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The Effect of Health Education with Flashcard Media on Improvement of Knowledge and Reduction of Anxiety Degree in Adolescents Primigravida 用抽认卡媒介进行健康教育对初潮青少年知识提高和焦虑程度的影响
Pub Date : 2020-04-30 DOI: 10.29313/GMHC.V8I1.5192
Dwie Yunita Baska, T. Madjid, P. Idjradinata
The education about the reproductive health of pregnancy is needed to increase knowledge and reduce anxiety in adolescent primigravida, one of them is by conducting flashcard media. Flashcards are pictorial media in the form of cards that have words; it’s proven to be able to create fun learning, attracts attention, and stimulates critical thinking. The purpose of the study was to analyze the effect of education with flashcard media on knowledge and anxiety degree in adolescent primigravidas. The research method used in this study was a one-group pretest-posttest quasi-experimental design. The number of samples as many as 30 people (<20 years old) at Sawah Lebar Public Health Center and Padang Serai Public Health Center in Bengkulu city from May to July 2018, by using consecutive sampling. The data of this study obtained from pretest and posttest questionnaires of knowledge, and Zung Self-rating Anxiety Scale (ZSAS), Shapiro-Wilk, Wilcoxon, and chi-square test statistics. The results showed a significant increase in knowledge before and after the intervention of p value=0.001 (p<0.05), an increase in the average score of knowledge of series one card amounts to 35.0% and knowledge of series 2–3 card amounted to 30%. A significant decrease in anxiety degree of 9.2% after the treatment (p<0.05). In conclusion, flashcards can increase knowledge and reduce the anxiety of adolescents primigravida mothers so that health workers use this educational approach appropriately. PENGARUH EDUKASI KESEHATAN DENGAN MEDIA FLASHCARD TERHADAP PENINGKATAN PENGETAHUAN DAN PENURUNAN DERAJAT KECEMASAN PADA PRIMIGRAVIDA REMAJA The education about the reproductive health of pregnancy is needed to increase knowledge and reduce anxiety in adolescent primigravida, one of them is by conducting flashcard media. Flashcards are pictorial media in the form of cards that have words; it’s proven to be able to create fun learning, attracts attention, and stimulates critical thinking. The purpose of the study was to analyze the effect of education with flashcard media on knowledge and anxiety degree in adolescent primigravidas. The research method used in this study was a one-group pretest-posttest quasi-experimental design. The number of samples as many as 30 people (<20 years old) at Sawah Lebar Public Health Center and Padang Serai Public Health Center in Bengkulu city from May to July 2018, by using consecutive sampling. The data of this study obtained from pretest and posttest questionnaires of knowledge, and Zung Self-rating Anxiety Scale (ZSAS), Shapiro-Wilk, Wilcoxon, and chi-square test statistics. The results showed a significant increase in knowledge before and after the intervention of p value=0.001 (p<0.05), an increase in the average score of knowledge of series one card amounts to 35.0% and knowledge of series 2–3 card amounted to 30%. A significant decrease in anxiety degree of 9,2% after the treatment (p<0.05). In conclusion, flashcards can increase knowledge and red
需要开展关于怀孕生殖健康的教育,以增加初潮少女的知识,减少她们的焦虑,其中一种方式是使用抽认卡媒体。抽认卡是一种有文字的卡片形式的图形媒体;事实证明,它能够创造有趣的学习,吸引注意力,并激发批判性思维。本研究旨在分析抽认卡媒介教育对初潮青少年知识和焦虑程度的影响。本研究采用一组前测后测准实验设计。2018年5月至7月在明古鲁市Sawah Lebar公共卫生中心和Padang Serai公共卫生中心采用连续抽样的方法,样本数量多达30人(20岁以下)。本研究数据来源于知识前测和后测问卷、Zung焦虑自评量表(ZSAS)、Shapiro-Wilk、Wilcoxon和卡方检验统计。结果显示,干预前后知识水平显著提高,p值=0.001 (p<0.05),系列1卡知识平均得分提高35.0%,系列2-3卡知识平均得分提高30%。治疗后焦虑程度显著降低9.2% (p<0.05)。总之,抽认卡可以增加初潮少女母亲的知识,减少她们的焦虑,以便保健工作者恰当地使用这种教育方法。为了增加初潮青少年的生殖健康知识和减少焦虑,需要进行有关怀孕生殖健康的教育,其中一种方法是进行抽认卡媒体。抽认卡是一种有文字的卡片形式的图形媒体;事实证明,它能够创造有趣的学习,吸引注意力,并激发批判性思维。本研究旨在分析抽认卡媒介教育对初潮青少年知识和焦虑程度的影响。本研究采用一组前测后测准实验设计。2018年5月至7月在明古鲁市Sawah Lebar公共卫生中心和Padang Serai公共卫生中心采用连续抽样的方法,样本数量多达30人(20岁以下)。本研究数据来源于知识前测和后测问卷、Zung焦虑自评量表(ZSAS)、Shapiro-Wilk、Wilcoxon和卡方检验统计。结果显示,干预前后知识水平显著提高,p值=0.001 (p<0.05),系列1卡知识平均得分提高35.0%,系列2-3卡知识平均得分提高30%。治疗后焦虑程度显著降低9.2% (p<0.05)。总之,抽认卡可以增加初潮少女母亲的知识,减少她们的焦虑,以便保健工作者恰当地使用这种教育方法。
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引用次数: 2
A Comparative Evaluation of Community Periodontal Index (CPI) and the Presence of Nicotine Stomatitis among Smokers after Oral Hygiene Instruction 吸烟者接受口腔卫生指导后社区牙周指数(CPI)与尼古丁性口炎的比较评价
Pub Date : 2020-04-30 DOI: 10.29313/GMHC.V8I1.5915
M. M. Damayanti, Y. Kharisma, Fajar Awaliya Yulianto, S. Rahimah, W. Maharani, M. Rachmawati, H. Sastramihardja, Muhammad Alief Abdul ‘Aziiz, Muhammad Ilham Halim
Smoking can cause periodontal disease as well as lesions in the oral mucosa. Nicotine stomatitis is inflammation caused by heat stimuli injury on the hard and soft palate of the oral cavity; smokers commonly suffer from this condition. Knowledge of how oral hygiene affects the health of dental and oral cavity. The purpose of this study was to describe the differences in community periodontal index (CPI) and nicotine stomatitis in smokers after oral hygiene instruction. The study subjects were 54 men who have a history of active smoking for more than five years. The experiment was carried out in the Biomedical Laboratory of Faculty of Medicine Universitas Islam Bandung in September 2018–January 2019. Dental examination initiated before and after dental health instructions. CPI and nicotine stomatitis tests performed on all subjects by dentists using dental instruments. After six weeks of information about oral hygiene, all subjects re-examined. The results show that there is a statistically significant difference in the average CPI value in smokers before and after dental instruction with a p value<0.001 (p≤0.05). In contrast, the condition of nicotine stomatitis remains the same. CPI value influenced by oral and dental hygiene showed that dental health instruction is very effective. However, stomatitis has not healed as long as the cause is not eliminated. EVALUASI KOMPARATIF COMMUNITY PERIODONTAL INDEX (CPI) DAN STOMATITIS NIKOTIN DI KALANGAN PEROKOK SETELAH INSTRUKSI KEBERSIHAN MULUT Merokok dapat menyebabkan penyakit pada periodontal maupun lesi pada mukosa mulut. Stomatitis nikotin merupakan inflamasi yang disebabkan oleh panas yang terdapat pada palatum keras dan lunak; perokok umumnya menderita kondisi ini. Pengetahuan mengenai tata cara kebersihan mulut memengaruhi kesehatan gigi dan rongga mulut. Tujuan penelitian ini menilai perbedaan community periodontal index (CPI) dan stomatitis nikotin pada perokok setelah instruksi kebersihan mulut. Subjek penelitian adalah 54 pria yang memiliki riwayat merokok aktif selama lebih dari lima tahun. Penelitian dilakukan di Laboratorium Biomedik, Fakultas Kedokteran, Universitas Islam Bandung pada bulan September 2018–Januari 2019. Pemeriksaan dental dilakukan sebelum dan setelah instruksi kesehatan gigi. Pemeriksaan CPI dan stomatitis nikotin dilakukan kepada seluruh subjek oleh dokter gigi menggunakan instrumen gigi. Setelah enam minggu mendapatkan penyuluhan mengenai kebersihan mulut, seluruh subjek diperiksa kembali. Hasil penelitian menunjukkan bahwa terdapat perbedaan bermakna secara statistik nilai CPI rerata pada perokok sebelum dengan setelah dilakukan instruksi kesehatan gigi dengan p<0,001 (p≤0,05). Sebaliknya, kondisi stomatitis nikotin tetap sama. Nilai CPI dipengaruhi oleh kebersihan gigi dan mulut sehingga instruksi kesehatan gigi sangat efektif. Akan tetapi, stomatitis tidak dapat sembuh selama penyebabnya tidak dihentikan.
