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Practice patterns in reporting and documentation of Charles Bonnet syndrome: a retrospective review following COVID-19. 报告和记录查尔斯-邦奈特综合征的实践模式:COVID-19 之后的回顾性研究。
IF 2.5 Q2 OPHTHALMOLOGY Pub Date : 2024-03-27 eCollection Date: 2024-01-01 DOI: 10.1177/25158414241232285
Dalia Abdulhussein, Lee Jones, Sri Harsha Dintakurti, Mariya Moosajee

Background: Charles Bonnet syndrome (CBS) is characterized by visual hallucinations occurring in people with visual impairment. CBS can negatively impact psychological well-being, and the COVID-19 pandemic period was associated with an exacerbation of symptoms.

Objectives: To compare clinical practice patterns and reporting of CBS at a tertiary eye care center between an interval prior to the COVID-19 pandemic and an interval during the pandemic.

Design: Retrospective chart review.

Methods: A search of electronic medical records for all suspected CBS cases was conducted between 1 March 2019 and 29 February 2020 (prior pandemic interval) and between 1 September 2020 and 29 August 2021 (peri-pandemic interval). Data retrieved from records included patient demographics, visual acuity at the time of CBS onset, type of hallucinations, reporting healthcare professional, management strategies and patient-reported impact of hallucinations.

Results: In total, 223 appointments referred to CBS in 156 patients at the prior interval, while 239 appointments referred to CBS in 155 patients at the peri-pandemic interval, representing 0.07% and 0.09% of all hospital attendance, respectively. Clinical subspecialty where CBS was most commonly reported was medical retina, and a greater proportion of patients at both time intervals were female. Types of hallucinations, management strategies and patient-reported impact were seldom reported, although documentation improved at the latter interval.

Conclusion: Practice patterns and patient characteristics were similar between the two intervals; however, subtle differences suggest a growing awareness of CBS. Targeted interventions in high-burden clinical subspecialties may encourage reporting and improve documentation of CBS.

背景:查尔斯-波奈综合征(CBS)的特征是视力受损者出现视幻觉。CBS 可对心理健康产生负面影响,COVID-19 大流行期间症状加剧:目的:比较一家三级眼科医疗中心在 COVID-19 大流行前和大流行期间的临床实践模式和 CBS 报告情况:设计:回顾性病历审查:方法:对2019年3月1日至2020年2月29日(大流行前)和2020年9月1日至2021年8月29日(大流行期间)期间所有疑似CBS病例的电子病历进行检索。从记录中检索到的数据包括患者人口统计学特征、CBS发病时的视力、幻觉类型、报告的医护人员、管理策略以及患者报告的幻觉影响:在之前的间歇期,共有156名患者的223次就诊涉及CBS,而在围大流行期间,共有155名患者的239次就诊涉及CBS,分别占所有就诊人数的0.07%和0.09%。最常报告 CBS 的临床亚专科是内科视网膜,两个时间段中女性患者的比例都较高。幻觉的类型、处理策略和患者报告的影响很少被报告,尽管在后一个时间段记录的情况有所改善:结论:两个时间段的实践模式和患者特征相似;但细微的差异表明,人们对 CBS 的认识在不断提高。在高负担临床亚专科采取有针对性的干预措施可鼓励报告并改善 CBS 的记录。
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引用次数: 0
A unique late-onset intraocular lens opacification 23 years after implantation: a clinical and laboratory case report. 眼内晶状体植入 23 年后出现独特的晚发性眼内晶状体混浊:临床和实验室病例报告。
IF 2.5 Q2 OPHTHALMOLOGY Pub Date : 2024-03-25 eCollection Date: 2024-01-01 DOI: 10.1177/25158414241237713
Panos S Gartaganis, Panagiota D Natsi, Sotirios P Gartaganis, Petros G Koutsoukos, Horst Helbig

We report an unusual, rare case of opacification of the hydrophilic acrylic intraocular lens (IOL) 23 years after the initial surgery with significant visual deterioration. Opacification of the hydrophilic acrylic IOL was primarily due to the formation of folds on the surface of the lens material, and less so due to calcium phosphate deposits. Calcification opacification can be attributed to recent events, as evidenced by deposits of dicalcium phosphate dihydrate (CaHPO42H2O) and octacalcium phosphate (Ca8H2(PO4)65H2O), both of which are transient calcium phosphate phases, converting hydrolytically to the thermodynamically most stable hydroxyapatite (Ca10(PO4)6(OH)2). To our knowledge, this case of hydrophilic acrylic IOL opacification is the only one that has been described so late, 23 years after cataract surgery.

