More than 100 different HPV genotypes have been recognised and classified into low and high risk. The latter are responsible for a number of anogenital malignancies in both genders. For example, persistent genital infection with HPV 16 or 18, in association with various cofactors (i.e. prolonged Pill use, multiparity, smoking, co-infection with other STIs, etc.), causes cervical cancer 20 to 30 years later. This long latency period, between exposure and disease development, allows for screening to detect precancerous abnormalities. In contrast, the low risk genotypes are mainly associated with benign conditions. For example, HPV 6 and 11 cause genital warts (Condylomata acuminata).
{"title":"Is the human papilloma virus vaccine a good investment","authors":"O. Varsou, Paschalis Kapsomenakis","doi":"10.5580/28ce","DOIUrl":"https://doi.org/10.5580/28ce","url":null,"abstract":"More than 100 different HPV genotypes have been recognised and classified into low and high risk. The latter are responsible for a number of anogenital malignancies in both genders. For example, persistent genital infection with HPV 16 or 18, in association with various cofactors (i.e. prolonged Pill use, multiparity, smoking, co-infection with other STIs, etc.), causes cervical cancer 20 to 30 years later. This long latency period, between exposure and disease development, allows for screening to detect precancerous abnormalities. In contrast, the low risk genotypes are mainly associated with benign conditions. For example, HPV 6 and 11 cause genital warts (Condylomata acuminata).","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85000563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Saravanan, K. Reddy, S. Vivekanandam, V. Parthasarathy, N. Vijayaprabhu, S. Mourougan
Mantle field is used for supradiaphragmatic disease. Determination of absorbed dose for Mantle Field technique by conventional method and direct dosimetry is studied and compared in this paper. For Mantle field, a field size of about or more than 40 X 40cm is usually needed. To obtain a bigger field size it is mandatory to extend the FSD. A change of FSD results in a significant change in Percentage Depth Dose (PDD) and beam out-put. Mayneord factor is used to determine the PDD for extended FSD. The behavior of the PDD at various FSD is studied by mathematical as well as by direct dosimetry method. The absorbed dose is obtained by performing dosimetry at extended FSD using TRS-398 protocol. From the study it is concluded that direct dosimetry is one of the precise method to determine absorbed dose for Mantle Field at Extended FSD.
{"title":"Determination of absorbed dose for Mantle Field with Extended FSD.","authors":"K. Saravanan, K. Reddy, S. Vivekanandam, V. Parthasarathy, N. Vijayaprabhu, S. Mourougan","doi":"10.5580/1dbc","DOIUrl":"https://doi.org/10.5580/1dbc","url":null,"abstract":"Mantle field is used for supradiaphragmatic disease. Determination of absorbed dose for Mantle Field technique by conventional method and direct dosimetry is studied and compared in this paper. For Mantle field, a field size of about or more than 40 X 40cm is usually needed. To obtain a bigger field size it is mandatory to extend the FSD. A change of FSD results in a significant change in Percentage Depth Dose (PDD) and beam out-put. Mayneord factor is used to determine the PDD for extended FSD. The behavior of the PDD at various FSD is studied by mathematical as well as by direct dosimetry method. The absorbed dose is obtained by performing dosimetry at extended FSD using TRS-398 protocol. From the study it is concluded that direct dosimetry is one of the precise method to determine absorbed dose for Mantle Field at Extended FSD.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81234189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Ngom, Dakar Sénégal, A. Ndiaye, O. Ndour, M. Fall, M. Ndoye, G. Ngom, A. Ndiaye, O. Ndour, M. Fall, M. Ndoye
We report an exceptional case of Giant Cell Tumor (GCT) in child. A twelve –year-old girl which presented a tumefaction at the lower extremity of her right leg. The clinical examination revealed a good general state of health, a non inflammatory tumor at the latero-external side of his right leg. A standard X-ray photography showed a bee nest like osteolysis lesion at the lower fibula metaphyse. A biopsy was performed and confirmed the diagnosis of a GCT. The treatment consisted in a large ablation of the tumor including part of the healthy zone, followed by an autologous iliac bone graft, stabilized with a Metaizeau pin and a cruropedal plaster. The evolution was favourable after a period of two years. The case we are presenting is fairly exceptional because of its location and the age of the patient.
