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Why Do Stem Cells Create Such Public Controversy 干细胞为何引起如此大的公众争议
Pub Date : 2011-09-30 DOI: 10.4245/SPONGE.V5I1.15099
J. Maienschein
Biological development is about history, the history of an individual through time. Historically, the dominant epigenetic tradition has seen the developmental process as an unfolding of potential or in terms of the emergence of new organization that becomes an individual organism over time. The concept of development has included differentiation, growth, and morphogenesis; since the mid-nineteenth century, it has been seen in terms of cell division. Along the way have come explorations of such issues as the extent to which development is driven by hereditary determination rather than flexible regulation in response to changing conditions. Some researchers have focused specifically on examining the capacity for regeneration in response to injury or loss, or on the extent to which parts are self-organizing individually rather than determined segments of a whole. This paper introduces the historical study of development.
生物发育是关于历史的,一个个体的历史。从历史上看,占主导地位的表观遗传传统将发育过程视为潜力的展开,或者是随着时间的推移而成为个体有机体的新组织的出现。发育的概念包括分化、生长和形态发生;从19世纪中期开始,人们就从细胞分裂的角度来看待它。在此过程中,人们开始探索诸如发展在多大程度上是由遗传决定驱动的,而不是为了应对不断变化的条件而进行的灵活调节。一些研究人员专门研究了损伤或损失后的再生能力,或者研究了部分是单独自组织的程度,而不是整体的确定部分。本文介绍了发展的历史研究。
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引用次数: 0
What Are Climate Scientists to Do 气候科学家该怎么做
Pub Date : 2011-09-30 DOI: 10.4245/SPONGE.V5I1.15165
E. Keller
The campaign to discredit predictions of man-made global warming—originally organized by readily identifiable vested interests—has by now recruited a large popular constituency of declared “skeptics” increasingly disposed to “take a stand”: some of them opposed to government regulation in general, some resistant to any claims to intellectual authority (perhaps especially scientific), and some mobilized by a version of the right to individual freedom of opinion. As a result, confidence in the expertise of scientists has reached an all time low: Internet sites, radio talk shows, and television channels preferentially transmit “contrarian” attacks on the credibility of climate scientists. Even our most responsible newspapers and journals, in their very commitment to the traditional ethic of “balance,” sometimes contribute to the widespread misimpression that climate scientists are deeply divided about both the extent of the dangers we face and the relevance of human activity to global warming. Not knowing who or what to believe, the natural response for most people is to do nothing, and the consequence, as Thomas Homer-Dixon wrote last year for the New York Times: “Climate policy is gridlocked, and there’s virtually no chance of a breakthrough” (2010). Meanwhile, as evidence both of the role of human contributions to global warming and the dangers of that warming continues to mount, consensus among climate scientists grows ever stronger, and those of us who attend to that evidence are increasingly alarmed.
