The evaluation and treatment of the internal mammary nodes (IMNs) in patients with axillary node positive breast cancer undergoing breast conservation therapy is somewhat controversial. A recently reported randomized trial of radiation therapy to the local regional nodes (including the IMNs) in patients undergoing breast conservation therapy demonstrated an improvement in disease free survival and overall survival with this additional nodal irradiation. For patients with tumors in the medial quadrants of the breast, consideration of peritumoral sentinel lymph node procedures with or without periareolar injections should be considered as demonstrated lymphatic drainage to the IMNs may indicate a greater need to consider their inclusion in adjuvant radiation therapy fields, regardless of clinical or radiographic involvement. These nodes may be treated either with a separate IMN field or partially-wide tangents. The benefits of this inclusion must be weighed against the risks of side effects of increased radiation exposure of lung, heart and contralateral breast tissue. Additional long-term data from randomized trials currently underway and maturing may help to define the risks versus the benefits of IMN elective nodal irradiation
{"title":"Internal Mammary Node Evaluation And Elective Nodal Treatment In Medial Breast Cancers: A Case Report And Review Of The Literature.","authors":"E. Miles, C. Cinnamond, C. Allgeier, J. Nelson","doi":"10.5580/2adc","DOIUrl":"https://doi.org/10.5580/2adc","url":null,"abstract":"The evaluation and treatment of the internal mammary nodes (IMNs) in patients with axillary node positive breast cancer undergoing breast conservation therapy is somewhat controversial. A recently reported randomized trial of radiation therapy to the local regional nodes (including the IMNs) in patients undergoing breast conservation therapy demonstrated an improvement in disease free survival and overall survival with this additional nodal irradiation. For patients with tumors in the medial quadrants of the breast, consideration of peritumoral sentinel lymph node procedures with or without periareolar injections should be considered as demonstrated lymphatic drainage to the IMNs may indicate a greater need to consider their inclusion in adjuvant radiation therapy fields, regardless of clinical or radiographic involvement. These nodes may be treated either with a separate IMN field or partially-wide tangents. The benefits of this inclusion must be weighed against the risks of side effects of increased radiation exposure of lung, heart and contralateral breast tissue. Additional long-term data from randomized trials currently underway and maturing may help to define the risks versus the benefits of IMN elective nodal irradiation","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78687774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashwin Pai, H. S. Ram, T. Sarkar, S. Bhat, Ashfaque Mohammed
Adenocarcinoma of the rete testis is a rare tumour with a varied presentation. A total of 44 cases have been reported [1]. Of these testicular tumours, primary non germ cell tumours account for a minority of cases.Among this, adenocarcinoma originating in the rete testis is still rarer. It is a highly malignant tumour with poor prognosis. It is generally diagnosed clinically as a solid or cystic swelling. However, confirmation is madeonly on histological diagnosis.
{"title":"Adenocarcinoma Of The Rete Testis With Secondaries In The Skin – Review Of Literature And Case Report","authors":"Ashwin Pai, H. S. Ram, T. Sarkar, S. Bhat, Ashfaque Mohammed","doi":"10.5580/2a8c","DOIUrl":"https://doi.org/10.5580/2a8c","url":null,"abstract":"Adenocarcinoma of the rete testis is a rare tumour with a varied presentation. A total of 44 cases have been reported [1]. Of these testicular tumours, primary non germ cell tumours account for a minority of cases.Among this, adenocarcinoma originating in the rete testis is still rarer. It is a highly malignant tumour with poor prognosis. It is generally diagnosed clinically as a solid or cystic swelling. However, confirmation is madeonly on histological diagnosis.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87413749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The cause of ovarian cancers is not known but the most common risk factor is a positive family history of ovarian or breast cancer. Primary tumors of the ovaries may arise from the epithelium (82%), sex cord and germ cell (20%) areas. About 3-5% of all germ cell tumors (GCTs) are malignant with the most common being the dysgerminoma which also accounts for 4-5% of all ovarian cancers. Dysgerminomas are most commonly seen in women of reproductive age who are sexually active and they make up to 60% of all malignant ovarian tumors in women younger than 20 years. We present a rare case of ovarian dysgerminoma in a 58-year old post menopausal woman who, presented to the gynecological unit of a secondary health care center in Makurdi, Nigeria. She had staging laparotomy and cytoreductive surgery. Initial chemotherapy with bleomycin, etoposide and cisplatin showed a good response. The appearance of this cancer in this age group should be a reminder to practitioners of the need to develop effective screening methods for ovarian cancers and the sensitization of patients to present early while attempts are made to open up well equipped cancer treatment centers, with adequately trained personnel. This is important since, ovarian cancers are the second most common gynecological malignancies and have the highest case fatality world wide; but once diagnosed dysgerminomas respond well to treatment.
