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Prevalence and determinants of obesity among school going adolescents: A systematic review 在校青少年肥胖的患病率和决定因素:一项系统综述
Pub Date : 2023-04-01 DOI: 10.17727/jmsr.2023/11-26
Mangrola N, P. K, Patel Pk, Chauhan D, P. N
Adolescence is considered as critical period for the development of obesity. The frequency of childhood obesity has increased over the last 3 decades, and it has emerged as a public health concern in multiple places around the world. A number of factors interact in a complex way to cause obesity, which is still not fully understood. Therefore, the purpose of this review was to identify and assess the scientific literature on the prevalence of obesity, and behavioural, contextual and biological factors associated with obesity in adolescents. The search was carried out using PubMed, Web of Science, Embase and Scopus considering articles published from the establishment of the databanks until December, 2022. Data on the prevalence of overweight and obesity among children and adolescents, and articles on the determinants and factors affecting obesity were reviewed. The results obtained and the association observed among the factors studied will be helpful to support the planning, implementation and evaluation of preventive activities and interventions. Keywords: adolescents; childhood; intervention; obesity; overweight
青春期被认为是肥胖发展的关键时期。在过去的30年里,儿童肥胖的频率有所增加,并在世界各地的许多地方成为一个公共卫生问题。许多因素以一种复杂的方式相互作用,导致肥胖,这一点仍未完全了解。因此,本综述的目的是识别和评估有关青少年肥胖患病率以及与肥胖相关的行为、环境和生物学因素的科学文献。检索使用PubMed、Web of Science、Embase和Scopus进行,考虑了从数据库建立到2022年12月发表的文章。回顾了儿童和青少年中超重和肥胖流行率的数据,以及影响肥胖的决定因素和因素的文章。所获得的结果和所研究的因素之间的联系将有助于支持预防活动和干预措施的规划、实施和评价。关键词:青少年;童年;干预;肥胖;超重
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引用次数: 0
The predictive significance of ratio between white blood cells count and serum albumin in assessing the functional outcome of acute ischemic stroke 白细胞计数与血清白蛋白比值在评估急性缺血性脑卒中功能转归中的预测意义
Pub Date : 2023-04-01 DOI: 10.17727/jmsr.2023/11-23
Krishnamurthy ha, Bharathi S, Roja gT
Introduction: The acute ischemic infarction is associated with significant damage to brain parenchyma, where the high degree of acute inflammation is found. This work aimed to study the predictive value of ratio between blood WBCs and serum albumin levels in assessing the functional outcome in subjects with acute ischemic stroke. Materials and methods: A prospective observational study was conducted on 223 subjects from February 2022 to August 2022 at K.R. Hospital, Mysore. The data collected from patients of acute ischemic stroke, with the onset of stroke within 24 hours. Severity of stroke was assessed by using National Institute of Health Stroke Scale (NIHSS) at the time of admission. Data was collected using a pretested proforma meeting the objectives of the study. Results: The study has 124(55.6%) male and 99(44.4%) of female patients. Most of the patients (65%) were in the age group of more than 66 years. Most of the patients i.e., 66 (29.6%) had moderate to severe stroke at presentation as assessed by NIHSS stroke scale. At the end of third month of follow up, the acute ischemic stroke patients with MRS of >3 had WBCs count/serum albumin ratio of 4361.1 (p value - 0.001). Conclusion: The significant acute inflammation is found in acute ischemic stroke and it may be one of the causes of poor outcome and disability in so many ischemic stroke patients. This study once again endorses the use of high intensive statins and adequate dose of antiplatelet agents as early as possible in acute ischemic stroke patients. Keywords: acute ischemic stroke; WBCs; Modified Rankin Scale; NIHSS; serum albumin
