D. Damnjanovic, M. Zamurović, Aleksandar Vranjanac
Introduction. Neurological complications related to epidural anesthesia, even though rare, must be promptly diagnosed in order to introduce adequate therapy in time to prevent further progression of the disorder as well as neurological consequences. One of the rare complications of regional anesthesia is longitudinal extensive transversal myelitis (LETM) described in this paper. Case report. A 32-year old patient, who gave birth by Caesarean section in due term, developed LETM the very same day. Considering the neuroradiological findings indicating to the long central lesion in the thoracic and lumbar spine responding as expected to applied immunotherapy (immunosuppressive therapy and therapeutic plasma exchange), it was diagnosed of longitudinally extensive transverse myelitis. Even with all the therapy and regression of the lesions, patient could not stand up without support. Later on in the course of the treatment, according to physiatrician`s opinion, physical therapy was ordered, to which patient had responded slowly but well, by gradually regaining the function of the lower extremities. Conclusion. An early distinction between possible LETM etiologies is crucial in providing an accurate prognosis and guiding therapeutic strategy.
{"title":"Longitudinally extensive transverse myelitis after epidural anaesthesia in childbirth","authors":"D. Damnjanovic, M. Zamurović, Aleksandar Vranjanac","doi":"10.2298/vsp220901098d","DOIUrl":"https://doi.org/10.2298/vsp220901098d","url":null,"abstract":"Introduction. Neurological complications related to epidural anesthesia, even though rare, must be promptly diagnosed in order to introduce adequate therapy in time to prevent further progression of the disorder as well as neurological consequences. One of the rare complications of regional anesthesia is longitudinal extensive transversal myelitis (LETM) described in this paper. Case report. A 32-year old patient, who gave birth by Caesarean section in due term, developed LETM the very same day. Considering the neuroradiological findings indicating to the long central lesion in the thoracic and lumbar spine responding as expected to applied immunotherapy (immunosuppressive therapy and therapeutic plasma exchange), it was diagnosed of longitudinally extensive transverse myelitis. Even with all the therapy and regression of the lesions, patient could not stand up without support. Later on in the course of the treatment, according to physiatrician`s opinion, physical therapy was ordered, to which patient had responded slowly but well, by gradually regaining the function of the lower extremities. Conclusion. An early distinction between possible LETM etiologies is crucial in providing an accurate prognosis and guiding therapeutic strategy.","PeriodicalId":23531,"journal":{"name":"Vojnosanitetski pregled","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68339636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background/Aim. Diabetes mellitus is a common metabolic disease-causing high mortality and morbidity worldwide. So, physicians need to identify this condition early to implement prevention strategies. The study aimed to test the concept of a novel periodontal device that can be attached to a glucose monitoring device as an innovative tool to screen for periodontitis and diabetes mellitus simultaneously during a routine dental examination. Therefore, correlation of blood glucose between the conventional finger-prick blood glucose (FPBG) and gingival crevicular blood glucose (GCBG) method, along with estimation of patient's pain perception by visual analogue scale (VAS). Methods. A crosssectional comparative study was conducted among 250 participants whose GCBG and FPBG were estimated. VAS score scale was recorded for each patient immediately after the procedure. Results. The mean GCBG value was 151.19 ? 42.64 mg/dL, while mean FPBG was 150.48 ? 42.95 mg/dL, showing a high Pearson's correlation (r=0.9932; p< 0.00001). Mann-Whitney U for VAS score between both the groups showed a statistically significant difference (p < 0.00001). Conclusion. The GCBG method was well tolerated by patients, and highly correlated with peripheral blood glucose levels. The proposed concept of the novel periodontal device appeared to be a feasible option for examining periodontium and screening diabetes simultaneously in dental clinics.