{"title":"A Rare Case Of Dysgerminoma In A 58-Year Old Postmenopausal Woman In Makurdi, North Central Nigeria.","authors":"Hembah-Hilekaan Sk, M. Tp","doi":"10.5580/2a8b","DOIUrl":"https://doi.org/10.5580/2a8b","url":null,"abstract":"The cause of ovarian cancers is not known but the most common risk factor is a positive family history of ovarian or breast cancer. Primary tumors of the ovaries may arise from the epithelium (82%), sex cord and germ cell (20%) areas. About 3-5% of all germ cell tumors (GCTs) are malignant with the most common being the dysgerminoma which also accounts for 4-5% of all ovarian cancers. Dysgerminomas are most commonly seen in women of reproductive age who are sexually active and they make up to 60% of all malignant ovarian tumors in women younger than 20 years. We present a rare case of ovarian dysgerminoma in a 58-year old post menopausal woman who, presented to the gynecological unit of a secondary health care center in Makurdi, Nigeria. She had staging laparotomy and cytoreductive surgery. Initial chemotherapy with bleomycin, etoposide and cisplatin showed a good response. The appearance of this cancer in this age group should be a reminder to practitioners of the need to develop effective screening methods for ovarian cancers and the sensitization of patients to present early while attempts are made to open up well equipped cancer treatment centers, with adequately trained personnel. This is important since, ovarian cancers are the second most common gynecological malignancies and have the highest case fatality world wide; but once diagnosed dysgerminomas respond well to treatment.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85092472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung cancer is the leading cause of cancer death in the United States, with an estimated 222,500 new cases diagnosed in 2010; non-small cell lung cancer (NSCLC) accounted for approximately 85% of these malignancies. Treatment for early stage NSCLC in an operable patient involves lobar resection. Thoracic aortic aneurysms form as a result of exposure to smoking, hypertension, atherosclerosis, and genetic connective tissue disorders. The literature is silent on the optimum course of action when the anatomic lobar resection for NSCLC is limited by a thoracic aortic aneurysm, particularly when a close surgical margin indicates consideration of adjuvant radiation therapy. Although there is some literature documenting the radiation injury pattern to intact great blood vessels, the literature is silent on the potential for further injury to the wall of the great vessels in the presence of an existing aneurysm. With the increase in the use of definitive stereotactic body radiotherapy for early stage NSCLC in medically inoperable patients, there is a potential for an increased risk of vascular injury secondary to radiation in patients whose vessels already have baseline atherosclerotic damage. Herein, we report a case of a patient diagnosed with wedge-resected early stage NSCLC with close margin in the immediate vicinity of a pre-existing large thoracic aortic aneurysm.
{"title":"Adjuvant Radiation Therapy For Wedge-Resected Non-Small Cell Lung Cancer Adjacent To A Large Thoracic Aortic Aneurysm: A Case Report And Review Of The Literature","authors":"C. E. Miles, C. Strange","doi":"10.5580/2a8a","DOIUrl":"https://doi.org/10.5580/2a8a","url":null,"abstract":"Lung cancer is the leading cause of cancer death in the United States, with an estimated 222,500 new cases diagnosed in 2010; non-small cell lung cancer (NSCLC) accounted for approximately 85% of these malignancies. Treatment for early stage NSCLC in an operable patient involves lobar resection. Thoracic aortic aneurysms form as a result of exposure to smoking, hypertension, atherosclerosis, and genetic connective tissue disorders. The literature is silent on the optimum course of action when the anatomic lobar resection for NSCLC is limited by a thoracic aortic aneurysm, particularly when a close surgical margin indicates consideration of adjuvant radiation therapy. Although there is some literature documenting the radiation injury pattern to intact great blood vessels, the literature is silent on the potential for further injury to the wall of the great vessels in the presence of an existing aneurysm. With the increase in the use of definitive stereotactic body radiotherapy for early stage NSCLC in medically inoperable patients, there is a potential for an increased risk of vascular injury secondary to radiation in patients whose vessels already have baseline atherosclerotic damage. Herein, we report a case of a patient diagnosed with wedge-resected early stage NSCLC with close margin in the immediate vicinity of a pre-existing large thoracic aortic aneurysm.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80325204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Toprak, S. Ocal, B. Erismis, E. Yıldırım, R. Altun, S. Karakuş, I. Tek, P. Topçuoğlu
Background/Aims: The frequency of drug-related gastrointestinal adverse effects, including pancreatitis, has increased with the development and use of chemotherapeutic agents. Methods: In our country, a combination of vincristine, doxorubicin, and dexamethasone is frequently used as the first line of therapy in newly diagnosed multiple myeloma. A case with acute pancreatitis that we believe to depend on this therapy is presented. Results: In this case, after treatment of the acute pancreatitis episode in a very dynamic process, a proteasome inhibitor and following high dose chemotherapy with melphalan were used for the primary disease. Currently the patient is under follow-up at remission. Conclusion: It is important to consider chemotherapeutic agents as a possible etiology for acute pancreatitis in patients presenting with gastrointestinal symptoms, even after a few exposures to the agent.
