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Clinical profile and mortality determinants in hair dye poisoning 染发剂中毒的临床特征和死亡率决定因素
Pub Date : 2014-07-01 DOI: 10.4103/0331-3131.153359
D. Balasubramanian, S. Subramanian, K. Shanmugam
Introduction: India has a high suicide rate, and a large proportion of these suicides occur through poisoning. Poisoning by hair dye has been increasing, and in some regions, constitutes a large proportion of the poisoning cases. Aims: To determine the clinical and biochemical features of hair dye poisoning, and to identify factors affecting mortality among these cases of hair dye poisoning. Subjects and Methods: A cross-sectional study conducted from April to December 2010 in Thoothukudi, Tamil Nadu, among 125 cases of hair dye poisoning. Cases with the prior history of cardiac/respiratory illness, seizure disorder, and those consuming a mixture of poisons were excluded from the study. A standardized questionnaire was administered. Biochemical and other investigations were carried out; and patient outcomes were documented. Statistical Analysis Used: The results were compiled and analyzed using Statistical Package for the Social Sciences (version 20) software. Chi-square test, Mann-Whitney U-test, and Kruskal-Wallis test at 5% level of significance was used to analyze the data. Results: Among the 125 cases, 68.8% were females, and the overall median age was 24 (20-30.5) years. The median time of presentation was 155 min (40-275), and the average amount of hair dye consumed was about 50.0 mls (25-55 mls). Almost 68.8% of the cases developed oropharyngeal edema, and among them, 57 (66.28%) had an emergency tracheostomy performed. About 27.2% of the patients died. Conclusions: The time of presentation to the hospital is an important risk factor for developing oropharyngeal edema, which in turn determines the risk of mortality. Females, especially those in the younger age groups should be targeted for supportive and preventive strategies, so as to reduce the incidence of hair dye poisoning.
引言:印度的自杀率很高,其中很大一部分是通过中毒自杀的。染发剂中毒一直在增加,在一些地区,染发剂中毒占中毒病例的很大比例。目的:了解染发剂中毒的临床及生化特点,探讨染发剂中毒患者死亡的影响因素。研究对象和方法:2010年4月至12月在泰米尔纳德邦Thoothukudi进行了一项横断面研究,共125例染发剂中毒。既往有心脏/呼吸系统疾病史、癫痫发作史和混合中毒史的病例被排除在研究之外。进行了标准化问卷调查。进行了生化和其他调查;病人的结果被记录下来。使用统计分析:使用Statistical Package for The Social Sciences (version 20)软件对结果进行编译和分析。采用5%显著性水平下的卡方检验、Mann-Whitney u检验和Kruskal-Wallis检验对数据进行分析。结果:125例患者中,女性占68.8%,总体中位年龄24(20 ~ 30.5)岁。平均出现时间为155分钟(40-275分钟),染发剂的平均用量约为50.0毫升(25-55毫升)。68.8%的患者出现口咽水肿,其中57例(66.28%)急诊行气管切开术。约27.2%的患者死亡。结论:就诊时间是发生口咽水肿的重要危险因素,进而决定死亡风险。应针对女性,特别是年轻年龄组的女性采取支持和预防策略,以减少染发剂中毒的发生率。
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引用次数: 15
Assessment of birth preparedness and complication readiness among pregnant women attending Primary Health Care Centres in Edo State, Nigeria 评估在尼日利亚埃多州初级保健中心就诊的孕妇的分娩准备和并发症准备情况
Pub Date : 2014-07-01 DOI: 10.4103/0331-3131.153358
Ekaete Alice Tobin, A. Ofili, Nkemka Enebeli, Ogochukwu Enueze
Background: The principle and practice of birth preparedness and complication readiness (BP/CR) in resource-poor settings have the potential of reducing maternal, and neonatal morbidity and mortality rates. Aim: The aim was to assess BP/CR among pregnant women attending Antenatal care in Primary Health Care Centres in Oredo Local Government Area (LGA) in Benin City, Edo State. Materials and Methods: A descriptive cross-sectional study carried out among pregnant women attending antenatal clinic in Primary Health Centres in Oredo LGA. Data were collected using structured questionnaires, and analyzed using the Statistical Package for Social sciences (SPSS) Version 16.0. Descriptive data were presented in frequency tables. Statistical testing using Chi-square was carried out with level of significance set as P < 0.05. Results: One hundred and fourteen pregnant women (49.6%) were aware of at least one danger sign associated with pregnancy, labor, and postpartum, while 201 women (87.4%) had identified a skilled birth attendant. Twenty-six (11.3%) had saved money for obstetric care, and 143 (62.2%) had purchased or made plans to purchase birth supplies. Two hundred and one (87.4%) respondents were found to be well-prepared for the birth. Having a tertiary education and being married were factors found to be significantly associated with BP. Conclusion: Majority of the women had BP/CR in place. However, emphasis should be placed on identifying target groups and practice gaps, for intensified health education.