我们报告了一例不寻常的罕见病例,患者在初次手术后 23 年,亲水性丙烯酸人工晶体(IOL)发生了混浊,视力严重下降。亲水性丙烯酸人工晶体的不透明主要是由于晶状体材料表面褶皱的形成,较少是由于磷酸钙沉积。钙化不透明可归因于近期发生的事件,二水磷酸二钙(CaHPO42H2O)和磷酸八钙(Ca8H2(PO4)65H2O)的沉积就是证明,这两种磷酸钙都是瞬时磷酸钙相,会水解转化为热力学上最稳定的羟基磷灰石(Ca10(PO4)6(OH)2)。据我们所知,这例亲水性丙烯酸人工晶体不透明是唯一一例在白内障手术后 23 年才出现的不透明病例。
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引用次数: 0
Pediatric corneal transplantation: techniques, challenges, and outcomes. 小儿角膜移植:技术、挑战和结果。
IF 2.5 Q2 OPHTHALMOLOGY Pub Date : 2024-03-25 eCollection Date: 2024-01-01 DOI: 10.1177/25158414241237906
Bharat Gurnani, Kirandeep Kaur, Sameer Chaudhary, Ruminder Preet Kaur, Swatishree Nayak, Deepak Mishra, Harinikrishna Balakrishnan, Rohit Om Parkash, Arvind Kumar Morya, Amit Porwal

Pediatric corneal transplant is a highly demanding and technically challenging procedure for the cornea surgeon in today's era. These cases pose unique challenges in clinical and surgical management. The indications of pediatric corneal transplant can be therapeutic, tectonic, optical, and cosmetic. Pediatric patients undergoing corneal transplants are at a high risk of graft infection, failure, rejection, dehiscence, and amblyopia due to young age, robust immune system, increased incidence of trauma, and compliance issues. The other factors contributing to graft failure can be allograft rejection, secondary glaucoma, corneal vascularization, multiple surgeries, vitreous prolapse, and lack of treatment compliance. A successful corneal transplant in children depends on meticulous preoperative evaluation, uneventful surgery, the expertise of a corneal surgeon, and regular and timely postoperative follow-up. Therapeutic and optical penetrating keratoplasty are the most commonly performed transplants in children. However, with the advancements in surgical technique and management protocol, the current focus has shifted toward lamellar keratoplasty. Lamellar keratoplasty offers early visual recovery and potentially fewer complications. Visual rehabilitation through corneal transplant in otherwise blind eyes can be a boon for the children. Recently, keratoprostheses have been promising in children with multiple graft failures. The current review gives insights into epidemiology, etiology, indications, clinical characteristics, investigations, management options, recent advances, and the future of pediatric corneal transplants. As surgical techniques continue to grow and comprehension of pediatric corneal transplants is improving, we can safeguard these eyes with the best possible anatomical and functional outcomes.

对于当今时代的角膜外科医生来说,小儿角膜移植是一项要求极高、技术难度极大的手术。这些病例给临床和手术管理带来了独特的挑战。小儿角膜移植的适应症包括治疗性、构造性、光学性和美容性。接受角膜移植手术的小儿患者由于年龄小、免疫系统强健、外伤发生率增加以及依从性问题,发生移植感染、失败、排斥、裂开和弱视的风险很高。导致移植失败的其他因素包括异体移植排斥反应、继发性青光眼、角膜血管化、多次手术、玻璃体脱垂以及治疗不规范。儿童角膜移植手术的成功取决于细致的术前评估、顺利的手术、角膜外科医生的专业知识以及定期和及时的术后随访。治疗性角膜移植术和光学穿透性角膜移植术是最常见的儿童角膜移植术。不过,随着手术技术和管理方案的进步,目前的重点已转向板层角膜移植术。板层角膜移植术能尽早恢复视力,并可能减少并发症。通过角膜移植手术让原本失明的眼睛恢复视力,对儿童来说是一大福音。最近,角膜塑形术在多次移植失败的儿童中大有可为。本综述将对流行病学、病因学、适应症、临床特征、调查、管理方案、最新进展以及小儿角膜移植的未来进行深入探讨。随着手术技术的不断发展和对小儿角膜移植手术理解的不断提高,我们可以保障这些眼睛获得最佳的解剖和功能效果。
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引用次数: 0
Keratoconus: exploring fundamentals and future perspectives - a comprehensive systematic review. 角膜塑形镜:探索基本原理和未来展望--全面系统综述。
IF 2.5 Q2 OPHTHALMOLOGY Pub Date : 2024-03-20 eCollection Date: 2024-01-01 DOI: 10.1177/25158414241232258
Sana Niazi, Zisis Gatzioufas, Farideh Doroodgar, Oliver Findl, Alireza Baradaran-Rafii, Jacob Liechty, Majid Moshirfar

Background: New developments in artificial intelligence, particularly with promising results in early detection and management of keratoconus, have favorably altered the natural history of the disease over the last few decades. Features of artificial intelligence in different machine such as anterior segment optical coherence tomography, and femtosecond laser technique have improved safety, precision, effectiveness, and predictability of treatment modalities of keratoconus (from contact lenses to keratoplasty techniques). These options ingrained in artificial intelligence are already underway and allow ophthalmologist to approach disease in the most non-invasive way.

