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Central nervous system syndrome associated with Marek’s disease in Hubbard broilers 哈伯德肉鸡与马立克氏病相关的中枢神经系统综合征
IF 0.2 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2023-02-21 DOI: 10.21825/vdt.85856
K. Haems, L. Van Brantegem, J. Van Erum, A. Garmyn
Marek’s disease (MD) has a high economic impact in poultry production worldwide. MD consists of several pathologic syndromes of which the most commonly encountered are lymphoproliferative syndromes such as acute MD. Sporadically, MD leads to central nervous system syndromes characterized by non-neoplastic brain pathology. In this case report, an onset of neurological signs on two different broiler farms, housing ‘slow-growing’ Hubbard JA 757 broilers, is described. On the first farm, clinical signs were observed from 42 days of age onwards and on the second farm, respectively from 42 (stable 1) and 30 days (stable 2) of age onwards. The neurological symptoms consisted of acute central nervous system signs, which started with flaccid neck paralysis. Histopathological examination revealed multifocal perivascular cuffing of CD3 positive mononuclear cells in the brain tissues. These findings pointed towards the development of transient paralysis. qPCR analysis confirmed the diagnosis. In broiler flocks, which only have a limited life span, vaccination is not common practice. In flocks of slow-growing breeds, outbreaks of MD might become more important again. Therefore, vaccination of slow-growing broilers against MD seems recommended.
马立克氏病(MD)在全球家禽生产中具有很高的经济影响。MD由几种病理综合征组成,其中最常见的是淋巴增生性综合征,如急性MD。MD偶尔会导致以非肿瘤性脑病理为特征的中枢神经系统综合征。在本病例报告中,描述了两个不同的肉鸡农场发生的神经症状,饲养“生长缓慢”的哈伯德JA 757肉鸡。在第一个农场,从42日龄开始观察临床症状,在第二个农场,分别从42日龄(稳定1日龄)和30日龄(稳定2日龄)开始观察临床症状。神经系统症状包括急性中枢神经系统体征,开始于颈部弛缓性麻痹。组织病理学检查显示脑组织CD3阳性单核细胞多灶性血管周围弯曲。这些发现指向了短暂性麻痹的发展。qPCR分析证实了诊断。在寿命有限的肉鸡群中,接种疫苗是不常见的做法。在生长缓慢的鸡群中,MD的爆发可能会再次变得更加重要。因此,建议给生长缓慢的肉鸡接种抗MD疫苗。
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引用次数: 0
Vraag & Antwoord 问&答
4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2023-02-21 DOI: 10.21825/vdt.85862
E. Claerebout, S. Rutjens, D. Reckelbus
Anthelminthicumresistentie bij paarden – In welke mate zijn eikels giftig voor paarden
马的驱虫剂抗性——橡子对马有多有毒
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引用次数: 0
Proliferative necrotizing otitis externa in two young cats 两只幼猫的增殖性坏死性外耳炎
IF 0.2 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2023-02-21 DOI: 10.21825/vdt.85859
E. J. Tjalsma, N. Meertens
In this paper, proliferative necrotizing otitis externa is described in two young cats. The lesions were characterized by proliferative, erosive to ulcerative dermatitis with necrosis affecting the medial aspect of the pinna, the entrance of the ear canal and the periaural skin of both ears. The lesions developed rapidly and were covered by adherent crusts. Histopathology of the lesions was characterized by severe epidermal hyperplasia, with parakeratotic hyperkeratosis, scattered apoptotic keratinocytes in the epidermis and superficial hair follicle epithelium, and serocellular crusts. In both cases, regression of the lesions appeared after systemic and topical immunomodulatory therapy.
