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Modulate the Effects of the Bone Marrow–Derived Mesenchymal Stem Cells’ Supernatant on Neutrophil Functions by 17-beta Estradiol 17-雌二醇调节骨髓间充质干细胞上清液对中性粒细胞功能的影响
Pub Date : 2015-07-15 DOI: 10.18869/ACADPUB.HMS.21.2.91
N. A. ahangran, zahra nekoeei, norouz delirajh
Article Type Original Research Authors Nekoeii Z.1 BSc, Afzal Ahangran N.* PhD, Delirejh N.1 PhD How to cite this article Nekoeii Z, Afzal Ahangran N, Delirejh N. Modulate the Effects of the Bone Marrow–Derived Mesenchymal Stem Cells’ Supernatant on Neutrophil Functions by 17-beta Estradiol. Quarterly of the Horizon of Medical Sciences. 2015;21(2):91-96.
文章类型主要作者:张晓明,张晓明,张晓明,张晓明。17- β雌二醇对骨髓间充质干细胞上清液对中性粒细胞功能的影响。医学杂志,2015;21(2):91-96。
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引用次数: 0
Effect of High-Intensity Interval Training (HIT) for 4 Weeks with and without L-Arginine Supplementation on the Performance of Women’s Futsal Players 高强度间歇训练(HIT) 4周加或不加l -精氨酸对女子五人制足球运动员表现的影响
Pub Date : 2015-07-15 DOI: 10.18869/ACADPUB.HMS.21.2.113
A. Hoseini, V. V. Dehnou, M. Azizi, Mahin Alam
Aims: In recent years, consumption of nutrition supplements such as LArginine has increased in athletes in order to increase efficiency and reduce fatigue. The purpose of the present study was to examine the effects of 4 weeks of high-intensity interval training (HIT) with and without L-Arginine supplementation on anaerobic and aerobic performance in women’s futsal players. Materials & Methods: In this research study (2013), 20 healthy women futsal players in Kermanshah City, Iran, were selected by available sampling method. Subjects were randomly divided into two groups; training-supplement (n=10) and training-placebo (n=10). Both groups, in addition to futsal specific training, performed RAST (anaerobic sprint test) test as high-intensity interval training protocol, 2 sessions per week for 4 weeks. Before and after the training protocol, subjects performed Bruce and RAST tests in order to measure aerobic and anaerobic power, respectively. Blood samples were collected 30 seconds after the RAST test to measure the levels of serum lactate concentration. All data were analyzed using independent T and paired T tests. Findings: After the training, both groups showed significant increasing in VO2max and anaerobic power (p<0.05) and significant decreasing in blood lactate concentrations (p<0.05); percentage of changes were greater for the first than the second group in all three factors. Conclusion: Using high-intensity interval training in combination with LArginine lead to improvement of aerobic and anaerobic fitness in women futsal players.
目的:近年来,为了提高效率和减少疲劳,运动员对营养补充剂如精氨酸的消耗有所增加。本研究的目的是研究4周的高强度间歇训练(HIT)在补充和不补充l -精氨酸的情况下对女子五人制足球运动员无氧和有氧表现的影响。材料与方法:本研究(2013)采用有效抽样方法,选取伊朗Kermanshah市20名健康女子五人制足球运动员。受试者随机分为两组;训练补充组(n=10)和训练安慰剂组(n=10)。两组在五人制专项训练的基础上,进行RAST(无氧冲刺测试)测试作为高强度间歇训练方案,每周2次,持续4周。在训练方案之前和之后,受试者分别进行Bruce和RAST测试,以测量有氧和无氧能力。RAST试验后30秒采集血样,测定血清乳酸浓度水平。所有数据均采用独立T检验和配对T检验进行分析。结果:两组训练后最大摄氧量和无氧能力均显著提高(p<0.05),血乳酸浓度显著降低(p<0.05);在所有三个因素中,第一组的变化百分比大于第二组。结论:高强度间歇训练联合精氨酸可提高女子五人制足球运动员的有氧和无氧体能。
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引用次数: 3
EFFECTS OF 6 WEEKS RESISTANCE TRAINING ON BODY COMPOSITION, SERUM LEPTIN AND MUSCLE STRENGTH IN NON-ATHLETIC MEN 6周抗阻训练对非运动男性身体成分、血清瘦素和肌肉力量的影响
Pub Date : 2015-07-15 DOI: 10.18869/ACADPUB.HMS.21.2.135
KHalilolah Monikh, M. Kashef, A. Azad, A. Ghasemnian
Aims: Leptin is a polypeptide that is correlated with body weight changes and energy consumption and affected by exercise training. The aim of the present study was to determine the effect of 6 weeks resistance training on body composition, serum leptin and muscle strength in non-athletic men. Materials & Methods: In this semi-experimental trial, 22 non-athletes male living in dormitory of Zanjan University, who were enrolled in 2011-12 academic year were selected with purposive sampling method and randomly assigned to experimental (n=12) and control (n=10) groups. The experimental group performed training program based on the protocol of Kramer and Ratns for 6 weeks (3 sessions per week). At the beginning and end of the research, muscle strength, body composition and serum leptin were measured. Serum leptin was measured by ELISA. Independent T and paired T tests were used to analysis the data in SPSS 16 software. Findings: After 6 weeks of strength training, changes in serum leptin levels and body composition (fat mass without fat) between the two groups was not statistically significant (p>0.05). But in experimental group, the upper and lower body strength training was significantly increased compared with pretest in control group (p<0.05). Conclusion: It seems that no significant changing in serum leptin levels after a period of resistance training is due to no changing in body fat and not enough exercise, but this training cause in increasing muscle strength.
