Shift work continues to increase in frequency in industrial society and accounts for more than 20% of workers in modern society. Previous studies have reported that shift work is a representative environmental factor that disrupts circadian rhythm and is associated with various physical and mental problems, including sleep problems. In particular, problems with circadian rhythm are closely related to difficulties in emotional regulation that cause mood disorders. In this review, we reviewed previous studies on emotion dysregulation in shift workers and examined past studies on the neuroscience basis for these problems. If neurobiological research yields results on shift workers’ vulnerability to emotional and sleep problems, it would be possible to suggest ways to prevent the adverse mental effects of shift work.
{"title":"Emotional Dysregulation in Shift Workers","authors":"Yu Jin Lee","doi":"10.33069/cim.2023.0031","DOIUrl":"https://doi.org/10.33069/cim.2023.0031","url":null,"abstract":"Shift work continues to increase in frequency in industrial society and accounts for more than 20% of workers in modern society. Previous studies have reported that shift work is a representative environmental factor that disrupts circadian rhythm and is associated with various physical and mental problems, including sleep problems. In particular, problems with circadian rhythm are closely related to difficulties in emotional regulation that cause mood disorders. In this review, we reviewed previous studies on emotion dysregulation in shift workers and examined past studies on the neuroscience basis for these problems. If neurobiological research yields results on shift workers’ vulnerability to emotional and sleep problems, it would be possible to suggest ways to prevent the adverse mental effects of shift work.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139136250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In spaceflight operations, flight controllers manage technical aspects of spaceflight control and spacecraft systems. The flight control team is a group subjected to shift work. Acute and chronic exposure to shift work has been associated with circadian misalignment, sleep impairment, and a negative impact on cognitive performance. This study aims to review the effects of shift work on sleep, circadian rhythms, mood, and cognitive performance of flight controllers during real and simulated spaceflight operations. Shift work during low-Earth orbit spaceflight missions is associated with a reduction in alertness, motivation, processing speed, and working memory performance efficiency. Flight controllers also report excessive insomnia and insufficient total sleep time. The development of shift work sleep disorder may be present in up to 40% of workers, especially among night and evening shift workers. Mars operations and Mars-simulated missions are associated with an impairment of visual-motor performance, working memory efficiency, and reaction time. Between 50%–87% of controllers can synchronize their circadian rhythm to a Mars day (24.65 hours), although this adaptation is not reflected in improved neurobehavioral performance.
{"title":"Sleep Disruption, Fatigue, and Altered Neurobehavioral Performance Among Flight Controllers During Spaceflight Operations","authors":"Manuel Albornoz-Miranda, Gabriel Góngora-Jercic","doi":"10.33069/cim.2023.0025","DOIUrl":"https://doi.org/10.33069/cim.2023.0025","url":null,"abstract":"In spaceflight operations, flight controllers manage technical aspects of spaceflight control and spacecraft systems. The flight control team is a group subjected to shift work. Acute and chronic exposure to shift work has been associated with circadian misalignment, sleep impairment, and a negative impact on cognitive performance. This study aims to review the effects of shift work on sleep, circadian rhythms, mood, and cognitive performance of flight controllers during real and simulated spaceflight operations. Shift work during low-Earth orbit spaceflight missions is associated with a reduction in alertness, motivation, processing speed, and working memory performance efficiency. Flight controllers also report excessive insomnia and insufficient total sleep time. The development of shift work sleep disorder may be present in up to 40% of workers, especially among night and evening shift workers. Mars operations and Mars-simulated missions are associated with an impairment of visual-motor performance, working memory efficiency, and reaction time. Between 50%–87% of controllers can synchronize their circadian rhythm to a Mars day (24.65 hours), although this adaptation is not reflected in improved neurobehavioral performance.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":" 688","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139136570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Alexander Changestu, Ery Hermawati, Agustina Arundina Triharja Tejoyuwono
This cross-sectional study aimed to identify the correlation between chronotype and body mass index (BMI) in medical students, mediated by energy intake, and to explore eating habits. There were 46 participants who completed Morningness-Eveningness Questionnaire and Chrononutrition- Profile Questionnaire in the Indonesia version and a 3 days of 24-hour food record. Participants’ weight and height were measured by microtoise and digital body weight scale. Additionally, univariate and correlation analyses were conducted to identify the correlation of the variables. The study found no significant difference in the correlation between chronotype preference and BMI, chronotype preference and energy intake, and BMI and energy intake. Medical students had a habit of eating breakfast, even skipping breakfast, having dinner later, consuming the highest energy at lunchtime, and consuming high-calorie, high-fat, and high-sugar foods at night. The study revealed no significant correlation between chronotype, eating habits, and BMI. However, the eveningness medical students have bad eating habits.
