E. O. Jimmy, M. Mohamed, Sahana Harun, Arman Hadi Fikri
A survey of itchyofauna was done at Sungai Ginseng, located in the interior part of Maliau Basin Conservation Area (MBCA). The diversity of itchyofauna in MBCA was found to be very low. The fiveday survey discovered only two species of fish, Puntius sealei and Hemibagrus nemurus. The abundance of fish in deep pool was higher compared to runs and riffles. The simple fish community found in this study reflects the uniqueness of both the habitat and the fish community surviving in this ecosystem.
{"title":"The itchyofauna of Maliau Basin Conservation Area, Sabah, Malaysia, with special reference to the stream near Ginseng Camp","authors":"E. O. Jimmy, M. Mohamed, Sahana Harun, Arman Hadi Fikri","doi":"10.51200/jtbc.v6i.203","DOIUrl":"https://doi.org/10.51200/jtbc.v6i.203","url":null,"abstract":"A survey of itchyofauna was done at Sungai Ginseng, located in the interior part of Maliau Basin Conservation Area (MBCA). The diversity of itchyofauna in MBCA was found to be very low. The fiveday survey discovered only two species of fish, Puntius sealei and Hemibagrus nemurus. The abundance of fish in deep pool was higher compared to runs and riffles. The simple fish community found in this study reflects the uniqueness of both the habitat and the fish community surviving in this ecosystem.","PeriodicalId":322463,"journal":{"name":"Journal of Tropical Biology & Conservation (JTBC)","volume":"66 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139259190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Voo, N. Lai, Caroline Kibat, Seok Hwa Puah, C. Hew, Kum-Hyung Lee, C. Ho
Maliau Basin is one of the world's hot spot of biodiversity.
马辽河流域是世界生物多样性的热点地区之一。
{"title":"Actinomycetes and Fungi Isolated From Maliau Basin, Sabah and The Screening For Novel Secondary Metabolites Against Eukaryotic Signal Transduction and Mycobacterium","authors":"L. Voo, N. Lai, Caroline Kibat, Seok Hwa Puah, C. Hew, Kum-Hyung Lee, C. Ho","doi":"10.51200/jtbc.v3i.89","DOIUrl":"https://doi.org/10.51200/jtbc.v3i.89","url":null,"abstract":"Maliau Basin is one of the world's hot spot of biodiversity.","PeriodicalId":322463,"journal":{"name":"Journal of Tropical Biology & Conservation (JTBC)","volume":"40 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139259510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A preliminary study was conducted to investigate the occurrence of intestinal parasites in the faeces of captive Malayan tapir in Zoo Negara, Malaysia. A total of 12 fresh faecal samples were collected from three different individuals and screened for eggs and larvae using the sedimentation technique. The results shows that Strongylus sp. infection was the highest with 43 %, followed by Strongyloides sp. and Fasciola sp. with 17 % each, Balantidium sp. 11 %, Ascaris sp. 9 % and unidentified 3 %. Fasciola sp. and Ascaris sp. were found in samples obtained from one individual kept in a cage while Balantidium sp. was found in the free-roaming individuals. Previous information on parasitic diseases in tapir was largely derived from those found in the wild. This study highlights the first record on parasitic infection in captive tapir in Malaysia. In addition, due to pathogenic importance of the parasites to both animals and humans, the population should be closely monitored. Considering the endangered status of the Malayan tapir, further studies are needed to highlight this issue.