目的:瘦素是一种与体重变化和能量消耗相关的多肽,受运动训练的影响。本研究的目的是确定6周阻力训练对非运动男性身体成分、血清瘦素和肌肉力量的影响。材料与方法:采用有目的抽样方法,选取2011-12学年赞詹大学宿舍非运动员男性学生22名,随机分为实验组(n=12)和对照组(n=10)。实验组按照Kramer和Ratns的训练方案进行训练,为期6周(每周3次)。在研究开始和结束时,测量了肌肉力量、身体成分和血清瘦素。ELISA法测定血清瘦素水平。采用SPSS 16软件进行独立T检验和配对T检验。结果:经过6周的力量训练后,两组血清瘦素水平和体成分(不含脂肪的脂肪量)变化无统计学意义(p>0.05)。但试验组上半身和下半身力量训练较对照组前显著增加(p<0.05)。结论:一段时间的抗阻训练后血清瘦素水平没有明显变化似乎是由于体脂没有变化和运动量不够,但这种训练导致肌肉力量增加。
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引用次数: 10
Effect of Ziziphus jujuba Supplementation before One Session of Acute Resistance Exercise on the Serum Glutathione Peroxidase and Superoxide Dismutase Activity 急性抵抗运动前补充酸枣对血清谷胱甘肽过氧化物酶和超氧化物歧化酶活性的影响
Pub Date : 2015-07-15 DOI: 10.18869/ACADPUB.HMS.21.2.97
M. Afzalpour, Hosein Abtahi Eivari, A. Rezazadeh, Amin Soluki
Aims: Intense exercise damages tissues and disturb some cellular processes through oxidative stress and antioxidants can modulate intense exerciseinduced oxidative stress. The aim of the present study was to examine the effect of Ziziphus jujube supplements on the glutathione peroxidase (GPX) and superoxide dismutase (SOD) activity in serum after a single session of resistance training. Materials & Methods: In this semi-experimental study, 24 young non-athletes females were purposefully selected and were randomly divided into two groups; Ziziphus jujube consumption+intensive resistance exercise and intensive resistance exercise. The first group received 0.4g/kg of body weight of Ziziphus jujube daily for 3 weeks, but another group prohibited from Ziziphus jujube consumption. Both groups carried out a session of intensive resistance exercise consisting of 5 movements at 90% of one maximum repetition. Blood samples were measured in three phases; baseline, after 3 weeks of the Ziziphus jujube consumption, and after the resistance exercise session. In order to valuation the enzymes activity the enzymatic method was used. Data were analyzed by the repeated measures ANOVA and LSD tests in SPSS 22 software. Findings: The Ziziphus jujube supplement significantly increased GPX activity (p=0.001) but it had no significant (p=0.19) influence on SOD activity. In addition, intensive resistance training significantly decreased the SOD (p=0.03) and GPX (p=0.02) activity immediately after exercise. Conclusion: Using Ziziphus jujube supplements improves the antioxidant enzyme activity of GPX, but this improvement is not likely enough to inhibit the depression of the antioxidant status after performing resistance exercise.
