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2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)最新文献

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A Portable Thermogram based Non-contact Non-invasive Early Breast-Cancer Screening Device 一种便携式非接触式非侵入性早期乳腺癌热像仪
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584762
Bilal Majeed, Hafiz Talha Iqbal, Uzair Khan, Muhammad Awais Bin Altaf
Thermogram (infrared) based non-contact noninvasive screening device for breast cancer is presented. To enable a home-based patient-comfort portable breast cancer screening device, a FLIR thermal imaging camera, with the best of four (BoF) features based on the proposed novel methodology and the support vector machine (SVM) learning classifier is exploited. The 4-dimensjon Feature Vector (FV) is computed using the segmented image, grey Level co-occurrence matrix (GLCM) and run-length matrix (RLM) calculation. To ensure hardware optimization, the proposed multiplexed GLCM, RLM and SVM implementation realizes an area reduction of 30% compared to the conventional with minimal overhead in the system speed requirement. A Linear SVM is utilized to decide between malignant and benign based on the FV. The system is implemented on FPGA and experimentally verified using the patients from the Mastological Research database. The proposed breast cancer screening processor targets a portable home environment and achieves the sensitivity and specificity of 79.06% and 88.57%, respectively.
介绍了一种基于红外热像仪的非接触式非侵入性乳腺癌筛查装置。为了实现家庭患者舒适的便携式乳腺癌筛查装置,利用基于所提出的新方法和支持向量机(SVM)学习分类器的四优(BoF)特征的FLIR热像仪。利用分割后的图像、灰度共生矩阵(GLCM)和行程矩阵(RLM)计算得到四维特征向量(FV)。为了确保硬件优化,本文提出的多路GLCM、RLM和SVM实现比传统方法减少了30%的面积,并且在系统速度要求方面的开销最小。基于FV,利用线性支持向量机进行良恶性判断。该系统在FPGA上实现,并利用乳腺研究数据库中的患者进行了实验验证。本文提出的乳腺癌筛查处理器针对便携式家庭环境,灵敏度和特异性分别达到79.06%和88.57%。
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引用次数: 9
Live Demonstration: A Bluetooth Low Energy (BLE)-enabled Wireless Link for Bidirectional Communications with a Neural Microsystem 现场演示:用于神经微系统双向通信的低功耗蓝牙(BLE)无线链路
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584703
Nicholas H. Vitale, M. Azin, P. Mohseni
This live demonstration showcases a fully interactive, Bluetooth low energy (BLE)-enabled, wireless interface for bidirectional communications with a neural microsystem. A standalone user base station (UBS) employs custom software to wirelessly communicate with the prototype microsystem via BLE. Users can seamlessly interact with the UBS to program and monitor various features and functions of the neural microsystem wirelessly over meter-range distances.
这个现场演示展示了一个完全交互式的、低功耗蓝牙(BLE)的无线接口,用于与神经微系统进行双向通信。一个独立的用户基站(UBS)使用定制软件通过BLE与原型微系统进行无线通信。用户可以与UBS无缝交互,在一米范围内无线编程和监控神经微系统的各种特征和功能。
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引用次数: 0
The Spectral Calibration of Swept-Source Optical Coherence Tomography Systems Using Unscented Kalman Filter 扫描源光学相干层析成像系统的无气味卡尔曼滤波光谱定标
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584823
A. T. Zavareh, S. Hoyos
The ever-increasing demand for acquiring images at a faster rate and consequently of deeper layers of tissue in swept-source optical coherence tomography (SS-OCT), has motivated researchers to investigate techniques capable of performing fast acquisition without compromising sensitivity. Non-linear spectral sweeps, phase instability, and increased noise levels of swept lasers can cause the image quality to deteriorate, especially if a lower quality light source is used. This work leverages the unscented Kalman filter aiming to alleviate these shortcomings. Using this filter, both the non-idealities of the non-linear sweep and the increased noise levels are accounted for. Simulations show promising performance results in terms of extracting the non-linear spectral sweep as a function of time. The UKF also shows better metrics compared to other versions of the Kalman filter when it comes to tracking non-linearities and hardware implementation complexity giving the method significant advantages in real-time applications of hand-held, portable optical coherence tomography devices.
