Setyoadi Setyoadi, Ah. Yusuf, N. Kristianingrum, Y. Hayati, L. Noviyanti, Nurmalia Filda Syafiky
Introduction: The health status of a patient is strongly influenced by the family members because they play an important role during the health care process, and in healthy living. This implies that they must be involved in decision-making and therapeutic actions at every stage of the treatment. Therefore, this study aims to determine the relationship between family support and the health status of diabetes mellitus patients in Malang. Design and Methods: This study used a descriptive correlational design with a cross-sectional approach, which was carried out by filling questionnaires to determine the relationship between family support and the health status of diabetes mellitus patients. The sample population consists of 327 diabetes mellitus patients and 327 family caregivers of patients with the disease. Meanwhile, the respondents were selected through a cluster random sampling technique. Results: The results showed that 62.7% of the caregivers provided a good family support, while 90.8% of the patients have a good health status. This indicates that there is a positive correlation between family support and the health status of people with the disease (p-value= 0,000, α<0.05, r= 0,400). Conclusions: Further studies are advised to explore the use of nursing interventions as an effort to maintain and improve the ability of families in providing long-term care for members with diabetes mellitus.
{"title":"The correlation between family support and health status in patients with diabetes mellitus","authors":"Setyoadi Setyoadi, Ah. Yusuf, N. Kristianingrum, Y. Hayati, L. Noviyanti, Nurmalia Filda Syafiky","doi":"10.4081/hls.2023.11212","DOIUrl":"https://doi.org/10.4081/hls.2023.11212","url":null,"abstract":"Introduction: The health status of a patient is strongly influenced by the family members because they play an important role during the health care process, and in healthy living. This implies that they must be involved in decision-making and therapeutic actions at every stage of the treatment. Therefore, this study aims to determine the relationship between family support and the health status of diabetes mellitus patients in Malang. \u0000Design and Methods: This study used a descriptive correlational design with a cross-sectional approach, which was carried out by filling questionnaires to determine the relationship between family support and the health status of diabetes mellitus patients. The sample population consists of 327 diabetes mellitus patients and 327 family caregivers of patients with the disease. Meanwhile, the respondents were selected through a cluster random sampling technique. \u0000Results: The results showed that 62.7% of the caregivers provided a good family support, while 90.8% of the patients have a good health status. This indicates that there is a positive correlation between family support and the health status of people with the disease (p-value= 0,000, α<0.05, r= 0,400). \u0000Conclusions: Further studies are advised to explore the use of nursing interventions as an effort to maintain and improve the ability of families in providing long-term care for members with diabetes mellitus. \u0000 ","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49643235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. V. Suryadinata, Dwi Martha Nur Aditya, Viera Permatasari Wiana, D. Rahman
Introduction: Herbal extracts are often administered to cigarette smokers to prevent excessive free radicals. These include Brassica oleracea var. Italica, known to contain high antioxidant flavonoids and selenium micronutrients. Therefore, this study aims to determine the efficacy of Brassica oleracea var extract. italica in reducing the free radicals and inflammation present in experimental animals exposed to cigarette smoke. Design and Methods: This research was conducted based on an experimental method using a randomized controlled trial (RCT) for 21 days. The animals used were divided into six groups (negative control, positive control, and four treatments). Particularly, the positive control and treatment groups were exposed to cigarette smoke for 2 minutes, twice a day, at 50 PPM CO levels. The treatment groups were administered the extract at different doses (0.5 ml; 0.75 ml; 1 ml; 1.25 ml), before assessing the blood level of malondialdehyde and C-Reactive Protein. Result: The results showed the tendency for exposure to smoke to increase the number of free radicals and stimulate inflammation responses in the body (P<0,05). In addition, a strong correlation between variables was established (p=0.000; r=0.713). Conclusions: Broccoli extracts (Brassica oleracea L. var. Italica) administration has the potential to cause a decline in the two aspects, including free radicals and inflammation responses resulting from exposure to cigarette smoke.