目的:高强度运动通过氧化应激破坏组织,扰乱细胞的某些过程,抗氧化剂可以调节高强度运动引起的氧化应激。本研究的目的是研究补品酸枣对单次抗阻训练后血清谷胱甘肽过氧化物酶(GPX)和超氧化物歧化酶(SOD)活性的影响。材料与方法:在半实验研究中,有目的地选取24名年轻的非运动员女性,随机分为两组;酸枣消费+强化抗阻运动+强化抗阻运动。第一组每天给予0.4g/kg体重的红枣,连续3周,另一组禁止食用红枣。两组都进行了一次高强度的阻力训练,包括5个动作,每次最多重复90%。血液样本分三个阶段测量;基线,食用3周后的酸枣,并在阻力运动后。为了评价酶的活性,采用了酶法。采用SPSS 22软件进行重复测量方差分析和LSD检验。结果:补充酸枣显著提高GPX活性(p=0.001),但对SOD活性无显著影响(p=0.19)。此外,高强度阻力训练显著降低运动后SOD (p=0.03)和GPX (p=0.02)活性。结论:补充酸枣可提高GPX抗氧化酶活性,但不足以抑制抗阻运动后抗氧化能力的下降。
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引用次数: 5
Effect of Aqueous and Methanolic Extracts of Momordica charantia Fruit on Blood Glucose and Liver Enzymes in Diabetic Rats 苦瓜水、醇提取物对糖尿病大鼠血糖及肝酶的影响
Pub Date : 2015-07-15 DOI: 10.18869/ACADPUB.HMS.21.2.105
Hamideh Kermany, K. Shahanipour, A. Nakhaee
Aims: Karela (Momordica charantia), is extensively used in traditional medicine as an antidiabetic drug. The aim of the present study was to analyze the effect of aqueous and methanolic extrarct of Momordica charantia on blood glucose and liver enzymes of rats. Materials & Methods: In this experimental study, 36 adult male Wistar rats were divided into 6 groups (6 rats in each group); control (healthy rats), negative control (diabetic rats by Streptozotocine) and 4 experimental groups (diabetic rats which recived aqueous and methanolic extracts of plant in concentrations of 50 and 100mg/kg of body weight daily for 40 days). The amount of the blood glucose was determined by sequential incision of the tip of the tail once a weak. After completing 40 days, blood was collected from heart of rats and the level of the liver enzymes serum was determined. The results were analysed by ANOVA with repeated measure and one way ANOVA tests in SPSS 19 software. Findings: The effect of different concentrations of aqueous and methanolic extracts on the blood glucose level was significant (p<0.001). Also a significant difference was observed between the amount of the aspartate aminotransfrase (p=0.049) and alanin aminotransfrase (p=0.005) enzymes activity at the two groups of negative control and 50mg/kg of body weight of methanolic extract. Using of 50 and 100mg/kg of body weight of aqueous and methanolic extracts reduced the alkalin phosphatase enzyme activity (p=0.002). Conclusion: Aqueous extract of Momordica charantia fruit have better effect on reducing the blood glucose than methanolic extracts. Both aqueous and methanolic extracts reduce the activity of aspartate aminotransfrase, alanin aminotransfrase and alkalin phosphatase.
目的:Karela (Momordica charantia)作为一种抗糖尿病药物在传统医学中被广泛使用。研究苦瓜水提液和甲醇提液对大鼠血糖和肝酶的影响。材料与方法:将36只成年雄性Wistar大鼠分为6组,每组6只;对照组(健康大鼠)、阴性对照组(链脲佐菌素诱导的糖尿病大鼠)和4个实验组(糖尿病大鼠,每天分别给予浓度为50和100mg/kg体重的植物水提液和甲醇提液,连续40 d)。血糖量测定是通过连续一次的尾尖切口来测定的。40 d后,取大鼠心脏采血,测定血清肝酶水平。采用SPSS 19软件进行重复测量和单因素方差分析。结果:不同浓度的水提物和甲醇提物对血糖水平的影响显著(p<0.001)。阴性对照组和50mg/kg体重甲醇提取物组的天冬氨酸转氨酶(p=0.049)和丙氨酸转氨酶(p=0.005)活性也有显著差异。使用50和100mg/kg体重的水提物和甲醇提物降低了碱磷酸酶活性(p=0.002)。结论:苦瓜水提物降血糖效果优于甲醇提物。水提液和甲醇提液均可降低天冬氨酸转氨酶、丙氨酸转氨酶和碱性磷酸酶的活性。
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引用次数: 2
MODIFIABLE RISK FACTORS ON PRETERM BIRTH: A CASE-CONTROL STUDY 可改变的早产危险因素:一项病例对照研究
Pub Date : 2015-07-15 DOI: 10.18869/ACADPUB.HMS.21.2.141
M. Eshghizadeh, M. Moshki, Z. Majeedi, M. Abdollahi
,
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引用次数: 4
Effect of Muscle Relaxation on Hemodialysis Patients’ Pain 肌肉松弛对血液透析患者疼痛的影响
Pub Date : 2015-07-15 DOI: 10.18869/ACADPUB.HMS.21.2.75
T. B. Beydokhti, M. Kianmehr, Jahanshir Tavakolizadeh, M. Moghadam, F. Biabani
Aims: Dialysis patients have experienced some degree of pain, especially foot pain. Some complementary interventions such as muscle relaxation are effective in relieving pain. This study was performed with the aim of assessing the effect of muscle relaxation on hemodialysis patients’ pain. Materials & Methods: This randomized controlled clinical trial was conducted on 90 hemodialysis patients of Khatamolanbia and Imam Ali hemodialysis centers of Zahedan during 2013 and 2014. The patients were chosen by purposive sampling based on inclusion criteria and randomly divided into control and experimental groups. Pain intensity was measured by McGill questionnaire before intervention. Then, Benson muscle relaxation was taught to patients’ of case group and was performed by them for 15-20 minutes twice a day for a month. The control group received no training. The pain intensity of two groups was compared after one month. The data were analyzed using Chisquare, independent T and Mann-Whitney tests by SPSS 21 software. Findings: Most of the patients were men, married, housekeeper with under diploma education and the mean age of them was 43.0±15.0 years. There was a significant decrease in pain intensity in the intervention group compared to the control (p=0.03). Conclusion: The muscle relaxation technique can be employed to reduce pain in hemodialysis patients.
