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Androgen insensitivity syndrome in an Indian adult 印度成人雄激素不敏感综合征
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.108135
T. Borah, R. K. Mahanta
In androgen insensitivity syndrome (AIS), the patients are phenotypically females with male karyotype. Affected persons present at puberty with primary amenorrhea with adequate breast development and normal external genitalia. The gonads may be found in lower abdomen, inguinal regions, or sometimes in the labia majora. Rarely, the testes may undergo malignant transformation. So, gonadectomy is indicated in these patients after they attain puberty. Here, we present a case of AIS with primary amenorrhea and bilateral inguinal swelling.
在雄激素不敏感综合征(AIS)中,患者表现为男性核型的女性。受影响的人在青春期出现原发性闭经,乳房发育正常,外生殖器正常。性腺可见于下腹部、腹股沟区,有时也见于大阴唇。极少数情况下,睾丸可能发生恶性转化。因此,性腺切除术是在这些患者进入青春期后进行的。在此,我们报告一原发性闭经及双侧腹股沟肿胀的AIS病例。
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引用次数: 0
An unusual reaction to ketamine in a child 儿童对氯胺酮的不寻常反应
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.73880
E. Nwasor, P. Mshelbwala
Ketamine, a phencyclidine derivative, is a very popular and commonly used parenteral anesthetic agent. It is a safe drug in unskilled hands and a drug of choice in high-risk patients. We report an unusual allergic reaction to Ketamine in a 2.5-year-old child with bilateral congenital inguinal hernia. This is to alert all practitioners to some of the rare but potentially fatal side effects of Ketamine. Anaphylactic reactions to Ketamine are a rare but potentially fatal occurrence. Management includes treatment of acute reactions and avoidance of future reactions. There is no known antidote or reversal agent to Ketamine. So, once it is administered, one must be ready for it to complete full duration of its action. Facilities for resuscitation must be available any time an anesthetic is being administered, no matter how short or minor the surgery is.
氯胺酮是一种苯环利定的衍生物,是一种非常流行和常用的肠外麻醉剂。对于不熟练的人来说,它是一种安全的药物,也是高危患者的首选药物。我们报告一个不寻常的过敏反应氯胺酮在一个2.5岁的儿童与双侧先天性腹股沟疝。这是为了提醒所有从业者注意氯胺酮的一些罕见但可能致命的副作用。对氯胺酮的过敏反应是一种罕见但可能致命的事件。管理包括治疗急性反应和避免未来的反应。氯胺酮没有已知的解毒剂或逆转剂。因此,一旦给药,必须准备好让它完全发挥作用。在麻醉过程中,无论手术时间有多短或多小,都必须有复苏设备。
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引用次数: 7
Mooren′s corneal ulceration in a pseudophakic eye: A case report and literature review 假性失视眼Mooren角膜溃疡1例报告并文献复习
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.100229
Er Abah, A. Akinwande, V. Pam
Surgery (ECCE+ PCIOL) is an unusual possible aetiology of Mooren′s corneal ulceration. A clinical and laboratory evaluation of a case of a 60-year-old male Nigerian who in the immediate postoperative period developed Mooren′s corneal ulceration after an uneventful extracapsular cataract extraction and a posterior chamber intraocular lens (ECCE+PCIOL) implantation at an outreach center is presented. Healing occurred within 2 weeks of medical and surgical intervention, but no remarkable visual improvement. A review of literature from relevant sources with emphasis on management options is also incorporated. Many cases of Mooren′s corneal ulceration remain refractory to treatment even in advanced countries. However, early case finding and prompt referral by trained primary eye care personnel may help to reduce severe visual morbidity in this environment.
