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[Killing in wild boar traps - Studies on the point of impact and effects of head shots (caliber .22 lr) in wild boar (Sus scrofa)]. [在野猪陷阱中杀戮-对野猪(Sus scrofa)头部射击(口径。22 lr)的冲击点和效果的研究]。
IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2024-12-01 Epub Date: 2024-12-05 DOI: 10.1055/a-2465-5744
Katharina M Westhoff, André Fetzer, Johannes Lang, Michael Lierz

Objective: The spread of African swine fever in Germany has brought wild boar trapping back into focus as a method for animal disease control. While data on free-bullet slaughter in domestic mammals is available, data on the gun shot and caliber selection for use in wild boar trapping is largely lacking.

Material and methods: The heads of 138 wild boars captured in 10 corral-style traps and shot with a bullet (caliber .22 lr) were analyzed with respect to following data: number of bullet entry holes, bullet entry location, as well as tissue damage to the brain and bleeding by the use of frozen sections of the heads.

Results: With the exception of one animal, all wild boars were killed by head shot with the caliber .22 lr. In 76% (105/138) of the wild boars, only one bullet hole was identified in the head, and in 96% (126/131) of the animals, damage of varying severity was observed in the end brain. In the animals with a frontal bullet hole, in which damage was detected in the cerebrum and brain stem in the frozen sections (n=77), the location was, on average, 2.2 cm above the eye line and 0.35 cm to the right of the median.

Conclusion: The .22 lr caliber appears to be sufficient for culling wild boar with head shots in corral-style wild boar traps. The choice of the smallest possible caliber is of great importance for reasons of animal welfare and safety for the personnel operating the cull.

目的:非洲猪瘟在德国的传播使野猪诱捕作为动物疾病控制的一种方法重新受到关注。虽然关于家养哺乳动物的自由子弹屠宰的数据是可用的,但用于捕获野猪的枪的射击和口径选择的数据在很大程度上是缺乏的。材料与方法:采用10个畜栏式陷阱捕获的138头野猪,用口径0.22 lr的子弹射击,对其头部的射孔数、射孔位置、头部冷冻切片对脑组织的损伤及出血情况进行分析。结果:除1只野猪外,其余野猪均被口径为。22 lr的子弹爆头致死。在76%(105/138)的野猪中,只在头部发现了一个弹孔,96%(126/131)的野猪在大脑末端观察到不同程度的损伤。在冰冻切片中发现大脑和脑干损伤的额叶弹孔动物(n=77),其位置平均在眼线以上2.2 cm,中位数右侧0.35 cm。结论:在畜栏式野猪陷阱中,。22 lr口径似乎足以淘汰头部射击的野猪。为了动物福利和扑杀人员的安全,选择尽可能小的口径是非常重要的。
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引用次数: 0
[Equine granulocytic anaplasmosis (EGA): Case description and overview of the epidemiological situation with focus on Germany]. [马粒细胞无形体病(EGA):病例描述和流行病学概况,重点是德国]。
IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI: 10.1055/a-2418-6540
Carla Wiebke Axt, Andrea Springer, Arno Besse, Torsten J Naucke, Elisabeth Müller, Christina Strube, Ingo Schäfer

