Pub Date : 2016-01-10DOI: 10.18869/ACADPUB.HMS.22.1.21
سیدرضا عطارزاده حسینی, امیر رشیدلمیر, محسن دهباشی
Aims: Nowadays, using the derivatives of steroids has been increased among athletes, despite their vast gradient side effects. The aim of this study was to compare the effects of 17α-alkyl steroids and 17β-hydroxy steroids on levels of liver enzymes and hematological factors in male bodybuilders. Materials & Methods: In this causal comparing study in 2014, 24 male bodybuilders of Mashhad City, Iran, were entered to the study by census method. The samples were divided into three groups (each 8 persons); consumers of oral steroids (17α-alkyl), consumers of injected steroids (17βhydroxy) and athletes without the experience of using steroids. The blood samples from cubital vein for measurements of the liver enzymes and hematological factors were taken 48 hours after training following 12 hours of overnight fasting. Data were analyzed using ANOVA in SPSS 19 software. Findings: The level of ALT and AST enzymes in the first group were increased over the second (p=0.032) and third (p=0.001) groups significantly. The amount of red blood cells were significantly higher in second group then first and third groups and in first group than control group (p=0.01). The levels of hematocrit and hemoglobin in the first and second groups significantly were higher than third group (p=0.01). However, there were no significant differences in values of lymphocytes, Neutrophils, ALP, MCV, MCH, MCHC, WBC and PLT between the groups. Conclusion: AST and ALT enzymes merely increase by taking oral steroids (17α-alkyl); however, increase in erythrocyte, hematocrit and hemoglobin are expected by taking any form of medication.
{"title":"مقایسه اثرات مصرف استروئیدهای 17-آلفا الکیلی و استرهای 17-بتا هیدروکسی بر سطوح آنزیمهای کبدی و تغییرات هماتولوژیک خون مردان رشته پرورشاندام","authors":"سیدرضا عطارزاده حسینی, امیر رشیدلمیر, محسن دهباشی","doi":"10.18869/ACADPUB.HMS.22.1.21","DOIUrl":"https://doi.org/10.18869/ACADPUB.HMS.22.1.21","url":null,"abstract":"Aims: Nowadays, using the derivatives of steroids has been increased among athletes, despite their vast gradient side effects. The aim of this study was to compare the effects of 17α-alkyl steroids and 17β-hydroxy steroids on levels of liver enzymes and hematological factors in male bodybuilders. Materials & Methods: In this causal comparing study in 2014, 24 male bodybuilders of Mashhad City, Iran, were entered to the study by census method. The samples were divided into three groups (each 8 persons); consumers of oral steroids (17α-alkyl), consumers of injected steroids (17βhydroxy) and athletes without the experience of using steroids. The blood samples from cubital vein for measurements of the liver enzymes and hematological factors were taken 48 hours after training following 12 hours of overnight fasting. Data were analyzed using ANOVA in SPSS 19 software. Findings: The level of ALT and AST enzymes in the first group were increased over the second (p=0.032) and third (p=0.001) groups significantly. The amount of red blood cells were significantly higher in second group then first and third groups and in first group than control group (p=0.01). The levels of hematocrit and hemoglobin in the first and second groups significantly were higher than third group (p=0.01). However, there were no significant differences in values of lymphocytes, Neutrophils, ALP, MCV, MCH, MCHC, WBC and PLT between the groups. Conclusion: AST and ALT enzymes merely increase by taking oral steroids (17α-alkyl); however, increase in erythrocyte, hematocrit and hemoglobin are expected by taking any form of medication.","PeriodicalId":300087,"journal":{"name":"The Horizon of Medical Sciences","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129387084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"اثر هشت هفته تمرین ترکیبی (مقاومتی و تسهیل عصبی- عضلانی گیرندههای عمقی) بر خستگی و کیفیت زندگی بیماران مبتلا به مولتیپل اسکلروزیس","authors":"آقاابراهیم عطار سیاح, سید علیرضا حسینی کاخک, محمدرضا حامدی نیا, مریم رضازاده مهرجو","doi":"10.18869/ACADPUB.HMS.22.1.43","DOIUrl":"https://doi.org/10.18869/ACADPUB.HMS.22.1.43","url":null,"abstract":"","PeriodicalId":300087,"journal":{"name":"The Horizon of Medical Sciences","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123063242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-15DOI: 10.18869/ACADPUB.HMS.21.3.181
F. Moradi
