Hamad S. Alyami, A. Naser, Mohammad H. Alyami, Ibraheem S. Banihameem, Mohammad Almusabi, A. Alqahtani, Mohammed A. Gannas, Hadi S Alyami, Hadi J. Al Sulayyim, Saeed F. Alkorbi, Hussain M. Alsagoor, A. Alyami, Rubiaan S. Almadi, S. Alharethi
There are limited studies in the Southern region of Saudi Arabia on the characteristics of hospitalised patients with cancer. The aim of this study was to explore the clinical and therapeutic characteristics of hospitalized cancer patients in the Najran Region of Saudi Arabia. A retrospective cross-sectional observational study was conducted using cancer patients’ medical records at the oncology unit in the King Khalid Hospital in Najran situated in the southern region of Saudi Arabia. Hospitalized patients’ records were extracted between 2014 and 2020. Logistic regression analysis was conducted to identify determinants of ICU admission among cancer patients. A total of 1,678 patients were involved in this study. The mean age was 52.5 (SD: 21.1) years. The average duration of stay was 8.7 days (SD: 13.4). The most commonly reported types of cancer were breast cancer, rectum cancer and colon cancer, accounting for 13.6%, 6.9%, and 6.7%, respectively. A total of 13.9% of the study participants required ICU admission. More than half (57.1%) of the patients were complaining of a moderate to severe case upon hospitalization. Older age (52.5 years and above) and the presence of comorbidities were risk factors that significantly increased the risk of ICU admission (P<.001). Patients with diabetes mellitus, hypertension, heart diseases, stroke, and kidney diseases were more likely to require ICU admissions. Patients with liver cancer were more likely to require ICU admission. Healthcare professionals should give extra care and health education for high risk cancer patients including elderly patients and those with other comorbidities to prevent complications and its associated hospitalization.
{"title":"Clinical and therapeutic characteristics of hospitalized cancer patients in the Najran Region of Saudi Arabia: a cross-sectional study","authors":"Hamad S. Alyami, A. Naser, Mohammad H. Alyami, Ibraheem S. Banihameem, Mohammad Almusabi, A. Alqahtani, Mohammed A. Gannas, Hadi S Alyami, Hadi J. Al Sulayyim, Saeed F. Alkorbi, Hussain M. Alsagoor, A. Alyami, Rubiaan S. Almadi, S. Alharethi","doi":"10.22146/jmpf.78654","DOIUrl":"https://doi.org/10.22146/jmpf.78654","url":null,"abstract":"There are limited studies in the Southern region of Saudi Arabia on the characteristics of hospitalised patients with cancer. The aim of this study was to explore the clinical and therapeutic characteristics of hospitalized cancer patients in the Najran Region of Saudi Arabia. A retrospective cross-sectional observational study was conducted using cancer patients’ medical records at the oncology unit in the King Khalid Hospital in Najran situated in the southern region of Saudi Arabia. Hospitalized patients’ records were extracted between 2014 and 2020. Logistic regression analysis was conducted to identify determinants of ICU admission among cancer patients. A total of 1,678 patients were involved in this study. The mean age was 52.5 (SD: 21.1) years. The average duration of stay was 8.7 days (SD: 13.4). The most commonly reported types of cancer were breast cancer, rectum cancer and colon cancer, accounting for 13.6%, 6.9%, and 6.7%, respectively. A total of 13.9% of the study participants required ICU admission. More than half (57.1%) of the patients were complaining of a moderate to severe case upon hospitalization. Older age (52.5 years and above) and the presence of comorbidities were risk factors that significantly increased the risk of ICU admission (P<.001). Patients with diabetes mellitus, hypertension, heart diseases, stroke, and kidney diseases were more likely to require ICU admissions. Patients with liver cancer were more likely to require ICU admission. Healthcare professionals should give extra care and health education for high risk cancer patients including elderly patients and those with other comorbidities to prevent complications and its associated hospitalization.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46935288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Knowledge of cardiovascular disease is essential for providing information about healthy behavior and to be proactive in reducing modifiable risk factors, control prevention, and improving early recognition. The existing study about knowledge of CVD in Indonesia is still limited. Hence, this study aimed to describe knowledge of CVD among general population in Indonesia and its association. A cross-sectional survey was conducted in 34 provinces in Indonesia from November-December 2021. Data were retrieved using a self-administered questionnaire. The Chi-Square analysis was performed to determine the association that contributes to overall knowledge of CVD. Among the 694 participants, 32.1% originated from Java, with the median age was 24 years and dominated by women (72.5%). The mean score of overall CVD knowledge was 59.6%, and only 39.1% of the participants had good knowledge of CVD. Cerebrovascular disease (94.7%) was the most identified various type of CVD. Likewise, unhealthy diet (77.2%), obesity (74.6%), and lack of exercise (72.5%) were the most identified risk factors. More than 50% of the participants recognized heart attack symptoms such as chest pain (77.1%) and shortness of breath (66.1%). Meanwhile, numbness or weakness (84.7%), trouble speaking (76.9%), and loss of balance (72.3%) were recognized as stroke symptoms. Gender, age, education level, working status, healthy food, smoking status, family history of CVD, ever checked blood pressure, fasting blood glucose, and total cholesterol were associated with overall knowledge of CVD. The disparity between level of CVD knowledge is not prominent among general population in Indonesia and further study need to establish.