{"title":"Preliminary study on the occurrence of intestinal parasites in Malayan tapir (Tapirus indicus) in Zoo Negara, Malaysia","authors":"M. Mustapa, A. Ismail, F. Rahman, Mat Naim Ramli","doi":"10.51200/jtbc.v11i.265","DOIUrl":"https://doi.org/10.51200/jtbc.v11i.265","url":null,"abstract":"A preliminary study was conducted to investigate the occurrence of intestinal parasites in the faeces of captive Malayan tapir in Zoo Negara, Malaysia. A total of 12 fresh faecal samples were collected from three different individuals and screened for eggs and larvae using the sedimentation technique. The results shows that Strongylus sp. infection was the highest with 43 %, followed by Strongyloides sp. and Fasciola sp. with 17 % each, Balantidium sp. 11 %, Ascaris sp. 9 % and unidentified 3 %. Fasciola sp. and Ascaris sp. were found in samples obtained from one individual kept in a cage while Balantidium sp. was found in the free-roaming individuals. Previous information on parasitic diseases in tapir was largely derived from those found in the wild. This study highlights the first record on parasitic infection in captive tapir in Malaysia. In addition, due to pathogenic importance of the parasites to both animals and humans, the population should be closely monitored. Considering the endangered status of the Malayan tapir, further studies are needed to highlight this issue.","PeriodicalId":322463,"journal":{"name":"Journal of Tropical Biology & Conservation (JTBC)","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139257567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
An alticine genus Tamdaoana Medvedev is newly recorded from Malay Peninsula and Borneo, with 2 new species, T. kotakinabaluensis and T. monticola n. spp. A key is provided for 3 known species, but the taxonomic status of the population in Malays Peninsula remains unclear. Further, the genus is suggested to have close similarity to the genus Lanka Maulik.
马来半岛和婆罗洲地区新记录了一种白头翁属植物Tamdaoana Medvedev，其中有2个新种：T. kotakinabaluensis和T. monticola n. spp.提供了3个已知种的检索表，但马来半岛种群的分类地位仍不清楚。此外，该属被认为与兰卡毛利克属十分相似。
{"title":"Genus Tamdaona Medvedev in Malaysia (Coleoptera: Chrysomelidae, Alticinae)","authors":"Haruo Takizawa","doi":"10.51200/jtbc.v11i.264","DOIUrl":"https://doi.org/10.51200/jtbc.v11i.264","url":null,"abstract":"An alticine genus Tamdaoana Medvedev is newly recorded from Malay Peninsula and Borneo, with 2 new species, T. kotakinabaluensis and T. monticola n. spp. A key is provided for 3 known species, but the taxonomic status of the population in Malays Peninsula remains unclear. Further, the genus is suggested to have close similarity to the genus Lanka Maulik.","PeriodicalId":322463,"journal":{"name":"Journal of Tropical Biology & Conservation (JTBC)","volume":"290 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139257015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A study on planktonic primary production was conducted in three Indonesian embayments subjected to different levels of eutrophication. The three embayments are Jakarta, Lampung and Semangka Bay. A previous study revealed that Jakarta Bay is heavily eutrophied while Lampung Bay is moderately eutrophied and Semangka Bay is close to pristine conditions. The eutrophication state in the three bays studied was closely related with respective nutrient loading of the embayments. Annual primary production in Jakarta Bay ranged from 47 to 503 g C m-2 y-1, in Lampung Bay from 31 to 196 g C m-2 y-1 and in Semangka Bay from 14 to 40 g C m-2 y-1. Spatial gradients in primary productivity were closely related to spatial nutrient gradients in the bays, except in Semangka Bay, due to the high turbidity of the river mouth. Temporal variability in primary productivity was small, consistent with small changes in environmental parameters across seasons. Jakarta Bay which has the most eutrophied waters was the highest in terms of primary productivity, followed by Lampung Bay and Semangka Bay. The primary productivity levels in the three bays was closely related with levels of nutrient loadings. This research is of importance for the development of primary production measurement in Indonesia since it is among that uses the radiocarbon technique.
