Nur Azizah AS, Lysa Veterini, Hafid Algristian, H. M. Salim
Introduction: Chronic stress exposure plays a role as a risk factor for depression. In chronic stress, there is prunning of nerve cell dendrites so that depression becomes irreversible. Depression is caused by low serotonin (5-HT2) neurotransmitters in the postsynaptic cleft. Recent findings in experimental animals indicate that serotonergic preparations are required to increase serotonin levels in the synapse opening, thereby triggering the formation of new dendrites to make depression reversible. The different results when these preparations create resistance in cases of chronic depression and actually increase the risk of uncomfortable and even fatal side effects with long-term use.Methods: This Systematic Literature Review uses the PubMed and Google Scholar databases for the period 2015-2020. A total of 322 articles at the beginning of identification and those that met the inclusion criteria in this study were six articles.Results: The results of data extraction showed that the depression condition caused by various stressors resulted in BDNF levels in the hippocampus decreased significantly by p≤0.005.Conclusion: Based on the literature study, it was concluded that in depressive conditions, BDNF levels in the brain decreased.
{"title":"Expression of Brain-Derived Neurotrophic Factor in the Brain of Depressed Mice: Systematic Literature Review","authors":"Nur Azizah AS, Lysa Veterini, Hafid Algristian, H. M. Salim","doi":"10.30651/JQM.V5I2.6354","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.6354","url":null,"abstract":"Introduction: Chronic stress exposure plays a role as a risk factor for depression. In chronic stress, there is prunning of nerve cell dendrites so that depression becomes irreversible. Depression is caused by low serotonin (5-HT2) neurotransmitters in the postsynaptic cleft. Recent findings in experimental animals indicate that serotonergic preparations are required to increase serotonin levels in the synapse opening, thereby triggering the formation of new dendrites to make depression reversible. The different results when these preparations create resistance in cases of chronic depression and actually increase the risk of uncomfortable and even fatal side effects with long-term use.Methods: This Systematic Literature Review uses the PubMed and Google Scholar databases for the period 2015-2020. A total of 322 articles at the beginning of identification and those that met the inclusion criteria in this study were six articles.Results: The results of data extraction showed that the depression condition caused by various stressors resulted in BDNF levels in the hippocampus decreased significantly by p≤0.005.Conclusion: Based on the literature study, it was concluded that in depressive conditions, BDNF levels in the brain decreased.","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78613967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dian Dwi Sari, I. Irwanto, A. Suryawan, Mira Irmawati, B. Utomo
AbstractBackground: Developmental problems concerned by parents are a further diagnostic step for children with ASD. Research is needed to find a picture of the child's behavior complained of by parents. Investigations about first concerns among parents of children with ASD and comparisons of the same with children diagnosed with other developmental disorders are rare.Objective: to examine the type and age of parents ‘concern in children with ASD and other developmental disorders.Method:A cross-sectional study was conducted in Child Developmental Centre in Surabaya Indonesia from August 1 to December 30, 2019. T-test and chi-square tests were used to analyze differences in subject variables and types of concern.Result: Most parents of both children diagnosed with ASD and non-ASD indicated first concern were in communication, social skill, and behavior problem. The average age of parents’ first concern of ASD children is 30,14 months. Significant differences were found between ASD and non-ASD groups in communications, behavior, and sensory problem concerns. Conclusion: There is no specific difference between parental concerns of children with ASD and non-ASD children. The average age of first concern was significantly younger for children with an ASD diagnosis than other developmental disorders.Keywords :parent concern, autism, communication.Correspondence :dian_dwisary@yahoo,com
摘要背景:家长关注的发育问题是自闭症儿童诊断的进一步步骤。需要进行研究，找出被父母抱怨的孩子行为的全貌。关于自闭症儿童父母首要关注的问题的调查，以及与诊断为其他发育障碍的儿童的比较，都很少见。目的:了解ASD及其他发育障碍患儿家长关注的类型和年龄。方法:于2019年8月1日至12月30日在印度尼西亚泗水儿童发展中心进行横断面研究。采用t检验和卡方检验分析被试变量和关注类型的差异。结果:诊断为ASD和非ASD的儿童的大多数家长首先关注的是沟通、社交技能和行为问题。父母首次关注ASD儿童的平均年龄为30,14个月。ASD组和非ASD组在沟通、行为和感觉问题方面存在显著差异。结论:ASD患儿与非ASD患儿的父母关注点无明显差异。被诊断为自闭症谱系障碍的儿童首次关注的平均年龄明显低于其他发育障碍的儿童。关键词:父母关怀，自闭症，沟通。函授:dian_dwisary@yahoo, com