手术(ECCE+ PCIOL)是莫伦氏角膜溃疡的一种不寻常的可能病因。本文介绍了一名60岁尼日利亚男性患者的临床和实验室评估,该患者在外展中心进行白内障囊外摘除术和后房型人工晶状体(ECCE+PCIOL)植入术后,术后立即发生Mooren角膜溃疡。治疗在2周内发生,但没有明显的视力改善。从相关来源的文献审查,重点是管理选择也纳入。即使在发达国家,许多莫伦氏角膜溃疡病例仍然难以治疗。然而,早期发现病例并由训练有素的初级眼科保健人员及时转诊可能有助于减少这种环境下严重的视力发病率。
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引用次数: 1
Benign breast diseases in Warri Southern Nigeria: A spectrum of histopathological analysis 尼日利亚南部瓦里的良性乳腺疾病:组织病理学分析的频谱
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.141026
G. Forae, F. Nwachokor, A. Igbe, E. Odokuma, E. Ijomone
Background: Benign breast diseases (BBDs) constitute a source of morbidity and mortality among women globally. Most of these lesions are common in women of reproductive age and are associated with hormonal influences. However, studies have reported an increasing incidence of these lesions in children and adolescents. Aims: The aim was to highlight the spectrum and histological patterns of BBDs among women in Delta State and other Southern states of Nigeria as seen at central hospital, Warri. Materials and Methods: This study was a 7-year retrospective analysis of all histologically diagnosed breast diseases in women. Request forms were scrutinized for clinical bio-data, diagnosis. Hematoxylin and eosin stained-slides of breast biopsies carried out at the central hospital, Warri were archived and studied. Results: A total of 905 breast lesions were received during this 7 years period in the Pathology Department. Of these, 644 cases accounting for (71.2%) were benign lesions, while 261 cases (28.8%) were malignant giving a ratio of 2.5:1. A total of 638 cases occurred in female while only 6 cases occurred in males. The mean age was 31.2 ± 8.4 years, and the peak age incidence was 20-29 years constituting 49.8% cases of BBDs. Fibroadenoma was the most common BBD accounting for 302 cases (46.9%). Fibrocystic disease was the second majority and constituted 126 cases (19.6%). Conclusion: Fibroadenoma constituted the most common histopathological patterns of BBDs in children and adolescents in our environment.
背景:乳腺良性疾病(BBDs)是全球妇女发病率和死亡率的来源之一。大多数这些病变常见于育龄妇女,并与激素的影响有关。然而,研究报告这些病变在儿童和青少年中的发病率越来越高。目的:目的是强调在瓦里中心医院看到的三角洲州和尼日利亚其他南部州的妇女中bbd的频谱和组织学模式。材料和方法:本研究对所有经组织学诊断的女性乳腺疾病进行了7年的回顾性分析。申请表被仔细审查临床生物数据,诊断。在Warri中心医院进行的乳房活检的苏木精和伊红染色切片被存档和研究。结果:病理科7年间共接收乳腺病变905例。其中良性病变644例(71.2%),恶性病变261例(28.8%),两者之比为2.5:1。女性638例,男性6例。平均年龄为31.2±8.4岁,发病高峰年龄为20 ~ 29岁,占bbd病例的49.8%。纤维腺瘤是最常见的BBD,占302例(46.9%)。纤维囊性疾病次之,126例(19.6%)。结论:纤维腺瘤构成了我们环境中儿童和青少年bbd最常见的组织病理学模式。
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引用次数: 20
Treatment of constipation in children based on anorectal manometery findings 基于肛门直肠测压结果的儿童便秘治疗
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.100205
S. Hosseini, M. Zarenezhad, A. Hedjazi, M. Khazdooz, S. Falahi
Background: Constipation is a common symptom in children and manometery can be a useful diagnostic method in choosing suitable therapeutic methods for these patients. Aim: The aim of this study was to assess the manometeric findings and determine its role in the management of children with constipation referred to our hospital. Setting and Design: This was a descriptive cross-sectional study. Materials and Methods : It was carried out on patients referred from September 2006 to December 2009 to the children hospital for performance of anorectal manometery because of constipation. They received their treatment according to findings at manometry (normal, absent, dilated, and retentive) with Botolinium toxin (BT) injection, surgery, enema, and medications, respectively. For each patient, variables such as age, sex, chief complaint, manometry result, food regimen, and treatment method were recorded. Symptom severity scale was assessed using a scored questionnaire. Statistical Analysis: Data were analyzed using SPSS 17 and descriptive statistics, t-test, and χ2 . Results: Seventy-one patients were included in our study. The mean age of the participants was 4.98 ΁ 1.43. Sixteen (22.5%) had acute and 55 (77.5%) had chronic constipation. Seventeen (25.4%) had a diagnosis of Hirschsprung′s disease and 22 patients (31%) had retentive type constipation. Nineteen patients (28.8%) received pull through treatment and 27 (38%) received BT, while 34 (47.9%) received medical treatment. Mean symptom severity score after treatment was 3.88 and 4.59 in males and females, respectively. This difference was statistically significant (P = 0.03). There was no statistically significant difference after treatment according to other variables. Conclusions : In summary, our study results were comparable with studies that reported an effective role for manometry in diagnosis and planning the type of treatment in constipated children. and is a useful physiologic tool for measuring anorectal complex function.
