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[Isoflurane anesthesia in rabbits in a closed anesthetic system]. [封闭麻醉系统中异氟醚对家兔的麻醉]。
Pub Date : 1996-12-01
J Henke, M Koch, T Brill, B Bolkart, M Janczewski, W Erhardt

Using the Stephens anaesthetic apparatus-which is a closed system with an in-circuit, nonprecision vaporizer-and isoflurane as anaesthetic gas, 18 rabbits were anaesthetized and showed sufficient hypnosis, analgesia, and muscle relaxation during bone surgery. Induction of anaesthesia was achieved with intravenous propofol and all rabbits were intubated afterwards. During the following isoflurane inhalation anaesthesia the mean arterial blood pressure decreased considerably (compared to control measures before induction), the heart rate remained the same or showed a slight increase, and the respiratory rate decreased. The arterial pO2 decreased corresponding to the respiratory depression after propofol induction and increased again during spontaneous ventilation with 100% oxygen. The changes in arterial pCO2 and pH were representative for a rise in the CO2-stimulation threshold. A moderate metabolic acidosis could be seen due to preanaesthetic excitement of the animals. Recovery time was short (between one and 11 minutes) and no signs of excitation could be detected. The consumed volume of isoflurane was 0.80 ml/kg BW/h.

使用Stephens麻醉装置(一种带非精密汽化器的封闭系统)和异氟醚作为麻醉气体,对18只家兔进行麻醉,在骨手术过程中表现出充分的催眠、镇痛和肌肉松弛。用静脉异丙酚诱导麻醉,随后插管麻醉。在随后的异氟醚吸入麻醉中,平均动脉血压显著下降(与诱导前的对照措施相比),心率保持不变或略有增加,呼吸频率下降。在异丙酚诱导后,动脉pO2随呼吸抑制而降低,在100%供氧自发通气时又升高。动脉pCO2和pH值的变化代表了co2刺激阈值的升高。由于麻醉前动物兴奋,可见中度代谢性酸中毒。恢复时间短(1 ~ 11分钟),无兴奋迹象。异氟烷消耗体积为0.80 ml/kg BW/h。
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引用次数: 0
[Chylothorax in a calf]. [小牛乳糜胸]。
Pub Date : 1996-12-01
N Pusterla, J B Pusterla, B Thür, P Rüsch

A case of chylothorax caused by fracture of thoracal vertebrae in a two-day-old Swiss Braunvieh male calf ist described. The clinical symptoms were those of a unilateral, progressive pleural effusion. This was confirmed by radiological and ultrasonographic examinations. Thoracocentesis was performed under ultrasonographic assistance. The liquid obtained from the pleural cavity was turbid and contained chylomicrons, lymphocytes and neutrophilic granulocytes as well as a high concentration of triglycerides. These qualities go together with chylus. Immunohistological examination for BVD virus turned out to be positive. An intrauterine disturbance of osteogenesis due to BVD virus must be considered a possible cause for fracture of vertebrae during delivery.

一例乳糜胸引起的骨折胸椎骨在一个两天大的瑞士布劳恩维耶雄性小牛的病例。临床表现为单侧进行性胸腔积液。放射学和超声检查证实了这一点。在超声辅助下进行胸穿刺。胸膜腔内的液体浑浊,含有乳糜微粒、淋巴细胞和中性粒细胞以及高浓度的甘油三酯。这些品质与乳糜一起存在。BVD病毒免疫组织学检查呈阳性。由于BVD病毒引起的宫内成骨障碍必须被认为是分娩期间椎骨骨折的可能原因。
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引用次数: 0
[Age-dependence of laboratory values in dogs and cats. III. Bilirubin, creatinine and proteins in serum]. 狗和猫实验值的年龄依赖性。3胆红素、肌酐和血清蛋白[j]。
Pub Date : 1996-12-01
W Kraft, K Hartmann, R Dereser

Serum creatinine and protein are age dependent in the dog as well as in the cat. The differences require consideration of special reference values in young animals. In contrast, the mean value of serum bilirubin shows only a slight, but significant dependency on age in dogs, which is not of diagnostic importance.