{"title":"Brassica oleracea var. italica extract reducing free radicals and inflammation initiated by an exposure to cigarette smoke","authors":"R. V. Suryadinata, Dwi Martha Nur Aditya, Viera Permatasari Wiana, D. Rahman","doi":"10.4081/hls.2023.11210","DOIUrl":"https://doi.org/10.4081/hls.2023.11210","url":null,"abstract":"Introduction: Herbal extracts are often administered to cigarette smokers to prevent excessive free radicals. These include Brassica oleracea var. Italica, known to contain high antioxidant flavonoids and selenium micronutrients. Therefore, this study aims to determine the efficacy of Brassica oleracea var extract. italica in reducing the free radicals and inflammation present in experimental animals exposed to cigarette smoke. \u0000Design and Methods: This research was conducted based on an experimental method using a randomized controlled trial (RCT) for 21 days. The animals used were divided into six groups (negative control, positive control, and four treatments). Particularly, the positive control and treatment groups were exposed to cigarette smoke for 2 minutes, twice a day, at 50 PPM CO levels. The treatment groups were administered the extract at different doses (0.5 ml; 0.75 ml; 1 ml; 1.25 ml), before assessing the blood level of malondialdehyde and C-Reactive Protein. \u0000Result: The results showed the tendency for exposure to smoke to increase the number of free radicals and stimulate inflammation responses in the body (P<0,05). In addition, a strong correlation between variables was established (p=0.000; r=0.713). \u0000Conclusions: Broccoli extracts (Brassica oleracea L. var. Italica) administration has the potential to cause a decline in the two aspects, including free radicals and inflammation responses resulting from exposure to cigarette smoke. \u0000 ","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44042078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: The caregivers of people with schizophrenia have problems that include high family, burden and low quality of life at home. Therefore, this study aims to determine the effectiveness of nursing psychoeducation on family, burdens and quality of life in caregivers of schizophrenia patients in the community. Design and Methods: This study used a pre-test and post-test group control design and repeated measurement with a total of 100 respondents. The treatment group was given weekly nursing psychoeducation for seven sessions. Also, the general linear model (GLM) was used to analyze the result. Results: This study showed that before the intervention of nursing psychoeducation, the average family burden was 49,02 and 46.28 in the treatment and control groups, respectively. This decreased to 38.24 and 37.56 in the first and fourth weeks of posttreatment. Meanwhile, the control group was 44.86 in the first week and 45.62 in the fourth. The psychoeducation had an effect on decreasing the family burden with a p value < 0.001. Moreover, this study showed that before the intervention of nursing psychoeducation, the average caregiver quality of life was 75,72 and 74.24 in the treatment. After treatment, it increased to 91.22 in the first week after intervention and 92.54 in the fourth week of post-intervention. Therefore, the intervention effectively improved the caregiver quality of life with p < 0.001 Conclusions: Nursing psychoeducation can effectively reduce family burdens and improve the quality of life for caregivers.
{"title":"The effectiveness of nursing psychoeducation toward family burden and quality life on caregiver of people with schizophrenia in the community","authors":"S. Suharsono, Noor Faidah, M. Hanafi","doi":"10.4081/hls.2023.11215","DOIUrl":"https://doi.org/10.4081/hls.2023.11215","url":null,"abstract":"Introduction: The caregivers of people with schizophrenia have problems that include high family, burden and low quality of life at home. Therefore, this study aims to determine the effectiveness of nursing psychoeducation on family, burdens and quality of life in caregivers of schizophrenia patients in the community. \u0000Design and Methods: This study used a pre-test and post-test group control design and repeated measurement with a total of 100 respondents. The treatment group was given weekly nursing psychoeducation for seven sessions. Also, the general linear model (GLM) was used to analyze the result. \u0000Results: This study showed that before the intervention of nursing psychoeducation, the average family burden was 49,02 and 46.28 in the treatment and control groups, respectively. This decreased to 38.24 and 37.56 in the first and fourth weeks of posttreatment. Meanwhile, the control group was 44.86 in the first week and 45.62 in the fourth. The psychoeducation had an effect on decreasing the family burden with a p value < 0.001. Moreover, this study showed that before the intervention of nursing psychoeducation, the average caregiver quality of life was 75,72 and 74.24 in the treatment. After treatment, it increased to 91.22 in the first week after intervention and 92.54 in the fourth week of post-intervention. Therefore, the intervention effectively improved the caregiver quality of life with p < 0.001 \u0000Conclusions: Nursing psychoeducation can effectively reduce family burdens and improve the quality of life for caregivers. \u0000 ","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46612097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tony Suharsono, S. Sunarmi, N. Ida, Bella Nove Khirria, Nazla Asrin, Ikhda Ulya