{"title":"Parental first concern according to age and type in children with ASD","authors":"Dian Dwi Sari, I. Irwanto, A. Suryawan, Mira Irmawati, B. Utomo","doi":"10.30651/JQM.V5I2.5738","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.5738","url":null,"abstract":"AbstractBackground: Developmental problems concerned by parents are a further diagnostic step for children with ASD. Research is needed to find a picture of the child's behavior complained of by parents. Investigations about first concerns among parents of children with ASD and comparisons of the same with children diagnosed with other developmental disorders are rare.Objective: to examine the type and age of parents ‘concern in children with ASD and other developmental disorders.Method:A cross-sectional study was conducted in Child Developmental Centre in Surabaya Indonesia from August 1 to December 30, 2019. T-test and chi-square tests were used to analyze differences in subject variables and types of concern.Result: Most parents of both children diagnosed with ASD and non-ASD indicated first concern were in communication, social skill, and behavior problem. The average age of parents’ first concern of ASD children is 30,14 months. Significant differences were found between ASD and non-ASD groups in communications, behavior, and sensory problem concerns. Conclusion: There is no specific difference between parental concerns of children with ASD and non-ASD children. The average age of first concern was significantly younger for children with an ASD diagnosis than other developmental disorders.Keywords :parent concern, autism, communication.Correspondence :dian_dwisary@yahoo,com","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86925987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lutfi Nur Farid, Hardiono Hardiono, Pesta Parulian Maurid Edwar
Abstract Identification of patients’ fluid status in the emergency room should be made before giving fluid therapy. This study aimed to determine the effect of positive end-expiratory pressure on change in end-tidal carbon dioxide during passive leg raising maneuver to predict fluid responsiveness. Thirty subjects aged 18-65 years in the resuscitation room, all on the ventilator, were divided into three groups according to their positive end-expiratory pressure value: low (0-5 cmH2O), moderate (6-10 cmH2O), and high (>10 cmH2O). Every subject underwent passive leg raising to simulate fluid administration. Values of blood pressure, heart rate, cardiac output, and end-tidal carbon dioxide were recorded before and after the maneuver. Analysis of the three groups found a significant correlation between change in end-tidal carbon dioxide with a cut-off value of 5% and 1 mmHg with fluid responsiveness of subjects in the low (p = 0.028) and moderate (p = 0.013) but not in the high positive end-expiratory pressure group (p = 0.333). In conclusion, change in end-tidal carbon dioxide in mechanically ventilated patients undergoing passive leg raising maneuvers can be used as a predictor of fluid responsiveness, but this method cannot be used on patients with high positive end-expiratory pressure (> 10 cmH2O) Keywords : change in end tidal carbon dioxide, fluid responsiveness, positive end-expiratory pressure, passive leg raising, cardiac output surrogateCorrespondence : lutfithe13th@gmail.com
{"title":"Effect of positive end-expiratory pressure value on change in end-tidal carbon dioxide as a predictor of fluid responsiveness in Patients Undergoing Passive Leg Raising Maneuver","authors":"Lutfi Nur Farid, Hardiono Hardiono, Pesta Parulian Maurid Edwar","doi":"10.30651/JQM.V5I2.5458","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.5458","url":null,"abstract":"Abstract Identification of patients’ fluid status in the emergency room should be made before giving fluid therapy. This study aimed to determine the effect of positive end-expiratory pressure on change in end-tidal carbon dioxide during passive leg raising maneuver to predict fluid responsiveness. Thirty subjects aged 18-65 years in the resuscitation room, all on the ventilator, were divided into three groups according to their positive end-expiratory pressure value: low (0-5 cmH2O), moderate (6-10 cmH2O), and high (>10 cmH2O). Every subject underwent passive leg raising to simulate fluid administration. Values of blood pressure, heart rate, cardiac output, and end-tidal carbon dioxide were recorded before