Gangguan neurologis pasca-COVID-19 atau juga dikenal sebagai post-covid neurology syndrome (PCNS) merupakan sebuah kesatuan dari long COVID mencakup berbagai masalah kesehatan yang dapat berlangsung selama beberapa minggu hingga beberapa bulan bahkan mencapai tahunan. Gangguan neurologis ini dapat bervariasi seperti post-COVID fatigue syndrome, gangguan kognitif, anosmia dan ageusia, nyeri kepala, ataupun penyakit seperti stroke dan GBS yang masih memerlukan penelitian lebih lanjut mengenai mekanismenya. Hingga saat ini, belum ada pemeriksaan diagnostik yang pasti, sehingga anamnesis dan pemeriksaan fisik harus tepat. Tata laksana lanjutan diberikan sesuai dengan keluhan.
{"title":"Gangguan Neurologis Pasca-COVID-19","authors":"Patricia Michelle Lukito, Budi Riyanto Wreksoatmodjo","doi":"10.55175/cdk.v51i8.1532","DOIUrl":"https://doi.org/10.55175/cdk.v51i8.1532","url":null,"abstract":"Gangguan neurologis pasca-COVID-19 atau juga dikenal sebagai post-covid neurology syndrome (PCNS) merupakan sebuah kesatuan dari long COVID mencakup berbagai masalah kesehatan yang dapat berlangsung selama beberapa minggu hingga beberapa bulan bahkan mencapai tahunan. Gangguan neurologis ini dapat bervariasi seperti post-COVID fatigue syndrome, gangguan kognitif, anosmia dan ageusia, nyeri kepala, ataupun penyakit seperti stroke dan GBS yang masih memerlukan penelitian lebih lanjut mengenai mekanismenya. Hingga saat ini, belum ada pemeriksaan diagnostik yang pasti, sehingga anamnesis dan pemeriksaan fisik harus tepat. Tata laksana lanjutan diberikan sesuai dengan keluhan.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"107 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141926854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by symmetrical joint involvement and extra-articular manifestations. Methotrexate and leflunomide are disease modifying anti-rheumatic drugs(DMARD) and use as treatment options for rheumatoid arthritis. This report aims to compare the effectiveness of leflunomide with methotrexate as therapy for rheumatoid arthritis. Methods: Literature search was carried out through three electronic databases: PubMed, Cochrane, and EBSCOHost with specific keywords based on PICO. Selection was in accordance with inclusion and exclusion criteria based on the clinical question. Selected literature was critically reviewed using an adapted instrument from the University of Oxford’s CEBM. Result: One systematic review and meta-analysis literature by Alfaro-Lara, et al, (2017) was obtained. The results showed a trend towards methotrexate in achieving response according to American College of Rheumatology (ACR20) (0.88 [95% CI: 0.74-1.06]; p = 0.18), reduction in joint swelling was greater with methotrexate (-0.82 [95% CI: 0.24-1.39]; p = 0.006), no significant difference in joint pain reduction (p>0.05). Liver enzyme elevations were more frequent with leflunomide (0.38 [0.27-0.53]; p = 0.007); gastrointestinal (GI) complaints were more frequent with methotrexate (1.44 [1.17-1.79]; p = 0.0007), no significant difference in the incidence of non-severe infections. Conclusion: Leflunomide has the same efficacy as methotrexate for RA therapy; more reduction of joint swelling with methotrexate. Leflunomide was associated with greater increases in liver enzymes, but fewer GI complaints.