{"title":"Knowledge of Cardiovascular Disease and its Association Among General Population in Indonesia","authors":"Bella Anggelina, S. A. Kristina, C. Wiedyaningsih","doi":"10.22146/jmpf.78070","DOIUrl":"https://doi.org/10.22146/jmpf.78070","url":null,"abstract":"Knowledge of cardiovascular disease is essential for providing information about healthy behavior and to be proactive in reducing modifiable risk factors, control prevention, and improving early recognition. The existing study about knowledge of CVD in Indonesia is still limited. Hence, this study aimed to describe knowledge of CVD among general population in Indonesia and its association. A cross-sectional survey was conducted in 34 provinces in Indonesia from November-December 2021. Data were retrieved using a self-administered questionnaire. The Chi-Square analysis was performed to determine the association that contributes to overall knowledge of CVD. Among the 694 participants, 32.1% originated from Java, with the median age was 24 years and dominated by women (72.5%). The mean score of overall CVD knowledge was 59.6%, and only 39.1% of the participants had good knowledge of CVD. Cerebrovascular disease (94.7%) was the most identified various type of CVD. Likewise, unhealthy diet (77.2%), obesity (74.6%), and lack of exercise (72.5%) were the most identified risk factors. More than 50% of the participants recognized heart attack symptoms such as chest pain (77.1%) and shortness of breath (66.1%). Meanwhile, numbness or weakness (84.7%), trouble speaking (76.9%), and loss of balance (72.3%) were recognized as stroke symptoms. Gender, age, education level, working status, healthy food, smoking status, family history of CVD, ever checked blood pressure, fasting blood glucose, and total cholesterol were associated with overall knowledge of CVD. The disparity between level of CVD knowledge is not prominent among general population in Indonesia and further study need to establish.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46199843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mera Putri Pratitis, Jason Merari Peranginangin, Ika Purwidyaningrum
The required elements in drug procurement are usage and drug requisition report or Laporan Pemakaian dan Lembar Permintaan Obat (LPLPO). The application of the Management Information System (MIS) at X Public Health Center cannot fulfill the function of preparing the LPLPO, so it has an impact on the planning and procurement of the drug. This study aims to evaluate and determine the design of MIS development of LPLPO at X Public Health Center, Surakarta City. The study is a qualitative descriptive study with inductive analysis. The sampling in this study is a purposive sampling. The sample in this study were officers who operated SIM both pharmacists and assistant pharmacists for at least 1 year. This research was conducted at X Public Health Center Surakarta City in September-October 2021. The design of the system in this study uses the prototype method based on the results of interviews. Interviews were conducted as an evaluation of MIS using the PIECES Framework method involving 4 informants. The license design is made using the context diagram and the flow diagram data (DFD). The results of the evaluation with the PIECES Framework show that the MIS that is applied can provide convenience for users in managing drug supplies even though it has not been optimized and has not met the needs so that the MIS is feasible to be developed. Based on the results of the evaluation, it can be concluded that the application of MIS can help and facilitate pharmacists in carrying out their work by providing accurate and complete data and information as supporting data for the preparation of LPLPO, but it cannot be used to monitor expired date of drug and prepare automatic LPLPO.