Objectives: This study comprehensively describes all of the treatment modalities of keratoconus considering machine learning strategies.

Design: A multidimensional comprehensive systematic narrative review.

Data sources and methods: A comprehensive search was done in the five main electronic databases (PubMed, Scopus, Web of Science, Embase, and Cochrane), without language and time or type of study restrictions. Afterward, eligible articles were selected by screening the titles and abstracts based on main mesh keywords. For potentially eligible articles, the full text was also reviewed.

Results: Artificial intelligence demonstrates promise in keratoconus diagnosis and clinical management, spanning early detection (especially in subclinical cases), preoperative screening, postoperative ectasia prediction after keratorefractive surgery, and guiding surgical decisions. The majority of studies employed a solitary machine learning algorithm, whereas minor studies assessed multiple algorithms that evaluated the association of various keratoconus staging and management strategies. Last but not least, AI has proven effective in guiding the implantation of intracorneal ring segments in keratoconus corneas and predicting surgical outcomes.

Conclusion: The efficient and widespread clinical translation of machine learning models in keratoconus management is a crucial goal of potential future approaches to better visual performance in keratoconus patients.

Trial registration: The article has been registered through PROSPERO, an international database of prospectively registered systematic reviews, with the ID: CRD42022319338.

背景:人工智能的新发展,尤其是在角膜病的早期检测和管理方面取得的可喜成果,在过去几十年中已有利地改变了角膜病的自然病史。人工智能在不同机器(如前节光学相干断层扫描和飞秒激光技术)中的应用提高了角膜病治疗方法(从隐形眼镜到角膜成形技术)的安全性、精确性、有效性和可预测性。这些植入人工智能的方案已经开始实施,眼科医生可以用最无创的方式治疗疾病:本研究全面描述了考虑机器学习策略的所有角膜病治疗方法:设计:多维度综合系统性综述:在五大电子数据库(PubMed、Scopus、Web of Science、Embase 和 Cochrane)中进行了全面检索,无语言、时间或研究类型限制。然后,根据主要网状关键词筛选标题和摘要,选出符合条件的文章。对于可能符合条件的文章,还对全文进行了审查:人工智能在角膜病诊断和临床管理方面大有可为,包括早期检测(尤其是亚临床病例)、术前筛查、角膜屈光手术后异位预测以及指导手术决策。大多数研究采用了一种单独的机器学习算法,而少数研究则评估了多种算法,这些算法评估了各种角膜病分期和管理策略之间的关联。最后但并非最不重要的一点是,人工智能在指导角膜内环节段植入角膜和预测手术结果方面被证明是有效的:机器学习模型在角膜病管理中的高效和广泛的临床应用,是未来改善角膜病患者视觉表现的潜在方法的重要目标:该文章已在PROSPERO(前瞻性注册系统综述的国际数据库)注册,ID为CRD42022319338。
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引用次数: 0
Early recurrence of macular schisis in X-linked retinoschisis treated with vitrectomy for rhegmatogenous retinal detachment under silicone oil: case report and brief literature review. 在硅油条件下对流变性视网膜脱离行玻璃体切割术治疗的 X 连锁视网膜裂孔症黄斑裂孔早期复发:病例报告和简要文献综述。
IF 2.5 Q2 OPHTHALMOLOGY Pub Date : 2024-02-24 eCollection Date: 2024-01-01 DOI: 10.1177/25158414241232261
Panagiotis Stavrakas, Foteini Tsapardoni, Efthymios Karmiris, Ioannis Iatropoulos, Konstantinos Kounas, Spyridon Lygeros, Vassilios Kozobolis, Demetrios G Vavvas