Aims: Physical exercise has anti-inflammatory effects. Interleukin-18 is an inflammatory cytokine and C-reactive protein is an acute phase protein. The purpose of this study was to determine the response of circulating levels of Interleukin-18 and high-sensitivity C-reactive protein to endurance and resistance training in inactive lean men. Materials & Methods: In a semi-expetrimental trial study in 2011 in Boukan and Saghez Cities, Iran, 28 sedentary lean men were purposefully chosen and randomly placed at 3 groups; endurance training, resistance training and control. Height, weight, body mass index, body fat percent, maximal oxygen consumption, serum levels of Interleukin-18, and high-sensitivity C-reactive protein (after12h fasting) were assessed prior to and after the training. Endurance training and resistance training were accomplished for 12 weeks. Data were analyzed using one-way ANOVA and Tukey ad hoc tests. Findings: Serum levels of Interleukin-18 (p=0.098) and high-sensitivity Creactive protein (p=0.11) were similar in three groups before the training. Also, no significant differences were observed in serum levels of Interleukin-18 (p=0.159) and high-sensitivity C-reactive protein (p=0.19) among the groups after the training. Conclusion: The circulating levels of Interleukin-18 and high-sensitivity Creactive protein do not change following 12 weeks of endurance and resistance training in inactive lean men.
{"title":"Response of Circulationg Levels of Interleukin-18 and High- Sensitivity C-Reactive Protein to Endurance and Resistance Training in Inactive Lean Men","authors":"F. Moradi","doi":"10.18869/ACADPUB.HMS.21.3.181","DOIUrl":"https://doi.org/10.18869/ACADPUB.HMS.21.3.181","url":null,"abstract":"Aims: Physical exercise has anti-inflammatory effects. Interleukin-18 is an inflammatory cytokine and C-reactive protein is an acute phase protein. The purpose of this study was to determine the response of circulating levels of Interleukin-18 and high-sensitivity C-reactive protein to endurance and resistance training in inactive lean men. Materials & Methods: In a semi-expetrimental trial study in 2011 in Boukan and Saghez Cities, Iran, 28 sedentary lean men were purposefully chosen and randomly placed at 3 groups; endurance training, resistance training and control. Height, weight, body mass index, body fat percent, maximal oxygen consumption, serum levels of Interleukin-18, and high-sensitivity C-reactive protein (after12h fasting) were assessed prior to and after the training. Endurance training and resistance training were accomplished for 12 weeks. Data were analyzed using one-way ANOVA and Tukey ad hoc tests. Findings: Serum levels of Interleukin-18 (p=0.098) and high-sensitivity Creactive protein (p=0.11) were similar in three groups before the training. Also, no significant differences were observed in serum levels of Interleukin-18 (p=0.159) and high-sensitivity C-reactive protein (p=0.19) among the groups after the training. Conclusion: The circulating levels of Interleukin-18 and high-sensitivity Creactive protein do not change following 12 weeks of endurance and resistance training in inactive lean men.","PeriodicalId":300087,"journal":{"name":"The Horizon of Medical Sciences","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129768233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-15DOI: 10.18869/ACADPUB.HMS.21.3.175
A. Borzoei, S. Sohrabi
Article Type Original Research Authors Borzoei A.* MSc, Sohrabi Sh.1 MD How to cite this article Borzoei A, Sohrabi Sh. Effect of Using Breakfast Cereals on Reducing Weight and Body Mass Index in Obese and Over-Weight Individuals. Quarterly of the Horizon of Medical Sciences. 2015;21(3):175-179. * +,-$ # $ ./ 0$ . #
{"title":"EFFECT OF USING BREAKFAST CEREALS ON REDUCING WEIGHT AND BODY MASS INDEX IN OBESE AND OVER-WEIGHT INDIVIDUALS","authors":"A. Borzoei, S. Sohrabi","doi":"10.18869/ACADPUB.HMS.21.3.175","DOIUrl":"https://doi.org/10.18869/ACADPUB.HMS.21.3.175","url":null,"abstract":"Article Type Original Research Authors Borzoei A.* MSc, Sohrabi Sh.1 MD How to cite this article Borzoei A, Sohrabi Sh. Effect of Using Breakfast Cereals on Reducing Weight and Body Mass Index in Obese and Over-Weight Individuals. Quarterly of the Horizon of Medical Sciences. 2015;21(3):175-179. * +,-$ # $ ./ 0$ . #","PeriodicalId":300087,"journal":{"name":"The Horizon of Medical Sciences","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124729590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-15DOI: 10.18869/ACADPUB.HMS.21.3.147
Jahanshir Tavakolizadeh, M. Kianmehr, M. Moghadam, M. Pahlavan
