Green betel leaf (Piper betle) is used in the manufacture of wound healing preparations, has a function as an antiseptic and eugenol that can kill bacteria. This study aims to characterize the process of making simplicia and simplicia green betel leaf (Piper betle L.) obtained at Jalan Parit Demang, Gg. Kulang Leather, Parit Tokaya No. 6, South Pontianak District, Pontinanak City, West Kalimantan 78121 which is used as raw material for wound healing drug preparations. Green betel leaf simplicia was characterized biologically including habitat, morphology, physically including organoleptic, microscopic, water content, ash content, and acid insoluble ash content, as well as chemically namely phytochemical screening. This characterization is also carried out in the process of making simplicia picking, wet sorting, packing, washing, dry sorting, making simplicia, packaging, and storage. The yield of simplicia was 23.27%. The results of the characterization of green betel leaf are at an altitude of 200-1000 m above sea stage which has a rainfall of 2250-4750 mm in keeping with year. Heart-fashioned leaves, sleek leaf surface, pointed with a leaf period of 6-17.5 cm and a width of 3.5-10 cm.betle leaves have a distinctive aroma, taste slightly spicy, and greenish brown in color. The water content, ash content, acid insoluble ash content and total phenol in green betel leaf simplicia were 12.8%, 7.04%, 3.13%, phenol content 760 nm, absorbance 0.0520 and obtained levels of 23.3379 ppm. Positive for alkaloids, flavonoids, saponins, triterpenoids, tannins.
{"title":"Karakterisasi Proses Pembuatan Simplisia Daun Sirih Hijau (Piper Betle) Sebagai Sediaan Obat Penyembuhan Luka","authors":"Paskalis Trianus Kiko, Wintari Taurina, Mohamad Andrie","doi":"10.37311/ijpe.v3i1.18808","DOIUrl":"https://doi.org/10.37311/ijpe.v3i1.18808","url":null,"abstract":"Green betel leaf (Piper betle) is used in the manufacture of wound healing preparations, has a function as an antiseptic and eugenol that can kill bacteria. This study aims to characterize the process of making simplicia and simplicia green betel leaf (Piper betle L.) obtained at Jalan Parit Demang, Gg. Kulang Leather, Parit Tokaya No. 6, South Pontianak District, Pontinanak City, West Kalimantan 78121 which is used as raw material for wound healing drug preparations. Green betel leaf simplicia was characterized biologically including habitat, morphology, physically including organoleptic, microscopic, water content, ash content, and acid insoluble ash content, as well as chemically namely phytochemical screening. This characterization is also carried out in the process of making simplicia picking, wet sorting, packing, washing, dry sorting, making simplicia, packaging, and storage. The yield of simplicia was 23.27%. The results of the characterization of green betel leaf are at an altitude of 200-1000 m above sea stage which has a rainfall of 2250-4750 mm in keeping with year. Heart-fashioned leaves, sleek leaf surface, pointed with a leaf period of 6-17.5 cm and a width of 3.5-10 cm.betle leaves have a distinctive aroma, taste slightly spicy, and greenish brown in color. The water content, ash content, acid insoluble ash content and total phenol in green betel leaf simplicia were 12.8%, 7.04%, 3.13%, phenol content 760 nm, absorbance 0.0520 and obtained levels of 23.3379 ppm. Positive for alkaloids, flavonoids, saponins, triterpenoids, tannins.","PeriodicalId":249696,"journal":{"name":"Indonesian Journal of Pharmaceutical Education","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116325348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The strongest cause of premature aging is sunlight (photoaging), especially UV A rays. Anti-aging creams containing antioxidant compounds can be used in the treatment of aging on the skin of the face. Red spinach leaves (Amaranthus tricolor L.) are a natural source of antioxidants that have very strong potential as an anti-aging. Objectives: This study aims to determine the activity of red spinach leaf extract cream as an anti-aging using New Zealand rabbits exposed to UV-A rays. The skin of the rabbit's back is smeared with cream F1, F2, F3, F4, F5 for 30 days. Parameter observation using a skin analyzer is carried out before, after induction, and after cream smearing. Parameters include percent collagen, elasticity, and moisture. The results of the study were analyzed statistically using one way anova. All test creams pass the physical quality test requirements, but the creams that pass the stability test are F1, F2, F4. The primary irritation test F1, F2, F4 is not irritating whereas F3 is very little irritating. Test the ocular irritation of all creams is not irritating. The test results of anti-aging activity show that F2 provides the most effective anti-aging effect because the percent increase in parameters is the greatest.