X-linked retinoschisis (XLRS) is an inherited retinal degeneration affecting males, characterized by splitting of the retinal layers. We herein present the outcomes of surgical treatment in a case of XLRS complicated by rhegmatogenous retinal detachment (RRD). A 22-year-old male presented to the emergency department due to decreased visual acuity and visual field defect in his left eye Oculus Sinister (OS) of 1 week duration. The patient reported an early onset retinal degeneration and decreased visual acuity in both eyes since childhood in his past ocular history. Upon presentation, best corrected visual acuity (BCVA) was 6/30 on the right eye Oculus Dexter (OD) and 6/120 OS. Fundus examination revealed areas of peripheral retinal schisis, and the characteristic spoke wheel pattern on the macula of both eyes. In OS, a temporal RRD involving the macula was identified. The patient underwent surgical treatment with pars plana vitrectomy with internal limiting membrane (ILM) peeling, endolaser, and silicone oil (SO) tamponade. BCVA in OS improved to 6/60 and schistic cavities resolution was observed in the immediate postoperative period. The patient's BCVA further improved to 6/19 at 1 month, as foveal anatomy showed relative improvement. However, there was a rapid reappearance of schisis spaces in the macular area at this point, which was also followed by progressive deterioration of foveal schisis by 3 months post-operatively. The resorption and recurrence of lamellar macular schisis changes after ILM peel and presence of SO, highlights that although XLRS findings can temporarily improve upon surgical intervention, the pathogenetic mechanisms contributing to disease phenotype remain to be elucidated.

X连锁视网膜裂孔症(XLRS)是一种遗传性视网膜变性,男性患者多见,其特点是视网膜层分裂。我们在此介绍一例XLRS并发流变性视网膜脱离(RRD)的手术治疗结果。一名 22 岁的男性因左眼视力下降和视野缺损(Oculus Sinister,OS)而到急诊科就诊,病程 1 周。患者称其过去的眼科病史中,双眼视网膜变性和视力下降自孩提时代就开始了。就诊时,他的右眼最佳矫正视力(BCVA)为 6/30,双眼最佳矫正视力(BCVA)为 6/120。眼底检查发现,双眼视网膜周围均有裂孔,黄斑部有特征性的辐状轮纹。在视网膜手术中,发现了累及黄斑的颞侧 RRD。患者接受了平面玻璃体旁切除术,并进行了内缘膜(ILM)剥离、内激光和硅油(SO)填塞等手术治疗。术后立即观察到OS的BCVA改善至6/60,裂孔消退。术后 1 个月,患者的 BCVA 进一步改善至 6/19,眼窝解剖结构也得到了相对改善。然而,此时黄斑区裂隙又迅速出现,术后 3 个月,眼窝裂隙也逐渐恶化。ILM剥离后片状黄斑裂孔变化的吸收和复发以及SO的存在,突出表明虽然XLRS结果在手术干预后可暂时改善,但导致疾病表型的致病机制仍有待阐明。
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引用次数: 0
Brown syndrome: a literature review. 布朗综合征:文献综述。
IF 2.5 Q2 OPHTHALMOLOGY Pub Date : 2024-02-22 eCollection Date: 2024-01-01 DOI: 10.1177/25158414231222118
Masoud Khorrami-Nejad, Elham Azizi, Farah Fareed Tarik, Mohamad Reza Akbari

The current data on various aspects of Brown syndrome are limited and sporadic. This review provides a coherent and comprehensive review of basic features, etiology, classification, differential diagnosis, and different management strategies of patients with Brown syndrome. In this topical review, PubMed, Scopus, and Google Scholar search engines were searched for papers, published between 1950 and January 2023 based on the keywords of this article. The related articles were collected, summarized, categorized, assessed, concluded, and presented. Brown syndrome is identified by restricted passive and active elevation of the eye in adduction. The condition is divided into congenital and acquired causes. The clinical features result from a restricted motion of the superior oblique tendon sheath through the trochlea while trying to look up in adduction. The newest explanation of the underlying pathophysiology has been explained as the presence of a fibrotic strand in the superior oblique muscle tendon with variable insertion sites which creates various elevation deficits seen in Brown syndrome. The most common clinical features include the presence of an abnormal head posture, V-pattern strabismus, and hypotropia in the primary position. Management of Brown syndrome includes watchful observation, surgical, and non-surgical procedures. Some cases might resolve spontaneously without any intervention; however, some acquired cases might require systemic and/or intra-trochlear steroid administration to treat the underlying causes. Surgical procedures such as superior oblique tenectomy and using a silicon tendon expander are indicated in the presence of hypotropia and significant abnormal head posture in the primary position.

