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A 17-year-old of Nigerian girl with Sydenham chorea: A case report and review of literature 17岁尼日利亚女童西德纳姆舞蹈病1例报告及文献复习
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.163332
E. Ezunu, C. Njoku
This is a 17-year-old Nigerian girl who had a history of a sore throat for 8 weeks and persistent fever, associated with central chest pain, abnormal fidgety movement of the body and fleeting joint pain. The diagnosis of Sydenham chorea was made due to the additional finding of positive anti-streptolysin O titer. Sydenham chorea is a neuropsychiatric disorder that is characterized by abnormal body movement, associated with mood and behavioral changes. It is an autoimmune disease that occurs following an infection with M serotype of Group A beta-hemolytic streptococcal infection that is prevalent in our environment. However, Sydenham chorea which is one of its manifestations is still rare in our environment, hence the need for literature review.
这是一名17岁的尼日利亚女孩,有8周的喉咙痛史和持续发热,伴有中枢性胸痛、身体异常烦躁运动和短暂的关节疼痛。Sydenham舞蹈病的诊断是由于抗溶血素O滴度阳性的额外发现。西德纳姆舞蹈病是一种神经精神疾病,其特征是异常的身体运动,与情绪和行为变化有关。这是一种自身免疫性疾病,发生在感染M血清型A群-溶血性链球菌感染后,在我们的环境中很普遍。然而,作为其表现之一的Sydenham舞蹈病在我们的环境中仍然很少见,因此需要进行文献综述。
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引用次数: 0
Tuberculosis-associated immune reconstitution inflammatory syndrome: Management challenges in resource-limited settings 结核病相关免疫重建炎症综合征:资源有限环境下的管理挑战
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.100196
Mukhtar Abdulmajid Adeiza
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引用次数: 0
Lipid abnormalities: A case study of Ahmadu Bello University Teaching Hospital, Zaria, Nigeria 脂质异常:以尼日利亚扎里亚Ahmadu Bello大学教学医院为例
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.73869
S. Akuyam, P. Anaja, H. Isah, I. Aliyu, R. Yusuf
Background : Abnormal lipid levels, especially elevated total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and triglyceride (TG) and decreased high density lipoprotein cholesterol (HDL-C), contribute additional risk to patients with diabetes mellitus (DM) and coronary heart disease (CHD). Reports on the pattern of lipid profile abnormality in blacks are scanty and inconsistent. The aim of the present study has been to carry out a retrospective analysis of lipid profile investigation in Ahmadu Bello University Teaching Hospital (ABUTH), Zaria. Materials and Methods : A total of 448 patients with different disease conditions, such as type II DM, CHD, renal disorders, liver diseases and other abnormalities, who were referred to the chemical pathology laboratory from various clinics and hospitals for lipid profile analysis were assessed. The subjects were made up of 312 (69.67%) males and 136 (30.33%) females. The mean age for the total (combined males and females) was 58 (ranged 45-72) years and the mean age values for males and females were 62 (ranged 51-73) and 53 (ranged 35-65) years respectively. Results : The results show that abnormal lipid profile was found in 51 (11.38%) patients who were consisted of 33 (67.71%) males and 18 (35.29%) females. These also consisted of 35 (68.63%) patients with cardiovascular diseases (CVD), 5 (9.80%) patients with type II diabetes mellitus (DM) and 11 (21.57%) patients with other clinical conditions such as liver and renal diseases. Hypercholesterolemia and hypertriglyceridemia alone were observed in 8 and 15 patients respectively. Low density lipoprotein cholesterol (LDL-C) levels were elevated in 11 patients. Thirty six (36) patients had reduced levels of HDL-C only, with concomitant high levels of TC/HDL-C ratio. Combined hyperlipidemia was observed in only five patients. The results revealed that abnormal lipid profile pattern was higher in patients with CVD (68.60%) than in other cases. Conclusion : The results of the present study demonstrate that low HDL-C levels seemed to be more prevalent in this population. This report could contribute to the ongoing work on lipid research in Nigeria and the world at large.