{"title":"Giant cell tumors of the child’s fibula: a case study","authors":"G. Ngom, Dakar Sénégal, A. Ndiaye, O. Ndour, M. Fall, M. Ndoye, G. Ngom, A. Ndiaye, O. Ndour, M. Fall, M. Ndoye","doi":"10.5580/137f","DOIUrl":"https://doi.org/10.5580/137f","url":null,"abstract":"We report an exceptional case of Giant Cell Tumor (GCT) in child. A twelve –year-old girl which presented a tumefaction at the lower extremity of her right leg. The clinical examination revealed a good general state of health, a non inflammatory tumor at the latero-external side of his right leg. A standard X-ray photography showed a bee nest like osteolysis lesion at the lower fibula metaphyse. A biopsy was performed and confirmed the diagnosis of a GCT. The treatment consisted in a large ablation of the tumor including part of the healthy zone, followed by an autologous iliac bone graft, stabilized with a Metaizeau pin and a cruropedal plaster. The evolution was favourable after a period of two years. The case we are presenting is fairly exceptional because of its location and the age of the patient.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77488979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Jaggon, K. Bishop, M. Pedican, W. Halliday, R. Melbourne-Chambers, J. Tapper
Atypical teratoid/rhabdoid tumors (AT/RTs) of the central nervous system (CNS) are distinctive, malignant neoplasms of uncertain histogenesis. They are thought to be embryonal and are usually composed of varying amounts of rhabdoid-type cells, small primitive neuroepithelial cells, epithelial tissue and neoplastic mesenchyme. Diagnosis may be difficult due to this morphologic variability and usually depends on demonstrating the presence of a specific mutation on chromosome 22 (the hSNF5/INI1 gene) or by visualizing ultrastructural whorled masses of intracytoplasmic intermediate filaments. The prognosis is poor with the majority of patients dying within one year of diagnosis.We describe a case of an AT/RT in an 8 year old boy who died shortly after presentation and whose tumor at autopsy showed unusual gross and histologic features. Diagnosis was only made after electron microscopy and immunohistochemical stains revealed the characteristic features.
{"title":"Atypical Teratoid/Rhabdoid Tumor: An Unusual Variant of a Rare Entity","authors":"J. Jaggon, K. Bishop, M. Pedican, W. Halliday, R. Melbourne-Chambers, J. Tapper","doi":"10.5580/26d7","DOIUrl":"https://doi.org/10.5580/26d7","url":null,"abstract":"Atypical teratoid/rhabdoid tumors (AT/RTs) of the central nervous system (CNS) are distinctive, malignant neoplasms of uncertain histogenesis. They are thought to be embryonal and are usually composed of varying amounts of rhabdoid-type cells, small primitive neuroepithelial cells, epithelial tissue and neoplastic mesenchyme. Diagnosis may be difficult due to this morphologic variability and usually depends on demonstrating the presence of a specific mutation on chromosome 22 (the hSNF5/INI1 gene) or by visualizing ultrastructural whorled masses of intracytoplasmic intermediate filaments. The prognosis is poor with the majority of patients dying within one year of diagnosis.We describe a case of an AT/RT in an 8 year old boy who died shortly after presentation and whose tumor at autopsy showed unusual gross and histologic features. Diagnosis was only made after electron microscopy and immunohistochemical stains revealed the characteristic features.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79754564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shahi K.S., Pant Nirdosh, V. Gupta, Abhishek Singh
OBJECTIVE – To investigate the tolerance to and response rate with hyperfractionated external radiotherapy in stages IIB to III and postoperative cases of carcinoma uterine cervix.METHODSA prospective study of carcinoma uterine cervix FIGO stage IIB to III and postoperative cases was undertaken. A total of 22 patients were studied (12 in study group and 10 in control group).Control group was treated by conventional fractionation-60Gy/30fractions (f), 2Gy/f, 5days/week for 6 weeks.Study group was treated in hyperfractionation schedule 72Gy/60f,5days/week over 6weeks. Two fractions of 120cGy per day were given at interval of 6 hours.RESULTS – Patients enrolled in this study ,13.6% had stage IIB ,4.5% stage IIIA,22.7% stage IIIB and 59.1% postoperative cases. No severe acute toxicity was observed but moderate acute reactions were high. The commonest site of complication was small bowel where severe toxicity occurred slightly higher in study group than control group. Complete response was 80% and 91.7% in control and study group respectively.CONCLUSION Hyperfractionated radiotherapy as compared to conventional radiotherapy has produced clinically better tumor control in stages IIB to III and postoperative cases without enhancing normal tissue damage.