这场质疑人为全球变暖预测的运动——最初是由显而易见的既得利益组织起来的——现在已经招募了一大批自称为“怀疑论者”的民众,他们越来越倾向于“表明立场”:他们中的一些人普遍反对政府监管,一些人抵制任何知识权威(也许尤其是科学权威)的主张,还有一些人被一种个人言论自由的权利所动员。结果,人们对科学家专业知识的信心达到了历史最低点:互联网网站、广播谈话节目和电视频道优先传播对气候科学家可信度的“反向”攻击。即使是我们最负责任的报纸和期刊,在他们对传统“平衡”伦理的承诺中,有时也会造成一种普遍的错误印象,即气候科学家在我们面临的危险程度和人类活动与全球变暖的相关性方面存在严重分歧。不知道该相信谁或相信什么,大多数人的自然反应是什么都不做,结果,正如托马斯·荷马-迪克森去年在《纽约时报》上所写的那样:“气候政策陷入僵局,几乎没有突破的机会”(2010)。与此同时,随着人类对全球变暖的影响以及这种变暖的危险性的证据不断增加,气候科学家之间的共识变得越来越强烈,而我们这些关注这些证据的人也越来越感到震惊。
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引用次数: 7
Between Theory and Craft: Exploring the Role of Co-operation within Scientific Research Labs 理论与实践之间:探索合作在科研实验室中的作用
Pub Date : 2011-09-30 DOI: 10.4245/SPONGE.V5I1.14957
B. Lander
This article explores how researchers in a scientific research lab co-operate with each other and value these co-operations, using a case study of a life sciences lab as an illustrative example. It explores how researchers within the lab co-operate in three main ways: through their ideas, methods and resources. A core contention of this article is that the values researchers attach to these different ways of co-operating can be assessed on two dimensions: goals and ways of understanding. The goals dimension moves from group goals, manifested in the vision of the lab defined by its principal investigator, to the goals of individual researchers within the lab, often achieved through work on individual projects. Individual goals were more highly valued by researchers in this case study. The ways of understanding dimension moves from theory-based and theory-building research activities, to craft-based activities related to the research lab’s experiments. Theoretical ways of understanding are more highly valued by researchers in this case study. Combined, these two dimensions mean that researchers will value co-operations that support individual goals and theoretical ways of understanding more highly. Idea-based collaborations, individualistic and theoretical in nature, were the most highly valued. Collaborations based on resources, communal and craft-centered, were the least valued in this case study.
本文以一个生命科学实验室的案例研究为例,探讨了科研实验室的研究人员如何相互合作并重视这些合作。它探讨了实验室内的研究人员如何以三种主要方式进行合作:通过他们的想法、方法和资源。本文的一个核心论点是,研究者赋予这些不同合作方式的价值可以从两个维度来评估:目标和理解方式。目标维度从团队目标(体现在由主要研究者定义的实验室愿景中)移动到实验室中个人研究人员的目标(通常通过个人项目的工作来实现)。在这个案例研究中,研究人员更重视个人目标。对维度的理解方式从以理论为基础、建构理论的研究活动,转向与研究实验室的实验相关的以工艺为基础的活动。在本案例研究中,研究人员更重视理论理解方式。结合起来,这两个维度意味着研究人员将更加重视支持个人目标和理论理解方式的合作。以想法为基础的合作、个人主义和理论性质的合作是最受重视的。在这个案例研究中,基于资源、社区和以工艺为中心的合作是最不受重视的。
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引用次数: 2
Steve Fuller. Science 史蒂夫·富勒。科学
Pub Date : 2011-09-30 DOI: 10.4245/SPONGE.V5I1.14294
Mike Thicke
Historian and philosopher of science Steve Fuller has long embraced his role as a public intellectual. As part of that mission, he testified in the 2005 Dover school board trials, arguing that intelligent design could legitimately claim scientific status. He has since written two books on the intelligent design controversy. Science, his latest effort, is part of The Art of Living series. It is ostensibly an exploration of what it means to “live scientifically,” but is more accurately described as an argument for the necessary connection between science and theology. Fuller’s central argument should be no surprise to those familiar with his previous commentary on intelligent design. It is a two-pronged pragmatic argument. On the one hand, Darwinism is dispensable: most work in biology does not rely on Darwin’s theory of evolution (think molecular biology). On the other hand, religion is indispensable for scientific progress: without believing that the universe has been designed to be intelligible to humans, there is no motivation for scientists to attempt to comprehend it. However, in Science Fuller goes further than this. He also claims that a designer with intelligence resembling our own is the best explanation for the success of science.