Equine granulocytic anaplasmosis (EGA) is a tick-borne disease caused by Anaplasma (A.) phagocytophilum. In Central, Northern, Western, and Eastern Europe, ticks of the Ixodes (I.) ricinus/I. persulcatus complex, in Germany mainly I. ricinus, are considered as vectors. Ixodes ricinus ticks show peaks of activity during the spring and summer months, particularly April to July. Changing climatic conditions, however, have meanwhile led to a year-round risk of tick exposure and thus infections with A. phagocytophilum. The presented case report underlines the seasonal peak phase of the infection risk in that the presentation of the horse to the veterinarian occurred in June. Additionally, clinical signs - including fever - are mostly unspecific and thrombocytopenia represents the most significant hematological abnormality. Direct and indirect detection methods are available for the diagnosis of an infection or contact with the pathogen. A positive PCR confirms an acute infection, as in the presented case, while positive antibody levels indicate contact with the pathogen in the (recent) past. Additionally, inclusion bodies, so called morulae, may be detected rapidly and inexpensively in smears derived from the peripheral blood and are predominantly found in neutrophilic granulocytes, less frequently in eosinophilic granulocytes. However, microscopy has a lower sensitivity compared to PCR-testing. In the presented case, morulae could not be detected in EDTA blood despite positive PCR. Antibiotics with intracellular activity, such as oxytetracycline and/or doxycycline are the treatment of choice and, as in the described case, often result in rapid clinical improvement in horses suffering from EGA. The elimination of the pathogen should be confirmed by PCR-testing 5-8 days after the completion of the antibiotic therapy. Whether and how long antibodies against A. phagocytophilum could possibly be protective against reinfection remains unknown. In humans, A. phagocytophilum is classified as an emerging pathogen of increasing clinical importance in the northern hemisphere.

马粒细胞无形体病(EGA)是由嗜吞噬细胞无形体引起的一种蜱传疾病。在中欧、北欧、西欧和东欧,蓖麻伊蚊(Ixodes ricinus/I.)的蜱。在德国,主要是蓖麻螺旋体,被认为是病媒。蓖麻蜱的活动高峰出现在春季和夏季,特别是4月至7月。然而,不断变化的气候条件同时导致了蜱虫全年暴露的风险,从而感染了嗜吞噬细胞单胞杆菌。所提交的病例报告强调了感染风险的季节性高峰阶段,因为马出现在6月。此外,包括发烧在内的临床症状大多不具有特异性,血小板减少症是最显著的血液学异常。直接和间接检测方法可用于诊断感染或与病原体接触。聚合酶链反应阳性证实为急性感染,如本病例所示,而抗体阳性水平表明(最近)过去曾与病原体接触。此外,包涵体,即所谓的桑葚胚,可以在外周血涂片中快速而廉价地检测到,主要见于中性粒细胞,在嗜酸性粒细胞中较少见。然而,与pcr检测相比,显微镜的灵敏度较低。在本病例中,尽管PCR呈阳性,但EDTA血液中无法检测到桑椹叶。具有细胞内活性的抗生素,如土霉素和/或强力霉素是治疗的选择,正如所描述的情况,通常会导致患有EGA的马的临床迅速改善。应在抗生素治疗完成后5-8天通过pcr检测确认病原体的消除。抗嗜吞噬芽胞杆菌的抗体是否和多长时间可能对再感染有保护作用仍不清楚。在人类中,嗜吞噬细胞芽胞杆菌被归类为北半球临床重要性日益增加的新兴病原体。
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引用次数: 0
[Uroperitoneum in neonatal foals - Investigation on incidence, symptoms, laboratory findings and prognosis]. [新生儿马驹尿腹膜-发生率、症状、实验室检查结果和预后的调查]。
IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2024-12-01 Epub Date: 2024-12-05 DOI: 10.1055/a-2450-9437
André Bernick, Axel Wehrend

Objective: Uroperitoneum is a typical disease in newborn foals. It occurs rarely but regularly. The aim of the present study is to present clinical signs, laboratory findings and prognosis of foals with uroperitoneum.

Material and methods: Medical records of 33 foals suffering from uroperitoneum that were treated between 2006 and June 2018 were reviewed retrospectively.

Results: The incidence was 2.3% based of all presented foals during the first 14 days of life in the investigation period. Colts (78.8%) were significant more often affected (p=0,012) than fillies (21.2%). Common clinical signs were disturbed general condition (79.3%), tachypnea (74.1%), tachycardia (71.4%), distended abdomen (79.2%), highly turgid abdomen (60%) respectively tense abdomen (32%) and straining to urinate (46.7%). The mean age at time of diagnosis was 4.3±3.4 days (median: 3 days, range:<1 to 14 days). 26 foals were treated surgically. 16 foals survived (61.5%). Common laboratory findings at the time of diagnosis were hypochloridemia (91.2%), increased creatinine concentration (77.8%), hyperkaliemia (74.2%) and hyponatriemia (71%). 6 foals developed recurrence of the uroperitoneum. Five foals underwent a second laparotomy, 4 of these survived. The mean duration of hospitalization of healthy discharged foals was 11.6±3.7 days (median: 11 days). Follow-up data was obtained through owner contact for discharged 12 foals six months or longer following surgery (6 months to 9 years). 91.7% of these were alive and none of them developed medical issues in the urinary tract as sequela to surgery of the uroperitoneum.