简介:急性缺血性梗死伴明显脑实质损伤,脑实质可见高度急性炎症。本研究旨在研究血白细胞与血清白蛋白水平比值在评估急性缺血性脑卒中患者功能结局中的预测价值。材料与方法:于2022年2月至2022年8月在迈索尔K.R.医院对223名受试者进行前瞻性观察研究。数据采集自急性缺血性脑卒中患者,卒中发作时间在24小时内。入院时采用美国国立卫生研究院卒中量表(NIHSS)评估卒中严重程度。使用符合研究目标的预测试形式收集数据。结果:男性124例(55.6%),女性99例(44.4%)。大多数患者(65%)年龄在66岁以上。根据NIHSS卒中量表,66例(29.6%)患者就诊时为中度至重度卒中。随访第3个月时,MRS为bbbb3的急性缺血性脑卒中患者白细胞计数/血清白蛋白比值为4361.1 (p值- 0.001)。结论:急性缺血性脑卒中患者存在明显的急性炎症反应,这可能是众多缺血性脑卒中患者预后不良和致残的原因之一。本研究再次支持在急性缺血性卒中患者中尽早使用高强度他汀类药物和足剂量抗血小板药物。关键词:急性缺血性脑卒中;白细胞;改良Rankin量表;署;血清白蛋白
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引用次数: 0
Outcomes of early and interval laparoscopic cholecystectomy for acute cholecystitis at a teaching hospital in Kerala: A prospective observational comparative study 喀拉拉邦一家教学医院急性胆囊炎早期和间歇腹腔镜胆囊切除术的疗效:一项前瞻性观察性比较研究
Pub Date : 2023-04-01 DOI: 10.17727/jmsr.2023/11-13
Thomas J, Oommen An, M. J, A. V., Joy Rr
Timing of laparoscopic cholecystectomy, a widely used treatment modality for acute cholecystitis remains controversial. This prospective observational comparative study investigated patient outcomes for early (ELC) and interval laparoscopic cholecystectomy (ILC) in patients with acute cholecystitis admitted to the General Surgery Department at a tertiary care centre in Thrissur, Kerala, between December 2018 and June 2020. Of 67 patients, 34 were assigned to ELC and 33 to ILC groups and followed up for 2 weeks post-surgery. Patient characteristics, clinical features, investigations, intra operative details and post operative outcomes were tabulated. Comparison of age was statistically analyzed using student’s ‘t’ test, demographics and morbidity data using Fisher’s exact test/ Chi-square test and length of hospital stay using Mann Whitney U test. Mean age was significantly higher in the ILC group. 66% of study participants were females with a higher proportion of females observed in the ILC group. Post-surgical complications were not significantly higher in ELC group compared to ILC group. Total length of hospital stay was significantly longer in the ILC group than in ELC group (10.2 ±4.5 vs. 7.1 ±3.0) days, p value: 0.001). Duration of hospital stay for the laparoscopic cholecystectomy procedure taken separately, was longer in ELC group comparatively, 7 ±3.01 versus 4 ±-2.38, (p value: <0.001). There was no mortality. It was observed in the present study that ELC is preferable to ILC for acute cholecystitis with added benefit of shorter hospital stay. Further large randomized trials would be valuable to make recommendations for future management. Keywords: acute cholecystitis; laparoscopic cholecystectomy; hospital stay; conversion rate
腹腔镜胆囊切除术是一种广泛应用于急性胆囊炎的治疗方式,其时间安排仍有争议。这项前瞻性观察性比较研究调查了2018年12月至2020年6月期间入住喀拉拉邦Thrissur三级护理中心普通外科的急性胆囊炎患者早期(ELC)和间隔期腹腔镜胆囊切除术(ILC)的患者结果。在67名患者中,34名患者被分配到ELC组,33名被分配到ILC组,并在术后随访2周。将患者特征、临床特征、调查、术中细节和术后结果制成表格。使用学生t检验、Fisher精确检验/卡方检验的人口统计和发病率数据以及Mann-Whitney U检验的住院时间进行年龄比较的统计分析。ILC组的平均年龄明显较高。66%的研究参与者是女性,ILC组中观察到的女性比例更高。与ILC组相比,ELC组的术后并发症并不显著增加。ILC组的总住院时间明显长于ELC组(10.2±4.5 vs.7.1±3.0)天,p值:0.001)。单独进行腹腔镜胆囊切除术的住院时间相对较长,ELC组为7±3.01 vs.4±-2.38(p值:<0.001)。无死亡率。在本研究中观察到,对于急性胆囊炎,ELC比ILC更可取,而且住院时间更短。进一步的大型随机试验将有助于为未来的管理提出建议。关键词:急性胆囊炎;腹腔镜胆囊切除术;住院;转化率
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引用次数: 0
Post COVID-19 mucormycosis- histopathology and associated factors 新冠肺炎后毛霉菌病-组织病理学和相关因素
Pub Date : 2023-04-01 DOI: 10.17727/jmsr.2023/11-16
P. S, Khade M, A. S, K. S, S. D
