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Quality of life of patients with lower jaw benign tumor post resection and mandibular reconstruction 下颌骨良性肿瘤切除术及下颌骨重建术后患者的生活质量
Pub Date : 2020-07-15 DOI: 10.22146/MAJKEDGIIND.35990
Pingky Krisna Arindra, Bramasto Purbo Sejati, Rahardjo Rahardjo
The quality of life of patients becomes an essential part of the success of an intervention since it is used as an outcome measure. Mandible resection will cause discontinuities that can degrade the quality of life of patients. Extensive resectionand reconstruction will affect the quality of life of patients after resection and reconstruction surgery as compared with that before the surgery. On this basis, cross-sectional study was conducted among 27 patients suffering from benignmandibular tumors undergoing surgical procedure of marginal resection, segmental resection, or hemimandibulectomy at Dr. Sardjito genral hospital in 2010-2015. Quality of life of patients after mandibular resection and reconstruction was measured with modified oral health impact profile (OHIP-14). An assessment of the quality of life before and after surgery was based on gender and type of reconstruction and it was analyzed using t-test and one-way ANOVA. It was revealed that the quality of life of patients with benign tumors increased significantly (p=0,000), and that gender differences did not significantly affect the improved quality of life (p=0.433). The mean score of patient’s quality of life was highest on the type of marginal resection (mean value =14.50), and the lowest was on segmental resection (mean value=7.50), but the type of resection did not significantly influence the improved quality of life (p=0.152). Resection and reconstruction procedures under taken by Oral and Maxillofacial Surgeon at Dr. Sardjito general hospital can improve the quality of life of patients with benign tumors of the lower jaw.
患者的生活质量成为干预成功的重要组成部分,因为它被用作结果衡量标准。下颌骨切除会造成不连续性,从而降低患者的生活质量。与术前相比,大面积切除重建会影响患者术后的生活质量。在此基础上,对2010-2015年在Dr. Sardjito总医院接受边缘切除、节段切除或半下颌部切除术的27例下颌良性肿瘤患者进行横断面研究。采用改进的口腔健康影响量表(OHIP-14)测量下颌切除术重建后患者的生活质量。根据性别和重建类型对手术前后的生活质量进行评估,并使用t检验和单因素方差分析进行分析。结果显示,良性肿瘤患者的生活质量明显提高(p= 0000),性别差异对改善的生活质量无显著影响(p=0.433)。边缘切除的患者生活质量平均评分最高(平均值=14.50),节段切除的患者生活质量平均评分最低(平均值=7.50),但切除类型对患者生活质量的改善无显著影响(p=0.152)。Sardjito博士综合医院的口腔颌面外科医生进行的切除和重建手术可以提高下颌良性肿瘤患者的生活质量。
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引用次数: 0
Dealing with the high-risk potential of COVID-19 cross-infection in dental practice 应对牙科执业中新型冠状病毒交叉感染的高危因素
Pub Date : 2020-07-15 DOI: 10.22146/MAJKEDGIIND.56588
H. Yulianto, N. Purwanti, T. Utami, Anne Handrini Dewi, Dyah Listyarifah, Intan Ruspita, Asikin Nur, H. Susilowati
The World Health Organization reported that the SARS-CoV-2 virus has infected more than 5 million people around the world. Dental care providers and health care professionals need to be aware of the high-risk potential of crossinfection since the routes of virus transmission commonly happen through droplets and aerosols. This review aimed at collecting essential knowledge about the COVID-19 needed by dental practitioners. The review focused on the oral involvement in COVID-19, the role of oral transmission as the high-risk potential of cross-infection and recommended strategies to minimize the risk of cross-infection in dental practice. We searched all the published clinical features from PubMed, Google Scholar, Scopus and hand searched library online databases, from January 2015 until May 2020. Keywords used were “COVID-19”, “Dentistry”, “Dental protection”, “Cross-contamination”, “Aerosol and non aerosol”, and ”Povidone-iodine” with their combinations. We identified 52 articles to review after the initial selection with inclusion and exclusion criteria. Results showed use of topical applications of povidine-iodine and viricidal mouthwash could significantly reduce the high-risk of cross-infection from dentistry patients who are asymptomatic with COVID-19 infection. Further safeguards include suspending all non-emergency procedures temporarily and closely screening patients for symptoms which may be suspected to be COVID-19 infection.
