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Developing Resources for Staff and Adapting Programing During COVID-19 at Fred Victor 为员工开发资源并在2019冠状病毒病期间调整规划
Pub Date : 2021-09-27 DOI: 10.33137/utjph.v2i2.36835
Claire Carnegie
Fred Victor is an organization that supports those experiencing poverty and homelessness in Toronto. As a practicum student in the Health Promotions department at Fred Victor, I gained experience working on health promotion projects and was able to work directly with the community. Throughout the practicum, I worked on several projects to adapt Fred Victor’s services during COVID-19. First, I worked to develop a resilience toolkit for Fred Victor staff. COVID-19 has led to higher levels of stress. This prompted Fred Victor to develop tools to support their staff. I designed a toolkit that instructs managers on how to promote resilience in their supervision sessions and team meetings. This toolkit provided information on what resilience is, as well as practical actions that managers can take to promote resilience in staff. This project involved knowledge translation to convey the research on resilience to Fred Victor staff in an accessible way. Additionally, I worked to support the development of online peer support groups. Typically, Fred Victor runs weekly in-person peer support groups for community members. However, due to COVID-19, these groups had to move to an online format. I helped facilitate this transition by developing a guide for facilitating online group programming. This guide included information on the best platforms to run online programming, how to create a safety agreement, and best practices for facilitating the group. I then conducted outreach to community members to ask for their input on the format and content of the groups. These projects are important to public health as they work to meet the public health goal to improve quality of life by promoting and encouraging healthy behaviours. These projects played an important role in promoting the health of Fred Victor staff and clients during COVID-19 by providing them with support and tools to manage their mental health.
Fred Victor是一个支持多伦多贫困和无家可归者的组织。作为Fred Victor健康促进部门的实习学生,我获得了从事健康促进项目的经验,并能够直接与社区合作。在整个实习期间,我参与了几个项目,以适应弗雷德·维克多在COVID-19期间的服务。首先,我为弗雷德·维克多的员工开发了一个弹性工具包。COVID-19导致了更大的压力。这促使Fred Victor开发工具来支持他们的员工。我设计了一个工具包,指导经理们如何在监督会议和团队会议上提高弹性。这个工具包提供了关于什么是弹性的信息,以及管理者可以采取的实际行动,以促进员工的弹性。该项目涉及知识翻译,以一种易于理解的方式向弗雷德维克多的员工传达对弹性的研究。此外,我还致力于支持在线同伴支持小组的发展。通常,弗雷德·维克多每周都会为社区成员举办面对面的同伴支持小组。然而,由于2019冠状病毒病,这些团体不得不转向在线形式。我通过开发一个促进在线小组编程的指南来帮助促进这种转变。该指南包括运行在线节目的最佳平台,如何创建安全协议以及促进小组的最佳实践等信息。然后,我向社区成员征求他们对小组形式和内容的意见。这些项目对公共卫生很重要,因为它们致力于通过促进和鼓励健康行为来实现改善生活质量的公共卫生目标。在2019冠状病毒病疫情期间,这些项目为Fred Victor员工和客户提供了管理心理健康的支持和工具,在促进他们的健康方面发挥了重要作用。
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引用次数: 0
Epigenetics of skin intrinsic florescence 皮肤固有荧光的表观遗传学
Pub Date : 2021-09-27 DOI: 10.33137/utjph.v2i2.36843
Jiamin Guo, Andrew Paterson, D. Roshandel
Introduction & Objective: Cumulated advanced glycation end products (AGEs) in the bloodstream and tissues contribute to the pathogenesis of diabetes complications. The skin intrinsic fluorescence (SIF) is a non-invasive measurement of dermal AGEs level using spectrometer, and it can be used as a biomarker in AGEs-related diseases. Previously, specific epigenomic factor has been found to be associated with haemoglobin A1c (HbA1c). HbA1c is a type of glycated haemoglobin – the HbA1c test measures the average glycemic control over the period of 3 months. However, the effect of epigenetic factors on the level of AGEs in the skin remains unknown. We hypothesize that some cytosine-guanine dinucleotides (CpGs) are associated with SIF. An epigenome-wide associations study (EWAS) was performed to identify CpG sites associated with SIF in people with type 1 diabetes. Methods: 499 people with type 1 diabetes that have both methylation and SIF from the Diabetes Control Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study were included. We fit linear regression models for SIF with each CpG site one at a time. The epigenome-wide significance level (p=5e-8) was applied. Then the result is compared with the null hypothesis where CpGs are not associated with SIF to check the inflation. In order to check the assumptions of the multiple linear models at a single CpG, we use diagnostic plots. Results: We did not identify a specific CpG that is significantly associated with neither skin intrinsic fluorescence 1 (SIF1) nor skin intrinsic fluorescence 12 (SIF 12).The CpG site with strongest effect is cg06538183 ([SE] -2.73 [0.61], p = 8.72e-6) on SIF1 and cg12871967 ([SE] 2.52, 0.53, p = 2.71e-6) on SIF12. Conclusion: We did not find any specific CpG that was significantly associated with either SIF 1 or SIF12. In general, the result suggests that DNA methylation does not impact the accumulation of AGEs in skin cells. DNA methylation data has a unique pattern of distribution that drives the non-uniform distribution of the p-values. The group of 275,301 CpGs that have means above the median and standard deviations below the median has the expected uniform p-value distribution.