{"title":"Uji Aktivitas Krim Anti-Aging Ekstrak Etanol Daun Bayam Merah (Amaranthus tricolor L.) pada Kulit Punggung Kelinci New Zealand yang dipapar Sinar UV-A","authors":"Ananda Rezky Putri, Suhartinah Suhartinah, Metasari Kartika","doi":"10.37311/ijpe.v3i1.18809","DOIUrl":"https://doi.org/10.37311/ijpe.v3i1.18809","url":null,"abstract":"The strongest cause of premature aging is sunlight (photoaging), especially UV A rays. Anti-aging creams containing antioxidant compounds can be used in the treatment of aging on the skin of the face. Red spinach leaves (Amaranthus tricolor L.) are a natural source of antioxidants that have very strong potential as an anti-aging. Objectives: This study aims to determine the activity of red spinach leaf extract cream as an anti-aging using New Zealand rabbits exposed to UV-A rays. The skin of the rabbit's back is smeared with cream F1, F2, F3, F4, F5 for 30 days. Parameter observation using a skin analyzer is carried out before, after induction, and after cream smearing. Parameters include percent collagen, elasticity, and moisture. The results of the study were analyzed statistically using one way anova. All test creams pass the physical quality test requirements, but the creams that pass the stability test are F1, F2, F4. The primary irritation test F1, F2, F4 is not irritating whereas F3 is very little irritating. Test the ocular irritation of all creams is not irritating. The test results of anti-aging activity show that F2 provides the most effective anti-aging effect because the percent increase in parameters is the greatest.","PeriodicalId":249696,"journal":{"name":"Indonesian Journal of Pharmaceutical Education","volume":"2020 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131986047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-03DOI: 10.37311/ijpe.v2i3.15863
Ferna Indrayani, Nur Hikma
Emprit ginger (Zingiber officinale var. amarum) is a rhizome plant that is much of the time tracked down in the locale. Tanasitolo, Kab. Wajo. Its utilization is most generally utilized as a cooking zest, defeating joint inflammation, muscle torment, treating colds, treating hacks, as a characteristic cell reinforcement and warming the body. The compound parts contained in emprit ginger (Zingiber officinale var. amarum) are zingiberene, shagaol, sap, and gingerol which are adequate as cancer prevention agents and mitigating or then again reflexology. This study aims to decided how to of ginger emprit (Zingiber officinale var. amarum) as a salve form of a natural balm. This type of research is a direct observation in the laboratory using the distillation method to obtain the essential oil in ginger emprit (Zingiber officinale var. amarum) was then made in the form of a balm with different concentrations of essential oils, namely F1 (0 g), F2 (1.5 g), and F3 (2 g) using accelerated stability testing on the balm preparation, stored for 6 days with 3 cycles (40C and 400C) the observations included organoleptic tests (shape, smell, and colour), homogeneity test, pH test, spreadability test, adhesion test, and specific gravity.. This study indicate that a stable balm preparation that meets the standard requirements based on SNI with accelerated stability testing is formula F3 with a concentration of 2 grams of ginger essential oil. Emprit ginger (Zingiber officinale var. amarum) can be formed in a balm preparation.