{"title":"Comparison of Effectiveness of Leflunomide with Methotrexate for Rheumatoid Arthritis Therapy","authors":"Kemal Akbar Suryoadji, Pramesti Kusumadini Wibowo","doi":"10.55175/cdk.v51i8.1053","DOIUrl":"https://doi.org/10.55175/cdk.v51i8.1053","url":null,"abstract":"Background: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by symmetrical joint involvement and extra-articular manifestations. Methotrexate and leflunomide are disease modifying anti-rheumatic drugs(DMARD) and use as treatment options for rheumatoid arthritis. This report aims to compare the effectiveness of leflunomide with methotrexate as therapy for rheumatoid arthritis. Methods: Literature search was carried out through three electronic databases: PubMed, Cochrane, and EBSCOHost with specific keywords based on PICO. Selection was in accordance with inclusion and exclusion criteria based on the clinical question. Selected literature was critically reviewed using an adapted instrument from the University of Oxford’s CEBM. Result: One systematic review and meta-analysis literature by Alfaro-Lara, et al, (2017) was obtained. The results showed a trend towards methotrexate in achieving response according to American College of Rheumatology (ACR20) (0.88 [95% CI: 0.74-1.06]; p = 0.18), reduction in joint swelling was greater with methotrexate (-0.82 [95% CI: 0.24-1.39]; p = 0.006), no significant difference in joint pain reduction (p>0.05). Liver enzyme elevations were more frequent with leflunomide (0.38 [0.27-0.53]; p = 0.007); gastrointestinal (GI) complaints were more frequent with methotrexate (1.44 [1.17-1.79]; p = 0.0007), no significant difference in the incidence of non-severe infections. Conclusion: Leflunomide has the same efficacy as methotrexate for RA therapy; more reduction of joint swelling with methotrexate. Leflunomide was associated with greater increases in liver enzymes, but fewer GI complaints.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"50 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141929273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Osteomyelitis is a bacterial infection in bone or bone marrow. This study was a retrospective descriptive study of chronic osteomyelitis cases at Kartika Husada Level II Army Hospital of Kubu Raya Regency from January 2015 to December 2017 as well as a description of its management. There were 47 subjects taken based on their medical records. Surgical management was done in 39 cases (83.0%), consisting of debridement and sequestrectomy (33 cases), debridement (4 cases), and amputation (2 cases). Surgical management was combined with non-surgical management.
{"title":"Overview of Chronic Osteomyelitis Cases at Level II Kartika Husada Hospital, Kubu Raya Regency, West Kalimantan Province January 2015 - December 2017","authors":"Cahayo Mahandro Mahandro, Ganda Mrh Purba, Ery Hermawati","doi":"10.55175/cdk.v51i8.966","DOIUrl":"https://doi.org/10.55175/cdk.v51i8.966","url":null,"abstract":"Osteomyelitis is a bacterial infection in bone or bone marrow. This study was a retrospective descriptive study of chronic osteomyelitis cases at Kartika Husada Level II Army Hospital of Kubu Raya Regency from January 2015 to December 2017 as well as a description of its management. There were 47 subjects taken based on their medical records. Surgical management was done in 39 cases (83.0%), consisting of debridement and sequestrectomy (33 cases), debridement (4 cases), and amputation (2 cases). Surgical management was combined with non-surgical management.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"12 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141928533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Pneumonia is still one of the common causes of death in children under 5 years old in low-middle-income countries. The common cause of pneumonia is bacteria, requiring antibiotics as treatment. This systematic review evaluates the efficacy of amoxicillin and cotrimoxazole in treating pneumonia. Methods: This systematic review used PRISMA rules to analyze Pubmed and Europe PMC articles. The dose, duration, and therapeutic failure of amoxicillin and cotrimoxazole were assessed. Results: A total of 336 articles were selected for title and abstract screening. Four articles met the requirements, and two were selected for systematic review analysis. A total of 20,646 patients were analyzed, 11,633 (56.3%) received amoxicillin and 9,013 (43.7%) received cotrimoxazole. There was no significant difference in treatment failure between amoxicillin and cotrimoxazole. Conclusion: Amoxicillin has the same efficacy as cotrimoxazole for the management of non-severe pneumonia in children under 5 years old.