Conclusion and clinical relevance: The short-term prognosis of uroperitoneum is good when it is recognized and treated early and no or only few concomitant diseases are present. Performing repeated postoperative follow-up sonography examinations is recommended in order to recognize a recurrence of the uroperitoneum early-on. The further long-term prognosis is very good.

目的:尿腹膜是新生马驹的一种典型疾病。这种情况很少发生,但很有规律。本研究的目的是提出临床症状,实验室结果和预后的马驹与尿腹膜。材料与方法:回顾性分析了2006年至2018年6月收治的33例尿腹膜病马驹的病历。结果:在调查期间,所有马驹出生后14天的发病率为2.3%。小马(78.8%)比母马(21.2%)更容易受到影响(p=0,012)。常见的临床症状为全身不适(79.3%)、呼吸急促(74.1%)、心动过速(71.4%)、腹胀(79.2%)、高度腹胀(60%)、腹部紧张(32%)和排尿紧张(46.7%)。诊断时的平均年龄为4.3±3.4天(中位:3天,范围:结论及临床意义:早期发现和治疗,无或仅有少数合并疾病时,尿腹膜短期预后良好。为了及早发现尿腹膜的复发,建议进行多次术后随访超声检查。进一步的长期预后非常好。
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引用次数: 0
[Research priorities and quality of scientific literature on dystocia in cows from 1960-2020]. [1960-2020年奶牛分娩的研究重点和科学文献质量]。
IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-24 DOI: 10.1055/a-2410-1505
Lisa Ulrich, Axel Wehrend

As part of a literature review, a systematic search was carried out to determine how the focus of research on dystocia in cattle has changed in the German- and English-spoken literature between the 1960s and 2020 as well as to evaluate the the quality of the scientific literature to date. To this end, 621 references were analyzed. It is evident that the number of publications increased between 2010 and 2020, which emphasizes the importance of the subject. Case series (35.3%) are the most common type of publication. Controlled studies (4.5%) and meta-analyses (0.3%) were found much less frequently. The causes (43.8%) and consequences of dystocia (28.8%) have been investigated most frequently to date, while the frequency has only been analyzed in few studies (7.2%). While treatment methods were mainly evaluated from 1960 to 1979, no chronological focus can be found for the topics "causes of dystocia" and "consequences of dystocia". Publications focusing on the prevention of dystocia are increasingly found from the 1980s onwards.To summarize, it can be stated that publications on the causes of dystocia are currently the most relevant in quantitative terms. For future research projects, the studies should be planned in such a way that they can form the basis for systematic studies, reviews and meta-analyses.

作为文献综述的一部分,我们进行了系统检索,以确定 20 世纪 60 年代至 2020 年间德语和英语文献中有关牛分娩的研究重点发生了哪些变化,并对迄今为止科学文献的质量进行评估。为此,我们分析了 621 篇参考文献。很明显,2010 年至 2020 年间发表的文献数量有所增加,这凸显了这一主题的重要性。病例系列(35.3%)是最常见的出版物类型。对照研究(4.5%)和荟萃分析(0.3%)则少得多。迄今为止,对难产原因(43.8%)和难产后果(28.8%)的研究最为频繁,而对难产频率进行分析的研究则为数不多(7.2%)。对治疗方法的评估主要集中在 1960 年至 1979 年期间,而对 "子宫收缩的原因 "和 "子宫收缩的后果 "这两个主题则没有按时间顺序进行重点研究。总之,从数量上看,有关子宫收缩原因的出版物是目前最相关的。对于未来的研究项目,应在规划研究时将其作为系统研究、综述和荟萃分析的基础。
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引用次数: 0
[Association between perinatal mortality and the management of cows before and at calving in large dairy herds]. [大型奶牛场围产期死亡率与产犊前和产犊时奶牛管理之间的关系]。
IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-24 DOI: 10.1055/a-2410-1310
Steffi Keller, Karsten Donat, Stefanie Söllner-Donat, Axel Wehrend, Anne Klassen