背景:在资源贫乏的环境中,分娩准备和并发症准备(BP/CR)的原则和实践具有降低孕产妇和新生儿发病率和死亡率的潜力。目的:目的是评估在Edo州贝宁市Oredo地方政府区(LGA)初级卫生保健中心接受产前护理的孕妇的BP/CR。材料和方法:一项描述性横断面研究对在奥雷多州州初级保健中心产前诊所就诊的孕妇进行了调查。使用结构化问卷收集数据,并使用社会科学统计软件包(SPSS) 16.0版本进行分析。描述性数据以频率表的形式呈现。采用卡方检验,显著性水平设为P < 0.05。结果:114名孕妇(49.6%)了解至少一种与妊娠、分娩和产后相关的危险信号,201名孕妇(87.4%)认识熟练的助产士。26人(11.3%)为产科护理省钱,143人(62.2%)购买或计划购买分娩用品。211名(87.4%)受访者对分娩做好了充分准备。受过高等教育和已婚是与BP显著相关的因素。结论:多数女性血压/CR正常。然而,应强调确定目标群体和实践差距,以加强健康教育。
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引用次数: 26
Profile of stroke patients seen in a tertiary health care center in Nigeria 尼日利亚三级卫生保健中心中风患者的概况
Pub Date : 2013-07-01 DOI: 10.4103/0331-3131.133097
S. Abubakar, A. Sabir
Background: The profile of patients seen with acute stroke has been sparsely described in north-western Nigeria, even though stroke constitutes an important cause of severe disability in adults. Aims: (1) The primary aim is to determine the clinical and socio-demographic profile of stroke patients seen in a tertiary hospital. (2) The secondary aim is to determine the 30-day case fatality. Patients and Methods: A retrospective study carried out using the case records of patients admitted from January 2007 to December 2009 with the clinical diagnosis of stroke at Usmanu Danfodiyo University Teaching Hospital. Relevant clinical data were extracted using a structured questionnaire designed for the study. Results: A total of 370 case files with the clinical diagnosis of stroke were traced, but only 260 had complete information. The mean age of patients was 55.7 ± 14.3 years; hypertension (74.6%) was the most common modifiable risk factor for stroke followed by diabetes mellitus (8.8%). Stroke constituted 1.2% of all hospital admissions and 8.5% of death in the medical units. The 24-h and 30-day case fatalities were 11.9% and 38.4%, respectively. The mean duration of hospitalization for stroke survivors was 21 days, but the duration of hospitalization prior to death for those that died was 4 days. Conclusion: The 30-day case fatality of acute stroke was high and hypertension was the most common modifiable risk factor for stroke. Prompt and adequate measures should be taken to improve outcome of stroke.
