Age-related macular degeneration (AMD) merupakan penyakit degeneratif makula yang mengakibatkan gangguan penglihatan sentral pada usia lanjut. AMD yang didapatkan pada sekitar 5,8% individu dengan kebutaan, merupakan penyebab kebutaan keempat terbanyak di dunia. Faktor risiko AMD meliputi usia, genetik, merokok, dan nutrisi. AMD diklasifikasikan menjadi AMD non-neovaskular (dry) dan neovaskular (wet). Pada tahap awal AMD sering tidak bergejala, pada tahap lanjut dapat ditemukan hilang penglihatan sentral disertai distorsi visual dengan gambaran drusen, geographic atrophy, atau neovaskularisasi koroid pada pemeriksaan fundus. Pencitraan retina diperlukan untuk menentukan tata laksana sesuai derajat penyakit. Penanganan AMD non-neovaskular saat ini ditekankan pada observasi dan kemampuan pasien untuk mengenali perubahan fungsi visual serta deteksi dini neovaskularisasi koroid. Modifikasi gaya hidup, seperti berhenti merokok dan suplementasi nutrisi, dapat dilakukan untuk mencegah progresivitas AMD. Terapi anti-VEGF (vascular endothelial growth factor) saat ini merupakan pilihan untuk tata laksana AMD neovaskular. Age-related macular degeneration (AMD) is a macular degenerative disease causing impaired central vision in elderly. AMD occurs in approximately 5.8% of individuals with blindness; it is the fourth leading cause of blindness in the world. The risk factors of AMD include age, genetics, smoking, and nutrition. AMD is classified into non-neovascular (dry) and neovascular (wet) AMD. Early AMD is often asymptomatic, loss of central vision with visual distortion can happen in the later stages. Drusen, geographic atrophy, or choroidal neovascularization can be observed in fundus examination. Retinal imaging is needed to determine management according to the stage of the disease. Current management of non-neovascular AMD is emphasized through observation and the patient’s ability to recognize changes in visual function as well as early detection of choroidal neovascularization. Lifestyle modifications such as smoking cessation and nutritional supplementation can prevent the progression of AMD. Anti-VEGF (vascular endothelial growth factor) therapy is currently an option for the management of neovascular AMD.
{"title":"Tinjauan atas Age-related Macular Degeneration","authors":"A. Dewi","doi":"10.55175/cdk.v50i7.953","DOIUrl":"https://doi.org/10.55175/cdk.v50i7.953","url":null,"abstract":"Age-related macular degeneration (AMD) merupakan penyakit degeneratif makula yang mengakibatkan gangguan penglihatan sentral pada usia lanjut. AMD yang didapatkan pada sekitar 5,8% individu dengan kebutaan, merupakan penyebab kebutaan keempat terbanyak di dunia. Faktor risiko AMD meliputi usia, genetik, merokok, dan nutrisi. AMD diklasifikasikan menjadi AMD non-neovaskular (dry) dan neovaskular (wet). Pada tahap awal AMD sering tidak bergejala, pada tahap lanjut dapat ditemukan hilang penglihatan sentral disertai distorsi visual dengan gambaran drusen, geographic atrophy, atau neovaskularisasi koroid pada pemeriksaan fundus. Pencitraan retina diperlukan untuk menentukan tata laksana sesuai derajat penyakit. Penanganan AMD non-neovaskular saat ini ditekankan pada observasi dan kemampuan pasien untuk mengenali perubahan fungsi visual serta deteksi dini neovaskularisasi koroid. Modifikasi gaya hidup, seperti berhenti merokok dan suplementasi nutrisi, dapat dilakukan untuk mencegah progresivitas AMD. Terapi anti-VEGF (vascular endothelial growth factor) saat ini merupakan pilihan untuk tata laksana AMD neovaskular.\u0000 \u0000Age-related macular degeneration (AMD) is a macular degenerative disease causing impaired central vision in elderly. AMD occurs in approximately 5.8% of individuals with blindness; it is the fourth leading cause of blindness in the world. The risk factors of AMD include age, genetics, smoking, and nutrition. AMD is classified into non-neovascular (dry) and neovascular (wet) AMD. Early AMD is often asymptomatic, loss of central vision with visual distortion can happen in the later stages. Drusen, geographic atrophy, or choroidal neovascularization can be observed in fundus examination. Retinal imaging is needed to determine management according to the stage of the disease. Current management of non-neovascular AMD is emphasized through observation and the patient’s ability to recognize changes in visual function as well as early detection of choroidal neovascularization. Lifestyle modifications such as smoking cessation and nutritional supplementation can prevent the progression of AMD. Anti-VEGF (vascular endothelial growth factor) therapy is currently an option for the management of neovascular AMD.