{"title":"Role of Hyperfactionated external beam radiotherapy in stage IIB to III and postoperative cases of carcinoma cervix: an evaluation","authors":"Shahi K.S., Pant Nirdosh, V. Gupta, Abhishek Singh","doi":"10.5580/211d","DOIUrl":"https://doi.org/10.5580/211d","url":null,"abstract":"OBJECTIVE – To investigate the tolerance to and response rate with hyperfractionated external radiotherapy in stages IIB to III and postoperative cases of carcinoma uterine cervix.METHODSA prospective study of carcinoma uterine cervix FIGO stage IIB to III and postoperative cases was undertaken. A total of 22 patients were studied (12 in study group and 10 in control group).Control group was treated by conventional fractionation-60Gy/30fractions (f), 2Gy/f, 5days/week for 6 weeks.Study group was treated in hyperfractionation schedule 72Gy/60f,5days/week over 6weeks. Two fractions of 120cGy per day were given at interval of 6 hours.RESULTS – Patients enrolled in this study ,13.6% had stage IIB ,4.5% stage IIIA,22.7% stage IIIB and 59.1% postoperative cases. No severe acute toxicity was observed but moderate acute reactions were high. The commonest site of complication was small bowel where severe toxicity occurred slightly higher in study group than control group. Complete response was 80% and 91.7% in control and study group respectively.CONCLUSION Hyperfractionated radiotherapy as compared to conventional radiotherapy has produced clinically better tumor control in stages IIB to III and postoperative cases without enhancing normal tissue damage.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91528819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Casanova, Jesús R.C. Lizazo, S. Shezi, F. Oliver
Melanoma is the most dangerous type of skin cancer. It is the leading cause of death from skin disease. It involves cells called melanocytes, which produce a skin pigment called melanin. Melanin is responsible for skin and hair colour.Melanoma can also involve the colour part of the eye. Although it is less common than other types of skin cancer, the rate of melanoma is steadily increasing. Melanoma may appear on normal skin, or it may begin at a mole or other area that has changed in appearance. The development of melanoma is related to sun exposure, particularly to sunburns during childhood, and is most common among people with fair skin, blue or green eyes, and red or blond hair. Unlike these previous facts, the authors have been treated during the last 3year seven patients all of them from Zulu ethnic. Here the authors present a 61 years old female patient who
{"title":"Right Inguinal Bowel Fistula On The Course Of Melanoma Disease","authors":"F. Casanova, Jesús R.C. Lizazo, S. Shezi, F. Oliver","doi":"10.5580/1a1","DOIUrl":"https://doi.org/10.5580/1a1","url":null,"abstract":"Melanoma is the most dangerous type of skin cancer. It is the leading cause of death from skin disease. It involves cells called melanocytes, which produce a skin pigment called melanin. Melanin is responsible for skin and hair colour.Melanoma can also involve the colour part of the eye. Although it is less common than other types of skin cancer, the rate of melanoma is steadily increasing. Melanoma may appear on normal skin, or it may begin at a mole or other area that has changed in appearance. The development of melanoma is related to sun exposure, particularly to sunburns during childhood, and is most common among people with fair skin, blue or green eyes, and red or blond hair. Unlike these previous facts, the authors have been treated during the last 3year seven patients all of them from Zulu ethnic. Here the authors present a 61 years old female patient who","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87568383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bhuvana Sagar, Fadi Estaphan, D. W. Spell, F. Klementich, Dennie V. Jones