Introduction: SARS-COV-2 infection (COVID-19) may be associated with wide range of bacterial and fungal infections. Mucormycosis is a common and potentially life threatening opportunistic fungal infection responsible for morbidity and mortality. Many factors like diabetes mellitus, hypertension and corticosteroid therapy might have been a role in the immunocompromised state of the patients. The aim of present study was to know the predisposing factors and role of histopathology in diagnosis and assessing the prognosis of post COVID-19 mucormycosis cases. Material and methods: It is a prospective observational study conducted in tertiary care hospital over a period of 6 months from April 2021 to September 2021. Functional endoscopic sinus surgery (FESS) and maxillectomy samples from 157 post COVID-19 mucormycosis suspected cases were studied and details regarding history of diabetes mellitus, hypertension and corticosteroid therapy were retrieved. All tissue samples were examined under H&E stain and special fungal stain (PAS). Results: On histopathological examination, out of total 157 cases, 94 cases were found to be positive for mucormycosis. Of these 94 cases, 63 were males and 31 were females. Age range was from 23 to 75 years. 5 cases showed mixed mucormycosis and aspergillosis infection. Also out of 94 post COVID mucormycosis cases, 72 were diabetic, 21 were hypertensive and 68 had a history of corticosteroid intake for treatment of COVID-19 infection. Conclusion: Histopathology plays a pivotal role in accurate diagnosis and assessing the severity and invasiveness of mucormycosis. Diabetes mellitus and corticosteroid use are the important associated factors. Keywords: post COVID -19; mucormycosis; daibetes; steroid therapy
SARS-COV-2感染(COVID-19)可能与多种细菌和真菌感染有关。毛霉病是一种常见的和潜在威胁生命的机会性真菌感染负责发病率和死亡率。许多因素,如糖尿病、高血压和皮质类固醇治疗可能是患者免疫功能低下的原因。本研究的目的是了解COVID-19后毛霉菌病的易感因素及组织病理学在诊断和评估预后中的作用。材料与方法:前瞻性观察性研究,于2021年4月至2021年9月在三级医院进行,为期6个月。对157例疑似COVID-19毛霉菌病患者进行功能性内镜鼻窦手术(FESS)和上颌切除术,并检索糖尿病、高血压和皮质类固醇治疗史的详细资料。所有组织标本在H&E染色和特殊真菌染色(PAS)下检查。结果:157例患者的组织病理学检查中,毛霉病阳性94例。在这94例病例中,男性63例,女性31例。年龄从23岁到75岁不等。5例为毛霉病与曲霉病混合感染。此外,在94例新冠肺炎后毛霉菌病病例中,72例为糖尿病,21例为高血压,68例为治疗新冠肺炎感染而服用皮质类固醇。结论:组织病理学对毛霉病的准确诊断、严重程度及侵袭性评估具有重要意义。糖尿病和皮质类固醇的使用是重要的相关因素。关键词:新冠肺炎后;毛霉菌病;daibetes;类固醇治疗
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引用次数: 0
Effect of fenugreek (Trigonella foenum-graecum) seed powder on lipid profile: A single blind placebo controlled study 胡芦巴(胡芦巴)籽粉对脂质的影响:一项单盲安慰剂对照研究
Pub Date : 2023-04-01 DOI: 10.17727/jmsr.2023/11-22
Amit A, Shubhangi V, A. D., Neel C, Kasturi B
Background: Dyslipidemia is one of the most prevalent risk factors contributing to atherosclerotic cardiovascular disease. Clinical trials have demonstrated that treatment of dyslipidemia reduces cardiovascular events. Fenugreek seed powder supplementation has lipid-lowering activity, but has not been studied extensively. In light of this, we undertook the present study at tertiary care hospital in Amravati, Maharashtra, with the aim of studying the effect of fenugreek seed powder on serum lipid profile in patients with dyslipidemia & to determine the adverse effects of it. Methods: The study was a single blind placebo controlled study conducted on 60 patients with dyslipidemia from June 2022 to November 2022, after meeting inclusion and exclusion criteria. Results: It was found significant decrease in serum total cholesterol (237.32 to 204.51mg/dl) p value <0.001, serum LDL cholesterol (154.69 to 133.88 mg/dl) p value < 0.001 & serum triglycerides (196.95 to 165.09 mg/dl) p <0.01 with no effect on serum HDL cholesterol (41.11 to 38.92mg/dl) p >0.05, without any major side effects. Conclusion: Fenugreek seed powder significantly lowers serum total cholesterol, LDL cholesterol and triglyceride levels in dyslipidemia patients, with no effect on serum HDL cholesterol levels. fenugreek seed powder supplementation considerably improves lipid Profile. Hence it could be well-thought-out as an effective lipid lowering nutritional supplement. Further high quality & large scale studies are needed to decisively establish the clinical efficacy of fenugreek seed powder. Keywords: fenugreek seed powder; dyslipidemia; lipid profile; cholesterol; LDL; triglycerides; HDL
