{"title":"Meslek Hastalıkları Polikliniğine Başvuranlarda Yaşam Kalitesi Düzeyi ve İlişkili Faktörlerin Değerlendirilmesi","authors":"Seher Kurtul, Funda KAYA AK, Meral Türk","doi":"10.17944/mkutfd.978078","DOIUrl":"https://doi.org/10.17944/mkutfd.978078","url":null,"abstract":"","PeriodicalId":30746,"journal":{"name":"Mustafa Kemal Universitesi Tip Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49564569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Our aim was to investigate the immunohistochemical expression of β-catenin and Sox-2 in adenomatous polyps and adenocarcinoma of colon and also to evaluate the effects of these markers in adenoma-carcinoma sequence and their association with clinicopathological parameters. Methods: Fifty-six tubular adenomas with low grade dysplasia (TALGD), 53 tubular adenomas with high grade dysplasia (TAHGD), 44 tubulovillous adenomas (TVA), 29 villous adenomas (VA) and 60 adenocarcinomas were included in the study. The nuclear staining of Sox2 was evaluated as well as both nuclear and cytoplasmic stainings of β-catenin. A semiquantitative scoring was performed. The results were compared between the groups and the relationship of the results with clinicopathological parameters was evaluated. Results: Nuclear and cytoplasmic β-catenin expressions of the adenocarcinomas were higher than polyps. The expressions in the VA and TVA polyp groups were higher than the expressions in TAHGD and TALGD, respectively. Membranous β-catenin expression in the adenocarcinoma was higher than the polyps except VA. The evaluation between polyp groups with respect to membranous β-catenin staining revealed a statistically significantly difference in favor of VA compared with TVA, TAHGD and TALGD; in favor of TAHGD compared with TVA, in favor of TVA compared with TALGD while it was found statistically significantly higher in TAHGD than TALGD. Conclusion: The results regarding β-catenin expression of the polyp groups were consistent with the literature. There was a positive correlation between β-catenin expression (nuclear and cytoplasmic) and malignancy. High Sox2 expressions were found correlated with malignancy potential. Large sampling size investigations to be supported by further molecular studies are needed to clarify the effect of Sox2 expression in the sequence of adenoma-carcinoma comprehensively.
{"title":"Kolon adenokarsinomlarında ve adenomatöz poliplerinde Beta-Catenin ve Sox2 ekspresyonu ve klinikopatolojik parametreler ile ilişkileri","authors":"Neslihan Güney, İclal Gürses, Ebru SERİNSÖZ LİNKE, Didar Gürsoy, Enver Üçbilek, T. Çolak","doi":"10.17944/mkutfd.962373","DOIUrl":"https://doi.org/10.17944/mkutfd.962373","url":null,"abstract":"Objective: Our aim was to investigate the immunohistochemical expression of β-catenin and Sox-2 in adenomatous polyps and adenocarcinoma of colon and also to evaluate the effects of these markers in adenoma-carcinoma sequence and their association with clinicopathological parameters. \u0000Methods: Fifty-six tubular adenomas with low grade dysplasia (TALGD), 53 tubular adenomas with high grade dysplasia (TAHGD), 44 tubulovillous adenomas (TVA), 29 villous adenomas (VA) and 60 adenocarcinomas were included in the study. The nuclear staining of Sox2 was evaluated as well as both nuclear and cytoplasmic stainings of β-catenin. A semiquantitative scoring was performed. The results were compared between the groups and the relationship of the results with clinicopathological parameters was evaluated. \u0000Results: Nuclear and cytoplasmic β-catenin expressions of the adenocarcinomas were higher than polyps. The expressions in the VA and TVA polyp groups were higher than the expressions in TAHGD and TALGD, respectively. Membranous β-catenin expression in the adenocarcinoma was higher than the polyps except VA. The evaluation between polyp groups with respect to membranous β-catenin staining revealed a statistically significantly difference in favor of VA compared with TVA, TAHGD and TALGD; in favor of TAHGD compared with TVA, in favor of TVA compared with TALGD while it was found statistically significantly higher in TAHGD than TALGD. \u0000Conclusion: The results regarding β-catenin expression of the polyp groups were consistent with the literature. There was a positive correlation between β-catenin expression (nuclear and cytoplasmic) and malignancy. High Sox2 expressions were found correlated with malignancy potential. Large sampling size investigations to be supported by further molecular studies are needed to clarify the effect of Sox2 expression in the sequence of adenoma-carcinoma comprehensively.","PeriodicalId":30746,"journal":{"name":"Mustafa Kemal Universitesi Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67638734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sol Meme Kanseri Tanılı Olgularda Farklı Radyoterapi Teknikleri için Brakial Pleksus, Karotis Arter ve Tiroid Dozlarının Değerlendirilmesi","authors":"Gökçen İnan, Osman Vefa Gül, Hamit Başaran","doi":"10.17944/mkutfd.1002684","DOIUrl":"https://doi.org/10.17944/mkutfd.1002684","url":null,"abstract":"","PeriodicalId":30746,"journal":{"name":"Mustafa Kemal Universitesi Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67624206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Kaya, Seyma Trabzon, Selma Altındiş, Ruveyda Alacahan
Objective: This study was conducted to determine the changes in nutrition and hygiene habits of university students and their fear levels of COVID-19 during the COVID-19 pandemic period. Methods: The study was conducted through an online questionnaire with the students who were studying at Sakarya University Health Services Vocational School and Health Sciences University Hamidiye Vocational School of Health between May-June 2020 and accepted to participate in the study. The data were analyzed in SPSS 21 program, p