生姜(Zingiber officinale var. amarum)是一种根茎植物，大部分时间都在当地找到。Tanasitolo,出租车。Wajo。它的用途通常是作为烹饪的调味料，治疗关节炎症，肌肉疼痛，治疗感冒，治疗黑客，作为一种典型的细胞增强和温暖身体。生姜(Zingiber officinale varm . amarum)中所含的复合成分是姜黄烯、沙芦酚、汁液和姜辣素，足以作为防癌剂和缓解反射作用。本研究旨在确定如何将生姜提取物(Zingiber officinale var. amarum)作为一种天然的软膏形式。这种类型的研究是一个直接观察在实验室使用蒸馏法获得的精油姜emprit(生姜var. amarum)当时在的形式与不同浓度的乳香精油,即F1 (0 g)、(1.5 g), F2和F3 (2 g)在唇膏使用加速稳定性试验准备、存储与3周期6天(40摄氏度和400 c)的观察包括感官测试(形状、味道和颜色),均匀性测试,pH值试验、涂布性试验、附着力试验、比重试验。本研究表明，基于SNI加速稳定性试验，符合标准要求的稳定香脂制剂为配方F3，姜精油浓度为2g。Emprit姜(Zingiber officinale var. amarum)可以在香脂制剂中形成。
{"title":"The Formulation and Stability Test of The Balm Emprit Ginger (Zingiber officinale var. amarum) Essential Oil","authors":"Ferna Indrayani, Nur Hikma","doi":"10.37311/ijpe.v2i3.15863","DOIUrl":"https://doi.org/10.37311/ijpe.v2i3.15863","url":null,"abstract":"Emprit ginger (Zingiber officinale var. amarum) is a rhizome plant that is much of the time tracked down in the locale. Tanasitolo, Kab. Wajo. Its utilization is most generally utilized as a cooking zest, defeating joint inflammation, muscle torment, treating colds, treating hacks, as a characteristic cell reinforcement and warming the body. The compound parts contained in emprit ginger (Zingiber officinale var. amarum) are zingiberene, shagaol, sap, and gingerol which are adequate as cancer prevention agents and mitigating or then again reflexology. This study aims to decided how to of ginger emprit (Zingiber officinale var. amarum) as a salve form of a natural balm. This type of research is a direct observation in the laboratory using the distillation method to obtain the essential oil in ginger emprit (Zingiber officinale var. amarum) was then made in the form of a balm with different concentrations of essential oils, namely F1 (0 g), F2 (1.5 g), and F3 (2 g) using accelerated stability testing on the balm preparation, stored for 6 days with 3 cycles (40C and 400C) the observations included organoleptic tests (shape, smell, and colour), homogeneity test, pH test, spreadability test, adhesion test, and specific gravity.. This study indicate that a stable balm preparation that meets the standard requirements based on SNI with accelerated stability testing is formula F3 with a concentration of 2 grams of ginger essential oil. Emprit ginger (Zingiber officinale var. amarum) can be formed in a balm preparation.","PeriodicalId":249696,"journal":{"name":"Indonesian Journal of Pharmaceutical Education","volume":"53 68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115374390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-29DOI: 10.37311/ijpe.v2i3.12025
Rahmatia Is. Kaluku, Robert Tungadi, Nurain Thomas
Curcumin a hydrophobic polyphenolic compound and water-insoluble that creates low systemic bioavailability inside the body, has broad pharmacological activity, including anti-inflammation. This study aims to formulate, characterize and evaluate the nanoemulsion based on curcumin through an in vitro transdermal patch preparation. This study starts from formulating a curcumin nanoemulsion solution and characterizing the particle size of curcumin through PSA (Particle Size Analyzer). Further, it formulates the transdermal patch preparation with the smallest curcumin particles within three concentrations (HEC 0,625%, 1,25%, and 2,5%) combined with HPMC 2,5% as polymer. Those formulations are evaluated through organoleptic, thickness, weight uniformity, humidity, and folding resistance tests. In the next step, this study examines the penetration through an in vitro by using a franz diffusion cell within 72 hours. The result shows increasing penetration on each formula where the best penetrations occur in the 15th and 24th hours. It also discovers that the formula containing HEC 2,5% (2c) creates the highest cumulative drug penetration (15,83%). Therefore, it deduces that curcumin nanoemulsion in the transdermal patch has good characteristics and is compatible between drug and polymer.