背景:血脂异常是导致动脉粥样硬化性心血管疾病的最常见的危险因素之一。临床试验表明,治疗血脂异常可以减少心血管事件。胡芦巴籽粉具有降脂活性,但尚未得到广泛研究。有鉴于此,我们在马哈拉施特拉邦阿姆拉瓦蒂的三级护理医院进行了本研究,目的是研究胡芦巴籽粉对血脂异常患者血脂谱的影响,并确定其不良影响。方法:该研究是一项单盲安慰剂对照研究,于2022年6月至2022年11月对60名血脂异常患者进行,符合入选和排除标准后。结果:血清总胆固醇(237.32~204.51mg/dl)显著下降,p值0.05,无明显副作用。结论:胡芦巴籽粉能显著降低血脂异常患者血清总胆固醇、低密度脂蛋白胆固醇和甘油三酯水平,对血清高密度脂蛋白水平无影响。胡芦巴籽粉的补充显著改善了脂质状况。因此,它可以被认为是一种有效的降脂营养补充剂。需要进一步的高质量和大规模研究来决定性地确定胡芦巴籽粉的临床疗效。关键词:胡芦巴籽粉;血脂异常;脂质概况;胆固醇LDL;甘油三酯;HDL
{"title":"Effect of fenugreek (Trigonella foenum-graecum) seed powder on lipid profile: A single blind placebo controlled study","authors":"Amit A, Shubhangi V, A. D., Neel C, Kasturi B","doi":"10.17727/jmsr.2023/11-22","DOIUrl":"https://doi.org/10.17727/jmsr.2023/11-22","url":null,"abstract":"Background: Dyslipidemia is one of the most prevalent risk factors contributing to atherosclerotic cardiovascular disease. Clinical trials have demonstrated that treatment of dyslipidemia reduces cardiovascular events. Fenugreek seed powder supplementation has lipid-lowering activity, but has not been studied extensively. In light of this, we undertook the present study at tertiary care hospital in Amravati, Maharashtra, with the aim of studying the effect of fenugreek seed powder on serum lipid profile in patients with dyslipidemia & to determine the adverse effects of it. Methods: The study was a single blind placebo controlled study conducted on 60 patients with dyslipidemia from June 2022 to November 2022, after meeting inclusion and exclusion criteria. Results: It was found significant decrease in serum total cholesterol (237.32 to 204.51mg/dl) p value <0.001, serum LDL cholesterol (154.69 to 133.88 mg/dl) p value < 0.001 & serum triglycerides (196.95 to 165.09 mg/dl) p <0.01 with no effect on serum HDL cholesterol (41.11 to 38.92mg/dl) p >0.05, without any major side effects. Conclusion: Fenugreek seed powder significantly lowers serum total cholesterol, LDL cholesterol and triglyceride levels in dyslipidemia patients, with no effect on serum HDL cholesterol levels. fenugreek seed powder supplementation considerably improves lipid Profile. Hence it could be well-thought-out as an effective lipid lowering nutritional supplement. Further high quality & large scale studies are needed to decisively establish the clinical efficacy of fenugreek seed powder. Keywords: fenugreek seed powder; dyslipidemia; lipid profile; cholesterol; LDL; triglycerides; HDL","PeriodicalId":32890,"journal":{"name":"Journal of Medical and Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43430127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relation of COVID-19 with acute ischemic bowel disease: A retrospective observational study 新冠肺炎与急性缺血性肠病的关系:一项回顾性观察研究
Pub Date : 2023-04-01 DOI: 10.17727/jmsr.2023/11-21
Takalkar Yp, Ban Sb, Annabathina R, Shinde Ph, Pramod S, Diwewar V, C. A., Rajesha K
Introduction: COVID-19 is a serious respiratory disease caused by SARS-CoV-2, aside from the respiratory system, the gastrointestinal system is the most common site of SARS-COV-2 infection. The study aimed to assess relation between COVID and ischemic bowel disease by analysing length of hospital stay and mortality rates between COVID and non-COVID groups. Methods: The study was conducted from June 2020 to November 2021 in the surgical wards of Seth GS Medical College and KEM Hospital, Mumbai. Included patients presented to emergency room with acute abdomen which diagnosed as acute ischemic bowel disease during the period of study and then compared the outcomes between COVID and non-COVID groups. Results: Out of 40 patients, 16 had no history of COVID and remaining 24 had either previous history of COVID or diagnosed presently with COVID. In both COVID and non-COVID population, distribution of comorbidities were almost equal exception being stroke, where