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133708071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gastroesophageal reflux disease (GERD) merupakan salah satu penyakit gastrointestinal (GI) paling umum pada lanjut usia (lansia). Gejala GERD pada lansia umumnya atipikal dan tidak terlalu parah, namun lebih berisiko terjadi kelainan mukosa dan komplikasi. Proton pump inhibitor (PPI) masih menjadi sarana farmakoterapi terapi lini pertama pasien GERD lansia. Namun, penggunaan PPI pada lansia dikaitkan dengan beberapa efek samping. Hingga saat ini, belum ada konsensus mengenai durasi optimal penggunaan PPI pada lansia. Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal (GI) diseases in the elderly. GERD symptoms in the elderly are generally atypical and less severe, but with a higher risk of mucosal abnormalities and complications. Proton pump inhibitor (PPI) therapy is still the first line pharmacotherapy for elderly GERD patients. However, PPI use in elderly are associated with several side effects. To date, there is no consensus yet on the optimal duration of PPI use in the elderly.
胃食管反流病（GERD）是老年人最常见的胃肠道疾病之一。老年人胃食管反流病的症状通常不典型且不太严重，但更容易出现粘膜异常和并发症。质子泵抑制剂（PPIs）仍然是老年胃食管反流病患者的一线药物疗法。然而，老年人使用质子泵抑制剂会产生一些副作用。迄今为止，关于老年人使用 PPI 的最佳持续时间尚未达成共识。胃食管反流病（GERD）是老年人最常见的胃肠道疾病之一。老年人的胃食管反流病症状一般不典型，也不太严重，但出现粘膜异常和并发症的风险较高。质子泵抑制剂（PPI）疗法仍是老年胃食管反流病患者的一线药物疗法。然而，老年人使用 PPI 会产生一些副作用。迄今为止，关于老年人使用 PPI 的最佳持续时间尚未达成共识。
{"title":"Proton Pump Inhibitor (PPI) sebagai Farmakoterapi GERD pada Lansia","authors":"Josephine Herwita Atepela","doi":"10.55175/cdk.v50i7.635","DOIUrl":"https://doi.org/10.55175/cdk.v50i7.635","url":null,"abstract":"Gastroesophageal reflux disease (GERD) merupakan salah satu penyakit gastrointestinal (GI) paling umum pada lanjut usia (lansia). Gejala GERD pada lansia umumnya atipikal dan tidak terlalu parah, namun lebih berisiko terjadi kelainan mukosa dan komplikasi. Proton pump inhibitor (PPI) masih menjadi sarana farmakoterapi terapi lini pertama pasien GERD lansia. Namun, penggunaan PPI pada lansia dikaitkan dengan beberapa efek samping. Hingga saat ini, belum ada konsensus mengenai durasi optimal penggunaan PPI pada lansia.\u0000 \u0000Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal (GI) diseases in the elderly. GERD symptoms in the elderly are generally atypical and less severe, but with a higher risk of mucosal abnormalities and complications. Proton pump inhibitor (PPI) therapy is still the first line pharmacotherapy for elderly GERD patients. However, PPI use in elderly are associated with several side effects. To date, there is no consensus yet on the optimal duration of PPI use in the elderly.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"265 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133357092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Akne vulgaris merupakan gangguan inflamasi kronis unit kelenjar pilosebasea. Probiotik merupakan mikroorganisme hidup yang dapat menguntungkan tubuh. Teori gut-brain-skin oleh Stokes dan Pilssbury pada tahun 1930 menunjukkan hubungan antara saluran pencernaan, otak, dan kulit. Probiotik berpengaruh baik pada tata laksana akne vulgaris melalui efek anti inflamasinya. Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous unit. Probiotics are live microorganisms with beneficial effects. The gutbrain-skin theory first described by Stokes and Pillsbury in 1930 showed the relationship between the gastrointestinal tract, brain, and skin. Probiotics have a role on acne vulgaris management due to its anti-inflammatory effect.
