Infection Prevention in Practice最新文献_第2页

Evaluation of hand hygiene implementation in hospitals in the post-war Tigray region of Ethiopia, using the WHO Hand Hygiene Self-Assessment Framework 使用世卫组织手卫生自我评估框架，评价战后埃塞俄比亚提格雷地区医院的手卫生实施情况

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-10-31 DOI: 10.1016/j.infpip.2025.100490

Akeza Awealom Asgedom , Bente Elisabeth Moen , Ana Lorena Ruano

Background

Healthcare-associated infections are a major cause of morbidity and mortality among health personnel worldwide. The World Health Organization's (WHO) multi-modal hand hygiene tool has shown inadequate hand hygiene levels in various sub-Saharan countries. We have applied it here to describe the hand hygiene level in public health facilities in Tigray, Ethiopia.

Methods

A cross-sectional study was conducted from June to July 2024 in all accessible public health facilities. An interview-based WHO hand hygiene self-assessment framework (HHSAF) tool was used for data collection. Descriptive analyses and independent t-test were used to analyse data.

Results

A total of 33 facilities (two referral, 10 general, and 21 primary hospitals) from six accessible zones of Tigray participated in the survey. The mean age of the respondents was 35 years (SD: 8) with a mean service duration of nine years (SD: 7). Most respondents were infection prevention and control (IPC) focal persons (66.7%), followed by chief executive officers (9.1%). The overall HHSAF score was 126 (range: 15–318), indicating a basic hand hygiene level. Seventeen facilities (51.5%) had inadequate hand hygiene levels, 13 (39.4%) had basic hand hygiene level, three (9.1%) had an intermediate hand hygiene level, and none had an advanced hand hygiene level.

Conclusions

Hand hygiene levels were unsatisfactory in post-war Tigray and were limited across all zones and types of facility, posing an increased risk of infection for healthcare personnel. Improvements in hand hygiene practices and IPC capacity building are essential to prevent healthcare-associated infections. Longitudinal research on hand hygiene level monitoring is recommended.

背景：卫生保健相关感染是全世界卫生人员发病和死亡的主要原因。世界卫生组织（世卫组织）的多模式手卫生工具显示，撒哈拉以南非洲各国的手卫生水平不足。我们在这里应用它来描述埃塞俄比亚提格雷公共卫生设施的手部卫生水平。方法采用横断面研究方法，于2024年6 - 7月在所有可达的公共卫生机构进行调查。采用基于访谈的世卫组织手卫生自我评估框架（HHSAF）工具收集数据。采用描述性分析和独立t检验对数据进行分析。结果来自提格雷6个可通达区的33家医院（2家转诊医院、10家综合医院和21家基层医院）参与了调查。受访者的平均年龄为35岁（SD: 8），平均服务时间为9年（SD: 7）。受访者中感染预防和控制（IPC）联络人最多（66.7%），其次是首席执行官（9.1%）。总体HHSAF得分为126（范围：15-318），表示基本的手卫生水平。手卫生不达标17家（51.5%），基本手卫生13家（39.4%），中级手卫生3家（9.1%），高级手卫生0家。结论提格雷战后卫生水平不理想，所有区域和设施类型的卫生水平有限，增加了卫生保健人员的感染风险。改善手部卫生习惯和IPC能力建设对于预防卫生保健相关感染至关重要。建议对手卫生水平监测进行纵向研究。

