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Comparison about the treatment of bronchial asthma by Traditional Chinese Medicine from various nationalities in China 中国各民族中药治疗支气管哮喘的比较
Pub Date : 2023-04-26 DOI: 10.1142/s2575900023300035
Yuxue Cao
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引用次数: 0
Blood donation from 2017 to 2021 in China: a cross-sectional study 2017 - 2021年中国献血:一项横断面研究
Pub Date : 2023-04-26 DOI: 10.1142/s2575900023500027
Jing Wang, Xinyao Pan, Jing Zhou, Ling Wang
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引用次数: 0
Efficacy and safety of Chinese herbal medicine for mammary nodules: A systematic review and meta-analysis 中药治疗乳腺结节的疗效和安全性:一项系统综述和荟萃分析
Pub Date : 2022-10-20 DOI: 10.1142/s257590002250001x
Shuo Zhang, Xin Zhang, Zhen-Lin Chen, Pu Zhang, Miao Wang, Hong-yan Wang, Jing-Ming Zhang
Background: Chinese herbal medicine (CHM) is often used in China to treat patients with mammary nodules (MMND), and treating them by CHM can not only achieve good efficacy, but also reduce adverse reactions in clinic. However, the efficacy of CHM in the treatment of MMND has not been systematically assessed right now. Methods: From the establishment of 11 electronic databases to February 1, 2022, a comprehensive literature search was conducted to evaluate the efficacy and safety of CHM in the treatment of MMND. Relevant trials were screened in NoteExpress, and the risks of bias were assessed with Cochrane Collaboration’s tool. Results: This study included 22 randomized controlled trials involving 3839 participants. Meta-analysis revealed that CHM had a significant clinical effect in treating MMND. Compared with chemical drugs, CHM had certain advantages in alleviating the size, range, hardness and pain of the lump, decreasing the TCM syndrome score and reducing the packed cell volume and whole blood viscosity. And it could obviously reduce the occurrence of adverse reactions. In combination with chemical drugs, CHM could significantly improve the level of sex hormone secretion and ultrasound indicators. Ru-pi-xiao was the most commonly used formula for the treatment of MMND, and Bupleuri Radix was the most frequently used single Chinese herb. Conclusion: CHM had certain advantages in treating MMND without obvious adverse reactions. However, due to the poor methodological quality of the included trials, well-designed, long-term follow-up randomized controlled trials will be required in future to provide strong clinical evidence for the CHM treatment of MMND. (PROSPERO No. CRD42020170939.)
背景:中草药(CHM)在我国经常用于治疗乳腺结节(MMND)患者,在临床上应用中草药治疗不仅可以取得良好的疗效,而且可以减少不良反应。然而,CHM治疗MMND的疗效目前尚未得到系统评估。方法:从建立11个电子数据库到2022年2月1日,对CHM治疗MMND的疗效和安全性进行综合文献检索。相关试验在NoteExpress中进行筛选,并使用Cochrane Collaboration的工具评估偏倚风险。结果:本研究包括22项随机对照试验,涉及3839名参与者。荟萃分析显示中药治疗MMND具有显著的临床疗效。与化学药物相比,中药在减轻肿块的大小、范围、硬度和疼痛、降低中医证候积分、降低堆积细胞体积和全血粘度等方面具有一定的优势。并能明显减少不良反应的发生。中药与化学药物联合应用可显著提高性激素分泌水平和超声指标。乳皮消是治疗MMND最常用的方药,柴胡是最常用的单味中药。结论:中药治疗MMND有一定优势,无明显不良反应。然而,由于纳入试验的方法学质量较差,未来将需要精心设计的长期随访随机对照试验,为CHM治疗MMND提供强有力的临床证据。(PROSPERO编号CRD42020170939。)
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引用次数: 0
Long-term effect of ancient Ayurvedic Agnikarma therapy on heel pain associated with calcaneal spur: A case report 古阿育吠陀阿格尼伽玛疗法对跟骨刺相关足跟疼痛的长期影响:1例报告
Pub Date : 2022-03-30 DOI: 10.1142/s2575900022720016