血清肌酐和蛋白在狗和猫是年龄依赖。这种差异需要考虑幼龄动物的特殊参考值。相比之下,血清胆红素的平均值对狗的年龄只有轻微但显著的依赖性,这对诊断不具有重要意义。
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引用次数: 0
[Science needs experimental animals]. [科学需要实验动物]。
Pub Date : 1996-12-01
I Kunstyr

Data on the number of animals used in experiments are compared with data on meat consumption. The usefulness of laboratory animals for past achievements in biological sciences is presented. The negative effect of the rather disapproving attitude of the general public and the restrictive Animal Protection Law on Germany as a place of science is demonstrated in the general decrease of the number of registrated scientific projects. Some psychological reasons for the widespread disapproval of animal experiments are listed. The arguments of the opponents and supporters of animal experiments are confronted. Finally, the limits of so-called alternative methods are briefly mentioned and some proposals to ameliorate the keeping conditions of laboratory animals are enumerated.

用于实验的动物数量数据与肉类消费数据进行了比较。介绍了实验动物对过去生物科学成就的有用性。公众相当不赞成的态度和限制性的动物保护法对德国作为科学之地的负面影响体现在科学项目注册数量的普遍减少上。列举了普遍反对动物实验的一些心理原因。动物实验的反对者和支持者的争论被直面了。最后简要介绍了各种替代方法的局限性,并列举了改善实验动物饲养条件的一些建议。
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引用次数: 0
[Dorsal recumbency in dogs--a circulatory risk during surgical treatment?]. [狗的背部卧位——手术治疗期间的循环风险?]。
Pub Date : 1996-12-01
K Gärtner, A Bornscheuer, I Kunstyr, J Maess, E Neumann, K Otto

In this study, changes in hemodynamic, blood gas, and metabolic variables recorded during right lateral and dorsal recumbency in beagles anaesthetised with thiopental are presented. Other than reported in human beings, dorsal recumbency in these dogs resulted in an increase (33%) in heart rate, decrease (30%) in systolic, diastolic, and mean systemic arterial pressure, a decrease (17%) in systemic vascular resistance, and a decrease in both right (31%) and left (39%) ventricular work in comparison with lateral recumbency. Furthermore, mixed-venous PO2, oxygen saturation and respiratory quotient were lower in dorsal than in lateral recumbency while O2 consumption and lipolysis were increased in the former. The changes presented may have been caused by beta-adrenergic stimulation in dorsal recumbency. It needs to be studied if capillary perfusion can be maintained adequately during surgery in dorsal recumbency or if this predisposes to cardiovascular shock.

在这项研究中,记录了用硫喷妥钠麻醉的小猎犬右侧侧卧和背卧时血液动力学、血气和代谢变量的变化。与人类不同,与侧卧相比,这些狗的背侧卧导致心率增加(33%),收缩压、舒张压和平均全身动脉压降低(30%),全身血管阻力降低(17%),右心室功和左心室功降低(31%)。此外,混合静脉PO2、氧饱和度和呼吸商在仰卧时低于侧卧,而在仰卧时氧气消耗和脂肪分解增加。所呈现的变化可能是由于背部平卧时的肾上腺素能刺激引起的。需要研究的是,在手术过程中,是否可以充分保持毛细血管灌注,或者这是否容易导致心血管休克。
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引用次数: 0
[Anesthesia in domestic animals (small mammals, psittacines and reptiles)]. [家畜(小型哺乳动物、鹦鹉和爬行动物)的麻醉]。
Pub Date : 1996-12-01
A Kuntze

The presentation of small animals and exotic pets (birds, reptiles) in veterinary practice is increasing. Physiological and ethological variations demand specific precautions in restraining/ anesthetizing these patients. In Psittacines hypoglycemia, hypoxia and hypothermia are typical side-effects. Long-acting recovery control in birds and reptiles is necessary.

在兽医实践中,小动物和外来宠物(鸟类、爬行动物)的出现越来越多。生理和行为学的变化要求在对这些患者进行抑制/麻醉时采取特定的预防措施。在鹦鹉碱中,低血糖、缺氧和体温过低是典型的副作用。对鸟类和爬行动物的长效恢复控制是必要的。
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引用次数: 0
[Congenital immune deficiency diseases]. [先天性免疫缺陷疾病]。
Pub Date : 1996-12-01
W Kraft
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引用次数: 0
[Stone age deerfly (Lipoptena cervi) found with a mummy in a glacier]. [石器时代的鹿蝇(鹿蝇)与冰川中的木乃伊一起被发现]。
Pub Date : 1996-12-01
R Gothe, H Schöl

In hair samples from the accompanying equipment of a human mummy preserved in glacial ice in South Tyrol for more than 5000 years, numerous remains of insects were found. These fragments corresponded in form, size and structural organization to the features of the deer ked, Lipoptena cervi. Considering the biology and ecology of L. cervi with regard to the finding place of the mummy at an altitude of 3210 m above sea level in a glacier it is concluded that the deer keds invaded the equipment before and not after the death of the Stone Age man.