{"title":"Effect of HEC (Hydroxyethyl Cellulose) Polymer on Nanoemulsion-Based Curcumin Transdermal Patch Release","authors":"Rahmatia Is. Kaluku, Robert Tungadi, Nurain Thomas","doi":"10.37311/ijpe.v2i3.12025","DOIUrl":"https://doi.org/10.37311/ijpe.v2i3.12025","url":null,"abstract":"Curcumin a hydrophobic polyphenolic compound and water-insoluble that creates low systemic bioavailability inside the body, has broad pharmacological activity, including anti-inflammation. This study aims to formulate, characterize and evaluate the nanoemulsion based on curcumin through an in vitro transdermal patch preparation. This study starts from formulating a curcumin nanoemulsion solution and characterizing the particle size of curcumin through PSA (Particle Size Analyzer). Further, it formulates the transdermal patch preparation with the smallest curcumin particles within three concentrations (HEC 0,625%, 1,25%, and 2,5%) combined with HPMC 2,5% as polymer. Those formulations are evaluated through organoleptic, thickness, weight uniformity, humidity, and folding resistance tests. In the next step, this study examines the penetration through an in vitro by using a franz diffusion cell within 72 hours. The result shows increasing penetration on each formula where the best penetrations occur in the 15th and 24th hours. It also discovers that the formula containing HEC 2,5% (2c) creates the highest cumulative drug penetration (15,83%). Therefore, it deduces that curcumin nanoemulsion in the transdermal patch has good characteristics and is compatible between drug and polymer.","PeriodicalId":249696,"journal":{"name":"Indonesian Journal of Pharmaceutical Education","volume":"2014 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127540513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-22DOI: 10.37311/ijpe.v2i3.15654
Khairil Pahmi, Muhammad Ricky Ramadhian, Gabena Indrayani Dalimunthe
Pepper elder (Peperomia pellucida) and green chiretta (Andrographis paniculata) are plants that have been used empirically to reduce fever. Fever is a symptom of a disease characterized by a significant increase in body temperature. This study aimed to determine the antipyretic effect of the combination of pepper elder herbal extract (P. pellucida) and green chiretta herbal extract (A. paniculata) (80:20) in the male house mice (Mus musculus). Extraction was conducted through maceration using ethyl acetate solvent. The total of 25 male mice were divided into 5 groups, namely a negative control group (Na-CMC 1%), a positive control group (paracetamol), and a treatment group induced by a combination of pepper elder herbal extracts and green chiretta herbal extract at the dose of (80 + 20), (40 +10), and (20 + 5) mg/kg BW. DPT vaccine 0.2 ml was used intramuscularly as a fever inducer. The observation was carried out at 30, 60, 90, and 120 minutes after treatment. The data obtained were analyzed using one-way ANOVA followed by the LSD test to determine the differences between groups. The results showed that variations in the dose of the combination of pepper elder and green chiretta herbal extracts had an antipyretic effect where the most effective dose was (80 + 20) mg/kg BW due to its stable temperature reduction power and effectiveness that are equivalent to paracetamol. The combination of suruhan herb extract (P. pellucida) and sambiloto herb (A. paniculata) has potential as an antipyretic
{"title":"Antipyretic Activity Test of Combination of Peperomia pellucida Extract and Andrographis paniculata in Mice (Mus musculus)","authors":"Khairil Pahmi, Muhammad Ricky Ramadhian, Gabena Indrayani Dalimunthe","doi":"10.37311/ijpe.v2i3.15654","DOIUrl":"https://doi.org/10.37311/ijpe.v2i3.15654","url":null,"abstract":"Pepper elder (Peperomia pellucida) and green chiretta (Andrographis paniculata) are plants that have been used empirically to reduce fever. Fever is a symptom of a disease characterized by a significant increase in body temperature. This study aimed to determine the antipyretic effect of the combination of pepper elder herbal extract (P. pellucida) and green chiretta herbal extract (A. paniculata) (80:20) in the male house mice (Mus musculus). Extraction was conducted through maceration using ethyl acetate solvent. The total of 25 male mice were divided into 5 groups, namely a negative control group (Na-CMC 1%), a positive control group (paracetamol), and a treatment group induced by a combination of pepper elder herbal extracts and green chiretta herbal extract at the dose of (80 + 20), (40 +10), and (20 + 5) mg/kg BW. DPT vaccine 0.2 ml was used intramuscularly as a fever inducer. The observation was carried out at 30, 60, 90, and 120 minutes after treatment. The data obtained were analyzed using one-way ANOVA followed by the LSD test to determine the differences between groups. The results showed that variations in the dose of the combination of pepper elder and green chiretta herbal extracts had an antipyretic effect where the most effective dose was (80 + 20) mg/kg BW due to its stable temperature reduction power and effectiveness that are equivalent to paracetamol. The combination of suruhan herb extract (P. pellucida) and sambiloto herb (A. paniculata) has potential as an antipyretic","PeriodicalId":249696,"journal":{"name":"Indonesian Journal of Pharmaceutical Education","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126191882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-20DOI: 10.37311/ijpe.v2i3.15658
Ari Dwidayati, M. Asri, A. Putri, Nurfitria Junita
Srikaya leaf (Annona squamosa L.) is a plant that contains several active compounds including flavonoids, saponins, alkaloids and tannins which have antibacterial properties. Transparent antiseptic extract of srikaya leaf (Annona squamosa L.) has antibacterial activity against Staphylococcus aureus. This research method is an experimental study with physical and chemical evaluation of the preparation as well as testing of antibacterial activity using the paper disc technique diffusion method at concentrations of 1%, 2%, 3%, negative control and positive control. The results of the study at concentrations of 1%, 2% and 3% met the physical and chemical requirements as well as the antibacterial activity test with a concentration of 1% inhibition zone 15.6 mm (Strong), 2% inhibition zone 19.6 mm (Strong) and 3% zone of inhibition 21.2 mm (Very strong). It was concluded that for a concentration of 3% with an inhibition zone diameter of 21.2 mm (Very strong) the most effective.