and after the maneuver. Analysis of the three groups found a significant correlation between change in end-tidal carbon dioxide with a cut-off value of 5% and 1 mmHg with fluid responsiveness of subjects in the low (p = 0.028) and moderate (p = 0.013) but not in the high positive end-expiratory pressure group (p = 0.333). In conclusion, change in end-tidal carbon dioxide in mechanically ventilated patients undergoing passive leg raising maneuvers can be used as a predictor of fluid responsiveness, but this method cannot be used on patients with high positive end-expiratory pressure (> 10 cmH2O) Keywords : change in end tidal carbon dioxide, fluid responsiveness, positive end-expiratory pressure, passive leg raising, cardiac output surrogateCorrespondence : lutfithe13th@gmail.com","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73375686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACTCovid-19 (coronavirus disease 2019) had spread to the whole world. This kind of virus attacks the human respiratory system, and it caused death. In other words, there were many symptoms of Covid-19, which attacks the respiratory system. One of the symptoms was anosmia or smell disorder. This research might provide information about the anosmia in Covid-19 patients. This study aimed to investigate and present a series about anosmia and Covid-19 in Yogyakarta on June 2020. Three cases from three patients of RT-PCR-confirmed SARS-CoV-2-infected patients diagnosed with smell disorder were presented, starting from the symptom until the patients were getting treatments. This research also explained anosmia as one of the symptoms of Covid-19. Anosmia or losing olfactory function or smell disorder which could distract people’s healthy. Then, in this situation, it could be one of the symptoms of Covid-19. Keywords : anosmia, smell disorder, covid-19Corresponding Author : rizkafakhriani@gmail.com
{"title":"Anosmia and covid-19 in Yogyakarta, Indonesia: a case series","authors":"Rizka Fakhriani, Asti Widuri","doi":"10.30651/JQM.V5I2.7502","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.7502","url":null,"abstract":"ABSTRACTCovid-19 (coronavirus disease 2019) had spread to the whole world. This kind of virus attacks the human respiratory system, and it caused death. In other words, there were many symptoms of Covid-19, which attacks the respiratory system. One of the symptoms was anosmia or smell disorder. This research might provide information about the anosmia in Covid-19 patients. This study aimed to investigate and present a series about anosmia and Covid-19 in Yogyakarta on June 2020. Three cases from three patients of RT-PCR-confirmed SARS-CoV-2-infected patients diagnosed with smell disorder were presented, starting from the symptom until the patients were getting treatments. This research also explained anosmia as one of the symptoms of Covid-19. Anosmia or losing olfactory function or smell disorder which could distract people’s healthy. Then, in this situation, it could be one of the symptoms of Covid-19. Keywords : anosmia, smell disorder, covid-19Corresponding Author : rizkafakhriani@gmail.com","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88284006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahendra Dwi Aditya Lopulalan, P. Airlangga, Arie Utariani
Abstract Muscle wasting in critical illness is seen from inadequate nutrition intake and stress catabolism. Modified Nutrition Risk in the Critically Ill (NUTRIC) Score is a screening tool that measures starvation, inflammation, disease severity, and organ dysfunction. Relationship between muscle strength and muscle thickness causes the evaluation of muscle thickness is quite relevant. This study aimed to analyze the relationship between modified NUTRIC score and nutrition with muscle wasting in critically ill patients. The study was conducted on 30 patients in the ICU Dr Soetomo Hospital Surabaya. Nutritional intake and thickness of the quadriceps femoris muscle were monitored for one week. There was a relationship between mNUTRIC score with quadriceps femoris muscle thickness on days 3rd, 5th, and 7th. In the comparison between the low risk group and the high-risk group, it was found that there was a significant difference in the change in the percentage of muscle thickness difference on the 3rd, 5th and 7th day observation. There is a relationship between protein debt with quadriceps femoris muscle thickness (p = 0.008) with a positive correlation with moderate correlation strength (r = 0.477) on day 7. In conclusion, the modified NUTRIC Score had a moderate relationship with quadriceps femoris muscle thickness in critical patients from day 3rd until day 7th. The calorie intake not had a relationship with quadriceps femoris muscle thickness. Protein intake had a moderate relationship with quadriceps femoris muscle thickness only on day 7th measurement in critical patients. Keywords : Modified NUTRIC Score, Nutrition, Quadriceps Femoris muscleCorrespondence : mdr.lopulalan@gmail.com