Objective: Stillbirths account for a relevant proportion of total calf mortality on dairy farms. In addition, the stillbirth rate is an important criterion for assessing animal welfare. The aim of this study was to determine the relationship between the stillbirth rate and aspects concerning the management of cows ante partum and during the calving period in larger dairy herds.

Material and methods: In 97 dairy farms with an average herd size of 550 cattle (≥24 months old), data concerning farm management and animal health were collected as part of a farm inspection using a questionnaire. The stillbirth rate of the respective farms was determined based on the farm's own data on the milk yield test and analyzed for possible correlations with farm management using a multivariable factor analysis.

Results: A higher stillbirth rate was found on farms with particularly lean and overconditioned transit cows in the herd. A positive association to the stillbirth rate was also found for farms using a special birth monitoring system for heifers and those with more than 20% assisted calvings. There was no association with herd size.

Conclusions: Regardless of herd size, factors that are related to the stillbirth rate may be determined by analyzing the farm management. The body condition of the cows is a key parameter. The introduction of special birth monitoring for heifers can probably be interpreted as a reaction to increased stillbirths in the herd.

Clinical relevance: Conditioning cows before calving is an important field of action for herd managers in order to avoid stillbirths. The cows should not approach the calving period in an overly lean or over-conditioned state. When in such state, however, it is advisable for these cows to be monitored more closely in order to allow for professional assistance at the pertinent time period. Integration of body condition scoring of cows at dry-off, calving and the end of the high-yielding period, assessment of calving conditions and training of staff involved in obstetrics into veterinary herd management is warranted.

目的:死胎占奶牛场犊牛总死亡率的相关比例。此外,死胎率也是评估动物福利的一个重要标准。本研究旨在确定死胎率与大型奶牛场产前和产犊期奶牛管理方面的关系:在平均牛群规模为 550 头牛(≥24 月龄)的 97 个奶牛场中,使用调查问卷收集有关牧场管理和动物健康的数据,作为牧场检查的一部分。根据牧场自身的产奶量测试数据确定了各牧场的死胎率,并通过多变量因子分析分析了死胎率与牧场管理的可能相关性:结果发现,饲养特别瘦弱和过度调教过境奶牛的牧场死胎率较高。使用特殊母牛分娩监测系统的牧场和辅助产犊率超过 20% 的牧场的死胎率也呈正相关。死胎率与牛群规模无关:无论牛群规模如何,都可以通过分析牧场管理来确定与死胎率相关的因素。奶牛的体况是一个关键参数。对母牛进行特殊的分娩监测可能是对牛群死胎率上升的一种反应:产犊前的奶牛调教是牛群管理者避免死胎的一个重要行动领域。奶牛不应在过度瘦弱或过度调教的状态下进入产犊期。但是,如果处于这种状态,最好对这些奶牛进行更密切的监测,以便在相关时间段提供专业帮助。有必要将干胎期、产犊期和高产期结束时的奶牛体况评分、产犊情况评估以及产科人员培训纳入兽医牛群管理。
{"title":"[Association between perinatal mortality and the management of cows before and at calving in large dairy herds].","authors":"Steffi Keller, Karsten Donat, Stefanie Söllner-Donat, Axel Wehrend, Anne Klassen","doi":"10.1055/a-2410-1310","DOIUrl":"https://doi.org/10.1055/a-2410-1310","url":null,"abstract":"<p><strong>Objective: </strong>Stillbirths account for a relevant proportion of total calf mortality on dairy farms. In addition, the stillbirth rate is an important criterion for assessing animal welfare. The aim of this study was to determine the relationship between the stillbirth rate and aspects concerning the management of cows ante partum and during the calving period in larger dairy herds.</p><p><strong>Material and methods: </strong>In 97 dairy farms with an average herd size of 550 cattle (≥24 months old), data concerning farm management and animal health were collected as part of a farm inspection using a questionnaire. The stillbirth rate of the respective farms was determined based on the farm's own data on the milk yield test and analyzed for possible correlations with farm management using a multivariable factor analysis.</p><p><strong>Results: </strong>A higher stillbirth rate was found on farms with particularly lean and overconditioned transit cows in the herd. A positive association to the stillbirth rate was also found for farms using a special birth monitoring system for heifers and those with more than 20% assisted calvings. There was no association with herd size.</p><p><strong>Conclusions: </strong>Regardless of herd size, factors that are related to the stillbirth rate may be determined by analyzing the farm management. The body condition of the cows is a key parameter. The introduction of special birth monitoring for heifers can probably be interpreted as a reaction to increased stillbirths in the herd.</p><p><strong>Clinical relevance: </strong>Conditioning cows before calving is an important field of action for herd managers in order to avoid stillbirths. The cows should not approach the calving period in an overly lean or over-conditioned state. When in such state, however, it is advisable for these cows to be monitored more closely in order to allow for professional assistance at the pertinent time period. Integration of body condition scoring of cows at dry-off, calving and the end of the high-yielding period, assessment of calving conditions and training of staff involved in obstetrics into veterinary herd management is warranted.</p>","PeriodicalId":23115,"journal":{"name":"Tieraerztliche Praxis Ausgabe Grosstiere Nutztiere","volume":"52 5","pages":"271-280"},"PeriodicalIF":0.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142508477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How reliable is your diagnosis? 您的诊断有多可靠?
IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-24 DOI: 10.1055/a-2395-6662
Achim D Gruber, Axel Wehrend, Thomas Steidl, Katharina Kramer, Sabine Merbach, Wolfgang Baumgärtner, Thomas Buyle, Niclas-Frederic Weisser, Andreas Beineke