{"title":"Gingival crevicular glucose estimation and patient’s perception of pain during routine dental examination - a concept based on a novel patented periodontal device","authors":"N. Alqahtani, M. Khader, M. Javali","doi":"10.2298/vsp210323056a","DOIUrl":"https://doi.org/10.2298/vsp210323056a","url":null,"abstract":"Background/Aim. Diabetes mellitus is a common metabolic disease-causing high mortality and morbidity worldwide. So, physicians need to identify this condition early to implement prevention strategies. The study aimed to test the concept of a novel periodontal device that can be attached to a glucose monitoring device as an innovative tool to screen for periodontitis and diabetes mellitus simultaneously during a routine dental examination. Therefore, correlation of blood glucose between the conventional finger-prick blood glucose (FPBG) and gingival crevicular blood glucose (GCBG) method, along with estimation of patient's pain perception by visual analogue scale (VAS). Methods. A crosssectional comparative study was conducted among 250 participants whose GCBG and FPBG were estimated. VAS score scale was recorded for each patient immediately after the procedure. Results. The mean GCBG value was 151.19 ? 42.64 mg/dL, while mean FPBG was 150.48 ? 42.95 mg/dL, showing a high Pearson's correlation (r=0.9932; p< 0.00001). Mann-Whitney U for VAS score between both the groups showed a statistically significant difference (p < 0.00001). Conclusion. The GCBG method was well tolerated by patients, and highly correlated with peripheral blood glucose levels. The proposed concept of the novel periodontal device appeared to be a feasible option for examining periodontium and screening diabetes simultaneously in dental clinics.","PeriodicalId":23531,"journal":{"name":"Vojnosanitetski pregled","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68333975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background/Aim. In implant prosthetics, there is an increasing use of materials which, with their mechanical characteristics, can alleviate the negative consequences of implant stress. The aim of this research was to conduct a comparative analysis of stress distribution and deformation of implant supported telescopic systems and surrounding structures, made of different materials, using the finite element method. Methods. 3D finite element models were prepared using (SolidWorks 2018, Concord, MA, USA). Two models of telescopic crowns with the characteristics of polyetheretherketone (PEEK) polymer and cobaltchrome( Co-Cr) alloy faceted with feldspat ceramics were used. The models are loaded with an axial force of 150 N in the region of the central fossa. The analysis of stress and strain distribution was performed by the finite element method in the Ansis software (ANSYS Workbench 16; Ansys Inc., Pittsburg, PA, USA).Results. Implant-supported telescopic crowns made of PEEK polymer significantly reduce stress in the implant and abutment neck area compared to a conventional cobalt-chrome (Co-Cr) crown veneered ceramic. At the level of bone structure, both models showed a concentration of stress at the level of the cortical bone, while the trabecular bone was significantly less exposed to stress. Under the same conditions, the degree of deformation of the secondary telescopic crown was more pronounced in models with PEEK polymer characteristics. Conclusion. Owing to their mechanical characteristics, PEEK polymers can be the materials of choice in the fabrication of superstructures on implants. Given that this in vitro study is accompanied by limitations, further research is needed to confirm the superior role of PEEK material in implant prosthetics.
{"title":"Comparative analysis of stress and deformation distribution in implant supported telescopic systems made of different materials","authors":"Milan Bojović, J. Todić, M. Blagojevic","doi":"10.2298/vsp210403049b","DOIUrl":"https://doi.org/10.2298/vsp210403049b","url":null,"abstract":"Background/Aim. In implant prosthetics, there is an increasing use of materials which, with their mechanical characteristics, can alleviate the negative consequences of implant stress. The aim of this research was to conduct a comparative analysis of stress distribution and deformation of implant supported telescopic systems and surrounding structures, made of different materials, using the finite element method. Methods. 3D finite element models were prepared using (SolidWorks 2018, Concord, MA, USA). Two models of telescopic crowns with the characteristics of polyetheretherketone (PEEK) polymer and cobaltchrome( Co-Cr) alloy faceted with feldspat ceramics were used. The models are loaded with an axial force of 150 N in the region of the central fossa. The analysis of stress and strain distribution was performed by the finite element method in the Ansis software (ANSYS Workbench 16; Ansys Inc., Pittsburg, PA, USA).Results. Implant-supported telescopic crowns made of PEEK polymer significantly reduce stress in the implant and abutment neck area compared to a conventional cobalt-chrome (Co-Cr) crown veneered ceramic. At the level of bone structure, both models showed a concentration of stress at the