对印度尼西亚三个富营养化程度不同的海湾进行了浮游初级生产研究。这三个海湾分别是雅加达湾、楠榜湾和三芒卡湾。先前的一项研究表明，雅加达湾富营养化程度严重，楠榜湾富营养化程度适中，而塞芒卡湾则接近原始状态。所研究的三个海湾的富营养化状况与各自海湾的营养负荷密切相关。雅加达湾的年初级生产力从 47 克 C m-2 y-1 到 503 克 C m-2 y-1 不等，楠榜湾从 31 克 C m-2 y-1 到 196 克 C m-2 y-1 不等，三芒卡湾从 14 克 C m-2 y-1 到 40 克 C m-2 y-1 不等。初级生产力的空间梯度与海湾的空间营养梯度密切相关，但三芒卡湾除外，因为河口的浊度较高。初级生产力的时间变化较小，这与不同季节环境参数的微小变化是一致的。雅加达湾水域富营养化程度最高，初级生产力也最高，其次是楠榜湾和三芒卡湾。这三个海湾的初级生产力水平与营养负荷水平密切相关。这项研究对印度尼西亚初级生产力测量的发展具有重要意义，因为它是使用放射性碳技术的研究之一。
{"title":"Effects of different nutrient loadings on planktonic primary production in embayments of Indonesia","authors":"Ario Damar, Franciscus Colijn, K. Hesse","doi":"10.51200/jtbc.v11i.263","DOIUrl":"https://doi.org/10.51200/jtbc.v11i.263","url":null,"abstract":"A study on planktonic primary production was conducted in three Indonesian embayments subjected to different levels of eutrophication. The three embayments are Jakarta, Lampung and Semangka Bay. A previous study revealed that Jakarta Bay is heavily eutrophied while Lampung Bay is moderately eutrophied and Semangka Bay is close to pristine conditions. The eutrophication state in the three bays studied was closely related with respective nutrient loading of the embayments. Annual primary production in Jakarta Bay ranged from 47 to 503 g C m-2 y-1, in Lampung Bay from 31 to 196 g C m-2 y-1 and in Semangka Bay from 14 to 40 g C m-2 y-1. Spatial gradients in primary productivity were closely related to spatial nutrient gradients in the bays, except in Semangka Bay, due to the high turbidity of the river mouth. Temporal variability in primary productivity was small, consistent with small changes in environmental parameters across seasons. Jakarta Bay which has the most eutrophied waters was the highest in terms of primary productivity, followed by Lampung Bay and Semangka Bay. The primary productivity levels in the three bays was closely related with levels of nutrient loadings. This research is of importance for the development of primary production measurement in Indonesia since it is among that uses the radiocarbon technique.","PeriodicalId":322463,"journal":{"name":"Journal of Tropical Biology & Conservation (JTBC)","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139258886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. H. Abdullah, Ramzah Dambul, M. Mohamed, Sahana Harun
Surface water quality was examined to determine spatial and seasonal variations in the Lower Kinabatangan River catchment, Sabah, Malaysia between October 2004 and June 2005, during the weak La Niña event. The study sought to distinguish between the quality in surface waters draining from an oil palm plantation (OP), a secondary forest (SF) and an oxbow lake (OB); and to identify its seasonal variability. A total of 45 samples were collected during fieldwork campaigns that spanned over the inter-monsoonal period, wet and dry seasons. The Water Quality Index (WQI) was calculated and analysed based on the Malaysia Interim National Water Quality Standard (INWQS). Results show that the quality of the river fall into Class II or moderate level. Discriminant analysis (DA) has been employed to classify independent variables into mutually-exclusive groups. Suspended sediment (SS) and chemical oxygen demand (COD) parameters were found higher during the wet season. COD was found dominant in stream located within the oil palm plantation, whilst SS was dominant in oxbow lake. Surface water quality variations could be influenced by weak La Niña event in 2005/2006, as precipitation anomalies have been observed during the sampling campaign.