both the cases had previous history of COVID, diabetes was the most common comorbidity in both the groups followed by hypertension. Patients with active COVID infection had higher mortality of 75% (3 out of 4) followed by patients with past history of infection with mortality rate of 65% (13 out of 20) whereas the mortality rate in non-COVID patients were 37.5% (6 out of 16). Conclusion: Ischemic bowel disease among COVID-19 patients is rare, but its association with high mortality rates and prolonged length of stay necessitates clinical suspicion and prompt intervention. Keywords: COVID-19; ischemic bowel disease; acute mesenteric ischemia
简介:COVID-19是由SARS-CoV-2引起的严重呼吸道疾病,除呼吸系统外,胃肠道系统是SARS-CoV-2最常见的感染部位。该研究旨在通过分析COVID组和非COVID组的住院时间和死亡率来评估COVID与缺血性肠病之间的关系。方法:研究于2020年6月至2021年11月在孟买Seth GS医学院和KEM医院的外科病房进行。纳入在研究期间就诊于急诊室的急腹症诊断为急性缺血性肠病的患者,然后比较COVID组和非COVID组的结果。结果:40例患者中16例无新冠肺炎病史,其余24例既往有新冠肺炎病史或现确诊为新冠肺炎。在COVID和非COVID人群中,合并症的分布几乎相同,除了卒中,这两个病例都有先前的COVID病史,糖尿病是两组中最常见的合并症,其次是高血压。活动性COVID感染患者的死亡率较高,为75%(3 / 4),其次是既往感染史患者,死亡率为65%(13 / 20),而非COVID患者的死亡率为37.5%(6 / 16)。结论:缺血性肠病在COVID-19患者中罕见,但其死亡率高,住院时间长,需要临床怀疑并及时干预。关键词:COVID-19;缺血性肠病;急性肠系膜缺血
{"title":"Relation of COVID-19 with acute ischemic bowel disease: A retrospective observational study","authors":"Takalkar Yp, Ban Sb, Annabathina R, Shinde Ph, Pramod S, Diwewar V, C. A., Rajesha K","doi":"10.17727/jmsr.2023/11-21","DOIUrl":"https://doi.org/10.17727/jmsr.2023/11-21","url":null,"abstract":"Introduction: COVID-19 is a serious respiratory disease caused by SARS-CoV-2, aside from the respiratory system, the gastrointestinal system is the most common site of SARS-COV-2 infection. The study aimed to assess relation between COVID and ischemic bowel disease by analysing length of hospital stay and mortality rates between COVID and non-COVID groups. Methods: The study was conducted from June 2020 to November 2021 in the surgical wards of Seth GS Medical College and KEM Hospital, Mumbai. Included patients presented to emergency room with acute abdomen which diagnosed as acute ischemic bowel disease during the period of study and then compared the outcomes between COVID and non-COVID groups. Results: Out of 40 patients, 16 had no history of COVID and remaining 24 had either previous history of COVID or diagnosed presently with COVID. In both COVID and non-COVID population, distribution of comorbidities were almost equal exception being stroke, where both the cases had previous history of COVID, diabetes was the most common comorbidity in both the groups followed by hypertension. Patients with active COVID infection had higher mortality of 75% (3 out of 4) followed by patients with past history of infection with mortality rate of 65% (13 out of 20) whereas the mortality rate in non-COVID patients were 37.5% (6 out of 16). Conclusion: Ischemic bowel disease among COVID-19 patients is rare, but its association with high mortality rates and prolonged length of stay necessitates clinical suspicion and prompt intervention. Keywords: COVID-19; ischemic bowel disease; acute mesenteric ischemia","PeriodicalId":32890,"journal":{"name":"Journal of Medical and Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45154735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 associated mucormycosis at territory care hospital in South India - A retrospective study 南印度地区护理医院新冠肺炎相关毛霉菌病的回顾性研究
Pub Date : 2023-04-01 DOI: 10.17727/jmsr.2023/11-29
Sahu S, P. P, Gafurjiwala Sm, Panigrahi M, Kumar Y, Nirupama Ay