level of the cortical bone, while the trabecular bone was significantly less exposed to stress. Under the same conditions, the degree of deformation of the secondary telescopic crown was more pronounced in models with PEEK polymer characteristics. Conclusion. Owing to their mechanical characteristics, PEEK polymers can be the materials of choice in the fabrication of superstructures on implants. Given that this in vitro study is accompanied by limitations, further research is needed to confirm the superior role of PEEK material in implant prosthetics.","PeriodicalId":23531,"journal":{"name":"Vojnosanitetski pregled","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68334583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ivana Stankovic, N. Ilić, T. Ilić, L. Jeličić, M. Sovilj, V. Martić, S. Punišić, M. Stokić
Background/Aim. This study aimed to investigate the effect of sensorimotor rhythm (SMR) (12-15 Hz) neurofeedback (NFB) training on auditory cognition measured by achievement on the QuickSIN test, changes in the amplitudes and latencies of evoked potentials in auditory oddball discrimination task and changes in the spectral power of the sensorimotor rhythm. Methods. Each of 16 healthy participants aged 25-40 years (8 male) had 20 daily sessions of SMR neurofeedback training. Auditory cognitive functions and electrophysiological correlates of cognitive processing were recorded 5 times: before NFB, after 5, 10, and 20 sessions, and one month after the last session. Results. The results showed a statistically significant decrease in N200 and P300 latencies at Fz, Cz, and Pz regions, improvement on the QuickSIN test and increase in EEG SMR rhythm spectral power in Cz region as a result of NFB SMR training. No significant effect of NFB training on the amplitude of N100, N200 and P300 on Fz, Cz and Pz was found. Conclusion.The obtained results suggest that sensorimotor rhythm training (SMR) neurofeedback (NFB) affects auditory perception in terms of shorter latencies of evoked potentials and better performance on QuickSIN test.
{"title":"Sensorimotor rhythm neurofeedback training and auditory perception","authors":"Ivana Stankovic, N. Ilić, T. Ilić, L. Jeličić, M. Sovilj, V. Martić, S. Punišić, M. Stokić","doi":"10.2298/vsp210902033s","DOIUrl":"https://doi.org/10.2298/vsp210902033s","url":null,"abstract":"Background/Aim. This study aimed to investigate the effect of sensorimotor rhythm (SMR) (12-15 Hz) neurofeedback (NFB) training on auditory cognition measured by achievement on the QuickSIN test, changes in the amplitudes and latencies of evoked potentials in auditory oddball discrimination task and changes in the spectral power of the sensorimotor rhythm. Methods. Each of 16 healthy participants aged 25-40 years (8 male) had 20 daily sessions of SMR neurofeedback training. Auditory cognitive functions and electrophysiological correlates of cognitive processing were recorded 5 times: before NFB, after 5, 10, and 20 sessions, and one month after the last session. Results. The results showed a statistically significant decrease in N200 and P300 latencies at Fz, Cz, and Pz regions, improvement on the QuickSIN test and increase in EEG SMR rhythm spectral power in Cz region as a result of NFB SMR training. No significant effect of NFB training on the amplitude of N100, N200 and P300 on Fz, Cz and Pz was found. Conclusion.The obtained results suggest that sensorimotor rhythm training (SMR) neurofeedback (NFB) affects auditory perception in terms of shorter latencies of evoked potentials and better performance on QuickSIN test.","PeriodicalId":23531,"journal":{"name":"Vojnosanitetski pregled","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68336301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Odalović, M. Buzejić, G. Zorić, B. Rovčanin, V. Živaljević, S. Cvetkovic, Damir Husović, I. Paunović
Introduction. Parathyroid cysts are divided into two categories: functional and nonfunctional. Both types of parathyroid cysts, if they are large enough, can represent as mediastinal or neck mass in 1-5 %. Case series. We have analyzed data of the patients operated from 2016 till 2021 due to primary hyperparathyroidism or because of cervical/mediastinal mass. Review of patients demographic data, preoperative fine needle aspiration biopsy, level of parathyroid hormone in serum pre and postoperative, level of serum calcium, clinical presentation of disease was done. Total of 555 patients were operated in this period pathological confirmation of parathyroid gland. Parathyroid cysts were found in seven cases. In five cases cyst was nonfunctional. Four female and three male were operated due to parathyroid cyst. Mean age of operated patients was 49,8 years. In one patient nonfunctional cyst was represented with cervical and upper mediastinal mass with maximal diameter of 10 cm. Conclusion. Although parathyroid cysts represent around 0.5% of all parathyroid pathology it should be considered as preoperative diagnose especially if water like liquid is found with fine needle aspiration biopsy. Experience endocrine surgeon should perform operation with preserving cysts wall to avoid parathyreomatosis, and recurrent laryngeal nerve preserving.