The effectiveness and justification of every therapy and other clinical decisions is based on a correct diagnosis. However, many types of test results can contain uncertainties that may lead to clinically incorrect decisions. The same applies to the reliability of expert opinions for legal disputes. Adequate communication of diagnostic and expert uncertainties in the examination report or expert opinion is therefore crucial for avoiding incorrect decisions. The liability of the person providing the service is also affected. However, uncertain or even erroneous findings can have various causes, only some of which are known to the examining or commissioning person. This article provides an overview of 3 different types of susceptibility to errors using the example of pathological biopsy and cytology examinations, which can also be transferred to other veterinary disciplines in a similar way. A solid understanding of the possible sources of error as well as adequate communication and discussion of case-specific, limited probabilities in investigation reports and expert opinions make a significant contribution to avoiding incorrect decisions. However, commonly used terms such as "highly probable", "suspected" or "cannot be ruled out" are sometimes interpreted in unclear or divergent ways, which are explained here with recommendations for uniform use. This is intended to enable the person making the decision, if necessary, to initiate further diagnostic tests or gather further evidence in the context of all other available data in order to reduce the risk of error as far as possible.

每种疗法和其他临床决定的有效性和合理性都建立在正确诊断的基础上。然而,许多类型的检验结果都可能包含不确定性,从而导致临床上的错误决策。在法律纠纷中,专家意见的可靠性也是如此。因此,在检查报告或专家意见中充分说明诊断和专家的不确定性对于避免做出错误的决定至关重要。提供服务者的责任也会受到影响。然而,不确定甚至错误的检查结果可能有多种原因,其中只有部分原因是检查者或委托者所知道的。本文以病理活检和细胞学检查为例,概述了容易出错的三种不同类型,也可以类似的方式应用到其他兽医学科。充分了解可能的错误来源,并在调查报告和专家意见中充分交流和讨论具体病例的有限可能性,对避免做出错误决定大有裨益。然而,"极有可能"、"疑似 "或 "不能排除 "等常用术语有时会有不明确或不同的解释,本文对此进行了解释,并提出了统一使用的建议。这样做的目的是让做出决定的人能够在必要时根据所有其他可用数据启动进一步的诊断检测或收集进一步的证据,以尽可能降低出错的风险。
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引用次数: 0
[An application for mobile devices as a decision support for the treatment and prevention of bovine fasciolosis - A survey among organic dairy farms in Bavaria]. [移动设备应用作为治疗和预防牛筋膜炎的决策支持--巴伐利亚州有机奶牛场调查]。
IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-24 DOI: 10.1055/a-2410-1490
Charlott-Sophie Haubold, Chris van der Meijden, Friedemann Adler, Anna Rieger, Yury Zablotski, Gabriela Knubben-Schweizer