目前有关布朗综合征各方面的数据有限,且多为零星数据。本综述对布朗综合征患者的基本特征、病因、分类、鉴别诊断和不同的管理策略进行了连贯而全面的综述。在这篇专题综述中,根据本文的关键词在 PubMed、Scopus 和 Google Scholar 搜索引擎中搜索了 1950 年至 2023 年 1 月间发表的论文。对相关文章进行了收集、汇总、分类、评估、总结和展示。布朗综合征可通过眼球内收时被动和主动抬高受限而确定。该病分为先天性和后天性两种原因。其临床特征是,当试图在外展时抬头时,上斜肌腱鞘通过踝关节的运动受限。对其潜在病理生理学的最新解释是,上斜肌肌腱中存在纤维化股,插入部位不一,从而造成布朗综合征中出现的各种抬高障碍。最常见的临床特征包括头部姿势异常、V 型斜视和原位肌张力低下。布朗综合征的治疗包括观察、手术和非手术治疗。有些病例可能无需任何干预即可自愈,但有些获得性病例可能需要全身和/或耳蜗内注射类固醇来治疗潜在的病因。手术治疗,如上斜腱膜切除术和使用硅肌腱扩张器,适用于存在低垂和主要体位头部姿势明显异常的病例。
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引用次数: 0
Effect of suprachoroidal triamcinolone on intraocular pressure: a systematic review and meta-analysis. 脉络膜上曲安奈德对眼压的影响:系统回顾和荟萃分析。
IF 2.5 Q2 OPHTHALMOLOGY Pub Date : 2024-02-05 eCollection Date: 2024-01-01 DOI: 10.1177/25158414241228671
Altamash Shahriyar Ghazanfar, Aly Hamza Khowaja, Haroon Tayyab

Background: Triamcinolone acetonide is a synthetic corticosteroid with multiple ocular uses. Like other corticosteroids, it too is associated with ocular side effects such as increased intraocular pressure (IOP), glaucoma and cataracts. Suprachoroidal administration of triamcinolone is hoped to reduce the ocular side effects of the drug, especially rises in IOP. Our systematic review and meta-analysis aims to study this phenomenon.

Objectives: The purpose of this study was to evaluate the effect of suprachoroidal triamcinolone injections on IOP.

Design: Systematic review and meta-analysis.

Methods: We utilized the Medline, Scopus and Cochrane databases for this review. Studies published till June 2023, which fulfilled the eligibility criteria, were included. Studies in the English language with adult participants who were administered suprachoroidal triamcinolone without any concurrent intervention were included, whereas studies that did not report the mean and standard deviation for IOP were excluded. The outcome of interest was IOP at 1, 3 and 6 months post-suprachoroidal triamcinolone injection. IOP values from included studies were extracted onto Review Manager version 5.4 for analysis.

Results: Our search yielded 104 results, from which 22 papers were shortlisted for full-text screening. Finally, 12 studies were included in the analysis. Our analysis suggests a statistically significant increase in IOP in the first month after suprachoroidal triamcinolone injection but no significant differences at 3 and 6 months post-injection as compared to baseline.

Conclusion: Elevated IOP at 1 month post-injection must be considered when using suprachoroidal triamcinolone and adequate safety measures must be taken. However, the absence of a significant rise at 3 and 6 months post-injection indicates that this modality is safer than other existing drug delivery methods.

Trial registration: Registered with the Research Registry with the unique identifying number 'reviewregistry1656.' https://www.researchregistry.com/browse-the-registry#registryofsystematicreviewsmeta-analyses/registryofsystematicreviewsmeta-analysesdetails/648eefe65b6523002995eb21/.

背景:曲安奈德是一种人工合成的皮质类固醇,在眼部有多种用途。与其他皮质类固醇一样,它也与眼部副作用有关,如眼压升高、青光眼和白内障。人们希望通过在脉络膜上注射曲安奈德来减少该药物对眼睛的副作用,尤其是眼压的升高。我们的系统综述和荟萃分析旨在研究这一现象:本研究旨在评估脉络膜上腔注射曲安奈德对眼压的影响:系统综述和荟萃分析:方法:我们利用 Medline、Scopus 和 Cochrane 数据库进行综述。我们纳入了截至 2023 年 6 月发表的符合资格标准的研究。纳入的研究均为英语,且成年参与者均接受了脉络膜上曲安奈德治疗,未同时进行任何干预,而未报告眼压平均值和标准差的研究则被排除在外。研究结果为注射脉络膜上曲安奈德后 1、3 和 6 个月的眼压。将纳入研究的眼压值提取到 Review Manager 5.4 版进行分析:我们的搜索结果共产生 104 篇论文,从中筛选出 22 篇论文进行全文筛选。最后,12 项研究被纳入分析。我们的分析表明,在注射脉络膜上曲安奈德后的第一个月,眼压有统计学意义上的显著升高,但注射后 3 个月和 6 个月与基线相比没有显著差异:结论:在使用脉络膜上腔三苯氧胺时,必须考虑到注射后 1 个月的眼压升高,并采取适当的安全措施。不过,注射后 3 个月和 6 个月的眼压没有明显升高,表明这种方式比其他现有给药方法更安全:已在研究注册中心注册,唯一识别码为 "reviewregistry1656"。https://www.researchregistry.com/browse-the-registry#registryofsystematicreviewsmeta-analyses/registryofsystematicreviewsmeta-analysesdetails/648eefe65b6523002995eb21/。
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引用次数: 0
Factors influencing aqueous flare after cataract surgery and its evaluation with laser flare photometry. 影响白内障手术后眼球耀斑的因素及其激光耀斑测光评估。
IF 2.5 Q2 OPHTHALMOLOGY Pub Date : 2023-12-14 eCollection Date: 2023-01-01 DOI: 10.1177/25158414231204111
Christopher Way, Andrew J Swampillai, Kin Sheng Lim, Mayank A Nanavaty