{"title":"Surgical treatment of parathyroid cysts: Case series and review of literature","authors":"B. Odalović, M. Buzejić, G. Zorić, B. Rovčanin, V. Živaljević, S. Cvetkovic, Damir Husović, I. Paunović","doi":"10.2298/vsp211125068o","DOIUrl":"https://doi.org/10.2298/vsp211125068o","url":null,"abstract":"Introduction. Parathyroid cysts are divided into two categories: functional and nonfunctional. Both types of parathyroid cysts, if they are large enough, can represent as mediastinal or neck mass in 1-5 %. Case series. We have analyzed data of the patients operated from 2016 till 2021 due to primary hyperparathyroidism or because of cervical/mediastinal mass. Review of patients demographic data, preoperative fine needle aspiration biopsy, level of parathyroid hormone in serum pre and postoperative, level of serum calcium, clinical presentation of disease was done. Total of 555 patients were operated in this period pathological confirmation of parathyroid gland. Parathyroid cysts were found in seven cases. In five cases cyst was nonfunctional. Four female and three male were operated due to parathyroid cyst. Mean age of operated patients was 49,8 years. In one patient nonfunctional cyst was represented with cervical and upper mediastinal mass with maximal diameter of 10 cm. Conclusion. Although parathyroid cysts represent around 0.5% of all parathyroid pathology it should be considered as preoperative diagnose especially if water like liquid is found with fine needle aspiration biopsy. Experience endocrine surgeon should perform operation with preserving cysts wall to avoid parathyreomatosis, and recurrent laryngeal nerve preserving.","PeriodicalId":23531,"journal":{"name":"Vojnosanitetski pregled","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68337636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical characteristics of gynecological patients treated in MINUSCA level II Military Hospital, Bangui, Central African Republic","authors":"N. Jovanović","doi":"10.2298/vsp2202206j","DOIUrl":"https://doi.org/10.2298/vsp2202206j","url":null,"abstract":"<jats:p>nema</jats:p>","PeriodicalId":23531,"journal":{"name":"Vojnosanitetski pregled","volume":"5 2 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68337832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background/Aim. Congenital heart defect (CHD) is the most common type of birth defect and one of the leading causes of infant mortality. It can be isolated or occurs as a part of many different syndromes. The reported worldwide incidence of isolated CHD is between 70 and 120 per 10,000 live births. In this study, we wanted to estimate the incidence of nonsyndromic CHD in the Republic of Srpska and to compare our findings to the literature. Methods. The fetuses, live-born and stillborn infants with CHD during 2015 and 2016 in the Republic of Srpska were analyzed using data from a cross-sectional study. Results. The total incidence of CHD was 163.95 per 10,000 total births and the incidence of live born with CHD was 136.64 per 10,000. Diagnose was established prenatally in 8.09% of cases. The most common type of defect was ventricular septal defect (45.63%), followed by an atrial septal defect (31.40%), patent ductus arteriosus (7.44%) and pulmonary valve stenosis (5.18%). Significant differences in incidence between regions and between different maternal age groups were found. Conclusion. The incidence of CHD in the Republic of Srpska is higher than in other reports with marked heterogeneity between different regions. This study provides baseline data for future monitoring of the risk factors changes and the implementation of primary preventive measures.