{"title":"COVID-19 associated mucormycosis at territory care hospital in South India - A retrospective study","authors":"Sahu S, P. P, Gafurjiwala Sm, Panigrahi M, Kumar Y, Nirupama Ay","doi":"10.17727/jmsr.2023/11-29","DOIUrl":"https://doi.org/10.17727/jmsr.2023/11-29","url":null,"abstract":"","PeriodicalId":32890,"journal":{"name":"Journal of Medical and Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49343274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tibiotalocalcaneal arthrodesis with retrograde intramedullary nail for Charcot neuroarthropathy of foot - A prospective observational study 逆行髓内钉胫距跟骨关节融合术治疗足部Charcot神经关节病-一项前瞻性观察研究
Pub Date : 2023-04-01 DOI: 10.17727/jmsr.2023/11-25
Shanthi Ak, Binoy S, Biju S, Kumar Ka, Shibu R
Background: Surgical treatment is often needed for Charcot neuroarthropathy (CN) of foot. Even though good outcomes were reported with tibiotalocalcaneal arthrodesis (TTCA) in CN patients, the choice of implant is still an issue. The aim of the study was to evaluate the outcomes of TTCA with retrograde intramedullary nail, in patients with CN. Materials and methods: A prospective observational study was done with 41 consecutive patients treated with TTCA with hindfoot retrograde IM nail. The American Orthopaedic Foot and Ankle Society (AOFAS) score was used for the outcome evaluation, one year after surgery. Results: The mean age was 67.4(±8.7) years, with 63.5% females. Most common cause was diabetes mellitus (75.6%), followed by post-traumatic CN (19.5%) and chronic alcoholism (4.9%). Eleven (26.8%) had good score at the end of 1 year compared to five (12.2%) pre-op and twenty (48.8%) had fair score compared to fifteen (36.6%). The AOFAS score increased one year after surgery (p value 0.001). In twenty (48.8%) patients, the time taken for union was more than 6 months; and in 15 (36.6%) union occurred within 6 months of surgery. Six (14.6%) patients had non-union. Two (4.9%) had deep infection along with non-union. Hardware failure was seen in 3 (7.3%) patients. Hardware failure with non-union was reported in one (2.4%). Four (9.8%) patients had superficial wound infection and amputation done in one (2.4%) patient. Conclusion: Tibiotalocalcaneal arthrodesis with retrograde intramedullary nail is an acceptable and safe procedure with good clinical outcomes in patients with Charcot arthropathy which obviates the need for amputation. Keywords: Charcot neuroarthropathy; tibiotalocalcaneal arthrodesis; intramedullary nail; amputation
背景:足部Charcot神经关节病(CN)通常需要手术治疗。尽管有报道称CN患者采用胫距跟骨关节融合术(TTCA)获得了良好的疗效,但植入物的选择仍然是一个问题。本研究的目的是评价逆行髓内钉行TTCA治疗CN患者的疗效。材料和方法:对41例连续后足逆行内钉治疗TTCA的患者进行前瞻性观察研究。美国骨科足踝学会(AOFAS)评分用于手术后一年的结果评估。结果:平均年龄67.4(±8.7)岁,女性占63.5%。最常见的原因是糖尿病(75.6%),其次是创伤后CN(19.5%)和慢性酒精中毒(4.9%)。11例(26.8%)术后1年评分良好,术前5例(12.2%);20例(48.8%)术后评分一般,术前15例(36.6%)。术后1年AOFAS评分升高(p值0.001)。20例(48.8%)患者愈合时间超过6个月;15例(36.6%)术后6个月内愈合。6例(14.6%)患者出现骨不连。2例(4.9%)深度感染伴骨不连。3例(7.3%)患者出现硬件故障。1例(2.4%)报告了伴有骨不连的硬件故障。4例(9.8%)患者有浅表伤口感染,1例(2.4%)患者截肢。结论:逆行髓内钉胫距跟骨关节融合术是治疗Charcot关节病的一种安全可行的手术方法,临床疗效良好,无需截肢。关键词:Charcot神经关节病;tibiotalocalcaneal关节固定术;髓内钉;截肢
{"title":"Tibiotalocalcaneal arthrodesis with retrograde intramedullary nail for Charcot neuroarthropathy of foot - A prospective observational study","authors":"Shanthi Ak, Binoy S, Biju S, Kumar Ka, Shibu R","doi":"10.17727/jmsr.2023/11-25","DOIUrl":"https://doi.org/10.17727/jmsr.2023/11-25","url":null,"abstract":"Background: Surgical treatment is often needed for Charcot neuroarthropathy (CN) of foot. Even though good outcomes were reported with tibiotalocalcaneal arthrodesis (TTCA) in CN patients, the choice of implant is still an issue. The aim of the study was to evaluate the outcomes of TTCA with retrograde intramedullary nail, in patients with CN. Materials and methods: A prospective observational study was done with 41 consecutive patients treated with TTCA with hindfoot retrograde IM nail. The American Orthopaedic Foot and Ankle Society (AOFAS) score was used for the outcome evaluation, one year after surgery. Results: The mean age was 67.4(±8.7) years, with 