Introduction: In-Hospital Cardiac Arrest (IHCA) is a frequent occurrence that necessitates prompt and appropriate assistance to improve survival rates. Nurses in public care rooms and outpatients are expected to be first responders to IHCA until an activated hospital code blue team arrives. Therefore, this study aims to analyze the implementation of code blue response by nurses in outpatient and hospital inpatient rooms in Malang. Design and Methods: This is a quantitative study that uses observational methods with a cross-sectional approach comprising of 109 inpatient and outpatient care room nurses from 9 hospitals in Malang. The implementation of code blue was measured by a simulated case of adult cardiac arrest in a hospital inpatient room. Results: The nurses involved were 67.0% female, where the majority have a D3 education qualification (57.7%), with more than ten years working experience (45%). Furthermore, 83.5% of nurses work in regular care rooms and 16.5% come from outpatient rooms. The results showed that the implementation of code blue by nurses in regular care and inpatient rooms was 66.7% and 65.9%, respectively in the insufficient categories. In addition, the Mann-Whitney U test obtained a p-value of 0.929. Conclusions: In conclusion, there was no significant difference in the implementation of code blue that occurred in the inpatient and outpatient rooms. Further studies were recommended to observe code blue events directly and take samples with balanced proportions.
{"title":"The implementation of code blue by nurses as first responders in outpatient and inpatient rooms at Malang Indonesia Hospital","authors":"Tony Suharsono, S. Sunarmi, N. Ida, Bella Nove Khirria, Nazla Asrin, Ikhda Ulya","doi":"10.4081/hls.2023.11217","DOIUrl":"https://doi.org/10.4081/hls.2023.11217","url":null,"abstract":"Introduction: In-Hospital Cardiac Arrest (IHCA) is a frequent occurrence that necessitates prompt and appropriate assistance to improve survival rates. Nurses in public care rooms and outpatients are expected to be first responders to IHCA until an activated hospital code blue team arrives. Therefore, this study aims to analyze the implementation of code blue response by nurses in outpatient and hospital inpatient rooms in Malang. \u0000Design and Methods: This is a quantitative study that uses observational methods with a cross-sectional approach comprising of 109 inpatient and outpatient care room nurses from 9 hospitals in Malang. The implementation of code blue was measured by a simulated case of adult cardiac arrest in a hospital inpatient room. \u0000Results: The nurses involved were 67.0% female, where the majority have a D3 education qualification (57.7%), with more than ten years working experience (45%). Furthermore, 83.5% of nurses work in regular care rooms and 16.5% come from outpatient rooms. The results showed that the implementation of code blue by nurses in regular care and inpatient rooms was 66.7% and 65.9%, respectively in the insufficient categories. In addition, the Mann-Whitney U test obtained a p-value of 0.929. \u0000Conclusions: In conclusion, there was no significant difference in the implementation of code blue that occurred in the inpatient and outpatient rooms. Further studies were recommended to observe code blue events directly and take samples with balanced proportions. \u0000 ","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44970430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ni Nyoman Elfiyunai, N. Nursalam, Tintin Sukartini, Ferry Efendi
Introduction: The COVID-19 pandemic had made patients scared of coming to clinics or hospitals, and this could affect the treatment of TB. Therefore, one type of service that can be used by nurses to improve compliance to TB treatment is Telenursing. This article aims to ascertain whether telenursing could be a solution in improving the compliance of TB patients to treatments in the COVID-19 pandemic. Design and Method: This research was conducted using the Randomised Controlled Trial design as well as PRISMA. Furthermore, useful research articles were sourced from the database using the keywords, “Message Reminder and Tuberculosis OR Medication Adherence”. The databases used are Scopus, Science Direct, PubMed, and SAGE, all in English text and from 2015 to 2021, with inclusion criteria. 277 articles were obtained, and then filtered to select 3 articles by reading the main focus of the write-up, with regard to the topic of study. Result: Telenursing can be a solution to reduce the spread of COVID-19, and a substitute for remotely motivating individuals, as social support. Furthermore, it could be used as a reminder to patients to be obedient in carrying out treatments, and as a means of educating and improving good relationships with providers. Conclusions: Telenursing is a fairly effective solution in helping TB patients improve treatment compliance, reduce drug dropout rates and missed doses, as well as, raise awareness about the importance of health in the COVID-19 pandemic.
