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Knowledge, Attitude and Practices among Undergraduate Medical Students Regarding Surgical Correction of Refractive Errors; a Cross-sectional Study 医大学生屈光不正手术矫正知识、态度与实践横断面研究
Pub Date : 2022-06-30 DOI: 10.9734/or/2022/v16i430239
Syedah Kanza Batool, Rabisa Batool, Kanwal Jamal, Muhammad Waqaruddin Sheroze, Muhammad Adil Ramzan, Syeda Afia Siddiqui
Aim: This study was aimed to assess the knowledge, attitude and practices regarding refractive error correction surgeries among undergraduate medical students. Study Design: In this study cross-sectional study design was used. Duration and Place of Study: The study was conducted amongst the undergraduate MBBS students studying at Dow Medical College, Karachi. The duration of study was seven months (August, 2019 till February, 2020). Methods: A sample size of 189 was calculated for the study with confidence level 95% and confidence limit 5%. Data was collected through a validated self-administered questionnaire which was divided in five subsections used to gain information regarding participant’s demographics, knowledge, attitude and practices regarding refractive error surgeries. Data was analyzed using IBM SPSS V.22. Results: In our study 189 students with a mean age of 21±1.8 years were included. Among the participants 112 (59.3%) had refractive errors. Glasses were used by majority 76 (67.9%) of participants for visual correction. Use of refractive error correction methods at all times was reported by 72 (66.7%) participants. Majority of respondents 142 (75.5%) had heard about surgery being used for correction of refractive errors. A large number of students 117 (66%) refused for surgery and fear of the outcomes was one of the reason for this refusal. Conclusion: We found that majority of the participants were aware about refractive error correction surgeries yet most of them showed unwillingness for these procedures. This negative attitude must be changed to positive in order to enhance the practice for these procedures.
目的:了解医学生对屈光不正手术的认知、态度和行为。研究设计:本研究采用横断面研究设计。研究时间和地点:本研究在卡拉奇陶氏医学院的MBBS本科生中进行。学习时间为7个月(2019年8月至2020年2月)。方法:本研究计算样本量189人,置信水平95%,置信限5%。数据是通过一份有效的自我管理问卷收集的,该问卷分为五个部分,用于获取参与者的人口统计信息,关于屈光不正手术的知识,态度和实践。数据分析采用IBM SPSS V.22。结果:本研究纳入189名学生,平均年龄21±1.8岁。参与者中有112人(59.3%)有屈光不正。76名(67.9%)的参与者使用眼镜进行视力矫正。72名(66.7%)参与者报告在任何时候都使用屈光不正矫正方法。大多数受访者(75.5%)听说过使用手术矫正屈光不正。大量的117名(66%)学生拒绝手术,对结果的恐惧是他们拒绝的原因之一。结论:我们发现大多数参与者都知道屈光不正手术,但大多数人不愿意接受这些手术。这种消极的态度必须转变为积极的态度,以加强对这些程序的实践。
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引用次数: 0
Efficacy Analysis of Corneal Photo-vitrification (CPV) for Improved Vision of Age-related Macular Degeneration (AMD) Eyes 角膜光玻璃化术(CPV)改善老年性黄斑变性(AMD)眼视力的疗效分析
Pub Date : 2022-06-21 DOI: 10.9734/or/2022/v16i330238
Jui-Teng Lin, Michael J. Berry
Purpose: To analyze the safety and efficacy of corneal photovitrification (CPV) for improved visions of age-related macular degeneration (AMD) eyes. Study Design: Using CPV for improved visions of AMD eyes. Place and Duration of Study: New Taipei City, Taiwan, and Austin, TX, USA; between April, 2022 and June, 2022. Methodology: The CPV efficacy is calculated based on the rate equation given by dM/dt=-k(t) M(t), where M(t) is the PCV-treated corneal stroma; and k(t) is the rate coefficient given by an Arrhenius formula, k(t) = A0 exp[−Ea/(RT(t,z)], where t and z are the laser irradiation time and depth of the cornea stroma; Ea  is the activation energy and R is the gas constant. The temperature spatial and temporal profiles are given by the numerical solutions of a heat diffusion equation with a volume heating source. Various effective depths including the tissue damage depth, temperature penetration depth and conversion depth, governed by the tissue absorption coefficient, light intensity and dose (or irradiation time), and the related threshold values, are introduced in replacing the conventional penetration depth based on a Beer's law. Results: The suggested protocol for CPV treatments include: a diode laser at about 2 µm wavelength (with absorption coefficient about 100 cm-1). The laser dose is about 25 J/cm2/spot and irradiation time of 150 ms. Conclusion: The efficacy of CPV may be predicted/calculated by our modeling based on rate equation and the corneal stroma temperature rise due to laser heating. The preferred retinal locus (PRL) movement observed post-CPV is caused mainly by neuroadaptation.