背景:尽管中风是导致成人严重残疾的一个重要原因,但在尼日利亚西北部,急性中风患者的情况却很少被报道。目的:(1)主要目的是确定在三级医院就诊的脑卒中患者的临床和社会人口特征。(2)次要目的是确定30天病死率。患者与方法:回顾性分析2007年1月至2009年12月在乌斯马努丹福迪约大学教学医院住院的临床诊断为脑卒中患者的病例记录。使用为研究设计的结构化问卷提取相关临床数据。结果:共追踪到临床诊断为脑卒中的病例370例,信息完整的仅有260例。患者平均年龄55.7±14.3岁;高血压(74.6%)是卒中最常见的可改变危险因素,其次是糖尿病(8.8%)。中风占所有住院人数的1.2%,占医疗单位死亡人数的8.5%。24小时和30天病死率分别为11.9%和38.4%。中风幸存者的平均住院时间为21天,但死亡前的住院时间为4天。结论:急性脑卒中30天病死率高,高血压是卒中最常见的可改变危险因素。应及时采取适当措施改善脑卒中预后。
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引用次数: 14
Interictal electroencephalography in patients with epilepsy in northwestern Nigeria 尼日利亚西北部癫痫患者的间期脑电图
Pub Date : 2013-07-01 DOI: 10.4103/0331-3131.133096
L. Owolabi, S. Shehu, S. Owolabi, M. Umar
Background: Different studies have reported various frequencies of electroencephalographic (EEG) abnormalities in patients with epilepsy. There is, however, a paucity of data on EEG in Nigeria; hence, the need for this study. Objective: The objective of the following study was to evaluate interictal EEG pattern in patients with epilepsy in Kano, Northwestern Nigeria. Subjects and Methods: A cross-sectional study involving the analysis of EEGs of consecutive patients with clinical diagnosis of epilepsy over a 5 year period at two diagnostic centers in Kano, northwestern Nigeria. Information on socio-demographic and seizure characteristics was obtained. The recordings from patients were obtained using the standard methods and interpreted by two of the investigators. The International Federation of Societies for Electroencephalography and Clinical Neurophysiology definition of interictal epileptiform discharges (interictal epileptiform activity [IEA]) was adopted for the study. Result: Out of 2219 patients referred for EEG at the two diagnostic centers during the study period, 2041 (92%) patients had a clinical diagnosis of epilepsy. Their age ranged between 0.04 and 75 years, with a mean age of 22.8 ± 14.9 years. Overall, EEG was abnormal in 1178 (57.7%) and 919 (45.1%) had an epileptiform pattern. A total of 1691 patients had hyperventilation (HV) and response to HV was unremarkable in 1286 (76%) of them. Out of 405 who had remarkable changes on HV; 302 had increase in epileptiform discharges, whereas 103 had abnormal discharges only on HV. Seventeen (89.5%) out of 19 patients with 3 Hz spike and wave complexes had activation by HV. The most common IEA were focal spike/sharp and wave and generalized spike/sharp and slow waves. More antiepileptic drug (AED) naive patients (678) than those that were on AED (500) had EEG abnormality and the difference was statistically significant, P < 0.001. Conclusion: The study showed that the occurrence of interictal EEG abnormality in patients with epilepsy was about 58%. The proportion of interictal epileptiform discharges was 45% in routine first EEG studies. Among those with epileptiform activity, generalized sharp and wave complexes and focal sharp and slow wave complexes were the most common findings.
背景:不同的研究报道了癫痫患者脑电图(EEG)异常的不同频率。然而,尼日利亚缺乏脑电图数据;因此,有必要进行这项研究。目的:以下研究的目的是评估尼日利亚西北部卡诺癫痫患者的间期脑电图模式。研究对象和方法:一项横断面研究,对尼日利亚西北部卡诺两个诊断中心连续5年临床诊断为癫痫的患者的脑电图进行分析。获得了有关社会人口统计和癫痫发作特征的信息。使用标准方法获得患者的录音,并由两名研究人员进行解释。本研究采用国际脑电图和临床神经生理学联合会对癫痫样间期放电(interictal epileptiform activity [IEA])的定义。结果:在研究期间,在两个诊断中心转诊的2219例脑电图患者中,2041例(92%)患者临床诊断为癫痫。年龄0.04 ~ 75岁,平均22.8±14.9岁。脑电图异常1178例(57.7%),癫痫样919例(45.1%)。1691例患者出现换气过度(HV),其中1286例(76%)对HV无明显反应。在405名hiv有显著变化的人中;302例癫痫样放电增加,103例仅在HV组出现异常放电。19例3hz峰波复合物患者中有17例(89.5%)被HV激活。最常见的国际能源机构是焦点尖峰/尖峰和波和广义尖峰/尖峰和慢波。抗癫痫药物(AED)初治组(678例)脑电图异常高于使用AED组(500例),差异有统计学意义(P < 0.001)。结论:研究表明癫痫患者间期脑电图异常发生率约为58%。常规首次脑电图中癫痫样放电的发生率为45%。在癫痫样活动的患者中,广泛性尖波复合体和局灶性尖波慢波复合体是最常见的发现。
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引用次数: 9
Multidrug resistant Mycobacterium tuberculosis in cutaneous tuberculosis in China 中国皮肤结核的耐多药结核分枝杆菌
Pub Date : 2013-07-01 DOI: 10.4103/0331-3131.133100
X. Tao, Yan-shi Mo, Y. Guan
We describe a male patient who presented with a 2 years history of recurrent ulcers and erythematous plaques on the buttocks. Skin biopsy and tissue culture on Lowenstein Jensen media resulted in the isolation of Mycobacteria, which was further identified as Mycobacterium tuberculosis (MTB) by polymerase chain reaction. The results of drug susceptibility tests showed that the MTB isolated was resistant to isoniazid (INH), rifampicin (RIF), ethambutol (ETH) and rifapentine (RFT). During 7 years of follow-up after discharge from hospital admission, the erythematous plaques and atrophic scars remained confined to the patient′s buttocks. This is the first reported case of cutaneous multidrug-resistant tuberculosis (MDR-TB) in China. Given the increasing incidence of MDR-TB in china, our case report calls for heightened clinical awareness and improved facilities to confirm the diagnosis of MDR-TB.