背景:儿童便秘是一种常见的症状,测压是一种有用的诊断方法,可以为这些患者选择合适的治疗方法。目的:本研究的目的是评估测压结果,并确定其在处理儿童便秘转介到我院。环境与设计:这是一项描述性横断面研究。材料与方法:对2006年9月至2009年12月儿童医院因便秘行肛肠测压术的患者进行研究。根据测压结果(正常、缺失、扩张和保留)分别给予肉毒杆菌毒素(BT)注射、手术、灌肠和药物治疗。记录每位患者的年龄、性别、主诉、测压结果、饮食方案和治疗方法等变量。使用计分问卷对症状严重程度量表进行评估。统计分析:采用SPSS 17、描述性统计、t检验、χ2对数据进行分析。结果:71例患者纳入我们的研究。参与者的平均年龄为4.98岁或1.43岁。急性便秘16例(22.5%),慢性便秘55例(77.5%)。17例(25.4%)被诊断为先天性巨结肠病,22例(31%)被诊断为滞留型便秘。接受拉通治疗19例(28.8%),BT治疗27例(38%),内科治疗34例(47.9%)。治疗后男性和女性的平均症状严重程度评分分别为3.88和4.59。差异有统计学意义(P = 0.03)。其他变量处理后差异无统计学意义。结论:总之,我们的研究结果与报道血压测量在便秘儿童诊断和计划治疗类型中的有效作用的研究相当。是测量肛肠复合体功能的一种有用的生理工具。
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引用次数: 3
Child sexual abuse: A review of cases seen at General Hospital Suleja, Niger State 儿童性虐待:对尼日尔州苏莱贾总医院病例的审查
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.84223
I. Abdulkadir, L. Umar, H. Musa, S. Musa, Olusegun Abegunde Oyeniyi, Oluwaseyi Ayoola-Williams, Ladi Okeniyi
Background : Sexual abuse of children is a global health and human rights problem that has been largely underreported and understudied in sub-Saharan Africa. Little is therefore known regarding information on the nature of child sexual abuse and the predisposing factors in our communities. Objective : To study the demographic features of individuals involved in sexual abuse and the pattern of presentation of cases at the General Hospital Suleja, Niger state. Materials and Methods : The study is a retrospective analysis of case records of patients who presented to the Out Patient Department of General Hospital Suleja. All cases of sexual abuse seen over an 18 month period from 1 st January 2007 to 30 th June 2008 were reviewed. Data obtained were analysed in Epi-Info software version 3.04 and results presented as percentages, contingency tables, and charts. Results : A total of 81 cases of sexual abuse were recorded over the period of review where children (77 cases) accounted for 95.1% of the cases. There were 41 cases of sexual abuse seen in 2007, while 40 cases were documented within the first half of 2008. All the victims of sexual abuse were girls and all the perpetrators were males of whom six adolescent boys constituted 7.6%. There was no documentation on evaluation and management of sexually transmitted infections, HIV infection, emergency contraception, or scheduled follow-up. Conclusion : The incidence of reported child sexual abuse is on the increase in our communities. There is a need for studies on the predisposing factors to inform policy and preventive strategies as well as efforts to build the capacity of public health systems and care providers to manage cases reporting to our health care facilities.