吸烟会引起牙周病和口腔黏膜损伤。尼古丁性口炎是热刺激损伤口腔软硬腭引起的炎症;吸烟者通常患有这种疾病。了解口腔卫生如何影响牙齿和口腔健康。本研究旨在探讨吸烟者在接受口腔卫生指导后社区牙周指数(CPI)和尼古丁性口炎的差异。研究对象是54名有5年以上吸烟史的男性。实验于2018年9月至2019年1月在万隆伊斯兰大学医学院生物医学实验室进行。在牙齿健康指示前后进行牙齿检查。由牙医使用牙科器械对所有受试者进行CPI和尼古丁口炎测试。在提供口腔卫生信息六周后,所有受试者再次接受检查。结果显示,吸烟者牙科指导前后的平均CPI值差异有统计学意义,p值<0.001 (p≤0.05)。相比之下,尼古丁性口炎的情况保持不变。口腔卫生对CPI值的影响表明,口腔卫生指导是有效的。然而,只要病因不消除,口腔炎就不会愈合。社区牙周病指数(CPI)的评价:口腔炎患者的牙周病指数。口腔炎;口腔炎;口腔炎;Perokok umumnya menderita kondisi ini。Pengetahuan mengenai tata cara kebersihan mulut menengaruhi kesehatan gigi dan rongga mulut。牙周病指数(CPI)与口腔炎的相关性研究:牙周病指数(CPI)与口腔炎的相关性研究。科目penelitian adalah 54 pria yang memoriliki riwayat merokok akif selama lebih dari lima tahun。Penelitian dilakukan di Laboratorium Biomedik, Fakultas Kedokteran,伊斯兰大学万隆市,2018年9月- 2019年1月。penemeriksaan dental dilakukan sebelum dan setelah indksi kesehatan gigi。Pemeriksaan CPI和口腔炎,尼古丁,dilakukan, kepada, seururk,受试者,oleh, dokter, gigi, menggunakan,仪器,gigi。Setelah enam minggu mendapatkan penyuluhan mengenai kebersihan mulut, seluruh subject jek diperiksa kembali。Hasil penelitian menunjukkan bahwa terdapat perbedaan和bermakna secara统计数据nilai CPI rerata pada perokok sebelum dengan setelah dilakukan indicksi keshatanan gigi dengan p< 0.001 (p≤0.05)。烟碱性口腔炎。Nilai CPI dipengaruhi oleh kebersihan gigi danmulutingingingi gigi sangatektif。口腔炎,口腔炎,口腔炎,口腔炎,口腔炎。
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引用次数: 0
Dermatoglyphics Pattern on Breast Cancer Patients in Dharmais Cancer Hospital 癌症医院癌症乳腺癌患者皮纹图谱
Pub Date : 2020-04-30 DOI: 10.29313/GMHC.V8I1.4470
Faras Qodriyyah Sani, Mirfat Mirfat, I. Iskandar
Dermatoglyphics is a study of the epidermal ridge in fingers, palms, soles, toes, and formed under genetic control at the beginning of the development of the fetus around 6–7 weeks and continues until 20–21 weeks. The development of the breast begins in a 6-week-old fetus in the epidermis and at the bottom of the mesenchyme. The development of the finger ridges and breast occurs at six weeks of gestation, and the abnormal genomes can be detected at this period and observed through dermatoglyphics. The purpose of this study was to determine the dermatoglyphic patterns of breast cancer patients in Dharmais Cancer Hospital from 12 December 2018 to 1 January 2019. The study was a descriptive study with a purposive sampling method for the determination of the sample. The quantitative data collected using questionnaires while the prints of dermatoglyphic patterns were from the fingertips of the respondent. From 100 respondents, the left-hand fingers and right-hand fingers dominated by radial loop pattern with the most significant percentage on the middle finger 62% and 77%, respectively. While the ring finger dominated by the plain whorl pattern 43%. In conclusion, the dermatoglyphics pattern on breast cancer patients in Dharmais Cancer Hospital dominated by a radial loop pattern. POLA DERMATOGLIFI TANGAN PASIEN KANKER PAYUDARA DI RUMAH SAKIT KANKER DHARMAIS Dermatoglifi merupakan ilmu yang mempelajari tentang pola sulur pada jari, telapak tangan, telapak kaki, dan jari kaki yang terbentuk di bawah kontrol genetik pada awal perkembangan usia janin sekitar 6–7 minggu serta terus berkembang sampai usia 20–21 minggu. Perkembangan payudara dimulai pada janin berusia 6 minggu dalam bentuk gumpalan padat yang berada di epidermis dan di bagian bawah mesenkim. Perkembangan sulur dermal dan payudara terjadi pada usia kehamilan enam minggu dan genom tidak abnormal dapat dideteksi pada periode ini dan dapat teramati melalui dermatoglifi. Tujuan penelitian ini mengetahui pola dermatoglifi pada pasien kanker payudara di Rumah Sakit Kanker Dharmais dari tanggal 12 Desember 2018 hingga 1 Januari 2019. Penelitian ini merupakan studi deskriptif dengan metode purposive sampling untuk penentuan sampel. Data kuantitatif diperoleh dengan menggunakan kuesioner, sedangkan cetakan pola dermatoglifi berasal dari ujung jari tangan responden. Dari 100 responden, jari tangan kiri dan jari tangan kanan didominasi oleh pola radial loop dengan persentase terbesar pada jari tengah sebesar 62% dan 77% masing-masing. Sementara jari manis didominasi oleh pola plain whorl sebesar 43%. Simpulan, pola dermatoglifi pada pasien kanker payudara di Rumah Sakit Kanker Dharmais didominasi oleh pola radial loop .