{"title":"Peran Probiotik pada Terapi Akne Vulgaris","authors":"Maichika Susanto","doi":"10.55175/cdk.v50i7.958","DOIUrl":"https://doi.org/10.55175/cdk.v50i7.958","url":null,"abstract":"Akne vulgaris merupakan gangguan inflamasi kronis unit kelenjar pilosebasea. Probiotik merupakan mikroorganisme hidup yang dapat menguntungkan tubuh. Teori gut-brain-skin oleh Stokes dan Pilssbury pada tahun 1930 menunjukkan hubungan antara saluran pencernaan, otak, dan kulit. Probiotik berpengaruh baik pada tata laksana akne vulgaris melalui efek anti inflamasinya.\u0000 \u0000Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous unit. Probiotics are live microorganisms with beneficial effects. The gutbrain-skin theory first described by Stokes and Pillsbury in 1930 showed the relationship between the gastrointestinal tract, brain, and skin. Probiotics have a role on acne vulgaris management due to its anti-inflammatory effect.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127399614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ibu hamil rentan mengalami infeksi yang berujung sepsis akibat perubahan fisiologis signifikan berbagai sistem organ. Penyebab sepsis dalam kehamilan tersering bersumber dari saluran kemih, yang disebut urosepsis dengan tingkat mortalitas mencapai 20%–42%. Selain mengancam ibu hamil, sepsis juga berpotensi mengancam kesejahteraan janin. Oleh karena itu, diagnosis dan manajemen sepsis secara dini pada kehamilan sangatlah penting untuk mencegah morbiditas dan mortalitas janin dan ibu. Namun, panduan penatalaksanaan komprehensif sepsis pada kehamilan masih terbatas dan terpencar, sehingga membuat sulit dipahami. Tinjauan pustaka ini dibuat melalui penulusuran bukti ilmiah secara holistik untuk memberikan pemahaman mengenai konsep dasar urosepsis. Aspek diagnosis dan manajemen dirangkum secara komprehensif melalui ilustrasi dan algoritma yang mudah dipahami disertai dengan sistem skoring berkaitan dengan diagnosis dan pilihan terapi farmakologi untuk menangani urosepsis. Pregnant women are susceptible to infections that lead to sepsis due to significant physiological changes in various organ systems. The most common cause of infection in sepsis in pregnancy comes from the urinary tract, called urosepsis, with a mortality rate of 20%–42%. Sepsis also has the potential to endanger the fetus. This issue indicates that early diagnosis and management of sepsis in pregnancy is crucial to prevent fetal and maternal morbidity and mortality. Nonetheless, comprehensive guidelines for managing sepsis in pregnancy are still limited and scattered, making them difficult to understand. This literature review was created through a holistic appraisal of scientific evidence to understand the basic concepts of urosepsis. Aspects of diagnosis and management were summarised through illustrations and algorithms accompanied by scoring system related to diagnosis and pharmacological therapy.