{"title":"A systematic review on telenursing as a solution in improving the treatment compliance of tuberculosis patients in the COVID-19 pandemic","authors":"Ni Nyoman Elfiyunai, N. Nursalam, Tintin Sukartini, Ferry Efendi","doi":"10.4081/hls.2023.11194","DOIUrl":"https://doi.org/10.4081/hls.2023.11194","url":null,"abstract":"Introduction: The COVID-19 pandemic had made patients scared of coming to clinics or hospitals, and this could affect the treatment of TB. Therefore, one type of service that can be used by nurses to improve compliance to TB treatment is Telenursing. This article aims to ascertain whether telenursing could be a solution in improving the compliance of TB patients to treatments in the COVID-19 pandemic. \u0000Design and Method: This research was conducted using the Randomised Controlled Trial design as well as PRISMA. Furthermore, useful research articles were sourced from the database using the keywords, “Message Reminder and Tuberculosis OR Medication Adherence”. The databases used are Scopus, Science Direct, PubMed, and SAGE, all in English text and from 2015 to 2021, with inclusion criteria. 277 articles were obtained, and then filtered to select 3 articles by reading the main focus of the write-up, with regard to the topic of study. \u0000Result: Telenursing can be a solution to reduce the spread of COVID-19, and a substitute for remotely motivating individuals, as social support. Furthermore, it could be used as a reminder to patients to be obedient in carrying out treatments, and as a means of educating and improving good relationships with providers. \u0000Conclusions: Telenursing is a fairly effective solution in helping TB patients improve treatment compliance, reduce drug dropout rates and missed doses, as well as, raise awareness about the importance of health in the COVID-19 pandemic. \u0000 ","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46912992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mifetika Lukitasari, W. Windarti, Endah Panca Lydia Fatma, Tony Suharsono, D. Nugroho
Introduction: The number of confirmed COVID-19 cases has increased in Indonesia. Preventive measures are believed to break the chain of transmission of COVID-19. Therefore, increasing knowledge through health education is essential to improve preventive behavior in the community. The study aims to determine the efficacy of implementing health education using Raspberry Pi based automatic voice massages in increasing high risk populations’ knowledge and prevention behavior. Design and Methods: This study was a quasi-interventional method with a pre-posttest research design and a non-equivalent control group, consisting of 30 respondents in each group. Control group received health education through leaflet sharing, while intervention group received health education through Raspberry-pi based automatic voice massages. Results: This study showed that there were no significant different in knowledge between control and intervention group after obtaining health education. Meanwhile, the intervention group showed higher score in knowledge regarding COVID-19. Moreover, the prevention behavior was significantly improved in both groups after acquiring health education through leaflets and automatic voice messages. Conclusions: Health education using Raspberry Pi based automatic voice messages improved both knowledge and preventive behavior regarding COVID 19 in high risk population.
{"title":"The efficacy of Raspberry Pi-based automatic voice message education on knowledge level and prevention behavior of high-risk population","authors":"Mifetika Lukitasari, W. Windarti, Endah Panca Lydia Fatma, Tony Suharsono, D. Nugroho","doi":"10.4081/hls.2023.11178","DOIUrl":"https://doi.org/10.4081/hls.2023.11178","url":null,"abstract":"Introduction: The number of confirmed COVID-19 cases has increased in Indonesia. Preventive measures are believed to break the chain of transmission of COVID-19. Therefore, increasing knowledge through health education is essential to improve preventive behavior in the community. The study aims to determine the efficacy of implementing health education using Raspberry Pi based automatic voice massages in increasing high risk populations’ knowledge and prevention behavior. \u0000Design and Methods: This study was a quasi-interventional method with a pre-posttest research design and a non-equivalent control group, consisting of 30 respondents in each group. Control group received health education through leaflet sharing, while intervention group received health education through Raspberry-pi based automatic voice massages. \u0000Results: This study showed that there were no significant different in knowledge between control and intervention group after obtaining health education. Meanwhile, the intervention group showed higher score in knowledge regarding COVID-19. Moreover, the prevention behavior was significantly improved in both groups after acquiring health education through leaflets and automatic voice messages. \u0000Conclusions: Health education using Raspberry Pi based automatic voice messages improved both knowledge and preventive behavior regarding COVID 19 in high risk population.","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47481514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Kristianingrum, Delfira Arizda, Setyoadi Setyoadi, Y. Hayati, M. Parchman
Introduction: Chronic conditions due to diabetes cause changes in patients’ health status and their family has importantroles in the health care. Therefore, this study aimed to analyze the relationship between family health task implementation and the health status of diabetics. Design and methods: An observational analytic design with a cross-sectional approach was used, while the respondents consisted of 327 family caregivers and 327 diabetes mellitus patients. This study used both family health task implementation and Short Form Health Survey (SF-12) questionnaires. Results: The result of the Pearson Product Moment test showed a correlation coefficient of 0.593 and a 0.000 p-value (α 0.05). Conclusions: It was concluded that there was a fairly strong relationship between family health task implementation and the health status of diabetes mellitus patients. Nursing intervention is needed to improve the implementation of family health tasks.