药品采购所需的要素是使用和药品申请报告或LPLPO (Laporan Pemakaian dan Lembar Permintaan Obat)。X公共卫生中心管理信息系统(MIS)的应用无法完成LPLPO的编制功能，影响了药品的规划和采购。本研究旨在评估并确定苏腊市X公共卫生中心LPLPO的MIS开发设计。本研究为定性描述性研究，并结合归纳分析。本研究的抽样是有目的抽样。本研究的样本为操作SIM的警官，包括药剂师和助理药剂师至少1年。这项研究于2021年9月至10月在泗水市X公共卫生中心进行。本研究的系统设计采用基于访谈结果的原型法。访谈是作为对管理信息系统的评估，使用了涉及4名举报人的PIECES框架方法。使用上下文图和流图数据(DFD)进行许可设计。使用PIECES框架进行评价的结果表明，所应用的管理信息系统虽然还没有得到优化和满足需求，但可以为用户管理药品供应提供便利，因此开发管理信息系统是可行的。根据评价结果，MIS的应用可以帮助和便利药师开展工作，为LPLPO的制备提供准确、完整的数据和信息作为支持数据，但不能用于监测药品的过期日期和自动制备LPLPO。
{"title":"Evaluasi Sistem Informasi Manajemen pada Laporan Pemakaian dan Lembar Permintaan Obat di Puskesmas X","authors":"Mera Putri Pratitis, Jason Merari Peranginangin, Ika Purwidyaningrum","doi":"10.22146/jmpf.76079","DOIUrl":"https://doi.org/10.22146/jmpf.76079","url":null,"abstract":"The required elements in drug procurement are usage and drug requisition report or Laporan Pemakaian dan Lembar Permintaan Obat (LPLPO). The application of the Management Information System (MIS) at X Public Health Center cannot fulfill the function of preparing the LPLPO, so it has an impact on the planning and procurement of the drug. This study aims to evaluate and determine the design of MIS development of LPLPO at X Public Health Center, Surakarta City. The study is a qualitative descriptive study with inductive analysis. The sampling in this study is a purposive sampling. The sample in this study were officers who operated SIM both pharmacists and assistant pharmacists for at least 1 year. This research was conducted at X Public Health Center Surakarta City in September-October 2021. The design of the system in this study uses the prototype method based on the results of interviews. Interviews were conducted as an evaluation of MIS using the PIECES Framework method involving 4 informants. The license design is made using the context diagram and the flow diagram data (DFD). The results of the evaluation with the PIECES Framework show that the MIS that is applied can provide convenience for users in managing drug supplies even though it has not been optimized and has not met the needs so that the MIS is feasible to be developed. Based on the results of the evaluation, it can be concluded that the application of MIS can help and facilitate pharmacists in carrying out their work by providing accurate and complete data and information as supporting data for the preparation of LPLPO, but it cannot be used to monitor expired date of drug and prepare automatic LPLPO.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48774705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Not all drugs side-effect that occur can be avoided, but those caused by drug-drug interactions (DDI) are among the most likely to be prevented and managed due to their predictability. The increasing number of drugs co-prescribed, affects the potential for drug interactions exponentially. Clinical Decision Support System (CDSS) is a promising strategy to prevent patient safety risks caused by drug interactions. This study aims to design a CDSS for DDI on e-Prescription. This research is qualitative study with action research design. The research was carried out at Digital Health Innovation Studio (DHIS) UGM, and at Budi Rahayu Hospital Magelang with the implementation time November 2021 - April 2022. Data collection for user needs analysis was carried out by interviewing management, doctors and pharmacists at the hospital, and also pharmacologists. Design and development of CDSS-DDI was executed in collaboration with DHIS UGM programmers. The evaluation was done by interviews and a System Usability Scale (SUS) questionnaire filled in by 17 system-related users. CDSS-DDI successfully developed according to user needs, it can be accessed by doctors and pharmacy units. The drug interaction warning display pop-up appears on one screen in the e-Prescription menu with a description of drug interactions in Bahasa. Drug interaction data refers to the National Drug Information Center (PIONas) which is managed by the POM. CDSS-DDI then implemented in hospital after going through socialization. Based on evaluation with SUS data processing tools, the CDSS-DDI received a score of 83 in the acceptable category and excellent rating. Based on results of evaluation interviews, CDSS for DDI is considered to have been successfully developed with the principle of user centered design and optimally efficient to help improve the quality of patient care.