我们描述了一个男性病人谁提出了2年的历史复发性溃疡和臀部红斑斑块。皮肤活检和Lowenstein Jensen培养基组织培养分离出分枝杆菌,经聚合酶链反应进一步鉴定为结核分枝杆菌(MTB)。药敏试验结果表明,分离的结核分枝杆菌对异烟肼(INH)、利福平(RIF)、乙胺丁醇(ETH)和利福喷丁(RFT)均耐药。在出院后的7年随访中,红斑斑块和萎缩性疤痕仍然局限于患者的臀部。这是中国首例皮肤耐多药结核病(MDR-TB)报告病例。鉴于耐多药结核病在中国的发病率不断上升,我们的病例报告呼吁提高临床认识并改善确诊耐多药结核病的设施。
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引用次数: 3
Recurrent transient ischemic attacks due to vascular steal syndrome secondary to the Paget′s disease of bone: A rare presentation 继发于骨佩吉特病的血管偷窃综合征引起的复发性短暂性脑缺血发作:一种罕见的表现
Pub Date : 2013-07-01 DOI: 10.4103/0331-3131.133102
A. Pai, K. Balakumar, S. Shankar, V. Umadevi, B. Manash, S. Narayanasamy
Paget′s disease of bone (osteitis deformans) is a condition of unknown etiology, characterized by rapid bone remodeling and formation of new bone that is structurally abnormal. A wide range of clinical manifestations are reported among patients with Paget′s disease including bone pain, fractures, secondary osteoarthritis, hearing loss, and syndrome of neurological compression secondary to vascular steal phenomenon. Here we report a rare case of recurrent transient ischemic attacks due to vascular steal syndrome secondary to Paget′s disease of bone.
骨Paget病(骨炎变形)是一种病因不明的疾病,其特征是骨快速重塑和新骨形成,结构异常。Paget病患者的临床表现广泛,包括骨痛、骨折、继发性骨关节炎、听力丧失和血管偷窃现象继发的神经压迫综合征。我们在此报告一例罕见的因骨佩吉特病继发的血管偷窃综合征而引起的复发性短暂性脑缺血发作。
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引用次数: 0
Discharge against medical advice: Experience from a rural Nigerian hospital 不遵医嘱出院:尼日利亚一家农村医院的经验
Pub Date : 2013-07-01 DOI: 10.4103/0331-3131.133098
J. Fadare, O. Babatunde, T. Olanrewaju, O. Busari
Introduction: Discharge against medical advice (DAMA) is a worldwide problem with negative health and socioeconomic effects. Factors that have been implicated as causes or contributing to DAMA include financial constraints, lack of health insurance, deteriorating clinical condition of the patient, and problematic doctor-patient relationships. Aims: determine the incidence and profiles ofDAMA on the medical wards, so as to allows for evidence-based interventions to reduce this problem to a minimum. Materials and Methods: This was a case-control study carried out on the medical wards of Federal Medical Center, Ido-Ekiti, South-West Nigeria. The medical records of all patients admitted to the male and female medical wards between January 2008 and April 2011 were reviewed. After being identified through the admission/discharge log, patients who were DAMA and a similar number of patients with regular discharge had their case notes retrieved. Information extracted included bio-data, diagnosis, duration of hospital stay, and reason for discharge. Results: One hundred and thirty-eight patients representing 7.2% were DAMA during the study period. Ninety five cases had complete medical records, and full analysis was carried out on these and 94 other cases with regular discharge as control. The mean age of the DAMA cases was 50.8 ± 18.3 years, with 58 (61.1%) of these patients being male; while the mean age of the control group was 54.1 ± 16.5, of which 54 (57.4%) were male. The mean duration of admission for patients with DAMA was 10.4 ± 9.2 days as against 11.9 ± 10 in the control group, a difference that is not statistically significant. The associations between type of discharge, sex, and duration of admission are shown through odds ratios of 0.883 and 0.833 respectively. Financial problems (48%), lack of clinical improvement (28.8%) and leaving to seek alternative/complimentary medical care (23.1%) were the factors found to be responsible for DAMA in the study. Conclusion: The incidence of discharge against medicine is high in this study. There is a need for all stakeholders to evaluate factors responsible for DAMA, with the aim of reducing this trend.