{"title":"Spatial and seasonal variations in surface water quality of the Lower Kinabatangan River Catchment, Sabah, Malaysia","authors":"M. H. Abdullah, Ramzah Dambul, M. Mohamed, Sahana Harun","doi":"10.51200/jtbc.v11i.267","DOIUrl":"https://doi.org/10.51200/jtbc.v11i.267","url":null,"abstract":"Surface water quality was examined to determine spatial and seasonal variations in the Lower Kinabatangan River catchment, Sabah, Malaysia between October 2004 and June 2005, during the weak La Niña event. The study sought to distinguish between the quality in surface waters draining from an oil palm plantation (OP), a secondary forest (SF) and an oxbow lake (OB); and to identify its seasonal variability. A total of 45 samples were collected during fieldwork campaigns that spanned over the inter-monsoonal period, wet and dry seasons. The Water Quality Index (WQI) was calculated and analysed based on the Malaysia Interim National Water Quality Standard (INWQS). Results show that the quality of the river fall into Class II or moderate level. Discriminant analysis (DA) has been employed to classify independent variables into mutually-exclusive groups. Suspended sediment (SS) and chemical oxygen demand (COD) parameters were found higher during the wet season. COD was found dominant in stream located within the oil palm plantation, whilst SS was dominant in oxbow lake. Surface water quality variations could be influenced by weak La Niña event in 2005/2006, as precipitation anomalies have been observed during the sampling campaign.","PeriodicalId":322463,"journal":{"name":"Journal of Tropical Biology & Conservation (JTBC)","volume":"210 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139259283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yosuke Otani, Augustine Tuuga, Henry Bernard, Ikki Matsuda
We report two cases of predation and predation-related events on long-tailed macaques and proboscis monkeys living in sympatry in the lower Kianabatangan, Sabah, Malaysia.
我们报告了两起长尾猕猴和长鼻猴在马来西亚沙巴州基亚纳巴丹干下游共生的捕食和捕食相关事件。
{"title":"Opportunistic predation and predation-related events on long-tailed macaque and proboscis monkey in Kinabatangan, Sabah, Malaysia","authors":"Yosuke Otani, Augustine Tuuga, Henry Bernard, Ikki Matsuda","doi":"10.51200/jtbc.v9i2.247","DOIUrl":"https://doi.org/10.51200/jtbc.v9i2.247","url":null,"abstract":"We report two cases of predation and predation-related events on long-tailed macaques and proboscis monkeys living in sympatry in the lower Kianabatangan, Sabah, Malaysia.","PeriodicalId":322463,"journal":{"name":"Journal of Tropical Biology & Conservation (JTBC)","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139259640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The wild ginger, Tuhau, E. coccinea is a plant species from Etlingera genus and Zingiberaceae family. This study is focused on a reviewed paper reported on the extraction method used to derive essential oils and the overview of the published data regarding medicinal properties of Etlingera coccinea spp. The search was performed in several databases such as ScienceDirect, Scopus, SpringerLink, and Researchgate and also Google Scholar. The following keywords were used individually and or in combination “E. coccinea” and “Tuhau”. This article highlights the extraction techniques used to derive the essential oil of E. coccinea and also provide briefly overview of the medicinal properties from the data in recent literature.