63.5% females. Most common cause was diabetes mellitus (75.6%), followed by post-traumatic CN (19.5%) and chronic alcoholism (4.9%). Eleven (26.8%) had good score at the end of 1 year compared to five (12.2%) pre-op and twenty (48.8%) had fair score compared to fifteen (36.6%). The AOFAS score increased one year after surgery (p value 0.001). In twenty (48.8%) patients, the time taken for union was more than 6 months; and in 15 (36.6%) union occurred within 6 months of surgery. Six (14.6%) patients had non-union. Two (4.9%) had deep infection along with non-union. Hardware failure was seen in 3 (7.3%) patients. Hardware failure with non-union was reported in one (2.4%). Four (9.8%) patients had superficial wound infection and amputation done in one (2.4%) patient. Conclusion: Tibiotalocalcaneal arthrodesis with retrograde intramedullary nail is an acceptable and safe procedure with good clinical outcomes in patients with Charcot arthropathy which obviates the need for amputation. Keywords: Charcot neuroarthropathy; tibiotalocalcaneal arthrodesis; intramedullary nail; amputation","PeriodicalId":32890,"journal":{"name":"Journal of Medical and Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46232547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparison between ultrasound guided and landmark – based technique for superficial cervical plexus block in patients undergoing thyroid surgery 甲状腺手术患者颈浅丛阻滞的超声引导与标志性技术的比较
Pub Date : 2023-04-01 DOI: 10.17727/jmsr.2023/11-24
B. V, Saral Jn, K. M, Sureshbabu K, S. R.
Background: The major advantage of ultrasound guided technique over the traditional landmark technique in bilateral superficial cervical plexus block is that, it helps to minimize the injury to cervical muscle, fascia and nerves. The study aimed to compare the effectiveness between landmark technique and ultrasound guided technique with respect to the post-operative analgesia, intra-operative hemodynamics and the complication rate of the procedure. Methodology: A total of 100 patients were included as our study sample which was divided into two groups of 50 each. Group A patients received Superficial Cervical Plexus Block (SCPB) using the landmark based technique and Group B patients received SCPB under ultrasound guided technique. Parameters such as success of the procedure performance time, time of onset of action, block pain score, post-operative pain score, intra-operative hemodynamics and complication rate were compared between the two groups. Results: The success rate of the block was found to be 72% in the landmark technique group compared to 90% in the ultrasound guided group. The onsite time of analgesia was found to be much earlier in ultrasound guided group (16.2 vs 11.1 mins). The hemodynamic parameters were found to be slightly higher among the landmark group compared to ultrasound guided group. Post-operative pain score was significantly better and the incidence of complication rate was nil among ultrasound guided group. Conclusion: Ultrasound guided technique is a better alternate for landmark technique for providing bilateral superficial cervical plexus block while performing thyroidectomy surgery. Keywords: cervical plexus block; landmark technique; ultrasound technique; thyroidectomy
背景:与传统的标志性技术相比,超声引导技术在双侧颈浅丛阻滞中的主要优势在于,它有助于最大限度地减少对颈部肌肉、筋膜和神经的损伤。本研究旨在比较标志性技术和超声引导技术在术后镇痛、术中血液动力学和并发症发生率方面的有效性。方法:共有100名患者作为我们的研究样本,分为两组,每组50人。A组患者采用基于标志的技术进行颈浅丛阻滞(SCPB),B组患者采用超声引导技术进行SCPB。比较两组手术成功时间、起效时间、阻滞疼痛评分、术后疼痛评分、手术中血液动力学和并发症发生率等参数。结果:里程碑技术组的封堵成功率为72%,而超声引导组的成功率为90%。超声引导组的现场镇痛时间要早得多(16.2分钟vs 11.1分钟)。与超声引导组相比,里程碑组的血液动力学参数略高。超声引导组术后疼痛评分明显改善,并发症发生率为零。结论:超声引导技术是甲状腺手术中提供双侧颈浅丛阻滞的一种较好的替代标志性技术。关键词:颈丛阻滞;标志性技术;超声技术;甲状腺切除术