目的:分析角膜光玻璃化术(CPV)改善老年性黄斑变性(AMD)眼视力的安全性和有效性。研究设计:使用CPV改善AMD眼视力。学习地点及时间:台湾新北市及美国德州奥斯汀;2022年4月至2022年6月。方法:CPV疗效根据dM/dt=-k(t) M(t)给出的率方程计算,其中M(t)为pcv处理的角膜基质;k(t)为Arrhenius公式给出的速率系数,k(t) = A0 exp[−Ea/(RT(t,z)],其中t和z为激光照射角膜基质的时间和深度;Ea是活化能,R是气体常数。用带体积热源的热扩散方程的数值解给出了温度的时空分布。根据比尔定律,引入各种有效深度,包括组织损伤深度、温度穿透深度和转化深度,这些有效深度由组织吸收系数、光强和剂量(或照射时间)以及相关阈值决定,以取代传统的穿透深度。结果:建议的CPV治疗方案包括:波长约为2µm的二极管激光器(吸收系数约为100 cm-1)。激光剂量约为25j /cm2/光斑,照射时间为150ms。结论:基于速率方程和激光加热后角膜间质温升的模型可以预测/计算CPV的疗效。cpv后视网膜首选位点(PRL)运动主要由神经适应引起。
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引用次数: 2
Ethambutol Effect on Retinal and Optic Nerve Structural Changes in Toxic Optic Neuropathy Case: A Literature Review 乙胺丁醇对中毒性视神经病变视网膜和视神经结构改变的影响:文献综述
Pub Date : 2022-06-16 DOI: 10.9734/or/2022/v16i330237
Itzar Chaidir Islam, B. Umar, Rahmawati Minhajat, A. Bukhari, D. K. Sari, C. Kaelan
Introduction: Ethambutol (EMB) is one of the first-line antituberculosis drugs that reported to cause toxic effects on the eye structure. This study aims to elucidate the histological mechanism of retinal and optic nerve damage in toxic optic neuropathy cases. Reference Sources: The literature search was conducted in the PUBMED and MEDLINE databases using the latest publication of the 2012-2022 series. Studies Selection: The observational and randomized controlled trial studies analyzing the effect of ethambutol on retinal nerve fiber layer, retinal ganglion layer, inner cell plexiform layer thickness, optic nerve tissue, best-corrected visual acuity (BCVA), color perception, visual evoked response, and patients' visual field were included. Data Extraction Method: Articles that met the inclusion criteria underwent a specific evaluation, whereby the main focus was the ethambutol on retinal and optic nerve tissue. Results: The results showed that ethambutol affects the thinning of the Retinal Nerve Fiber Layer (RNFL), decreasing the amount of Ganglion Cells and changing the optic nerve's histological function by damaging the mitochondria and axonal fiber. Conclusion: It was concluded that ethambutol has adverse effects on retinal and optic nerve tissue due to several mechanisms and significantly affects the patient's visual outcome.
乙胺丁醇(ethambutool, EMB)是一线抗结核药物之一,据报道对眼睛结构有毒性作用。本研究旨在阐明中毒性视神经病变视网膜和视神经损伤的组织学机制。参考来源:文献检索在PUBMED和MEDLINE数据库中进行,使用2012-2022系列的最新出版物。研究选择:纳入分析乙胺丁醇对视网膜神经纤维层、视网膜神经节层、内细胞丛状层厚度、视神经组织、最佳矫正视力(BCVA)、色觉、视觉诱发反应、患者视野影响的观察性和随机对照试验研究。数据提取方法:对符合纳入标准的文章进行具体评估,主要关注乙胺丁醇对视网膜和视神经组织的影响。结果:乙胺丁醇通过损伤线粒体和轴突纤维,影响视网膜神经纤维层(RNFL)变薄,神经节细胞数量减少,改变视神经的组织学功能。结论:乙胺丁醇通过多种机制对视网膜和视神经组织产生不良反应,显著影响患者的视力。
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引用次数: 0
Evaluation of Visual Acuity among Commercial Motorcyclists (Okada Riders) in the Main Campus of Abia State University Uturu Abia State Nigeria 尼日利亚Uturu Abia州立大学主校区商业摩托车手(Okada骑手)的视力评估
Pub Date : 2022-06-08 DOI: 10.9734/or/2022/v16i330236
C. D. Ubani, A. Amah, C. Ofoegbu, Chijioke, I. Ugboaja
The visual ability of road users is fundamental to traffic safety. Despite the high burden of traffic crashes and associated mortality in low-income countries such as Nigeria, evidence for an association between vision function and traffic safety outcomes is scarce. Therefore, the aim of this work was to evaluate the visual acuity of commercial motorcyclists operating within the main campus of Abia State University, Uturu. Two hundred operators who had been on the job for at least one year constituted the test population, while staff and students of Abia State University, Uturu, who were sex and aged-matched and who are not commercial motor cyclists constituted the control group. Data were obtained with the aid of a structured questionnaire and clinical examinations were carried out by standard procedures. Results showed that Snellen’s fraction which is a indicator of visual acuity for the left eye of control and test groups  was recorded as 0.98+- 0.30 and 0.88+- 0.35 respectively and for the right eyes 0.99+- 0.10 and 0.87+- 0.50 respectively. Only 38% of test group had normal visual acuity of 6/6 compared to 73% of control. Visual acuity correlated negatively with age for the left (r = - 0.712) and right (r = - 0.740) eyes as well as with length of service for left (r = -0.623 and right (r = - 0.632) eyes of motorcyclist operators. In conclusion, visual acuity was inversely proportional to age and length of service.   