{"title":"Acute Pancreatitis Following VAD Chemotherapy Combination Consisting Of Vincristine, Doxorubicin, And Dexamethasone In A Newly Diagnosed Multiple Myeloma Patient: A Case Report.","authors":"S. Toprak, S. Ocal, B. Erismis, E. Yıldırım, R. Altun, S. Karakuş, I. Tek, P. Topçuoğlu","doi":"10.5580/2b68","DOIUrl":"https://doi.org/10.5580/2b68","url":null,"abstract":"Background/Aims: The frequency of drug-related gastrointestinal adverse effects, including pancreatitis, has increased with the development and use of chemotherapeutic agents. Methods: In our country, a combination of vincristine, doxorubicin, and dexamethasone is frequently used as the first line of therapy in newly diagnosed multiple myeloma. A case with acute pancreatitis that we believe to depend on this therapy is presented. Results: In this case, after treatment of the acute pancreatitis episode in a very dynamic process, a proteasome inhibitor and following high dose chemotherapy with melphalan were used for the primary disease. Currently the patient is under follow-up at remission. Conclusion: It is important to consider chemotherapeutic agents as a possible etiology for acute pancreatitis in patients presenting with gastrointestinal symptoms, even after a few exposures to the agent.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80586674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Distant metastases from colon cancer spread most frequently to the liver and the lung. Risk factors include positive lymph nodes and high grade tumors.Colorectal cancer is the 3 leading cause of cancer related death in the world. Death is usually associated with recurrence and metastasis. Skeletal metastasis in primary colorectal carcinoma is an uncommon event. When such an event occurs it is usually a late manifestation of the disease. Isolated skeletal metastasis from primary colonic carcinoma is a rare event with incidence of 1.1% of all metastases from colonic cancers . The most common presenting symptom of skull metastases is a visible, localized swelling of skull produced by growing tumor that erodes outer table. Metastasis to bone gives rise to osteolysis or mixed osteolysis – osteoblastic appearance on radiography.
{"title":"A Rare Case Of Colon Cancer With Metastases To The Bone With Review Of The Literature","authors":"J. Rodrigues, A. Ramani, N. Mitta, P. Joshi","doi":"10.5580/2c4e","DOIUrl":"https://doi.org/10.5580/2c4e","url":null,"abstract":"Distant metastases from colon cancer spread most frequently to the liver and the lung. Risk factors include positive lymph nodes and high grade tumors.Colorectal cancer is the 3 leading cause of cancer related death in the world. Death is usually associated with recurrence and metastasis. Skeletal metastasis in primary colorectal carcinoma is an uncommon event. When such an event occurs it is usually a late manifestation of the disease. Isolated skeletal metastasis from primary colonic carcinoma is a rare event with incidence of 1.1% of all metastases from colonic cancers . The most common presenting symptom of skull metastases is a visible, localized swelling of skull produced by growing tumor that erodes outer table. Metastasis to bone gives rise to osteolysis or mixed osteolysis – osteoblastic appearance on radiography.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88600573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Khanna, D. Nayak, C. Manohar, N. Suvarna, S. Belurkar, S. Ray, P. Srilatha
Rhabdomyosarcoma is the most common soft tissue sarcoma in children and adolescents. In adults, the prevalence is much lower. Most patients present with a mass in the head and neck region, urogenital region or even with distal extremity involvement. A bone marrow infiltration at the time of clinical presentation has also been documented in literature. But a simultaneous marrow infiltration can simulate a hematopoietic neoplasm, leading to diagnostic errors. We document one such challenging case of a 47 year old male patient presenting with bicytopenia. Patient was hospitalized following a referral due to a mass in the left cheek, diagnosed earlier as clear cell sarcoma. Bone marrow aspirates yielded a dry tap, with sinusoidal blood and both the aspirate as well as the imprint smear showed pleomorphic cells with vacuolated cytoplasm. The corresponding trephine biopsy showed diffuse and interstitial infiltrates of rhabdoid cells with focal areas of infarct. Considering the morphological details, a diagnosis of rhabdomyosarcoma was rendered after ruling out other possibilities. A review of the lesional biopsy with ancillary techniques eventually corroborated the bone marrow diagnosis.