目的:透析患者都经历过一定程度的疼痛,尤其是足部疼痛。一些辅助干预措施,如肌肉放松,对缓解疼痛是有效的。本研究的目的是评估肌肉放松对血液透析患者疼痛的影响。材料与方法:本随机对照临床试验选取2013 - 2014年在扎黑丹Khatamolanbia和Imam Ali血液透析中心就诊的90例血液透析患者为研究对象。根据纳入标准进行有目的抽样,随机分为对照组和实验组。干预前采用McGill问卷测量疼痛强度。然后对病例组患者进行Benson肌肉放松训练,每天2次,每次15-20分钟,持续1个月。对照组不接受任何训练。1个月后比较两组疼痛强度。采用SPSS 21软件,采用Chisquare、独立T检验和Mann-Whitney检验对数据进行分析。结果:患者以男性居多,已婚,管家,大专以下学历,平均年龄43.0±15.0岁。与对照组相比,干预组疼痛强度明显降低(p=0.03)。结论:肌肉放松技术可以减轻血液透析患者的疼痛。
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引用次数: 9
Effect of Aerobic Training for 8 Weeks on C-Reactive Protein, Uric Acid and Total Bilirubin in Sedentary Elderly Women 有氧训练8周对久坐老年妇女c反应蛋白、尿酸和总胆红素的影响
Pub Date : 2015-07-15 DOI: 10.18869/ACADPUB.HMS.21.2.81
M. G. Moghadam, K. Hejazi
Aims: Increased levels of CRP, uric acid and total bilirubin increase the risk of coronary artery disease. The aim of this study was to investigate the effects of selected aerobic training on CRP, uric acid and total bilirubin in sedentary elderly women. Materials & Methods: In this semi-experimental study, in 2014, which was done in Mashhad, 21 sedentary and healthy women with range of 60-70 years old were selected using available and purposive sampling method. They were randomly divided into two groups; experimental (n=11) and control (n=10). The 8 weeks of aerobic training (3 times a week, 45-60 minutes per session, with intensity of 50-70 percent of reserve heart rate) were performed. Blood samples were taken at baseline and at the end of the study. Data were analyzed using paired and independent T tests in SPSS 20 software. Findings: Body weight (p=0.001), BMI (p=0.01), body fat percent (p=0.02), CRP levels (p=0.01) and uric acid (p=0.001) were decreased at the end of training compared with the beginning of aerobic training significantly in the experimental group. Moreover, a significant difference was observed between experimental and control groups according to weight (p<0.05). Conclusion: The aerobic training has positive effects on the new biomarker of cardiovascular indicators and aerobic training can prevent the incidence of atherosclerosis diseases.