Aims: Anxiety is a common phenomenon in cardiovascular diseases and its control is very important. This study aimed to investigate the effect of guided imagery on anxiety in hospitalized patients with acute coronary syndrome in the cardiac intensive care unit. Materials & Methods: In this clinical trial in 2014, 50 patients with acute coronary syndrome in the cardiac intensive care unit of 22 Bahman Hospital in Gonabad City, Iran, were selected by convenience sampling method and were randomly divided into two control and experimental groups. At first, all the samples completed the Spielberger State Anxiety Inventory questionnaire and Visual Analog Scale of anxiety. In addition to usual care, experimental group listened to the CD of guided imagery 2 times a day, morning and night for 16 minutes and the control group received only routine care. At the end, the mentioned questionnaires were filled again and the data were analyzed in SPSS 14.5 software by independent T-test, Chi-square and Fisher exact tests. Findings: The mean of pretest and posttest scores of total anxiety and hidden anxiety in the experimental group decreased significantly compare with the control group (p 0.05). Conclusion: Guided imagery can reduce the total anxiety and hidden anxiety of heart patients with acute coronary syndrome hospitalized in cardiac intensive care unit.
{"title":"Effect of Guided Visualization on Anxiety of Patients with Acute Coronary Syndrome Admitted to the Cardiac Intensive Care Unit","authors":"Jahanshir Tavakolizadeh, M. Kianmehr, M. Moghadam, M. Pahlavan","doi":"10.18869/ACADPUB.HMS.21.3.147","DOIUrl":"https://doi.org/10.18869/ACADPUB.HMS.21.3.147","url":null,"abstract":"Aims: Anxiety is a common phenomenon in cardiovascular diseases and its control is very important. This study aimed to investigate the effect of guided imagery on anxiety in hospitalized patients with acute coronary syndrome in the cardiac intensive care unit. Materials & Methods: In this clinical trial in 2014, 50 patients with acute coronary syndrome in the cardiac intensive care unit of 22 Bahman Hospital in Gonabad City, Iran, were selected by convenience sampling method and were randomly divided into two control and experimental groups. At first, all the samples completed the Spielberger State Anxiety Inventory questionnaire and Visual Analog Scale of anxiety. In addition to usual care, experimental group listened to the CD of guided imagery 2 times a day, morning and night for 16 minutes and the control group received only routine care. At the end, the mentioned questionnaires were filled again and the data were analyzed in SPSS 14.5 software by independent T-test, Chi-square and Fisher exact tests. Findings: The mean of pretest and posttest scores of total anxiety and hidden anxiety in the experimental group decreased significantly compare with the control group (p 0.05). Conclusion: Guided imagery can reduce the total anxiety and hidden anxiety of heart patients with acute coronary syndrome hospitalized in cardiac intensive care unit.","PeriodicalId":300087,"journal":{"name":"The Horizon of Medical Sciences","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121564457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-15DOI: 10.18869/ACADPUB.HMS.21.3.155
M. Z. Bidaki, Mina Arab, M. Khazaei, Ehsan Afkar, M. Zardast
Aims: According to the worldwide development of antibiotic resistance in recent years, the tendency of using herbal medicine has grown and plants derived antibacterial substances have found many applications in controlling microorganisms. Thyme (Zataria multiflora Boiss.) is one of the medicinal herbs which its pharmaceutical and antibacterial effects have been a matter of research and debate in recent years. This research aimed to study antibacterial effects of Zataria multiflora Boiss. essence against 8 standard pathogenic bacterial species. Materials & Methods: In this experimental study, the essential oil was extracted by steam distillation using Clevenger apparatus. Using broth microdilution testing, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of thyme essential oil were determined against 8 standard pathogenic bacterial species. Each exam was repeated three times. The results were analyzed by SPSS 16 software using one-way ANOVA and Tukey statistical tests. Findings: The average of MIC for Zataria multiflora Boiss. essential oil showed a significant difference among 8 different bacterial species (p<0.001). The highest growth inhibitory effect was found against Bacillus cereus and the least one was against Pseudomonas aeruginosa. There was no significant difference among the averages of MBCs (p=0.073). Conclusion: Zataria multiflora Boiss. essential oil has significant antibacterial effect.