{"title":"Formulation and Antibacterial Potential Activity Test of Antiseptic Transparent Soap Preparations Srikaya Leaf (Annona squamosa L.)","authors":"Ari Dwidayati, M. Asri, A. Putri, Nurfitria Junita","doi":"10.37311/ijpe.v2i3.15658","DOIUrl":"https://doi.org/10.37311/ijpe.v2i3.15658","url":null,"abstract":"Srikaya leaf (Annona squamosa L.) is a plant that contains several active compounds including flavonoids, saponins, alkaloids and tannins which have antibacterial properties. Transparent antiseptic extract of srikaya leaf (Annona squamosa L.) has antibacterial activity against Staphylococcus aureus. This research method is an experimental study with physical and chemical evaluation of the preparation as well as testing of antibacterial activity using the paper disc technique diffusion method at concentrations of 1%, 2%, 3%, negative control and positive control. The results of the study at concentrations of 1%, 2% and 3% met the physical and chemical requirements as well as the antibacterial activity test with a concentration of 1% inhibition zone 15.6 mm (Strong), 2% inhibition zone 19.6 mm (Strong) and 3% zone of inhibition 21.2 mm (Very strong). It was concluded that for a concentration of 3% with an inhibition zone diameter of 21.2 mm (Very strong) the most effective.","PeriodicalId":249696,"journal":{"name":"Indonesian Journal of Pharmaceutical Education","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126349037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-17DOI: 10.37311/ijpe.v2i3.15455
Erinda Risma Puspita Cahya, Dewi Ekowati, Dwi Ningsih
Emulgel is an emulsion of both O/W and W/O which is made into a gel by mixing it with a gelling agent. One of the gelling agents that is often used is HPMC because it can produce a clear gel, easily soluble in water, and has low toxicity. Nyamplung oil has wound healing activity by stimulating cell proliferation and the production of collagen and GAG (glycosaminoglycans). The purpose of this study was to find out that nyamplung (Calophyllum inophyllum L) oil can be made into a good emulgel preparation, has the effect of healing cuts, to determine the effect of variations in HPMC concentration on the physical quality and stability of the emulgel, and in accelerating the healing of cuts. This study used three formulas containing 1%, 2%, and 3% HPMC plus one control formula. Emulgel is made by mixing emulsion with gel and contains 1% nyamplung oil, then physical quality tests are carried out : organoleptic, homogeneity, pH, adhesion, dispersibility, viscosity test, emulgel type test, stability test. The wound healing activity test was carried out on the back of New Zealand rabbits. The percentage of treatment results were statistically analyzed. The results showed that all nyamplung oil emulgel formulas could be made ini emulgel preparations, had good physical quality and stability and had the effect of wound healing. The effect of gelling agent concentration affects the speed of wound healing. The result of the most optimal wound healing activity test is the formula 2.