{"title":"Incidence of nonsyndromic congenital heart defects in the Republic of Srpska in the period 2015-2016","authors":"Nina Maric, Jelica Predojević-Samardžić, Dario Djukić","doi":"10.2298/vsp220130102m","DOIUrl":"https://doi.org/10.2298/vsp220130102m","url":null,"abstract":"Background/Aim. Congenital heart defect (CHD) is the most common type of birth defect and one of the leading causes of infant mortality. It can be isolated or occurs as a part of many different syndromes. The reported worldwide incidence of isolated CHD is between 70 and 120 per 10,000 live births. In this study, we wanted to estimate the incidence of nonsyndromic CHD in the Republic of Srpska and to compare our findings to the literature. Methods. The fetuses, live-born and stillborn infants with CHD during 2015 and 2016 in the Republic of Srpska were analyzed using data from a cross-sectional study. Results. The total incidence of CHD was 163.95 per 10,000 total births and the incidence of live born with CHD was 136.64 per 10,000. Diagnose was established prenatally in 8.09% of cases. The most common type of defect was ventricular septal defect (45.63%), followed by an atrial septal defect (31.40%), patent ductus arteriosus (7.44%) and pulmonary valve stenosis (5.18%). Significant differences in incidence between regions and between different maternal age groups were found. Conclusion. The incidence of CHD in the Republic of Srpska is higher than in other reports with marked heterogeneity between different regions. This study provides baseline data for future monitoring of the risk factors changes and the implementation of primary preventive measures.","PeriodicalId":23531,"journal":{"name":"Vojnosanitetski pregled","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68337916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Medjo, D. Vujović, M. Atanasković-Marković, Marija Karlicic, T. Radović, D. Nikolić
Introduction. Empyema thoracis, defined as the accumulation of pus in the pleural space, is rare in neonatal population. There are limited data reported in the medical literature and there are still no treatment guidelines available for this age. Case report. We present a healthy term 12-day-old neonate with sepsis caused by methicillin-resistant Staphylococcus aureus (MRSA) and pneumonia associated with advanced stage empyema. The child was admitted to our hospital with a few-hours history of difficulty breathing and lethargy. At the admission, the child was cyanotic with desaturation, in severe respiratory distress, so it was intubated and started mechanical ventilation. Imaging tests were performed in emergency, therefore chest computed tomography (CT) scan was done without contrast. Suspected congenital pulmonary airway malformation (CPAM) with trapped air collections, significant mediastinal shift on CT scan and deterioration of the patient?s condition indicated urgent surgery. Intraoperatively, the diagnosis of stage 2 empyema was established, and decortication of thickened parietal and visceral pleura was performed. Afterwards the baby showed quick and progressive clinical improvement. Conclusion. The diagnosis and management of empyema in neonates may be a challenging one, especially in the case of unremarkably history, fulminant and rapid progression of the disease and incomplete imaging tests.
{"title":"Open pleural decortication in a 12-day-old neonate with empyema thoracis","authors":"B. Medjo, D. Vujović, M. Atanasković-Marković, Marija Karlicic, T. Radović, D. Nikolić","doi":"10.2298/vsp220205096m","DOIUrl":"https://doi.org/10.2298/vsp220205096m","url":null,"abstract":"Introduction. Empyema thoracis, defined as the accumulation of pus in the pleural space, is rare in neonatal population. There are limited data reported in the medical literature and there are still no treatment guidelines available for this age. Case report. We present a healthy term 12-day-old neonate with sepsis caused by methicillin-resistant Staphylococcus aureus (MRSA) and pneumonia associated with advanced stage empyema. The child was admitted to our hospital with a few-hours history of difficulty breathing and lethargy. At the admission, the child was cyanotic with desaturation, in severe respiratory distress, so it was intubated and started mechanical ventilation. Imaging tests were performed in emergency, therefore chest computed tomography (CT) scan was done without contrast. Suspected congenital pulmonary airway malformation (CPAM) with trapped air collections, significant mediastinal shift on CT scan and deterioration of the patient?s condition indicated urgent surgery. Intraoperatively, the diagnosis of stage 2 empyema was established, and decortication of thickened parietal and visceral pleura was