{"title":"Rhabdomyosarcoma with Bone Marrow Infiltration: A Diagnostic Dilemma","authors":"R. Khanna, D. Nayak, C. Manohar, N. Suvarna, S. Belurkar, S. Ray, P. Srilatha","doi":"10.5580/2a8d","DOIUrl":"https://doi.org/10.5580/2a8d","url":null,"abstract":"Rhabdomyosarcoma is the most common soft tissue sarcoma in children and adolescents. In adults, the prevalence is much lower. Most patients present with a mass in the head and neck region, urogenital region or even with distal extremity involvement. A bone marrow infiltration at the time of clinical presentation has also been documented in literature. But a simultaneous marrow infiltration can simulate a hematopoietic neoplasm, leading to diagnostic errors. We document one such challenging case of a 47 year old male patient presenting with bicytopenia. Patient was hospitalized following a referral due to a mass in the left cheek, diagnosed earlier as clear cell sarcoma. Bone marrow aspirates yielded a dry tap, with sinusoidal blood and both the aspirate as well as the imprint smear showed pleomorphic cells with vacuolated cytoplasm. The corresponding trephine biopsy showed diffuse and interstitial infiltrates of rhabdoid cells with focal areas of infarct. Considering the morphological details, a diagnosis of rhabdomyosarcoma was rendered after ruling out other possibilities. A review of the lesional biopsy with ancillary techniques eventually corroborated the bone marrow diagnosis.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86592814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Vagholkar, Indumati Gopinathan, Shalini Nair, Siddartha Nachane, O. Joglekar, Amogh Vaishampayan
Dermatofibrosarcoma protuberans is a slow growing deceptive tumor. It is a low grade malignancy with potential to develop local recurrence as well as metastases especially to the lungs. Surgery is the mainstay of treatment. Neoadjuvant therapy is a useful adjunct in large and recurrent tumors. Molecular targeting with imatinib mesylate is a promising option. Optimum neoadjuvant therapy followed by Moh’s micrographic surgery is the best therapeutic modality with least morbidity and mortality. A case of recurrent dermatofibrosarcoma protuberans is presented along with a review of literature.
{"title":"Dermatofibrosarcoma Protuberans: A Deceptive Neoplasm.","authors":"K. Vagholkar, Indumati Gopinathan, Shalini Nair, Siddartha Nachane, O. Joglekar, Amogh Vaishampayan","doi":"10.5580/2b53","DOIUrl":"https://doi.org/10.5580/2b53","url":null,"abstract":"Dermatofibrosarcoma protuberans is a slow growing deceptive tumor. It is a low grade malignancy with potential to develop local recurrence as well as metastases especially to the lungs. Surgery is the mainstay of treatment. Neoadjuvant therapy is a useful adjunct in large and recurrent tumors. Molecular targeting with imatinib mesylate is a promising option. Optimum neoadjuvant therapy followed by Moh’s micrographic surgery is the best therapeutic modality with least morbidity and mortality. A case of recurrent dermatofibrosarcoma protuberans is presented along with a review of literature.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72905220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Majority of the prostate malignancies are adenocarcinoma in nature. Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% -3.7% of primary prostate malignancies. Prostate sarcomas are diagnostically and therapeutically very challenging. This neoplasm is a mesenchymal tumor that originates from smooth muscles of prostate and periprostatic tissue. We present a patient with primary leiomyosarcoma of the prostate and review of literature. The factors predictive of long-term survival are negative surgical margins and absence of metastatic disease at presentation. A multidisciplinary approach is necessary for appropriate management of this rare entity. The most effective treatment, if feasible, is radical surgery. The role of adjuvant treatments and their effects in terms of increasing local control, over all survival or disease free survival is not clearly defined in literature.