{"title":"Relationship between modified Nutrition Risk in the Critically Ill (mNUTRIC) Score and nutrition intake with quadriceps femoris muscle thickness in critically ill patients","authors":"Mahendra Dwi Aditya Lopulalan, P. Airlangga, Arie Utariani","doi":"10.30651/JQM.V5I2.6257","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.6257","url":null,"abstract":"Abstract Muscle wasting in critical illness is seen from inadequate nutrition intake and stress catabolism. Modified Nutrition Risk in the Critically Ill (NUTRIC) Score is a screening tool that measures starvation, inflammation, disease severity, and organ dysfunction. Relationship between muscle strength and muscle thickness causes the evaluation of muscle thickness is quite relevant. This study aimed to analyze the relationship between modified NUTRIC score and nutrition with muscle wasting in critically ill patients. The study was conducted on 30 patients in the ICU Dr Soetomo Hospital Surabaya. Nutritional intake and thickness of the quadriceps femoris muscle were monitored for one week. There was a relationship between mNUTRIC score with quadriceps femoris muscle thickness on days 3rd, 5th, and 7th. In the comparison between the low risk group and the high-risk group, it was found that there was a significant difference in the change in the percentage of muscle thickness difference on the 3rd, 5th and 7th day observation. There is a relationship between protein debt with quadriceps femoris muscle thickness (p = 0.008) with a positive correlation with moderate correlation strength (r = 0.477) on day 7. In conclusion, the modified NUTRIC Score had a moderate relationship with quadriceps femoris muscle thickness in critical patients from day 3rd until day 7th. The calorie intake not had a relationship with quadriceps femoris muscle thickness. Protein intake had a moderate relationship with quadriceps femoris muscle thickness only on day 7th measurement in critical patients. Keywords : Modified NUTRIC Score, Nutrition, Quadriceps Femoris muscleCorrespondence : mdr.lopulalan@gmail.com","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90515726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Syafarinah Nur Hidayah Akil, H. Arwati, Puspa Wardhani, P. A. Wiratama
AbstractMalaria is a parasitic infectious disease caused by Plasmodium, which remains a world health problem with an estimated 219 million cases worldwide. In severe malaria infection, several organs of the body can be affected, including the kidneys. One of the pathophysiology associated with the worsening of this disease is oxidative stress. The use of antioxidants is expected to prevent this, and one product that has a high antioxidant content is virgin coconut oil (VCO). This study aimed to analyze the effect of VCO on the kidney in Plasmodium berghei ANKA-infected mice. This study was an in vivo laboratory experimental study with a randomized post-test only control group design using 35 BALB/c mice infected with P. berghei ANKA, weighing 20-30 grams. VCO with the Javara® brand is used with doses of 1, 5, and 10 ml/kg body weight (kgBW)/ day. The parameter assessed were levels of BUN, creatinine, and renal histopathological changes. The administration of VCO on the treated group shows minimal tubular necrosis and glomerulonephritis compared to the negative control group. The BUN and creatinine levels in the treated group were also lower than the negative control group. The results showed that VCO has a nephroprotective effect against P. berghei ANKA infection in mice.Keywords: malaria, kidney, virgin coconut oil