历史学家和科学哲学家史蒂夫·富勒(Steve Fuller)长期以来一直接受自己作为公共知识分子的角色。作为这一使命的一部分,他在2005年多佛学校董事会的审判中作证,认为智能设计可以合法地主张科学地位。此后,他写了两本关于智能设计争议的书。他的最新作品《科学》是《生活的艺术》系列的一部分。它表面上是对“科学地生活”的探索,但更准确地说,它是对科学与神学之间必要联系的论证。对于那些熟悉富勒之前关于智能设计的评论的人来说,他的中心论点应该不足为奇。这是一个双管齐下的务实论点。一方面,达尔文主义是可有可无的:生物学的大多数工作并不依赖于达尔文的进化论(想想分子生物学)。另一方面,宗教对科学进步是不可或缺的:如果不相信宇宙是被设计成人类可以理解的,科学家就没有动力去试图理解它。然而,在《科学》中,富勒走得更远。他还声称,一个拥有与人类相似智力的设计师是科学成功的最好解释。
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引用次数: 0
The Relevance of Scientific Practice to the Problem of Coordination 科学实践与协调问题的相关性
Pub Date : 2011-09-30 DOI: 10.4245/SPONGE.V5I1.14607
Andrew Peterson
In his early work on the problem of coordination, Hans Reichenbach introduced axioms of coordination to describe the relationship between theory and observation. His insistence that these axioms are determinable a priori, however, causes him to ignore the normative dimensions of scientific inquiry and, in turn, generates a misleading interpretation of the theory-observation relationship. In response, I propose an alternative approach that describes this relationship through the framework of scientific practices. My argument will draw on two examples that have not been explored by the philosophical literature in the context of coordination problems: the clinical definition of death and Stanley Prusiner’s prion hypothesis.
汉斯·莱辛巴赫(Hans Reichenbach)在研究协调问题的早期工作中,引入了协调公理来描述理论与观测之间的关系。然而,他坚持认为这些公理是先天可决定的,这导致他忽视了科学探究的规范维度,反过来又产生了对理论-观察关系的误导性解释。作为回应,我提出了另一种方法,通过科学实践的框架来描述这种关系。我的论点将借鉴哲学文献在协调问题的背景下没有探讨过的两个例子:死亡的临床定义和斯坦利·普鲁西纳的朊病毒假说。
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引用次数: 1
Periodicals and Controversy 期刊与争议
Pub Date : 2011-09-30 DOI: 10.4245/SPONGE.V5I1.15324
B. Lightman
In 1854 the biologist Thomas Henry Huxley pointed to a significant change in the way that reviewers were treating books that endorsed deeply flawed scientific theories. In the past, “when a book had been shown to be a mass of pretentious nonsense,” it “quietly sunk into its proper limbo. But these days appear, unhappily, to have gone by.” Due to the “utter ignorance of the public mind as to the methods of science and the criterion of truth,” scientists were now forced to review such books in order to expose their deficiencies (Huxley 1903, 1). Huxley’s observation indicates how the development of a mass reading audience in mid-nineteenth century Britain transformed the very nature of scientific controversy. Scientists were compelled to debate the validity of theories in new public sites, not just in exclusive scientific societies or in specialized scientific journals with limited circulation. It was during the nineteenth century that public controversy—not limited to science alone—became possible for the first time. In this short piece I will discuss how the “communications revolution” produced a public space for the debate over evolutionary theory in mid-nineteenth century Britain. I will focus on periodicals as one of those public spaces in which the debate took place.1 As Huxley found, attempting to resolve a scientific controversy in the general periodical press could be a risky venture. Although a non-specialized journal could provide the public space necessary for reaching the reading audience, maintaining scientific authority in such a site was somewhat problematic.