在南蒂罗尔的冰川中保存了5000多年的一具木乃伊的头发样本中,发现了许多昆虫的遗骸。这些碎片在形态、大小和结构组织上都符合鹿鹿的特征。考虑到在海拔3210米的冰川中发现的鹿颈鹿的生物学和生态学,可以得出结论,鹿颈鹿是在石器时代的人死亡之前而不是之后入侵设备的。
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引用次数: 0
[Maintenance of the cranial cruciate ligament rupture in the dog using an intra-articular ("over-the-top") and an extra-articular ("fascia-doubling") method]. [使用关节内(“过顶”)和关节外(“筋膜加倍”)方法维持狗的颅十字韧带破裂]。
Pub Date : 1996-12-01
C Timmermann, A Meyer-Lindenberg, I Nolte

The present study compares the results of an intraarticular ("over-the-top") and an extraarticular (fascia lata imbrication) surgical method to treat the rupture of the cranial cruciate ligament in dogs. In a period of 18 months, 132 stifle joints of 125 dogs with a partial or complete rupture of the cranial cruciate ligament were examined according to a systematic protocol at the Clinic for Small Animals of the Hannover School of Veterinary Medicine, Hannover, Germany. Surgery was performed with either one or the other of the two surgical techniques. In all cases a " cleaning up " was carried out. If the medial meniscus was damaged, it was resected and the lesion was investigated. The imbrication technique of the lateral aspect of the fascia lata was easier and faster to perform. Using the "over-the-top" method, there were difficulties to guide the fascial strip through the intercondylar notch. After six months 88 patients were re-examined clinically and radiologically according to the same protocol as mentioned above. In the present study it was demonstrated that patients treated with the extraarticular method showed a higher rate (76.5%) of normal limb function after six months and walked earlier without lameness compared with dogs operated with the "over-the-top" technique (41.5%). The same results were valid for patients of giant breeds. Patients operated with the imbrication technique showed more arthrosis of the patellar tip. After six months stability, evaluated with the cranial drawer test and the tibia compression test was satisfying with both techniques.

本研究比较了关节内(“过顶”)和关节外(阔筋膜叠瓦术)手术方法治疗犬颅交叉韧带破裂的结果。在18个月的时间里,根据德国汉诺威兽医学院小动物诊所的系统方案,对125只颅十字韧带部分或完全破裂的狗的132个膝关节进行了检查。手术采用两种手术技术中的一种或另一种进行。在所有情况下都进行了“清理”。如果内侧半月板受损,则将其切除并检查病变。阔筋膜外侧面层压技术操作简单、快捷。使用“过顶”方法,很难引导筋膜带穿过髁间切迹。6个月后,88例患者根据上述相同的方案重新进行临床和放射学检查。在本研究中,与使用“过度”技术(41.5%)的狗相比,使用关节外方法治疗的狗在六个月后显示出更高的肢体功能正常率(76.5%),并且更早地行走而没有跛行。同样的结果也适用于大型品种的患者。采用叠瓦技术的患者表现出更多的髌骨尖端关节。6个月后,用颅骨抽屉试验和胫骨压缩试验评估稳定性,两种技术均令人满意。
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引用次数: 0
[The determination of von Willebrand factor activity in the plasma of dogs. 1. Experimental evaluation and methods]. 犬血浆中血管性血友病因子活性的测定。1. 实验评价与方法]。
Pub Date : 1996-12-01
K Jurina, F Gropp, G Oechtering

Using a new aggregometer, the plasma activity of von Willebrand factor (vWF) in dogs was measured. The method is described. It has the advantage of being more precisely for the diagnosis of von Willebrand's disease than the determination of von Willebrand antigen (vWF: Ag) by using an ELISA. With the method described reproducible and reliable result can be obtained.

采用一种新型聚集仪,测定了犬血浆血管性血友病因子(vWF)的活性。介绍了该方法。与ELISA法测定血管性血友病抗原(vWF: Ag)相比,具有更准确的诊断血管性血友病的优点。用所描述的方法可以得到重复性好、可靠的结果。
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Tierarztliche Praxis
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