简介与目的:血液和组织中累积的晚期糖基化终产物(AGEs)有助于糖尿病并发症的发病。皮肤本征荧光(SIF)是一种利用分光计无创测量皮肤AGEs水平的方法,可作为AGEs相关疾病的生物标志物。以前,已经发现特定的表观基因组因子与血红蛋白A1c (HbA1c)相关。糖化血红蛋白是一种糖化血红蛋白——糖化血红蛋白测试测量的是3个月的平均血糖控制水平。然而,表观遗传因素对皮肤中AGEs水平的影响尚不清楚。我们假设一些胞嘧啶-鸟嘌呤二核苷酸(CpGs)与SIF有关。进行了一项全表观基因组关联研究(EWAS),以确定与1型糖尿病患者SIF相关的CpG位点。方法:纳入糖尿病控制并发症试验/糖尿病干预和并发症流行病学(DCCT/EDIC)研究中同时存在甲基化和SIF的499例1型糖尿病患者。我们将SIF的线性回归模型与每个CpG位点一次拟合一个。采用全表观基因组显著性水平(p=5e-8)。然后将结果与零假设进行比较,其中CpGs与SIF无关,以检查通货膨胀。为了检验多个线性模型在单个CpG下的假设,我们使用诊断图。结果:我们没有发现特异性CpG与皮肤固有荧光1 (SIF1)和皮肤固有荧光12 (sif12)都没有显著相关。影响最强的CpG位点为SIF1上的cg06538183 ([SE] -2.73 [0.61], p = 8.72e-6)和SIF12上的cg12871967 ([SE] 2.52, 0.53, p = 2.71e-6)。结论:我们没有发现任何特定的CpG与sif1或SIF12显著相关。总的来说,结果表明DNA甲基化不会影响皮肤细胞中AGEs的积累。DNA甲基化数据具有独特的分布模式,驱动p值的非均匀分布。均值高于中位数且标准差低于中位数的275,301个cpg组具有期望的均匀p值分布。
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引用次数: 0
Translations for Our Nations: Addressing the Indigenous Language Gap in COVID-19 Health Communication 为我们的国家翻译:解决COVID-19卫生传播中的土著语言差距
Pub Date : 2021-09-27 DOI: 10.33137/utjph.v2i2.36897
Thilaxcy Yohathasan, Sterling Stutz
Purpose: The availability of culturally safe and plain-language resources is necessary to reduce the spread of COVID-19 for Indigenous communities around the world. Translations For Our Nations is an initiative addressing these resource gaps, making available COVID-19 health resources in Indigenous languages on the web. The project began in April 2020 as a result of the Indigenous COVID-19 Health Partnership launched by Victor A. Lopez-Carmen, a Dakota and Yaqui medical student, Harvard Medical School) and co-founded by Sterling Stutz and Thilaxcy Yohathasan, (MPH-Indigenous Health at the University of Toronto), and Sukhmeet Singh Sachal (medical student, University of British Columbia). Methods: Translators from Indigenous communities around the world signed up to participate in the project via a GoogleForm in April 2020. Over 100 Indigenous translators and community members in regions (South America, Asia, Africa, Europe, North America, and the Pacific) were provided the 5 English language source materials reviewed by physicians and Indigenous youth leaders. Translators submitted their translated documents via email and on September 1, 2020 the website Translations4OurNations.org was launched where the translated documents can be accessed and downloaded with more translations accepted on a rolling basis. Results: Translations for our Nations has published COVID-19 health resources in 40+ Indigenous languages from around the world. The website also includes photos and text submissions from community members speaking to the importance of culturally-specific COVID-19 health information disseminated directly to communities in local languages and dialects. Implications:  Indigenous Nations have the right to access vital health information in their mother tongue. This project is led by and designed for Indigenous youth and Indigenous community members to empower individuals and communities to make informed choices regarding their health and exposure risks, and decrease the risk of COVID-19 transmission in Indigenous communities around the world.