世界卫生组织报告称,SARS-CoV-2病毒已在全球感染了500多万人。牙科保健提供者和卫生保健专业人员需要意识到交叉感染的高风险可能性,因为病毒的传播途径通常是通过飞沫和气溶胶。本综述旨在收集牙科医生所需的COVID-19基本知识。综述的重点是口腔与COVID-19的关系、口腔传播作为交叉感染的高风险潜在因素的作用以及建议的策略,以尽量减少牙科实践中交叉感染的风险。从2015年1月至2020年5月,我们检索了PubMed、Google Scholar、Scopus和手工检索的图书馆在线数据库中所有已发表的临床特征。关键词为“COVID-19”、“牙科”、“牙齿防护”、“交叉污染”、“气溶胶和非气溶胶”、“聚维酮-碘”及其组合。在初步选择后,我们确定了52篇文章进行纳入和排除标准的审查。结果显示,局部应用聚维碘和杀病毒漱口水可显著降低无症状牙科患者的交叉感染风险。进一步的保障措施包括暂时暂停所有非紧急程序,并密切筛查可能被怀疑为COVID-19感染的患者症状。
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引用次数: 2
Quality of life patients after treatment of mandibular fractures with ORIF in oral surgery departement of Dr. Sardjito general hospital Sardjito博士总医院口腔外科应用ORIF治疗下颌骨骨折后患者的生活质量
Pub Date : 2020-07-15 DOI: 10.22146/MAJKEDGIIND.41145
Edmond Apriza, Rahardjo Rahardjo, C. Hasan
Management of mandibular fracture using open reduction Internal fixation (ORIF) method is one of the ideal treatments for single and multiple mandibular fractures. The aim of this study was to determine the quality of life of patients after the treatment of mandibular fractures with ORIF using miniplate in single and multiple mandibular fractures. This research used case-control by recalling 43 research subjects in the oral surgery department Dr Sardjito general hospital between 2013 and 2017, that consisted of patients suffering from 23 single fractures and 20 multiple mandibular fractures. Each fracture would be examined clinically and subjectively. Clinical examination parameters were conducted using the mandibular mobility index (MMI) consisting of mouth opening assessment, left and right lateral mandibular excursion, and mandibular protrusive movement. Subjective parameters were performed based on general oral health asseesment index (GOHAI) questionnaire to assess physiological aspects, psychosocial aspects, and pain. The results of the chi-square test statistic study showed that the quality of life of a patient with a single mandibular fracture was better than that of multiple mandibular fractures based on MMI and GOHAI examinations. It was concluded that patients with a single mandibular fracture had a younger age, longer time adaptation and have a better quality of life.
切开复位内固定(ORIF)是治疗单发或多发下颌骨骨折的理想方法之一。本研究的目的是确定使用微型钢板ORIF治疗单发和多发下颌骨骨折后患者的生活质量。本研究采用病例对照的方法,回顾2013 - 2017年Sardjito博士综合医院口腔外科43例研究对象,其中23例为单侧骨折,20例为多发骨折。对每一处骨折进行临床和主观检查。临床检查参数采用下颌活动指数(MMI),包括开口评估、下颌左右外侧偏移和下颌前突运动。采用口腔健康综合评估指数(GOHAI)进行主观参数评估,包括生理方面、心理社会方面和疼痛。卡方检验统计研究结果显示,MMI和GOHAI检查显示,单发下颌骨骨折患者的生活质量优于多发下颌骨骨折患者。结论:单纯性下颌骨骨折患者年龄较轻,适应时间较长,生活质量较好。
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引用次数: 1
The effect of bitter gourd (Momordica charantia) ethanolic extract on inflammatory infiltrates and NF-κB activation in periodontitis 苦瓜醇提物对牙周炎炎症浸润及NF-κB活化的影响
Pub Date : 2019-12-02 DOI: 10.22146/majkedgiind.31579
Aryudhi Armis, T. Haniastuti, H. Susilowati
Periodontitis is a periodontal disease involving the gingiva, periodontal ligament, cementum, and alveolar bone due to an inflammatory process. Virulence factors of periodontopathogens and inflammatory responses in periodontitis can stimulate nuclear factor-kappa B (NF-κB) activity. Charantoside c and Momordicosides g in bitter gourd prevent NF-κB activation stimulated by TNF-α in HepG2 cells. This study aims to determine the effect of bitter gourd fruit (Momordica charantia) ethanolic extract as an anti-inflammatory substance on the level of inflammatory infiltrates and the number of cells that experience NF-κB activation in the periodontitis model. Eighty male Wistar rats were divided into 5 groups. The mandibular