{"title":"Amoxicillin versus Cotrimoxazole for Treating Non-severe Pneumonia: A Systematic Review","authors":"Riana Suwarni, Anjar Nuryanto","doi":"10.55175/cdk.v51i8.1225","DOIUrl":"https://doi.org/10.55175/cdk.v51i8.1225","url":null,"abstract":"Introduction: Pneumonia is still one of the common causes of death in children under 5 years old in low-middle-income countries. The common cause of pneumonia is bacteria, requiring antibiotics as treatment. This systematic review evaluates the efficacy of amoxicillin and cotrimoxazole in treating pneumonia. Methods: This systematic review used PRISMA rules to analyze Pubmed and Europe PMC articles. The dose, duration, and therapeutic failure of amoxicillin and cotrimoxazole were assessed. Results: A total of 336 articles were selected for title and abstract screening. Four articles met the requirements, and two were selected for systematic review analysis. A total of 20,646 patients were analyzed, 11,633 (56.3%) received amoxicillin and 9,013 (43.7%) received cotrimoxazole. There was no significant difference in treatment failure between amoxicillin and cotrimoxazole. Conclusion: Amoxicillin has the same efficacy as cotrimoxazole for the management of non-severe pneumonia in children under 5 years old.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"116 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141926359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Morbus Hansen (MH), or leprosy, is a chronic granulomatous infection caused by Mycobacterium leprae. This disease still has a negative stigma, leading to ostracism. Methylprednisolone use can affect the risk of leprosy re-infection. Case: A 55-year-old female with complaints of abdominal pain, nausea, vomiting, and weakness accompanied by an active leprosy reaction. The patient had a history of leprosy treatment at the Sumenep Health Center in 2000 and at Sumberglagah Leprosy Hospital in 2004, but did not return for an acid-fast bacilli (BTA) check after therapy. She takes methylprednisolone 4 mg once or twice daily to manage an itch or rash. Her dermatological status was a symmetrical leprosy reaction throughout the body, accompanied by erythematous nodules and ulcerated nodules. Smear MH examination results +3 in indirect bacteriology and 25 bacteria in indirect microbiology. Treatment for multibacillary leprosy for 12–18 months and education were planned to increase patient awareness and compliance and appropriate steroid drug use.
{"title":"Morbus Hansen (MH) Reinfection and Inappropriate Methylprednisolone Use","authors":"Wenly Susanto","doi":"10.55175/cdk.v51i8.938","DOIUrl":"https://doi.org/10.55175/cdk.v51i8.938","url":null,"abstract":"Background: Morbus Hansen (MH), or leprosy, is a chronic granulomatous infection caused by Mycobacterium leprae. This disease still has a negative stigma, leading to ostracism. Methylprednisolone use can affect the risk of leprosy re-infection. Case: A 55-year-old female with complaints of abdominal pain, nausea, vomiting, and weakness accompanied by an active leprosy reaction. The patient had a history of leprosy treatment at the Sumenep Health Center in 2000 and at Sumberglagah Leprosy Hospital in 2004, but did not return for an acid-fast bacilli (BTA) check after therapy. She takes methylprednisolone 4 mg once or twice daily to manage an itch or rash. Her dermatological status was a symmetrical leprosy reaction throughout the body, accompanied by erythematous nodules and ulcerated nodules. Smear MH examination results +3 in indirect bacteriology and 25 bacteria in indirect microbiology. Treatment for multibacillary leprosy for 12–18 months and education were planned to increase patient awareness and compliance and appropriate steroid drug use.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"65 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141926859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pneumotoraks katamenial adalah kondisi langka yang termasuk dalam spektrum thoracic endometriosis syndrome (TES), yaitu wanita usia reproduksi mengalami episode pneumotoraks spontan yang terjadi sekitar saat menstruasi. Meskipun jarang, perlu dicurigai pada kasus pneumotoraks berulang disertai riwayat operasi panggul, nyeri haid, dan infertilitas. Diagnosis mencakup anamnesis lengkap, pemeriksaan radiologis, serta video laparoskopi sebagai metode diagnostik definitif. Tata laksana melibatkan manajemen simtomatis drainase pleura, diikuti terapi operatif minimal invasif dan terapi hormonal selama 6-12 bulan setelah manajemen awal. Rekurensi pneumotoraks katamenial tetap menjadi masalah, dan prognosis serta dampaknya belum sepenuhnya dipahami.
