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Clinical Audit of Obstructive Sleep Apnea: A Case Study in Sleep Disorders 阻塞性睡眠呼吸暂停的临床审计:一个睡眠障碍的案例研究
Pub Date : 2022-12-19 DOI: 10.5812/jhrt-131339
Mehdi Mirzaei Alavijeh, Habibolah Khazaie, A. Alipourian, Sepideh Khazaie, Negar Karimi, Nafiseh Mirzaei Alavijeh, Soroush Maazinezhad, F. Jalilian
Background: Clinical audit (CA) is a standard method for improving the quality of health service. Objectives: This study aimed to determine the CA status of obstructive sleep apnea (OSA) clinical services at the sleep disorders research center of Kermanshah University of Medical Sciences (KUMS), Iran. Methods: The current research was conducted on 91 patients with OSA records in 2019 - 2020. The CA steps were performed, and the data extracted from the checklist were described using SPSS software version 16. Results: The age average of the patients was 50.10 (standard deviation = 13.16), ranging from 16 to 76 years. The services were provided to all patients (100%) based on indicators such as training in a healthy lifestyle related to OSA (weight control, not drinking alcohol, and sleep health behaviors) and appropriate prescribing of medications and devices, including continuous positive airway pressure (CPAP) and bilevel positive airway pressure (BiPAP). Follow-up on prescribing CPAP and BiPAP devices, informing patients about the frequency of possible surgeries, and follow-up treatment were weak indicators and did not follow the standards. Conclusions: Based on the results, the treatment follow-up indicators of OSA patients are not in compliance with the standards, and attention must be paid to these indicators in providing clinical services to OSA patients in western Iran.
背景:临床审计是提高医疗服务质量的一种标准方法。目的:本研究旨在确定伊朗Kermanshah医科大学(KUMS)睡眠障碍研究中心阻塞性睡眠呼吸暂停(OSA)临床服务的CA状态。方法:选取2019 - 2020年有OSA记录的91例患者为研究对象。执行CA步骤,并使用SPSS软件版本16描述从检查表中提取的数据。结果:患者平均年龄为50.10岁(标准差为13.16),年龄范围16 ~ 76岁。为所有患者(100%)提供的服务基于与OSA(体重控制、不饮酒和睡眠健康行为)相关的健康生活方式培训以及适当的药物和设备处方,包括持续气道正压通气(CPAP)和双水平气道正压通气(BiPAP)。CPAP和BiPAP设备处方的随访、告知患者可能手术的频率、随访治疗等指标较弱,不符合标准。结论:综上所述,伊朗西部地区OSA患者的治疗随访指标不符合标准,在为OSA患者提供临床服务时必须注意这些指标。
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引用次数: 0
The Relationship Between Organizational Pathology and Employees’ Organizational Commitment in Qazvin University of Medical Sciences 卡兹温医科大学组织病理与员工组织承诺的关系
Pub Date : 2022-12-13 DOI: 10.5812/jhrt-120576
S. Rafiei, Zahra Nejatifar, A. Alizadeh, Mohammad Amerzadeh, Solmaz Babajamadi, Marzye Farmani, Ashkan Ghader Abadi, Somayeh Amini
Background: In today's constantly changing world, educational organizations regularly renew their fundamental goals as a factor of development and transformation in society. Objectives: Therefore, this study aimed to evaluate the relationship between organizational pathology and employees' organizational commitment. Methods: This descriptive-analytical and cross-sectional study was conducted in 2020 among the headquarter employees at Qazvin University of Medical Sciences, Iran. The data were collected using Meyer and Allen standard organizational pathology and organizational commitment questionnaires. In addition, R software version 4.0.3, Spearman or Pearson correlation statistical methods, and multiple linear regression coefficient analysis were utilized to analyze the data based on the research objectives. Results: A total of 101 participants were male and 125 were female. There was a statistically significant correlation between organizational pathology and organizational commitment. The organizational commitment increased by increasing pathology (r = 0.1640, P-value = 0.019). The transparency of goals and the organization mission significantly affected the normative scale. The normative scale decreased by 0.35 by increasing one unit of the scale in the transparency of goals and organization mission (B = -0.038, P-value = 0.038). There was a direct and significant relationship between organizational pathology and organizational commitment. Conclusions: According to the results, university administrators and policymakers are recommended to take measures to coordinate employees' interests and individual goals with the organization’s interests and goals. Managers can provide employees with a clear and concise vision by expressing short- and long-term goals and planning, allowing employees to know the value of their actions to achieve the goals.