皮肤纹是对手指、手掌、脚底、脚趾的表皮脊的研究,在基因控制下形成于胎儿发育之初,大约在6-7周左右,并持续到20-21周。乳房的发育始于6周大的胎儿表皮和间质底部。手指脊和乳房的发育发生在妊娠6周,在这一时期可以检测到异常基因组,并通过皮肤印记观察。本研究的目的是确定2018年12月12日至2019年1月1日在Dharmais肿瘤医院的乳腺癌患者的皮肤印记模式。本研究为描述性研究,采用有目的的抽样方法确定样本。定量数据采用问卷调查的方式收集,而纹纹图案的指纹则来自被调查者的指尖。在100名被调查者中,左手手指和右手手指以径向环状图案为主,其中中指的比例分别为62%和77%。而无名指则以普通圆环型占43%。综上所述,达摩肿瘤医院乳腺癌患者皮肤纹以放射状环状纹为主。POLA DERMATOGLIFI TANGAN PASIEN KANKER PAYUDARA DI RUMAH SAKIT KANKER DHARMAIS DERMATOGLIFI merupakan ilmu yang mempelajari tentang POLA sulur pada jari, telapak TANGAN, telapak kaki, dan jari kaki yang terbentuk DI bawah控制基因pada awal perkembangan usia janin sekitar 6-7 minggu serta terus berkembang sampai usia 20-21 minggu。【中文译文】【中文译文】【中文译文】【中文译文】【中文译文】Perkembangan sulsulderderderudara, terjadi, pagadusia, kehamilan, minggu, dangengenteak,异常,dideteksi, pagadera,周期,pagatteramati,千层皮肤。Tujuan penelitian ini mengetahui pola dermatoglifi pada pasen kanker payudara di Rumah Sakit kanker Dharmais dari tanggal 2018年12月12日至2019年1月1日。Penelitian ini merupakan的研究描述了一种有目的的抽样方法,并对Penelitian merupakan样本进行了分析。数据kuantitatif diperoleh dengan menggunakan kuesioner,而cetakan普拉dermatoglifi berasal达里语岬jari tangan responden。Dari 100响应,jari tangan kiri dan jari tangan kanan didominasi oleh pola径向环denengan表示,terbesar pada jari tengah sebesar 62% dan 77% masing-masing。Sementara jari manis didominasi oleh pola平原全球sebesar 43%。Simpulan, pola dermatoglifi pada pasien kanker payudara di Rumah Sakit kanker Dharmais didominasi oleh pola radial loop。
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引用次数: 0
Comparative Study Gallbladder Contractility Index Using Ultrasound in Patients with and without Liver Cirrhosis 超声对肝硬化和非肝硬化患者胆囊收缩指数的比较研究
Pub Date : 2020-04-30 DOI: 10.29313/GMHC.V8I1.3744
H. Soekersi, Leni Santiana, Fetty Fatmawaty
Liver cirrhosis leads to impairment of gallbladder contractility resulting in bile stasis and facilitate the development of gallstones that will aggravate the clinical symptoms of the patients. The gallbladder contractility index is an indicator of gallbladder motility measured using ultrasound as the radiological choice of modality. This study aims to determine differences in the gallbladder contractility index using ultrasound in patients with and without liver cirrhosis. This study was an observational study of comparative analytic with cross-sectional design with sampling conducted by consecutive admissions sampling at Dr. Hasan Sadikin General Hospital Bandung from December 2017 to February 2018. Statistical analysis than performed by using an independent t test to find out the difference of gallbladder contractility index in patients with and without liver cirrhosis. A total of 22 subjects, 12 men, 10 women, with the youngest 37 years old and the oldest 70 years old. The result of the study was obtained mean fasting gallbladder volume (35.56±22.16 mL) and postprandial (21.25±16.08 mL) in patients with liver cirrhosis higher than without liver cirrhosis with mean fasting gallbladder volume (16.50±4.14 mL) and postprandial (5.44±2.10 mL). The average gallbladder contractility index on patients with liver cirrhosis (41.64±24.52%) smaller than without liver cirrhosis (66.73±9.19%). The result of the statistical test showed that there was a significant difference in the gallbladder contractility index on patients with liver cirrhosis than without liver cirrhosis (p=0.007, p≤0.05). In conclusion, there was a significant difference in the gallbladder contractility index that measured by using ultrasound between the patients with and without liver cirrhosis. PERBEDAAN INDEKS KONTRAKTILITAS KANDUNG EMPEDU MENGGUNAKAN ULTRASONOGRAFI PADA PENDERITA SIROSIS HATI DAN TANPA SIROSIS HATI Sirosis hati menyebabkan gangguan indeks kontraktilitas kandung empedu yang mengakibatkan stasis cairan empedu dan memudahkan kejadian batu empedu yang akan memperberat gejala klinis pasien. Indeks kontraktilitas kandung empedu merupakan indikator motilitas kandung empedu yang diukur menggunakan ultrasonografi (USG) sebagai modalitas pilihan radiologi. Penelitian ini bertujuan mengetahui perbedaan indeks kontraktilitas kandung empedu menggunakan ultrasonografi pada pasien sirosis hati dan tanpa sirosis. Penelitian ini menggunakan studi observasional analitik komparatif dengan rancangan cross-sectional dan pengambilan sampel dilakukan secara consecutive admissions sampling di RSUP Dr. Hasan Sadikin Bandung dari bulan Desember 2017 hingga Februari 2018. Uji statistik menggunakan independent t test . Subjek penelitian berjumlah 22, laki-laki 12 dan perempuan 10, serta usia termuda 37 tahun dan tertua 70 tahun. Hasil penelitian didapatkan volume rerata kandung empedu puasa (35,56±22,16 mL) dan pascaprandial (21,25±16,08 mL) pada pasien sirosis hati lebih besar daripada tanpa
肝硬化会导致胆囊收缩能力受损,导致胆汁淤积,并促进胆结石的发展,从而加重患者的临床症状。胆囊收缩指数是胆囊运动的指标,使用超声作为放射学模式的选择进行测量。本研究旨在确定肝硬化患者和非肝硬化患者胆囊收缩指数的差异。本研究是一项比较分析与横断面设计的观察性研究,2017年12月至2018年2月在万隆Hasan Sadikin医生综合医院通过连续入院抽样进行抽样。采用独立t检验进行统计分析,找出肝硬化患者和非肝硬化患者胆囊收缩指数的差异。共有22名受试者,12名男性,10名女性,其中最小的37岁,最大的70岁。研究结果显示,肝硬化患者的平均空腹胆囊容积(35.56±22.16 mL)和餐后胆囊容积(21.25±16.08 mL)高于非肝硬化患者的空腹胆囊容积平均值(16.50±4.14 mL)和饭后胆囊容积平均数(5.44±2.10 mL)。肝硬化患者平均胆囊收缩指数(41.64±24.52%)小于非肝硬化患者(66.73±9.19%)。统计检验结果显示,肝硬化患者胆囊收缩指数与非肝硬化患者相比有显著差异(p=0.007,p≤0.05)。肝硬化患者和非肝硬化患者的胆囊收缩指数在超声测量中存在显著差异。收缩指数转运指标,包括人类SIROS和非人类SIROS的超声活性肝硬化会导致肠道收缩指数受损,导致液体淤积,并促进结石排空,从而恶化患者的临床症状。受损组织收缩性指数是使用超声(USG)作为放射学选择模式测量的受损组织运动性的指标。本研究旨在找出肝硬化和非肝硬化患者使用超声检查的移情收缩指数的差异。这项研究使用了一项观察性分析研究,比较了2017年12月至2018年2月在RSUP Hasan Sadikin Bandung博士连续入院抽样的横断面计划和抽样。使用独立t检验的统计检验。22岁、12岁和10岁、37岁和70岁。研究结果显示,肝硬化患者的平均移情容量(35.56±22.16 mL)和帕随意性(21.25±16.08 mL)大于非肝硬化患者,平均移情容量为(16.50±4.14 mL)和帕随意性(5.44±2.10 mL)。肝硬化患者子宫共情收缩指数(41.64±24.52%)低于非肝硬化患者(66.73±9.19%)。统计结果显示,肝硬化患者和非肝硬化患者的子宫内膜收缩指数之间存在显著差异(p=0.007;p≤0.05)。简言之,在心脏性和非心脏性肝硬化患者中,使用USG的移情组织收缩指数之间存在显著差异。
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引用次数: 0
Relationship of Soil-transmitted Helminth and Enterobius vermicularis Infection with Anemic in Students in Aceh Besar 亚齐-贝萨尔地区土壤传播蠕虫和蛔虫感染与学生贫血的关系
Pub Date : 2020-04-30 DOI: 10.29313/GMHC.V8I1.4375
Faisal Heri, A. Depari, M. Panggabean