performed. Afterwards the baby showed quick and progressive clinical improvement. Conclusion. The diagnosis and management of empyema in neonates may be a challenging one, especially in the case of unremarkably history, fulminant and rapid progression of the disease and incomplete imaging tests.","PeriodicalId":23531,"journal":{"name":"Vojnosanitetski pregled","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68338076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background/Aim. There are a small body of the literature on the influence of perinatal hypoxia (PH) on language outcome at later age and there are no studies on the influence of PH on the extent and severity of language deficit in children with developmental language disorder (DLD). Therefore, the aim of this study was to examine the differences in lexicalsemantic abilities in DLD children with a presence of PH (DLDhpx) and DLD children without any neurological risk factors (DLDwrf). Methods. The sample consisted of 96 children aged 5 to 8, divided into 3 groups, 25 children in DLDhpx, 30 children in DLDwrf and 41 typically developing (TD) peers. For the purpose of comparing age differences, additional categorical variable was formed with two age groups, preschool and school-age children (5-6 and 7-8 years). Lexical-semantic abilities were investigated by specific tests for assessing the expressive vocabulary size, semantic processing, and lexical productivity in continuous speech. Results. The significant differences were observed between DLDhpx and DLDwrf children on the semantic processing assessment test (p < 0.05), but not on the vocabulary size (p = 0.350) and lexical productivity (p = 0.118) assessment tests. However, a detailed analysis of developmental tendencies between preschool and early school-age children showed that DLDhpx children progress significantly only in a domain of expressive vocabulary skills (p < 0.01), while DLDwrf children progress significantly in a domain of expressive vocabulary and semantic processing skills (p < 0.001). Regarding lexical diversity developmental tendencies, significant progress was not observed in both DLD groups. Conclusion. PH in DLD children can be related to a more severe extent of lexical-semantic deficit in the area of semantic processing abilities. Also, PH can contribute to slower progress in a wider spectrum of lexical-semantic abilities. Some of the possible explanations for the obtained results are the possible comorbidity with a specific cognitive deficit, but also that PH can contribute to significantly slower maturation of the brain and neural networks that underlie language abilities.
{"title":"Perinatal hypoxia as a risk factor of severity of lexicalsemantic deficit in children with developmental language disorder","authors":"Bojana Drljan, Nevena Ječmenica","doi":"10.2298/vsp220308076d","DOIUrl":"https://doi.org/10.2298/vsp220308076d","url":null,"abstract":"Background/Aim. There are a small body of the literature on the influence of perinatal hypoxia (PH) on language outcome at later age and there are no studies on the influence of PH on the extent and severity of language deficit in children with developmental language disorder (DLD). Therefore, the aim of this study was to examine the differences in lexicalsemantic abilities in DLD children with a presence of PH (DLDhpx) and DLD children without any neurological risk factors (DLDwrf). Methods. The sample consisted of 96 children aged 5 to 8, divided into 3 groups, 25 children in DLDhpx, 30 children in DLDwrf and 41 typically developing (TD) peers. For the purpose of comparing age differences, additional categorical variable was formed with two age groups, preschool and school-age children (5-6 and 7-8 years). Lexical-semantic abilities were investigated by specific tests for assessing the expressive vocabulary size, semantic processing, and lexical productivity in continuous speech. Results. The significant differences were observed between DLDhpx and DLDwrf children on the semantic processing assessment test (p < 0.05), but not on the vocabulary size (p = 0.350) and lexical productivity (p = 0.118) assessment tests. However, a detailed analysis of developmental tendencies between preschool and early school-age children showed that DLDhpx children progress significantly only in a domain of expressive vocabulary skills (p < 0.01), while DLDwrf children progress significantly in a domain of expressive vocabulary and semantic processing skills (p < 0.001). Regarding lexical diversity developmental tendencies, significant progress was not observed in both DLD groups. Conclusion. PH in DLD children can be related to a more severe extent of lexical-semantic deficit in the area of semantic processing abilities. Also, PH can contribute to slower progress in a wider spectrum of lexical-semantic abilities. Some of the possible explanations for the obtained results are the possible comorbidity with a specific cognitive deficit, but also that PH can contribute to significantly slower maturation of the brain and neural networks that underlie language abilities.","PeriodicalId":23531,"journal":{"name":"Vojnosanitetski pregled","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68338143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Vujović, Jana Desnica, Sara Mijailovic, Dragan Milovanovic