{"title":"A Review of Etlingera coccinea (Blume) S. Sakai and Nagam (Zingiberaceae) on Achievement of Producing An Essential Oil and Medicinal Properties in Sabah, East Malaysia.","authors":"Emmeldah Joseph, Elia Godoong","doi":"10.51200/jtbc.v20i.4668","DOIUrl":"https://doi.org/10.51200/jtbc.v20i.4668","url":null,"abstract":"The wild ginger, Tuhau, E. coccinea is a plant species from Etlingera genus and Zingiberaceae family. This study is focused on a reviewed paper reported on the extraction method used to derive essential oils and the overview of the published data regarding medicinal properties of Etlingera coccinea spp. The search was performed in several databases such as ScienceDirect, Scopus, SpringerLink, and Researchgate and also Google Scholar. The following keywords were used individually and or in combination “E. coccinea” and “Tuhau”. This article highlights the extraction techniques used to derive the essential oil of E. coccinea and also provide briefly overview of the medicinal properties from the data in recent literature.","PeriodicalId":322463,"journal":{"name":"Journal of Tropical Biology & Conservation (JTBC)","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139318575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Globally, seagrass meadows have declined due to environmental factors and human activities, particularly by limiting light to seagrass in turbid coastal waters. Furthermore, publications of seagrass research findings from the Southeast Asia region are scarce, making understanding these habitats difficult despite their ecological and economic importance. This research aimed to provide mean and standard deviation of seagrass morphology, as well as to examine the morphology structures in response to water depth. Samples of two species of seagrass, Halodule uninervis and Halophila ovalis, were collected by using random sampling in a line transect at Pulau Besar and Pulau Tinggi in Johor, southern Malaysia, in September 2013 and April 2014. Six morphological features of each seagrass species were measured physically using CPCe software and the relationship of water depth to seagrass were evaluated using Pearson’s Correlation. The result highlights that the leaf and root morphology is larger in Pulau Tinggi because it is nearer to the Johor mainland, where the introduction of nutrients from economic activity positively influence seagrass growth. The overall morphology structures of both species in both islands are greater in 2013 than 2014. For the relationship with water depth, it had greater positive relationship to H. univervis leaf width (r = 0.7532), internode width (r = 0.6722), leaf length (r = 0.5739); whereas for H. ovalis, water depth was correlated strongly with leaf width (r = 0.6697) and leaf surface area (r = 0.6313). The morphology of seagrass species varies depending on habitat conditions, this study can fill knowledge gaps, but more fundamental research on seagrass meadows is required particularly for the seagrasses in the Southeast Asia marine region.
在全球范围内，由于环境因素和人类活动，特别是在浑浊的沿海水域限制了海草的光照，海草草甸已经减少。此外，东南亚地区有关海草研究成果的出版物很少，尽管这些生境具有重要的生态和经济价值，但却很难了解它们。本研究旨在提供海草形态的平均值和标准偏差，并考察形态结构对水深的响应。研究人员于 2013 年 9 月和 2014 年 4 月在马来西亚南部柔佛州的 Pulau Besar 和 Pulau Tinggi 采用随机取样的方法收集了两种海草（Halodule uninervis 和 Halophila ovalis）的样本。使用 CPCe 软件对每个海草物种的六个形态特征进行了物理测量，并使用皮尔逊相关性评估了水深与海草的关系。结果表明，Pulau Tinggi 的叶片和根部形态较大，这是因为它靠近柔佛州大陆，经济活动带来的营养物质对海草的生长有积极影响。这两个岛屿的两个物种的整体形态结构在 2013 年都大于 2014 年。就与水深的关系而言，水深与 H. univervis 的叶宽（r = 0.7532）、节间宽度（r = 0.6722）、叶长（r = 0.5739）有较大的正相关关系；而对于 H. ovalis，水深与叶宽（r = 0.6697）和叶表面积（r = 0.6313）密切相关。海草物种的形态因生境条件而异，这项研究可以填补知识空白，但还需要对海草草甸进行更多的基础研究，特别是针对东南亚海洋区域的海草。
{"title":"Influence of Water Depth on the Morphology Structure of Seagrass from the Southern of Peninsular Malaysia","authors":"Ng Kah Choon","doi":"10.51200/jtbc.v20i.4658","DOIUrl":"https://doi.org/10.51200/jtbc.v20i.4658","url":null,"abstract":"Globally, seagrass meadows have declined due to environmental factors and human activities, particularly by limiting light to seagrass in turbid coastal waters. Furthermore, publications of seagrass research findings from the Southeast Asia region are scarce, making understanding these habitats difficult despite their ecological and economic importance. This research aimed to provide mean and standard deviation of seagrass morphology, as well as to examine the morphology structures in response to water depth. Samples of two species of seagrass, Halodule uninervis and Halophila ovalis, were collected by using random sampling in a line transect at Pulau Besar and Pulau Tinggi in Johor, southern Malaysia, in September 2013 and April 2014. Six morphological features of each seagrass