{"title":"Family health task implementation and the health status of diabetes mellitus patients: A correlational study","authors":"N. Kristianingrum, Delfira Arizda, Setyoadi Setyoadi, Y. Hayati, M. Parchman","doi":"10.4081/hls.2023.11195","DOIUrl":"https://doi.org/10.4081/hls.2023.11195","url":null,"abstract":"Introduction: Chronic conditions due to diabetes cause changes in patients’ health status and their family has importantroles in the health care. Therefore, this study aimed to analyze the relationship between family health task implementation and the health status of diabetics. \u0000Design and methods: An observational analytic design with a cross-sectional approach was used, while the respondents consisted of 327 family caregivers and 327 diabetes mellitus patients. This study used both family health task implementation and Short Form Health Survey (SF-12) questionnaires. \u0000Results: The result of the Pearson Product Moment test showed a correlation coefficient of 0.593 and a 0.000 p-value (α 0.05). \u0000Conclusions: It was concluded that there was a fairly strong relationship between family health task implementation and the health status of diabetes mellitus patients. Nursing intervention is needed to improve the implementation of family health tasks.","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46879929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alma Maghfirotun Innayah, Elvira Nur Sa’idah Hariani, H. Khotimah, I. Kusumastuty, E. Yunita, D. Handayani
Introduction: The increasing consumption of high-fat and high-fructose foods contributes to the increasing prevalence of global obesity. Low-grade chronic inflammation in obesity is a significant risk factor for insulin resistance and type 2 diabetes. Therefore, this study aimed to determine the effect of β-(1,3)-D-glucan from oyster mushroom (Pleurotus ostreatus) extract on rats fed with a high-fat and high-fructose diet. Design and Methods: This experimental study was conducted on 35 male Sprague-Dawley rats aged eight weeks. The rats were divided into groups given a normal (N) diet, a high-fat and high-fructose diet (HFFD), D1 (HFFD+125 mg/kg BW β-glucan), D2 (HFFD+250 mg/kg BW β glucan), and D3 (HFFD+375 mg/kg BW β-glucan) with an intervention of 14 weeks. IL-6 and IL-1β levels were measured by the ELISA method, while HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) was calculated by the fasting insulin (ng/mL) x fasting blood glucose (mg/dL)/405 formula. Pancreatic beta-cell counts were measured by hematoxylin and eosin (H&E) staining. Results: The results showed no differences in IL-6 and IL-1β between the treatment groups. However, there were significant differences in HOMA-IR and pancreatic beta-cell counts between groups. There were negative correlations between the dose of β-glucan and IL-6, IL-1β, and HOMA-IR levels. Also, there was a positive correlation between the dose of β-glucan and the number of pancreatic beta cells. Conclusions: Administration of β-(1,3)-D-glucan from oyster mushroom (Pleurotus ostreatus) extract prevented hyperglycemia and insulin resistance, also reduced inflammation in rats fed with HFFD regardless of weight gain.