目的:提供文化上安全和语言简单的资源对于减少COVID-19在世界各地土著社区的传播是必要的。“为我们的国家翻译”是一项解决这些资源缺口的倡议,在网络上提供土著语言的COVID-19卫生资源。该项目于2020年4月启动,是由哈佛医学院达科他和雅基医科学生Victor a . Lopez-Carmen发起的土著COVID-19卫生伙伴关系的结果,该伙伴关系由Sterling Stutz和Thilaxcy Yohathasan(多伦多大学土著卫生硕士)和Sukhmeet Singh Sachal(不列颠哥伦比亚大学医科学生)共同创立。方法:来自世界各地土著社区的翻译人员于2020年4月通过GoogleForm报名参加该项目。来自各地区(南美、亚洲、非洲、欧洲、北美和太平洋)的100多名土著翻译人员和社区成员获得了由医生和土著青年领袖审查的5种英语源材料。翻译人员通过电子邮件提交翻译文件,并于2020年9月1日启动了Translations4OurNations.org网站,可以访问和下载翻译文件,并以滚动方式接受更多翻译。结果:翻译为我们的国家出版了来自世界各地的40多种土著语言的COVID-19卫生资源。该网站还包括社区成员提交的照片和文字,说明以当地语言和方言直接向社区传播具有文化特殊性的COVID-19卫生信息的重要性。影响:土著民族有权以其母语获取重要的卫生信息。该项目由土著青年和土著社区成员领导,旨在使个人和社区能够就其健康和暴露风险做出知情选择,并降低COVID-19在世界各地土著社区传播的风险。
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引用次数: 0
Evaluating the Impact of Alcohol Control Interventions on Suicide Mortality Rates 评估酒精控制干预措施对自杀死亡率的影响
Pub Date : 2021-09-27 DOI: 10.33137/utjph.v2i2.36827
Xinyang Feng, Huan Jiang
Introduction & Objective: Given that the impact of regulatory and public policy initiatives cannot usually be tested through traditional randomized controlled trial designs, well-selected, -designed, and -analyzed natural experiments are the method of choice when examining the effects of such enactments on a variety of outcomes. The classic methodology for such evaluations is interrupted time-series (ITS) analysis, which is considered as one of the quasi-experimental designs that use both pre- and post-policy data without randomization. This study tests the impact of alcohol control interventions implemented in different period of times on suicide mortality rates among people 25-74 years of age using ITS. Methods: We mainly use the generalized additive mixed model (GAMM) to capture trend and seasonality in suicide mortality rates while controlling for unemployment rates, financial crisis during 2007-2008, and legal alcohol consumption records. Given the notable differences in alcohol consumption and suicide mortality between males and females, all analyses are conducted gender-specifically. Results: The ITS shows that the intervention introduced in 2017 has a significant effect on reducing suicide mortality rates for males between 25 and 74. Following the implementation of the intervention, suicide mortality rates decreased by 23.8% (95% CI: 10.2% - 35.4%) on average. Conclusion: The alcohol control intervention that strictly increased the excise tax on alcohol products has been shown to have a strong impact on reducing suicide mortality rates among male adults 25-74 years of age. ITS analyses are one of the strongest evaluative designs and allow a more detailed assessment of the longitudinal impact of an intervention than may be possible with a randomized control trial.