1854年,生物学家托马斯·亨利·赫胥黎(Thomas Henry Huxley)指出,评论家对待那些支持存在严重缺陷的科学理论的书籍的方式发生了重大变化。在过去,“当一本书被证明是一堆自命不凡的废话时”,它“就会悄悄地陷入应有的困境”。但不幸的是,这些日子似乎已经过去了。”由于“公众对科学方法和真理标准的完全无知”,科学家们现在被迫审查这些书籍,以揭露它们的缺陷(赫胥黎1903,1)。赫胥黎的观察表明,19世纪中期英国大量读者的发展如何改变了科学争议的本质。科学家们被迫在新的公共场所辩论理论的有效性,而不仅仅是在专门的科学协会或发行量有限的专业科学期刊上。正是在19世纪,公众争论——不仅限于科学领域——第一次成为可能。在这篇短文中,我将讨论“通信革命”如何在19世纪中期的英国为进化论的辩论创造了一个公共空间。我将把重点放在期刊上,作为辩论发生的公共空间之一正如赫胥黎发现的那样,试图在普通期刊媒体上解决科学争议可能是一项冒险的冒险。尽管非专业期刊可以提供接触读者所需的公共空间,但在这样一个网站上维护科学权威有些问题。
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引用次数: 3
Latour's greatest hits, reassembled: Review of Bruno Latour's Reassembling the social: An introduction to Actor-Network-Theory 拉图尔的代表作,重组:布鲁诺·拉图尔的《重组社会:行为者网络理论导论》书评
Pub Date : 2011-09-30 DOI: 10.4245/SPONGE.V5I1.14968
Nicholas J. Rowland, Jan-H. Passoth, Alexander B. Kinney
It seems peculiar that a non-theory, anti-method has managed to become canonical, but that is what Bruno Latour will introduce you to in his book; the post-pluralist, post-humanist attitude called Actor-Network-Theory (ANT). Drawing together heaps of controversial research, Latour resuscitates ANT after its 1999 death (see Law and Hassard 1999). Like Graham Harman’s book about Latour, The Prince of Networks (2009), Reassembling the Social is the outcome of various lectures and seminars, and must be read as such. Readers looking for the second incarnation of Science in Action (1987) or a follow-up to The Pasteurization of France (1988) will be sorely disappointed because Latour’s offering here is more akin to Politics of Nature (2004) or We Have Never Been Modern (1993) in that the audience gets a repetitive synthesis peppered with apercu rather than reams of deep empirical analysis, as Gubert (2007, 603) has also suggested. Conceivably, the book might be the classroom workhorse for Latour’s new transnational teaching and research project “Mapping Controversies,” which is running simultaneously in six institutions (see http://www.demoscience.org/).
一种非理论、反方法的理论成为了规范,这似乎很奇怪,但布鲁诺·拉图尔将在他的书中向你们介绍这一点;后多元主义、后人文主义的态度被称为行动者网络理论(ANT)。拉图尔汇集了大量有争议的研究成果,使1999年倒闭的ANT公司起死回生(见Law and Hassard 1999)。就像格雷厄姆·哈曼关于拉图尔的书《网络王子》(2009)一样,《重组社会》是各种讲座和研讨会的成果,必须这样读。寻找《行动中的科学》(1987)或《法国的巴氏灭菌》(1988)的续集的读者将会非常失望,因为拉图尔在这里提供的内容更类似于《自然的政治》(2004)或《我们从未现代》(1993),因为观众得到的是一种重复的综合,其中充斥着apercu,而不是像古伯特(2007,603)所建议的那样,大量深入的实证分析。可以想象,这本书可能会成为拉图尔新的跨国教学和研究项目“测绘争议”的课堂教材,该项目正在六个机构同时开展(见http://www.demoscience.org/)。
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引用次数: 8
Scientific Instruments: Knowledge, Practice, and Culture [Editor’s Introduction] 科学仪器:知识、实践与文化[编者简介]
Pub Date : 2010-08-30 DOI: 10.4245/SPONGE.V4I1.14231
Isaac Record
To one side of the wide third-floor hallway of Victoria College, just outside the offices of the Institute for the History and Philosophy of Science and Technology, lies the massive carcass of a 1960s-era electron microscope. Its burnished steel carapace has lost its gleam, but the instrument is still impressive for its bulk and spare design: binocular viewing glasses, beam control panel, specimen tray, and a broad work surface. Edges are worn, desiccated tape still feebly holds instructive reminders near control dials; this was once a workhorse in some lab. But it exists now out of time and place; like many of the scientific instruments we study, it has not been touched by knowing hands in decades.