道路使用者的视觉能力对交通安全至关重要。尽管在尼日利亚等低收入国家,交通事故和相关死亡率负担很高,但视力功能与交通安全结果之间存在关联的证据很少。因此,这项工作的目的是评估在Uturu阿比亚州立大学主校区内运营的商业摩托车手的视力。200名工作至少一年的操作员构成了测试人群,而性别和年龄匹配且非商业摩托车手的阿比亚州立大学的工作人员和学生构成了对照组。通过结构化问卷调查获得数据,并按标准程序进行临床检查。结果显示,对照组和试验组左眼视力指标Snellen分数分别为0.98+- 0.30和0.88+- 0.35,右眼视力指标Snellen分数分别为0.99+- 0.10和0.87+- 0.50。试验组只有38%的患者视力达到6/6,而对照组为73%。摩托车驾驶员的左眼(r = - 0.712)和右眼(r = - 0.740)视力与年龄呈负相关,左眼(r = -0.623)和右眼(r = - 0.632)视力与工作年限呈负相关。总之,视力与年龄和服务年限成反比。
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引用次数: 0
Oculo-visual Assessment of Children and Adolescents with Special Needs in Selected Schools within IMO State, Nigeria 尼日利亚国际海事组织州选定学校中有特殊需要的儿童和青少年的视觉评估
Pub Date : 2022-06-08 DOI: 10.9734/or/2022/v16i330235
Chioma Lilian Owunna, Chigozie John Ekenze, Ifeoma Kate Okorie, A. U. Akujobi, J. Obioma-Elemba, Oyinyechi Lilian Umunnakwe, M. Ramyil, T. Ogundeko
Aim: This was a cross-sectional study conducted to assess the oculo-visual status of children with special needs in three selected special schools in Imo State, Nigeria. Children with special needs are at a higher risk of visual impairment as compared to normal population. Interestingly, majority of the ocular disorders are treatable. Methodology: The study was conducted on children ages 5-25years (mean 12.0 ± 3.2 years) and detailed ocular examination on 296 children using standard examination techniques was recorded. Results: Results revealed that oculo-visual disorders were seen in 196 (66.2%) children. Oculo-visual disorders were found in 75.5% of children with hearing impairment, 83.3% in children with cerebral palsy, 75% in children with autism, 85.7% in children with Down syndrome, 38.6% in children with speech disability, and 64% in children who are deaf and dumb. The most common ocular disorders seen in these children were refractive errors (30.5%), strabismus (12.7%), amblyopia (8.9%) and cataract (7.7%). Children requiring further evaluation were referred to base hospitals in Imo State, Nigeria. Conclusion: Oculo-visual problem is highly prevalent among children with special needs in Imo State, most commonly, the problems were refractive errors, strabismus, amblyopia, cataract and cornea disorders. The prevalence was predominant among the female teenagers (15-19years). Government and stakeholders in the health care and humanitarian sectors should place more priority on the ocular-health status of children with special needs.