引言与目标:鉴于监管和公共政策举措的影响通常不能通过传统的随机对照试验设计来测试,因此,在检查此类颁布对各种结果的影响时,精心选择,设计和分析的自然实验是首选方法。这种评估的经典方法是中断时间序列(ITS)分析,它被认为是一种准实验设计,同时使用政策前和政策后的数据,没有随机化。本研究测试了不同时期实施的酒精控制干预措施对使用ITS的25-74岁人群自杀死亡率的影响。方法:在控制失业率、2007-2008年金融危机和合法饮酒记录的情况下,主要采用广义加性混合模型(GAMM)捕捉自杀死亡率的趋势和季节性。鉴于男性和女性在饮酒量和自杀死亡率方面的显著差异,所有分析都是针对性别进行的。结果:ITS显示,2017年引入的干预措施对降低25 - 74岁男性自杀死亡率有显著效果。实施干预后,自杀死亡率平均下降23.8%(95%置信区间:10.2% - 35.4%)。结论:严格提高酒精产品消费税的酒精控制干预措施已被证明对降低25-74岁男性成年人的自杀死亡率有很大影响。ITS分析是最强的评价设计之一,与随机对照试验相比,它允许对干预措施的纵向影响进行更详细的评估。
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引用次数: 0
Impact of COVID-19 on displaced populations and migrants around the world COVID-19对世界各地流离失所人口和移民的影响
Pub Date : 2021-09-27 DOI: 10.33137/utjph.v2i2.36896
Alifa Siddiqui
My practicum placement was completed with the Dalla Lana School of Public Health Centre for Global Health. I have contributed to the work of a team of student and faculty members developing a review of the literature and environmental scan to explore the impact of the COVID-19 pandemic on migrant populations. I worked with colleagues to design and run a search strategy on the Medline (OVID) and Scopus bibliographic databases. The findings showed that crises including the COVID-19 pandemic act as magnifying lens and expose existing inequities within society as the impact of the pandemic is not equally felt by all population groups. Migrant populations are particularly impacted due to their intersectional identities that marginalize and disempower them and severely impact their health outcomes. Even though migration is the engine of the globalized economy and migrant workers make significant contribution to agricultural and economic prosperity, their precarious living conditions have worsened during the pandemic and they are being excluded from relief packages and income support. Furthermore, racism and xenophobia are fuelling hostility and prejudice towards migrants as governments are controlling the movement of migrants by closing their borders to asylum seekers and existing refugee camps are having outbreaks due to cramped and overcrowded living conditions and limited healthcare access. It is evident that migrant populations are very diverse groups that are facing unique challenges and thus, require distinct forms of protection particularly during this pandemic. The results of this work are currently being summarized in a manuscript that recognizes how determinants of health impact the health and well-being of migrants, the need to develop a road map for recovery using a health equity lens, and inform health policies. To eradicate COVID-19, it is imperative to leave no one behind including migrant populations and re-evaluate how inequities are addressed globally.
我的实习是在达拉拉纳公共卫生学院全球卫生中心完成的。我为一个由学生和教师组成的团队的工作做出了贡献,该团队正在对文献和环境扫描进行审查,以探索COVID-19大流行对移民人口的影响。我和同事一起设计并运行了Medline (OVID)和Scopus书目数据库的搜索策略。调查结果表明,包括COVID-19大流行在内的危机是放大镜,暴露了社会中现有的不平等现象,因为大流行的影响并不是所有人群都能平等地感受到。移徙人口受到的影响特别大,因为他们的交叉身份使他们被边缘化和丧失权力,并严重影响到他们的健康结果。尽管移徙是全球化经济的引擎,移徙工人对农业和经济繁荣作出了重大贡献,但他们不稳定的生活条件在大流行病期间恶化了,他们被排除在一揽子救济计划和收入支助之外。此外,种族主义和仇外心理加剧了对移徙者的敌意和偏见,因为各国政府正在通过对寻求庇护者关闭边界来控制移徙者的流动,现有难民营由于生活条件拥挤和过度拥挤以及获得医疗保健的机会有限而爆发疫情。显然,移民人口是非常多样化的群体,他们面临着独特的挑战,因此需要不同形式的保护,特别是在这场大流行病期间。目前,这项工作的成果总结在一份手稿中,其中认识到健康的决定因素如何影响移徙者的健康和福祉,需要从卫生公平的角度制定恢复路线图,并为卫生政策提供信息。要根除COVID-19,必须不让任何一个人掉队,包括移民人口,并重新评估如何在全球范围内解决不平等问题。
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引用次数: 0
Exploring Frontline Healthcare Worker's Stress and Recovery Off-Shift during the COVID-19 Pandemic COVID-19大流行期间一线医护人员的压力与下班恢复
Pub Date : 2021-09-27 DOI: 10.33137/utjph.v2i2.36841
Hoora Emami
I completed my practicum with 4YouandMe, a non-profit created to aid individuals who are interested in sharing health-related data using smartphones and other wearable devices so that they can better understand and navigate health conditions. The Stress and Recovery Study used the Oura ring and smartphones to track and understand the multidimensional components of stress and recovery off-shift in frontline healthcare workers during the current COVID-19 pandemic. My role in this study was actively working as a clinical research coordinator and digital participant engagement expert. This role consisted of calling participants and asking them about their overall study experience, details regarding their stress triggers, their home and work environments, and use of their Oura ring. I was responsible for maintaining contact with about 70 participants and creating contact logs after each phone call. The purpose of these phone calls is to provide support and encourage participant adherence to the study tasks. In addition to this primary role, I also completed an emerging COVID-19 hotspot map that was used in the recruitment process of the study. I outlined regions in the U.S that may become hotspots for COVID cases and may subsequently translate to a higher stressed group of healthcare workers in those areas. Additionally, I contributed to developing adherence tracking frameworks and other study materials used by team members. This study is contributing to the public health literature by using novel methodologies including digital approaches to understanding stress. Looking at digital stress responses and biometric data as signals to predict infection may inform other tools to aid in early detection.  Finally, the study aims to determine whether resiliency factors and some social determinants of health modify stress and recovery.