{"title":"Chronotype, Eating Habits, and Body Mass Index in First-Year Undergraduate Medical Program Students","authors":"Daniel Alexander Changestu, Ery Hermawati, Agustina Arundina Triharja Tejoyuwono","doi":"10.33069/cim.2023.0029","DOIUrl":"https://doi.org/10.33069/cim.2023.0029","url":null,"abstract":"This cross-sectional study aimed to identify the correlation between chronotype and body mass index (BMI) in medical students, mediated by energy intake, and to explore eating habits. There were 46 participants who completed Morningness-Eveningness Questionnaire and Chrononutrition- Profile Questionnaire in the Indonesia version and a 3 days of 24-hour food record. Participants’ weight and height were measured by microtoise and digital body weight scale. Additionally, univariate and correlation analyses were conducted to identify the correlation of the variables. The study found no significant difference in the correlation between chronotype preference and BMI, chronotype preference and energy intake, and BMI and energy intake. Medical students had a habit of eating breakfast, even skipping breakfast, having dinner later, consuming the highest energy at lunchtime, and consuming high-calorie, high-fat, and high-sugar foods at night. The study revealed no significant correlation between chronotype, eating habits, and BMI. However, the eveningness medical students have bad eating habits.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"75 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139132160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Young-Min Park, So-Jin Lee, Jin-Seong Lee, Kyoung-Sae Na, Seungche Kang, Bun-Hee Lee, Ho-Kyoung Yoon, Eui-Joong Kim
Objective: Melatonin, both immediate and prolonged-release formulations, has been explored as an adjunctive treatment for insomnia, with prolonged-release melatonin demonstrating enhanced efficacy compared to its immediate-release counterpart. However, there remains a gap in understanding its effectiveness specifically in individuals with treatment-resistant insomnia, who continue to experience sleep difficulties despite using traditional hypnotic medications.Methods: An 8-week prospective, open-label, observational study was conducted on 115 patients aged 55 years or older with insomnia several years ago. This is a post-hoc analysis, which was performed on 63 out of 115 patients who were already taking hypnotics and still reported symptoms of insomnia. Per protocol (n=40) and last observation carried forward (LOCF) approaches (n=63) were used, assessing changes in sleep indicators after administering 2 mg of prolonged-release melatonin. Psychometric scales including Pittsburgh Sleep Quality Index (PSQI) and WHO-5 Well-Being Index were used for evaluation at baseline, week 4, and week 8.Results: The per protocol and LOCF analysis revealed substantial improvements in sleep latency, total sleep time, sleep efficiency, and total PSQI scores after 8 weeks of prolonged-release melatonin treatment. The LOCF analysis also revealed WHO-5 Well-Being Index significantly increased. Compared to prolonged-release melatonin monotherapy group with combination therapy group (adding prolonged-release melatonin to previous hypnotics) at baseline, 4 weeks, and 8 weeks after treatment, most variables did not differ between two groups in the per protocol and LOCF analysis. However, only WHO-5 Well-Being Index was higher in monotherapy group than in combination group at 4 weeks and 8 weeks after prolonged-release melatonin treatment in the per protocol analysis.Conclusion: Prolonged-release melatonin demonstrated notable efficacy in ameliorating sleep latency, duration, efficiency, and overall quality in treatment-resistant insomnia patients. The study highlights its potential as a treatment avenue for this challenging cohort, prompting further exploration into its benefits, particularly in improving overall well-being, and advocating for expanded research in this domain.