incisors were ligated for 14 days to induce periodontitis. Each group was given Momordica charantia extract of 500 mg/kg BW, 250 mg/kg BW, and 100 mg/kg BW; ibuprofen 100 mg/kg BW; and aquades orally using oral gavage on the day 14. Rat necropsy was carried out on day 1, 3, 5, and 7 after giving the substances. Taking out the lower jaw was done to make tissue preparations followed by staining them with hematoxylin eosin (HE). Immunohistochemicalanalysis was performed to observe cells that were positive for NF-κB activation. The results showed a decrease in the density of inflammatory infiltrates in all groups, except for those given aquades. The number of inflammatory cells ofneutrophils, macrophages, and lymphocytes that experienced NF-κB activation showed the most effective decrease in the group of Momordica charantia 500 mg/kg BW, on the 7th day. The conclusion of this study is that ethanolic extractof Momordica charantia has an anti-inflammatory effect and prevents the activation of NF-kB in rat gingival induced by periodontitis. The highest effect was found at a dose of 500 mg/kg BW on day 7 after giving of extracts.
牙周炎是一种由于炎症过程而累及牙龈、牙周韧带、牙骨质和牙槽骨的牙周疾病。牙周炎的毒力因子和炎症反应可刺激核因子κB (NF-κB)活性。苦瓜中紫菜苷c和苦瓜苷g对TNF-α刺激的HepG2细胞NF-κB活化有抑制作用。本研究旨在探讨苦瓜醇提物作为抗炎物质对牙周炎模型中炎症浸润水平及NF-κB活化细胞数量的影响。80只雄性Wistar大鼠分为5组。结扎下颌门牙14 d诱导牙周炎。各组分别给予苦瓜提取物500 mg/kg BW、250 mg/kg BW和100 mg/kg BW;布洛芬100 mg/kg BW;第14天采用灌胃法灌胃。给药后第1、3、5、7天进行大鼠尸检。取下颌骨进行组织准备,苏木精伊红(HE)染色。免疫组化分析观察NF-κB活化阳性细胞。结果显示,除给药组外,其余各组炎症浸润密度均降低。500mg /kg BW的苦瓜组在第7天中性粒细胞、巨噬细胞和淋巴细胞中NF-κB活化的炎症细胞数量减少效果最好。结论苦瓜醇提物具有抗炎作用,可抑制牙周炎所致大鼠牙龈NF-kB的激活。在给药后第7天,剂量为500 mg/kg BW时效果最高。
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引用次数: 1
Deflection test on different orthodontic wire materials sized 0.016 x 0.022 inches 对尺寸为0.016 x 0.022英寸的不同正畸金属丝材料进行挠度试验
Pub Date : 2019-09-19 DOI: 10.22146/majkedgiind.31236
Harris Gadih Pratomo, Endah Mardiati, E. S. Soemantri, I. A. Evangelina
The development of technology in orthodontic field produces some orthodontic wires that have different deflection abilities. Loading force is the force needed to place an orthodontic wire in bracket slot (activation). Unloading force is the force produced by an orthodontic wire to move tooth (deactivation). Deflection test with three-point bending technique is a technique that is often used to determine the magnitude of the activation and deactivation force of orthodontic wire. Stainless steel (SS), nickel titanium (NiTi), copper nickel titanium (CuNiTi), and beta titanium (TMA), are the types of frequently used wires. This study aimed to compare loading and unloading force on the deflection test of SS, NiTi, CuNiTi, and TMA orthodontic wires sized 0.016 x 0.022 inch on the load-deflection graph. This is a laboratoryexperimental research on a total of 16 pieces of SS, NiTi, CuNiTi, and TMA orthodontic wires sized 0.016 x 0.022 inches. The group was divided based on the type of material. The deflection test was performed using a universal testing machine with a press speed of 5 mm/minute. Loading and unloading forces were recorded on deflections of 0.5; 1; and1.5 mm. Statistical tests of differences among groups were carried out by ANOVA analysis (p-value ≤ 0.05) and post-hoc analysis with T-test. There were significant differences in the loading and unloading forces recorded on deflections of 0.5; 1; and 1.5 mm; except for deflections of 0.5 mm of the SS and nickel-titanium wires. The wire deflection force fromthe lowest to the highest was CuNiTi wire, nickel-titanium wire, TMA wire, and stainless-steel wire.