{"title":"Prostatic Leiomyosarcoma –A Rare Case Report With Review Of Literature","authors":"A. Dubey, G. Sivananthan, T. Bradel, R. Koul","doi":"10.5580/195d","DOIUrl":"https://doi.org/10.5580/195d","url":null,"abstract":"Majority of the prostate malignancies are adenocarcinoma in nature. Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% -3.7% of primary prostate malignancies. Prostate sarcomas are diagnostically and therapeutically very challenging. This neoplasm is a mesenchymal tumor that originates from smooth muscles of prostate and periprostatic tissue. We present a patient with primary leiomyosarcoma of the prostate and review of literature. The factors predictive of long-term survival are negative surgical margins and absence of metastatic disease at presentation. A multidisciplinary approach is necessary for appropriate management of this rare entity. The most effective treatment, if feasible, is radical surgery. The role of adjuvant treatments and their effects in terms of increasing local control, over all survival or disease free survival is not clearly defined in literature.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78294490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Back ground: Total abdominal hysterectomy (TAH) is a commonly performed surgical procedure by many doctors in the developing world, for reasons ranging from mild benign to severe malignant conditions. This is because they are often confronted with cases where treatment has to be offered to their patients either due to lack of facilities and / or personnel for appropriate diagnosis or pressure and anxiety from clients and relatives, resulting in cases of undiagnosed cervical malignancy. Many of which could have been treated differently if properly diagnosed.Objective: This study was to evaluate the uterine specimen obtained after TAH and bilateral salpingo-oopherectomy (BSO) for undiagnosed cervical bleeding for unexpected histology.Design/ methods: This was a retrospective study design. The case of a 58-year old woman with post coital bleeding who was anxious to have hysterectomy for fear of cervical cancer was analyzed after surgery with the histology report of the surgical (TAH/BSO) specimen .Result: She had TAH/BSO with excision of a cuff of the vagina. The histology of the specimen showed evidence of early locally invasive cancer of the cervix. The surgical margins were microscopically disease free. She was referred for radiotherapy at a regional centre in Nigeria (Ibadan) where she had teletherapy and two years of outpatient followup showed no recurrence or complications.Conclusion: Cases of invasive cervical cancer usually present late in this part of the world with surgical treatment not considered an option. We present a case of undiagnosed early cervical cancer in a postmenopausal woman who had successful TAH/BSO and postoperative radiotherapy. Preventive screening measures coupled with accurate diagnosis, and the improvement in manpower and facilities have been known to give better results. This is a reminder to all doctors and gynecologists of the need for cervical screening, in our hospitals.
{"title":"Undiagnosed Cervical Cancer After Total Abdominal Hysterectomy In North Central Nigeria-Case Report","authors":"S. Hembah-Hilekaan, J. Kigbu","doi":"10.5580/1eff","DOIUrl":"https://doi.org/10.5580/1eff","url":null,"abstract":"Back ground: Total abdominal hysterectomy (TAH) is a commonly performed surgical procedure by many doctors in the developing world, for reasons ranging from mild benign to severe malignant conditions. This is because they are often confronted with cases where treatment has to be offered to their patients either due to lack of facilities and / or personnel for appropriate diagnosis or pressure and anxiety from clients and relatives, resulting in cases of undiagnosed cervical malignancy. Many of which could have been treated differently if properly diagnosed.Objective: This study was to evaluate the uterine specimen obtained after TAH and bilateral salpingo-oopherectomy (BSO) for undiagnosed cervical bleeding for unexpected histology.Design/ methods: This was a retrospective study design. The case of a 58-year old woman with post coital bleeding who was anxious to have hysterectomy for fear of cervical cancer was analyzed after surgery with the histology report of the surgical (TAH/BSO) specimen .Result: She had TAH/BSO with excision of a cuff of the vagina. The histology of the specimen showed evidence of early locally invasive cancer of the cervix. The surgical margins were microscopically disease free. She was referred for radiotherapy at a regional centre in Nigeria (Ibadan) where she had teletherapy and two years of outpatient followup showed no recurrence or complications.Conclusion: Cases of invasive cervical cancer usually present late in this part of the world with surgical treatment not considered an option. We present a case of undiagnosed early cervical cancer in a postmenopausal woman who had successful TAH/BSO and postoperative radiotherapy. Preventive screening measures coupled with accurate diagnosis, and the improvement in manpower and facilities have been known to give better results. This is a reminder to all doctors and gynecologists of the need for cervical screening, in our hospitals.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89957774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：