背景:血脂水平异常,特别是总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和甘油三酯(TG)升高以及高密度脂蛋白胆固醇(HDL-C)降低,是糖尿病(DM)和冠心病(CHD)患者的额外危险因素。关于黑人血脂异常模式的报道很少,也不一致。本研究的目的是对扎里亚Ahmadu Bello大学教学医院(ABUTH)的血脂调查进行回顾性分析。材料与方法:对各诊所、医院转至化学病理实验室进行血脂分析的不同疾病情况(如II型糖尿病、冠心病、肾脏疾病、肝脏疾病及其他异常)患者448例进行评估。其中男性312人(69.67%),女性136人(30.33%)。患者男女合计平均年龄为58岁(45 ~ 72岁),男女平均年龄分别为62岁(51 ~ 73岁)和53岁(35 ~ 65岁)。结果:51例(11.38%)患者出现血脂异常,其中男性33例(67.71%),女性18例(35.29%)。其中心血管疾病(CVD)患者35例(68.63%),II型糖尿病(DM)患者5例(9.80%),其他临床疾病(如肝肾疾病)患者11例(21.57%)。单独出现高胆固醇血症和高甘油三酯血症分别为8例和15例。11例患者低密度脂蛋白胆固醇(LDL-C)水平升高。36例患者仅HDL-C水平降低,同时TC/HDL-C比值升高。合并高脂血症仅5例。结果显示,CVD患者的血脂异常模式高于其他病例(68.60%)。结论:本研究的结果表明,低HDL-C水平似乎在这一人群中更为普遍。本报告可为尼日利亚和全世界正在进行的脂质研究工作作出贡献。
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引用次数: 4
Familial renal tubular acidosis: Report of two cases from a single family 家族性肾小管性酸中毒:一家族二例报告
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.163334
Alina Naeem, M. Kiblawi, Subhranshu Sekhar Kar, E. Ahmed, S. Mossad, B. Manjunatha Goud
Renal tubular acidosis (RTA) is a disease that occurs when the kidneys fail to excrete acids into the urine, as a result of which the person′s blood remains very acidic. Without proper treatment, chronic acidity of the blood leads to chronic kidney disease, kidney stones, metabolic bone disease, and growth failure. These are relatively rare inherited renal tubular disorders. We report two cases from a single family with distal RTA (dRTA) or Type 1 RTA presenting with varied clinical manifestations. Sensorineural deafness, which is rarely associated with dRTA, was present in the elder sibling.
肾小管酸中毒(RTA)是一种肾脏不能将酸排泄到尿液中的疾病,其结果是人的血液仍然呈酸性。如果没有适当的治疗,慢性血液酸性会导致慢性肾脏疾病、肾结石、代谢性骨病和生长衰竭。这些是相对罕见的遗传性肾小管疾病。我们报告两例来自同一家族的远端RTA (dRTA)或1型RTA,其临床表现各不相同。感觉神经性耳聋,很少与dRTA相关,出现在哥哥姐妹中。
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引用次数: 2
Prevalence of malaria among HIV patients on highly active antiretroviral therapy in Kogi State, North Central Nigeria 尼日利亚中北部科吉州接受高效抗逆转录病毒治疗的艾滋病毒患者中疟疾流行情况
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.189802
F. Akinbo, Peter Joel Anate, D. Akinbo, R. Omoregie, S. Okoosi, A. Abdulsalami, B. Isah
Background: Malaria and HIV diseases kill millions of people yearly, and they are the scourges of developing nations. This study was conducted to determine the coinfections of malaria and HIV, and the effect of demographic characters on HIV-infected patients receiving highly active antiretroviral therapy (HAART) in Kogi State, Nigeria. Methods: Five hundred and eleven participants consisting of 411 (51 males and 360 females) HIV-infected patients on HAART and 100 (8 males and 92 females) apparently healthy HIV-noninfected individuals who served as controls were enrolled in this study. Blood sample was collected from each participant and malaria was diagnosed using the standard procedure. Results: An overall prevalence of 7.8% and 2% of malarial infection was observed in HIV-infected patients on HAART and non-HIV participants, respectively. The prevalence of malaria among HIV patients on HAART differed signifi cantly (P < 0.0001) among the local government councils, with patients from Ogori-Magongo having the least prevalence (0.0%). Age, gender, type of occupation, clinical manifestations, anemia, and CD4+ T-cell count <200 cells/μL affected the prevalence of malarial infection (P < 0.05) in this study. Conclusion: Diagnosis of malaria among HIV patients on HAART is advocated.