{"title":"Manajemen Komprehensif Sepsis Akibat Infeksi Saluran Kemih pada Kehamilan","authors":"M. Habiburrahman, Afid Brilliana Putra","doi":"10.55175/cdk.v50i6.919","DOIUrl":"https://doi.org/10.55175/cdk.v50i6.919","url":null,"abstract":"Ibu hamil rentan mengalami infeksi yang berujung sepsis akibat perubahan fisiologis signifikan berbagai sistem organ. Penyebab sepsis dalam kehamilan tersering bersumber dari saluran kemih, yang disebut urosepsis dengan tingkat mortalitas mencapai 20%–42%. Selain mengancam ibu hamil, sepsis juga berpotensi mengancam kesejahteraan janin. Oleh karena itu, diagnosis dan manajemen sepsis secara dini pada kehamilan sangatlah penting untuk mencegah morbiditas dan mortalitas janin dan ibu. Namun, panduan penatalaksanaan komprehensif sepsis pada kehamilan masih terbatas dan terpencar, sehingga membuat sulit dipahami. Tinjauan pustaka ini dibuat melalui penulusuran bukti ilmiah secara holistik untuk memberikan pemahaman mengenai konsep dasar urosepsis. Aspek diagnosis dan manajemen dirangkum secara komprehensif melalui ilustrasi dan algoritma yang mudah dipahami disertai dengan sistem skoring berkaitan dengan diagnosis dan pilihan terapi farmakologi untuk menangani urosepsis. \u0000 \u0000Pregnant women are susceptible to infections that lead to sepsis due to significant physiological changes in various organ systems. The most common cause of infection in sepsis in pregnancy comes from the urinary tract, called urosepsis, with a mortality rate of 20%–42%. Sepsis also has the potential to endanger the fetus. This issue indicates that early diagnosis and management of sepsis in pregnancy is crucial to prevent fetal and maternal morbidity and mortality. Nonetheless, comprehensive guidelines for managing sepsis in pregnancy are still limited and scattered, making them difficult to understand. This literature review was created through a holistic appraisal of scientific evidence to understand the basic concepts of urosepsis. Aspects of diagnosis and management were summarised through illustrations and algorithms accompanied by scoring system related to diagnosis and pharmacological therapy.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126061024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abortus imminens adalah perdarahan yang terjadi sebelum usia kehamilan 20 minggu, tanpa keluarnya janin. Selama kehamilan, progesteron berperan dalam proses implantasi janin ke dalam rahim. Beberapa penelitian menunjukkan bahwa progesteron bermanfaat dalam penanganan abortus imminens, baik dalam bentuk oral maupun supositoria. Sediaan oral terbukti lebih efektif dibandingkan progesteron vaginal. Threatened miscarriage or imminent abortion is vaginal bleeding that happened before a 20-week gestation without fetus expulsion. During pregnancy, progesterone plays a role in the process of implanting the fetus into the uterus. Several studies have shown that oral and suppository progesterone are beneficial for imminent abortion treatment, both in oral and suppository form. Oral preparations have proved to be more effective than vaginal progesterone.
{"title":"Efektivitas Progesteron Oral dan Vagina pada Tata Laksana Abortus Imminens","authors":"Pika Novriani Lubis","doi":"10.55175/cdk.v50i6.922","DOIUrl":"https://doi.org/10.55175/cdk.v50i6.922","url":null,"abstract":"Abortus imminens adalah perdarahan yang terjadi sebelum usia kehamilan 20 minggu, tanpa keluarnya janin. Selama kehamilan, progesteron berperan dalam proses implantasi janin ke dalam rahim. Beberapa penelitian menunjukkan bahwa progesteron bermanfaat dalam penanganan abortus imminens, baik dalam bentuk oral maupun supositoria. Sediaan oral terbukti lebih efektif dibandingkan progesteron vaginal. \u0000Threatened miscarriage or imminent abortion is vaginal bleeding that happened before a 20-week gestation without fetus expulsion. During pregnancy, progesterone plays a role in the process of implanting the fetus into the uterus. Several studies have shown that oral and suppository progesterone are beneficial for imminent abortion treatment, both in oral and suppository form. Oral preparations have proved to be more effective than vaginal progesterone.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132714374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ikterus atau jaundice sering dijumpai pada neonatus dan bayi. Ikterus dapat bersifat fisiologis atau patologis. Pada dasarnya, ikterus merupakan manifestasi klinis peningkatan kadar bilirubin dalam darah atau hiperbilirubinemia. Peningkatan bilirubin yang berlebihan berpotensi toksik dan dapat menyebabkan kematian. Pendekatan klinis yang baik dan terarah sangat penting untuk menentukan secara cepat dan tepat perlunya evaluasi dan intervensi medis lanjutan. Icterus or jaundice is a clinical symptom often found in neonates and infants. The condition might arise from physiological or pathological causes. Jaundice is a clinical manifestation signifying an elevated blood level of bilirubin (hyperbilirubinemia). Excessive increase in bilirubin is potentially toxic and might even lead to death. A good and directed clinical approach is very important to evaluate the need for further medical intervention.