Despite the refinement of modern cataract surgery, postoperative inflammation still constitutes a substantial amount of visual morbidity worldwide. A surrogate for intraocular inflammation and blood-aqueous barrier breakdown can be objectively quantified by Laser flare photometry (LFP). This review outlines the utility of LFP in assessing the assessment of post-cataract surgery inflammation. It highlights the impact of preoperative pathological states such as uveitis and diabetes, intraoperative techniques, including efficient phacoemulsification and direct comparisons between postoperative anti-inflammatory regimes. There is a large interobserver variation in the subjective flare measurement after cataract surgery and the continued use of LFP amongst other objective, noninvasive measurements of intraocular inflammation, particularly in the further development of cataract surgery, is recommended.

尽管现代白内障手术已日臻完善,但术后炎症仍是全球视力发病率的一个重要因素。激光耀斑光度法(LFP)可以客观地量化眼内炎症和血-水屏障破坏的代用指标。本综述概述了 LFP 在评估白内障术后炎症方面的作用。它强调了葡萄膜炎和糖尿病等术前病理状态、术中技术(包括高效的超声乳化)以及术后抗炎方案之间直接比较的影响。白内障手术后主观耀斑测量的观察者间差异很大,建议继续使用 LFP 和其他客观、无创的眼内炎症测量方法,特别是在白内障手术的进一步发展中。
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引用次数: 0
Central contrast sensitivity perimetry discriminates between glaucomatous and non-glaucomatous eyes. 中央对比敏感度视野法区分青光眼和非青光眼眼睛。
IF 2.5 Q2 OPHTHALMOLOGY Pub Date : 2023-10-30 eCollection Date: 2023-01-01 DOI: 10.1177/25158414231208284
Emmanuel Kwasi Abu, Carl Halladay Abraham, Albert Kofi Dadzie, Enyam Amewuho Morny, Michael Ntodie, Stephen Ocansey, Samuel Abokyi, Andrew Owusu-Ansah, Naa Adjeley Addo, Michael Williams, Asantewaa Aboagye-McCarthy, Godfred Sakyi-Badu, Paa Kwesi Fynn Hope, Peter Osei-Wusu Adueming

Background: Glaucoma is an optic neuropathy which causes irreversible vision loss. Standard perimetry, which is essential for glaucoma diagnosis, can only detect glaucomatous visual filed loss when considerable structural damage has occurred. Contrast sensitivity is one of the visual function tests that is reduced in eyes with glaucoma. It is known to be affected in pre-perimetric stages of glaucoma.

Objective: The objective of this study was to investigate the discriminating ability of central contrast sensitivity perimetry in eyes with and without glaucoma.

Design: The study employed a cross-sectional study design.

Methods: The study participants were made of two groups; eyes diagnosed with glaucoma by an ophthalmologist based on visual field test and optical coherence tomography (OCT) and age- and sex-matched controls who were declared free from glaucoma. Static contrast sensitivity (CS) was measured in the central 10° of visual field using a custom psychophysical test.

Results: There were 45 eyes with glaucoma and 45 age- and sex-matched controls in this study. The static CS in the glaucoma group was significantly reduced in 9 out of the 13 tested locations in the central 10° of the visual field. The mean static CS at 5°, 10°, superior hemifield and inferior hemifield were all significantly reduced in the glaucoma patients compared to the controls.

Conclusion: Static CS measurement is a sensitive approach that can be utilized to aid in the detection of glaucoma. The use of static CS can be adopted in the development of a cost-effective yet sensitive screening tool for the detection of glaucoma.