背景:疟疾和艾滋病每年夺去数百万人的生命,它们是发展中国家的祸患。本研究旨在确定尼日利亚科吉州疟疾和艾滋病毒的合并感染情况,以及人口统计学特征对接受高效抗逆转录病毒治疗(HAART)的艾滋病毒感染患者的影响。方法:共纳入511名参与者,其中包括411名(51名男性,360名女性)接受HAART治疗的hiv感染者和100名(8名男性,92名女性)表面健康的hiv非感染者作为对照组。从每位参与者身上采集血样,并使用标准程序诊断疟疾。结果:在HAART治疗的hiv感染者和非hiv参与者中,疟疾感染率分别为7.8%和2%。各地方政府委员会接受HAART治疗的HIV患者的疟疾患病率差异显著(P < 0.0001),其中Ogori-Magongo患者的患病率最低(0.0%)。年龄、性别、职业类型、临床表现、贫血、CD4+ t细胞计数<200细胞/μL影响本研究中疟疾感染率(P < 0.05)。结论:提倡对艾滋病患者进行HAART治疗以诊断疟疾。
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引用次数: 14
Assessment of the incidence of diarrhea in children under 5 years at the Institute of Child Health, Banzazzau, Zaria 对扎里亚邦扎扎乌儿童健康研究所5岁以下儿童腹泻发生率的评估
Pub Date : 1900-01-01 DOI: 10.4103/anm.anm_22_16
Ifeoma Bernadette Ucheh, Achadu Abraham Eleojo, Kpurkpur Tyoalumun, Drenkat Michael Nanpen
Introduction: This study was carried out to assess the incidence of diarrhoea in children under five years at the catchment community of Institute of Child Health (ICH), Banzazzau, Zaria, affiliated to Ahmadu Bello University Teaching Hospital Zaria. Aims: The study aim was to assess the incidence of diarrhoea amongst children under five years at the Institute of child health Banzazzau between January 2013 and December 2014. Settings and Design: The study was a retrospective study of the incidence of diarrhoea amongst children under five years at the Institute. Materials and Methods: The materials used for this survey include medical records, questionnaires, weighing scale and a metre rule. Hospital records of children presented with diarrhoea were reviewed to assess the occurrence of diarrhoea among under five. A total of 2,400 hospital records of children under 5 years over a period of 24 months (January 2013- December 2014) who attended the clinic were reviewed. Statistical Analysis Used: Data was analysed using SPSS, version 20.0 and anthropometric data was analysed using the WHO Anthro Software Package 2011. Results: The socio-demography of children seen in the hospital records showed a preponderance of male children over females that presented with diarrhoea (55.4%) and children within the aged 12-23 months had the most diarrhoeal cases (36.8%). Conclusions: Diarrheal disease assessed in under five years in the study area occurred more in male children who are between the ages of 12 to 23 months..