我在4YouandMe完成了我的实习。4YouandMe是一家非营利机构,旨在帮助那些有兴趣使用智能手机和其他可穿戴设备共享健康数据的个人,以便他们更好地了解和驾驭健康状况。压力与恢复研究使用Oura环和智能手机来跟踪和了解当前COVID-19大流行期间一线医护人员的压力和恢复的多维组成部分。我在这项研究中的角色是作为临床研究协调员和数字参与者参与专家积极工作。这个角色包括打电话给参与者,询问他们的整体学习经历,他们的压力触发因素的细节,他们的家庭和工作环境,以及他们的Oura戒指的使用情况。我负责与大约70名参与者保持联系,并在每次通话后创建联系人记录。这些电话的目的是提供支持和鼓励参与者坚持研究任务。除了这个主要角色,我还完成了一个新冠病毒热点地图,用于研究的招募过程。我概述了美国可能成为COVID病例热点的地区,并可能随后转化为这些地区医护人员压力更大的群体。此外,我还为开发依从性跟踪框架和团队成员使用的其他学习材料做出了贡献。这项研究通过使用包括数字方法在内的新方法来理解压力,为公共卫生文献做出了贡献。将数字应激反应和生物特征数据作为预测感染的信号,可以为其他工具提供帮助,以帮助早期发现。最后,该研究旨在确定弹性因素和健康的一些社会决定因素是否会改变压力和恢复。
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引用次数: 0
Predicting Methicillin-Resistant Staphylococcus aureus (MRSA) Bloodstream Infection Incidence Rates using Canadian Nosocomial Infection Surveillance Program (CNISP) 利用加拿大医院感染监测项目(CNISP)预测耐甲氧西林金黄色葡萄球菌(MRSA)血流感染发生率
Pub Date : 2021-09-27 DOI: 10.33137/utjph.v2i2.36999
Jona Gjevori, K. Abdesselam
Methicillin-Resistant Staphylococcus aureus (MRSA) is among the most prevalent nosocomial pathogens globally, causing significant morbidity, mortality, and healthcare costs. MRSA bloodstream infection (BSI) incidence rates in Canadian hospitals have significantly risen by almost 60% and have a mortality of over 20% upon Intensive Care Unit admission. MRSA is believed to be spread through healthcare workers; thus, high hand hygiene compliancy in addition to environmental cleaning are the cornerstone countermeasures to disrupting its transmission. The Public Health Agency of Canada (PHAC), in collaboration with the Canadian Nosocomial Infection Surveillance Program (CNISP), conducts national, sentinel surveillance on healthcare-associated infections like MRSA. As a Student Epidemiologist, I developed a research proposal detailing two study objectives: 1) develop a regression model to predict all incident MRSA BSI rates among acute-care hospitals in Canada using CNISP MRSA BSI incident cases from 2000 to 2019, and 2) create a compartmental (Susceptible-Infected-Recovered-Deceased) model to determine the impact of various Infection Prevention and Control (IPC) measures on the risk of healthcare-associated MRSA BSI transmission specifically. This study hopes to demonstrate that proper IPC compliance is associated with lower incident MRSA BSI rates with the goal being to produce a manuscript draft by 2021. MRSA poses a serious threat to patient safety globally and is becoming a growing national public health concern in Canada; determining which IPC strategy is most effective at disrupting MRSA transmission is essential to reducing incidence and mortality rates.