本文描述了两只幼猫的增殖性坏死性外耳炎。病变特点为增殖性,糜烂性至溃疡性皮炎,坏死影响耳廓内侧,耳道入口和双耳耳周皮肤。病变发展迅速,并被附着的结痂覆盖。病变的组织病理学特征为严重的表皮增生,伴角化不全性角化过度,表皮和毛囊浅表上皮中散在的角化细胞凋亡,以及血清细胞结痂。在这两种情况下,病变在全身和局部免疫调节治疗后出现消退。
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引用次数: 0
Runderpestbestrijding in Ethiopië in 1953 - een ooggetuigenis - 1953年在埃塞俄比亚抗击牛瘟疫——一个目击者
IF 0.2 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2022-12-20 DOI: 10.21825/vdt.85522
F. Vandemaele
Geen meer gevreesde veeziekte bij nomadenvolkeren van de Sahel en Oost-Afrika dan runderpest. Wanneer de kwaal toeslaat, is dit voor de veehouders een catastrofe, misschien niet zo zeer omwille van de financiële gevolgen, maar veeleer door het verlies aan prestige en sociale waardigheid. Bij de bewoners van deze regio’s wordt immers traditioneel het bezit van veekudden, vooral runderen, aanzien als de voornaamste maatstaf voor rijkdom en gezag.
在萨赫勒和东非的游牧民族中,没有什么比牛疫更可怕的牛病了。当疾病来袭时,这对饲养牲畜的农民来说是一场灾难,也许不是因为经济后果,而是因为声望和社会尊严的丧失。这些地区的居民传统上认为拥有牛群,尤其是牛,是衡量财富和权威的主要标准。
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引用次数: 0
Imaging features of chronic recurrent multifocal osteomyelitis (CRMO) involving the vertebral column of a lemur with subsequent paraplegia due to pathological fractures 慢性复发性多灶性骨髓炎(CRMO)累及狐猴脊柱并因病理性骨折导致截瘫的影像学特征
IF 0.2 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2022-12-20 DOI: 10.21825/vdt.85517
M. Toom, J. Saunders, G. Vercauteren, R. Haesendonck, A. Quievy, E. Stock
A seven-year-old, female ring-tailed lemur was referred for progressive non-ambulatory paraplegia. A computed tomographic (CT) scan of the whole body revealed multifocal lytic lesions involving multiple vertebrae and several pathological vertebral fractures. Necropsy and histopathology identified pyogranulomatous osteomyelitis. The imaging and histopathological findings resemble chronic recurrent multifocal osteomyelitis described in human medicine.
一只七岁的雌性环尾狐猴被诊断为进行性非活动截瘫。全身计算机断层扫描(CT)显示多局灶性溶解性病变,涉及多椎骨和多处病理性椎体骨折。尸检和组织病理学鉴定为脓肉芽肿性骨髓炎。影像学和组织病理学结果类似于人类医学中描述的慢性复发性多灶性骨髓炎。
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引用次数: 0
Scedosporium apiospermum isolated from a skin wound in a dog and in vitro activity of eleven antifungal drugs 从狗皮肤伤口分离出的顶精子塞多孢子菌及其11种抗真菌药物的体外活性
IF 0.2 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2022-12-20 DOI: 10.21825/vdt.85518
A. Singh, C. Debnath, R. Biswas, R. Barua, N. Gurung
Scedosporium apiospermum, an emerging opportunistic fungus, is increasingly implicated with serious invasive mycoses in immunocompromised patients. Rare occurrence and difficulty in identification of this species complicate the management of infection in dogs. In the present report, the characterization of a Scedosporium apiospermum isolate obtained from a dog’s skin wound is described. Identification was obtained through macroscopic and microscopic examination of the cultured isolate and by sequencing the internal transcribed spacer (ITS) gene of the rRNA region. Numerous hyaline septate hyphae along with conidia were observed histologically. The isolate exhibited low MIC values for voriconazole, itraconazole and isavuconazole while high MIC/MEC values were recorded for the remaining antifungals. To the best of the authors’ knowledge, this is the first reported case of isolation of S. apiospermum from a skin wound in a dog.