Carboplatin forms the backbone of many regimens for nonsmall cell lung cancer (NSCLC). 5-fluorouracil (5-FU) is modestly active in NSCLC and is synergistic with platinum analogs. This trial evaluated the activity and toxicity of capecitabine, an oral 5FU prodrug, with carboplatin in patients with unresectable NSCLC. Eligibility criteria included untreated measurable stage IIIB/IV NSCLC, ECOG performance status < 2, and adequate organ function. Carboplatin, AUC=5, was administered on day one, with capecitabine, 4000 mg days 1-14, every 28 days. Tumor assessments were obtained every other cycle. Fifteen patients (median age = 64; median performance status = 0) were enrolled and received 46 cycles of protocol therapy; 13 were evaluable for response, with 5 partial responses (38.5%). Five withdrew due to toxicity; four possibly related to study therapy. Median survival was 8 months. Capecitabine and carboplatin are active in NSCLC. Further investigation is not warranted, as this current regimen is too toxic.
{"title":"A Pilot Phase Ii Study Of Capecitabine With Carboplatin In Patients With Advanced Nonsmall Cell Lung Cancer","authors":"Bhuvana Sagar, Fadi Estaphan, D. W. Spell, F. Klementich, Dennie V. Jones","doi":"10.5580/1d6e","DOIUrl":"https://doi.org/10.5580/1d6e","url":null,"abstract":"Carboplatin forms the backbone of many regimens for nonsmall cell lung cancer (NSCLC). 5-fluorouracil (5-FU) is modestly active in NSCLC and is synergistic with platinum analogs. This trial evaluated the activity and toxicity of capecitabine, an oral 5FU prodrug, with carboplatin in patients with unresectable NSCLC. Eligibility criteria included untreated measurable stage IIIB/IV NSCLC, ECOG performance status < 2, and adequate organ function. Carboplatin, AUC=5, was administered on day one, with capecitabine, 4000 mg days 1-14, every 28 days. Tumor assessments were obtained every other cycle. Fifteen patients (median age = 64; median performance status = 0) were enrolled and received 46 cycles of protocol therapy; 13 were evaluable for response, with 5 partial responses (38.5%). Five withdrew due to toxicity; four possibly related to study therapy. Median survival was 8 months. Capecitabine and carboplatin are active in NSCLC. Further investigation is not warranted, as this current regimen is too toxic.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82663272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Shukla, Pronati Gupta, D. Gupta, M. Pant, N. Husain, S. Bisht
Leiomyosarcoma account for 5-10% of soft tissue sarcomas1. They are principally tumors of adult life and are more common in women than in men. Primary oral leiomyosarcoma is a rare entity with unusual bone location because of paucity of smooth muscle in that site2. We report a histologically proven case of leiomyosarcoma of maxilla with bilateral renal metastasis, which were visualized in CT and diagnosed by CT guided fine needle aspiration cytology (FNA).