背景:青光眼是一种导致不可逆视力丧失的视神经病变。标准视野对青光眼诊断至关重要,只有在发生相当大的结构损伤时,才能检测到青光眼的视野损失。对比敏感度是青光眼患者视觉功能测试中降低的一种。众所周知,它在青光眼术前阶段受到影响。目的:本研究的目的是探讨中心对比敏感度视野法对青光眼和非青光眼患者的鉴别能力。设计:本研究采用横断面研究设计。方法:研究参与者分为两组;眼科医生根据视野测试和光学相干断层扫描(OCT)诊断为青光眼的眼睛,以及年龄和性别匹配的对照组,他们被宣布没有青光眼。静态对比敏感度(CS)是使用自定义心理物理测试在中心10°视野中测量的。结果:本研究共有45眼青光眼患者和45名年龄和性别匹配的对照组。青光眼组的静态CS在视野中心10°的13个测试位置中的9个位置显著降低。与对照组相比,青光眼患者在5°、10°、上半视野和下半视野的平均静态CS均显著降低。结论:静态CS测量是一种灵敏的方法,可用于青光眼的检测。静态CS的使用可以用于开发一种成本效益高但敏感的青光眼检测筛查工具。
{"title":"Central contrast sensitivity perimetry discriminates between glaucomatous and non-glaucomatous eyes.","authors":"Emmanuel Kwasi Abu,&nbsp;Carl Halladay Abraham,&nbsp;Albert Kofi Dadzie,&nbsp;Enyam Amewuho Morny,&nbsp;Michael Ntodie,&nbsp;Stephen Ocansey,&nbsp;Samuel Abokyi,&nbsp;Andrew Owusu-Ansah,&nbsp;Naa Adjeley Addo,&nbsp;Michael Williams,&nbsp;Asantewaa Aboagye-McCarthy,&nbsp;Godfred Sakyi-Badu,&nbsp;Paa Kwesi Fynn Hope,&nbsp;Peter Osei-Wusu Adueming","doi":"10.1177/25158414231208284","DOIUrl":"https://doi.org/10.1177/25158414231208284","url":null,"abstract":"<p><strong>Background: </strong>Glaucoma is an optic neuropathy which causes irreversible vision loss. Standard perimetry, which is essential for glaucoma diagnosis, can only detect glaucomatous visual filed loss when considerable structural damage has occurred. Contrast sensitivity is one of the visual function tests that is reduced in eyes with glaucoma. It is known to be affected in pre-perimetric stages of glaucoma.</p><p><strong>Objective: </strong>The objective of this study was to investigate the discriminating ability of central contrast sensitivity perimetry in eyes with and without glaucoma.</p><p><strong>Design: </strong>The study employed a cross-sectional study design.</p><p><strong>Methods: </strong>The study participants were made of two groups; eyes diagnosed with glaucoma by an ophthalmologist based on visual field test and optical coherence tomography (OCT) and age- and sex-matched controls who were declared free from glaucoma. Static contrast sensitivity (CS) was measured in the central 10° of visual field using a custom psychophysical test.</p><p><strong>Results: </strong>There were 45 eyes with glaucoma and 45 age- and sex-matched controls in this study. The static CS in the glaucoma group was significantly reduced in 9 out of the 13 tested locations in the central 10° of the visual field. The mean static CS at 5°, 10°, superior hemifield and inferior hemifield were all significantly reduced in the glaucoma patients compared to the controls.</p><p><strong>Conclusion: </strong>Static CS measurement is a sensitive approach that can be utilized to aid in the detection of glaucoma. The use of static CS can be adopted in the development of a cost-effective yet sensitive screening tool for the detection of glaucoma.</p>","PeriodicalId":23054,"journal":{"name":"Therapeutic Advances in Ophthalmology","volume":"15 ","pages":"25158414231208284"},"PeriodicalIF":2.5,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of pneumatic retinopexy in young adults with rhegmatogenous retinal detachment. 气动视网膜固定术治疗年轻成人孔源性视网膜脱离的疗效。
IF 2.5 Q2 OPHTHALMOLOGY Pub Date : 2023-10-30 eCollection Date: 2023-01-01 DOI: 10.1177/25158414231208279
Zeynep İpekli, Seren Pehlivanoğlu, Özgür Artunay

Background: In young adults with rhegmatogenous retinal detachment, pneumatic retinopexy can be a cost-effective and minimally invasive highly effective method in suitable cases.

Objectives: To evaluate the role of pneumatic retinopexy in the treatment of young adults with rhegmatogenous retinal detachment (RRD) and the factors that may affect the success of pneumatic retinopexy.