随着正畸领域技术的发展,产生了一些具有不同偏转能力的正畸线。加载力是将正畸金属丝放入托槽(激活)所需的力。卸荷力是正畸金属丝移动牙齿(使牙齿失活)所产生的力。三点弯曲法挠度试验是测定正畸丝激活和失活力大小的常用方法。不锈钢(SS)、镍钛(NiTi)、铜镍钛(CuNiTi)和β钛(TMA)是常用的金属丝类型。本研究旨在比较0.016 x 0.022英寸尺寸的SS、NiTi、CuNiTi和TMA正畸丝在载荷-挠度图上的载荷和卸载挠度试验力。这是一项共16根尺寸为0.016 x 0.022英寸的SS、NiTi、CuNiTi和TMA正畸金属丝的实验室实验研究。这组人是根据材料的类型来划分的。挠度试验采用万能试验机,压速为5mm /分钟。在挠度为0.5时记录加载和卸载力;1;and1.5毫米。组间差异的统计检验采用方差分析(p值≤0.05),事后分析采用t检验。在挠度为0.5时记录的加载和卸载力有显著差异;1;1.5 mm;除了SS线和镍钛线的0.5 mm偏转。线材挠曲力由低到高依次为CuNiTi丝、镍钛丝、TMA丝、不锈钢丝。
{"title":"Deflection test on different orthodontic wire materials sized 0.016 x 0.022 inches","authors":"Harris Gadih Pratomo, Endah Mardiati, E. S. Soemantri, I. A. Evangelina","doi":"10.22146/majkedgiind.31236","DOIUrl":"https://doi.org/10.22146/majkedgiind.31236","url":null,"abstract":"The development of technology in orthodontic field produces some orthodontic wires that have different deflection abilities. Loading force is the force needed to place an orthodontic wire in bracket slot (activation). Unloading force is the force produced by an orthodontic wire to move tooth (deactivation). Deflection test with three-point bending technique is a technique that is often used to determine the magnitude of the activation and deactivation force of orthodontic wire. Stainless steel (SS), nickel titanium (NiTi), copper nickel titanium (CuNiTi), and beta titanium (TMA), are the types of frequently used wires. This study aimed to compare loading and unloading force on the deflection test of SS, NiTi, CuNiTi, and TMA orthodontic wires sized 0.016 x 0.022 inch on the load-deflection graph. This is a laboratoryexperimental research on a total of 16 pieces of SS, NiTi, CuNiTi, and TMA orthodontic wires sized 0.016 x 0.022 inches. The group was divided based on the type of material. The deflection test was performed using a universal testing machine with a press speed of 5 mm/minute. Loading and unloading forces were recorded on deflections of 0.5; 1; and1.5 mm. Statistical tests of differences among groups were carried out by ANOVA analysis (p-value ≤ 0.05) and post-hoc analysis with T-test. There were significant differences in the loading and unloading forces recorded on deflections of 0.5; 1; and 1.5 mm; except for deflections of 0.5 mm of the SS and nickel-titanium wires. The wire deflection force fromthe lowest to the highest was CuNiTi wire, nickel-titanium wire, TMA wire, and stainless-steel wire.","PeriodicalId":31262,"journal":{"name":"Majalah Kedokteran Gigi Indonesia","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84476368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of cervical vertebral maturity and teeth calcification stages in children with cleft lip and palate 唇腭裂患儿颈椎成熟度与牙齿钙化阶段的关系
Pub Date : 2019-09-19 DOI: 10.22146/majkedgiind.31875
Sandy Pamadya, A. Azhari, R. Firman
Cleft lip and palate are the most common craniofacial anomalies in Indonesia. Recent publications report that there was delayed skeletal and dental age in cleft lip and palate patients. Panoramic and lateral cephalometric radiograph to evaluate growth and development through skeletal and dental age is still rarely used. The research aimed to determine the correlation between cervical vertebral maturation and teeth calcification stages in children aged 7 to 16 years old with cleft lip and palate in Unpad Dental Hospital. The research design was analytic correlation and the sample was selected using purposive sampling cross-sectional using secondary data panoramic and lateral cephalometric radiograph. The scores of cervical maturation and teeth calcification stages were then analyzed statistically using SPSS version 16. Spearman coefficient of rank correlation test showed strong correlation between cervical vertebral maturation and teeth calcification stages on all teeth, with the highest rs score was secondary molar (0.734) and p value 0.000 The conclusion of this research is that there is a strong correlation between cervical vertebral maturation and teeth calcification stages in children aged 7 to 16 years old with cleft lip and palate.