目的:这是一项横断面研究,旨在评估尼日利亚伊莫州选定的三所特殊学校中有特殊需要的儿童的视力状况。与正常人群相比,有特殊需要的儿童视力受损的风险更高。有趣的是,大多数眼部疾病是可以治疗的。方法:研究对象为5-25岁儿童(平均12.0±3.2岁),采用标准检查技术对296名儿童进行详细的眼部检查。结果:196例(66.2%)患儿出现视力障碍。听力障碍儿童中视力障碍发生率为75.5%,脑瘫儿童中为83.3%,自闭症儿童中为75%,唐氏综合征儿童中为85.7%,语言障碍儿童中为38.6%,聋哑儿童中为64%。这些儿童中最常见的眼部疾病是屈光不正(30.5%)、斜视(12.7%)、弱视(8.9%)和白内障(7.7%)。需要进一步评估的儿童被转介到尼日利亚伊莫州的基地医院。结论:在伊莫州有特殊需要的儿童中,视力问题非常普遍,最常见的问题是屈光不正、斜视、弱视、白内障和角膜疾病。以15 ~ 19岁女性青少年为主。政府和保健和人道主义部门的利益攸关方应更加重视有特殊需要的儿童的眼健康状况。
{"title":"Oculo-visual Assessment of Children and Adolescents with Special Needs in Selected Schools within IMO State, Nigeria","authors":"Chioma Lilian Owunna, Chigozie John Ekenze, Ifeoma Kate Okorie, A. U. Akujobi, J. Obioma-Elemba, Oyinyechi Lilian Umunnakwe, M. Ramyil, T. Ogundeko","doi":"10.9734/or/2022/v16i330235","DOIUrl":"https://doi.org/10.9734/or/2022/v16i330235","url":null,"abstract":"Aim: This was a cross-sectional study conducted to assess the oculo-visual status of children with special needs in three selected special schools in Imo State, Nigeria. \u0000Children with special needs are at a higher risk of visual impairment as compared to normal population. Interestingly, majority of the ocular disorders are treatable. \u0000Methodology: The study was conducted on children ages 5-25years (mean 12.0 ± 3.2 years) and detailed ocular examination on 296 children using standard examination techniques was recorded. Results: Results revealed that oculo-visual disorders were seen in 196 (66.2%) children. Oculo-visual disorders were found in 75.5% of children with hearing impairment, 83.3% in children with cerebral palsy, 75% in children with autism, 85.7% in children with Down syndrome, 38.6% in children with speech disability, and 64% in children who are deaf and dumb. The most common ocular disorders seen in these children were refractive errors (30.5%), strabismus (12.7%), amblyopia (8.9%) and cataract (7.7%). Children requiring further evaluation were referred to base hospitals in Imo State, Nigeria. \u0000Conclusion: Oculo-visual problem is highly prevalent among children with special needs in Imo State, most commonly, the problems were refractive errors, strabismus, amblyopia, cataract and cornea disorders. The prevalence was predominant among the female teenagers (15-19years). Government and stakeholders in the health care and humanitarian sectors should place more priority on the ocular-health status of children with special needs.","PeriodicalId":287685,"journal":{"name":"Ophthalmology Research: An International Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128719179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Central Retinal Vein Occlusion Secondary to Paroxysmal Nocturnal Hemoglobinuria 继发于阵发性夜间血红蛋白尿的视网膜中央静脉阻塞
Pub Date : 2022-05-27 DOI: 10.9734/or/2022/v16i330234
Thiago Sande Miguel, Ermes Rodrigues Machado Filho, Bruna Sande Miguel, Daniel Almeida da Costa, Maurício B Pereira
Aims: To describe a Central Retinal Vein Occlusion Secondary to Paroxysmal Nocturnal Hemoglobinuria. Presentation of Case: A 25 years old, male, student, in regular follow-up in the Hematology sector due to Paroxysmal Nocturnal Hemoglobinuria in regular use of Eculizumab. He reports a month ago that he suddenly noticed, upon waking up in the morning, blurring and decreased visual acuity in her left eye. Discussion: Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired disorder characterized by hemolysis, thrombosis, and bone marrow failure caused by defective expression of glycosylphosphatidylinositol-anchored (GPI-anchored) complement inhibitors. Most commonly, PNH is caused by the loss of PIGA function, which is necessary for GPI biosynthesis. Conclusions: Patients with hemolytic anemia, unexplained thrombosis, especially in uncommon sites, cytopenias and bone marrow failure syndromes, dysphagia, and unexplained abdominal pain should be screened for PNH. PNH patients can benefit greatly from the treatments available, with a reduction in the risk of serious sequelae and a considerable improvement in their quality of life. So that the patient continues to be followed up in the ophthalmology department, with decreased visual acuity ipsilateral to the lesion, with a relative afferent pupillary defect on that side.