顶精子隐孢子菌是一种新兴的机会性真菌,越来越多地与免疫功能低下患者的严重侵袭性真菌病有关。这种疾病的罕见发生和难以识别使犬类感染的管理复杂化。在本报告中,描述了从狗的皮肤伤口中获得的一种顶胚隐孢子菌分离物的特征。通过对培养的分离物进行宏观和微观检查,并对rRNA区域的内部转录间隔(ITS)基因进行测序,获得鉴定。组织学上观察到大量透明分隔菌丝伴分生孢子。该菌株对伏立康唑、伊曲康唑和异戊康唑的MIC值较低,其余抗真菌药物的MIC/MEC值较高。据作者所知,这是第一例报道的从狗的皮肤伤口分离出尖孢链球菌的病例。
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引用次数: 0
Homemade diets for pets: reasons, risks and rewards 宠物自制饮食:原因、风险和回报
IF 0.2 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2022-12-20 DOI: 10.21825/vdt.85521
M. Menniti, C. Baptista da Silva, M. C. Hottat, M. Hesta
Requests for homemade diets are becoming more common in general practice. It is essential that general practice veterinarians understand the advantages, drawbacks and risks of these diets to facilitate evidence-based discussions in the consult room. In the veterinary literature, it has been shown that many clients are choosing to feed homemade diets without consulting a qualified veterinary nutritionist. This may put their pets at risk of nutrient deficiencies. Calcium, phosphorus and vitamin D deficiencies appear to be common as evidenced by selected case studies. In this article, an overview is given of current homemade diet use in general practice, answers to why clients are interested in using them and how to have better discussions with clients about their use.
一般情况下,自制饮食的要求变得越来越普遍。全科兽医必须了解这些饮食的优点、缺点和风险,以便在咨询室中进行基于证据的讨论。在兽医文献中,已经表明,许多客户在没有咨询合格的兽医营养师的情况下选择用自制的饮食。这可能会使他们的宠物面临营养缺乏的风险。一些选定的案例研究证明,钙、磷和维生素D缺乏似乎很常见。在这篇文章中,概述了目前在一般实践中使用的自制饮食,回答了为什么客户对使用它们感兴趣,以及如何更好地与客户讨论它们的使用。
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引用次数: 0
The gut-brain axis: effect of antibiotics on canine drug-resistant idiopathic epilepsy 肠脑轴:抗生素对犬耐药特发性癫痫的影响
IF 0.2 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2022-12-20 DOI: 10.21825/vdt.85520
L. Ledeganck, F. Verdoodt, M. Hesta, I. Cornelis, L. Van Ham, S. Bhatti
Approximately thirty percent of the dogs with idiopathic epilepsy develop multidrug resistance. Therefore, the search for new non-drug treatment alternatives is important. There is a growing interest in the gut-brain axis and its role in the pathogenesis of epilepsy. The gut microbiota can influence brain function by different neural, endocrine, immune and metabolic pathways, but this process is not yet fully understood. In this study, five client-owned dogs with drug-resistant, idiopathic epilepsy received amoxicillin-clavulanic acid as add-on orally (mean duration 32 days (range 21-64 days)). The mean isolated epileptic seizure frequency of these five dogs was 3.3/ week (range 2.5-6.5) with a mean cluster seizure frequency of 0.9/week (range 0.4-1.5). During the amoxicillin-clavulanic acid treatment, three dogs showed complete seizure freedom, one dog showed an 80% decrease of both isolated epileptic seizure and cluster seizure frequency, and one dog showed an increase in isolated epileptic seizure and cluster seizure frequency of 54% and 38%, respectively. In the two-month follow-up period after cessation of the antibiotic administration, the mean isolated epileptic seizure and cluster seizure frequency increased again to 1.5 seizures/week (range 0.9-2.8) and 0.4 clusters/week (range 0.4-0.6), respectively. The preliminary results in this study highlight the need for future research into the role of the canine gut-brain axis in idiopathic epilepsy.