Helminthiasis is a disease caused by parasites in the form of worms, one of which is the type of soil-transmitted helminth (STH),   A. lumbricoides ,  T. trichiura ,  N. americanus , and A. duodenale  which infect humans through soil transmission.  Enterobius vermicularis  is the most common intestinal parasite in the whole world. Worms that live in the human intestine can cause malnutrition and anemic. This study aims to determine the relationship STH and  Enterobius vermicularis  infection with anemic of students in several elementary schools in Aceh Besar regency, Aceh province. This study was an analytical study using a cross-sectional study design conducted from May to November 2015. The sample consisted of the total sampling of 736 elementary school students, as well as using the inquiry method of Kato with stool specimens, cellophane tape anal swab, and hemoglobin. The correspondents who suffered from anemia and STH type helminthiasis, namely ancylostomiasis 7/7 students (100%, p=0.000); trichuriasis 30/58 students (51.7%, p=0.000) and 28 students not anemic (48.3%); and ascariasis 13/22 students (59.9%, p=0.002) and 9 students not anemic (41.1%). In enterobiasis infection, anemic students were 46/146 students (31.5%) and nonanemic students were 100 students (68.5%, p=0.634). In conclusion, all STH types related to the anemic status of the correspondent, and no correlation between anemic and infection of enterobiasis. HUBUNGAN INFEKSI SOIL-TRANSMITTED HELMINTH DAN ENTEROBIUS VERMICULARIS DENGAN ANEMIA PADA SISWA DI KABUPATEN ACEH BESAR PROVINSI ACEH Kecacingan adalah penyakit yang disebabkan oleh parasit berupa cacing, salah satunya jenis soil-transmitted helminth (STH), yaitu A. lumbricoides , T. trichiura , N. americanus , dan A. duodenale yang menginfeksi manusia melalui transmisi tanah. Enterobius vermicularis adalah parasit usus yang paling umum di seluruh dunia. Cacing yang hidup di usus manusia ini dapat menyebabkan kurang gizi dan anemia. Penelitian ini bertujuan mengetahui hubungan infeksi STH dan Enterobius vermicularis dengan anemia pada siswa sekolah dasar di Kabupaten Aceh Besar, Provinsi Aceh. Penelitian ini merupakan penelitian analitik menggunakan rancangan cross-sectional study yang dilaksanakan dari bulan Mei sampai November 2015. Sampel berupa total sampling 736 siswa sekolah dasar, serta menggunakan metode pemeriksaan Kato dengan spesimen feses, cellophane tape anal swab , dan hemoglobin. Koresponden yang menderita anemia dan kecacingan jenis STH, yaitu ancylostomiasis 7/7 siswa (100%, p=0,000); trichuriasis 30/58 siswa (51,7%; p=0,000) dan 28 siswa tidak anemia (48,3%); serta askariasis 13/22 siswa (59,9%; p=0,002) dan 9 siswa tidak anemia (41,1%). Pada infeksi enterobiasis, siswa yang anemia adalah 46/146 siswa (31,5%) dan tidak anemia 100 siswa (68,5%; p=0,634). Simpulan, semua kecacingan jenis STH berhubungan erat dengan status anemia pada koresponden, serta tidak terdapat hubungan antara anemia dan infeksi enterobi
蠕虫病是一种由蠕虫形式的寄生虫引起的疾病,其中一种是通过土壤传播感染人类的土壤传播蠕虫(STH)、蛔虫、鞭虫、美洲锥虫、十二指肠线虫。蛔虫是全世界最常见的肠道寄生虫。生活在人类肠道中的蠕虫会导致营养不良和贫血。本研究旨在确定STH和[UNK]蛔虫感染与亚齐省亚齐贝萨尔县几所小学学生贫血的关系。本研究是一项分析性研究,采用了2015年5月至11月进行的横断面研究设计。样本包括736名小学生的总样本,以及使用加藤的询问方法对粪便样本、玻璃纸胶带肛门拭子和血红蛋白进行的调查。贫血和STH型蠕虫病的通讯员,即钩虫病7/7名学生(100%,p=0.000);钩虫病30/58名学生(51.7%,p=0.000)和非贫血学生28名(48.3%);在肠病感染中,贫血学生为46/146名学生(31.5%),非贫血学生为100名学生(68.5%,p=0.634)。通过陆地传播感染人类的蛔虫、鞭虫、美洲猪笼草和十二指肠吸虫。蛔虫是世界上最常见的肠道寄生虫。生活在人类肠道中的猫可以减少刺激和贫血。本研究旨在了解亚齐省亚齐大首府小学STH感染与蛔虫和贫血之间的关系。本研究是一项分析性研究,采用了2015年5月至11月进行的横断面研究计划。样本是736名小学生的总样本,使用加藤的方法检查羊粪、玻璃纸胶带肛门拭子和血红蛋白样本。STH贫血和焦虑的通讯员,即钩虫病7/7名学生(100%,p=0.000);钩虫病30/58名学生(51.7%;p=0.000)和非贫血学生28名(48.3%);13/22名学生(59.9%;p=0.002)和9名非贫血学生(41.1%)。在肠病感染中,贫血的瞳孔为46/146(31.5%),而不是100(68.5%;p=0.634)。简介:STH的所有病变都与通讯员的贫血状况密切相关,贫血与肠病感染之间没有关系。
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引用次数: 2
Effect of Phaleria macrocarpa (Scheff.) Boerl Dry Extract to the Level of Malondialdehyde 大樱草的药效Boerl干提取物的丙二醛水平
Pub Date : 2020-04-30 DOI: 10.29313/gmhc.v8i1.5415
Meiyanti Meiyanti, E. Margo, Juni Chudri
Increased age causes an increase in degenerative diseases. Antioxidants in the body unable to neutralize the increased concentration of free radicals. The flesh of the  Phaleria macrocarpa (Scheff.) Boerl contains flavonoids which have antioxidant effects. At present, there are still very limited clinical trials of  Phaleria macrocarpa (Scheff.) Boerl. This study was an experimental pretest and posttest involving 30 healthy volunteers receiving glucose loads in November 2018–February 2019 in Jakarta. This study aimed to assess the antioxidant effect of   Phaleria macrocarpa (Scheff.) Boerl dry fruit extract in various dosage ranges. Subjects of this study aged 30–55 years. The data collection included anthropometric examination and malondialdehyde levels before and after administration of dry fruit extract doses of 62.5 mg, 125 mg, and 250 mg at 150 minutes after oral glucose induction. Data analysis using a paired t test with p<0.05. Decreased levels of malondialdehyde in the administration of  Phaleria macrocarpa (Scheff.) Boerl with a dose of 62.5 mg, 125 mg, and 250 mg by 40.9%, 22.9%, and 18.3% compared to the baseline malondialdehyde level (1,608 nmol/mL). Statistical analysis using a paired t test showed p=0.000 for all three doses compared with baseline levels. Dry fruit extract of Phaleria macrocarpa (Scheff.) Boerl has an antioxidant effect; the antioxidant effect of the extract is not directly proportional to the dose. EFEK ANTIOKSIDAN EKSTRAK KERING PHALERIA MACROCARPA (SCHEFF.) BOERL TERHADAP KADAR MALONDIALDEHID Pertambahan usia menyebabkan peningkatan penyakit degeneratif. Antioksidan dalam tubuh tidak mampu menetralkan peningkatan konsentrasi radikal bebas. Daging buah Phaleria macrocarpa (Scheff.) Boerl mengandung flavonoid mempunyai efek antioksidan. Saat ini masih sangat terbatas uji klinis Phaleria macrocarpa (Scheff.) Boerl. Penelitian ini merupakan uji eksperimental sebelum dan sesudah perlakuan pada 30 sukarelawan sehat yang diinduksi dengan glukosa yang dilaksanakan pada bulan November 2018–Februari 2019 di Jakarta. Penelitian ini bertujuan menilai efek antioksidan ekstrak kering buah Phaleria macrocarpa (Scheff.) Boerl dalam beberapa kisaran dosis yang diberikan. Subjek penelitian berusia 30–55 tahun. Pengumpulan data meliputi pemeriksaan antropometri serta kadar malondialdehid sebelum dan sesudah pemberian ekstrak kering dosis 62,5 mg, 125 mg, dan 250 mg pada menit 150 setelah dilakukan induksi glukosa oral. Analisis data menggunakan uji t berpasangan dengan p<0,05. Penurunan kadar malondialdehid pada pemberian ekstrak Phaleria macrocarpa (Scheff.) Boerl dosis 62,5 mg, 125 mg, dan 250 mg sebesar 40,9%, 22,9%, dan 18,3% dibanding dengan kadar malondialdehid sebelum pemberian (1.608 nmol/mL). Analisis statistik menggunakan uji t berpasangan didapatkan p=0,000 untuk ketiga dosis dibanding dengan kadar awal. Ekstrak kering buah Phaleria macrocarpa (Scheff.) Boerl mempunyai efek antioksidan; efek antioksidan ekstrak tidak ber
年龄的增长导致退行性疾病的增加。体内的抗氧化剂无法中和浓度增加的自由基。肉芽草(雪属)的肉Boerl含有具有抗氧化作用的类黄酮。目前,大阳泻(Phaleria macrocarpa)的临床试验还非常有限。Boerl。本研究是一项实验性前测和后测,涉及30名健康志愿者,于2018年11月至2019年2月在雅加达接受葡萄糖负荷。本研究旨在探讨大樱草的抗氧化作用。Boerl干果提取物在不同的剂量范围。研究对象年龄在30-55岁之间。数据收集包括在口服葡萄糖诱导后150分钟给药62.5 mg、125 mg和250 mg干果提取物前后的人体测量检查和丙二醛水平。数据分析采用配对t检验,p<0.05。降低丙二醛水平的管理在大樱草(Scheff。)与基线丙二醛水平(1,608 nmol/mL)相比,剂量为62.5 mg, 125 mg和250 mg的Boerl分别减少40.9%,22.9%和18.3%。使用配对t检验的统计分析显示,与基线水平相比,所有三种剂量的p=0.000。大玉兰(Phaleria macrocarpa)干果提取物Boerl具有抗氧化作用;提取物的抗氧化作用与剂量不成正比。黄芪抗黄芪抗黄芪抗黄芪抗黄芪抗黄芪BOERL TERHADAP KADAR MALONDIALDEHID Pertambahan usia menyebabkan peningkatan penyakit退化。Antioksidan dalam tubuh tidak mampu menetralkan peningkatan konsentrasi radikal bebas。大黄花(Scheff.)Boerl mengandung黄酮mempunyai efek抗黄酮类化合物。[3]中国植物学与植物学研究(英文)Boerl。Penelitian ini merupakan uji实验sebelum dan sesudah perlakan pada 30 sukarelawan sehat yang diinduksi dengan glukosa yang dilaksanakan pada bulan 2018年11月- 2019年2月在雅加达。Penelitian ini bertujuan menilei, efek antioksidan, ekstrak, kering, phellia macrocarpa (Scheff.)Boerl dalam beberapa kisaran dosis yang diberikan。科目penelitian berusia 30-55 tahun。本研究的数据为:ppppi、ppppi、ppppi、ppppi、ppppi、ppppi、ppppi、ppppi、ppppi、ppppi、ppppi、ppppi、ppppi、ppppi、ppppi、ppppi、ppppi、ppppi、ppppi。分析数据:蒙古纳坎乌吉,伯帕桑和登甘p< 0.05。Penurunan kadar malondialdehid padperberian ekstrak Phaleria macrocarpa (Scheff.)Boerl剂量62、5 mg、125 mg、250 mg, sebesar 40、9%、22、9%、18、3%,稀释登甘卡达尔丙二醛(1.608 nmol/mL)。分析统计孟古纳坎乌吉特·伯帕桑坎·迪达帕坎p= 1万例,克提加斯病在登甘卡达尔河的发病率。大水仙(Scheff.)Boerl mempunyay是一种抗氧剂;Efek抗氧化性抗氧化性抗氧化性丹参中毒。