唇腭裂是印尼最常见的颅面畸形。最近的出版物报道,有延迟骨骼和牙齿年龄的唇腭裂患者。全景和侧位头颅x线片通过骨骼和牙齿年龄来评估生长发育仍然很少使用。本研究旨在确定Unpad牙科医院7 ~ 16岁唇腭裂儿童颈椎成熟与牙齿钙化阶段的相关性。研究设计为分析相关性,样本选择采用目的性采样横断面,采用二次资料,全景和侧位头颅x线片。采用SPSS 16对颈椎成熟和牙齿钙化阶段评分进行统计分析。Spearman秩相关系数检验显示,所有牙齿的颈椎成熟度与牙齿钙化阶段均有较强的相关性,rs评分最高的是第二磨牙(0.734),p值为0.000。本研究结论为7 ~ 16岁唇腭裂患儿颈椎成熟度与牙齿钙化阶段有较强的相关性。
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引用次数: 0
The relationship between salivary secretion and taste sensitivity level in the elderly 老年人唾液分泌与味觉敏感水平的关系
Pub Date : 2019-09-06 DOI: 10.22146/majkedgiind.36903
Fimma Naritasari, D. Agustina, S. Supriatno
The increasing population of the elderly has an impact on health problems, including an increase of oral problems. One of the common oral problems is dry mouth that possibly disrupts gustatory function. The aim of this study was to investigate the relationship between salivary secretion and taste sensitivity level in the elderly. This study was a cross sectional study for the elderly population of Daerah Istimewa Yogyakarta/The Special Region of Yogyakarta (DIY) Province, Indonesia. This study consisted of interview, clinical examination, measurement of salivary secretion (sialometry) and taste sensitivity level using chemical gustometry method. Salivary secretion data were described in ml/ min. The measurement of taste sensitivity level was performed using 4 different substances: sweet (sucrose), salty (NaCl), sour (citric acid) and bitter (quinidine sulphate) with 4 different concentrations for each flavor. Four score was given if the respondent recognized the lowest concentration of the substance and 0 score was provided when all concentrations were failed to be tasted. Total score for test sensitivity level was scaled from 0 to 16. Salivary secretion data and taste sensitivity level data were analyzed by Spearman correlation test to determine the correlation between both variables. There were 103 subjects (70 women and 33 men) with the age mean of 65.61 years old, participating in this study. The mean of the sweet taste level was 2.81, 3.32 for salty taste, 3.69 for sour taste and 2.98 for bitter taste. Total taste sensitivity level mean was 12.80 out of 16. The measurements of unstimulated whole saliva showed a mean value of 0.170 ml/min with the majority of subjects having normal salivary flow. The Spearman correlation test results showed r= -0.078 with p >0.05 that indicated no correlation. We concluded that there was no relationship between salivary secretion and taste sensitivity level in the elderly.