导读:高脂肪和高果糖食品消费的增加导致全球肥胖患病率的上升。肥胖患者的轻度慢性炎症是胰岛素抵抗和2型糖尿病的重要危险因素。因此，本研究旨在研究从平菇(Pleurotus ostreatus)中提取的β-(1,3)- d -葡聚糖对高脂高果糖饮食大鼠的影响。设计与方法:以35只8周龄雄性Sprague-Dawley大鼠为实验对象。将大鼠分为正常组(N)、高脂高果糖组(HFFD)、D1组(HFFD+125 mg/kg BW β-葡聚糖)、D2组(HFFD+250 mg/kg BW β-葡聚糖)、D3组(HFFD+375 mg/kg BW β-葡聚糖)，干预14周。采用ELISA法测定IL-6、IL-1β水平，采用空腹胰岛素(ng/mL) ×空腹血糖(mg/dL)/405计算HOMA-IR(胰岛素抵抗稳态模型评估)。苏木精和伊红(H&E)染色测定胰腺β细胞计数。结果:两组间IL-6、IL-1β水平无明显差异。然而，两组间HOMA-IR和胰腺β细胞计数有显著差异。β-葡聚糖剂量与IL-6、IL-1β、HOMA-IR水平呈负相关。此外，β-葡聚糖的剂量与胰腺β细胞的数量呈正相关。结论:在不影响体重增加的情况下，给予平菇提取物β-(1,3)- d -葡聚糖可预防高血糖和胰岛素抵抗，并减轻炎症反应。
{"title":"β-(1,3)-D-glucan from Pleurotus ostreatus correlates with lower plasma IL-6, IL-1β, HOMA-IR, and higher pancreatic beta cell count in High-Fat and High-Fructose Diet (HFFD) rats","authors":"Alma Maghfirotun Innayah, Elvira Nur Sa’idah Hariani, H. Khotimah, I. Kusumastuty, E. Yunita, D. Handayani","doi":"10.4081/hls.2023.11165","DOIUrl":"https://doi.org/10.4081/hls.2023.11165","url":null,"abstract":"Introduction: The increasing consumption of high-fat and high-fructose foods contributes to the increasing prevalence of global obesity. Low-grade chronic inflammation in obesity is a significant risk factor for insulin resistance and type 2 diabetes. Therefore, this study aimed to determine the effect of β-(1,3)-D-glucan from oyster mushroom (Pleurotus ostreatus) extract on rats fed with a high-fat and high-fructose diet.\u0000Design and Methods: This experimental study was conducted on 35 male Sprague-Dawley rats aged eight weeks. The rats were divided into groups given a normal (N) diet, a high-fat and high-fructose diet (HFFD), D1 (HFFD+125 mg/kg BW β-glucan), D2 (HFFD+250 mg/kg BW β glucan), and D3 (HFFD+375 mg/kg BW β-glucan) with an intervention of 14 weeks. IL-6 and IL-1β levels were measured by the ELISA method, while HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) was calculated by the fasting insulin (ng/mL) x fasting blood glucose (mg/dL)/405 formula. Pancreatic beta-cell counts were measured by hematoxylin and eosin (H&E) staining.\u0000Results: The results showed no differences in IL-6 and IL-1β between the treatment groups. However, there were significant differences in HOMA-IR and pancreatic beta-cell counts between groups. There were negative correlations between the dose of β-glucan and IL-6, IL-1β, and HOMA-IR levels. Also, there was a positive correlation between the dose of β-glucan and the number of pancreatic beta cells.\u0000Conclusions: Administration of β-(1,3)-D-glucan from oyster mushroom (Pleurotus ostreatus) extract prevented hyperglycemia and insulin resistance, also reduced inflammation in rats fed with HFFD regardless of weight gain.","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43515075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahsan Ahsan, Imeldha Monitasari, E. Ningrum, Ike Nesdia Rahmawati, L. Noviyanti, K. Putra
Introduction: Patient safety is a healthcare system, which minimizes the occurrence and impact of side effects. It also helps to facilitate full recovery in patients, and efforts to improve their safety require teamwork, such as situation monitoring by nurses. Therefore, this study aims to determine the effects of TeamSTEPPS implementation by nurses on situation monitoring in hospitals. Design and Methods: A quasi-experimental pre-post test design was used with a total of 56 nurses, which were selected using the purposive sampling technique. They were then shared equally into 2 groups, namely control and intervention groups. Results: The unpaired t-test result shows that the value of |t count| was lower than the t table (0.210 < 2.005), while the p-value was greater than α (0.835 > 0.050). This result indicates that implementing TeamSTEPPS by nurses have an insignificant effect on situation monitoring in the hospital. Conclusions: In conclusion, hospitals are advised to implement TeamSTEPPS regularly to improve teamwork, specifically in situation monitoring by nurses.