{"title":"Anti-Bacterial Effect of Zataria multiflora Boiss. Essential Oil on Eight Gastrointestinal Pathogenic Species","authors":"M. Z. Bidaki, Mina Arab, M. Khazaei, Ehsan Afkar, M. Zardast","doi":"10.18869/ACADPUB.HMS.21.3.155","DOIUrl":"https://doi.org/10.18869/ACADPUB.HMS.21.3.155","url":null,"abstract":"Aims: According to the worldwide development of antibiotic resistance in recent years, the tendency of using herbal medicine has grown and plants derived antibacterial substances have found many applications in controlling microorganisms. Thyme (Zataria multiflora Boiss.) is one of the medicinal herbs which its pharmaceutical and antibacterial effects have been a matter of research and debate in recent years. This research aimed to study antibacterial effects of Zataria multiflora Boiss. essence against 8 standard pathogenic bacterial species. Materials & Methods: In this experimental study, the essential oil was extracted by steam distillation using Clevenger apparatus. Using broth microdilution testing, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of thyme essential oil were determined against 8 standard pathogenic bacterial species. Each exam was repeated three times. The results were analyzed by SPSS 16 software using one-way ANOVA and Tukey statistical tests. Findings: The average of MIC for Zataria multiflora Boiss. essential oil showed a significant difference among 8 different bacterial species (p<0.001). The highest growth inhibitory effect was found against Bacillus cereus and the least one was against Pseudomonas aeruginosa. There was no significant difference among the averages of MBCs (p=0.073). Conclusion: Zataria multiflora Boiss. essential oil has significant antibacterial effect.","PeriodicalId":300087,"journal":{"name":"The Horizon of Medical Sciences","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121328586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-15DOI: 10.18869/ACADPUB.HMS.21.3.163
S. Talaei, Mojgan Mohammadifar, A. Azami, M. Salami
Aims: Melatonin modulates the function of nervous system and its secretion is dependent to circadian rhythms and visual signals. The melatonin receptors are founded in many areas of the brain. During critical period of the brain development, the structure of mammals’ brain is intensely affected by peripheral sensory signals. The aim of this study was to evaluate the effect of interaction of age and visual deprivation during critical period of brain development on melatonin receptors expression in rats’ hippocampus. Materials & Methods: This experimental study was carried on 2 groups (n=36) of male Wistar rats kept in standard 12 hour light/dark condition (Light Reared-LR) or in complete darkness (Dark Reared-DR). The rats of each groups, were introduced into the experiments at 2, 4 and 6 weeks old of age. Expression of mRNA of both melatonin receptors, MT1 and MT2, in the hippocampus was evaluated by RT-PCR and using Western Blot technique, protein expression of those receptors was investigated. Data were analyzed by one-way ANOVA with Tukey post hoc tests. Findings: The relative expression of mRNA and protein of MT1 and MT2 receptors increased about 36% in the LR animals from 2 to 6 weeks old of age (p<0.001). The visual deprivation caused a decrease of 35% and 50% in expression of MT1 and MT2 from 2 to 6 weeks old of age, respectively (p<0.001 for both comparison). Conclusion: The relative expression of both melatonin receptors in rats’ hippocampus increases across aging during critical period of brain development and visual deprivation reverses the pattern of melatonin receptors expression.