{"title":"Efficacy of Prolonged-Release Melatonin Administration in Elderly Patients With Treatment Resistant Insomnia: A Post-Hoc Analysis","authors":"Young-Min Park, So-Jin Lee, Jin-Seong Lee, Kyoung-Sae Na, Seungche Kang, Bun-Hee Lee, Ho-Kyoung Yoon, Eui-Joong Kim","doi":"10.33069/cim.2023.0030","DOIUrl":"https://doi.org/10.33069/cim.2023.0030","url":null,"abstract":"Objective: Melatonin, both immediate and prolonged-release formulations, has been explored as an adjunctive treatment for insomnia, with prolonged-release melatonin demonstrating enhanced efficacy compared to its immediate-release counterpart. However, there remains a gap in understanding its effectiveness specifically in individuals with treatment-resistant insomnia, who continue to experience sleep difficulties despite using traditional hypnotic medications.Methods: An 8-week prospective, open-label, observational study was conducted on 115 patients aged 55 years or older with insomnia several years ago. This is a post-hoc analysis, which was performed on 63 out of 115 patients who were already taking hypnotics and still reported symptoms of insomnia. Per protocol (n=40) and last observation carried forward (LOCF) approaches (n=63) were used, assessing changes in sleep indicators after administering 2 mg of prolonged-release melatonin. Psychometric scales including Pittsburgh Sleep Quality Index (PSQI) and WHO-5 Well-Being Index were used for evaluation at baseline, week 4, and week 8.Results: The per protocol and LOCF analysis revealed substantial improvements in sleep latency, total sleep time, sleep efficiency, and total PSQI scores after 8 weeks of prolonged-release melatonin treatment. The LOCF analysis also revealed WHO-5 Well-Being Index significantly increased. Compared to prolonged-release melatonin monotherapy group with combination therapy group (adding prolonged-release melatonin to previous hypnotics) at baseline, 4 weeks, and 8 weeks after treatment, most variables did not differ between two groups in the per protocol and LOCF analysis. However, only WHO-5 Well-Being Index was higher in monotherapy group than in combination group at 4 weeks and 8 weeks after prolonged-release melatonin treatment in the per protocol analysis.Conclusion: Prolonged-release melatonin demonstrated notable efficacy in ameliorating sleep latency, duration, efficiency, and overall quality in treatment-resistant insomnia patients. The study highlights its potential as a treatment avenue for this challenging cohort, prompting further exploration into its benefits, particularly in improving overall well-being, and advocating for expanded research in this domain.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"121 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139133965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sleeping Pills and Increased Mortality and Suicide","authors":"Heon-Jeong Lee","doi":"10.33069/cim.2023.0032","DOIUrl":"https://doi.org/10.33069/cim.2023.0032","url":null,"abstract":"","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139132573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: During the past decades, several studies have explored individuals’ differences and their impact on scholarly achievement. The effect of circadian preference and personality on academic performance has been studied in different countries. However, studies have yet to analyze these variables in the Moroccan context (North West Africa) and test whether academic performance relates to circadian types and personality traits. This study aimed to investigate the relationship between those variables in young active students.Methods: This study included 167 Moroccan active students (age=16.34 years; SD=1.2). The personality trait was measured with Big Five Questionnaire for Children (BFQ-C). We also assessed the circadian typology by using Morningness–Eveningness Questionnaire (MEQ). School grades were used to calculate academic success (grade point average [GPA]). We investigated the relationships between all the parameters.Results: This study indicates a significant difference in Big Five factors between athlete groups of chronotype. GPA is significantly related positively to MEQ score and openness but negatively to neuroticism. However, no correlation was observed with the other significant five factors.Conclusion: Professionals must consider circadian preferences and personality traits when looking to facilitate students’ scholarly achievement.