本研究旨在评估扎里亚邦扎扎乌儿童健康研究所(ICH)集水区5岁以下儿童腹泻发病率,该研究所隶属于扎里亚Ahmadu Bello大学教学医院。目的:本研究的目的是评估2013年1月至2014年12月期间班扎祖儿童保健研究所五岁以下儿童腹泻的发病率。背景和设计:本研究是对该研究所五岁以下儿童腹泻发病率的回顾性研究。资料和方法:本次调查使用的资料包括病历、问卷、称和米尺。对出现腹泻的儿童的医院记录进行了审查,以评估五岁以下儿童腹泻的发生率。对24个月(2013年1月至2014年12月)期间到该诊所就诊的2 400名5岁以下儿童的医院记录进行了审查。使用统计分析:数据分析使用SPSS 20.0版本,人体测量数据分析使用WHO anthroo软件包2011。结果:医院记录中儿童的社会人口统计显示,出现腹泻的男孩多于女孩(55.4%),12-23个月的儿童腹泻病例最多(36.8%)。结论:研究区5岁以下儿童腹泻多发生在12 ~ 23个月的男性儿童中。
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引用次数: 5
Pathologist-clinician collaboration: A marriage of necessity toward improving the quality of patient care 病理学家与临床医生的合作:改善病人护理质量的必要结合
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.163325
D. Suleiman
Collaboration between the pathologist and clinician has been found to be indispensable in improving the quality of patient care especially in, but not limited to, the area of cancer management and care.[2] Even though some sort of communication or collaboration exists between pathologists and their clinical colleagues, it is often circumstantial and usually occasioned by clinicopathological discrepancies recognized by the clinician. What is more sinister is the deliberate withholding of pertinent clinical information by the requesting physician who tries to justify this act by claiming that he/she would be preempting the pathologist by giving all the necessary clinical details. This practice is not only frustrating to the pathologist but is also a very dangerous for the patient with potentially enormous medical, legal, and financial consequences.[3,4]
病理学家和临床医生之间的合作已被发现是提高患者护理质量不可或缺的,特别是在但不限于癌症管理和护理领域。[2]尽管病理学家和他们的临床同事之间存在某种形式的交流或合作,但这往往是间接的,通常是由临床医生认识到的临床病理差异引起的。更险恶的是,提出请求的医生故意隐瞒相关的临床信息,并试图通过声称他/她将通过提供所有必要的临床细节来为这一行为辩护。这种做法不仅让病理学家感到沮丧,而且对病人来说也是非常危险的,可能会带来巨大的医疗、法律和经济后果。[3,4]
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引用次数: 6
A recommendation for primary operative management for low adhesive bowel obstruction 低粘连性肠梗阻的主要手术治疗建议
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.100202
David Irabor, O. Afuwape
Background : Our patients who required surgery for adhesive small bowel obstruction (ASBO) were noticed to have a peculiar association. This link was the type of surgery they had originally, operations in the pelvis or those in which the scars were below the umbilicus. These patients did not improve on conservative management. This study was then undertaken to investigate this trend and to recommend primary surgery for these group of patients, terming them as low ASBO for the purpose of the study. Aims : (1) To show that majority of patients with low adhesive bowel obstruction do not get better on conservative management. (2) To propose surgical operation as the primary management strategy of patients with low adhesive bowel obstruction. Settings and Design : The study is set in the gastrointestinal surgery unit of the University College Hospital (UCH) Ibadan. The hospital is located in Ibadan, the most populous city in West Africa with a population of roughly 2.5 million inhabitants. The UCH Ibadan handles more than 90% of all surgical cases in Ibadan. Materials and Methods : This is a retrospective descriptive study from April 2003 to February 2010 conducted on patients who were admitted on the service of the gastrointestinal surgery unit of the UCH Ibadan, Nigeria, with a diagnosis of ASBO and had surgery for relief of the condition. Admission records, operations registers, and patients′ case files were used in sourcing the data. Demographic indices such as age, sex, and type of previous operation were taken into account. Statistical Analysis : Stata 11.0 statistical software was used. Results : There were 4 male and 17 female patients giving a male: female ratio of roughly 1:4. Their ages ranged from 23 to 60 years. The global mean age was 40 years. The mean age for males was 31.5 years while for the female patients it was 42 years. Previous surgical operations showed that gynecological operations were in the majority (62%), followed by appendicectomy (24%) and colorectal surgery made up the rest (14%). Statistically, female sex, gynecological operations, and Lanz incisions for appendicectomy increase the chances of having surgery to relieve ASBO. Conclusions : We propose primary surgical treatment for low ASBO, especially those from gynecological operations and appendicectomy. Conservative management should be reserved as the initial treatment of non-low-level ASBO until other features prove otherwise.