{"title":"Perancangan Clinical Decision Support System (CDSS) untuk Drug Drug Interaction (DDI) pada e-Prescription","authors":"Resia Perwirani, Ika Puspitasari","doi":"10.22146/jmpf.74506","DOIUrl":"https://doi.org/10.22146/jmpf.74506","url":null,"abstract":"Not all drugs side-effect that occur can be avoided, but those caused by drug-drug interactions (DDI) are among the most likely to be prevented and managed due to their predictability. The increasing number of drugs co-prescribed, affects the potential for drug interactions exponentially. Clinical Decision Support System (CDSS) is a promising strategy to prevent patient safety risks caused by drug interactions. This study aims to design a CDSS for DDI on e-Prescription. This research is qualitative study with action research design. The research was carried out at Digital Health Innovation Studio (DHIS) UGM, and at Budi Rahayu Hospital Magelang with the implementation time November 2021 - April 2022. Data collection for user needs analysis was carried out by interviewing management, doctors and pharmacists at the hospital, and also pharmacologists. Design and development of CDSS-DDI was executed in collaboration with DHIS UGM programmers. The evaluation was done by interviews and a System Usability Scale (SUS) questionnaire filled in by 17 system-related users. CDSS-DDI successfully developed according to user needs, it can be accessed by doctors and pharmacy units. The drug interaction warning display pop-up appears on one screen in the e-Prescription menu with a description of drug interactions in Bahasa. Drug interaction data refers to the National Drug Information Center (PIONas) which is managed by the POM. CDSS-DDI then implemented in hospital after going through socialization. Based on evaluation with SUS data processing tools, the CDSS-DDI received a score of 83 in the acceptable category and excellent rating. Based on results of evaluation interviews, CDSS for DDI is considered to have been successfully developed with the principle of user centered design and optimally efficient to help improve the quality of patient care.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47065010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antiviral treatment for SARS-CoV2 (Severe Acute Respiratory Syndrome Coronavirus-2) is still being studied for its effectivity. The antivirals in the July 3, 2021 edition of the COVID-19 management guidelines, namely favipiravir and remdesivir, are used for moderate, severe and critical degrees. The study compares the mortality rate of COVID-19 patients taking the antivirals favipiravir and remdesivir. This research is a retrospective cohort study conducted at RSUP Dr. Sardjito Yogyakarta. The data was from the medical records of patients diagnosed with moderate, severe, and critical degrees of COVID-19 treated during the January-December 2021 period. Ninety-nine patients (50.8%) used favipiravir, while 97 patients (49.5%) used remdesivir. Chi-square analysis and multiple logistic regression were used to determine the relationship between research variables. Study subjects with the highest percentage of age 46-65 years (65%), male sex (54,6%), comorbid diabetes mellitus and hypertension (13,3%), severe degree of severity (60,7%), and viral load CT value ≤ 29 (80,1%), the patient went home alive (61,2%), and died (38,8%). The antivirals did not affect on mortality (p > 0,05). Further research is needed with the same characteristics of the two groups involving factors of degree severity of the disease, co-morbidity, and other medication therapy.