A. Verma, S. Shete, G. Doddoli
We report the therapeutic effect of ancient Ayurvedic Agnikarma therapy on severe heel pain due to calcaneal spur. The patient, female, 34 years of age, presented with localized, severe and intermittent heel pain which increased with physical activities such as walking or running. A lateral X-ray revealed a large, well-defined bony projection at the base of calcaneus in both the heels. Agnikarma is an ancient Indian Ayurvedic surgical treatment for pain associated with ligament, joints and bones. It involves first- or second-degree burn (thermal cauterization) delivered precisely to the site of pain by using a specialized tool namely Shalaka, made up of five metals. Agnikarma provides instant, long-term and sustainable relief from chronic or acute pain by balancing the local vata and kapha doshas without any side effects. In the present case, Agnikarma treatment was administered for three consecutive weeks and the heel pain was rated on the Pain Analog Scale at each follow-up for up to three years. The patient reported a decrease in pain at each follow-up. No concomitant treatment was given for heel pain during the follow-up period. Agnikarma can have incredible benefits in the management of acute or chronic disorders of joints, ligaments and bones. Further, Agnikarma therapy is cost-effective and does not require hospitalization of the patient.
我们报告了古代阿育吠陀Agnikarma疗法对跟骨骨刺引起的严重足跟疼痛的治疗效果。患者为女性,34岁,表现为局部、严重和间歇性足跟疼痛,这种疼痛随着步行或跑步等体育活动而增加。横向X光片显示,在两个脚后跟的跟骨底部有一个大的、轮廓分明的骨投影。Agnikarma是一种古老的印度阿育吠陀外科治疗与韧带、关节和骨骼相关的疼痛。它涉及一级或二级烧伤(热烧灼),通过使用一种由五种金属制成的专用工具Shalaka精确地将其传递到疼痛部位。Agnikarma通过平衡局部vata和kapha doshas,对慢性或急性疼痛提供即时、长期和可持续的缓解,没有任何副作用。在本例中,Agnikarma治疗连续三周,每次随访时足跟疼痛均采用疼痛模拟量表进行评分,持续时间长达三年。患者报告每次随访时疼痛减轻。在随访期间,没有对足跟疼痛进行联合治疗。Agnikarma在治疗关节、韧带和骨骼的急性或慢性疾病方面有着令人难以置信的益处。此外,Agnikarma疗法具有成本效益,不需要患者住院治疗。
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引用次数: 0
Unprecedented reorganization of developmental history of traditional medicine: Part II 传统医学发展史的空前重组(下)
Pub Date : 2022-01-27 DOI: 10.1142/s2575900021100017
Wenxian Liu, Jing-jing Le, Jingcheng Dong
According to the development of the times and the typical characteristics of medical stages, traditional medicine can be divided into six aspects: legendary traditional medicine, instinctive traditional medicine, witchcraft traditional medicine, empirical traditional medicine, theoretical traditional medicine and integrated traditional medicine. With regard to witchcraft medicine, primitive religion almost became an important source of human knowledge all over the world because the ability of early human beings to understand and transform nature was extremely limited. Medicine has experienced a history of symbiosis with religion, and the blending of medicine and witchcraft is an early feature and necessary stage of Chinese and Western traditional medicines. As for empirical medicine, it is a kind of medicine in the stage of “knowing its nature”. Its main feature is that medical knowledge and technology are mainly based on the practical or applicatory experience (the primary stage of cognition), but not on the “knowing its reason” stage. From the perspective of this development stage, it is a medicine between witchcraft medicine and theoretical medicine.