{"title":"Effect of Phaleria macrocarpa (Scheff.) Boerl Dry Extract to the Level of Malondialdehyde","authors":"Meiyanti Meiyanti, E. Margo, Juni Chudri","doi":"10.29313/gmhc.v8i1.5415","DOIUrl":"https://doi.org/10.29313/gmhc.v8i1.5415","url":null,"abstract":"Increased age causes an increase in degenerative diseases. Antioxidants in the body unable to neutralize the increased concentration of free radicals. The flesh of the  Phaleria macrocarpa (Scheff.) Boerl contains flavonoids which have antioxidant effects. At present, there are still very limited clinical trials of  Phaleria macrocarpa (Scheff.) Boerl. This study was an experimental pretest and posttest involving 30 healthy volunteers receiving glucose loads in November 2018–February 2019 in Jakarta. This study aimed to assess the antioxidant effect of   Phaleria macrocarpa (Scheff.) Boerl dry fruit extract in various dosage ranges. Subjects of this study aged 30–55 years. The data collection included anthropometric examination and malondialdehyde levels before and after administration of dry fruit extract doses of 62.5 mg, 125 mg, and 250 mg at 150 minutes after oral glucose induction. Data analysis using a paired t test with p<0.05. Decreased levels of malondialdehyde in the administration of  Phaleria macrocarpa (Scheff.) Boerl with a dose of 62.5 mg, 125 mg, and 250 mg by 40.9%, 22.9%, and 18.3% compared to the baseline malondialdehyde level (1,608 nmol/mL). Statistical analysis using a paired t test showed p=0.000 for all three doses compared with baseline levels. Dry fruit extract of Phaleria macrocarpa (Scheff.) Boerl has an antioxidant effect; the antioxidant effect of the extract is not directly proportional to the dose. EFEK ANTIOKSIDAN EKSTRAK KERING PHALERIA MACROCARPA (SCHEFF.) BOERL TERHADAP KADAR MALONDIALDEHID Pertambahan usia menyebabkan peningkatan penyakit degeneratif. Antioksidan dalam tubuh tidak mampu menetralkan peningkatan konsentrasi radikal bebas. Daging buah Phaleria macrocarpa (Scheff.) Boerl mengandung flavonoid mempunyai efek antioksidan. Saat ini masih sangat terbatas uji klinis Phaleria macrocarpa (Scheff.) Boerl. Penelitian ini merupakan uji eksperimental sebelum dan sesudah perlakuan pada 30 sukarelawan sehat yang diinduksi dengan glukosa yang dilaksanakan pada bulan November 2018–Februari 2019 di Jakarta. Penelitian ini bertujuan menilai efek antioksidan ekstrak kering buah Phaleria macrocarpa (Scheff.) Boerl dalam beberapa kisaran dosis yang diberikan. Subjek penelitian berusia 30–55 tahun. Pengumpulan data meliputi pemeriksaan antropometri serta kadar malondialdehid sebelum dan sesudah pemberian ekstrak kering dosis 62,5 mg, 125 mg, dan 250 mg pada menit 150 setelah dilakukan induksi glukosa oral. Analisis data menggunakan uji t berpasangan dengan p<0,05. Penurunan kadar malondialdehid pada pemberian ekstrak Phaleria macrocarpa (Scheff.) Boerl dosis 62,5 mg, 125 mg, dan 250 mg sebesar 40,9%, 22,9%, dan 18,3% dibanding dengan kadar malondialdehid sebelum pemberian (1.608 nmol/mL). Analisis statistik menggunakan uji t berpasangan didapatkan p=0,000 untuk ketiga dosis dibanding dengan kadar awal. Ekstrak kering buah Phaleria macrocarpa (Scheff.) Boerl mempunyai efek antioksidan; efek antioksidan ekstrak tidak ber","PeriodicalId":31502,"journal":{"name":"Global Medical Health Communication","volume":"8 1","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41849429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eel Cookies Supplement and Incidence of Diarrhea in Children Aged 12–24 Months 补充鳗鱼饼干与12-24月龄儿童腹泻发生率的关系
Pub Date : 2020-04-30 DOI: 10.29313/GMHC.V8I1.3885
Nur Eva Aristina, D. Rachmadi, D. M. D. Herawati, H. Susiarno, D. A. Gurnida, D. Sunjaya
Diarrhea is one of the main causes of death in infants and toddlers in Indonesia. The Indonesian eel is a source of animal protein that contains high nutrients, including vitamin A and zinc, so it can be used to boost immunity. The objective of this study was to analyze the effect of eel cookies on the incidence of diarrhea in children. This was a double-blind randomized control trial (RCT) post-test study on 44 children aged 12–24 months at Garuda Public Health Center, Bandung city, who were selected using the simple random sampling method. The study was conducted for 2 months from January to February 2017. Data were analyzed using the Wilcoxon test. Results showed that there was an effect of eel cookies in reducing diarrhea incidence in toddlers (p<0.001), with no diarrhea condition seen among the toddlers among 18 children who had a history of diarrhea in the past and among 20 other children with no history of past diarrhea. In conclusion, eel cookies can reduce the incidence of diarrhea in children aged 12–24 months. Hence, it can be used as a functional food to improve child immunity as one of the efforts to prevent infectious diseases, especially diarrhea. SUPLEMENTASI COOKIES IKAN SIDAT TERHADAP KEJADIAN DIARE PADA BALITA USIA 12–24 BULAN Penyakit diare merupakan salah satu penyebab kematian utama pada bayi dan balita di Indonesia. Ikan sidat merupakan salah satu sumber protein hewani yang banyak mengandung vitamin A dan seng sehingga dapat meningkatkan kekebalan tubuh. Tujuan penelitian ini adalah menganalisis pengaruh pemberian cookies ikan sidat terhadap kejadian diare pada balita. Desain penelitian dengan randomized controll trial (RCT) posttest group design dengan double blind . Subjek penelitian adalah balita usia 12–24 bulan di Puskesmas Garuda Kota Bandung sebanyak 44 responden. Penelitian dilakukan selama 2 bulan mulai Januari–Februari 2017. Pengambilan sampel dilakukan secara acak sederhana. Analisis data menggunakan Uji Wilcoxon. Hasil penelitian menunjukkan pengaruh pemberian cookies ikan sidat terhadap penurunan kejadian diare pada balita (p<0,001), yaitu tidak ada perubahan kondisi balita dari tidak diare menjadi diare, dan terdapat 18 balita yang pernah memiliki riwayat penyakit diare mengalami perubahan setelah diberikan perlakuan sehingga tidak mengalami diare, sedangkan 20 orang di antara yang tidak memiliki riwayat penyakit diare setelah mendapatkan perlakuan tetap tidak mengalami diare. Simpulan, terdapat pengaruh pemberian cookies ikan sidat terhadap penurunan kejadian diare pada balita usia 12–24 bulan. Oleh karena itu, cookies ikan sidat dapat digunakan sebagai makanan fungsional untuk meningkatkan imunitas anak sebagai upaya pencegahan terhadap penyakit infeksi terutama diare.