背景:对儿童的性虐待是一个全球性的健康和人权问题,但在撒哈拉以南非洲,对这一问题的报道和研究大都不足。因此,关于我们社区中儿童性虐待的性质和诱发因素的信息所知甚少。目的:研究尼日尔州苏莱贾总医院涉及性虐待的个人的人口统计学特征和病例呈现模式。材料与方法:本研究回顾性分析苏雷加综合医院门诊部收治的病例记录。从2007年1月1日至2008年6月30日18个月期间发生的所有性虐待案件都进行了审查。采用Epi-Info 3.04版软件对所得数据进行分析,结果以百分比、列联表和图表形式呈现。结果:回顾期内共记录性侵案件81起,其中儿童77起,占95.1%。2007年有41起性虐待案件,而2008年上半年有40起案件被记录在案。所有性虐待的受害者都是女孩,所有施暴者都是男性,其中6名青春期男孩占7.6%。没有关于性传播感染、艾滋病毒感染、紧急避孕或预定随访的评估和管理的文件。结论:在我们的社区中,儿童性虐待报告的发生率正在上升。有必要研究易感因素,为政策和预防策略提供信息,并努力建立公共卫生系统和护理提供者的能力,以管理向我们的卫生保健设施报告的病例。
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引用次数: 23
Foramen magnum syndrome from a tumor in a neurofibromatosis type 1 patient 1型神经纤维瘤病患者肿瘤所致的枕骨大孔综合征
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.141029
L. Owolabi, H. Mohammed, I. Alhaji
Foramen magnum tumors are rare in neurofibromatosis type 1. They may present with bizarre symptoms and may mimic many neurological conditions. We report a case of foramen magnum syndrome secondary to tumor misdiagnosed as cervical spine tuberculosis.
枕骨大孔肿瘤在1型神经纤维瘤病中是罕见的。他们可能会表现出奇怪的症状,并可能模仿许多神经系统疾病。我们报告一例大孔综合征继发于肿瘤误诊为颈椎结核。
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引用次数: 0
Knowledge, attitude, and practice of basic hospital management principles among medical doctors in Lokoja, Nigeria 尼日利亚洛科贾医生对医院基本管理原则的认识、态度和实践
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.163326
Ohireimen Ohioze, B. James
Background: Good management skills are required by medical doctors to offer optimal service to clients (patients). Though doctors are often managers, basic hospital management principles are lacking in the training curriculum, and may affect how they organize multi-disciplinary teams or units in synergizing healthcare delivery. Aims: This study sought to determine the level of knowledge, attitude, and practice of management principles among private and public medical doctors in Lokoja. Materials and Methods: A cross-sectional study of 160 medical doctors using a pretested 23-item closed-ended questionnaire. Descriptive and bivariate analyses (using the Chi-squared, Pearson′s correlations and Students′ t-tests) were performed to compare categorical and continuous outcomes respectively. Results: A total of 70.9% of respondents were found to have a high knowledge of basic management principles, 80.6% had a positive attitude toward management principles while only 35.6% of respondents actually used formal management principles in their administrative work. Public sector doctors had significantly better knowledge (P < 0.001), positive attitudes (P < 0.003), and higher level of practice (P < 0.004) compared to private sector doctors. There was a positive linear relationship among knowledge and attitude (R = 0.47), knowledge and practice (R = 0.33), and attitude and practice (R = 0.38). Conclusion: Public sector doctors had higher knowledge and better attitudes toward management principles compared to private sector colleagues. Low levels of practice of basic management principles were seen in both groups. This study sets the groundwork for future research.
背景:良好的管理技能是医生为客户(病人)提供最佳服务所必需的。虽然医生往往是管理者,但在培训课程中缺乏基本的医院管理原则,这可能会影响他们如何组织多学科团队或单位协同医疗服务。目的:本研究旨在确定Lokoja私立和公立医生对管理原则的知识、态度和实践水平。材料与方法:采用23项封闭式问卷预测法对160名医生进行横断面研究。分别进行描述性和双变量分析(使用卡方、Pearson相关和学生t检验)来比较分类和连续结果。结果:70.9%的受访者对基本管理原则有较高的认识,80.6%的受访者对管理原则持积极态度,而在行政工作中实际使用正式管理原则的受访者仅占35.6%。公立医院医生的知识水平(P < 0.001)、积极态度(P < 0.003)和执业水平(P < 0.004)均显著高于私立医院医生。知识与态度(R = 0.47)、知识与实践(R = 0.33)、态度与实践(R = 0.38)呈线性正相关。结论:与私营部门相比,公立部门医生对管理原则的了解程度更高,态度也更好。两组患者对基本管理原则的实践水平均较低。本研究为今后的研究奠定了基础。
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引用次数: 3
Pattern of adipose tissue tumors in Ahmadu Bello Universty Teaching Hospital, Zaria, Nigeria 尼日利亚扎里亚Ahmadu Bello大学教学医院脂肪组织肿瘤的模式