{"title":"Nephroprotective effect of virgin coconut oil in Plasmodium berghei ANKA infected Balb/c mice","authors":"Syafarinah Nur Hidayah Akil, H. Arwati, Puspa Wardhani, P. A. Wiratama","doi":"10.30651/JQM.V5I2.5791","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.5791","url":null,"abstract":"AbstractMalaria is a parasitic infectious disease caused by Plasmodium, which remains a world health problem with an estimated 219 million cases worldwide. In severe malaria infection, several organs of the body can be affected, including the kidneys. One of the pathophysiology associated with the worsening of this disease is oxidative stress. The use of antioxidants is expected to prevent this, and one product that has a high antioxidant content is virgin coconut oil (VCO). This study aimed to analyze the effect of VCO on the kidney in Plasmodium berghei ANKA-infected mice. This study was an in vivo laboratory experimental study with a randomized post-test only control group design using 35 BALB/c mice infected with P. berghei ANKA, weighing 20-30 grams. VCO with the Javara® brand is used with doses of 1, 5, and 10 ml/kg body weight (kgBW)/ day. The parameter assessed were levels of BUN, creatinine, and renal histopathological changes. The administration of VCO on the treated group shows minimal tubular necrosis and glomerulonephritis compared to the negative control group. The BUN and creatinine levels in the treated group were also lower than the negative control group. The results showed that VCO has a nephroprotective effect against P. berghei ANKA infection in mice.Keywords: malaria, kidney, virgin coconut oil","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74391679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Purwowiyoto, Reynaldo Halomoan Siregar, S. P. Surya
Patients with total atrioventricular block or sinus node dysfunction will need pacemaker implantation to improve the physiologic function of the heart. It is known that chronic pacing such as right ventricular pacing could deteriorate the cardiac function (decreased left ventricular ejection fraction) due to dyssynchrony. This condition is knows as pacing-induced cardiomyopathy (PICM). The incidence of PICM could reach 19.5% during 3 years follow-up. The right ventricle is one of the locations for implantation. Chronic right ventricular pacing may cause interventricular dyssynchrony and disrupt the contraction mechanism in the heart. These will lead to cardiac remodeling and eventually impair the left ventricular function. Therapy is needed in patients with PICM to improve the symptoms and maintain the cardiac function. This article will further highlight the definition, mechanism, risk factor, treatment and preventive strategy for patients with PICM.
{"title":"Understanding Pacing-Induced Cardiomyopathy: a mini review","authors":"S. Purwowiyoto, Reynaldo Halomoan Siregar, S. P. Surya","doi":"10.30651/JQM.V5I2.6036","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.6036","url":null,"abstract":"Patients with total atrioventricular block or sinus node dysfunction will need pacemaker implantation to improve the physiologic function of the heart. It is known that chronic pacing such as right ventricular pacing could deteriorate the cardiac function (decreased left ventricular ejection fraction) due to dyssynchrony. This condition is knows as pacing-induced cardiomyopathy (PICM). The incidence of PICM could reach 19.5% during 3 years follow-up. The right ventricle is one of the locations for implantation. Chronic right ventricular pacing may cause interventricular dyssynchrony and disrupt the contraction mechanism in the heart. These will lead to cardiac remodeling and eventually impair the left ventricular function. Therapy is needed in patients with PICM to improve the symptoms and maintain the cardiac function. This article will further highlight the definition, mechanism, risk factor, treatment and preventive strategy for patients with PICM.","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85439141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Worm infection is one of the health problems in all tropical countries, including Indonesia. The most frequent helminthiasis is the infection caused by the Soil-Transmitted Helminth. Primary school-age children are an age group that is susceptible to helminthiasis. Worm infections can cause a serious impact if left untreated with no clean and healthy lifestyle. This study was conducted to determine the prevalence and risk factors of STH in children of Manusak Village, East Kupang Subdistrict, Kupang District, East Nusa Tenggara Province, followed by the characterization of subjects. The analytic observational design with the cross-sectional study was applied to this research. Research subjects were 130 children aged 6-12 years old. The infection was diagnosed microscopically by the Katokatz method. Ascaris lumbricoides were the only species found infecting a total of 50 children (38.4%.). The distribution of ascariasis was higher in girls (30 or 23.08%) than in boys (20 or 15.38%), in children whose parents have no formal education (41 or 31.54%), and who their professions are a farmer. Poor hygiene and sanitation such as no washing hands with soap (27 or 20.77%) as well as the habit of not wearing footwear (47 or 36.2%) and bowel habit on the open areas (35 or 26.92%) are the risks factors causing the high incidence of A. lumbricoides in the studied area. Enlightenment to the parents regarding good personal and environmental hygiene and sanitation along with chemotherapy from the government and related agencies is needed to achieve a durable reduction of the burden of ascariasis and other STH infection. Keywords : Soil Transmitted Helminth, Ascaris lumbricoides, children, Kupang DistrictCorrespondence : heny-a@fk.unair.ac.id