腹泻是印度尼西亚婴幼儿死亡的主要原因之一。印尼鳗鱼是一种含有高营养物质的动物蛋白来源,包括维生素a和锌,所以它可以用来提高免疫力。本研究的目的是分析鳗鱼饼干对儿童腹泻发病率的影响。本研究采用简单随机抽样方法,对万隆市鹰路达公共卫生中心44名12-24月龄儿童进行双盲随机对照试验(RCT)后试验研究。该研究于2017年1月至2月进行了2个月。数据分析采用Wilcoxon检验。结果显示,鳗鱼饼干在降低幼儿腹泻发生率方面有效果(p<0.001), 18名有腹泻史的儿童和20名没有腹泻史的儿童中,幼儿没有出现腹泻情况。综上所述,鳗鱼饼干可以降低12-24月龄儿童腹泻的发生率。因此,它可以作为一种功能性食品来提高儿童的免疫力,作为预防传染病,特别是腹泻的努力之一。补充语曲奇IKAN SIDAT TERHADAP KEJADIAN DIARE PADA BALITA USIA 12-24 BULAN Penyakit DIARE merupakan salah satu penyebab kematian utama PADA bayi dan BALITA di IndonesiaIkan sidat merupakan salah satu sumu protein hewani yang banyak mengandung维生素A dan seng seingga dapat meningkatkan kekebalan tubuh。Tujuan penelitian ini adalah menganalis pengaruh pemberian cookies ikan sidat terhadap kejadian diare pada balita。登干随机对照试验(RCT)后验组设计登干双盲。主题penelitian adalah balita usia 12-24 bulan di Puskesmas Garuda Kota Bandung 44回应。Penelitian dilakukan selama 2 bulan mulai 2017年1 - 2月。彭甘比兰样品dilakukan secara akak sederhana。分析数据menggunakan Uji Wilcoxon。Hasil penelitian menunjukkan pengaruh pemberian cookies ikan sidat terhadap penurunan kejadian diare padalami diare (p< 0.001), yitu tidak ada perubahan kondisi balita dari tidak diare menjadi diare, dan terdapat 18 balita yang pernah memoriliki riwayat penyakit diare mengalami perubahan setelah diberikan perlakai sehinga tidak mengalami diare, sedangkan 20 orang di antara yang tidak memoriliki riwayat penyakit diare setelah mendapatkan perlakuan tetap tiak mengalami diare。Simpulan, terdapat pengaru, pemberian曲奇饼,例如,terapapat penurunan和kejadian的diapadbalita在12-24 bulan。Oleh karena itu, cookies ikan sidat digunakan sebagai makanan功能untuk脑膜炎疫苗anak sebagai upaya penegahan terhadap penyakit infeksi terutama diare。
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引用次数: 0
Effects of Pseudoephedrine Administration in Early Gestation on Female Mouse Heart 妊娠早期给药伪麻黄碱对雌性小鼠心脏的影响
Pub Date : 2019-12-31 DOI: 10.29313/GMHC.V7I3.5276
A. R. Furqaani, L. H. Siswanti, A. K. Sari
The pseudoephedrine in pregnant women associated with an increased risk of hypertension and increased heart rate. These conditions force the heart to work harder and cause changes in heart structure, such as left ventricular hypertrophy due to an increase in the number and size of muscle cells. This study aims to determine pseudoephedrine administration in early pregnancy on mice hearts histological features. This study was pure in vivo with a completely randomized design conducted at Medical Biology Laboratory, Faculty of Medicine, Universitas Islam Bandung, from January to August 2017. Subjects were 18 pregnant adult female mice randomly divided into four groups. One control group and three test groups were given oral pseudoephedrine every day at 0.312 mg/24 hours (P1); 0.624 mg/24 hours (P2); and 1.248 mg/24 hours (P3) for seven days starting from the age of pregnancy on day 1. On the 18 th day of gestational age, mice sacrificed, then the heart organ was processed into microscopic preparations and stained by Harris’ hematoxylin-eosin (HE) staining. Microscopic observations made using a microscope equipped with an optilab viewer with raster image 3. The results showed that the P3 group had a thicker left ventricular wall and significantly more heart muscle nuclei per mm 3 than the control group (p<0.05). The results show that the administration of high doses of pseudoephedrine in early pregnancy can affect the structure of the heart. PENGARUH PEMBERIAN PSEUDOEFEDRIN PADA MASA AWAL KEBUNTINGAN TERHADAP GAMBARAN HISTOLOGI JANTUNG MENCIT BETINA Aktivitas vasokontriksi pseudoefedrin pada ibu hamil diduga kuat berkaitan dengan peningkatan risiko hipertensi dan denyut jantung. Kondisi tersebut memaksa jantung bekerja lebih berat dan dapat menyebabkan perubahan struktur jantung seperti hipertrofi ventrikel kiri akibat peningkatan jumlah dan ukuran sel-sel otot. Tujuan penelitian ini mengetahui pengaruh pemberian pseudoefedrin pada masa awal kebuntingan terhadap gambaran histologi jantung mencit betina. Penelitian ini merupakan eksperimental laboratorium murni in vivo menggunakan rancangan acak lengkap yang dilaksanakan di Laboratorium Biologi Medik, Fakultas Kedokteran, Universitas Islam Bandung dari bulan Januari hingga Agustus 2017. Subjek penelitian adalah 18 mencit betina dewasa bunting yang dibagi secara acak menjadi empat kelompok. Satu kelompok kontrol dan tiga kelompok uji yang diberi pseudoefedrin oral setiap hari dengan dosis 0,312 mg/24 jam (P1); 0,624 mg/24 jam (P2); dan 1,248 mg/24 jam (P3) selama 7 hari dimulai dari umur kebuntingan hari ke-1. Pada hari ke-18 umur kebuntingan, mencit dikorbankan kemudian organ jantung diproses menjadi sediaan mikroskopis dan dilakukan pewarnaan Harris’ hematoxylin-eosin (HE). Pengamatan sediaan mikroskopik dilakukan dengan menggunakan mikroskop yang dilengkapi dengan optilab viewer dengan image raster 3 . Hasil penelitian menunjukkan kelompok P3 memiliki dinding ventrikel kiri yang lebih tebal dan jumla