目的:描述继发于阵发性夜间血红蛋白尿的视网膜中央静脉阻塞。病例介绍:一名25岁,男性,学生,因阵发性夜间血红蛋白尿而定期使用Eculizumab,在血液学部门定期随访。他报告说,一个月前,他突然发现,早上醒来时,她的左眼模糊,视力下降。讨论:阵发性夜间血红蛋白尿(PNH)是一种获得性疾病,以溶血、血栓形成和骨髓衰竭为特征,由糖基磷脂酰肌醇锚定(gpi锚定)补体抑制剂表达缺陷引起。最常见的是,PNH是由PIGA功能丧失引起的,而PIGA功能是GPI生物合成所必需的。结论:有溶血性贫血、不明原因血栓形成(尤其是罕见部位)、细胞减少和骨髓衰竭综合征、吞咽困难、不明原因腹痛的患者应筛查PNH。PNH患者可以从现有的治疗中获益,减少严重后遗症的风险,并大大改善他们的生活质量。因此患者继续在眼科接受随访,病变同侧的视力下降,在那一侧有相对的瞳孔传入缺损。
{"title":"Central Retinal Vein Occlusion Secondary to Paroxysmal Nocturnal Hemoglobinuria","authors":"Thiago Sande Miguel, Ermes Rodrigues Machado Filho, Bruna Sande Miguel, Daniel Almeida da Costa, Maurício B Pereira","doi":"10.9734/or/2022/v16i330234","DOIUrl":"https://doi.org/10.9734/or/2022/v16i330234","url":null,"abstract":"Aims: To describe a Central Retinal Vein Occlusion Secondary to Paroxysmal Nocturnal Hemoglobinuria. \u0000Presentation of Case: A 25 years old, male, student, in regular follow-up in the Hematology sector due to Paroxysmal Nocturnal Hemoglobinuria in regular use of Eculizumab. He reports a month ago that he suddenly noticed, upon waking up in the morning, blurring and decreased visual acuity in her left eye. \u0000Discussion: Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired disorder characterized by hemolysis, thrombosis, and bone marrow failure caused by defective expression of glycosylphosphatidylinositol-anchored (GPI-anchored) complement inhibitors. Most commonly, PNH is caused by the loss of PIGA function, which is necessary for GPI biosynthesis. \u0000Conclusions: Patients with hemolytic anemia, unexplained thrombosis, especially in uncommon sites, cytopenias and bone marrow failure syndromes, dysphagia, and unexplained abdominal pain should be screened for PNH. PNH patients can benefit greatly from the treatments available, with a reduction in the risk of serious sequelae and a considerable improvement in their quality of life. So that the patient continues to be followed up in the ophthalmology department, with decreased visual acuity ipsilateral to the lesion, with a relative afferent pupillary defect on that side.","PeriodicalId":287685,"journal":{"name":"Ophthalmology Research: An International Journal","volume":"261 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134139605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Monochromatic Aberrations of the Cornea on Contrast Sensitivity under Photopic and Mesopic Conditions 角膜单色差对光和介观条件下对比敏感度的影响
Pub Date : 2022-05-04 DOI: 10.9734/or/2022/v16i230233
E. Pateras, K. Ladopoulos, P. Drakopoulos
Purpose: Vision is one of the most important senses. The first stage of vision is the creation of the observed object’s image on the retina. The quality of the retinal image is affected by several factors, such as   diffraction, sampling on the retina, chromatic aberration, scattering and higher order aberrations. The measurement of the quality is achieved both with subjective (visual acuity, contrast sensitivity) and objective methods (PSF, MTF, Strehl ratio, RMS). The purpose of this project is the measurement of higher order aberrations of the anterior corneal surface (with a Placido corneal topographer) and of the contrast sensitivity (with a Pelli Robson optotype). Then, we will try to find if there is a correlation between them. Methods and Materials: 20 persons participated in this survey, divided in two groups of 10 persons each. The first group (group 1) included subjects up to 39 years old and the second group (group 2) from 40 years and up. The participants didn’t have any pathological problems, except lower order refractive errors. Both eyes of each individual were included in the procedure. First, the higher order aberrations of the anterior corneal surface were measured, with the implementation of a Placido corneal topographer. This was followed by a measurement of the contrast sensitivity. The whole procedure took place under two lighting conditions, both photopic and mesopic. The examination presentation of the higher order aberrations is performed with the use of Zernike polynomials. Results: The results of the measuring procedure showed that for the first group, under photopic conditions (luminance 32.70 