{"title":"Effect of Circadian Preferences and Personality Traits on Academic Achievement in Active Students","authors":"A. El-Jaziz, S. Lotfi","doi":"10.33069/cim.2023.0008","DOIUrl":"https://doi.org/10.33069/cim.2023.0008","url":null,"abstract":"Objective: During the past decades, several studies have explored individuals’ differences and their impact on scholarly achievement. The effect of circadian preference and personality on academic performance has been studied in different countries. However, studies have yet to analyze these variables in the Moroccan context (North West Africa) and test whether academic performance relates to circadian types and personality traits. This study aimed to investigate the relationship between those variables in young active students.Methods: This study included 167 Moroccan active students (age=16.34 years; SD=1.2). The personality trait was measured with Big Five Questionnaire for Children (BFQ-C). We also assessed the circadian typology by using Morningness–Eveningness Questionnaire (MEQ). School grades were used to calculate academic success (grade point average [GPA]). We investigated the relationships between all the parameters.Results: This study indicates a significant difference in Big Five factors between athlete groups of chronotype. GPA is significantly related positively to MEQ score and openness but negatively to neuroticism. However, no correlation was observed with the other significant five factors.Conclusion: Professionals must consider circadian preferences and personality traits when looking to facilitate students’ scholarly achievement.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122370496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We present a 24-year-old male patient with a history of episod-ic migraine without aura since age 12. He was initially medicated with topiramate, but due to adverse effects, a switch was made to propranolol with a gradual increase to 40 mg twice a day. Despite an improvement in the frequency, duration, and intensity of the headache crisis, 2 weeks after starting this therapy, the patient started having nocturnal episodes, every week, characterized by wandering around the house and carrying out purposeless ev-eryday tasks, with minimal interaction, lasting several minutes. The patient reported occasional soliloquies, but without a previous history of somnambulism or other sleep parasomnias, par-ticularly in childhood, but with a positive family history of sleepwalking (brother). A diagnosis of somnambulism induced by propranolol was made. The patient stopped gradually the propranolol and started amitriptyline until 25 mg/day, with the resolution of the sleepwalking and good control of his migraine. In this report, the patient had no history of somnambulism, al-though positive familiar history. He experienced episodes of sleepwalking 15 days after starting propranolol until 40 mg bid. The symptoms completely disappeared after the withdrawal of propranolol. In the literature, there are 5 more cases of somnambulism related to propranolol [1-3]. All patients were female (age range: 24–61 years old), with propranolol doses between 20–120 mg/day. In one of them, propranolol was added with another drug (olanzapine). In 3 of the patients, there was a history of somnambulism. The onset of sleepwalking ranged from 1–33 days after
{"title":"Propanolol-Induced Somnambulism: An Ignored Adverse Effect?","authors":"Gonçalo Cabral, Cláudia Borbinha, S. Calado","doi":"10.33069/cim.2023.0012","DOIUrl":"https://doi.org/10.33069/cim.2023.0012","url":null,"abstract":"We present a 24-year-old male patient with a history of episod-ic migraine without aura since age 12. He was initially medicated with topiramate, but due to adverse effects, a switch was made to propranolol with a gradual increase to 40 mg twice a day. Despite an improvement in the frequency, duration, and intensity of the headache crisis, 2 weeks after starting this therapy, the patient started having nocturnal episodes, every week, characterized by wandering around the house and carrying out purposeless ev-eryday tasks, with minimal interaction, lasting several minutes. The patient reported occasional soliloquies, but without a previous history of somnambulism or other sleep parasomnias, par-ticularly in childhood, but with a positive family history of sleepwalking (brother). A diagnosis of somnambulism induced by propranolol was made. The patient stopped gradually the propranolol and started amitriptyline until 25 mg/day, with the resolution of the sleepwalking and good control of his migraine. In this report, the patient had no history of somnambulism, al-though positive familiar history. He experienced episodes of sleepwalking 15 days after starting propranolol until 40 mg bid. The symptoms completely disappeared after the withdrawal of propranolol. In the literature, there are 5 more cases of somnambulism related to propranolol [1-3]. All patients were female (age range: 24–61 years old), with propranolol doses between 20–120 mg/day. In one of them, propranolol was added with another drug (olanzapine). In 3 of the patients, there was a history of somnambulism. The onset of sleepwalking ranged from 1–33 days after","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132102034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This review paper explores the relationship between circadian rhythm and postpartum depression (PPD). Postpartum depression is a prevalent and debilitating mood disorder that affects a significant number of women after childbirth. Emerging evidence suggests that disruptions in circadian rhythm may contribute to the development of PPD. This paper provides an overview of the current understanding of circadian rhythm disturbances in the postpartum period, their potential impact on PPD, and the underlying mechanisms involved. Additionally, therapeutic approaches targeting circadian disruptions in the prevention and treatment of PPD are discussed. Further research in this field has the potential to provide novel insights and interventions for the management of PPD.