背景:在当今不断变化的世界中,教育组织作为社会发展和变革的一个因素,经常更新其基本目标。目的:本研究旨在探讨组织病理与员工组织承诺之间的关系。方法:本研究于2020年在伊朗Qazvin医科大学总部员工中进行了描述性分析和横断面研究。采用Meyer和Allen标准组织病理学问卷和组织承诺问卷收集数据。根据研究目的,采用R软件4.0.3版本、Spearman或Pearson相关统计方法、多元线性回归系数分析法对数据进行分析。结果:男性101人,女性125人。组织病理与组织承诺有显著的相关。病理程度越高,组织承诺越高(r = 0.1640, p值= 0.019)。目标透明度和组织使命对规范量表有显著影响。在目标和组织使命的透明度上,每增加一个单位,规范量表降低0.35 (B = -0.038, p值= 0.038)。组织病理与组织承诺之间存在显著的直接关系。结论:根据研究结果,建议大学管理者和政策制定者采取措施,协调员工的利益和个人目标与组织的利益和目标。管理者可以通过表达短期和长期的目标和计划,为员工提供一个清晰而简洁的愿景,让员工知道他们为实现目标而采取的行动的价值。
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引用次数: 0
The Effect of Sexual Education of Adolescent Girls Through Problem-Solving on Their Mental Health 问题解决性教育对少女心理健康的影响
Pub Date : 2022-11-29 DOI: 10.5812/jhrt-120445
Minoo Jananeh, Seyed Sajjad Hoseini, K. Kakabaraei
Background: Adolescent puberty issues can be solved by applying a practical problem-solving approach. Objectives: This study aimed to evaluate the sexual education of adolescent girls through a problem-solving training approach and its effect on their mental health. Methods: The present study used the random sampling method to select 30 students (15 experimental and 15 control) based on a pre-test and post-test design with a control group. The data collection tool was Goldberg’s abbreviated mental health questionnaire. The experimental group was educated in a problem-solving approach for treating sexual problems in 10 sessions, and the control group received no intervention. Results: The problem-based sexual education training significantly affected mental health in adolescent girls. In addition, the LSD post hoc test differed significantly between pre-test and follow-up tests. Conclusions: Based on the results, the problem-based sexual education could increase young girls’ and their parents’ awareness of the developmental period and the characteristics of puberty. This method helped deal with emotional states and sexual issues related to puberty. Therefore, practitioners are recommended to provide sexual education for adolescents and their families at a low cost and with easy understanding.
背景:青春期的问题可以通过实际的解决问题的方法来解决。目的:探讨问题解决训练法对青春期少女的性教育及其对心理健康的影响。方法:本研究采用随机抽样的方法,采用前测和后测设计,抽取30名学生,其中试验组15名,对照组15名。数据收集工具是Goldberg的简短心理健康问卷。实验组接受了为期10次的性问题解决方法教育,对照组则不接受任何干预。结果:基于问题的性教育培训对少女心理健康有显著影响。此外,LSD事后测试在测试前和随访测试之间存在显著差异。结论:基于问题的性教育可以提高女童及其家长对发育时期和青春期特征的认识。这种方法有助于处理与青春期有关的情绪状态和性问题。因此,我们建议从业员为青少年及其家庭提供成本低、易懂的性教育。
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引用次数: 0
The Effectiveness of Group Dialectical Behavior Therapy and Structured Matrix Treatment on Quit Addiction Self-efficacy, Distress Tolerance, and Mindfulness in Individuals with Stimulant Drug Abuse 团体辩证行为疗法和结构矩阵疗法对兴奋剂滥用者戒瘾自我效能感、痛苦耐受性和正念的影响
Pub Date : 2022-11-28 DOI: 10.5812/jhrt-127427
Sakineh Basereh, S. Safarzadeh, F. Hooman
Background: Drug abuse causes irreversible damage to human health at both micro and macro levels among the aggravating problems of human society. Objectives: This research aimed to evaluate the role of group dialectical behavior therapy (DBT) and structured matrix treatment (SMT) on quit addiction self-efficacy, distress tolerance, and mindfulness in individuals with stimulant drug abuse. Methods: This quasi-experimental study was based on a pretest-posttest design with test and control groups. The population included drug abusers referring to the centers of addiction rehabilitation affiliated with the Social Welfare Department, Ahvaz, Iran, in 2021. A total of 75 individuals were selected using convenience sampling and allocated to one control group and two experimental groups. Participants in all three groups completed the Distress Tolerance Scale (DTS), the Mindful Attention Awareness Scale (MAAS), and the Quit Addiction Self-Efficacy Questionnaire. The first experimental groups underwent eight sessions (90-minute sessions per week) of group DBT. The SMT was performed on the second experimental group for fourteen 90-minute sessions, and the control group did not receive any training. Then, the data were analyzed statistically using the multivariate analysis of covariance. Results: DBT and SMT groups increased quit addiction self-efficacy, distress tolerance, and mindfulness in the experimental group compared to the control group (P < 0.001). There was a significant difference between DBT and SMT groups regarding distress tolerance in the individuals with stimulant drug abuse (P = 0.020). Conclusions: Based on the results, DBT and SMT were effective in quitting addiction self-efficacy, distress tolerance, and mindfulness among drug abusers, improved psychological states, and reduced drug abuse in individuals.