{"title":"Pendekatan Klinis Neonatus dan Bayi Ikterus","authors":"Stephanie Taneysa Widodo, Theddyon Bhenlie Apry Kusbin","doi":"10.55175/cdk.v50i6.921","DOIUrl":"https://doi.org/10.55175/cdk.v50i6.921","url":null,"abstract":"Ikterus atau jaundice sering dijumpai pada neonatus dan bayi. Ikterus dapat bersifat fisiologis atau patologis. Pada dasarnya, ikterus merupakan manifestasi klinis peningkatan kadar bilirubin dalam darah atau hiperbilirubinemia. Peningkatan bilirubin yang berlebihan berpotensi toksik dan dapat menyebabkan kematian. Pendekatan klinis yang baik dan terarah sangat penting untuk menentukan secara cepat dan tepat perlunya evaluasi dan intervensi medis lanjutan. \u0000Icterus or jaundice is a clinical symptom often found in neonates and infants. The condition might arise from physiological or pathological causes. Jaundice is a clinical manifestation signifying an elevated blood level of bilirubin (hyperbilirubinemia). Excessive increase in bilirubin is potentially toxic and might even lead to death. A good and directed clinical approach is very important to evaluate the need for further medical intervention.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128848626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pandit Bagus Tri Saputra, Ariikah Dyah Lamara, Mahendra Eko Saputra, Rakha Achmad Maulana, Irien Eko Hermawati, Hanang Anugrawan Achmad, Rachmat Ageng Prastowo, Yudi Her Oktaviono
Pada tahun 2019, hipertensi diderita oleh 1,28 milyar jiwa di seluruh dunia dan diperkirakan terus meningkat setiap tahun. Saat ini, hipertensi masih menjadi salah satu penyebab utama morbiditas dan mortalitas global. Terdapat perubahan paradigma diagnosis hipertensi menjadi lebih direkomendasikan dengan pemeriksaan tekanan darah di luar klinik (out-of-office blood pressure measurement) berupa pemeriksaan tekanan darah ambulatoar (PTDA) jika fasilitas memadai atau pemeriksaan tekanan darah di rumah (PTDR) pada fasilitas lebih terbatas. Manajemen pasien hipertensi berfokus pada kontrol tekanan darah untuk meningkatkan kualitas hidup serta menurunkan angka kecacatan dan kematian dengan terapi farmakologis dan non-farmakologis. Terapi non-farmakologis telah terbukti membantu mengontrol tekanan darah, menurunkan morbiditas dan mortalitas, baik individu hipertensi maupun individu normal. In 2019, hypertension was suffered by 1.28 billion people worldwide and is expected to increase every year. Hypertension is still one of the main causes of global morbidity and mortality. There is a paradigm shift that diagnosis of hypertension is more recommended by out-of-office blood pressure measurement. Blood pressure measurements outside clinic can be done with ambulatory blood pressure or home blood pressure in limited facilities. Management of hypertensive patients focuses on blood pressure control with pharmacological and non-pharmacological method to improve quality of life, as well as to reduce morbidity and mortality. Non-pharmacological approach has been proven to optimize blood pressure control, to reduce morbidity and mortality in both hypertensive and normal individuals.