{"title":"The relationship between changing nutrition and hygiene habits and coronavirus fear levels during the COVID-19 pandemic process in university students receiving health education","authors":"G. Kaya, Seyma Trabzon, Selma Altındiş, Ruveyda Alacahan","doi":"10.17944/mkutfd.1055630","DOIUrl":"https://doi.org/10.17944/mkutfd.1055630","url":null,"abstract":"Objective: This study was conducted to determine the changes in nutrition and hygiene habits of university students and their fear levels of COVID-19 during the COVID-19 pandemic period. \u0000Methods: The study was conducted through an online questionnaire with the students who were studying at Sakarya University Health Services Vocational School and Health Sciences University Hamidiye Vocational School of Health between May-June 2020 and accepted to participate in the study. The data were analyzed in SPSS 21 program, p","PeriodicalId":30746,"journal":{"name":"Mustafa Kemal Universitesi Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67624435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Yaşlı Bakımı Programında Öğrenim Gören Öğrencilerde Akran Desteği Yaşlı Ayrımcılığına İlişkin Tutumu Etkiler mi?","authors":"S. Demir, Emre Erkal, Bedriye Cansu Demi̇rkiran","doi":"10.17944/mkutfd.1020621","DOIUrl":"https://doi.org/10.17944/mkutfd.1020621","url":null,"abstract":"","PeriodicalId":30746,"journal":{"name":"Mustafa Kemal Universitesi Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67624262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ThinPrep Sıvı Bazlı Sitoloji Yöntemiyle Hazırlanan Servikal Smear Materyallerinin Değerlendirilmesi, Sito-Histopatolojik Korelasyon","authors":"Hale Demir","doi":"10.17944/mkutfd.985667","DOIUrl":"https://doi.org/10.17944/mkutfd.985667","url":null,"abstract":"","PeriodicalId":30746,"journal":{"name":"Mustafa Kemal Universitesi Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67639649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Assessment of asthma and chronic obstructive pulmonary disease awareness in university students Objective: The study was aimed to identify the awareness of the chronic obstructive pulmonary disease (COPD) and asthma among university students and to compare awareness of COPD and asthma at the faculty of health science and education. Method: The universe of this cross-sectional observational study was students at Faculty of Health Science and Education in Hatay Mustafa Kemal University. Students divided into two groups (Group I: 317 Faculty of Health Science students, and Group II: 308 Faculty of Education students). TC Ministry of Health Chronic Airway Diseases Prevention Control Program Asthma-COPD Awareness Questionnaire Form was applied to volunteer face to face or via the internet. Results: Correct answers about COPD awareness were approximately above 70% except for questions: “Is COPD a treatable disease?” and “What test is required for the diagnosis of COPD?”. Correct answers about asthma awareness were approximately above 60% except for questions “Are asthma medications addictive?” and “Is asthma a disease that can be cured completely?”. The questions about awareness of COPD and asthma were answered more correctly in Group I more than in Group II except for questions: “In which age group is COPD most common” and “Are asthma medications addictive?” (p<0.05). Conclusion: COPD and asthma awareness was greater in students from the health sciences faculty than those from the education faculty. However, the university students showed an inadequate knowledge of the diagnosis and management of COPD and the medication and management of asthma. It is thought that providing education and awareness about chronic respiratory diseases to all university students will facilitate disease management
{"title":"Assessment of Asthma and Chronic Obstructive Pulmonary Disease Awareness in University Students","authors":"Nihan Katayıfçı, İrem Hüzmeli̇, Nursel Dikmen, Bircan Yucekaya","doi":"10.17944/mkutfd.1019255","DOIUrl":"https://doi.org/10.17944/mkutfd.1019255","url":null,"abstract":"Assessment of asthma and chronic obstructive pulmonary disease awareness in university students Objective: The study was aimed to identify the awareness of the chronic obstructive pulmonary disease (COPD) and asthma among university students and to compare awareness of COPD and asthma at the faculty of health science and education. Method: The universe of this cross-sectional observational study was students at Faculty of Health Science and Education in Hatay Mustafa Kemal University. Students divided into two groups (Group I: 317 Faculty of Health Science students, and Group II: 308 Faculty of Education students). TC Ministry of Health Chronic Airway Diseases Prevention Control Program Asthma-COPD Awareness Questionnaire Form was applied to volunteer face to face or via the internet. Results: Correct answers about COPD awareness were approximately above 70% except for questions: “Is COPD a treatable disease?” and “What test is required for the diagnosis of COPD?”. Correct answers about asthma awareness were approximately above 60% except for questions “Are asthma medications addictive?” and “Is asthma a disease that can be cured completely?”. The questions about awareness of COPD and asthma were answered more correctly in Group I more than in Group II except for questions: “In which age group is COPD most common” and “Are asthma medications addictive?” (p<0.05). Conclusion: COPD and asthma awareness was greater in students from the health sciences faculty than those from the education faculty. However, the university students showed an inadequate knowledge of the diagnosis and management of COPD and the medication and management of asthma. It is thought that providing education and awareness about chronic respiratory diseases to all university students will facilitate disease management","PeriodicalId":30746,"journal":{"name":"Mustafa Kemal Universitesi Tip Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48001154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Pneumothorax in Neonatal Intensive Care Unit","authors":"N. Melekoglu, M. S. Sinanoglu, Erhan Berk","doi":"10.17944/mkutfd.991806","DOIUrl":"https://doi.org/10.17944/mkutfd.991806","url":null,"abstract":"","PeriodicalId":30746,"journal":{"name":"Mustafa Kemal Universitesi Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67639880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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