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.141022
U. Mohammed, M. Samaila, M. Abubakar
Background: Adipose tumors are the most common soft tissue tumors in humans. The reported incidence of lipoma is probably less than the actual incidence because of its insidious growth pattern and minimal associated symptoms. Objective: The objective of this study is to document the pattern of these tumors in a tertiary hospital in Northern Nigeria. Materials and Method: This is a retrospective study of all diagnosed adipose tissue tumor over a 10-year period (January 2002 to December 2011), in the Department of Pathology, Ahmadu Bello University Teaching Hospital. Tissue biopsies fixed in 10% formalin and stained routinely with hematoxylin and eosin were studied. Biodata and sites of involvement were retrieved from patients′ requisition cards. Results: Four hundred and three adipose tissue tumors were diagnosed during this period. Three hundred and ninety-five (98.0%) of the tumors were benign, while 8 (2.0%) were malignant. The male to female distribution was 197 and 206, respectively. Patients ages ranged from 3 months to 75 years with a peak age distribution in the fifth decade (23.6%). The most common site of involvement was the trunk (38.0%), followed by the head and neck region (21.3%) and lower limbs (17.4%). Conventional lipoma was the most common benign tumor, accounting for 328 cases (81.4%), while myxoid liposarcoma was the most common malignant tumor with 4 cases (1.0%). Conclusion: Adipose tissue tumors are not uncommon in our setting and accounted for 6.0% of all tumors seen within the study period. There is a slight female preponderance and the trunk is the most common site of involvement. Benign tumors formed the bulk of lesions recorded.
背景:脂肪肿瘤是人类最常见的软组织肿瘤。由于脂肪瘤的生长方式隐匿且相关症状极少,因此报告的发病率可能低于实际发病率。目的:本研究的目的是记录这些肿瘤在尼日利亚北部三级医院的模式。材料和方法:本研究是对Ahmadu Bello大学教学医院病理学系10年间(2002年1月至2011年12月)所有诊断为脂肪组织肿瘤的回顾性研究。组织活检用10%福尔马林固定,苏木精和伊红常规染色。从患者的申请卡中检索生物数据和涉及部位。结果:本研究共发现脂肪组织肿瘤403例。良性肿瘤395例(98.0%),恶性肿瘤8例(2.0%)。男女分布分别为197只和206只。患者年龄从3个月到75岁不等,年龄分布高峰在第5个10年(23.6%)。最常见的受累部位是躯干(38.0%),其次是头颈部(21.3%)和下肢(17.4%)。常规脂肪瘤为最常见的良性肿瘤,共328例(81.4%);黏液样脂肪肉瘤为最常见的恶性肿瘤,共4例(1.0%)。结论:脂肪组织肿瘤在我们的研究中并不罕见,占研究期间所有肿瘤的6.0%。有轻微的女性优势,躯干是最常见的受累部位。记录的病变中大部分为良性肿瘤。
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引用次数: 3
Cytodiagnosis of microfilarial lymphadenitis coexistent with metastatic squamous cell carcinoma in a left cervical lymph node: An unusual presentation 左颈淋巴结微丝性淋巴结炎合并转移性鳞状细胞癌的细胞诊断:一种不寻常的表现
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.100228
T. Katti, Vidhisha S Athanikar, Anand S Ananthrao, Chandrakanth V Rathod
Filariasis is one of the parasitic diseases endemic in India, manifesting as acute, chronic or asymptomatic disease. Wuchereria bancrofti accounts for 90% of cases. Microfilaria in fine-needle aspiration cytology is not a common finding. It has been occasionally detected in association with neoplasms. Coexistence with metastatic deposits is even rarer on cytology. We found it incidentally in metastasis to cervical lymph node from squamous cell carcinoma growing in the middle third of the esophagus on fine-needle aspiration (FNA). This patient presented with left-sided neck swelling for 2 months and complete hemogram and peripheral blood smear were normal. We report this case for the rarity of pathology.
丝虫病是印度地方性寄生虫病之一,表现为急性、慢性或无症状疾病。班氏杆菌占90%的病例。微丝蚴在细针穿刺细胞学检查中并不常见。它偶尔也被发现与肿瘤有关。与转移性沉积共存在细胞学上更为罕见。我们在细针穿刺(FNA)中发现它偶然发生在食管中部三分之一的鳞状细胞癌转移到颈部淋巴结。患者左侧颈部肿胀2个月,全血象和外周血涂片正常。我们报告这个病例的罕见病理。
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引用次数: 8
期刊
Annals of Nigerian Medicine
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