{"title":"Effect of Interaction of Age and Changing in Visual Experience During Critical Period of Brain Development on Expression of Melatonin Receptors in Rat’s Hippocampus","authors":"S. Talaei, Mojgan Mohammadifar, A. Azami, M. Salami","doi":"10.18869/ACADPUB.HMS.21.3.163","DOIUrl":"https://doi.org/10.18869/ACADPUB.HMS.21.3.163","url":null,"abstract":"Aims: Melatonin modulates the function of nervous system and its secretion is dependent to circadian rhythms and visual signals. The melatonin receptors are founded in many areas of the brain. During critical period of the brain development, the structure of mammals’ brain is intensely affected by peripheral sensory signals. The aim of this study was to evaluate the effect of interaction of age and visual deprivation during critical period of brain development on melatonin receptors expression in rats’ hippocampus. Materials & Methods: This experimental study was carried on 2 groups (n=36) of male Wistar rats kept in standard 12 hour light/dark condition (Light Reared-LR) or in complete darkness (Dark Reared-DR). The rats of each groups, were introduced into the experiments at 2, 4 and 6 weeks old of age. Expression of mRNA of both melatonin receptors, MT1 and MT2, in the hippocampus was evaluated by RT-PCR and using Western Blot technique, protein expression of those receptors was investigated. Data were analyzed by one-way ANOVA with Tukey post hoc tests. Findings: The relative expression of mRNA and protein of MT1 and MT2 receptors increased about 36% in the LR animals from 2 to 6 weeks old of age (p<0.001). The visual deprivation caused a decrease of 35% and 50% in expression of MT1 and MT2 from 2 to 6 weeks old of age, respectively (p<0.001 for both comparison). Conclusion: The relative expression of both melatonin receptors in rats’ hippocampus increases across aging during critical period of brain development and visual deprivation reverses the pattern of melatonin receptors expression.","PeriodicalId":300087,"journal":{"name":"The Horizon of Medical Sciences","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130157313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-15DOI: 10.18869/ACADPUB.HMS.21.3.169
L. Jafarzadeh, R. Habibian, M. R. Kopaei, Z. Mohammadzadeh
Aims: Kelussia odoratissima is a plant from Umbelliferae family that has nutritional and pharmacological properties. The antispasmodic effect of this plant has been mentioned in Iranian traditional medicine. The aim of study was to assess the effect of alcoholic extract of Kelussia odoratissima on uterus contractions of adult rats. Materials & Methods: In this experimental study, 16 adult female Wistar rats were studied and were randomly divided into two groups (each consisted of 8 rats); receiver of Tyrod solution (first group) and receiver of Dejalon solution (second group) groups. A 10-15mm sample of uterus smooth muscle were placed in an organ bath containing Tyrod or Dejalon solution (10ml), and contractions were recorded with Isometric method after inducing with KCl and Oxytocin. The 0.125, 0.25 and 0.5mg/ml final concentrations of the alcoholic extract of Kelussia odoratissima was added to the organ bath. Data were statistically analyzed by SPSS 17 software using repeated measures ANOVA. Findings: The alcoholic extract of Kelussia odoratissima significantly decreased the KCl-induced (p<0.001) and Oxytocin-induced (p<0.002) contractions in a concentration dependent manner. Conclusion: The alcoholic extract of Kelussia odoratissima inhibits the contractions of adult rat uterus in a concentration dependent manner.