{"title":"Comparison between ultrasound guided and landmark – based technique for superficial cervical plexus block in patients undergoing thyroid surgery","authors":"B. V, Saral Jn, K. M, Sureshbabu K, S. R.","doi":"10.17727/jmsr.2023/11-24","DOIUrl":"https://doi.org/10.17727/jmsr.2023/11-24","url":null,"abstract":"Background: The major advantage of ultrasound guided technique over the traditional landmark technique in bilateral superficial cervical plexus block is that, it helps to minimize the injury to cervical muscle, fascia and nerves. The study aimed to compare the effectiveness between landmark technique and ultrasound guided technique with respect to the post-operative analgesia, intra-operative hemodynamics and the complication rate of the procedure. Methodology: A total of 100 patients were included as our study sample which was divided into two groups of 50 each. Group A patients received Superficial Cervical Plexus Block (SCPB) using the landmark based technique and Group B patients received SCPB under ultrasound guided technique. Parameters such as success of the procedure performance time, time of onset of action, block pain score, post-operative pain score, intra-operative hemodynamics and complication rate were compared between the two groups. Results: The success rate of the block was found to be 72% in the landmark technique group compared to 90% in the ultrasound guided group. The onsite time of analgesia was found to be much earlier in ultrasound guided group (16.2 vs 11.1 mins). The hemodynamic parameters were found to be slightly higher among the landmark group compared to ultrasound guided group. Post-operative pain score was significantly better and the incidence of complication rate was nil among ultrasound guided group. Conclusion: Ultrasound guided technique is a better alternate for landmark technique for providing bilateral superficial cervical plexus block while performing thyroidectomy surgery. Keywords: cervical plexus block; landmark technique; ultrasound technique; thyroidectomy","PeriodicalId":32890,"journal":{"name":"Journal of Medical and Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43213272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare association of brucellosis and pulmonary hydatid cyst in a patient with human immunodeficiency virus 人类免疫缺陷病毒患者布鲁氏菌病与肺棘球蚴囊肿的罕见关联
Pub Date : 2023-04-01 DOI: 10.17727/jmsr.2023/11-27
Kanugula S, Pasam Y, Baddula D
Background: Hydatid disease, or cystic echinococcosis, is a parasitic infection caused by a tapeworm. Pulmonary hydatid infection is the second common manifestation of hydatid disease. We present a patient who was diagnosed with recurrent hydatid cyst in lung and later diagnosed with brucellosis, which is a highly contagious zoonotic disease. Case presentation: A 47-years-old male was diagnosed with pulmonary hydatid disease after a computed tomography (CT) chest-plain was done. As the patient had high intermittent fever for 4 months which could not be explained by an intact cyst in the followup, the patient was diagnosed with brucellosis with both IgG and IgM antibodies positive. Conclusions: Hydatid cyst present with varied symptomatology. A high degree of clinical suspicion combined with meticulous history and clinical examination supported by laboratory investigations are required for its diagnosis. This case highlights the importance of considering brucella as a differential diagnosis. Keywords: hydatid cyst; brucellosis; co-infection; HIV; echinococcus
背景:棘球蚴病是由绦虫引起的寄生虫感染。肺棘球蚴感染是棘球蚴病的第二常见表现。我们介绍了一名患者,他被诊断为复发性肺棘球蚴病,后来被诊断为布鲁氏菌病,这是一种高度传染性的人畜共患疾病。病例介绍:一名47岁男性在做了计算机断层扫描(CT)胸部平片后被诊断为肺棘球蚴病。由于患者间歇性高烧达4个月,随访中无法用完整的囊肿来解释,患者被诊断为布鲁氏菌病,IgG和IgM抗体均呈阳性。结论:棘球蚴囊肿的症状多种多样。诊断它需要高度的临床怀疑,结合细致的病史和实验室调查支持的临床检查。该病例强调了将布鲁氏菌作为鉴别诊断的重要性。关键词:棘球蚴;布鲁氏菌病;共感染;艾滋病病毒;棘球蚴
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