老年人口的增加对健康问题产生了影响,包括口腔问题的增加。口腔干燥是常见的口腔问题之一,它可能会干扰味觉功能。本研究的目的是探讨老年人唾液分泌与味觉敏感水平的关系。本研究是一项针对印度尼西亚日惹省(DIY)特区Daerah Istimewa Yogyakarta老年人口的横断面研究。本研究包括访谈、临床检查、用化学味觉法测定唾液分泌量和味觉敏感水平。唾液分泌数据以ml/ min为单位进行描述。味觉敏感性水平的测量采用4种不同的物质:甜味(蔗糖)、咸味(NaCl)、酸味(柠檬酸)和苦味(硫酸奎尼丁),每种风味有4种不同的浓度。如果被调查者认识到物质的最低浓度,则打4分,如果所有浓度都未能品尝,则打0分。测试敏感性水平的总得分从0到16。唾液分泌数据和味觉敏感水平数据采用Spearman相关检验进行分析,以确定两者之间的相关性。本研究共纳入103例受试者,其中女性70例,男性33例,平均年龄65.61岁。甜味水平均值为2.81,咸味为3.32,酸味为3.69,苦味为2.98。总味觉敏感水平平均为12.80分(满分16分)。未受刺激的全唾液流量平均值为0.170 ml/min,大多数受试者唾液流量正常。Spearman相关检验结果为r= -0.078, p >0.05,无相关性。我们得出结论,老年人唾液分泌与味觉敏感水平之间没有关系。
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引用次数: 0
Effect of β-carotene patch application on gingival crevicular fluid volume after repeated periapical radiographic exposure 应用β-胡萝卜素贴片对反复根尖周造影后龈沟液容量的影响
Pub Date : 2019-09-06 DOI: 10.22146/majkedgiind.42485
Faluthia Arini Puspitaningrum, Rurie Ratna Shantiningsih, Ryna Dwi Yanuaryska
Free radicals generated during ionization process of X-rays can damage biological tissues. Radiation exposure to gingival sulcus area will damage endothelial cells and increase permeability of blood vessels under sulcular and junctional epithelium. That inflammation will increase gingival crevicular fluid (GCF) volume. Repeated periapical radiographs often occurs due to the unfulfillment of quality assurance and leads to an increase amount of radiation dose received by the patient. Previous studies have shown that β-carotene mucoadhesive gingival patch can penetrate mucous membrane and provide protection against radiation by reducing the number of gingival epithelial cells micronuclei. The aims of this study was to observe β-carotene mucoadhesive gingival patch effect in GCF volume from patient exposed to repeated periapical radiographs. We recruited 10 participants from patients who receive repeated periapical radiographs in instalation of dentomaxillofacial radiology, Prof Soedomo dental and oral hospital Faculty of Dentistry UGM. The teeth of the subjects are divided into control and treatment group. β-carotene mucoadhesive gingival patch was applied to treatment group. GCF was collected using an absorbing paper strip before and after exposure, then measured bysliding caliper. Paired T-test showed significant differences (p<0.05) between GCF volume before and after radiographic exposure in each group. Independent T-test showed significant differences (p<0.05) of GCF volume between control and treatment group. Conclusion of this study is β-carotene mucoadhesive gingival patch significantly reduce GCF volume after repeated periapical radiographic exposure.
x射线电离过程中产生的自由基会损伤生物组织。辐射暴露于龈沟区会损伤内皮细胞,增加龈沟上皮和结上皮下血管的通透性。这种炎症会增加牙龈沟液(GCF)的体积。由于质量保证不到位,经常出现重复的根尖周x线检查,导致患者接受的放射剂量增加。已有研究表明,β-胡萝卜素黏附牙龈贴片通过减少牙龈上皮细胞微核的数量来穿透粘膜,起到抗辐射的作用。本研究的目的是观察β-胡萝卜素黏附牙龈贴片对反复根尖周x线片患者GCF体积的影响。我们招募了10名参与者,这些患者接受了反复的根尖周x线摄影,以安装牙颌面放射学,Soedomo牙科和口腔医院牙科学院UGM。将受试者的牙齿分为对照组和治疗组。治疗组采用β-胡萝卜素黏附龈贴。在暴露前后用吸光纸条收集GCF,然后用滑动卡尺测量。配对t检验显示,各组放射照射前后GCF体积差异有统计学意义(p<0.05)。独立t检验显示对照组与治疗组GCF体积差异有统计学意义(p<0.05)。结论:β-胡萝卜素黏附牙龈贴片在根尖周反复暴露后可显著减少GCF体积。
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引用次数: 1
Physiological maturation stage of cervical vertebrate index in cleft lip/palate and non-cleft lip/palate patients 唇腭裂与非唇腭裂患者颈椎指数的生理成熟阶段
Pub Date : 2019-09-06 DOI: 10.22146/majkedgiind.28356
Wenti Komala, Endah Mardiati, E. S. Soemantri, Isnaniah Malik
Cleft lip and palate is one of the most common congenital anomalies. Cleft lip and palate patients encounter growth problems in lip and palate area, although their overall growth and development remains unknown. Cervical vertebral maturation are indicators of physiological maturation used in interceptive treatment and orthognathic surgery. The present study aims to determine physiological maturation stage of cervical vertebrae maturation index in cleft andnon-cleft patients. Lateral cephalogram of 26 cleft patients and 27 non-cleft patients with a range of chronological age from 8-16 years old were involved. The cervical vertebrae maturation were analyzed in six stages of cervical vertebrae maturation method of Hassel and Farman. Data were analyzed using t-test (p≤ 0.05). The result shows that physiologicalmaturation stage of cervical vertebrae maturation index in cleft and non-cleft patients has no significant difference in stage acceleration (p= 0.38), stage transition (p= 0.41) and deceleration (p= 0.39). Likewise, there is no significant difference in physiological maturation stage of cervical vertebrae maturation index between cleft and non-cleft patients. 