{"title":"Formulating Oil Emulgel of Nyamplung (Calophyllum inophyllum L) with Variations of HPMC and Activity Testing for Incision in Rabbit New Zealand","authors":"Erinda Risma Puspita Cahya, Dewi Ekowati, Dwi Ningsih","doi":"10.37311/ijpe.v2i3.15455","DOIUrl":"https://doi.org/10.37311/ijpe.v2i3.15455","url":null,"abstract":"Emulgel is an emulsion of both O/W and W/O which is made into a gel by mixing it with a gelling agent. One of the gelling agents that is often used is HPMC because it can produce a clear gel, easily soluble in water, and has low toxicity. Nyamplung oil has wound healing activity by stimulating cell proliferation and the production of collagen and GAG (glycosaminoglycans). The purpose of this study was to find out that nyamplung (Calophyllum inophyllum L) oil can be made into a good emulgel preparation, has the effect of healing cuts, to determine the effect of variations in HPMC concentration on the physical quality and stability of the emulgel, and in accelerating the healing of cuts. This study used three formulas containing 1%, 2%, and 3% HPMC plus one control formula. Emulgel is made by mixing emulsion with gel and contains 1% nyamplung oil, then physical quality tests are carried out : organoleptic, homogeneity, pH, adhesion, dispersibility, viscosity test, emulgel type test, stability test. The wound healing activity test was carried out on the back of New Zealand rabbits. The percentage of treatment results were statistically analyzed. The results showed that all nyamplung oil emulgel formulas could be made ini emulgel preparations, had good physical quality and stability and had the effect of wound healing. The effect of gelling agent concentration affects the speed of wound healing. The result of the most optimal wound healing activity test is the formula 2.","PeriodicalId":249696,"journal":{"name":"Indonesian Journal of Pharmaceutical Education","volume":"33 1-2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123601733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-17DOI: 10.37311/ijpe.v2i1.15855
Syahril Saini, Elvie Febriani Dungga, Ita Sulistiani
This article background about the availability of ishihara book is very rare in rural areas because of its quite expensive price. Therefore, in this current research, the researcher uses the Google Form-based ishihara book method which is relatively new which can make it easier to do a color blindness test. The research design employs an analytical survey method with a cross sectionl multisite study approach. The samples are 178 active students in 8th semester in faculties on campus 1 UNG where they are determined by accidental sampling. The research findings show that the color blindness test using ishihara book and google form is carried out on 178 (100%) active students in 8th semester of the total samples, 174 (97,7%) do not experience color blindness whereas 4 student (2,3%) have partial green color blindness. In conclusion, the results of evaluation of the sensitivity and specificity of google form towards the golden standard of ishihara book are 100% sensitivity and 100% specificity.
{"title":"Evaluasi Pemeriksaan Tes Buta Warna Menggunakan Metode Ishihara Berbasis Google Form Menggunakan Buku Ishihara","authors":"Syahril Saini, Elvie Febriani Dungga, Ita Sulistiani","doi":"10.37311/ijpe.v2i1.15855","DOIUrl":"https://doi.org/10.37311/ijpe.v2i1.15855","url":null,"abstract":"This article background about the availability of ishihara book is very rare in rural areas because of its quite expensive price. Therefore, in this current research, the researcher uses the Google Form-based ishihara book method which is relatively new which can make it easier to do a color blindness test. The research design employs an analytical survey method with a cross sectionl multisite study approach. The samples are 178 active students in 8th semester in faculties on campus 1 UNG where they are determined by accidental sampling. The research findings show that the color blindness test using ishihara book and google form is carried out on 178 (100%) active students in 8th semester of the total samples, 174 (97,7%) do not experience color blindness whereas 4 student (2,3%) have partial green color blindness. In conclusion, the results of evaluation of the sensitivity and specificity of google form towards the golden standard of ishihara book are 100% sensitivity and 100% specificity.","PeriodicalId":249696,"journal":{"name":"Indonesian Journal of Pharmaceutical Education","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132268304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.37311/ijpe.v2i2.15510
Aina Fatkhil haque, Elly Mulyani, Jimmy Hendick
Several studies have shown that cayenne pepper (Solanum frutescens.L) leaf extract has antimicrobial properties In this study, the extraction was carried out by the maceration method. The liquid soap formulation that will be made contains cayenne pepper leaf extract with 0.5%, 1%, 2%. Of all the parameters of the physical properties test carried out. It is known that the ethanol extract of cayenne pepper leaves can be made into liquid soap preparations. Variations in the concentration of ethanol extract of cayenne pepper leaves used in the study showed its effect on organoleptic tests in the form of color and aroma. In the pH test, the pH varied from 9.41-10.65 and the foam height obtained at the 5th minute was 91%, 92%, 93%. For the hedonic test, it was found that the panelists preferred Formula 2 to Formula 1 and Formula 3. Based on the results of the evaluation of the formulation, the best formula is obtained in formula 3.