孕妇服用伪麻黄碱会增加患高血压和心率的风险。这些情况迫使心脏更加努力地工作,并导致心脏结构的变化,例如由于肌肉细胞数量和大小的增加而导致的左心室肥大。本研究旨在确定孕早期服用伪麻黄碱对小鼠心脏组织学特征的影响。本研究为纯体内研究,采用完全随机设计,于2017年1月至8月在万隆伊斯兰大学医学院医学生物学实验室进行。受试者是18只怀孕的成年雌性小鼠,随机分为四组。一个对照组和三个试验组每天口服伪麻黄碱,剂量为0.312 mg/24小时(P1)0.624mg/24小时(P2);以及从第1天的怀孕年龄开始的7天的1248mg/24小时(P3)。在孕龄第18天,处死小鼠,然后将心脏器官加工成显微镜制剂,并通过Harris苏木精-伊红(HE)染色进行染色。使用配备有光栅图像3的光学实验室查看器的显微镜进行的显微镜观察。结果表明,P3组左心室壁较厚,每mm3心肌细胞核数明显多于对照组(p<0.05)。孕妇服用伪麻黄碱会增加患高血压和心率的风险。这种情况迫使心脏更加努力地工作,并可能导致心脏结构的变化,如由于肌肉细胞数量和大小的增加而导致的左心室肥大。本研究的目的是确定在综述的早期阶段给予伪麻黄碱对女性心脏组织学的影响。本研究是一个体内纯实验实验室,采用完全随机设计,于2017年1月至8月在万隆伊斯兰大学医学院生物医学实验室进行。研究对象是18名提及怀孕的成年妇女,她们被随机分为四组。一个对照组和三个口服伪麻黄碱试验组,每日剂量为0.312 mg/24小时(P1);0624 mg/24小时(P2);和1248mg/24小时(P3),从第1天龄开始持续7天。在青春期18周年纪念日,涂抹祭品,然后将心脏器官加工成显微镜制剂,并对Harris的苏木精-伊红(HE)进行染色。使用配备有具有图像光栅3的optilab查看器的显微镜进行显微镜准备状态观察。研究表明,与对照组相比,P3的左心室壁较厚,每毫米3心肌细胞核数较多(p<0.05)。结果表明,妊娠早期给予大剂量伪麻黄碱可能会影响心脏结构。
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引用次数: 0
Stunting Determinant on Toddler Age of 12–24 Months in Singaparna Public Health Center Tasikmalaya Regency 新加坡公共卫生中心12-24月龄儿童发育迟缓的决定因素
Pub Date : 2019-12-31 DOI: 10.29313/GMHC.V7I3.3673
Erwina Sumartini, D. A. Gurnida, E. Fadlyana, H. Susiarno, Kusnandi Rusmil, J. Effendi
Stunting is a physical growth failure condition signed by height based on age under −2SD. The research goal is knowing the dominant factor associated with stunting on toddler age of 12–24 months in the working area of Singaparna Public Health Center Tasikmalaya regency. The research applies to the cross-sectional design of gender, weight, exclusive breastfeeding history, completeness immunization, and clinically healthy variables, while case-control is for nutrition intake variable. The sample was a total sampling of 376 toddlers, then 30 for case and control group with the simple random method from December 2017 to February 2018. The instrument is a questionnaire, food frequency questionnaire (FFQ), and infantometer. Data analyzed in several ways; univariable, bivariable with chi-square, and multivariable with logistic regression. Research result shows stunting prevalence was 22.5%, next pertain factor of stunting are gender (POR=0.564, 95% CI=0.339–0.937, p value=0.011), exclusive breastfeeding giving history (POR=1.46, 95% CI=1.00–2.14, p value=0.046), and clinically health (POR=1.47, 95% CI=1.00–2.16, p value=0.044). Moreover, dominant factor were gender (OR=0.56, 95% CI=0.339–0.937, p value=0.027) and clinically health (OR=1.68, 95% CI=1.022–2.771, p value=0.041). Thus, gender and clinical health are stunting determinant factors. Children’s health should increase to create maximum growth. DETERMINAN STUNTING PADA ANAK USIA 12–24 BULAN DI PUSKESMAS SINGAPARNA KABUPATEN TASIKMALAYA Stunting merupakan kondisi kegagalan pertumbuhan fisik yang ditandai dengan tinggi badan menurut usia berada di bawah −2SD. Penelitian ini bertujuan mengetahui faktor determinan stunting pada anak usia 12–24 bulan di wilayah kerja Puskesmas Singaparna Kabupaten Tasikmalaya. Penelitian menggunakan desain cross-sectional untuk variabel jenis kelamin, berat badan lahir, riwayat ASI eksklusif, kelengkapan imunisasi, dan  sehat secara klinis, sedangkan desain case-control untuk variabel asupan nutrisi. Pengambilan sampel secara total sampling sejumlah 376 anak, selanjutnya diambil 30 anak untuk kelompok kasus dan kontrol dengan metode random sederhana periode Desember 2017 hingga Februari 2018. Instrumen menggunakan kuesioner, food frequency questionaire (FFQ), dan infantometer. Analisis data dilakukan secara univariabel, bivariabel dengan chi-square , dan multivariabel dengan regresi logistik. Hasil penelitian menunjukkan prevalensi stunting sebesar 22,6%, faktor yang berhubungan dengan stunting di antaranya jenis kelamin (POR=0,564; IK95%=0,339–0,937; p=0,011), riwayat pemberian ASI eksklusif (POR=1,46; IK95%=1,00–2,14, p=0,046), dan sehat secara klinis (POR=1,47; IK95%=1,00–2,16; p=0,044). Faktor dominan yang berhubungan dengan stunting adalah jenis kelamin (OR=0,56; IK95%=0,339–0,937; p=0,027) dan sehat secara klinis (OR=1,68; IK95%=1,022–2,771; p=0,041). Jenis kelamin dan sehat secara klinis merupakan faktor determinan stunting . Kesehatan anak perlu ditingkatkan un
发育迟缓是一种以年龄在- 2SD以下的身高为标志的身体生长衰竭状况。研究目的是了解新加坡公共卫生中心Tasikmalaya摄政区12-24月龄幼儿发育迟缓的主要因素。本研究采用性别、体重、纯母乳喂养史、完全免疫、临床健康变量的横断面设计,营养摄入变量采用病例对照。研究对象为2017年12月至2018年2月,采用简单随机方法抽取幼儿376人,对照组和病例各30人。该仪器是一份问卷,食物频率问卷(FFQ)和红外线计。用几种方法分析的数据;单变量,双变量卡方,多变量逻辑回归。研究结果显示,发育迟缓患病率为22.5%,其次为性别(POR=0.564, 95% CI=0.339 ~ 0.937, p值=0.011)、纯母乳喂养史(POR=1.46, 95% CI=1.00 ~ 2.14, p值=0.046)、临床健康状况(POR=1.47, 95% CI=1.00 ~ 2.16, p值=0.044)。显性因素为性别(OR=0.56, 95% CI=0.339 ~ 0.937, p值=0.027)和临床健康(OR=1.68, 95% CI=1.022 ~ 2.771, p值=0.041)。因此,性别和临床健康是发育迟缓的决定因素。儿童的健康应该增加,以创造最大的成长。决定性的发育迟缓padanakusia 12-24 BULAN DI PUSKESMAS SINGAPARNA KABUPATEN TASIKMALAYA发育迟缓merupakan kondisi kegagalan pertumbuhan finisik yang ditandai dengan tinggi badan menurut USIA berada DI bawah - 2SD。Penelitian ini bertujuan mengetahui决定发育迟缓的因素在12-24岁时发生了变化,在12-24岁时发生了变化。Penelitian menggunakan设计了横截面untuk变量jenis kelamin, berat badan lahir, riwayat ASI eksklusif, kelengkapan imunisasi, dan sehat secara klinis, sedangkan设计了病例对照untuk变量asupan nutrisi。彭甘比兰样本总采样次数为376次,selanjutnya diambil 30次,kelompok kasus dan control dengan方法随机采样时间为2017年12月至2018年2月。实验仪器:蒙古纳坎测量仪、食物频率问卷(FFQ)、胰岛素计。分析数据采用单变量、双变量登根卡方、多变量登根回归logistic分析。Hasil penelitian menunjukkan prevalensis发育迟缓sebesar 22,6%, factor for yang berhubungan dengan发育迟缓di antaranya jenis kelamin (POR= 0.564;IK95% = 0339 - 0937;p= 0.011), riwayat pemberian ASI eksklusif (POR=1,46;IK95%=1,00 - 2,14, p=0,046), dan sehat secara klinis (POR=1,47;IK95% = 1 00-2 16;p = 0044)。主要因子:杨伯虎,邓,邓,发育迟缓adalah jenis kelamin (OR=0,56;IK95% = 0339 - 0937;p= 0.027) dan sehat secara klinis (OR=1,68;IK95% = 1022 - 2771;p = 0041)。詹尼斯·克拉明(Jenis kelamin)是决定性发育迟缓的一个因素。Kesehatan anak perlu ditingkatkan untuk menciptakan pertumbuhan anak yang maksimal。