species were measured physically using CPCe software and the relationship of water depth to seagrass were evaluated using Pearson’s Correlation. The result highlights that the leaf and root morphology is larger in Pulau Tinggi because it is nearer to the Johor mainland, where the introduction of nutrients from economic activity positively influence seagrass growth. The overall morphology structures of both species in both islands are greater in 2013 than 2014. For the relationship with water depth, it had greater positive relationship to H. univervis leaf width (r = 0.7532), internode width (r = 0.6722), leaf length (r = 0.5739); whereas for H. ovalis, water depth was correlated strongly with leaf width (r = 0.6697) and leaf surface area (r = 0.6313). The morphology of seagrass species varies depending on habitat conditions, this study can fill knowledge gaps, but more fundamental research on seagrass meadows is required particularly for the seagrasses in the Southeast Asia marine region.","PeriodicalId":322463,"journal":{"name":"Journal of Tropical Biology & Conservation (JTBC)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139318698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A herbal medicinal plant known as Andrographis paniculata, or "hempedu bumi," is recognised for its numerous medicinal properties and role in promoting community health. Despite its widespread use, the potential nephroprotective effects and underlying mechanism of action of Andrographis paniculata remain unexplored. To address this gap, the present study aimed to investigate the nephroprotective effects of Andrographis paniculata against renal oxidative damage induced by carbon tetrachloride (CCl4) in rats. Sprague-Dawley rats were pre-treated with Andrographis paniculata extract via gavage (100, 200, and 300 mg/kg b.w., respectively) once daily for 14 days, followed by two doses of CCl4 (1.2 ml/kg b.w.) on the 13th and 14th days. After two weeks, rats were sacrificed, and a nephroprotective analysis was performed. CCl4 administration at a dose of 1.2 ml/kg body weight resulted in oxidative stress in the renal system, as evidenced by elevated lipid peroxidation levels (TBARS). This oxidative stress was accompanied by a significant decrease in the activities of antioxidant enzymes and a depletion in the levels of reduced glutathione (p<0.05). Histopathological examination confirmed the impairment of renal function. Andrographis paniculata significantly mitigated the majority of these alterations. Based on our research, the nephroprotective advantages of Andrographis paniculata can be attributed to its ability to act as an antioxidant and scavenge free radicals.
{"title":"Effects of Andrographis paniculata on Carbon Tetrachloride (CCl4)-Mediated Renal Oxidative Damage in Rats","authors":"Mohammad Iqbal, Senty Vun-Sang, P. Koh","doi":"10.51200/jtbc.v20i.4667","DOIUrl":"https://doi.org/10.51200/jtbc.v20i.4667","url":null,"abstract":"A herbal medicinal plant known as Andrographis paniculata, or \"hempedu bumi,\" is recognised for its numerous medicinal properties and role in promoting community health. Despite its widespread use, the potential nephroprotective effects and underlying mechanism of action of Andrographis paniculata remain unexplored. To address this gap, the present study aimed to investigate the nephroprotective effects of Andrographis paniculata against renal oxidative damage induced by carbon tetrachloride (CCl4) in rats. Sprague-Dawley rats were pre-treated with Andrographis paniculata extract via gavage (100, 200, and 300 mg/kg b.w., respectively) once daily for 14 days, followed by two doses of CCl4 (1.2 ml/kg b.w.) on the 13th and 14th days. After two weeks, rats were sacrificed, and a nephroprotective analysis was performed. CCl4 administration at a dose of 1.2 ml/kg body weight resulted in oxidative stress in the renal system, as evidenced by elevated lipid peroxidation levels (TBARS). This oxidative stress was accompanied by a significant decrease in the activities of antioxidant enzymes and a depletion in the levels of reduced glutathione (p<0.05). Histopathological examination confirmed the impairment of renal function. Andrographis paniculata significantly mitigated the majority of these alterations. Based on our research, the nephroprotective advantages of Andrographis paniculata can be attributed to its ability to act as an antioxidant and scavenge free radicals.","PeriodicalId":322463,"journal":{"name":"Journal of Tropical Biology & Conservation (JTBC)","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139318840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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