{"title":"EFFECT OF HYDROALCOHOLIC EXTRACT OF KELUSSIA ODORATISSIMA MOZAFFARIAN ON UTERUS CONTRACTIONS OF MATURE RATS","authors":"L. Jafarzadeh, R. Habibian, M. R. Kopaei, Z. Mohammadzadeh","doi":"10.18869/ACADPUB.HMS.21.3.169","DOIUrl":"https://doi.org/10.18869/ACADPUB.HMS.21.3.169","url":null,"abstract":"Aims: Kelussia odoratissima is a plant from Umbelliferae family that has nutritional and pharmacological properties. The antispasmodic effect of this plant has been mentioned in Iranian traditional medicine. The aim of study was to assess the effect of alcoholic extract of Kelussia odoratissima on uterus contractions of adult rats. Materials & Methods: In this experimental study, 16 adult female Wistar rats were studied and were randomly divided into two groups (each consisted of 8 rats); receiver of Tyrod solution (first group) and receiver of Dejalon solution (second group) groups. A 10-15mm sample of uterus smooth muscle were placed in an organ bath containing Tyrod or Dejalon solution (10ml), and contractions were recorded with Isometric method after inducing with KCl and Oxytocin. The 0.125, 0.25 and 0.5mg/ml final concentrations of the alcoholic extract of Kelussia odoratissima was added to the organ bath. Data were statistically analyzed by SPSS 17 software using repeated measures ANOVA. Findings: The alcoholic extract of Kelussia odoratissima significantly decreased the KCl-induced (p<0.001) and Oxytocin-induced (p<0.002) contractions in a concentration dependent manner. Conclusion: The alcoholic extract of Kelussia odoratissima inhibits the contractions of adult rat uterus in a concentration dependent manner.","PeriodicalId":300087,"journal":{"name":"The Horizon of Medical Sciences","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126348837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-10DOI: 10.18869/ACADPUB.HMS.21.3.189
Akram Bagheri, F. Faeghi, M. Rabbani, K. Jabari
Aims: Magnetic resonance venography based on susceptibility weighted imaging (SWI) utilizes deoxygenated hemoglobin in veins as an intrinsic contrast medium. Magnetic susceptibility difference between deoxygenated hemoglobin, oxygenated hemoglobin and parenchyma lead to an excellent venous contrast. The purpose of this study was to evaluate the different magnetic resonance imaging sequences and susceptibility weighted imaging in the visualization of sinus venous thrombosis. Materials & Methods: This cross-sectional study was performed in Shafa Medical Imaging Center in Isfahan City, Iran, from August 2013 to September 2014 and 12 patients with sinus venous thrombosis were analyzed using MRI, SWI, and Phase contrast-magnetic resonance venography (PC-MRV). Findings: In all patients, sub-acute superior sagittal sinus, transverse and sigmoid sinuses thrombosis was most successfully detected during the susceptibility weighted imaging. In only one case, the sub-acute left transverse and sigmoid sinuses and left jugular vein of thrombosis was discernible with T1W. In 6 patients, sinus venous thrombosis was discernible with T2W in the sub-acute stage. PC-MRV showed the acute and sub-acute sinus venous thrombosis in all patients. Conclusion: Susceptibility weighted imaging has a high diagnostic value for detecting sub-acute superior sagittal sinus, transverse and sigmoid sinuses thrombosis.