{"title":"Formulasi Sabun Cair Cuci Tangan Antibakteri Ekstrak Etanol Daun Cabe Rawit (Solanum frutescens.L)","authors":"Aina Fatkhil haque, Elly Mulyani, Jimmy Hendick","doi":"10.37311/ijpe.v2i2.15510","DOIUrl":"https://doi.org/10.37311/ijpe.v2i2.15510","url":null,"abstract":"Several studies have shown that cayenne pepper (Solanum frutescens.L) leaf extract has antimicrobial properties In this study, the extraction was carried out by the maceration method. The liquid soap formulation that will be made contains cayenne pepper leaf extract with 0.5%, 1%, 2%. Of all the parameters of the physical properties test carried out. It is known that the ethanol extract of cayenne pepper leaves can be made into liquid soap preparations. Variations in the concentration of ethanol extract of cayenne pepper leaves used in the study showed its effect on organoleptic tests in the form of color and aroma. In the pH test, the pH varied from 9.41-10.65 and the foam height obtained at the 5th minute was 91%, 92%, 93%. For the hedonic test, it was found that the panelists preferred Formula 2 to Formula 1 and Formula 3. Based on the results of the evaluation of the formulation, the best formula is obtained in formula 3.","PeriodicalId":249696,"journal":{"name":"Indonesian Journal of Pharmaceutical Education","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126992720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-30DOI: 10.37311/ijpe.v2i3.15492
Elly Mulyani, H. Herlina, Dewi Winni Fauziah, Aina Fatkhil Haque
Bengkulu is a province that is in the top five as a coffee producer in the archipelago. The survey proves that Bengkulu has a fairly large potential for producing coffee with many local coffee products from Bengkulu city plantations that are already circulating in the market. Caffeine is a type of alkaloid found in coffee beans, tea leaves, and cocoa beans. This study aims to determine the caffeine content of Bengkulu plantations (Rejang Lebong, Kepahiang, Seluma) using Ultraviolet Spectrophotometry. The results showed that the coffee samples at the Bengkulu Plantation contained caffeine with levels, namely: 0,00144 mg (Seluma coffee sample), 0,011928 mg (Rejang Lebong coffee sample), 0,019,144 mg (Kepahiang coffee sample). Of the three data, the highest plantation caffeine content was found in Kepahiang coffee.
{"title":"Perbandingan Kadar Kafein pada Jenis Kopi Hasil Perkebunan Bengkulu dengan Metode Spektrofotometri Ultraviolet","authors":"Elly Mulyani, H. Herlina, Dewi Winni Fauziah, Aina Fatkhil Haque","doi":"10.37311/ijpe.v2i3.15492","DOIUrl":"https://doi.org/10.37311/ijpe.v2i3.15492","url":null,"abstract":"Bengkulu is a province that is in the top five as a coffee producer in the archipelago. The survey proves that Bengkulu has a fairly large potential for producing coffee with many local coffee products from Bengkulu city plantations that are already circulating in the market. Caffeine is a type of alkaloid found in coffee beans, tea leaves, and cocoa beans. This study aims to determine the caffeine content of Bengkulu plantations (Rejang Lebong, Kepahiang, Seluma) using Ultraviolet Spectrophotometry. The results showed that the coffee samples at the Bengkulu Plantation contained caffeine with levels, namely: 0,00144 mg (Seluma coffee sample), 0,011928 mg (Rejang Lebong coffee sample), 0,019,144 mg (Kepahiang coffee sample). Of the three data, the highest plantation caffeine content was found in Kepahiang coffee.","PeriodicalId":249696,"journal":{"name":"Indonesian Journal of Pharmaceutical Education","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115506241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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