背景:药物滥用在微观和宏观层面上对人类健康造成不可逆转的损害,是人类社会日益严重的问题之一。目的:探讨团体辩证行为疗法(DBT)和结构矩阵疗法(SMT)对兴奋剂滥用者戒瘾自我效能感、痛苦耐受性和正念的影响。方法:准实验研究采用前测后测设计,分为试验组和对照组。其中包括2021年在伊朗阿瓦士社会福利部下属的戒毒所的吸毒者。采用方便抽样法,选取75人分为对照组和试验组。三组参与者均完成了痛苦容忍量表(DTS)、正念注意意识量表(MAAS)和戒瘾自我效能问卷。第一组实验组接受8次DBT治疗(每周90分钟)。第二个实验组进行了14次90分钟的SMT训练,对照组没有接受任何训练。然后,使用协方差的多变量分析对数据进行统计分析。结果:与对照组相比,DBT组和SMT组戒烟成瘾自我效能感、痛苦耐受性和正念均有显著提高(P < 0.001)。DBT组和SMT组在兴奋剂滥用个体的痛苦耐受性方面存在显著差异(P = 0.020)。结论:DBT和SMT能有效改善吸毒者的戒毒自我效能感、痛苦耐受性和正念,改善个体的心理状态,减少药物滥用。
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引用次数: 2
A SWOT Analysis of the Experiences of a District Hospital in Ghana During the COVID-19 Pandemic 新冠肺炎疫情期间加纳某地区医院经验的SWOT分析
Pub Date : 2022-11-21 DOI: 10.5812/jhrt-118356
K. Mensah, Akosua Ofosua Asante
Background: District-level hospitals in developing countries have unique resource challenges which have been strained by the COVID-19 pandemic and yet, they have been expected to maintain deliverables. The resource restrictions brought about by the COVID-19 pandemic continues to impact the post-pandemic recovery of clinical care in Ghana. Individual institutions now have the uphill task of turning around their fortunes and restoring service quality. Objectives: An assessment, from a strategic management perspective, of how events unfolded at the Agogo Presbyterian Hospital (APH), a secondary centre in Ghana, during the peak of the COVID-19 pandemic could offer useful pointers for the future of healthcare in low-resource settings. Methods: This study reviewed the handling of the COVID-19 pandemic in the Agogo Presbyterian Hospital (APH). Decisions from meetings of the clinical team and the specially constituted ‘COVID-19 task force’ were examined. This information was subjected to a deductive Strength-Weakness-Opportunities-Threats (SWOT) analysis to identify and summarize the major themes emerging. Results: As a strength for APH during the peak of the pandemic, the surgical division defied pandemic projections by recording an increased volume of surgical procedures in 2020. As a key weakness, APH was unable to utilize virtual meeting platforms during the pandemic lockdown period. Regarding opportunities, APH became the beneficiary of relief donations from many first-time partners who were poised to continue this relationship beyond the COVID-19 era. As a threat, the drop in the hospital attendance and the consequent dip in revenue uncovered the dangers of APH’s over-reliance on a single revenue stream. Conclusions: A SWOT analysis of the events in APH during the peak of the COVID-19 pandemic brings into focus the relevant directions in which a district-level hospital needs to channel its limited resources for sustainable benefits that would survive future health crises.