根据时代发展和医学阶段的典型特征,传统医学可分为六个方面:传说传统医学、本能传统医学、巫术传统医学、实证传统医学、理论传统医学和综合传统医学。就巫术医学而言,由于早期人类理解和改造自然的能力极其有限,原始宗教几乎成为全世界人类知识的重要来源。医学经历了与宗教共生的历史,医巫交融是中西传统医学的早期特征和必要阶段。就实证医学而言,它是一种处于“知其性”阶段的医学。其主要特点是医学知识和技术主要基于实践或应用经验(认知的初级阶段),而不是“知其原因”阶段。从这个发展阶段来看,它是一种介于巫术医学和理论医学之间的医学。
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引用次数: 0
Advances in basic research of traditional Chinese medicine herbal formulae in the treatment of non-small cell lung cancer 中药复方治疗癌症的基础研究进展
Pub Date : 2022-01-26 DOI: 10.1142/s2575900021300010
Linwei Lu, Jingcheng Dong, Weiyi Gong
Today, there is an increasing rate of morbidity and mortality in lung cancer worldwide. In China, lung cancer is also the leading cause of cancer-related death in China. The distinctive herbal therapy from traditional Chinese medicine (TCM) has shown good efficacy in treating lung cancer principally by inhibiting tumor growth or improving the anti-tumor immune response according to considerable experimental studies, which also justifies the concept of dispelling pathogenic qi and strengthening healthy qi in TCM.
今天,全世界癌症的发病率和死亡率都在上升。在中国,肺癌癌症也是中国癌症相关死亡的主要原因。根据大量的实验研究,中医独特的草药疗法主要通过抑制肿瘤生长或改善抗肿瘤免疫反应来治疗癌症,显示出良好的疗效,这也证明了中医祛邪益气的理念是正确的。
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引用次数: 1
Inter-observer agreement on the evaluation of automated breast volume scanner for breast masses 观察者间对自动乳腺体积扫描仪对乳腺肿块的评价的一致意见
Pub Date : 2022-01-14 DOI: 10.1142/s2575900021500026
Yingchun Liu, Lin Chen, Jia Zhan, Xuehong Diao, Y. Pang, Yue Chen, Ling Wang
Objective: To explore inter-observer agreement on the evaluation of automated breast volume scanner (ABVS) for breast masses. Methods: A total of 846 breast masses in 630 patients underwent ABVS examinations. The imaging data were independently interpreted by senior and junior radiologists regarding the mass size ([Formula: see text][Formula: see text]cm, [Formula: see text][Formula: see text]cm and total). We assessed inter-observer agreement of BI-RADS lexicons, unique descriptors of ABVS coronal planes. Using BI-RADS 3 or 4a as a cutoff value, the diagnostic performances for 331 masses with pathological results in 253 patients were assessed. Results: The overall agreements were substantial for BI-RADS lexicons ([Formula: see text]–0.779) and the characteristics on the coronal plane of ABVS ([Formula: see text]), except for associated features ([Formula: see text]). However, the overall agreement was moderate for orientation ([Formula: see text]) for the masses [Formula: see text][Formula: see text]cm. The agreements were substantial to be perfect for categories 2, 3, 4, 5 and overall ([Formula: see text]–0.918). However, the agreements were moderate to substantial for categories 4a ([Formula: see text]), 4b ([Formula: see text]), and 4c ([Formula: see text]), except for category 4b of the masses [Formula: see text][Formula: see text]cm ([Formula: see text]). Moreover, for radiologists 1 and 2, there were no significant differences in sensitivity, specificity, accuracy, positive and negative predictive values with BI-RADS 3 or 4a as a cutoff value ([Formula: see text] for all). Conclusion: ABVS is a reliable imaging modality for the assessment of breast masses with good inter-observer agreement.