{"title":"Pneumotoraks Katamenial: Patofisiologi, Diagnosis, dan Tata Laksana","authors":"Angelina Patricia Chandra, Reynardi Larope Sutanto, Averiell Larope Sutanto","doi":"10.55175/cdk.v51i8.1125","DOIUrl":"https://doi.org/10.55175/cdk.v51i8.1125","url":null,"abstract":"Pneumotoraks katamenial adalah kondisi langka yang termasuk dalam spektrum thoracic endometriosis syndrome (TES), yaitu wanita usia reproduksi mengalami episode pneumotoraks spontan yang terjadi sekitar saat menstruasi. Meskipun jarang, perlu dicurigai pada kasus pneumotoraks berulang disertai riwayat operasi panggul, nyeri haid, dan infertilitas. Diagnosis mencakup anamnesis lengkap, pemeriksaan radiologis, serta video laparoskopi sebagai metode diagnostik definitif. Tata laksana melibatkan manajemen simtomatis drainase pleura, diikuti terapi operatif minimal invasif dan terapi hormonal selama 6-12 bulan setelah manajemen awal. Rekurensi pneumotoraks katamenial tetap menjadi masalah, dan prognosis serta dampaknya belum sepenuhnya dipahami.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"19 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141926012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elvan Wiyarta, Febrilian Kristiawan, Gideon Hot Partogi Sinaga
Latar Belakang: Penggunaan citicoline dikaitkan dengan perbaikan berbagai kondisi neurologis. Artikel ini bertujuan mengeksplorasi potensi citicoline untuk mencegah penurunan fungsi kognitif pasien mild cognitive impairment (MCI). Metode: Penelusuran literatur komprehensif melalui 10 database. Studi yang dipilih harus mencakup pasien dewasa dengan penurunan fungsi kognitif menggunakan citicoline. Seleksi artikel dengan kriteria inklusi dan eksklusi yang ditentukan. Selanjutnya dilakukan telaah kritis dan penilaian level of evidence. Hasil: Dari total 265 studi yang diperoleh, 15 studi dipilih dan dianalisis. Hasil menunjukkan bahwa citicoline memiliki potensi mencegah penurunan fungsi kognitif, baik pada pasien MCI, penyakit Alzheimer, penyakit Parkinson, stroke iskemik, maupun pada orang sehat. Walaupun hasilnya beragam, citicoline secara konsisten signifikan dikaitkan dengan peningkatan skor mini-mental state examination (MMSE) dan uji kognitif lainnya. Simpulan: Citicoline memiliki potensi mencegah penurunan fungsi kognitif pasien MCI. Dibutuhkan lebih banyak penelitian untuk memahami efek jangka panjang dan mekanisme kerja citicoline.