背景:发展中国家的区级医院面临着独特的资源挑战,受到COVID-19大流行的压力,但人们期望它们保持可交付成果。COVID-19大流行带来的资源限制继续影响加纳大流行后临床护理的恢复。单个机构现在面临着扭转命运和恢复服务质量的艰巨任务。目标:从战略管理的角度评估2019冠状病毒病大流行高峰期间加纳二级医疗中心阿戈戈长老会医院(APH)发生的事件,可以为资源不足地区的医疗保健未来提供有用的指导。方法:对阿戈戈长老会医院(APH)处理新冠肺炎疫情的情况进行综述。审查了临床小组会议和专门组成的“COVID-19工作队”的决定。这些信息是经过演绎的优势-劣势-机会-威胁(SWOT)分析,以确定和总结出现的主要主题。结果:作为APH在大流行高峰期的一个优势,外科科室在2020年记录了增加的外科手术量,打破了大流行的预测。作为一个关键弱点,APH在疫情封锁期间无法利用虚拟会议平台。在机会方面,APH成为许多首次合作伙伴的救济捐款的受益者,这些合作伙伴准备在COVID-19时代之后继续保持这种关系。作为一种威胁,医院出勤率的下降和随之而来的收入下降,暴露了APH过度依赖单一收入来源的危险。结论:通过对2019冠状病毒病大流行高峰期APH事件的SWOT分析,重点关注了区级医院需要将有限资源用于可持续效益的相关方向,以应对未来的卫生危机。
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引用次数: 0
Detectable Antibodies in Newborn Cord Blood Following Maternal COVID-19 Infection Before Pregnancy: A Case Report 孕妇妊娠前感染COVID-19后新生儿脐带血可检测抗体1例报告
Pub Date : 2022-11-21 DOI: 10.5812/jhrt-128799
A. Coşkun, Selda Yüzer Alsaç
: In this report, we present a case of an infant with detectable antibodies in the umbilical cord blood who was born to a healthcare professional mother diagnosed with coronavirus disease 2019 (COVID-19) before pregnancy and recovered, and also discuss the antibody level in light of relevant literature. Data consisted of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) polymerase chain reaction (PCR) test and negative pre-pregnancy repeat real-time polymerase chain reaction (RT-PCR) test of a 29-year-old medical doctor mother, follow-up antibody test results in pregnancy, and antibodies detected in the cord blood of the newborn after birth. The study data were collected through face-to-face interviews with the mother. In conclusion, this case shows that SARS-CoV-2 immunoglobulin G (IgG) antibodies can be detected in the baby’s cord blood immediately after birth from a mother who was diagnosed with COVID-19 before becoming pregnant and subsequently recovered with pharmacological treatment.
本报告报告了一名医务人员在孕前诊断为2019冠状病毒病(COVID-19)的母亲所生的婴儿脐带血中可检测到抗体的病例,并结合相关文献讨论了抗体水平。资料包括对一名29岁的医生母亲进行严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)聚合酶链反应(PCR)检测和孕前重复实时聚合酶链反应(RT-PCR)阴性检测,妊娠期随访抗体检测结果,新生儿出生后脐带血抗体检测结果。研究数据是通过与母亲面对面访谈收集的。总之,该病例表明,在怀孕前被诊断患有COVID-19并随后通过药物治疗康复的母亲出生后,可以在婴儿的脐带血中立即检测到SARS-CoV-2免疫球蛋白G (IgG)抗体。
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引用次数: 0
A Comparison of Adverse Reactions of the First Dose of Gam-COVID-vac (Sputnik V), Oxford/AstraZeneca COVID-19 Vaccine, Bharat Biotech (Covaxin), and (Sinopharm) BBIBP-CorV Vaccines Gam-COVID-vac (Sputnik V)、牛津/阿斯利康 COVID-19 疫苗、巴拉特生物技术公司 (Covaxin) 和(国药集团)BBIBP-CorV 疫苗首剂不良反应的比较
Pub Date : 2022-11-10 DOI: 10.5812/jhrt-122479
H. Samimagham, M. Hassani Azad, M. Arabi, Sobhan Montazer Ghaem, Kimiya Jafari, D. Hooshyar, Mitra Kazemi Jahromi
{"title":"A Comparison of Adverse Reactions of the First Dose of Gam-COVID-vac (Sputnik V), Oxford/AstraZeneca COVID-19 Vaccine, Bharat Biotech (Covaxin), and (Sinopharm) BBIBP-CorV Vaccines","authors":"H. Samimagham, M. Hassani Azad, M. Arabi, Sobhan Montazer Ghaem, Kimiya Jafari, D. Hooshyar, Mitra Kazemi Jahromi","doi":"10.5812/jhrt-122479","DOIUrl":"https://doi.org/10.5812/jhrt-122479","url":null,"abstract":"<jats:p />","PeriodicalId":304466,"journal":{"name":"Journal of Health Reports and Technology","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115475470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the Level of Lighting Satisfaction and Determining Degrees of Visual Fatigue, Mental Task Load, Sleepiness, and Sleep Quality in Students 学生对照明满意度的评估及视觉疲劳、精神任务负荷、嗜睡和睡眠质量程度的测定
Pub Date : 2022-07-02 DOI: 10.5812/jhrt-118006
E. Hoseinzadeh, Atefeh Ramezani, Farshid Mohammadi, M. Safari, A. Sokan-Adeaga, H. Hossini