{"title":"Exploring the Relationship Between Circadian Rhythm Shifts and Postpartum Depression","authors":"Jihye Yeom, Heon-Jeong Lee","doi":"10.33069/cim.2023.0014","DOIUrl":"https://doi.org/10.33069/cim.2023.0014","url":null,"abstract":"This review paper explores the relationship between circadian rhythm and postpartum depression (PPD). Postpartum depression is a prevalent and debilitating mood disorder that affects a significant number of women after childbirth. Emerging evidence suggests that disruptions in circadian rhythm may contribute to the development of PPD. This paper provides an overview of the current understanding of circadian rhythm disturbances in the postpartum period, their potential impact on PPD, and the underlying mechanisms involved. Additionally, therapeutic approaches targeting circadian disruptions in the prevention and treatment of PPD are discussed. Further research in this field has the potential to provide novel insights and interventions for the management of PPD.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122531209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The discrepancy between self-reported subjective sleep time and objective sleep time varies from person to person, and the mechanism that can explain this discrepancy is unclear. This study aimed to investigate the difference in the spectral power of sleep electroencephalography (EEG) according to the estimation of total sleep time (TST).Methods: Of the 4,080 participants in the Sleep Heart Health Study, 2,363 participants with complete data from polysomnography, morning sleep survey, and spectral power of sleep EEG were included in the analysis. The participants were classified as normo-estimators (estimation of TST <±60 min), under-estimators (underestimation of TST ≤60 min), or over-estimators (overestimation of TST ≥60 min). A fast Fourier transformation was used to calculate the EEG power spectrum for total sleep duration within contiguous 30-s epochs of sleep. The sleep EEG spectral power was compared among the groups after adjusting for potential confounding factors, such as age, sex, proportion of participants with insomnia, apnea-hypopnea index, and TST.Results: Of the 2,363 participants, 1,507 (63.8%), 412 (17.4%), and 444 (18.8%) were assigned to the normo-, under-, and over-estimator groups, respectively. The power spectra during total sleep differed significantly among the groups in the delta (p=0.008) and theta bands (p=0.017) after controlling for potential confounders.Conclusion: Higher delta and theta powers were found in the under-estimators than in the over-estimators. This study suggests that differences exist in the microstructures of polysomnography-derived sleep EEG between these two groups. This study suggests that differences exist in the microstructures of polysomnography-derived sleep EEG based on differences in sleep time estimation.