耐甲氧西林金黄色葡萄球菌(MRSA)是全球最普遍的医院病原菌之一,造成严重的发病率、死亡率和医疗费用。MRSA血液感染(BSI)在加拿大医院的发病率显著上升了近60%,重症监护病房入院时死亡率超过20%。据信耐甲氧西林金黄色葡萄球菌是通过医护人员传播的;因此,除了环境清洁外,严格遵守手部卫生是破坏其传播的基本对策。加拿大公共卫生署(PHAC)与加拿大医院感染监测计划(CNISP)合作,对与医疗保健相关的感染(如MRSA)进行全国性哨点监测。作为一名学生流行病学家,我制定了一项研究计划,详细说明了两个研究目标:1)利用2000年至2019年的CNISP MRSA BSI事件病例,建立一个回归模型,以预测加拿大急症医院中所有MRSA BSI事件的发生率;2)创建一个分区(易感-感染-康复-死亡)模型,以确定各种感染预防和控制(IPC)措施对医疗保健相关MRSA BSI传播风险的影响。本研究希望证明适当的IPC合规性与较低的MRSA BSI发生率相关,目标是在2021年之前产生手稿草案。MRSA对全球患者安全构成严重威胁,并正在成为加拿大日益严重的国家公共卫生问题;确定哪种IPC策略在阻断MRSA传播方面最有效,对于降低发病率和死亡率至关重要。
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引用次数: 1
Examining prevalence of cancer risk factors across Ontario for the Ontario Cancer Profiles tool 为安大略省癌症概况工具检查安大略省癌症风险因素的流行情况
Pub Date : 2021-09-27 DOI: 10.33137/utjph.v2i2.36838
Amy Chang, N. Schwartz, R. Truscott
The Ontario Cancer Profiles is an interactive dashboard for the public containing population-level cancerstatistics created by Ontario Health (Cancer Care Ontario). The tool contains data on cancer burden, cancerscreening measures, and cancer risk factors by Local Health Integration Network (LHIN) and Public Health Unit (PHU). It can be used for health system planning, measuring health systems performance, monitoring the impact of interventions, and to help identify new areas of research. There were 9 new modifiable cancer risk factors proposed to be included in future updates of the dashboard. The proposed risk factors include: access to care, active transportation, binge drinking, alcohol abstinence, inadequate fruit consumption, inadequate vegetable consumption, sedentary behaviour, second-hand smoke exposure, and sun safety. My practicum consisted of two main objectives: to conduct a literature review on the association between the proposed risk factors and cancer and to determine the prevalence of exposure of the identified risk factors in Ontario using 2015 to 2017 CCHS data. I performed a literature review to examine current evidence linking each proposed risk factor with cancer risk to determine the inclusion or exclusion of the indicator in the analysis. An analysis was performed with the selected variables in CCHS. Each indicator was age-standardized, and both standardized and crude ratios of individuals engaging in selected indicator activities were calculated. The results were examined for reliability using the produced coefficient of variation values. The estimates for each risk indicators allowed for the identification of target population that may be at higher risk of developing cancer due to greater exposure to the risk factors. They also serve as useful predictors for areas of improvement in regions with a high prevalence, such as healthy living within the community, and a guide to implementing preventative measures, screening, or treatment plans that may have been lacking.