: Lighting affects humans in many ways, including intelligence, body temperature, and sleep patterns. This study aimed to evaluate lighting satisfaction, mental task load, visual fatigue, and sleep quality in students. The present cross-sectional study was conducted on 100 students of Saveh Faculty of Nursing and Midwifery, Iran, in 2020. The data of their levels of lighting satisfaction, mental task level, visual fatigue, and sleep quality were collected using standard questionnaires and analyzed using SPSS Software version 21. The quantitative variables were reported in mean and standard deviation and qualitative variables in frequency and percentage. A chi-square test was used to compare qualitative variables. In addition, the independent t-test was applied to compare the sleepiness score according to the relevant variables and the Pearson correlation test was utilized to investigate the relationship between sleepiness and sleep quality scores. The significance level was less than 0.05 for all statistical tests. The results indicated that the students’ satisfaction scores with current lighting were indifference. Visual fatigue was low, and sleepiness was mild. The students' subjective task load and sleep quality were moderate and low. There was a significant inverse relationship between visual fatigue and lighting satisfaction (P < 0.001). In addition, visual fatigue and task load had a significant direct relationship (P < 0.001). The average number of hours of sleep per night was 6.72 hours for students, which was less than the normal recommended amount. The average sleep quality was 11.06, which was low in the population. According to the results, the students’ mental task load and sleep quality were medium and low. It seems necessary to pause and rest between training, increase the variety of educational activities, appropriate training, and lighting intervention.
当前位置光线在很多方面影响着人类,包括智力、体温和睡眠模式。本研究旨在评估学生的照明满意度、心理任务负荷、视觉疲劳和睡眠质量。本横断面研究是在2020年对伊朗Saveh护理和助产学院的100名学生进行的。采用标准问卷收集受试者的照明满意度、心理任务水平、视觉疲劳、睡眠质量等数据,采用SPSS软件21版进行分析。定量变量以均值和标准差报告,定性变量以频率和百分比报告。采用卡方检验比较定性变量。此外,根据相关变量,采用独立t检验比较困倦评分,采用Pearson相关检验考察困倦与睡眠质量评分之间的关系。所有统计检验的显著性水平均小于0.05。结果表明,学生对当前照明的满意度得分不显著。视疲劳低,嗜睡轻度。学生主观任务负荷和睡眠质量处于中、低水平。视觉疲劳与照明满意度呈显著负相关(P < 0.001)。此外,视觉疲劳与任务负荷有显著的直接关系(P < 0.001)。学生每晚平均睡眠时间为6.72小时,低于正常推荐量。平均睡眠质量为11.06,在人群中较低。结果显示,学生的心理任务负荷和睡眠质量分别为中、低。似乎有必要在训练之间暂停和休息,增加教育活动的多样性,适当的训练和照明干预。
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引用次数: 1
Evaluation of Candida auris Colonization using Clinical Skin Swabs: A Single-Center Study in Isfahan, Iran 使用临床皮肤拭子评估耳念珠菌定植:伊朗伊斯法罕的一项单中心研究
Pub Date : 2022-07-02 DOI: 10.5812/jhrt-121844
F. Safari, M. Madani, H. Mirhendi, M. Kheirollahi
: The multidrug-resistant fungal pathogen Candida auris has been associated with healthcare. We need to address COVID-19 pandemic as well as the ongoing global fungal epidemic caused by C. auris, a multi-drug-resistant fungus spreading rapidly throughout the world. This study was conducted on patients admitted to an ICU in Isfahan, Iran, from November 2020 to February 2021 to determine the spectrum of C. auris colonization in immunocompromised patients hospitalized in an intensive care unit (ICU). Therefore, clinical swabs were collected from 32 immunocompromised patients for C. auris detection upon ICU admission after 7 to 14 days. A rich culture medium was used to evaluate C. auris growth at a higher temperature (40°C) and salinity (10% wt/vol) in Sabouraud dextrose agar, which can be used in combination with a C. auris-specific polymerase chain reaction method. C. auris was not isolated in the clinical samples of patients. The most common colonizer was Candida albicans, followed by C. glabrata, C. parapsilosis, and C. tropicalis. Candida glabrata was the only species with noticeable growth in the Salt SDA, with D-Mannitol as a carbon source. Currently, C. auris is not a common cause of systemic or superficial fungal infections in Iran. The screening of patients admitted to the ICU for C. auris could aid in the identification of colonized patients and could simplify the application of infection control measures.