{"title":"The Difference in Spectral Power Density in Sleep Electroencephalography According to the Estimation of Total Sleep Time","authors":"Jun-Mu Heo, Seo-Eun Cho, Seungche Kang","doi":"10.33069/cim.2023.0010","DOIUrl":"https://doi.org/10.33069/cim.2023.0010","url":null,"abstract":"Objective: The discrepancy between self-reported subjective sleep time and objective sleep time varies from person to person, and the mechanism that can explain this discrepancy is unclear. This study aimed to investigate the difference in the spectral power of sleep electroencephalography (EEG) according to the estimation of total sleep time (TST).Methods: Of the 4,080 participants in the Sleep Heart Health Study, 2,363 participants with complete data from polysomnography, morning sleep survey, and spectral power of sleep EEG were included in the analysis. The participants were classified as normo-estimators (estimation of TST <±60 min), under-estimators (underestimation of TST ≤60 min), or over-estimators (overestimation of TST ≥60 min). A fast Fourier transformation was used to calculate the EEG power spectrum for total sleep duration within contiguous 30-s epochs of sleep. The sleep EEG spectral power was compared among the groups after adjusting for potential confounding factors, such as age, sex, proportion of participants with insomnia, apnea-hypopnea index, and TST.Results: Of the 2,363 participants, 1,507 (63.8%), 412 (17.4%), and 444 (18.8%) were assigned to the normo-, under-, and over-estimator groups, respectively. The power spectra during total sleep differed significantly among the groups in the delta (p=0.008) and theta bands (p=0.017) after controlling for potential confounders.Conclusion: Higher delta and theta powers were found in the under-estimators than in the over-estimators. This study suggests that differences exist in the microstructures of polysomnography-derived sleep EEG between these two groups. This study suggests that differences exist in the microstructures of polysomnography-derived sleep EEG based on differences in sleep time estimation.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129953836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yunjung Choi, Doo-Heum Park, S. Ryu, J. Ha, H. Jeon
Objective: This study aimed to examine the association between insomnia symptoms, sub-symptoms of panic disorder, and depressive symptoms in patients with panic disorder.Methods: A retrospective cross-sectional study was conducted with 192 patients diagnosed with panic disorder. Data on panic disorder severity, anxiety sensitivity, agoraphobia, insomnia severity, and depressive symptoms were collected using psychological instruments. Correlation analysis and logistic regression were employed to analyze the relationships between the variables.Results: Patients with panic disorder accompanied by significant depressive symptoms had a higher prevalence of insomnia, younger age, and more severe panic symptoms. Logistic regression analysis revealed an independent association between insomnia symptoms and the presence of depressive symptoms in panic disorder patients. Specific panic disorder sub-symptoms, such as fear of publicly observable anxiety reactions and fear of cognitive dyscontrol, exhibited stronger associations with depressive symptoms than overall panic severity.Conclusion: The findings suggest a significant association between insomnia, specific panic disorder sub-symptoms, and depressive symptoms in patients with panic disorder. Addressing insomnia and cognitive symptoms may be crucial in managing panic disorder and preventing depressive symptoms. Psychological interventions, particularly cognitive behavioral therapy, targeted at these factors could improve outcomes for panic disorder patients.
{"title":"Insomnia Symptom Independently Predict Depression in the Patients With Panic Disorder","authors":"Yunjung Choi, Doo-Heum Park, S. Ryu, J. Ha, H. Jeon","doi":"10.33069/cim.2023.0011","DOIUrl":"https://doi.org/10.33069/cim.2023.0011","url":null,"abstract":"Objective: This study aimed to examine the association between insomnia symptoms, sub-symptoms of panic disorder, and depressive symptoms in patients with panic disorder.Methods: A retrospective cross-sectional study was conducted with 192 patients diagnosed with panic disorder. Data on panic disorder severity, anxiety sensitivity, agoraphobia, insomnia severity, and depressive symptoms were collected using psychological instruments. Correlation analysis and logistic regression were employed to analyze the relationships between the variables.Results: Patients with panic disorder accompanied by significant depressive symptoms had a higher prevalence of insomnia, younger age, and more severe panic symptoms. Logistic regression analysis revealed an independent association between insomnia symptoms and the presence of depressive symptoms in panic disorder patients. Specific panic disorder sub-symptoms, such as fear of publicly observable anxiety reactions and fear of cognitive dyscontrol, exhibited stronger associations with depressive symptoms than overall panic severity.Conclusion: The findings suggest a significant association between insomnia, specific panic disorder sub-symptoms, and depressive symptoms in patients with panic disorder. Addressing insomnia and cognitive symptoms may be crucial in managing panic disorder and preventing depressive symptoms. Psychological interventions, particularly cognitive behavioral therapy, targeted at these factors could improve outcomes for panic disorder patients.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126292877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：