Design: Retrospective study.

Methods: The study included 67 eyes of 67 patients aged between 21 and 40 who underwent pneumatic retinopexy (PR) between January 2015 and June 2021 for primary RRD. We retrospectively analyzed the prognostic factors that may affect the success of PR, such as preoperative age, best corrected visual acuity, tear site, lens condition, and axial length.

Results: PR was successful in 61.2% of the patients, whereas 38.8% required secondary surgery. Between the group that had a single surgery (Group 1) and the group that required secondary surgery (Group 2) the tear location, axial length, and volumes of gases used were statistically different (p = 0.04, p < 0.001, and p = 0.02, respectively). There was a significant difference in visual acuity before and after surgery in the group that was successful with a single surgery (Friedman χ2 = 40.051, p < 0.001). There was no significant difference between the two groups in terms of intraocular pressure (p > 0.05), and glaucoma was not observed in the postoperative period.

Conclusion: Since it is a minimally invasive and cost-effective method that provides rapid visual rehabilitation, it can be considered as first-line therapy in young adults who are suitable for PR.

背景:在患有孔源性视网膜脱离的年轻人中,在合适的情况下,气动视网膜固定术是一种成本效益高、微创高效的方法。目的:评价气动视网膜固定术在年轻成人孔源性视网膜脱离(RRD)治疗中的作用,以及可能影响气动视网膜修复成功的因素。设计:回顾性研究。方法:该研究包括67名年龄在21岁至40岁之间的患者的67只眼睛,这些患者在2015年1月至2021年6月期间接受了气动视网膜固定术(PR)治疗原发性RRD。我们回顾性分析了可能影响PR成功的预后因素,如术前年龄、最佳矫正视力、撕裂部位、晶状体状况和轴长。结果:61.2%的患者PR成功,38.8%的患者需要二次手术。在单次手术组(第1组)和需要二次手术的组(第2组)之间,撕裂位置、轴向长度和使用的气体体积在统计学上有差异(p = 0.04,p p = 分别为0.02)。在单次手术成功的组中,手术前后的视力有显著差异(Friedmanχ2 = 40.051,p p > 0.05),术后未观察到青光眼。结论:由于它是一种微创且成本效益高的方法,可以提供快速的视觉康复,因此可以作为适合PR的年轻人的一线治疗。
{"title":"Efficacy of pneumatic retinopexy in young adults with rhegmatogenous retinal detachment.","authors":"Zeynep İpekli,&nbsp;Seren Pehlivanoğlu,&nbsp;Özgür Artunay","doi":"10.1177/25158414231208279","DOIUrl":"https://doi.org/10.1177/25158414231208279","url":null,"abstract":"<p><strong>Background: </strong>In young adults with rhegmatogenous retinal detachment, pneumatic retinopexy can be a cost-effective and minimally invasive highly effective method in suitable cases.</p><p><strong>Objectives: </strong>To evaluate the role of pneumatic retinopexy in the treatment of young adults with rhegmatogenous retinal detachment (RRD) and the factors that may affect the success of pneumatic retinopexy.</p><p><strong>Design: </strong>Retrospective study.</p><p><strong>Methods: </strong>The study included 67 eyes of 67 patients aged between 21 and 40 who underwent pneumatic retinopexy (PR) between January 2015 and June 2021 for primary RRD. We retrospectively analyzed the prognostic factors that may affect the success of PR, such as preoperative age, best corrected visual acuity, tear site, lens condition, and axial length.</p><p><strong>Results: </strong>PR was successful in 61.2% of the patients, whereas 38.8% required secondary surgery. Between the group that had a single surgery (Group 1) and the group that required secondary surgery (Group 2) the tear location, axial length, and volumes of gases used were statistically different (<i>p</i> = 0.04, <i>p</i> < 0.001, and <i>p</i> = 0.02, respectively). There was a significant difference in visual acuity before and after surgery in the group that was successful with a single surgery (Friedman χ<sup>2</sup> = 40.051, <i>p</i> < 0.001). There was no significant difference between the two groups in terms of intraocular pressure (<i>p</i> > 0.05), and glaucoma was not observed in the postoperative period.</p><p><strong>Conclusion: </strong>Since it is a minimally invasive and cost-effective method that provides rapid visual rehabilitation, it can be considered as first-line therapy in young adults who are suitable for PR.</p>","PeriodicalId":23054,"journal":{"name":"Therapeutic Advances in Ophthalmology","volume":"15 ","pages":"25158414231208279"},"PeriodicalIF":2.5,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Therapeutic Advances in Ophthalmology
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