{"title":"Potensi Citicoline dalam Menghambat Penurunan Fungsi Kognitif pada Gangguan Kognitif Ringan","authors":"Elvan Wiyarta, Febrilian Kristiawan, Gideon Hot Partogi Sinaga","doi":"10.55175/cdk.v51i8.1210","DOIUrl":"https://doi.org/10.55175/cdk.v51i8.1210","url":null,"abstract":"Latar Belakang: Penggunaan citicoline dikaitkan dengan perbaikan berbagai kondisi neurologis. Artikel ini bertujuan mengeksplorasi potensi citicoline untuk mencegah penurunan fungsi kognitif pasien mild cognitive impairment (MCI). Metode: Penelusuran literatur komprehensif melalui 10 database. Studi yang dipilih harus mencakup pasien dewasa dengan penurunan fungsi kognitif menggunakan citicoline. Seleksi artikel dengan kriteria inklusi dan eksklusi yang ditentukan. Selanjutnya dilakukan telaah kritis dan penilaian level of evidence. Hasil: Dari total 265 studi yang diperoleh, 15 studi dipilih dan dianalisis. Hasil menunjukkan bahwa citicoline memiliki potensi mencegah penurunan fungsi kognitif, baik pada pasien MCI, penyakit Alzheimer, penyakit Parkinson, stroke iskemik, maupun pada orang sehat. Walaupun hasilnya beragam, citicoline secara konsisten signifikan dikaitkan dengan peningkatan skor mini-mental state examination (MMSE) dan uji kognitif lainnya. Simpulan: Citicoline memiliki potensi mencegah penurunan fungsi kognitif pasien MCI. Dibutuhkan lebih banyak penelitian untuk memahami efek jangka panjang dan mekanisme kerja citicoline.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"23 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141927319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Willy Johan, I. Ayu, N. Saraswati, Karunia Meilani Nurfatika, Dian Angger Suaner, P. Pratiwi, Muhammad Arief Kusuma, Alphonsus Arya Arbikara, Alphonsus Arya
Latar Belakang: Berkaca dari pandemi COVID-19, banyak instalasi gawat darurat (IGD) mengalami kesulitan merespons penyakit menular yang baru muncul dan menimbulkan dampak krisis kesehatan. Penelitian kualitatif ini bermaksud mengeksplorasi manajemen strategi salah satu IGD rumah sakit (RS A) rujukan COVID. Metode: Wawancara mendalam dengan 10 informan kunci, observasi, dan analisis dokumen. Diskusi mendalam dengan para ahli dilakukan untuk menjamin keabsahan data. Hasil: Penelitian menunjukkan bahwa RS A telah mempersiapkan kapasitas cadangan (space, staff, supply, system) sebelum krisis dan sistem penanganan bencana telah dipersiapkan dan terus diperbaharui. Kesimpulan: IGD selain didesain untuk mengoptimalkan pelayanan medis terhadap pasien gawat darurat juga harus dipersiapkan untuk menghadapi keadaan bencana. Kapasitas cadangan yang telah dipersiapkan oleh IGD RS A dalam menghadapi bencana dapat dimanfaatkan sepenuhnya pada pandemi COVID-19.
{"title":"Studi Kualitatif Manajemen Strategi IGD RS A dalam Menghadapi COVID-19 sebagai Input untuk Tata Laksana Ancaman Wabah Penyakit Infeksi","authors":"Willy Johan, I. Ayu, N. Saraswati, Karunia Meilani Nurfatika, Dian Angger Suaner, P. Pratiwi, Muhammad Arief Kusuma, Alphonsus Arya Arbikara, Alphonsus Arya","doi":"10.55175/cdk.v51i8.1193","DOIUrl":"https://doi.org/10.55175/cdk.v51i8.1193","url":null,"abstract":"Latar Belakang: Berkaca dari pandemi COVID-19, banyak instalasi gawat darurat (IGD) mengalami kesulitan merespons penyakit menular yang baru muncul dan menimbulkan dampak krisis kesehatan. Penelitian kualitatif ini bermaksud mengeksplorasi manajemen strategi salah satu IGD rumah sakit (RS A) rujukan COVID. Metode: Wawancara mendalam dengan 10 informan kunci, observasi, dan analisis dokumen. Diskusi mendalam dengan para ahli dilakukan untuk menjamin keabsahan data. Hasil: Penelitian menunjukkan bahwa RS A telah mempersiapkan kapasitas cadangan (space, staff, supply, system) sebelum krisis dan sistem penanganan bencana telah dipersiapkan dan terus diperbaharui. Kesimpulan: IGD selain didesain untuk mengoptimalkan pelayanan medis terhadap pasien gawat darurat juga harus dipersiapkan untuk menghadapi keadaan bencana. Kapasitas cadangan yang telah dipersiapkan oleh IGD RS A dalam menghadapi bencana dapat dimanfaatkan sepenuhnya pada pandemi COVID-19.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"26 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141927117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Necrotizing enterocolitis (NEC) remains one of the most common gastrointestinal diseases in neonates, with high morbidity and mortality. An 8-day-old full-term baby girl was admitted with an initial diagnosis of sepsis and acute diarrhea due to a cow’s milk allergy. Her condition worsened on the 4th day of hospitalization with abdominal distention, bradypnea, and vomiting. An abdominal x-ray showed increased bowel gas. She had a slightly lowered FT4. The findings met Bell’s criteria for the diagnosis of NEC. After being given meropenem and levothyroxine for 7 days, she was discharged on the 12th day of hospitalization in good condition. NEC is allegedly to be a multifactorial disease, with predisposing factors of cow’s milk formula (CMF) feeding or not breast-fed since birth, sepsis, and hypothyroidism. The combination of clinical symptoms, radiologic findings, and risk factor tracing is important in the diagnosis and management of NEC.