医嘱出院(DAMA)是一个世界性的问题,具有负面的健康和社会经济影响。被认为是导致或促成DAMA的因素包括财政拮据、缺乏医疗保险、患者临床状况恶化以及医患关系问题。目的:确定病房dama的发生率和概况,以便采取循证干预措施,将这一问题减少到最低限度。材料和方法:这是一项在尼日利亚西南部伊多埃基蒂联邦医疗中心病房进行的病例对照研究。审查了2008年1月至2011年4月期间入住男病房和女病房的所有病人的医疗记录。在通过入院/出院日志确定后,检索DAMA患者和类似数量的定期出院患者的病例记录。提取的信息包括生物资料、诊断、住院时间和出院原因。结果:138例患者在研究期间发生DAMA,占7.2%。病历完整者95例,对照正常出院者94例,进行全面分析。DAMA患者平均年龄为50.8±18.3岁,男性58例(61.1%);对照组平均年龄54.1±16.5岁,其中男性54例(57.4%)。DAMA患者的平均住院时间为10.4±9.2天,而对照组为11.9±10天,差异无统计学意义。出院类型、性别和住院时间的比值比分别为0.883和0.833。经济问题(48%)、缺乏临床改善(28.8%)和离开医院寻求替代/免费医疗(23.1%)是研究中发现的导致DAMA的因素。结论:本组患者抗药出院发生率较高。所有利益相关者都需要评估导致DAMA的因素,以减少这一趋势。
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引用次数: 14
Primary volvulus of the small intestine 小肠的原肠扭转
Pub Date : 2013-07-01 DOI: 10.4103/0331-3131.133104
N. Ali, Mohammed Mubarak, Yakubu Ali
Small bowel volvulus is an occasional cause of mechanical intestinal obstruction in our practice causing diagnostic problems. We report a case of primary small bowel volvulus with gangrene. A 30-year-old farmer who presented with features of acute intestinal obstruction, which at laparotomy revealed a primary small bowel volvulus with a gangrenous loop of ileum. The patient was resuscitated and had exploratory laparotomy; with operative findings of a twisted loop of gangrenous ileum adjoining the ileocecal valve. This was resected and an end to end ileotransverse anastomosis effected. The patient made an uneventful recovery and was discharged on the 7 th postoperative day. Primary small bowel volvulus should be suspected in acute intestinal obstruction. It presents as an acute abdomen due to occlusion of bowel lumen alone or with obstruction of its blood supply leading to gangrene. Treatment includes resection and end to end anastomosis, which can help to reduce mortality and morbidity.
小肠扭转是机械性肠梗阻的偶然原因,在我们的实践中引起诊断问题。我们报告一例原发性小肠扭转伴坏疽。一位30岁的农民,以急性肠梗阻为特征,开腹时发现原发性小肠扭转伴坏疽性回肠袢。患者经复苏并开腹探查;手术发现在回盲瓣附近有一个扭曲的坏疽回袢。切除后行端到端回肠横切吻合。患者顺利康复,于术后第7天出院。急性肠梗阻应怀疑原发性小肠扭转。它表现为急性腹部,仅因肠腔闭塞或其血液供应受阻而导致坏疽。治疗包括切除和端到端吻合,可以帮助降低死亡率和发病率。
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引用次数: 2
Age at menarche and prevalence of menstrual abnormalities among adolescents in Zaria, northern Nigeria 尼日利亚北部扎里亚地区青少年月经初潮年龄和月经异常患病率
Pub Date : 2013-07-01 DOI: 10.4103/0331-3131.133099
H. Sulayman, N. Ameh, A. Adesiyun, I. Ozed-Williams, A. Ojabo, S. Avidime, Nosa E Enobun, A. Yusuf, Abdulsalam Muazu
Background: Nigerian adolescents constitute about 20% of the total population. Problems associated with menstruation affect 75% of adolescent females in both the developing and the developed world. Objectives: The objective of this study is to establish the age at menarche and menstrual abnormalities among adolescents in secondary schools in Zaria. Materials and Methods: A descriptive cross sectional study in which a self-administered pretested, semi-structured questionnaire in english was administered to 535 female secondary school students in Zaria, northern Nigeria. The students were selected from five schools that were chosen by simple random sampling from a list of schools in Zaria metropolis. Information obtained included age at menarche and menstruation related issues. Results: Of the 535 female secondary school students interviewed, 448 (83.7%) were in senior secondary school. The mean age of the respondents was 15.35 ± 1.48 years. The average age at menarche was 12.53 ± 1.33 years. Most respondents, 369 (69.0%) experienced regular menses. The average duration of menstruation was 5.45 ± 1.81 days in 354 (66.2%) of the respondents. Three hundred and forty-four (64.3%) of the respondents had dysmenorrhea, and it was severe in 229 (66.6%) of them. Only, 137 (25.6%) experienced premenstrual symptoms, the most common symptom being breast tenderness in 62 respondents (45.2%). Conclusion: The age at menarche and the menstrual pattern amongst adolescents in Zaria, northern Nigeria is similar to findings from other parts of Nigeria as well as from other parts of the world. Further studies are however needed to explore the full range of menstrual abnormalities that can occur in the adolescent age group.