在扫描源光学相干断层扫描(SS-OCT)中,以更快的速度获取图像和更深层次的组织的需求不断增长,促使研究人员研究能够在不影响灵敏度的情况下进行快速获取的技术。非线性光谱扫描、相位不稳定和扫描激光的噪声水平增加会导致图像质量恶化,特别是如果使用低质量的光源。这项工作利用无味卡尔曼滤波器旨在减轻这些缺点。使用这种滤波器,非线性扫描的非理想性和增加的噪声水平都被考虑在内。仿真结果表明,该方法在提取随时间变化的非线性谱扫描信号方面取得了良好的性能。与其他版本的卡尔曼滤波器相比,UKF在跟踪非线性和硬件实现复杂性方面也表现出更好的指标,这使得该方法在手持、便携式光学相干断层扫描设备的实时应用中具有显著优势。
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引用次数: 2
A Neuromorphic Computing System for Bitwise Neural Networks Based on ReRAM Synaptic Array 基于ReRAM突触阵列的位神经网络神经形态计算系统
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584810
Pin-Yi Li, Cheng-Han Yang, Wei-Hao Chen, Jian-Hao Huang, Wei-Chen Wei, Je-Syu Liu, Wei-Yu Lin, Tzu-Hsiang Hsu, C. Hsieh, Ren-Shuo Liu, Meng-Fan Chang, K. Tang
Recent advances in neuromorphic computing system have shown resistive random-access memory (ReRAM) can be used to efficiently implement compact parallel computing arrays, which are inherently suitable for neural networks that require large amounts of matrix-vector multiplications (MVMs). In this work, we proposed a neuromorphic computing system based on ReRAM synaptic array to implement bitwise neural networks. The system contains a ReRAM synaptic array for parallel computation of bitwise MVMs, and a field-programmable gate array for data buffering and processing. To deploy the network on the system, a customized training scheme was required to adapt the trained network to the characteristic of ReRAM synaptic array with bitwise weights and inputs. We also managed the resolution of partial sum to reduce the bit width requirement of sense amplifier, thereby reducing power consumption. The measurement results show that the ReRAM synaptic array consumed only 0.27mW at 1V supply by using 1-bit sense amplifier while the system still maintained 97.52% accuracy on MNIST dataset.
神经形态计算系统的最新进展表明,电阻式随机存取存储器(ReRAM)可以有效地实现紧凑的并行计算阵列,这本质上适用于需要大量矩阵向量乘法(MVMs)的神经网络。在这项工作中,我们提出了一种基于ReRAM突触阵列的神经形态计算系统来实现位神经网络。该系统包含一个用于位mvm并行计算的ReRAM突触阵列和一个用于数据缓冲和处理的现场可编程门阵列。为了在系统上部署网络,需要定制训练方案,使训练后的网络适应具有位权和输入的ReRAM突触阵列的特性。我们还对部分和的分辨率进行了管理,以降低感测放大器的位宽要求,从而降低功耗。测量结果表明,采用1位感测放大器的ReRAM突触阵列在1V供电时功耗仅为0.27mW,而系统在MNIST数据集上仍保持97.52%的准确率。
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引用次数: 2
Muscle Synergy Adaptation During A Complex Postural Stabilization Task* 在复杂的姿势稳定任务中的肌肉协同适应*
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584801
Rajat Emanuel Singh, K. Iqbal, G. White
The organization of encoded motor modules or motor primitives in the central nervous system and their combination leads to different aspects of natural motor behavior. It is believed that neural stimulation of these coded sections activates specific groups of muscles to achieve a behavioral goal. We use the muscle synergy (MS) hypothesis to compare activation patterns during overground walking and slackline walking for a small group of highly proficient slackliners and beginners. Synchronous MS were extracted using factor analysis (FA) for rhythmic and arrhythmic repertoire of movement. The results revealed no significant difference between slackliners and non-slackliners as the extracted synergies were dependent on the variability of the task. Besides, the shared dimensional space revealed the task-specific higher loading of the quadriceps muscles for walking with such postural constraints.