Subject and aim: Based on health applications used in human medicine for the self-management of chronic diseases, the aim of this study was to evaluate a mobile app in veterinary medicine using the example of a decision-making aid for the control and prevention of bovine fasciolosis on dairy cattle farms.

Material and method: The study was carried out on 37 organic dairy cattle farms in Bavaria. The farms were divided into two groups: one group received a mobile app (n=17) as a decision-making aid, while the other group received a printed brochure (n=20) with identical content. At the beginning of the study, all participants were questioned by telephone concerning their farm, among other things. After using the respective tool, the participants were again interviewed by telephone.

Results: At the beginning of the study, the majority of participants were aware of the options for drainage (n=28; 75.7%) and fencing off wet areas (n=36; 97.3%). 37.8% (n=14) stated that they were familiar with a pasture rotation system. After using the respective aid, the majority of participants described the tool as helpful (94.1% app; 80% brochure). Many participants (app group: n=10 (58.8%); brochure group: n=16 (80%)) stated that they wanted to change their approach based on the new knowledge gained, e. g. introducing a pasture rotation system (app group: n=9 (52.9%); brochure group: n=13 (65.0%)).

Conclusion: Both study groups enjoyed working with the tool they used. They viewed the knowledge imparted by the mobile app or brochure as helpful and useful. Most participants expressed a desire to continue using these tools in animal health management on farms in the future.

Clinical relevance: The use of tools such as mobile apps may improve veterinary advice, e. g. in the management of parasitoses in cattle herds.

主题和目的:本研究以人类医学中用于慢性病自我管理的健康应用程序为基础,以奶牛场控制和预防牛筋膜炎的决策辅助工具为例,对兽医学中的移动应用程序进行评估:研究在巴伐利亚州的 37 个有机奶牛场进行。这些牧场被分为两组:一组接受手机应用程序(n=17)作为决策辅助工具,另一组接受内容相同的印刷手册(n=20)。研究开始时,所有参与者都接受了有关其农场等方面的电话询问。使用相关工具后,参与者再次接受电话采访:研究开始时,大多数参与者都了解排水系统(28 人;75.7%)和潮湿区域围栏(36 人;97.3%)。37.8%(n=14)的参与者表示熟悉牧场轮作系统。使用相关辅助工具后,大多数参与者都认为该工具很有用(应用程序 94.1%;宣传册 80%)。许多参与者(应用程序组:n=10 (58.8%);宣传册组:n=16 (80%))表示,他们希望根据获得的新知识改变自己的方法,例如引入牧场轮作系统(应用程序组:n=9 (52.9%);宣传册组:n=13 (65.0%)):结论:两个研究小组都喜欢使用所使用的工具。他们认为移动应用程序或手册传授的知识是有用的。大多数参与者表示希望今后在农场动物健康管理中继续使用这些工具:临床相关性:移动应用程序等工具的使用可改善兽医建议,例如在牛群寄生虫病管理方面。
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引用次数: 0
Reverse zoonotic transmission of human seasonal influenza to a pig herd in Sweden. 瑞典猪群反向人畜共患病传播人类季节性流感。
IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-24 DOI: 10.1055/a-2410-1530
Kaisa Ryytty Sylvén, Magdalena Jacobson, Lukas Schwarz, Siamak Zohari