{"title":"Diagnosis dan Terapi Non-farmakologis pada Hipertensi","authors":"Pandit Bagus Tri Saputra, Ariikah Dyah Lamara, Mahendra Eko Saputra, Rakha Achmad Maulana, Irien Eko Hermawati, Hanang Anugrawan Achmad, Rachmat Ageng Prastowo, Yudi Her Oktaviono","doi":"10.55175/cdk.v50i6.624","DOIUrl":"https://doi.org/10.55175/cdk.v50i6.624","url":null,"abstract":"Pada tahun 2019, hipertensi diderita oleh 1,28 milyar jiwa di seluruh dunia dan diperkirakan terus meningkat setiap tahun. Saat ini, hipertensi masih menjadi salah satu penyebab utama morbiditas dan mortalitas global. Terdapat perubahan paradigma diagnosis hipertensi menjadi lebih direkomendasikan dengan pemeriksaan tekanan darah di luar klinik (out-of-office blood pressure measurement) berupa pemeriksaan tekanan darah ambulatoar (PTDA) jika fasilitas memadai atau pemeriksaan tekanan darah di rumah (PTDR) pada fasilitas lebih terbatas. Manajemen pasien hipertensi berfokus pada kontrol tekanan darah untuk meningkatkan kualitas hidup serta menurunkan angka kecacatan dan kematian dengan terapi farmakologis dan non-farmakologis. Terapi non-farmakologis telah terbukti membantu mengontrol tekanan darah, menurunkan morbiditas dan mortalitas, baik individu hipertensi maupun individu normal.\u0000 \u0000In 2019, hypertension was suffered by 1.28 billion people worldwide and is expected to increase every year. Hypertension is still one of the main causes of global morbidity and mortality. There is a paradigm shift that diagnosis of hypertension is more recommended by out-of-office blood pressure measurement. Blood pressure measurements outside clinic can be done with ambulatory blood pressure or home blood pressure in limited facilities. Management of hypertensive patients focuses on blood pressure control with pharmacological and non-pharmacological method to improve quality of life, as well as to reduce morbidity and mortality. Non-pharmacological approach has been proven to optimize blood pressure control, to reduce morbidity and mortality in both hypertensive and normal individuals.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127638040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liken amiloidosis adalah bentuk umum amiloidosis kulit primer yang sering didapatkan pada populasi di Amerika Tengah dan Selatan, Timur Tengah, dan Asia. Penyebabnya tidak diketahui, diperkirakan oleh garukan didukung faktor genetik dan faktor virus. Diagnosis dikonfirmasi dengan deteksi deposit amiloid di dermis papiler. Pilihan terapi adalah dengan steroid topikal atau intralesi, antihistamin, agen retinoid, dan terapi terbaru laser dermabrasi. Prognosis umumnya baik, pada beberapa kasus mengakibatkan rasa gatal kronis yang dapat mengganggu kualitas hidup. Lichen amyloidosis is a common form of primary cutaneous amyloidosis, occurs mainly in Central and South America, the Middle East, and Asia. The cause is unknown, it is thought to be caused by scratching supported by genetic factors and viral factors. Diagnosis is confirmed by the detection of amyloid deposits in the papillary dermis. Treatment are with topical or intralesional steroids, antihistamines, retinoid agents, and laser dermabrasion. Prognosis is generally good, but in some cases, caused chronic itching that can interfere with the patient’s quality of life.