Background/Aim. Assessment of health-related quality of life is fundamental for a better understanding the disease?s effect on different aspects of patients? daily functioning and treatment modalities efficacy. Primary Sj?gren's Syndrome Quality of Life Questionnaire (PSS-QoL) is the first disease-specific instrument for evaluating health-related quality of life in patients with primary Sj?gren syndrome. The aim of this study was to formally translate the PSS-QoL questionnaire from English to Serbian, assess its psychometric properties, and validate it for use in the Serbian population. Methods. The research was designed as a pilot study and included 30 participants. Internal consistency was determined by calculating Cronbach?s alpha coefficient. The construct validity of the questionnaire was estimated by the correlation of its overall result with the patients? EuroQoL-5D, EULAR SS Patients Reported Index, Oral Health Impact Profile-14, and Emotion Regulation Questionnaire scores. Results. There were 29 (96.7%) female participants and one (3.3%) male participant in the research. The average (? SD) score of PSS-QoL was 44.63 ? 12.901 at baseline and 41.70 ? 12.075 at follow-up. Cronbach?s alpha value of the Serbian version of PSS-QoL was 0.922. The test-retest intraclass correlation coefficient was 0.981 (95% CI: 0.436-0.996). Analysis revealed a statistically significant moderate to strong correlation between PSS-QoL scores and EuroQol-5D (rs = -0.696), EULAR SS Patients Reported Index (rs = 0.883), and Oral Health Impact Profile-14 scores (rs = 0.809). Conclusion. Serbian adaptation of the PSS-QoL instrument can be used to evaluate the health-related quality of life of patients with primary Sj?gren syndrome both in academic research and in clinical practice as a novel outcome measure.
{"title":"Translation, transcultural adaptation, and validation of the Serbian version of the PSS-QoL questionnaire: A pilot research","authors":"S. Vujović, Jana Desnica, Sara Mijailovic, Dragan Milovanovic","doi":"10.2298/vsp220518080v","DOIUrl":"https://doi.org/10.2298/vsp220518080v","url":null,"abstract":"Background/Aim. Assessment of health-related quality of life is fundamental for a better understanding the disease?s effect on different aspects of patients? daily functioning and treatment modalities efficacy. Primary Sj?gren's Syndrome Quality of Life Questionnaire (PSS-QoL) is the first disease-specific instrument for evaluating health-related quality of life in patients with primary Sj?gren syndrome. The aim of this study was to formally translate the PSS-QoL questionnaire from English to Serbian, assess its psychometric properties, and validate it for use in the Serbian population. Methods. The research was designed as a pilot study and included 30 participants. Internal consistency was determined by calculating Cronbach?s alpha coefficient. The construct validity of the questionnaire was estimated by the correlation of its overall result with the patients? EuroQoL-5D, EULAR SS Patients Reported Index, Oral Health Impact Profile-14, and Emotion Regulation Questionnaire scores. Results. There were 29 (96.7%) female participants and one (3.3%) male participant in the research. The average (? SD) score of PSS-QoL was 44.63 ? 12.901 at baseline and 41.70 ? 12.075 at follow-up. Cronbach?s alpha value of the Serbian version of PSS-QoL was 0.922. The test-retest intraclass correlation coefficient was 0.981 (95% CI: 0.436-0.996). Analysis revealed a statistically significant moderate to strong correlation between PSS-QoL scores and EuroQol-5D (rs = -0.696), EULAR SS Patients Reported Index (rs = 0.883), and Oral Health Impact Profile-14 scores (rs = 0.809). Conclusion. Serbian adaptation of the PSS-QoL instrument can be used to evaluate the health-related quality of life of patients with primary Sj?gren syndrome both in academic research and in clinical practice as a novel outcome measure.","PeriodicalId":23531,"journal":{"name":"Vojnosanitetski pregled","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68338838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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