{"title":"Perbandingan Angka Kematian Terapi Antiviral Favipiravir dan Remdesivir pada Pasien COVID-19 Di RSUP Dr. Sardjito Yogyakarta","authors":"Nova Satriyani, Fita Rahmawati, T. Andayani","doi":"10.22146/jmpf.77288","DOIUrl":"https://doi.org/10.22146/jmpf.77288","url":null,"abstract":"Antiviral treatment for SARS-CoV2 (Severe Acute Respiratory Syndrome Coronavirus-2) is still being studied for its effectivity. The antivirals in the July 3, 2021 edition of the COVID-19 management guidelines, namely favipiravir and remdesivir, are used for moderate, severe and critical degrees. The study compares the mortality rate of COVID-19 patients taking the antivirals favipiravir and remdesivir. This research is a retrospective cohort study conducted at RSUP Dr. Sardjito Yogyakarta. The data was from the medical records of patients diagnosed with moderate, severe, and critical degrees of COVID-19 treated during the January-December 2021 period. Ninety-nine patients (50.8%) used favipiravir, while 97 patients (49.5%) used remdesivir. Chi-square analysis and multiple logistic regression were used to determine the relationship between research variables. Study subjects with the highest percentage of age 46-65 years (65%), male sex (54,6%), comorbid diabetes mellitus and hypertension (13,3%), severe degree of severity (60,7%), and viral load CT value ≤ 29 (80,1%), the patient went home alive (61,2%), and died (38,8%). The antivirals did not affect on mortality (p > 0,05). Further research is needed with the same characteristics of the two groups involving factors of degree severity of the disease, co-morbidity, and other medication therapy.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45974526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical Pharmacy Services (CPS) is provided by clinical pharmacists as members of the healthcare team. This is beneficial for hospital care. Therefore, knowing nurses' perception of CPS can determine the quality of healthcare provided and help in its improvement. This study aims to determine nurses' perception of clinical pharmacy services at the Universitas Sumatera Utara hospital, Medan, Indonesia. This is a descriptive study that used the Importance–Performance Analysis (IPA) method. The data were obtained by interviews and questionnaires to 60 nurses from October-December 2021. Five clinical pharmacy services are patient drug history, reconciliation, drug information services, recommendations and intervention in the integrated medical record, and sterile product dispensing. This study found that nurses have experienced the five clinical pharmacy services for as many as 52-60 people (87%-100%). Reconciliation, recommendations, and intervention in the integrated medical record are in Quadrant I. It shows that the performance of these services has not met the nurses' expectations. Drug information services are in Quadrant II. It shows that the service performance has been in line with the expectations. The patient's drug history is in Quadrant III. It shows low performance and is not expected by the nurse. The sterile product dispensing by clinical pharmacists is in quadrant IV. It shows that even though the perceived performance is good, the respondents do not consider this service to be important.
{"title":"Importance Performance Analysis Pelayanan Farmasi Klinik di RS Universitas Sumatera Utara dalam Persepsi Perawat","authors":"Rima Elfitra Rambe, K. Khairunnisa, W. Wiryanto","doi":"10.22146/jmpf.73842","DOIUrl":"https://doi.org/10.22146/jmpf.73842","url":null,"abstract":"Clinical Pharmacy Services (CPS) is provided by clinical pharmacists as members of the healthcare team. This is beneficial for hospital care. Therefore, knowing nurses' perception of CPS can determine the quality of healthcare provided and help in its improvement. This study aims to determine nurses' perception of clinical pharmacy services at the Universitas Sumatera Utara hospital, Medan, Indonesia. This is a descriptive study that used the Importance–Performance Analysis (IPA) method. The data were obtained by interviews and questionnaires to 60 nurses from October-December 2021. Five clinical pharmacy services are patient drug history, reconciliation, drug information services, recommendations and intervention in the integrated medical record, and sterile product dispensing. This study found that nurses have experienced the five clinical pharmacy services for as many as 52-60 people (87%-100%). Reconciliation, recommendations, and intervention in the integrated medical record are in Quadrant I. It shows that the performance of these services has not met the nurses' expectations. Drug information services are in Quadrant II. It shows that the service performance has been in line with the expectations. The patient's drug history is in Quadrant III. It shows low performance and is not expected by the nurse. The sterile product dispensing by clinical pharmacists is in quadrant IV. It shows that even though the perceived performance is good, the respondents do not consider this service to be important.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45533556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Nurhasnah, D. Viviandhari, R. N. Sakinah, Desi Wulandari
Drug information about Potentially Inappropriate Medications (PIMs) for elderly inpatients based on Beers 2019 is still limited in Indonesia. This study aimed to identify the incidence of PIMs using the 2019 Beers criteria in elderly patients and determine the factors associated with the incidence of PIMs. This research was observational with a cross-sectional approach. Data collection was carried out in the medical records section of a secondary referral hospital in Jakarta during August and September 2019. The number of samples was calculated using a sample size calculator, and data were obtained from the medical records of inpatients for the period January 2018-December 2018. The sampling of medical records was conducted with a non-probability sample with a purposive sampling technique. Inclusion criteria were medical records of inpatients aged 60 years or older. The exclusion criteria were patient medical records with incomplete data. The Beers 2019 criteria were used to identify PIMs. The results showed that from 325 medical records analyzed, PIMs were found in 122 (37.5%) elderly patients with a total incidence of 181 PIMs. Furosemide (25.4%) was the most common PIMs, followed by spironolactone (18.2%) and ranitidine (16%). The use of 10 medicines or more p<0.001, OR 4.26 95%CI (2.4-7.5) and a length of stay more than five days p=0.043 OR 1.65 95%CI (1.0- 2,6) was associated with a higher incidence of PIMs. However, age, gender, and the number of diagnoses were not significantly related to the incidence of PIMs. Health workers are advised to check serum creatinine in all hospitalized elderly patients and minimize the number of drugs used.