坏死性小肠结肠炎（NEC）是新生儿最常见的胃肠道疾病之一，发病率和死亡率都很高。一名 8 天大的足月女婴因牛奶过敏入院，初步诊断为败血症和急性腹泻。住院第 4 天，她的病情恶化，出现腹胀、呼吸困难和呕吐。腹部 X 光片显示肠道气体增多。她的 FT4 稍微降低。这些结果符合贝尔的 NEC 诊断标准。在服用美罗培南和左甲状腺素 7 天后，她于住院第 12 天出院，情况良好。NEC 据称是一种多因素疾病，其诱发因素包括牛奶粉喂养或出生后未进行母乳喂养、败血症和甲状腺功能减退症。结合临床症状、放射学检查结果和危险因素追踪对 NEC 的诊断和治疗非常重要。
{"title":"Necrotizing Enterocolitis, Sepsis, and Diarrhea Due to Cow’s Milk Allergy in A Full-Term Infant with Hypothyroidism","authors":"Runi Arumndari, Asterisa Retno Putri, Claudia Natasha Liman, Putu Siska Suryaningsih","doi":"10.55175/cdk.v51i8.981","DOIUrl":"https://doi.org/10.55175/cdk.v51i8.981","url":null,"abstract":"Necrotizing enterocolitis (NEC) remains one of the most common gastrointestinal diseases in neonates, with high morbidity and mortality. An 8-day-old full-term baby girl was admitted with an initial diagnosis of sepsis and acute diarrhea due to a cow’s milk allergy. Her condition worsened on the 4th day of hospitalization with abdominal distention, bradypnea, and vomiting. An abdominal x-ray showed increased bowel gas. She had a slightly lowered FT4. The findings met Bell’s criteria for the diagnosis of NEC. After being given meropenem and levothyroxine for 7 days, she was discharged on the 12th day of hospitalization in good condition. NEC is allegedly to be a multifactorial disease, with predisposing factors of cow’s milk formula (CMF) feeding or not breast-fed since birth, sepsis, and hypothyroidism. The combination of clinical symptoms, radiologic findings, and risk factor tracing is important in the diagnosis and management of NEC.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"24 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141926992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stroke patients are vulnerable to malnutrition, which is associated with poor outcomes, both in the acute and rehabilitation phases. Malnutrition at admission and one week after admission is a predictor of poor outcomes within or after three months of stroke. Adequate nutritional assessment and management are necessary to improve the outcomes of stroke patients. The CONUT score can be used for nutrition assessment in stroke patients.
{"title":"Use of CONUT Score for Determination of Ischemic Stroke Patients","authors":"Agustiawan, Dewi Novita, Ayu Meilina","doi":"10.55175/cdk.v51i6.1054","DOIUrl":"https://doi.org/10.55175/cdk.v51i6.1054","url":null,"abstract":"Stroke patients are vulnerable to malnutrition, which is associated with poor outcomes, both in the acute and rehabilitation phases. Malnutrition at admission and one week after admission is a predictor of poor outcomes within or after three months of stroke. Adequate nutritional assessment and management are necessary to improve the outcomes of stroke patients. The CONUT score can be used for nutrition assessment in stroke patients.","PeriodicalId":295318,"journal":{"name":"Cermin Dunia Kedokteran","volume":"18 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141379897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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