In January 2023, a Swedish piglet-producing farm with 2800 sows in production (SIP) was diagnosed with IAV (Influenza A virus) and the isolates were shown to cluster with the human seasonal influenza (2022/2023). In December 2022, employees with flu like symptoms tended to the pigs and a few weeks later, respiratory signs appeared in different age groups; sows in farrowing units were anorectic and pyrectic. Lung and nasal swabs were tested positive for IAV and other respiratory infectious agents. Blanket vaccination against H1N1pdm09 of sows and gilts was initiated but discontinued for sows after 2 treatments. Biosecurity measures aiming to reduce the spread of virus were implemented. However, the compliance to follow the protocol was moderate.Combining immunity and strict sanitary measures is crucial to control virus circulation. As the farmer discontinued sow vaccination and just partly increased biosecurity, this may have contributed to ongoing virus circulation and clinical signs in pigs, even 5 months post-diagnosis. Although H1N1pdm09 already had been found in the herd in 2017, there were no clinical signs or diagnostic results indicating continuous circulation of this or other IAV strains afterwards. However, this cannot be entirely excluded. Swine IAVs pose a risk of reintroduction into the human population, highlighting the importance of vaccination of farm workers against seasonal influenza.

2023 年 1 月,瑞典一家拥有 2800 头在产母猪的仔猪生产猪场(SIP)被确诊感染了 IAV(甲型流感病毒),分离到的病毒与人类季节性流感(2022/2023 年)有聚集现象。2022 年 12 月,出现类似流感症状的员工开始照料猪群,几周后,不同年龄段的猪群都出现了呼吸道症状;产仔单元的母猪出现厌食和腹泻。肺部和鼻拭子对 IAV 和其他呼吸道传染病病原体检测呈阳性。开始对母猪和后备母猪进行 H1N1pdm09 疫苗的全面接种,但母猪在接种 2 次后停止接种。实施了旨在减少病毒传播的生物安全措施。将免疫与严格的卫生措施相结合对控制病毒传播至关重要。由于猪场停止了母猪疫苗接种,只是部分加强了生物安全措施,这可能导致病毒持续传播,甚至在确诊后 5 个月猪只仍出现临床症状。虽然 2017 年已在猪群中发现了 H1N1pdm09,但之后并没有临床症状或诊断结果显示该病毒或其他 IAV 株系在猪群中持续传播。不过,也不能完全排除这种可能性。猪 IAV 存在再次传入人类的风险,这凸显了为农场工人接种季节性流感疫苗的重要性。
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引用次数: 0
In vitro capsule or biofilm formation of Streptococcus uberis and bacteriological cure of bovine mastitis. 尤伯杯链球菌体外胶囊或生物膜的形成以及牛乳腺炎的细菌学治疗。
IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-24 DOI: 10.1055/a-2410-1465
Yanchao Zhang, Nicole Wente, Stefanie Leimbach, Doris Klocke, Anne Tellen, Julia Nitz, Franziska Nankemann, Helen Louton, Volker Krömker

Objective: The relationship between the in vitro detected virulence factors biofilm and capsule formation of Streptococcus (S.) uberis isolates of clinical mastitis in dairy cows and the bacteriological cure rate after antibiotic therapy was investigated in order to better understand the importance of these virulence factors for the bacteriological cure rate.

Material and methods: A total of 111 clinical mastitis (CM) cases were collected, in which S. uberis was bacteriologically detected. All mastitis cases were treated in accordance with the approval conditions of the antibiotic udder tubes used. Individual cow information including age, number of lactations, current lactation mastitis and antimicrobial treatment received was recorded. The microtiter plate test was used to detect biofilm formation and Anthony capsule staining was used to detect capsular capacity. Statistical analyses were performed to characterize the correlation between in vitro virulence factors and bacteriological cure (BC) rate.

Results: 30.5% (n=29) of the S. uberis isolates of bacteriologically cured cases and 34.5% (n=10) of the isolates of bacteriologically non-cured mastitis cases were found to have the ability to produce capsules in vitro. 70.7% (n=58) of the S. uberis isolates from bacteriologically cured mastitis cases had the ability to produce biofilm in vitro, whereas 58.6% (n=17) of the isolates of non-cured mastitis cases showed ability in producing biofilm. No correlation was found between the in vitro ability of S. uberis to form capsules and biofilms and the BC rate after antibiotic treatment of bovine mastitis.