安大略癌症概况是一个面向公众的交互式仪表板,包含由安大略健康(安大略癌症护理)创建的人口水平的癌症统计数据。该工具包含由地方卫生综合网络(LHIN)和公共卫生单位(PHU)提供的有关癌症负担、癌症筛查措施和癌症风险因素的数据。它可用于卫生系统规划、衡量卫生系统绩效、监测干预措施的影响,并有助于确定新的研究领域。有9个新的可修改的癌症风险因素被提议纳入未来更新的仪表板。建议的风险因素包括:获得护理、主动交通、酗酒、戒酒、水果消费不足、蔬菜消费不足、久坐行为、二手烟暴露和阳光安全。我的实习包括两个主要目标:对提出的风险因素与癌症之间的关联进行文献综述,并使用2015年至2017年的CCHS数据确定安大略省已确定风险因素的暴露率。我进行了一项文献综述,以检查将每个提出的风险因素与癌症风险联系起来的现有证据,以确定在分析中纳入或排除该指标。对CCHS中选取的变量进行分析。每个指标都进行了年龄标准化,并计算了参与选定指标活动的个体的标准化比率和粗比率。使用产生的变异系数值检验结果的可靠性。每个风险指标的估计值可用于确定由于暴露于风险因素较多而可能患癌症风险较高的目标人群。它们还可以作为有用的预测指标,用于预测高患病率地区的改善领域,例如社区内的健康生活,以及实施可能缺乏的预防措施、筛查或治疗计划的指南。
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引用次数: 0
Current diesel engine exhaust exposure in the Ontario construction industry 目前柴油发动机废气暴露在安大略省建筑业
Pub Date : 2021-09-15 DOI: 10.33137/utjph.v2i2.37006
Stephanie Ziembicki, T. Kirkham, P. Demers, Cheryl E Peters, Melanie Gorman-Ng, H. Davies, T. Tenkate, S. Kalengé, Nicola Blagrove-Hall, Kate Jardine, V. Arrandale
Introduction: Diesel engine exhaust (DEE) is a known carcinogen and a common occupational exposure in Canada, particularly within construction. The use of diesel-powered equipment in the construction industry is widespread, but little is known about DEE exposures and occupational disease in this work setting. The objective of this study was to characterize and identify key determinants of DEE exposure at construction sites in Ontario. Methods: Diesel particulate matter (DPM) measurements were taken from workers employed on seven infrastructure construction worksites in Ontario. Full-shift personal air samples were collected from workers using a constant-flow pump and SKC aluminum cyclone with 37-mm quartz fibre filters in an open-faced cassette. Samples were analyzed for elemental carbon (EC), a surrogate of DEE exposure, following NIOSH method 5040. Exposures were compared to recommended health-based limits, including the Dutch Expert Committee on Occupational Safety (DECOS) limit (1.03µg/m3 respirable EC) and the Finnish Institute of Occupational Health (FIOH) recommendation (5µg/m3 respirable EC). A determinants of exposure model was constructed. Results: In total, 126 DPM samples were collected, ranging from <0.47-52.58µg/m3 with a geometric mean (GM) of 4.23µg/m3 (geometric standard deviation (GSD)=3.05). Overall, 44.8% of samples exceeded the FIOH limit, mostly within underground worksites (93.5%), and 88.8% exceeded the DECOS limit. Underground workers (GM=13.20µg/m3, GSD=1.83) had exposures approximately 4-times higher than below grade workers (GM=3.56µg/m3, GSD=1.94) and 9-times higher than aboveground workers (GM=1.49µg/m3, GSD=1.75). Work grade, enclosed cabs, and seasonality were identified as the major determinants of exposure. Conclusions: This study provides a better understanding of current DPM exposure in Canadian construction. Most exposures were above recommended health-based limits, signifying a need to further reduce DPM levels in construction. These results can inform a hazard reduction strategy including a new occupational exposure limit and targeted intervention/control measures to reduce DPM exposure and the burden of occupational cancer.
简介:柴油机废气(DEE)是一种已知的致癌物,也是加拿大常见的职业暴露,特别是在建筑行业。在建筑工业中广泛使用柴油动力设备,但对这种工作环境中的DEE暴露和职业病知之甚少。本研究的目的是表征和确定安大略省建筑工地DEE暴露的关键决定因素。方法:对安大略省七个基础设施建设工地的工人进行柴油颗粒物(DPM)测量。使用恒流泵和SKC铝旋流器收集工人的全班次个人空气样本,该旋流器带有37毫米石英纤维过滤器,位于开放式盒式中。根据NIOSH 5040方法分析样品中的元素碳(EC),这是DEE暴露的替代物。将暴露量与基于健康的建议限值进行比较,包括荷兰职业安全专家委员会(DECOS)限值(1.03µg/m3可吸入EC)和芬兰职业卫生研究所(FIOH)建议限值(5µg/m3可吸入EC)。建立了暴露决定因素模型。结果:共采集到DPM样品126份,范围<0.47 ~ 52.58µg/m3,几何平均值(GM)为4.23µg/m3(几何标准差(GSD)=3.05)。总体而言,44.8%的样品超过FIOH限值(93.5%),主要是地下工地,88.8%的样品超过DECOS限值。地下工人(GM=13.20µg/m3, GSD=1.83)的暴露量大约是地下工人(GM=3.56µg/m3, GSD=1.94)的4倍,是地上工人(GM=1.49µg/m3, GSD=1.75)的9倍。工作等级、封闭驾驶室和季节性被确定为暴露的主要决定因素。结论:本研究对加拿大建筑中DPM暴露的现状提供了更好的了解。大多数接触量高于建议的基于健康的限值,表明需要进一步降低建筑中的DPM水平。这些结果可以为减少危害战略提供信息,包括新的职业暴露限值和有针对性的干预/控制措施,以减少DPM暴露和职业癌症负担。