{"title":"Potentially Inappropriate Medication (PIMs) Identification Using 2019 Beers Criteria at a Secondary Referral Hospital in Jakarta","authors":"N. Nurhasnah, D. Viviandhari, R. N. Sakinah, Desi Wulandari","doi":"10.22146/jmpf.71246","DOIUrl":"https://doi.org/10.22146/jmpf.71246","url":null,"abstract":"Drug information about Potentially Inappropriate Medications (PIMs) for elderly inpatients based on Beers 2019 is still limited in Indonesia. This study aimed to identify the incidence of PIMs using the 2019 Beers criteria in elderly patients and determine the factors associated with the incidence of PIMs. This research was observational with a cross-sectional approach. Data collection was carried out in the medical records section of a secondary referral hospital in Jakarta during August and September 2019. The number of samples was calculated using a sample size calculator, and data were obtained from the medical records of inpatients for the period January 2018-December 2018. The sampling of medical records was conducted with a non-probability sample with a purposive sampling technique. Inclusion criteria were medical records of inpatients aged 60 years or older. The exclusion criteria were patient medical records with incomplete data. The Beers 2019 criteria were used to identify PIMs. The results showed that from 325 medical records analyzed, PIMs were found in 122 (37.5%) elderly patients with a total incidence of 181 PIMs. Furosemide (25.4%) was the most common PIMs, followed by spironolactone (18.2%) and ranitidine (16%). The use of 10 medicines or more p<0.001, OR 4.26 95%CI (2.4-7.5) and a length of stay more than five days p=0.043 OR 1.65 95%CI (1.0- 2,6) was associated with a higher incidence of PIMs. However, age, gender, and the number of diagnoses were not significantly related to the incidence of PIMs. Health workers are advised to check serum creatinine in all hospitalized elderly patients and minimize the number of drugs used.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41747505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eva Monica, K. R. Prilianti, Indah Lestari, Endhirayanti Caesarika
Health service facilities, especially pharmacies, play an important role in meeting the community's need for health support. A large number of pharmacies in Malang City and Regency is currently considered to be able to cause high competition between pharmacies so the geographic information system was chosen to see how the distribution of pharmacies is reviewed based on the population in each sub-district and the number of health facilities scattered in Malang. The purpose of this study was to determine the distribution pattern of pharmacies and their ratio to the total population density and health facilities in Malang City and Regency. The method used in this research is to collect data in the form of coordinate points of pharmacies and health facilities, followed by processing data in the form of a T index and using Arcgis 10.3 software to visualize it in the form of a map. In the analysis of the distribution of pharmacies in Malang City, the five sub-districts showed uniform or evenly distributed results, while in Malang District, out of 33 sub-districts, only 17 districts had a uniform pattern. Based on the ratio of pharmacies and the population of Kedungkandang District, it can be said to have the best accessibility, namely 1:1.010 (14:100,000), which has met the requirements set by the Ministry of Health and WHO. While the other 4 sub-districts in Malang City have met the requirements for pharmacists according to the Ministry of Health but have not met the requirements for pharmacists according to WHO. In Malang Regency, the standard of pharmacy service in terms of the ratio of the availability of pharmacies to the population has not been met, only 4 sub-districts have ratios that meet the requirements of the Ministry of Health but have not met the needs of WHO. The results of the ratio of pharmacies that were reviewed based on the number of health facilities showed that out of five sub-districts in Malang City, four other sub-districts namely Kedungkandang, Blimbing, Lowokwaru, and Klojen had a ratio with a good category, while Sukun District had a very good ratio. In Malang Regency, 17 sub-districts have a very good ratio, 3 sub-districts show a good ratio value, and 12 sub-districts have a ratio value of 0-0.9, indicating that the number of pharmacies in the sub-district is less than the number of health facilities.