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引用次数: 2
Phylogenetic Analysis of Culex tritaeniorhynchus and Culex vishnui Vector of Japanese Encephalitis Virus 三带喙库蚊与日本脑炎病毒威氏库蚊载体的系统发育分析
Pub Date : 2019-12-31 DOI: 10.29313/GMHC.V7I3.4051
Raden Roro Upiek Ngesti Wibawaning Astuti, R. W. Nurcahyo, R. Soesilohadi, S. Hadisusanto, Budi Mulyaningsih
Culex tritaeniorhynchus and Culex vishnui are medically essential mosquitoes that transmit the Japanese encephalitis (JE) virus. There is less information about the recording data and research due to genetic character differences among them. The objective of this study was to examine the genetic variation of Cx. tritaeniorhynchus and Cx. vishnui in 3 sites of Central Java using polymerase chain reaction randomly amplified polymorphic DNA (PCR-RAPD). The study was done in January to November 2017 in Pekalongan city, Pekalongan regency, and Semarang regency. Adult female mosquitoes collected by human bite method. DNA of ten Cx. tritaeniorhynchus samples and fifteen samples of Cx. vishnui purified using DNA extraction kit. Furthermore, PCR amplification was conducted with 5 RAPD primers (OPA 11, 12, 15, 16, and 20) and would run into 2% gel electrophoresis for 45 minutes. Cluster analysis was using MVSPTM software (version 3.1). The results showed 213 genetic characters of Cx. vishnui , while 142 characters shown by Cx. tritaeniorhynchus . The dendrograms showed three distinct groups of Cx. vishnui from 2 sites of Pekalongan and one site of Semarang, while Cx. tritaeniorhynchus showed two distinct groups, which were 1 group from Pekalongan and 1 group from Semarang. Low genetic similarity (<10%) shown Cx. vishnui from Pekalongan city and Pekalongan district, and there was no genetic similarity in Cx. tritaeniorhynchus from Pekalongan and Semarang. It concluded that the polymorphism of Cx. tritaeniorhynchus and Cx. vishnui reached 100%. ANALISIS FILOGENETIK CULEX TRITAENIORHYNCHUS DAN CULEX VISHNUI VEKTOR VIRUS JAPANESE ENCEPHALITIS Nyamuk Culex tritaeniorhynchus dan Culex vishnui memiliki peran penting di bidang medis terutama dalam penularan virus Japanese  encephalitis (JE). Sampai saat ini data dan riset tentang karakter genetik vektor JE masih sangat terbatas. Penelitian ini bertujuan menjelaskan variasi genetik Cx. tritaeniorhynchus dan Cx. vishnui di 3 lokasi di Jawa Tengah berdasar polymerase chain reaction randomly amplified polymorphic DNA (PCR-RAPD). Studi ini dilakukan dari bulan Januari sampai November 2017 di Kota Pekalongan, Kabupaten Pekalongan, dan Kabupaten Semarang. Metode human bite digunakan untuk koleksi nyamuk. Ekstraksi DNA nyamuk dilakukan pada 10 ekor Cx. tritaeniorhynchus dan 15 ekor Cx. vishnui menggunakan kit ekstraksi DNA. Selanjutnya, diamplifikasi dengan 5 macam primer RAPD (OPA 11, 12, 15, 16, dan 20), serta dielektroforesis pada 2% agar selama 45 menit. Analisis klaster dilakukan menggunakan program MVSPTM (versi 3.1). Ditemukan 213 dan 142 karakter genetik masing-masing pada Cx. vishnui dan Cx. tritaeniorhynchus . Analisis dendogram menunjukkan 3 grup yang berbeda untuk Cx. vishnui , sedangkan untuk Cx. tritaeniorhynchus terdapat 2 grup yang berbeda, yaitu 1 grup dari Pekalongan dan 1 grup dari Semarang. Similaritas genetik yang rendah (<10%) ditunjukkan Cx. vishnui dari Kota Pekalongan dan Kabupaten Pekalongan, bah
三带喙库蚊和vishnui库蚊是传播日本脑炎病毒的医学上必不可少的蚊子。由于它们之间的遗传特征差异,有关记录数据和研究的信息较少。本研究采用聚合酶链式反应随机扩增多态性DNA(PCR-RAPD)方法,检测爪哇中部3个地区三带喙钩虫(Cx.tritaeniorynchus)和毗湿奴虫(Cx.vishnui)的遗传变异。该研究于2017年1月至11月在佩卡隆安市、佩卡隆甘县和三宝垄县进行。采用人叮咬法采集成年雌蚊。用DNA提取试剂盒纯化了10个三带喙钩虫样品和15个毗湿奴虫样品的DNA。此外,用5个RAPD引物(OPA 11、12、15、16和20)进行PCR扩增,并进行2%凝胶电泳45分钟。利用MVSPTM软件(3.1版)进行聚类分析,结果表明:毗湿奴蛛有213个遗传性状,三带喙喙蛛有142个遗传性状。从两个Pekalongan和一个Semarang的位置,树状图显示了三个不同的Cx.vishnui组,而Cx.tritaeniorhynchus显示了两个不同的组,分别是Pekalongan1组和Semarang 1组。Pekalongan市和Pekalonggan区的Cx.vishnui基因相似性较低(<10%),而Pekalong安和三宝垄的Cx.tritaeniorhynchus基因不相似。结果表明,三带喙钩虫和vishnui的多态性达到100%。三带喙库蚊和库蚊-毗湿奴伊病媒日本脑炎到目前为止,关于乙脑载体遗传特性的数据和研究仍然非常有限。本研究的目的是利用聚合酶链反应随机扩增多态性DNA(PCR-RAPD),解释三带钩藤和vishnui在中段3个位置的遗传变异。本研究于2017年1月至11月在监狱城、监狱内阁和语义内阁进行。用于蚊子采集的人类叮咬方法。使用DNA提取试剂盒对10Cx.tritaeniorynchus和15Cx.vishnui尾巴进行猴子DNA提取。然后,用5个RAPD引物(OPA 11、12、15、16和20)扩增,在2%的条件下介电45分钟。使用MVSPTM程序(3.1版)进行聚类分析。在Cx.vishnui和Cx.tritaeniorhynchus上分别发现213和142个遗传特征。树状图分析显示,Cx.vishnui有3个不同的群,而Cx.tritaeniorhynchus有2个不同的组,即1组Pekalongan和1组Semarang。独立之城的Cx.vishnui和独立能力表现出较低的遗传相似性(<10%),甚至与三宝垄的Cx.tritaeniorhynchus没有遗传相似性。结果表明,三带喙和毗湿奴的多态性达到100%。
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引用次数: 0
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Global Medical Health Communication
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