cd/m2) the mean value (± standard deviation) for the higher order aberrations RMS and decimal logarithm contrast sensitivity was 0.073 ± 0.018μm and 1.54 ± 0,16 (contrast 2.88 ± 1.24%) respectively. For the second group the corresponding values were 0.080 ± 0.036μm and 1.59 ± 0.16 (contrast 2.57 ± 1.24%). Accordingly, under mesopic conditions (luminance 1.14 cd/m2) the values for the first group were 0.252 ± 0.064 μm and 1.27 ± 0.15 (contrast 5.37 ± 2.06%), while for the second were 0.253 ± 0.069μm and 1.32 ± 0.12 (contrast 4.79 ± 1.35%). Spherical aberration and coma (horizontal and vertical) were also measured for both groups under photopic and mesopic conditions. The results showed that for the first group, under photopic conditions, RMS for coma and spherical aberration is 0.033 ± 0.014 μm and 0.022 ± 0.011 μm respectively, while for the second group 0.041 ± 0.027 μm and 0.024 ± 0.008 μm. Under mesopic conditions, the relevant results are 0.139 ± 0.065 μm and 0.124 ± 0.035μm for the first group and 0.149 ± 0.066 μm and 0.107 ± 0.038 μm for the second group. Finally, we should mention here that the equivalent defocus error corresponding to the higher order aberration RMS was estimated. The results for all the participants (without age separation), are 0.23 ± 0.09D (photopic conditions) and 0.28 ± 0.07D (mesopic conditions)
目的:视觉是最重要的感官之一。视觉的第一阶段是在视网膜上形成被观察物体的图像。视网膜图像的质量受衍射、视网膜上的采样、色差、散射和高阶像差等因素的影响。通过主观(视敏度、对比敏感度)和客观(PSF、MTF、Strehl比、RMS)两种方法来实现质量的测量。本项目的目的是测量角膜前表面的高阶像差(使用Placido角膜地形仪)和对比灵敏度(使用Pelli Robson光型)。然后,我们将尝试找出它们之间是否存在相关性。方法与材料:本次调查共20人,分为两组,每组10人。第一组(第一组)包括39岁以下的受试者,第二组(第二组)包括40岁及以上的受试者。除了低阶屈光不正外,参与者没有任何病理问题。每个人的两只眼睛都包括在手术中。首先,利用Placido角膜地形仪测量角膜前表面的高阶像差。接下来是对比敏感度的测量。整个过程在两种光照条件下进行,包括光和介光。用泽尼克多项式对高阶像差进行了检验。结果:测量程序结果表明,第一组在光度(32.70 cd/m2)条件下,高阶像差RMS平均值(±标准差)和十进制对数对比灵敏度分别为0.073±0.018μm和1.54±0.16(反差2.88±1.24%)。第二组分别为0.080±0.036μm和1.59±0.16 μm(对比2.57±1.24%)。因此,在中偏光度(亮度1.14 cd/m2)条件下,第一组的值分别为0.252±0.064 μm和1.27±0.15(对比度5.37±2.06%),第二组的值分别为0.253±0.069μm和1.32±0.12(对比度4.79±1.35%)。在光观和介观条件下,还测量了两组的球差和彗差(水平和垂直)。结果表明:第一组光致彗差和球差的RMS分别为0.033±0.014 μm和0.022±0.011 μm,第二组为0.041±0.027 μm和0.024±0.008 μm;在介观条件下,第一组的相关结果分别为0.139±0.065 μm和0.124±0.035μm,第二组的相关结果分别为0.149±0.066 μm和0.107±0.038 μm。最后,需要指出的是,对高阶像差RMS对应的等效离焦误差进行了估计。所有参与者(不区分年龄)的结果分别为0.23±0.09D(光性条件)和0.28±0.07D(介观条件)。结论:通过对结果的统计分析,我们得出左、右眼高阶像差存在对称性的结论。此外,年龄似乎并不是影响高阶像差大小差异的重要因素。对比灵敏度的测量也得出了类似的结论。此外,我们已经观察到,在光性和介观条件下,角膜前表面的高阶像差和对比灵敏度之间存在相关性。仅在光敏条件下,彗差和对比度之间也存在相关性。但球差与对比度之间无显著相关性。这两组的年龄差异对结果没有影响。最后,等效离焦太小,无论是在光性和介性条件下,还是在彼此之间,都不能具有临床意义。
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引用次数: 0
Congenital Ocular Melanocytosis: Case Report 先天性眼部黑色素细胞增多症1例
Pub Date : 2022-04-13 DOI: 10.9734/or/2022/v16i230231
Thiago Sande Miguel, Fernanda Bekman Diniz Mitleg Rocha, Tais Cristina Rossett, Felipe Bekman Diniz Mitleg Rocha, Eduardo F Damasceno, Daniel Almeida da Costa
Aims: To describe Congenital Ocular Melanocytosis. Presentation of Case: LPC, 7 years old, male, brown, with no previous comorbidities, was taken to the ophthalmology outpatient clinic of the Hospital Universitário Antônio Pedro, Brazil by parents who alleged the presence of bluish-looking lesions in the sclera of the child's right eye since birth. Discussion: Congenital Ocular Melanocytosis is a rare pathology characterized by an increase in the number, size and pigmentation of melanocytes. Its pathophysiological picture is unknown, but it is believed to be due to an alteration in the migration of melanocytes from the neural crest to the epidermis during the embryonic process. This condition can be complicated by glaucoma and uveal melanoma. Gonioscopy is essential in these cases to assess whether there is pigmentation of the trabeculae, so that the propaedeutics of investigation of glaucoma becomes essential in these patients, since 10% of cases can complicate this condition. Conclusions: Congenital Ocular Melanocytosis early in life and the importance of monitoring these patients should be emphasized. Comprehensive tests are important for early detection and treatment, in order to improve the prognosis and avoid more severe consequences than what can happen from melanocytosis.