目的:CRP、尿酸和总胆红素水平升高会增加冠状动脉疾病的风险。本研究的目的是研究选择性有氧训练对久坐的老年妇女CRP、尿酸和总胆红素的影响。材料与方法:本半实验研究于2014年在马什哈德(Mashhad)进行,采用有效且有目的的抽样方法,选取了21名年龄在60-70岁之间的久坐健康女性。他们被随机分为两组;实验组(n=11)和对照组(n=10)。进行了8周的有氧训练(每周三次,每次45-60分钟,强度为储备心率的50- 70%)。在研究开始时和研究结束时采集血样。数据在SPSS 20软件中采用配对T检验和独立T检验进行分析。结果:实验组在训练结束时体重(p=0.001)、BMI (p=0.01)、体脂率(p=0.02)、CRP水平(p=0.01)、尿酸(p=0.001)均较有氧训练开始时显著降低。按体重计,试验组与对照组差异有统计学意义(p<0.05)。结论:有氧训练对心血管新标志物指标有积极影响,有氧训练可预防动脉粥样硬化疾病的发生。
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引用次数: 13
EFFECT OF CORIANDER FRUIT ON CLINICAL COURSE OF MIGRAINE PATIENTS: A COMPARISON BETWEEN RANDOM EFFECT AND TRANSITION MODELS 香菜果对偏头痛患者临床病程的影响:随机效应与过渡模型的比较
Pub Date : 2015-07-10 DOI: 10.18869/ACADPUB.HMS.21.2.129
Anita Mansouri, F. Zayeri, A. Baghestani, Zahra Ghorbanifar, H. D. Kasmaei, Ali Sheidaei
Article Type Original Research Authors Mansouri A.1 MSc, Zayeri F.* PhD, Baghestani A.R.1 PhD, Ghorbanifar Z.2 PhD, Delavar Kasmaei H.3 PhD, Sheidaei A.1 MSc How to cite this article Mansouri A, Zayeri F, Baghestani A.R, Ghorbanifar Z, Delavar Kasmaei H, Sheidaei A. Effect of Coriander Fruit on Clinical Course of Migraine Patients: A Comparison between Random Effect and Transition Models. Quarterly of the Horizon of Medical Sciences. 2015;21(2):129-134.
文章类型主要作者:Mansouri A.1 MSc, Zayeri F.* PhD, Baghestani A.R.1Mansouri A, Zayeri F, Baghestani A. r, Ghorbanifar Z, Delavar Kasmaei H, Sheidaei A.香菜果对偏头痛患者临床病程的影响:随机效应和过渡模型的比较。医学杂志。2015;21(2):129-134。
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引用次数: 3
ANALGESIC AND ANTI-INFLAMMATORY EFFECTS OF HYDROALCOHOLIC EXTRACT OF SALVIA MULTICAULIS ON MALE RATS 鼠尾草水醇提取物对雄性大鼠的镇痛和抗炎作用
Pub Date : 2015-07-10 DOI: 10.18869/ACADPUB.HMS.21.2.121
A. Abdolmaleki, M. Fereidoni, B. F. Moghadam, A. Asgari
Aims: One of the most basic methods for coping with diseases and pain relief had been the use of medicinal plants. The aim of this study was to the determination of analgesic and anti-inflammatory effects of Salvia multicaulis hydroalcoholic extract. Materials & Methods: In this experimental study, 42 male Wistar rats were divided in 6 groups (n=7); the control (receive nothing), the sham (receive solvent intraperitoneally) and 4 groups that received plant extract at the doses of 50, 100, 200 and 400mg/kg intraperitoneally. Tail flick and formalin test were used for evaluation of thermal and chemical pain, also for assessment the degree of inflammation, rat paw edema volume was acquired by plethysmometric test. Data were analyzed in SPSS 16 software by ANOVA with repeated measuring and T student tests. Findings: The intraperitoneally injection of extract in all doses decreased the chemical pain induced by formalin (p<0.05). Hydroalcoholic extract of plant at doses 200 and 400mg/kg caused hyperalgesia in compared with control group (p<0.01). All concentrations of hydroalcoholic extract of plant decreased the inflammation (p<0.01). Conclusion: Intraperitoneally administration of hydroalcoholic extract of Salvia multicaulis has analgesic effects.
目的:药用植物是治疗疾病和缓解疼痛的最基本方法之一。本研究的目的是测定丹参水醇提取物的镇痛和抗炎作用。材料与方法:将42只雄性Wistar大鼠分为6组(n=7);对照组(不注射)、假手术组(腹腔注射溶剂)和4组分别腹腔注射剂量为50、100、200、400mg/kg的植物提取物。用甩尾法和福尔马林法评价热痛、化学痛和炎症程度,用体积计法测定大鼠足部水肿量。数据在SPSS 16软件中进行方差分析,采用重复测量和T学生检验。结果:腹腔注射各剂量提取物均能减轻福尔马林所致的化学疼痛(p<0.05)。200和400mg/kg剂量的植物水酒精提取物引起痛感过敏(p<0.01)。各浓度植物水酒精提取物均能降低炎症反应(p<0.01)。结论:丹参水醇提取物腹腔注射具有镇痛作用。
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引用次数: 5
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The Horizon of Medical Sciences
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