{"title":"Liken Amiloidosis - Diagnosis dan Terapi","authors":"Angelia Carolin, Putu Dyah Ayu Saraswati","doi":"10.55175/cdk.v50i6.917","DOIUrl":"https://doi.org/10.55175/cdk.v50i6.917","url":null,"abstract":"Liken amiloidosis adalah bentuk umum amiloidosis kulit primer yang sering didapatkan pada populasi di Amerika Tengah dan Selatan, Timur Tengah, dan Asia. Penyebabnya tidak diketahui, diperkirakan oleh garukan didukung faktor genetik dan faktor virus. Diagnosis dikonfirmasi dengan deteksi deposit amiloid di dermis papiler. Pilihan terapi adalah dengan steroid topikal atau intralesi, antihistamin, agen retinoid, dan terapi terbaru laser dermabrasi. Prognosis umumnya baik, pada beberapa kasus mengakibatkan rasa gatal kronis yang dapat mengganggu kualitas hidup. \u0000 \u0000Lichen amyloidosis is a common form of primary cutaneous amyloidosis, occurs mainly in Central and South America, the Middle East, and Asia. The cause is unknown, it is thought to be caused by scratching supported by genetic factors and viral factors. Diagnosis is confirmed by the detection of amyloid deposits in the papillary dermis. Treatment are with topical or intralesional steroids, antihistamines, retinoid agents, and laser dermabrasion. Prognosis is generally good, but in some cases, caused chronic itching that can interfere with the patient’s quality of life.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"222 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131463370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramadhany Fikri Setiawan, K. Suryoadji, Brastho Bramantyo, Widayat Alviandi
Latar Belakang: Tinnitus retraining therapy (TRT), yang terdiri dari counseling therapy dan acoustic therapy, menjadi salah satu alternatif terapi tinitus. Namun, efektivitas TRT belum diketahui pasti. Tujuan: Mengetahui efektivitas TRT dalam meningkatkan kualitas hidup pasien tinitus. Metode: Laporan kasus berbasis bukti dengan mencari literatur dari pertanyaan klinis pada database Cochrane Library, Embase, ProQuest, PubMed, ScienceDirect, dan Scopus, dengan kata kunci sesuai pertanyaan klinis. Seleksi berdasarkan kriteria eligibilitas dan kesesuaian PICO, menghasilkan satu artikel kajian sistematik dan meta-analisis. Studi telah lolos telaah kritis sesuai pedoman Centre for Evidence-Based Medicine (CEBM) University of Oxford. Hasil: TRT memiliki overall response rate lebih tinggi dibandingkan terapi standar pada pasien tinitus (OR=7,01; IK 95%=5.16,9.53; p<0,00001; I2=0%; p=0,82). TRT memiliki skor tinnitus handicap inventory (THI) lebih rendah dibandingkan dengan terapi standar pada pasien tinitus (MD=-14.50; IK 95%=-16.65,-12.36; p<0,00001; I2= 8%; p=0,30). Simpulan: TRT efektif memperbaiki response rate terhadap tinitus dan menurunkan skor THI. Background: Tinnitus greatly affects daily activities, which can interfere with the quality of life. Tinnitus retraining therapy (TRT) which consists of counseling therapy and acoustic therapy, is an alternative therapy for tinnitus. However, its effectiveness is not yet known. Objective: To determine the effectivity of TRT in improving the quality of life of tinnitus patients. Methods: This study is an evidence-based case report that searches the literature from clinical questions in databases from Cochrane Library, Embase, ProQuest, PubMed, ScienceDirect, and Scopus, using keywords that matched the clinical question. Studies were selected based on the PICO and eligibility criteria. The result is one systematic review and meta-analysis article. The study has been critically appraised using the Center for Evidence-Based Medicine (CEBM) University of Oxford instruments. Result: TRT has a higher overall response rate than standard therapy in tinnitus patients (OR=7.01; CI 95%=5.16, 9.53; p<0.00001; I2=0%, p=0.82). TRT has a lower tinnitus handicap inventory (THI) scale than standard therapy in tinnitus patients (MD=-14.50; CI 95%=-16.65,-12.36; p<0.00001; I2= 8%; p=0.30). Conclusion: TRT effectively improves response rate to tinnitus and lowers THI score.