背景:尼日利亚青少年约占总人口的20%。与月经有关的问题影响着发展中国家和发达国家75%的青春期女性。目的:本研究的目的是确定初潮年龄和月经异常的青少年在中学在扎里亚。材料和方法:一项描述性横断面研究,在该研究中,对尼日利亚北部扎里亚的535名女中学生进行了自我管理的预测试半结构化英语问卷调查。这些学生是通过简单随机抽样从扎里亚大都市的学校名单中选出的五所学校中选出的。获得的信息包括初潮年龄和月经相关问题。结果:受访的535名女中学生中,高中学生448名,占83.7%。受访者平均年龄15.35±1.48岁。初潮平均年龄为12.53±1.33岁。大多数受访者,369人(69.0%)月经规律。354人(66.2%)平均月经持续时间为5.45±1.81天。344人(64.3%)有痛经,其中重度229人(66.6%)有痛经。只有137人(25.6%)出现经前症状,62人(45.2%)最常见的症状是乳房压痛。结论:尼日利亚北部扎里亚青少年的月经初潮年龄和月经模式与尼日利亚其他地区以及世界其他地区的调查结果相似。然而,需要进一步的研究来探索可能发生在青少年年龄组的月经异常的全部范围。
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引用次数: 13
Controlling the spread of carbapenemase-producing Gram-negative bacteria 控制产生碳青霉烯酶的革兰氏阴性菌的传播
Pub Date : 2013-07-01 DOI: 10.4103/0331-3131.133094
S. Aliyu
Corresponding Author: Dr. Shamsudin Aliyu, Department of Medical Microbiology, Ahmadu Bello University Teaching Hospital, Shika, Zaria, Kaduna State, Nigeria. E-mail: shamsualiyu@gmail.com The rapid spread of carbapenemase producing Gram-negatives (CPGNs) continues to pose a significant health threat globally. The potential threat to patients and health personnel is unprecedented. This has heightened the global awareness of the need to prioritize infection prevention and control (IPC) strategies, with the aim of reducing the burden of infection caused by these bacteria. Developing countries have experienced unfavorable trends in antimicrobial resistance.[1] CPGNs have now emerged as a significant threat in Africa.[2] Implementation of effective infection control strategies are hampered by many factors, some of which are specific to developing countries. An understanding of the basic principles of CPGN IPC is crucial to the battle against these multidrug resistant bacteria.
通讯作者:Shamsudin Aliyu博士,医学微生物科,尼日利亚卡杜纳州扎里亚什卡Ahmadu Bello大学教学医院。碳青霉烯酶产生革兰氏阴性(CPGNs)的迅速传播继续在全球范围内构成重大健康威胁。对患者和医务人员的潜在威胁是前所未有的。这提高了全球对优先考虑感染预防和控制(IPC)战略的必要性的认识,目的是减轻这些细菌引起的感染负担。发展中国家在抗菌素耐药性方面经历了不利的趋势。[1]CPGNs现在已经成为非洲的重大威胁。[2]实施有效的感染控制战略受到许多因素的阻碍,其中一些因素是发展中国家特有的。了解CPGN IPC的基本原理对于对抗这些多重耐药细菌至关重要。
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引用次数: 0
期刊
Annals of Nigerian Medicine
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