多重耐药真菌病原体耳念珠菌与医疗保健有关。我们需要应对COVID-19大流行,以及由金黄色葡萄球菌(C. auris)引起的持续全球真菌流行,这是一种在世界各地迅速蔓延的多重耐药真菌。本研究于2020年11月至2021年2月在伊朗伊斯法罕ICU住院的患者中进行,以确定重症监护病房(ICU)免疫功能受损患者的耳球菌定植谱。因此,32例免疫功能低下患者于7 ~ 14天后入ICU时采集临床拭子检测金黄色葡萄球菌。在Sabouraud葡萄糖琼脂较高温度(40°C)和盐度(10% wt/vol)条件下,采用富培养基对金黄色葡萄球菌进行生长评价,该培养基可与金黄色葡萄球菌特异性聚合酶链反应法结合使用。患者临床标本中未分离到金黄色葡萄球菌。最常见的定殖菌为白色念珠菌,其次为光秃念珠菌、傍裂念珠菌和热带念珠菌。以甘露醇为碳源的光念珠菌是盐湖SDA中唯一生长显著的菌种。目前,在伊朗,耳念珠菌不是引起全身或浅表真菌感染的常见原因。对入住ICU的患者进行金黄色葡萄球菌筛查有助于确定定植患者,简化感染控制措施的应用。
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引用次数: 1
Non-alcoholic Steatohepatitis Diagnosis and Treatment Medical and Surgery, Based on Guideline Updates: A Mini Review 基于指南更新的非酒精性脂肪性肝炎内科和外科诊断和治疗:一个小型综述
Pub Date : 2022-06-28 DOI: 10.5812/jhrt-119454
M. Arabi, Raheleh Alimoradzadeh, A. Makian, Seyed Javad Shariat Nabavi, Farshad Divsalar, Mitra Kazemi Jahromi
: Nonalcoholic fatty liver disease (NAFLD) refers to fat accumulation in hepatic cells due to alcohol consumption, hepatitis, and drugs. The prevalence of this disease has been reported at 20 - 50% in western and 12 - 13% in Latin countries. Patients who suffer from obesity, diabetes, and insulin resistance may be affected more than others. This disease is symptomless, and its paraclinical diagnosis is achievable by increasing the hepatic enzymes. Ultrasonography and fibroscan are some of the common diagnostic methods for this disease. The first treatment for this disease is weight loss and physical activities. Vitamin E can improve histopathological changes in terms of medications. While pioglitazone is an effective blood sugar-lowering drug, metformin has no role in treating diabetes or prediabetes.
非酒精性脂肪性肝病(NAFLD)是指由于饮酒、肝炎和药物引起的肝细胞脂肪堆积。据报道,该病的患病率在西方国家为20 - 50%,在拉丁国家为12 - 13%。患有肥胖、糖尿病和胰岛素抵抗的患者可能比其他人受到的影响更大。这种疾病无症状,通过增加肝酶可实现临床旁诊断。超声检查和纤维扫描是本病的常用诊断方法。治疗这种疾病的第一种方法是减肥和体育活动。就药物而言,维生素E可以改善组织病理变化。虽然吡格列酮是一种有效的降糖药物,但二甲双胍在治疗糖尿病或前驱糖尿病方面没有作用。
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引用次数: 0
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