维多利亚学院(Victoria College)宽阔的三楼走廊的一侧,就在科学技术历史与哲学研究所(Institute for the History and Philosophy of Science and Technology)办公室的外面,躺着一台上世纪60年代电子显微镜的巨大残骸。它的抛光钢外壳已经失去了光泽,但它的体积和简洁的设计仍然给人留下了深刻的印象:双目观察镜、光束控制面板、标本托盘和宽阔的工作台面。边缘已经磨损,干燥的胶带仍然无力地在控制表盘附近贴着指导性的提醒;这曾经是某个实验室的主力设备。但它现在存在于时间和地点之外;像我们研究的许多科学仪器一样,它已经几十年没有人碰过了。
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引用次数: 2
The Challenge of Authenticating Scientific Objects in Museum Collections: Exposing the Forgery of a Moroccan Astrolabe Allegedly Dated 1845 CE 鉴定博物馆藏品中的科学物品的挑战:揭露伪造的摩洛哥星盘,据称是1845年的
Pub Date : 2010-08-30 DOI: 10.4245/sponge.v4i1.13025
Ingrid Hehmeyer
The astrolabe is an instrument designed to measure the altitude of celestial bodies in order to tell time by day or by night. An astrolabe in the Royal Ontario Museum’s collections was acquired at auction in 1988. According to the auction catalogue, it was made in Morocco, dated 1845. Years later, in preparation for a university course on the history of science, this writer’s scrutiny of the astrolabe’s inscribed features and physical condition suggested that it was a forgery. The paper explains the reasoning behind the judgement of falsehood.
星盘是一种用来测量天体高度的仪器,用来判断白天或晚上的时间。1988年,皇家安大略博物馆(Royal Ontario Museum)在拍卖会上获得了一个星盘。根据拍卖目录,它是1845年在摩洛哥制造的。多年以后,在准备一门大学科学史课程时,笔者仔细研究了星盘上的铭刻特征和物理状况,发现这是一件赝品。本文解释了虚假判断背后的推理。
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引用次数: 0
Out the Door: A Short History of the University of Toronto Collection of Historical Scientific Instruments 出了门:多伦多大学历史科学仪器收藏简史
Pub Date : 2010-08-30 DOI: 10.4245/sponge.v4i1.13802
Erich Weidenhammer, Michael da Silva
Since the late 1970s, various attempts have been made to organize the scientific instruments used in research carried out at the University of Toronto into a catalogued, protected, and accessible collection. Unlike other major research universities with which Toronto compares itself, such as Harvard, Yale, Oxford and Cambridge, to name only a few, these efforts have not been successful. The failure to implement even a modest campus-wide program to safeguard the university's material heritage has had unfortunate consequences. Nevertheless, a great deal of material survives. In the following paper, we examine the circumstances of the historical instruments at the University of Toronto. We argue that this university's scientific instruments are an essential piece of its identity and history. Finally, we propose a practical bottom up approach through which the current collection can be stabilized and secured (with new instruments added) so that future students can reflect on today's research with the benefit of a rich and well-documented collection.
自20世纪70年代末以来,人们进行了各种尝试,将多伦多大学研究中使用的科学仪器整理成一个编目、保护和可访问的收藏。与多伦多与之比较的其他主要研究型大学不同,如哈佛、耶鲁、牛津和剑桥,仅举几例,这些努力并不成功。未能在全校范围内实施哪怕是一个适度的保护大学物质遗产的计划,已经产生了不幸的后果。然而,大量的材料留存了下来。在下面的文章中,我们考察了多伦多大学历史仪器的情况。我们认为,这所大学的科学仪器是其身份和历史的重要组成部分。最后,我们提出了一种实用的自下而上的方法,通过这种方法可以稳定和保护当前的收藏(添加新仪器),以便未来的学生可以利用丰富且记录良好的收藏来反思今天的研究。
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引用次数: 0
期刊
Spontaneous Generations-Journal for the History and Philosophy of Science
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