背景:我们发现粘连性小肠梗阻(ASBO)需要手术治疗的患者有一种特殊的关联。这种联系是他们最初进行的手术类型,在骨盆或脐以下的疤痕进行的手术。这些患者在保守治疗后没有改善。研究人员随后对这一趋势进行了调查,并建议对这组患者进行初步手术,为研究的目的将其称为低ASBO。目的:(1)表明大多数低粘连性肠梗阻患者在保守治疗后并没有好转。(2)建议外科手术作为低粘连性肠梗阻患者的主要治疗策略。设置和设计:本研究设置在伊巴丹大学学院医院(UCH)胃肠外科。该医院位于伊巴丹,这是西非人口最多的城市,大约有250万居民。伊巴丹联合医院处理伊巴丹90%以上的外科病例。材料和方法:这是一项回顾性描述性研究,从2003年4月到2010年2月,对尼日利亚伊巴丹联合医院胃肠外科收治的诊断为ASBO并进行手术缓解病情的患者进行研究。数据来源采用了住院记录、手术登记簿和患者病例档案。考虑了年龄、性别、既往手术类型等人口统计指标。统计学分析:采用Stata 11.0统计软件。结果:男性4例,女性17例,男女比例约为1:4。他们的年龄从23岁到60岁不等。全球平均年龄为40岁。男性患者平均年龄为31.5岁,女性患者平均年龄为42岁。既往手术显示,妇科手术占多数(62%),其次是阑尾切除术(24%)和结直肠手术(14%)。据统计,女性、妇科手术和阑尾切除术的Lanz切口增加了手术缓解ASBO的机会。结论:建议对低ASBO患者进行手术治疗,尤其是妇科手术和阑尾切除术后的低ASBO患者。非低级别反社会行为障碍的初始治疗应保留保守管理,直到其他特征证明并非如此。
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引用次数: 0
Anaphylactic reaction or anaphylactoid reaction? 过敏反应还是类过敏反应?
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.84227
Aparna Williams, Dootika Liddle
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引用次数: 0
Initial outcome following invasive cardiac electrophysiologic studies and radiofrequency ablation of ventricular tachycardia 有创心脏电生理研究和射频消融治疗室性心动过速的初步结果
Pub Date : 1900-01-01 DOI: 10.4103/0331-3131.189799
K. Uwanuruochi, Sabari Saravanan, Anita Ganasekar, Benjamin Solomon, Ravikumar Murugesan, Ruchit A Shah, Jaishankar Krishnamoorthy, U. Pandurangi
Background: Cardiac electrophysiologic study (EPS) and radiofrequency (RF) ablation have become an established mode of treatment for patients with refractory arrhythmias. These procedures are carried out regularly at the cardiac catheterization laboratory of Madras Medical Mission India. Objective: The purpose of this study was to evaluate our experience with cardiac EPSs and Radiofrequency ablations (RFAs) of ventricular tachycardia (VT). Methods: This was a retrospective study carried out in the Cardiac Electrophysiology Department of the Institute of Cardiovascular Diseases, Madras Medical Mission, India. All cases diagnosed to have VT following cardiac EPS between January 2010 and April 2014 were selected for the study. The records which were obtained from the Cardiac Electrophysiology Clinical Research Office of Madras Medical Mission were reviewed. One hundred and thirteen cases were chosen for the analysis, using SPSS statistical software version 15. Results: There were 113 patients, comprised 78 males and 35 females. The mean age was 48.79 years. Common etiologic classes of VT were idiopathic outflow tract VT - 50.4%, ischemic heart disease - 20.4%, arrhythmogenic right ventricular cardiomyopathy (ACMP) - 11.5%, and idiopathic dilated cardiomyopathy (IDCM) - 12.4%. Ablation was attempted in 92 (82.1%). The initial outcome was highest in IDCM, 87.5%, and least in ACMP, 50.0%. Conclusions: Treatment of VT by RFA is comparatively effective and safe.