{"title":"Prevalence and risk factors of Ascaris lumbricoides infection in children of Manusak Village, Kupang District, East Nusa Tenggara Province, Indonesia","authors":"Meliance Bria, H. Arwati, I. Tantular","doi":"10.30651/JQM.V5I2.5191","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.5191","url":null,"abstract":"ABSTRACT Worm infection is one of the health problems in all tropical countries, including Indonesia. The most frequent helminthiasis is the infection caused by the Soil-Transmitted Helminth. Primary school-age children are an age group that is susceptible to helminthiasis. Worm infections can cause a serious impact if left untreated with no clean and healthy lifestyle. This study was conducted to determine the prevalence and risk factors of STH in children of Manusak Village, East Kupang Subdistrict, Kupang District, East Nusa Tenggara Province, followed by the characterization of subjects. The analytic observational design with the cross-sectional study was applied to this research. Research subjects were 130 children aged 6-12 years old. The infection was diagnosed microscopically by the Katokatz method. Ascaris lumbricoides were the only species found infecting a total of 50 children (38.4%.). The distribution of ascariasis was higher in girls (30 or 23.08%) than in boys (20 or 15.38%), in children whose parents have no formal education (41 or 31.54%), and who their professions are a farmer. Poor hygiene and sanitation such as no washing hands with soap (27 or 20.77%) as well as the habit of not wearing footwear (47 or 36.2%) and bowel habit on the open areas (35 or 26.92%) are the risks factors causing the high incidence of A. lumbricoides in the studied area. Enlightenment to the parents regarding good personal and environmental hygiene and sanitation along with chemotherapy from the government and related agencies is needed to achieve a durable reduction of the burden of ascariasis and other STH infection. Keywords : Soil Transmitted Helminth, Ascaris lumbricoides, children, Kupang DistrictCorrespondence : heny-a@fk.unair.ac.id","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90728906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Extranodal Non-Hodgkin Lymphoma (NHL) remains an odd issue and something to discuss. Clinical evidence and guidelines on the treatment have not yet been broadly published and accessible. Here, we present a case of a thirty-eight years old woman complaining of mass on both lower lids of the eyes. The CT Scan examination showed enhancing solid masses on right-sided and left-sided palpebra inferior that press bulb oculi, suspected as bilateral malignant masses of bilateral palpebra inferior. Laboratory data revealed the surge of liver function marker. The patient was eventually diagnosed with Non-Hodgkin Lymphoma (NHL) of palpebra inferior B cell type high-grade stadium II E. Although there are still ongoing research and development of definitive treatments, R-CHOP a regiment given to this patient has shown complete favorable result with dosage adjustment due to the surge of basal liver function. The regiment was considered safe since no adverse effects reportedKeywords: extranodal, lymphoma non-hodgkin, palpebra, liver function
{"title":"Palpebral Non-Hodgkin Lymphoma with Non-specific Reactive Hepatitis","authors":"P. Z. Romadhon, B. A. Mahdi, U. Y. Bintoro","doi":"10.30651/JQM.V5I2.7550","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.7550","url":null,"abstract":"ABSTRACT Extranodal Non-Hodgkin Lymphoma (NHL) remains an odd issue and something to discuss. Clinical evidence and guidelines on the treatment have not yet been broadly published and accessible. Here, we present a case of a thirty-eight years old woman complaining of mass on both lower lids of the eyes. The CT Scan examination showed enhancing solid masses on right-sided and left-sided palpebra inferior that press bulb oculi, suspected as bilateral malignant masses of bilateral palpebra inferior. Laboratory data revealed the surge of liver function marker. The patient was eventually diagnosed with Non-Hodgkin Lymphoma (NHL) of palpebra inferior B cell type high-grade stadium II E. Although there are still ongoing research and development of definitive treatments, R-CHOP a regiment given to this patient has shown complete favorable result with dosage adjustment due to the surge of basal liver function. The regiment was considered safe since no adverse effects reportedKeywords: extranodal, lymphoma non-hodgkin, palpebra, liver function","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75917101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cornellius Hendra Purnama Aria Sumantrie, B. Semedi, B. Purwanto