{"title":"Oral Leiomyosarcoma With Bilateral Renal Metastases In A Pregnant Female: A Case Report","authors":"P. Shukla, Pronati Gupta, D. Gupta, M. Pant, N. Husain, S. Bisht","doi":"10.5580/17ba","DOIUrl":"https://doi.org/10.5580/17ba","url":null,"abstract":"Leiomyosarcoma account for 5-10% of soft tissue sarcomas1. They are principally tumors of adult life and are more common in women than in men. Primary oral leiomyosarcoma is a rare entity with unusual bone location because of paucity of smooth muscle in that site2. We report a histologically proven case of leiomyosarcoma of maxilla with bilateral renal metastasis, which were visualized in CT and diagnosed by CT guided fine needle aspiration cytology (FNA).","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80555843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Tran, V. Asfour, P. ChangChin-Yung, Osman Ahmedfiqi
Clear cell sarcoma (CCS) is aggressive, slow growing tumor, arising from tendons, aponeuroses, and fascial structures. CCS compromises only 1% of soft tissue sarcomas. CCS is characterized by a high rate of local recurrence and distant metastasis. CCS is commonly located in extremities, and less likely to arise in the trunk with only rare cases found in pelvis or abdomen. Here we describe a case of clear cell sarcoma, in which it develops from the iliac wing with distant pulmonary and liver metastasis. We discuss and review the clinicopathologic features of CCS include: structural and microscopic characteristics, prognosis factors, management, and outcome.
{"title":"Clear cell sarcoma arising from the iliac wing: case report","authors":"H. Tran, V. Asfour, P. ChangChin-Yung, Osman Ahmedfiqi","doi":"10.5580/24a4","DOIUrl":"https://doi.org/10.5580/24a4","url":null,"abstract":"Clear cell sarcoma (CCS) is aggressive, slow growing tumor, arising from tendons, aponeuroses, and fascial structures. CCS compromises only 1% of soft tissue sarcomas. CCS is characterized by a high rate of local recurrence and distant metastasis. CCS is commonly located in extremities, and less likely to arise in the trunk with only rare cases found in pelvis or abdomen. Here we describe a case of clear cell sarcoma, in which it develops from the iliac wing with distant pulmonary and liver metastasis. We discuss and review the clinicopathologic features of CCS include: structural and microscopic characteristics, prognosis factors, management, and outcome.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81300242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Kadikoy, W. Haque, V. Topkara, A. Frome, T. Hayes
We describe an unusual case of bilateral renal leiomyosarcoma in a 61-year-old white man in a patient who presented with a pulmonary emoblism. The patient also had an uncle with bilateral kidney cancer. The patient did not undergo surgery, as the tumor had invaded the surrounding vasculature and was felt to be unresectable by the consulting surgeons. He was treated with gemcitabine and docetaxel chemotherapy, with stabilization of disease. Patient is now stable 10 months after beginning therapy. Sarcomas make up 1–2% of all malignant renal tumors in adult. Bilateral renal leiomyosarcomas are exceedingly rare, with only 17 being reported in the literature. To the best of our knowledge, this is the first reported case of bilateral renal leiomyosarcoma with a family history of bilateral renal cancer.
{"title":"Bilateral Leiomyosarcoma Of The Kidney With Family History Of Bilateral Kidney Cancer: Case Report And Review Of The Literature","authors":"H. Kadikoy, W. Haque, V. Topkara, A. Frome, T. Hayes","doi":"10.5580/187f","DOIUrl":"https://doi.org/10.5580/187f","url":null,"abstract":"We describe an unusual case of bilateral renal leiomyosarcoma in a 61-year-old white man in a patient who presented with a pulmonary emoblism. The patient also had an uncle with bilateral kidney cancer. The patient did not undergo surgery, as the tumor had invaded the surrounding vasculature and was felt to be unresectable by the consulting surgeons. He was treated with gemcitabine and docetaxel chemotherapy, with stabilization of disease. Patient is now stable 10 months after beginning therapy. Sarcomas make up 1–2% of all malignant renal tumors in adult. Bilateral renal leiomyosarcomas are exceedingly rare, with only 17 being reported in the literature. To the best of our knowledge, this is the first reported case of bilateral renal leiomyosarcoma with a family history of bilateral renal cancer.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91435871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}