{"title":"Diagnostic Value of Susceptibility Weighted Imaging in Sinus Venous Thrombosis","authors":"Akram Bagheri, F. Faeghi, M. Rabbani, K. Jabari","doi":"10.18869/ACADPUB.HMS.21.3.189","DOIUrl":"https://doi.org/10.18869/ACADPUB.HMS.21.3.189","url":null,"abstract":"Aims: Magnetic resonance venography based on susceptibility weighted imaging (SWI) utilizes deoxygenated hemoglobin in veins as an intrinsic contrast medium. Magnetic susceptibility difference between deoxygenated hemoglobin, oxygenated hemoglobin and parenchyma lead to an excellent venous contrast. The purpose of this study was to evaluate the different magnetic resonance imaging sequences and susceptibility weighted imaging in the visualization of sinus venous thrombosis. Materials & Methods: This cross-sectional study was performed in Shafa Medical Imaging Center in Isfahan City, Iran, from August 2013 to September 2014 and 12 patients with sinus venous thrombosis were analyzed using MRI, SWI, and Phase contrast-magnetic resonance venography (PC-MRV). Findings: In all patients, sub-acute superior sagittal sinus, transverse and sigmoid sinuses thrombosis was most successfully detected during the susceptibility weighted imaging. In only one case, the sub-acute left transverse and sigmoid sinuses and left jugular vein of thrombosis was discernible with T1W. In 6 patients, sinus venous thrombosis was discernible with T2W in the sub-acute stage. PC-MRV showed the acute and sub-acute sinus venous thrombosis in all patients. Conclusion: Susceptibility weighted imaging has a high diagnostic value for detecting sub-acute superior sagittal sinus, transverse and sigmoid sinuses thrombosis.","PeriodicalId":300087,"journal":{"name":"The Horizon of Medical Sciences","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125291920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-10DOI: 10.18869/ACADPUB.HMS.21.3.213
K. Mirkarimi, Mohammadreza Honarvar, Mohammad Ariaie, Rahman Bordi, Aziz Kamran
Aims: Hypertension is one of the most common chronic diseases all around the world and majority of hypertensive patients suffer from hypertension problems due to lack of treatment adherence. The current study aimed to investigate the effect of motivational interviewing on adherence to treatment in patients with hypertension and its comparison with standard cares. Materials & Methods: This randomized clinical trial was done during February to October 2014. In total, 140 of hypertensive patients were selected using multi-stage cluster sampling method from two urban health centers located in Gorgan City, Iran, with regards to the inclusion criteria and allocated randomly into two groups; motivational interviewing (70 participants) and control (70 participants). Data collecting instruments were demographic questionnaire (personal information, laboratory indices and clinical symptoms), general selfefficacy scale and treatment adherence questionnaire of patients with hypertension. Data were analyzed in SPSS 18 software using paired T and Independent T tests. Findings: Motivational interviewing increased total score and the mean score of all dimensions of the adherence questionnaire (except for weight control and stress reduction) (p<0.05). After 6 month, systolic blood pressure and diastolic blood pressure also decreased significantly in the motivational interviewing group (p<0.05). Conclusion: Motivational interviewing is likely beneficial to improve and promote medication adherence and blood pressure control in patients with hypertension.
{"title":"Effect of Motivational Interviewing on Adherence to Treatment in Patients with Hypertension","authors":"K. Mirkarimi, Mohammadreza Honarvar, Mohammad Ariaie, Rahman Bordi, Aziz Kamran","doi":"10.18869/ACADPUB.HMS.21.3.213","DOIUrl":"https://doi.org/10.18869/ACADPUB.HMS.21.3.213","url":null,"abstract":"Aims: Hypertension is one of the most common chronic diseases all around the world and majority of hypertensive patients suffer from hypertension problems due to lack of treatment adherence. The current study aimed to investigate the effect of motivational interviewing on adherence to treatment in patients with hypertension and its comparison with standard cares. Materials & Methods: This randomized clinical trial was done during February to October 2014. In total, 140 of hypertensive patients were selected using multi-stage cluster sampling method from two urban health centers located in Gorgan City, Iran, with regards to the inclusion criteria and allocated randomly into two groups; motivational interviewing (70 participants) and control (70 participants). Data collecting instruments were demographic questionnaire (personal information, laboratory indices and clinical symptoms), general selfefficacy scale and treatment adherence questionnaire of patients with hypertension. Data were analyzed in SPSS 18 software using paired T and Independent T tests. Findings: Motivational interviewing increased total score and the mean score of all dimensions of the adherence questionnaire (except for weight control and stress reduction) (p<0.05). After 6 month, systolic blood pressure and diastolic blood pressure also decreased significantly in the motivational interviewing group (p<0.05). Conclusion: Motivational interviewing is likely beneficial to improve and promote medication adherence and blood pressure control in patients with hypertension.","PeriodicalId":300087,"journal":{"name":"The Horizon of Medical Sciences","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130884367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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