ABSTRACT Catheter Vein Pressure in ward-cared patients is rarely measured and considered invalid. The two catheter vein pressure postulates contradict, making confusion among health workers. Dr Russo said the distal-medial-proximal Catheter Vein Pressure has no difference but were denied by Susan S. Scott. Proof of postulate is needed as a solution to inward care. Therefore, this study aimed to compare the central vein pressure between distal, medial, and proximal lumens with the water manometer method. Forty-nine samples retrospective study were taken from the distal - medial - proximal Catheter Vein Pressure of the "zero" until fifth days. The differences are analyzed with Statistical Paired t Test with p-Value < 0.05 from SPSS ver. 26 to prove the right postulate. 49 samples were concluded to represent of population. Catheter Vein Pressure from day "zero" becomes zero difference, the fifth day 91.8% are no difference while the rest have difference of 0.2 - 1.0 cm H2O and the conclusion are no significant difference with 95% CI. The correlation scale of 0.998 and 0.999 proves that the three lumens tend to produce no differences. In conclusion, the distal - medial - proximal Catheter Vein Pressure values in this study have no significant differences and consistent from "zero" until fifth days. This is formulated as P distal = P medial = P proximal (cm H2O). Keywords : Central Vein Pressure, Pressure, distal - medial - proximal, no differences, ward patient. Correspondence : sumantrie_medicalgp@yahoo.com
在病房监护的患者中，很少测量导管静脉压力，并认为其无效。两种导管静脉压力假设相互矛盾，使卫生工作者感到困惑。Russo医生说远端-中端-近端导管静脉压力没有区别，但被Susan S. Scott否认。为了解决内心的忧虑，需要假设的证明。因此，本研究旨在用水压计法比较远端、中端和近端管腔之间的中心静脉压力。回顾性研究49个样本从远端-中端-近端取导管静脉压为“零”直至第五天。采用SPSS统计软件的配对t检验，p值< 0.05。证明正确的假设。49个样本代表总体。导管静脉压从“0”天开始变为零差，第5天91.8%无差异，其余相差0.2 ~ 1.0 cm H2O，结论差异无统计学意义，95% CI。0.998和0.999的相关尺度证明三个流明趋向于不产生差异。综上所述，本研究中远端、内端和近端导管静脉压力值无显著差异，从“零”一直持续到第5天。公式为P远端= P内侧= P近端(cm H2O)。关键词:中心静脉压力，压力，远端-中端-近端，无差异，病房病人。通信:sumantrie_medicalgp@yahoo.com
{"title":"Comparison of central vein pressure between distal, medial, and proximal lumens with water manometer method","authors":"Cornellius Hendra Purnama Aria Sumantrie, B. Semedi, B. Purwanto","doi":"10.30651/JQM.V5I2.5356","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.5356","url":null,"abstract":"ABSTRACT Catheter Vein Pressure in ward-cared patients is rarely measured and considered invalid. The two catheter vein pressure postulates contradict, making confusion among health workers. Dr Russo said the distal-medial-proximal Catheter Vein Pressure has no difference but were denied by Susan S. Scott. Proof of postulate is needed as a solution to inward care. Therefore, this study aimed to compare the central vein pressure between distal, medial, and proximal lumens with the water manometer method. Forty-nine samples retrospective study were taken from the distal - medial - proximal Catheter Vein Pressure of the \"zero\" until fifth days. The differences are analyzed with Statistical Paired t Test with p-Value < 0.05 from SPSS ver. 26 to prove the right postulate. 49 samples were concluded to represent of population. Catheter Vein Pressure from day \"zero\" becomes zero difference, the fifth day 91.8% are no difference while the rest have difference of 0.2 - 1.0 cm H2O and the conclusion are no significant difference with 95% CI. The correlation scale of 0.998 and 0.999 proves that the three lumens tend to produce no differences. In conclusion, the distal - medial - proximal Catheter Vein Pressure values in this study have no significant differences and consistent from \"zero\" until fifth days. This is formulated as P distal = P medial = P proximal (cm H2O). Keywords : Central Vein Pressure, Pressure, distal - medial - proximal, no differences, ward patient. Correspondence : sumantrie_medicalgp@yahoo.com","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90720203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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