目的:描述先天性眼部黑色素细胞增多症。病例介绍:LPC, 7岁,男性,棕色皮肤,以前没有合并症,被父母带到巴西Pedro医院Universitário Antônio眼科门诊,他们声称孩子的右眼巩膜自出生以来就存在蓝色病变。讨论:先天性眼部黑色素细胞增多症是一种罕见的病理,其特征是黑色素细胞的数量、大小和色素沉着增加。其病理生理机制尚不清楚,但据信是由于胚胎过程中黑素细胞从神经嵴向表皮的迁移发生了改变。这种情况可并发青光眼和葡萄膜黑色素瘤。在这些病例中,角膜镜检查对于评估小梁是否有色素沉着至关重要,因此在这些患者中,青光眼的研究变得至关重要,因为10%的病例会使这种情况复杂化。结论:先天性眼部黑素细胞增多症在早期发病,应重视对这些患者的监测。为了改善预后和避免比黑素细胞增多症更严重的后果,全面的检查对于早期发现和治疗非常重要。
{"title":"Congenital Ocular Melanocytosis: Case Report","authors":"Thiago Sande Miguel, Fernanda Bekman Diniz Mitleg Rocha, Tais Cristina Rossett, Felipe Bekman Diniz Mitleg Rocha, Eduardo F Damasceno, Daniel Almeida da Costa","doi":"10.9734/or/2022/v16i230231","DOIUrl":"https://doi.org/10.9734/or/2022/v16i230231","url":null,"abstract":"Aims: To describe Congenital Ocular Melanocytosis. \u0000Presentation of Case: LPC, 7 years old, male, brown, with no previous comorbidities, was taken to the ophthalmology outpatient clinic of the Hospital Universitário Antônio Pedro, Brazil by parents who alleged the presence of bluish-looking lesions in the sclera of the child's right eye since birth. \u0000Discussion: Congenital Ocular Melanocytosis is a rare pathology characterized by an increase in the number, size and pigmentation of melanocytes. Its pathophysiological picture is unknown, but it is believed to be due to an alteration in the migration of melanocytes from the neural crest to the epidermis during the embryonic process. This condition can be complicated by glaucoma and uveal melanoma. Gonioscopy is essential in these cases to assess whether there is pigmentation of the trabeculae, so that the propaedeutics of investigation of glaucoma becomes essential in these patients, since 10% of cases can complicate this condition. \u0000Conclusions: Congenital Ocular Melanocytosis early in life and the importance of monitoring these patients should be emphasized. Comprehensive tests are important for early detection and treatment, in order to improve the prognosis and avoid more severe consequences than what can happen from melanocytosis.","PeriodicalId":287685,"journal":{"name":"Ophthalmology Research: An International Journal","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132246527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Predictors of Anxiety and Depression among Glaucoma Patients in a Tertiary Health Institution in South-South Nigeria 尼日利亚南南三级卫生机构青光眼患者焦虑和抑郁的患病率和预测因素
Pub Date : 2022-04-11 DOI: 10.9734/or/2022/v16i230230
Nnenne N. Ani, Godswill Inye Nathaniel
Aim: To determine the prevalence and factors associated with Anxiety and Depression among `glaucoma patients. Study Design: It was a hospital-based cross-sectional study. Place and Duration of Study: This study was carried out at the Department of Ophthalmology, University of Port Harcourt Teaching Hospital Port Harcourt, Nigeria. From February to June 2016. Patients and Methods: Glaucoma patients aged 18 years or older with no history of coexisting ocular pathology or chronic systemic illness were included in the study. Hospital Anxiety and Depression Scale (HADS) questionnaires were administered. Ocular examinations done included visual acuity, applanation tonometry, and ophthalmoscopy. Perimetry was done using a standard achromatic perimetry with a fast threshold central 30-2 strategy. Data obtained from the subjects were analysed using SPSS (Version 20), and p value set at < 0.05. Results: There were 141 males (47%) and 158 females (53%) giving a male: female ratio 1:1.12. The age range was 20-86 years with mean age of 53.61± 14.23 years. The prevalence of Anxiety and Depression were 37.5% and 34.1% respectively, while 53 subjects (17.7%) had both anxiety and depression. The mean scores of anxiety and depression among the study subjects were 6.49±3.851 (CI 6.05-6.93) and 5.78±3.832 (95% CI 5.35-6.21) respectively. Family history (O.R=1.893;P-value=0.019), previous membership of a Glaucoma Society(O.R=2.633;P-value=0.007), and BCVA in the better eye(O.R=0.235;P-value=0.001), were significant predictors of anxiety while age(O.R=0.774;P-value=0.029), educational status (O.R=0.139;P-value=0.001), and BCVA in the better eye (O.R=4.865;P-value=0.001) were significant predictive factors for depression after adjustment for cofounding factors. Conclusion: There is high prevalence of Anxiety and Depression among this cohort of glaucoma patients. Combined management of glaucoma patients with Neuropsychiatrists will promote a holistic management with early detection of mental health challenges.