背景:心脏电生理研究(EPS)和射频消融(RF)已成为治疗难治性心律失常的一种既定模式。这些程序在印度马德拉斯医疗团的心导管化验室定期进行。目的:本研究的目的是评价我们的心脏EPSs和射频消融术治疗室性心动过速(VT)的经验。方法:这是一项在印度马德拉斯医疗中心心血管疾病研究所心脏电生理科进行的回顾性研究。所有2010年1月至2014年4月期间诊断为心性EPS后室速的病例均被纳入研究。审查了从马德拉斯医疗特派团心脏电生理临床研究办公室获得的记录。选取113例病例进行分析,采用SPSS统计软件15版。结果:113例患者,其中男性78例,女性35例。平均年龄48.79岁。常见的VT病因分类为特发性流出道VT - 50.4%,缺血性心脏病- 20.4%,心律失常性右室心肌病(ACMP) - 11.5%,特发性扩张型心肌病(IDCM) - 12.4%。92例(82.1%)尝试消融。IDCM的初始转归率最高,为87.5%,ACMP最低,为50.0%。结论:RFA治疗室速是一种相对安全有效的方法。
{"title":"Initial outcome following invasive cardiac electrophysiologic studies and radiofrequency ablation of ventricular tachycardia","authors":"K. Uwanuruochi, Sabari Saravanan, Anita Ganasekar, Benjamin Solomon, Ravikumar Murugesan, Ruchit A Shah, Jaishankar Krishnamoorthy, U. Pandurangi","doi":"10.4103/0331-3131.189799","DOIUrl":"https://doi.org/10.4103/0331-3131.189799","url":null,"abstract":"Background: Cardiac electrophysiologic study (EPS) and radiofrequency (RF) ablation have become an established mode of treatment for patients with refractory arrhythmias. These procedures are carried out regularly at the cardiac catheterization laboratory of Madras Medical Mission India. Objective: The purpose of this study was to evaluate our experience with cardiac EPSs and Radiofrequency ablations (RFAs) of ventricular tachycardia (VT). Methods: This was a retrospective study carried out in the Cardiac Electrophysiology Department of the Institute of Cardiovascular Diseases, Madras Medical Mission, India. All cases diagnosed to have VT following cardiac EPS between January 2010 and April 2014 were selected for the study. The records which were obtained from the Cardiac Electrophysiology Clinical Research Office of Madras Medical Mission were reviewed. One hundred and thirteen cases were chosen for the analysis, using SPSS statistical software version 15. Results: There were 113 patients, comprised 78 males and 35 females. The mean age was 48.79 years. Common etiologic classes of VT were idiopathic outflow tract VT - 50.4%, ischemic heart disease - 20.4%, arrhythmogenic right ventricular cardiomyopathy (ACMP) - 11.5%, and idiopathic dilated cardiomyopathy (IDCM) - 12.4%. Ablation was attempted in 92 (82.1%). The initial outcome was highest in IDCM, 87.5%, and least in ACMP, 50.0%. Conclusions: Treatment of VT by RFA is comparatively effective and safe.","PeriodicalId":331118,"journal":{"name":"Annals of Nigerian Medicine","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123513102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Annals of Nigerian Medicine
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