唇腭裂是最常见的先天性畸形之一。唇腭裂患者会遇到唇腭裂区域的生长问题,尽管他们的整体生长发育尚不清楚。颈椎成熟是用于截流治疗和正颌手术的生理成熟指标。本研究旨在确定腭裂和非腭裂患者颈椎成熟指数的生理成熟阶段。对年龄8 ~ 16岁的26例唇裂患者和27例非唇裂患者进行侧位脑电图分析。分析了Hassel和Farman颈椎成熟法的6个阶段。数据分析采用t检验(p≤0.05)。结果表明,裂、非裂患者的颈椎成熟指数生理成熟阶段在加速(p= 0.38)、过渡(p= 0.41)和减速(p= 0.39)方面无显著差异。同样,裂与非裂患者的颈椎成熟指数生理成熟阶段也无显著差异。
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引用次数: 2
Rapid enamel deposition on Sprague Dawley after nano calcium supplementation during pregnancy 妊娠期补充纳米钙后Sprague Dawley牙釉质快速沉积
Pub Date : 2019-09-06 DOI: 10.22146/majkedgiind.37412
H. Sitosari, A. Jonarta, Y. A. Sumiwi, T. Haniastuti
Calcium is one of the most important minerals needed during hard tissue development. The preparation of this material into nano-sized particle is carried out to enhance the bioavailability and distribution of calcium in the body. Lack of calcium during odontogenesis causes defect in enamel such as hypoplasia and hypomineralization. During amelogenesis, after secretion of organic matrices, enamel mineralization will start in the presence of calcium. The objective of this study was to determine the effect of nano calcium supplementation during pregnancy on enamel development. In this study, 3-month-old female Sprague Dawley were mated and divided into three groups: nano calcium group (A), micro calcium group (B), and negative control group (C). The treatment was started on day 1 of pregnancy to day 1 after birth by intragastric administration method. The mandibles of 6 pups from each group were collected and stained with hematoxylin and eosin. Examination was conducted using microscope. Enamel deposition was measured using Optilab Image Raster® and the data collected was analyzed using t-test. Histological section of mandibular right first molar on Sprague Dawley newborn pups showed that enamel was observed on day 1 after birth but only on the group treated with nano calcium and micro calcium. Statistical analysis performed showed that the difference between the two groups was significant (p<0.05). From this study it can be concluded that the administration of nano calcium during pregnancy leads to rapid enamel deposition on Sprague Dawley pups.
钙是硬组织发育过程中最重要的矿物质之一。将该材料制备成纳米级颗粒是为了提高钙在体内的生物利用度和分布。牙形成过程中缺乏钙会导致牙釉质缺陷,如发育不全和低矿化。在成釉过程中,在有机基质分泌后,牙釉质矿化将在钙的存在下开始。本研究的目的是确定在怀孕期间补充纳米钙对牙釉质发育的影响。本研究选取3月龄雌性Sprague Dawley交配,将其分为纳米钙组(A)、微钙组(B)和阴性对照组(C) 3组,从妊娠第1天至出生后第1天开始灌胃给药。每组取6只幼崽下颌骨进行苏木精和伊红染色。显微镜下检查。使用Optilab Image Raster®测量牙釉质沉积,并使用t检验分析收集的数据。新生犬下颌骨右第一磨牙的组织学切片显示,出生后第1天出现牙釉质,但仅纳米钙和微钙处理组出现牙釉质。经统计学分析,两组间差异有统计学意义(p<0.05)。本研究表明,妊娠期给予纳米钙可导致犬的牙釉质快速沉积。
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Majalah Kedokteran Gigi Indonesia
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