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引用次数: 0
The Effect of Back Pain on Health Care Utilization and Costs 背部疼痛对医疗保健利用和费用的影响
Pub Date : 2021-09-15 DOI: 10.33137/utjph.v2i2.37005
Jessica J. Wong, P. Côté, A. Tricco, T. Watson, L. Rosella
Introduction: We assessed the effect of self-reported back pain on health care utilization and costs in a population-based sample of Ontario adults. Methods: We conducted a population-based matched cohort study of Ontarian respondents aged ≥18 years of Canadian Community Health Survey (CCHS) from 2003-2012. CCHS data were individually linked to health administrative data to measure health care utilization and costs up to 2018. We propensity-score matched (hard-matched on sex) adults with self-reported back pain to those without back pain, accounting for sociodemographic, health-related, and behavioural factors. We evaluated back pain-specific and all-cause health care utilization and costs from healthcare payer perspective adjusted to 2018 Canadian dollars. Poisson and linear (log-transformed) models were used to assess healthcare utilization rates and costs.  Results: After propensity-score matching, we identified 36,806 pairs (21,054 for women, 15,752 for men) of CCHS respondents with and without back pain (mean age 51 years; SD=18). Compared to propensity-score matched adults without back pain, adults with back pain had two times the rate of back pain-specific visits (women: rate ratio [RR] 2.06, 95% CI 1.88-2.25; men: RR 2.32, 95% CI 2.04-2.64), 1.1 times the rate of all-cause physician visits (women: RR 1.12, 95% CI 1.09-1.16; men: RR 1.10, 95% CI 1.05-1.14), and 1.2 times the costs (women: 1.21, 95% CI 1.16-1.27; men: 1.16, 95% CI 1.09-1.23). Incremental annual per-person costs were higher in adults with back pain versus those without (women: $395, 95% CI $281-$509; men: $196, 95% CI $94-$300), corresponding to $532 million for women and $227 million CAD for men annually in Ontario. Conclusions: Adults with back pain had considerably higher health care utilization and costs compared to adults without back pain. These findings provide the most recent, comprehensive, and high-quality estimates of the health system burden of back pain to inform healthcare policy and decision-making. New strategies to reduce the substantial burden of back pain are warranted.
导言:我们评估了自我报告的背部疼痛对安大略省成年人的医疗保健利用和成本的影响。方法:我们对2003-2012年加拿大社区健康调查(CCHS)中年龄≥18岁的安大略省受访者进行了一项基于人群的匹配队列研究。CCHS数据单独与卫生行政数据相关联,以衡量截至2018年的卫生保健利用和成本。考虑到社会人口统计学、健康相关和行为因素,我们将自我报告背痛的成年人与无背痛的成年人进行了倾向评分匹配(性别硬匹配)。我们从医疗保健付款人的角度评估了背痛特异性和全因医疗保健的利用和成本,调整为2018年加元。使用泊松和线性(对数转换)模型来评估医疗保健利用率和成本。结果:在倾向得分匹配后,我们确定了36,806对(女性21054对,男性15752对)有或没有背痛的CCHS受访者(平均年龄51岁;SD = 18)。与倾向评分匹配的无背痛的成年人相比,患有背痛的成年人因背痛而就诊的比率是前者的两倍(女性:比率比[RR] 2.06, 95% CI 1.88-2.25;男性:RR 2.32, 95% CI 2.04-2.64),全因就诊率的1.1倍(女性:RR 1.12, 95% CI 1.09-1.16;男性:RR 1.10, 95% CI 1.05-1.14),是成本的1.2倍(女性:1.21,95% CI 1.16-1.27;男性:1.16,95% CI 1.09-1.23)。有背痛的成年人的年人均增量费用高于无背痛的成年人(女性:395美元,95% CI 281- 509美元;男性:$196,95% CI $94-$300),相当于安大略省女性每年$ 5.32亿加元,男性每年$ 2.27亿加元。结论:与没有背痛的成年人相比,有背痛的成年人有更高的医疗保健利用率和成本。这些发现提供了最新的、全面的、高质量的背部疼痛卫生系统负担估计,为卫生保健政策和决策提供信息。减轻背痛负担的新策略是必要的。
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引用次数: 0
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University of Toronto Journal of Public Health
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