目的:探讨自动乳腺体积扫描仪(ABVS)对乳腺肿块的评价在观察者之间的一致性。方法:对630例846个乳腺肿块进行ABVS检查。影像学数据由高级和初级放射科医生独立解释肿块大小([公式:见正文][公式:见文本]cm,[公式:参见文本][公式:参见正文]cm和总计)。我们评估了BI-RADS词典(ABVS冠状面的唯一描述符)的观察者间一致性。以BI-RADS 3或4a为临界值,评估253例患者331个有病理结果的肿块的诊断性能。结果:BI-RADS词典([公式:见正文]-0.779)和ABVS冠状面上的特征([公式,见正文])的总体一致性很高,但相关特征([配方:见正文]])除外。然而,总体一致性是适度的方向([公式:见正文])质量[公式:参见正文][公式:见文本]cm。对于第2类、第3类、第4类、第5类和总体而言,协议是实质性的,是完美的([公式:见正文]-0.918)。然而,对于第4a类([公式,见正文])、第4b类([配方,见正文】)和第4c类(【公式,见文本】),协议是中等到实质性的(除了4b类的质量[公式,见图正文][公式,看正文]cm([公式)。此外,对于放射科医生1和2,以BI-RADS 3或4a为截止值([公式:见正文]),在敏感性、特异性、准确性、阳性和阴性预测值方面没有显著差异。结论:ABVS是一种评估乳腺肿块的可靠成像方式,观察者之间具有良好的一致性。
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引用次数: 1
The multidisciplinary management of gastric cancer: Experience from a tertiary comprehensive hospital in Shanghai, China 癌症的多学科治疗:上海某三级综合医院的经验
Pub Date : 2021-10-04 DOI: 10.1142/s2575900021500014
Hui Cai, Mo Zhang, Zhongxing Fu, Ming-ming Nie, K. Yin, Yan Du
Gastric cancer is a heterogeneous disease which requires a multimodal approach of management. The Department of Gastrointestinal Surgery at Changhai Hospital, a tertiary hospital in Shanghai, established the gastric cancer multidisciplinary team (MDT) clinic based on the guidance of MDT culture in the year of 2017. Our MDT discussion followed a weekly consultation model, with the full-board discussion held once a month, and mini-board communication and discussion made once a week. The stages of MDT management are: pre-operative treatment plan and preparation, post-operative treatment plan, and follow-up treatment and evaluation. As of March 2021, a total of 296 patients visited the MDT clinic. Majority of the patients were gastric carcinoma patients (273/296, 92.2%). Here, we shared our gastric cancer MDT experiences and summarized our strengths and proposed directions for improvement.
癌症是一种异质性疾病,需要多模式的管理方法。2017年,上海市三级医院长海医院消化外科在MDT文化的指导下,成立了胃癌症多学科团队(MDT)诊所。我们的MDT讨论遵循每周咨询模式,每月举行一次全体董事会讨论,每周进行一次小型董事会沟通和讨论。MDT管理的阶段包括:术前治疗计划和准备、术后治疗计划以及后续治疗和评估。截至2021年3月,共有296名患者访问了MDT诊所。大多数患者是胃癌患者(273/296,92.2%)。在此,我们分享了癌症MDT的经验,总结了我们的优势并提出了改进方向。
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引用次数: 0
The implications of mitochondria in doxorubicin treatment of cancer in the context of traditional and modern medicine 线粒体在传统和现代医学背景下多柔比星治疗癌症中的意义
Pub Date : 2020-12-01 DOI: 10.1142/s2575900020300076
L. D. C. M. Souza, Meng Chen, Y. Ikeno, D. Salvadori, Yidong Bai
Doxorubicin (DOX) is an antibiotic anthracycline extensively used in the treatment of different malignancies, such as breast cancer, lymphomas and leukemias. The cardiotoxicity induced by DOX is one of the most important pathophysiological events that limit its clinical application. Accumulating evidence highlights mitochondria as a central role in this process. Modulation of mitochondrial functions as therapeutic strategy for DOX-induced cardiotoxicity has thus attracted much attention. In particular, emerging studies investigated the potential of natural mitochondria-targeting compounds from Traditional Chinese Medicine (TCM) as adjunct or alternative treatment for DOX-induced toxicity. This review summarizes studies about the mechanisms of DOX-induced cardiotoxicity, evidencing the importance of mitochondria and presenting TCM treatment alternatives for DOX-induced cardiomyopathy.
