These sources of inaccuracy are suppressed using algorithms based on Empirical Mode Decomposition (EMD), which has the feature of removing unwanted noise components without affecting the phase or the frequency distribution of the measured signal.
准确的血压(BP)测量对于高血压的诊断和治疗至关重要,因为5毫米汞柱的误差可能导致诊断为高血压的患者数量增加一倍或减半。由于环境因素(如环境温度)的变化,传感器漂移会导致不准确。研究还表明,长期的传感器漂移或老化,可能导致在使用的前三个月血压测量值变化近9毫米汞柱。在这项工作中,为现有的套管式BP设备增加了一个新的阶段。这个阶段负责在显示给最终用户之前调整压力读数,通过监测环境温度和传感器老化的变化,并自适应地补偿这些不准确性。使用基于经验模态分解(EMD)的算法抑制这些不准确源,该算法具有去除不需要的噪声成分而不影响被测信号的相位或频率分布的特点。
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引用次数: 4
Robust wireless capacitive ECG system with adaptive signal quality and motion artifact reduction 具有自适应信号质量和运动伪影抑制的鲁棒无线电容心电系统
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533802
I. Castro, R. Morariu, T. Torfs, C. Hoof, R. Puers
A robust wireless system for capacitive ECG is presented, which measures electrode-body capacitive impedance, acceleration, and gyroscope signals from the electrodes to be used in motion artifact reduction algorithms. The system dynamically adapts its robustness and signal quality according to the environmental conditions. Optimizations including bias resistance and cancellation of common mode signals are discussed, and an office chair implementation is presented. An example of motion artifact compensation by means of an adaptive filter that uses the recorded signals is shown; and the dynamic adaptation to prevent front-end saturation is demonstrated and validated.
提出了一种鲁棒的容性心电无线系统,该系统测量电极-体电容阻抗、加速度和陀螺仪信号,用于运动伪迹减少算法。系统根据环境条件动态调整鲁棒性和信号质量。讨论了包括偏置电阻和共模信号对消在内的优化,并给出了办公椅的实现。示出了利用所记录信号的自适应滤波器进行运动伪影补偿的示例;并对防止前端饱和的动态自适应进行了论证和验证。
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引用次数: 21
Two-electrode bioelectrical impedance measurement in body composition analysis before and after liposuction 双电极生物电阻抗测量在吸脂前后体成分分析中的应用
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533701
N. I. Khramtsova, S. Plaksin
Background: The aim of the study was to determine the diagnostic value of bioelectrical impedance analysis in estimating the components of human body in dynamics. Subjects/Methods: The objects of the research were 37 healthy women before and after water-jet liposuction. Bioelectrical impedance analysis (BIA) was provided with portable non-professional analyzer “Tanita BC-542”. Subcutaneous adipose tissue, body water, muscle and bone components, and basal metabolism degree were obtained. Results: The body weight significantly increased immediately after liposuction, and on the 7th day it returned to the initial, body weight growth was associated with massive infusion during surgery. The percentage of fat, obtained with BIA, slightly decreased immediately after liposuction and significantly decreased on the 7th day. There is a correlation of the change in body fat percentage with the amount of the removed adipose tissue immediately after surgery and on the 7th day after surgery. The volume of the removed fat correlated with fat changes revealed by BIA immediately after surgery and on the 7th day. Body water, obtained with BIA, increased non-significantly immediately after liposuction, and significantly on the 7th day. Changes in weight after liposuction correlated with the difference between infused and aspirated fluid. Conclusions: Two-electrode BIA is an informative, accurate, easy to perform and affordable method of determining body mass, body fat and water percentage. Fatty tissue percentage and body water measured by BIA correlates with the volumes of removed fat and infused water.
背景:本研究的目的是确定生物电阻抗分析在估计人体动力学成分方面的诊断价值。对象/方法:选取健康女性37例,进行水射流抽脂术前后对照。生物阻抗分析(BIA)采用便携式非专业分析仪“Tanita BC-542”。测定皮下脂肪组织、体内水分、肌肉和骨骼成分及基础代谢程度。结果:吸脂后体重立即明显增加,第7天恢复到初始水平,体重增长与术中大量输注有关。BIA获得的脂肪百分比在吸脂后立即略有下降,并在第7天显著下降。体脂百分比的变化与术后即刻和术后第7天切除脂肪组织的量呈正相关。术后即刻及第7天BIA显示的脂肪变化与移除脂肪的体积相关。用BIA获得的体水在吸脂后立即增加,但在第7天显著增加。吸脂后体重的变化与输注和抽吸液体的差异相关。结论:双电极BIA是一种信息丰富、准确、操作简便、价格合理的测定体重、体脂和水百分比的方法。BIA测量的脂肪组织百分比和体水与去除脂肪和注入水的体积相关。
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引用次数: 1
期刊
2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
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