{"title":"Pemanfaatan Sistem Informasi Geografis untuk Analisa Pola Distribusi Apotek di Kota dan Kabupaten Malang","authors":"Eva Monica, K. R. Prilianti, Indah Lestari, Endhirayanti Caesarika","doi":"10.22146/jmpf.67445","DOIUrl":"https://doi.org/10.22146/jmpf.67445","url":null,"abstract":"Health service facilities, especially pharmacies, play an important role in meeting the community's need for health support. A large number of pharmacies in Malang City and Regency is currently considered to be able to cause high competition between pharmacies so the geographic information system was chosen to see how the distribution of pharmacies is reviewed based on the population in each sub-district and the number of health facilities scattered in Malang. The purpose of this study was to determine the distribution pattern of pharmacies and their ratio to the total population density and health facilities in Malang City and Regency. The method used in this research is to collect data in the form of coordinate points of pharmacies and health facilities, followed by processing data in the form of a T index and using Arcgis 10.3 software to visualize it in the form of a map. In the analysis of the distribution of pharmacies in Malang City, the five sub-districts showed uniform or evenly distributed results, while in Malang District, out of 33 sub-districts, only 17 districts had a uniform pattern. Based on the ratio of pharmacies and the population of Kedungkandang District, it can be said to have the best accessibility, namely 1:1.010 (14:100,000), which has met the requirements set by the Ministry of Health and WHO. While the other 4 sub-districts in Malang City have met the requirements for pharmacists according to the Ministry of Health but have not met the requirements for pharmacists according to WHO. In Malang Regency, the standard of pharmacy service in terms of the ratio of the availability of pharmacies to the population has not been met, only 4 sub-districts have ratios that meet the requirements of the Ministry of Health but have not met the needs of WHO. The results of the ratio of pharmacies that were reviewed based on the number of health facilities showed that out of five sub-districts in Malang City, four other sub-districts namely Kedungkandang, Blimbing, Lowokwaru, and Klojen had a ratio with a good category, while Sukun District had a very good ratio. In Malang Regency, 17 sub-districts have a very good ratio, 3 sub-districts show a good ratio value, and 12 sub-districts have a ratio value of 0-0.9, indicating that the number of pharmacies in the sub-district is less than the number of health facilities.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68038967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atrial fibrillation can cause stroke due to blood stasis in the left atrium which triggers thrombus formation and embolization of the brain. Administration of anticoagulants is used to prevent clot formation to prevent the occurrence of stroke, but on the other hand, it is associated with the risk of bleeding side effects. This study aims to evaluate the safety of anticoagulants in ischemic stroke patients with atrial fibrillation. The study used a cross-sectional design. Retrospective data were taken from the medical records of RSUP Dr. Sardjito, Yogyakarta period January 2018 to December 2020. The research subjects were ischemic stroke patients with atrial fibrillation. Evaluation of the safety of anticoagulants includes the number of major and minor bleeding events in each type of anticoagulant and the factors that influence the occurrence of bleeding. A total of 70 patients met the study inclusion criteria. Bleeding occurred in 41 cases (58,57%). Major bleeding was 28 patients (40%) and minor bleeding was 13 patients (18,57%). The most common anticoagulant that causes bleeding is warfarin. Multivariate test of the factors that influence the occurrence of bleeding in kidney failure (OR = 5,990; 95% Cl 2,002-17,920; p = 0,001). Monitoring the side effects of anticoagulants, especially warfarin is necessary. Pharmacists can play an important role in monitoring and preventing bleeding events by taking into account risk factors, especially kidney failure.