Conclusion(s): The present work has shown that the investigated in vitro virulence factors are not associated with the BC after antibiotic therapy. Further studies on the role of S. uberis virulence factors are needed to complete the missing knowledge on the difficulties in curing S. uberis mastitis.

Clinical relevance: This study is of great clinical relevance since it enhances the understanding of the occurrence of BC in S. uberis mastitis cases. The investigated virulence factors are often addressed as possible reasons for therapy failure, although respective scientific studies are missing.

目的研究奶牛临床乳腺炎中分离的尤伯杯链球菌(S. uberis)体外检测到的毒力因子生物膜和胶囊形成与抗生素治疗后细菌学治愈率之间的关系,以更好地了解这些毒力因子对细菌学治愈率的重要性:材料和方法:共收集了 111 例临床乳腺炎(CM)病例,并对这些病例进行了细菌学检测。所有乳腺炎病例均按照所用抗生素乳房管的批准条件进行治疗。记录奶牛的个体信息,包括年龄、泌乳次数、当前泌乳期乳腺炎和接受的抗菌治疗。微孔板试验用于检测生物膜的形成,安东尼胶囊染色法用于检测胶囊能力。对体外毒力因子与细菌治愈率(BC)之间的相关性进行了统计分析:结果:30.5%(n=29)的细菌学治愈病例和 34.5%(n=10)的细菌学未治愈乳腺炎病例分离株具有体外产生胶囊的能力。在细菌学治愈的乳腺炎病例中,70.7%(n=58)的尤贝菌分离物具有体外产生生物膜的能力,而在未治愈的乳腺炎病例中,58.6%(n=17)的分离物具有产生生物膜的能力。在体外形成胶囊和生物膜的能力与牛乳腺炎抗生素治疗后的 BC 率之间没有发现相关性:本研究表明,所调查的体外毒力因子与抗生素治疗后的乳糜泻率无关。需要进一步研究乌贝氏菌毒力因子的作用,以填补在治疗乌贝氏菌乳腺炎的困难方面所缺失的知识:本研究具有重要的临床意义,因为它加深了人们对乌贝氏菌乳腺炎病例中 BC 发生情况的了解。尽管缺乏相应的科学研究,但所调查的毒力因素往往被视为治疗失败的可能原因。
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引用次数: 0
Use of a slow-release GnRH implant in an adult billy goat. 在成年山羊体内使用缓释 GnRH 植入物。
IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2024-08-01 Epub Date: 2024-08-22 DOI: 10.1055/a-2289-5640
Lukas Demattio, Daniela Fietz, Gerhard Schuler, Axel Wehrend

A 9.4 mg deslorelin slow-release implant was inserted into an adult, healthy billy goat to achieve temporary infertility and a reduction in sexual behavior. The implant was inserted in late autumn. No significant change in testis size was observed over the following 6 weeks. The endocrine function of the testis, which was examined by stimulation with human chorionic gonadotropin, was also unchanged after 6 weeks compared to the initial examination. Histological examination revealed a preserved spermatogenesis.In conclusion, the application of a GnRH analogue implant in the adult male goat has no influence on the investigated parameters - and thus probably also on its fertility.

将 9.4 毫克去氯羟肌苷缓释植入一只成年健康山羊体内,以达到暂时性不育和减少性行为的目的。植入物于深秋植入。在随后的 6 周内,未观察到睾丸大小有明显变化。通过人类绒毛膜促性腺激素对睾丸的内分泌功能进行了检测,6 周后的检测结果与最初的检测结果相比也没有变化。总之,在成年公山羊体内植入 GnRH 类似物对所研究的参数没有影响,因此也可能对其生育能力没有影响。
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引用次数: 0
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Tieraerztliche Praxis Ausgabe Grosstiere Nutztiere
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