{"title":"The effects of TeamSTEPPS implementation by nurses on situation monitoring in hospital","authors":"Ahsan Ahsan, Imeldha Monitasari, E. Ningrum, Ike Nesdia Rahmawati, L. Noviyanti, K. Putra","doi":"10.4081/hls.2023.11163","DOIUrl":"https://doi.org/10.4081/hls.2023.11163","url":null,"abstract":"Introduction: Patient safety is a healthcare system, which minimizes the occurrence and impact of side effects. It also helps to facilitate full recovery in patients, and efforts to improve their safety require teamwork, such as situation monitoring by nurses. Therefore, this study aims to determine the effects of TeamSTEPPS implementation by nurses on situation monitoring in hospitals.\u0000Design and Methods: A quasi-experimental pre-post test design was used with a total of 56 nurses, which were selected using the purposive sampling technique. They were then shared equally into 2 groups, namely control and intervention groups.\u0000Results: The unpaired t-test result shows that the value of |t count| was lower than the t table (0.210 < 2.005), while the p-value was greater than α (0.835 > 0.050). This result indicates that implementing TeamSTEPPS by nurses have an insignificant effect on situation monitoring in the hospital.\u0000Conclusions: In conclusion, hospitals are advised to implement TeamSTEPPS regularly to improve teamwork, specifically in situation monitoring by nurses.","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43483409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: One impact on People With Mental Disorders (PSMD) is decreased productivity. As the closest people, families are expected to support PSMD to be productive in the community. Therefore, this study aimed to identify the correlation between family support and the work productivity of people with mental disorders. Design and Methods: This observational analytical study with a Cross-Sectional approach was conducted in the working area of the Bantur Community Health Center. Purposive sampling was used to obtain 107 samples. Data on family support were collected using a questionnaire and tested for validity, while the Endicott Work Productivity Scale (EWPS) questionnaire was used to measure PSMD work productivity. Results: The results showed a significant correlation between family support and PSMD work productivity, p = 0.028. The correlation was negative, meaning lower PSMD work productivity implied higher family support. Furthermore,emotional support was the most form of support provided by family members to PSMD. Work productivity is generally low, with PSMD work attitudes in the high category only in sub-variables. Conclusions: Family support is needed for people with mental disorders to be productive. Future studies should examine other factors that affect PSMD work productivity. Additionally, health services should innovate to create work programs that stimulate PSMD's potential and ability.
{"title":"Correlation between family support with work productivity of people with severe mental disorders (PSMD) in Bantur Community Health Center, Malang, Indonesia","authors":"Renny Nova, H. Windarwati, Erik Meidianto","doi":"10.4081/hls.2023.11207","DOIUrl":"https://doi.org/10.4081/hls.2023.11207","url":null,"abstract":"Introduction: One impact on People With Mental Disorders (PSMD) is decreased productivity. As the closest people, families are expected to support PSMD to be productive in the community. Therefore, this study aimed to identify the correlation between family support and the work productivity of people with mental disorders. \u0000Design and Methods: This observational analytical study with a Cross-Sectional approach was conducted in the working area of the Bantur Community Health Center. Purposive sampling was used to obtain 107 samples. Data on family support were collected using a questionnaire and tested for validity, while the Endicott Work Productivity Scale (EWPS) questionnaire was used to measure PSMD work productivity. \u0000Results: The results showed a significant correlation between family support and PSMD work productivity, p = 0.028. The correlation was negative, meaning lower PSMD work productivity implied higher family support. Furthermore,emotional support was the most form of support provided by family members to PSMD. Work productivity is generally low, with PSMD work attitudes in the high category only in sub-variables. \u0000Conclusions: Family support is needed for people with mental disorders to be productive. Future studies should examine other factors that affect PSMD work productivity. Additionally, health services should innovate to create work programs that stimulate PSMD's potential and ability.","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42163731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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