中枢神经系统中编码运动模块或运动原语的组织及其组合导致自然运动行为的不同方面。据信,对这些编码部分的神经刺激会激活特定的肌肉群,以达到行为目标。我们使用肌肉协同(MS)假说来比较一小群高度熟练的松弛者和初学者在地上行走和走软绳时的激活模式。同步质谱提取采用因子分析(FA)的节奏和无节奏的动作曲目。结果显示,懒散者和非懒散者之间没有显著差异,因为提取的协同效应取决于任务的可变性。此外,共享维度空间揭示了在这种姿势限制下行走时股四头肌的任务特异性更高负荷。
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引用次数: 6
Live Demonstration: 385 × 385 μm2 0.165V 270pW Fully-Integrated Supply-Modulated OOK Tx in 65nm CMOS for Glasses-Free, Self-Powered, and Fuel-Cell-Embedded Continuous Glucose Monitoring Contact Lens 现场演示:385 × 385 μm2 0.165V 270pW全集成电源调制OOK Tx在65nm CMOS无眼镜,自供电,和嵌入燃料电池连续血糖监测隐形眼镜
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584841
K. Hayashi, S. Arata, Ge Xu, S. Murakami, C. D. Bui, A. Kobayashi, K. Niitsu
In order to care and prevent diabetes, continuous glucose monitoring (CGM) is considerably important [1]. However, existing needle-type glucose monitoring systems [2] are painful, thus unsuitable for preventing applications. In order to address this issue, a needle-less and pain-free CGM contact lens has been developed [3]. Since tear glucose level has high correlation with blood glucose level, it can be expected to be future de facto standard CGM. However, the existing CGM contact lens is based on RFID technology associated with the dedicated smart glasses, which degrade the patients' comfort and cost too much.
为了护理和预防糖尿病,连续血糖监测(continuous glucose monitoring, CGM)非常重要[1]。然而,现有的针式血糖监测系统[2]是痛苦的,因此不适合预防应用。为了解决这一问题,一种无针无痛的CGM隐形眼镜被开发出来[3]。由于泪液葡萄糖水平与血糖水平高度相关,因此可以预期它将成为未来事实上的标准CGM。然而,现有的CGM隐形眼镜是基于RFID技术与专用智能眼镜相结合,降低了患者的舒适度,且成本过高。
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引用次数: 1
Toward an Energy-Efficient Bridge-to-Digital Intracranial Pressure Sensing Interface 一种高能效的桥-数字颅内压传感接口
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584771
Ahmad Rezvanitabar, Gwangrok Jung, F. Degertekin, Maysam Ghovanloo
This work presents an integrated solution for lowering the power consumption in interface circuits for bridge sensors, which consume power because of their low resistances particularly in implantable microsystems, such as intracranial pressure (ICP) monitoring application. The proposed direct bridge-to-digital interface uses a pseudo-pseudo differential (PPD) structure, in which the converter not only provides key benefits of traditional fully-differential interface circuits but also can reduce their complexity with single-ended architecture. It occupies 0.0667 mm2in 0.35-μm standard CMOS technology, where the interface provides 9.13 effective number of bits (ENOB), while cutting the power consumption of a 3 kΩWheatstone bridge down to 363 µW at 1.8 V supply, and sampling rate of 3.72 kHz in post-layout simulations.
这项工作提出了一种降低桥式传感器接口电路功耗的集成解决方案,桥式传感器由于其低电阻而消耗功耗,特别是在可植入微系统中,如颅内压(ICP)监测应用。所提出的直接桥接数字接口采用伪伪差分(PPD)结构,该转换器不仅具有传统全差分接口电路的主要优点,而且可以降低其单端结构的复杂性。它采用0.0667 mm2in 0.35 μm标准CMOS技术,其接口提供9.13有效位数(ENOB),同时在1.8 V电源下将3 kΩWheatstone电桥的功耗降低至363µW,在布局后仿真中采样率为3.72 kHz。
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引用次数: 2
Early Detection of Epileptic Activity on EEG Signals using Phase-Preserving Quantization Method 用保相量化方法早期检测脑电图信号的癫痫活动
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584766
Sylmarie Dávila-Montero, E. Ashoori, A. Mason
This paper demonstrates the use of a data decimation method, called phase-preserving quantization (PPQ), for early seizure prediction. PPQ consists of a) amplifying and filtering the neural signals around the frequency band of interest, and b) compressing the filtered signal using a 1-bit quantizer with a 0-V single-threshold decision. The ability of PPQ to retain phase information and predict seizure events while compressing the signal resolution to a single bit is demonstrated using electroencephalography (EEG) recordings from the Children's Hospital Boston-MIT (CHB-MIT) EEG database. Results show 97% accuracy when calculating synchrony values using PPQ, which is an improvement of 7% when compared to previously published results. The presented improved method enables the early detection of seizure events, resulting in a decrease in phase synchrony computation time while allowing an increase in the number of recording channels that can be screened when using EEG.