阿霉素(DOX)是一种抗生素蒽环类药物,广泛用于治疗不同的恶性肿瘤,如乳腺癌、淋巴瘤和白血病。DOX引起的心脏毒性是限制其临床应用的最重要的病理生理事件之一。越来越多的证据表明线粒体在这一过程中起着核心作用。因此,线粒体功能的调节作为DOX诱导的心脏毒性的治疗策略引起了人们的广泛关注。特别是,新兴的研究调查了天然线粒体靶向中药化合物作为DOX诱导毒性的辅助或替代治疗方法的潜力。这篇综述综述了关于DOX诱导的心脏毒性机制的研究,证明了线粒体的重要性,并提出了DOX诱导心肌病的中医治疗方案。
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引用次数: 0
Effect of Uygur medicine maturants on related factors of liver energy metabolism in rats 维药成熟剂对大鼠肝脏能量代谢相关因素的影响
Pub Date : 2020-12-01 DOI: 10.1142/s2575900020500111
Ainiwaer Talifu, Rapkat Samat, Yilifanjinag Kuerban, Mamatali Kader, D. Tursun
Objective: To investigate the effects of five Uygur medicine maturants on the related factors of liver energy metabolism in rats. Methods: After 30 days of preparation and intragastric administration, the weight changes of rats were observed. Enzyme-linked immunosorbent assay (ELISA) was used to detect Na[Formula: see text] K[Formula: see text] ATPase, Ca2[Formula: see text] Mg2[Formula: see text] ATPase and succinate dehydrogenase (SDH) activities; hepatic glycogen (HG) and muscle glycogen (MG) content, plasma triiodothyronine (T3), tetraiodothyronine (T4), and thyrotropin (TSH) content were detected. Results: The Kan (blood) quality regulator reduced the weight of rats, the Sapra regulator increased the weight of rats, the Savda maturant group, and the Balham maturant group increased the Na[Formula: see text] K[Formula: see text] ATPase, Ca2[Formula: see text] Mg2[Formula: see text] ATP, SDH activity, HG, MG, T3, T4, and TSH content of rats significantly, while the other groups had no significant effect on the energy metabolism-related factors. Conclusion: Five kinds of Uygur medicine maturants have effects on the related factors of energy metabolism in the liver of normal rats, and their elevation of serum thyroxine level is related, among which the effects of the Savda maturant group and the Balham maturant group are more significant.
目的:观察5种维药成熟剂对大鼠肝脏能量代谢相关因素的影响。方法:大鼠灌胃30天后,观察其体重变化。酶联免疫吸附试验(ELISA)检测Na[式:见正文]K[式:见正文]ATP酶、Ca2[式:未见正文]Mg2[式:详见正文]ATP酶和琥珀酸脱氢酶(SDH)活性;检测肝糖原(HG)和肌糖原(MG)含量、血浆三碘甲状腺原氨酸(T3)、四碘甲状腺原质酸(T4)和促甲状腺激素(TSH)含量。结果:Kan(血液)质量调节剂显著降低大鼠体重,Sapra调节剂显著增加大鼠体重。Savda成熟剂组和Balham成熟剂组大鼠Na[公式:见正文]K[公式:详见正文]ATP酶、Ca2[公式:参见正文]Mg2[公式:见于正文]ATP、SDH活性、HG、MG、T3、T4和TSH含量显著增加,而其他组对能量代谢相关因素无显著影响。结论:五种维药成熟剂对正常大鼠肝脏能量代谢的相关因素均有影响,其血清甲状腺素水平的升高与之有关,其中以Savda成熟剂组和Balham成熟剂组的影响更为显著。
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引用次数: 0
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Traditional Medicine and Modern Medicine
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