{"title":"Efektivitas Tinnitus Retraining Therapy (TRT) sebagai Upaya Meningkatkan Kualitas Hidup Pasien Tinitus: Laporan Kasus Berbasis Bukti","authors":"Ramadhany Fikri Setiawan, K. Suryoadji, Brastho Bramantyo, Widayat Alviandi","doi":"10.55175/cdk.v50i5.890","DOIUrl":"https://doi.org/10.55175/cdk.v50i5.890","url":null,"abstract":"Latar Belakang: Tinnitus retraining therapy (TRT), yang terdiri dari counseling therapy dan acoustic therapy, menjadi salah satu alternatif terapi tinitus. Namun, efektivitas TRT belum diketahui pasti. Tujuan: Mengetahui efektivitas TRT dalam meningkatkan kualitas hidup pasien tinitus. Metode: Laporan kasus berbasis bukti dengan mencari literatur dari pertanyaan klinis pada database Cochrane Library, Embase, ProQuest, PubMed, ScienceDirect, dan Scopus, dengan kata kunci sesuai pertanyaan klinis. Seleksi berdasarkan kriteria eligibilitas dan kesesuaian PICO, menghasilkan satu artikel kajian sistematik dan meta-analisis. Studi telah lolos telaah kritis sesuai pedoman Centre for Evidence-Based Medicine (CEBM) University of Oxford. Hasil: TRT memiliki overall response rate lebih tinggi dibandingkan terapi standar pada pasien tinitus (OR=7,01; IK 95%=5.16,9.53; p<0,00001; I2=0%; p=0,82). TRT memiliki skor tinnitus handicap inventory (THI) lebih rendah dibandingkan dengan terapi standar pada pasien tinitus (MD=-14.50; IK 95%=-16.65,-12.36; p<0,00001; I2= 8%; p=0,30). Simpulan: TRT efektif memperbaiki response rate terhadap tinitus dan menurunkan skor THI.\u0000 \u0000Background: Tinnitus greatly affects daily activities, which can interfere with the quality of life. Tinnitus retraining therapy (TRT) which consists of counseling therapy and acoustic therapy, is an alternative therapy for tinnitus. However, its effectiveness is not yet known. Objective: To determine the effectivity of TRT in improving the quality of life of tinnitus patients. Methods: This study is an evidence-based case report that searches the literature from clinical questions in databases from Cochrane Library, Embase, ProQuest, PubMed, ScienceDirect, and Scopus, using keywords that matched the clinical question. Studies were selected based on the PICO and eligibility criteria. The result is one systematic review and meta-analysis article. The study has been critically appraised using the Center for Evidence-Based Medicine (CEBM) University of Oxford instruments. Result: TRT has a higher overall response rate than standard therapy in tinnitus patients (OR=7.01; CI 95%=5.16, 9.53; p<0.00001; I2=0%, p=0.82). TRT has a lower tinnitus handicap inventory (THI) scale than standard therapy in tinnitus patients (MD=-14.50; CI 95%=-16.65,-12.36; p<0.00001; I2= 8%; p=0.30). Conclusion: TRT effectively improves response rate to tinnitus and lowers THI score.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133458340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Myxoma jantung merupakan tumor jantung jinak primer yang paling umum, biasanya ada di atrium kiri dengan titik perlekatan di daerah fossa ovalis. Modalitas pencitraan untuk diagnosis myxoma jantung di antaranya ekokardiografi, computed tomography (CT), magnetic resonance imaging (MRI). Cardiac myxoma is the most common primary benign heart tumor, usually in the left atrium with an attachment point in the fossa ovalis area. Many imaging modalities for cardiac myxoma diagnosis include echocardiography, computed tomography (CT), and magnetic resonance imaging (MRI).
{"title":"Modalitas Pencitraan untuk Diagnosis Myxoma Jantung","authors":"Hadiyanti","doi":"10.55175/cdk.v50i5.894","DOIUrl":"https://doi.org/10.55175/cdk.v50i5.894","url":null,"abstract":"Myxoma jantung merupakan tumor jantung jinak primer yang paling umum, biasanya ada di atrium kiri dengan titik perlekatan di daerah fossa ovalis. Modalitas pencitraan untuk diagnosis myxoma jantung di antaranya ekokardiografi, computed tomography (CT), magnetic resonance imaging (MRI).\u0000 \u0000Cardiac myxoma is the most common primary benign heart tumor, usually in the left atrium with an attachment point in the fossa ovalis area. Many imaging modalities for cardiac myxoma diagnosis include echocardiography, computed tomography (CT), and magnetic resonance imaging (MRI).","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130889941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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