大约30%患有特发性癫痫的狗会产生多药耐药性。因此,寻找新的非药物治疗方案是很重要的。人们对肠脑轴及其在癫痫发病机制中的作用越来越感兴趣。肠道微生物群可以通过不同的神经、内分泌、免疫和代谢途径影响大脑功能,但这一过程尚未完全了解。在这项研究中,5只患有耐药特发性癫痫的客户拥有的狗口服阿莫西林-克拉维酸(平均持续32天(21-64天))。5只犬的平均分离癫痫发作频率为3.3次/周(范围2.5 ~ 6.5次),平均集群癫痫发作频率为0.9次/周(范围0.4 ~ 1.5次)。在阿莫西林-克拉维酸治疗期间,3只犬的癫痫发作完全自由,1只犬的孤立性癫痫发作次数和丛集性癫痫发作次数均下降80%,1只犬的孤立性癫痫发作次数和丛集性癫痫发作次数分别增加54%和38%。在停用抗生素后2个月的随访期间,平均孤立性癫痫发作和丛集性癫痫发作频率再次增加,分别为1.5次/周(范围0.9-2.8)和0.4次/周(范围0.4-0.6)。本研究的初步结果强调需要进一步研究犬肠脑轴在特发性癫痫中的作用。
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引用次数: 0
Accidentele monensin-intoxicatie bij een hond 狗的意外monenen中毒
IF 0.2 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2022-12-20 DOI: 10.21825/vdt.85519
H. De Bosschere, E. Kindermans
Een vijftien maanden oude, mannelijke, gecastreerde labrador retriever werd aangeboden met uitgesproken apathie, bruinrood verkleurde urine, polyurie en polydipsie. Differentiaaldiagnostisch werd initieel aan leptospirose, intoxicatie en acuut nierfalen gedacht. Uit het bloed- en urineonderzoek kon een zeer erge spierbeschadiging afgeleid worden. De eigenaars hadden de hond zien kauwen op een pensbolus met monensin. Monensin-intoxicatie uit zich onder andere in erge myopathie. Dit is een casusbeschrijving van een accidentele monensin-intoxicatie.
一只15个月大的雄性被阉割的拉布拉多寻回犬表现出明显的冷漠、暗红色的尿液、多尿和多饮。鉴别诊断最初被认为是钩端螺旋体病、中毒和急性肾衰竭。血液和尿液分析显示出非常严重的肌肉损伤。主人们看到这只狗在嚼一种带有monensin的彭布罗斯。monensin中毒表现为严重的肌病。这是一个关于意外monenen中毒的案例描述。
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引用次数: 0
Kleuren van het hoornvlies bij kat en hond: wat betekenen ze? 猫和狗的角膜颜色:它们是什么意思?
IF 0.2 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2022-10-31 DOI: 10.21825/vdt.85300
M. Frejlich, E. Capiau
Het hoornvlies vormt het voorste gedeelte van de buitenste laag van het oog en de doorzichtigheid ervan speelt een vitale rol in het oculaire refractieve systeem. Deze transparantie wordt bereikt door een combinatie van fysiologische en anatomische aanpassingen, waaronder een niet-verhoornd oppervlakte-epitheel, de relatieve acellulariteit, een gebrek aan pigment, lymfevaten en bloedvaten en niet-gemyeliniseerde corneazenuwen. Elk proces dat de epitheliale of stromale architectuur van het hoornvlies wijzigt, leidt tot meer corneapigment en bijdraagt tot de migratie van bloedvaten of predisponeert voor cornea-oedeem, tast deze doorzichtigheid aan en duidt op ziekten van het hoornvlies. Infecties en ontstekingen, evenals traumatische of operatie-geïnduceerde letsels van het hoornvlies zijn veelvoorkomende oorzaken van een dergelijk verlies van transparantie. Er zijn meerdere manieren om hoornvliesaandoeningen te classificeren, en de kleur van de aanwezige letsels zou de dierenarts kunnen helpen bij het bepalen van de onderliggende oorzaak en als leidraad kunnen dienen bij de keuze van de juiste therapie
角膜是眼睛外层的前部,其透明度在眼屈光系统中起着至关重要的作用。这种透明度是通过结合生理和解剖学上的调整来实现的,包括未触及的表面上皮、相对粒细胞浓度、缺乏色素、淋巴管和血管以及非髓鞘角膜神经。任何改变角膜上皮或基质结构的过程都会导致角膜增生,导致血管迁移或容易发生角膜水肿,影响这种透明度,并提示角膜疾病。感染和炎症,以及创伤性或手术性角膜损伤是这种透明度丧失的常见原因。有几种方法可以对角膜疾病进行分类,病变的颜色可以帮助兽医确定潜在的原因,并指导选择正确的治疗方法
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引用次数: 0
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