本文演示了一种数据抽取方法,称为保相量化(PPQ),用于早期癫痫发作预测。PPQ包括a)在感兴趣的频带周围放大和滤波神经信号,以及b)使用0-V单阈值判决的1位量化器压缩滤波后的信号。利用来自波士顿-麻省理工学院儿童医院脑电图数据库的脑电图记录,证明了PPQ在将信号分辨率压缩到单个比特的同时保留相位信息和预测癫痫事件的能力。结果显示,在使用PPQ计算同步值时,准确度为97%,与之前发表的结果相比,提高了7%。提出的改进方法能够早期检测到癫痫事件,从而减少了相位同步计算时间,同时增加了使用EEG时可以筛选的记录通道的数量。
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引用次数: 1
Highly-Stretchable Biomechanical Strain Sensor using Printed Liquid Metal Paste 使用印刷液态金属膏体的高可拉伸生物力学应变传感器
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584671
Callen Votzke, U. Daalkhaijav, Y. Mengüç, M. Johnston
Stretchable electronic circuits and systems will be critical for future wearable devices and smart textiles, where existing rigid and flexible fabrication approaches severely limit conformal deformation. This is especially true for wearable sensors and actuators, critical for emerging physical human-machine interfaces and stretchable electrical interconnects. In this work, we present a 3D-printed, highly-stretchable strain sensor that uses a modified liquid metal paste to provide high-strain conductors. This approach provides near-zero hysteresis compared with nanotube-based inks, and improved conductivity over carbon- and metal-based inks, both critical for integration of soft sensors with stretchable measurement circuitry. We present an approach for fabrication of the wearable sensors and demonstrate stable conductivity of the liquid metal paste with near-zero hysteresis over 375 cycles at 200% strain. The device is demonstrated for measurement of elbow flexion angle, providing proof-of-concept of the approach for biomechanical sensor applications and wearable human-machine interfaces.
可拉伸电子电路和系统对未来的可穿戴设备和智能纺织品至关重要,现有的刚性和柔性制造方法严重限制了保形变形。对于可穿戴传感器和执行器来说尤其如此,这对于新兴的物理人机界面和可拉伸的电气互连至关重要。在这项工作中,我们提出了一种3d打印的,高度可拉伸的应变传感器,它使用改性液态金属糊状物来提供高应变导体。与基于纳米管的油墨相比,这种方法提供了接近零的滞后,并且优于碳基和金属基油墨的导电性,这对于软传感器与可拉伸测量电路的集成至关重要。我们提出了一种制造可穿戴传感器的方法,并证明了液态金属膏体在200%应变下的375次循环中具有接近零迟滞的稳定电导率。该设备用于测量肘关节弯曲角度,为生物力学传感器应用和可穿戴人机界面提供了概念验证。
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引用次数: 19
Energy-Optimal Gesture Recognition using Self-Powered Wearable Devices 使用自供电可穿戴设备的能量优化手势识别
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584746
Jaehyun Park, Ganapati Bhat, C. S. Geyik, Ümit Y. Ogras, H. Lee
Small form factor and low-cost wearable devices enable a variety of applications including gesture recognition, health monitoring, and activity tracking. Energy harvesting and optimal energy management are critical for the adoption of these devices, since they are severely constrained by battery capacity. This paper considers optimal gesture recognition using self-powered devices. We propose an approach to maximize the number of gestures that can be recognized under energy budget and accuracy constraints. We construct a computationally efficient optimization algorithm with the help of analytical models derived using the energy consumption breakdown of a wearable device. Our empirical evaluations demonstrate up to 2.4 x increase in the number of recognized gestures compared to a manually optimized solution.
小尺寸和低成本的可穿戴设备支持各种应用,包括手势识别、健康监测和活动跟踪。能量收集和最佳能量管理对于这些设备的采用至关重要,因为它们受到电池容量的严重限制。本文考虑了使用自供电设备的最佳手势识别。我们提出了一种在能量预算和精度限制下可以识别的手势数量最大化的方法。我们利用可穿戴设备的能量消耗分解导出的分析模型构建了一个计算效率高的优化算法。我们的经验评估表明,与手动优化的解决方案相比,识别手势的数量增加了2.4倍。
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引用次数: 5
期刊
2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)
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