{"title":"Keamanan Penggunaan Antiglukolan pada Pasien Rawat Inap Stroke Iskemik dengan Atrial Fibrilasi","authors":"Juniarto Mende, Fita Rahmawati, Ika Puspitasari","doi":"10.22146/jmpf.74893","DOIUrl":"https://doi.org/10.22146/jmpf.74893","url":null,"abstract":"Atrial fibrillation can cause stroke due to blood stasis in the left atrium which triggers thrombus formation and embolization of the brain. Administration of anticoagulants is used to prevent clot formation to prevent the occurrence of stroke, but on the other hand, it is associated with the risk of bleeding side effects. This study aims to evaluate the safety of anticoagulants in ischemic stroke patients with atrial fibrillation. The study used a cross-sectional design. Retrospective data were taken from the medical records of RSUP Dr. Sardjito, Yogyakarta period January 2018 to December 2020. The research subjects were ischemic stroke patients with atrial fibrillation. Evaluation of the safety of anticoagulants includes the number of major and minor bleeding events in each type of anticoagulant and the factors that influence the occurrence of bleeding. A total of 70 patients met the study inclusion criteria. Bleeding occurred in 41 cases (58,57%). Major bleeding was 28 patients (40%) and minor bleeding was 13 patients (18,57%). The most common anticoagulant that causes bleeding is warfarin. Multivariate test of the factors that influence the occurrence of bleeding in kidney failure (OR = 5,990; 95% Cl 2,002-17,920; p = 0,001). Monitoring the side effects of anticoagulants, especially warfarin is necessary. Pharmacists can play an important role in monitoring and preventing bleeding events by taking into account risk factors, especially kidney failure.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45413295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nurfina Dian Kartikawati, T. Andayani, Dwi Endarti
Chronic kidney disease (CKD) is a condition in which the kidneys are unable to maintain a fluid balance of metabolic waste that is progressive, irreversible, and takes place slowly. Anemia is a complication of CKD that contributes to morbidity, mortality, and quality of life of patients, as well as greater costs of care. This study aims to evaluate the differences in the effectiveness and cost of anemia therapy with epoetin in patients with chronic kidney disease. The study was conducted in an analytical-observational manner with a retrospective cohort design from the provider's perspective. The sample used was CKD patients with anemia who met the inclusion criteria for the period January - December 2020, data were taken from medical records and patient financial recapitulation. Statistical analysis was carried out on the effectiveness of anemia therapy with epoetin based on the achievement of clinical outcomes of increasing Hb values within 3 months and financing calculated based on direct medical costs. A total of 113 patients met the inclusion criteria, consisting of 96 patients in the epoetin alpha group and 17 patients in the epoetin beta group. The percentage of achieving therapeutic targets in the epoetin beta group was higher (11.76%) than in the epoetin alfa group (10.42%). The average increase in Hb in the EPO beta group was higher than in the EPO alpha group. The cost of epoetin for anemia treatment in the beta epoetin group (Rp 1,005,365) was lower than the epoetin alfa group (Rp 1,017,188). The ICER value obtained was IDR -125,966, indicating a cost savings of IDR 125,966 to increase 1% of the achievement of therapeutic targets for Hb values >10 g/dl. The cost of therapy with EPO beta is lower than EPO alpha and the achievement of Hb therapy targets is better in EPO beta than EPO alpha.
{"title":"Cost Effectiveness Analysis (CEA) Strategi Terapi Anemia pada Pasien Penyakit Ginjal Kronis","authors":"Nurfina Dian Kartikawati, T. Andayani, Dwi Endarti","doi":"10.22146/jmpf.72614","DOIUrl":"https://doi.org/10.22146/jmpf.72614","url":null,"abstract":"Chronic kidney disease (CKD) is a condition in which the kidneys are unable to maintain a fluid balance of metabolic waste that is progressive, irreversible, and takes place slowly. Anemia is a complication of CKD that contributes to morbidity, mortality, and quality of life of patients, as well as greater costs of care. This study aims to evaluate the differences in the effectiveness and cost of anemia therapy with epoetin in patients with chronic kidney disease. The study was conducted in an analytical-observational manner with a retrospective cohort design from the provider's perspective. The sample used was CKD patients with anemia who met the inclusion criteria for the period January - December 2020, data were taken from medical records and patient financial recapitulation. Statistical analysis was carried out on the effectiveness of anemia therapy with epoetin based on the achievement of clinical outcomes of increasing Hb values within 3 months and financing calculated based on direct medical costs. A total of 113 patients met the inclusion criteria, consisting of 96 patients in the epoetin alpha group and 17 patients in the epoetin beta group. The percentage of achieving therapeutic targets in the epoetin beta group was higher (11.76%) than in the epoetin alfa group (10.42%). The average increase in Hb in the EPO beta group was higher than in the EPO alpha group. The cost of epoetin for anemia treatment in the beta epoetin group (Rp 1,005,365) was lower than the epoetin alfa group (Rp 1,017,188). The ICER value obtained was IDR -125,966, indicating a cost savings of IDR 125,966 to increase 1% of the achievement of therapeutic targets for Hb values >10 g/dl. The cost of therapy with EPO beta is lower than EPO alpha and the achievement of Hb therapy targets is better in EPO beta than EPO alpha.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42731914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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