目的:了解青光眼患者焦虑、抑郁的患病率及相关因素。研究设计:这是一个以医院为基础的横断面研究。研究地点和时间:本研究在尼日利亚哈科特港大学哈科特港教学医院眼科进行。2016年2月至6月。患者和方法:年龄在18岁及以上,无眼部病理史或慢性全身性疾病的青光眼患者纳入研究。采用医院焦虑抑郁量表(HADS)进行问卷调查。眼部检查包括视力、眼压测量和检眼镜。采用快速阈值中心30-2策略的标准消色差视野法进行视野测量。使用SPSS (Version 20)对受试者数据进行分析,p值设为< 0.05。结果:男性141例(47%),女性158例(53%),男女比例为1:1.12。年龄20 ~ 86岁,平均53.61±14.23岁。焦虑和抑郁的患病率分别为37.5%和34.1%,同时存在焦虑和抑郁的53例(17.7%)。研究对象焦虑和抑郁的平均得分分别为6.49±3.851 (CI 6.05-6.93)和5.78±3.832 (95% CI 5.35-6.21)。家族史(O.R=1.893, p值=0.019)、既往青光眼协会会员(O.R=2.633, p值=0.007)和较好眼BCVA (O.R=0.235, p值=0.001)是焦虑的显著预测因素,而年龄(O.R=0.774, p值=0.029)、教育程度(O.R=0.139, p值=0.001)和较好眼BCVA (O.R=4.865, p值=0.001)是调整共同影响因素后抑郁的显著预测因素。结论:该青光眼患者焦虑和抑郁发生率较高。联合管理青光眼患者与神经精神病学家将促进整体管理与早期发现的精神健康挑战。
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引用次数: 0
Axenfeld-Rieger Syndrome: Case Report Axenfeld-Rieger综合征1例报告
Pub Date : 2022-03-12 DOI: 10.9734/or/2022/v16i230229
Amanda Dinalli Francisco, Thiago Sande Miguel, Ana Luiza Mansur Souto, Daniel Almeida da Costa, Maurício Bastos Pereira
Aims:To describe a Axenfeld-Rieger Syndrome. Presentation of Case: MCL, 7 years old, female, brown, was taken to the ophthalmology outpatient clinic of the Hospital Universitário Antônio Pedro, Brazil by her parents, complaining of low visual acuity and malformation of the pupil perceived since birth. Discussion: Axenfeld-Rieger Syndrome is a rare and hereditary disease. Clinically, Axenfeld's anomaly is characterized by the presence of posterior embryotoxon, and there may be adherence of iridian tissue in its periphery. In addition to Rieger's anomaly, posterior embryotoxon is added to iris hypoplasia and iris thickness defects, uveal ectropion and pupillary alterations, such as corectopia. Rieger's syndrome is associated with extraocular changes, of which hypodontia, myicrodontia, maxillary hypoplasia, telecanthus, hypertelorism and hypospadias stand out. Conclusions: Therefore, the importance of early diagnosis, follow-up and adequate treatment becomes evident in order to preserve the visual function of patients and thus avoid an unfavorable evolution.
目的:描述一种Axenfeld-Rieger综合征。病例介绍:MCL, 7岁,女,棕色皮肤,由父母带到巴西Pedro医院Universitário Antônio眼科门诊就诊,主诉视力低,出生后瞳孔畸形。讨论:Axenfeld-Rieger综合征是一种罕见的遗传性疾病。临床上,Axenfeld异常的特征是存在后胚胎毒瘤,其周围可能有虹膜组织粘附。除Rieger异常外,虹膜发育不全、虹膜厚度缺损、葡萄膜外翻、瞳孔改变、矫正异位症等也可发生后胚胎瘤。Rieger’s综合征与眼外病变有关,其中突出表现为牙下畸形、牙微畸形、上颌发育不全、远端畸形、远端肥大和尿道下裂。结论:早期诊断、随访和适当治疗对于保护患者的视觉功能,避免不良的发展具有重要意义。
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引用次数: 0
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Ophthalmology Research: An International Journal
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