{"title":"Evaluation of hand hygiene implementation in hospitals in the post-war Tigray region of Ethiopia, using the WHO Hand Hygiene Self-Assessment Framework","authors":"Akeza Awealom Asgedom , Bente Elisabeth Moen , Ana Lorena Ruano","doi":"10.1016/j.infpip.2025.100490","DOIUrl":"10.1016/j.infpip.2025.100490","url":null,"abstract":"<div><h3>Background</h3><div>Healthcare-associated infections are a major cause of morbidity and mortality among health personnel worldwide. The World Health Organization's (WHO) multi-modal hand hygiene tool has shown inadequate hand hygiene levels in various sub-Saharan countries. We have applied it here to describe the hand hygiene level in public health facilities in Tigray, Ethiopia.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted from June to July 2024 in all accessible public health facilities. An interview-based WHO hand hygiene self-assessment framework (HHSAF) tool was used for data collection. Descriptive analyses and independent <em>t</em>-test were used to analyse data.</div></div><div><h3>Results</h3><div>A total of 33 facilities (two referral, 10 general, and 21 primary hospitals) from six accessible zones of Tigray participated in the survey. The mean age of the respondents was 35 years (SD: 8) with a mean service duration of nine years (SD: 7). Most respondents were infection prevention and control (IPC) focal persons (66.7%), followed by chief executive officers (9.1%). The overall HHSAF score was 126 (range: 15–318), indicating a basic hand hygiene level. Seventeen facilities (51.5%) had inadequate hand hygiene levels, 13 (39.4%) had basic hand hygiene level, three (9.1%) had an intermediate hand hygiene level, and none had an advanced hand hygiene level.</div></div><div><h3>Conclusions</h3><div>Hand hygiene levels were unsatisfactory in post-war Tigray and were limited across all zones and types of facility, posing an increased risk of infection for healthcare personnel. Improvements in hand hygiene practices and IPC capacity building are essential to prevent healthcare-associated infections. Longitudinal research on hand hygiene level monitoring is recommended.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 4","pages":"Article 100490"},"PeriodicalIF":1.9,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145568215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of a nudge-based intervention on hand soap usage in a Japanese Hospital: interrupted time series analysis 日本一家医院轻推干预对洗手液使用的影响：中断时间序列分析

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-10-27 DOI: 10.1016/j.infpip.2025.100494

Tetsuji Morishita , Masayoshi Monji , Masao Kuwabara , Shin Lee , Makoto Hayashi , Hisashi Tsurumi , Hidetoshi Matsunami

Background

This study aimed to evaluate the effectiveness of nudge-based messages on hand soap usage in a Japanese hospital setting.

Methods

Interrupted time series analysis was conducted using monthly hand soap usage data from April 2022 to March 2024. The following nudge messages were placed in restrooms: “Are your neighbors washing their hands with soap?” (men) and “Water does not disinfect; soap works!” (women). A generalized least squares model with harmonic terms was used to analyze the data, accounting for seasonality and autocorrelation.

Results

The intervention was associated with an immediate increase of 147.85 units/month in hand soap usage (95% confidence interval [CI]: 61.87–233.83; P = 0.003). However, usage gradually decreased by 11.47 units/month thereafter (95% CI: –27.10 to 4.15; P = 0.166). Sensitivity analysis using Poisson regression confirmed the robustness of these findings. The intervention was associated with a 38.5% increase in hand soap usage (incidence rate ratio [IRR] = 1.385, 95% CI: 1.265–1.515, P < 0.001), but there was a subsequent 1.9% monthly decrease (IRR = 0.981, 95% CI: 0.965–0.997, P = 0.019).

Conclusions

These findings suggest that nudge-based interventions can be effective in promoting hand hygiene in Japanese health-care settings, but the effect may wane over time.

本研究旨在评估日本医院环境中轻推信息对洗手液使用的有效性。方法对2022年4月至2024年3月每月洗手液使用数据进行中断时间序列分析。洗手间里贴着这样的提示信息：“你的邻居用肥皂洗手吗？”（男人）和“水不消毒；soap工作!”(女性)。采用调和项广义最小二乘模型对数据进行分析，考虑了季节性和自相关性。结果干预与立即增加147.85单位/月的洗手液使用量相关（95%可信区间[CI]: 61.87-233.83; P = 0.003）。然而，此后使用量逐渐减少11.47个单位/月（95% CI: -27.10至4.15;P = 0.166）。使用泊松回归的敏感性分析证实了这些发现的稳健性。干预与洗手液使用率增加38.5%相关（发病率比[IRR] = 1.385, 95% CI: 1.265-1.515, P < 0.001），但随后每月下降1.9% （IRR = 0.981, 95% CI: 0.965-0.997, P = 0.019）。这些发现表明，在日本卫生保健机构中，以轻推为基础的干预措施可以有效地促进手卫生，但效果可能会随着时间的推移而减弱。

{"title":"Impact of a nudge-based intervention on hand soap usage in a Japanese Hospital: interrupted time series analysis","authors":"Tetsuji Morishita , Masayoshi Monji , Masao Kuwabara , Shin Lee , Makoto Hayashi , Hisashi Tsurumi , Hidetoshi Matsunami","doi":"10.1016/j.infpip.2025.100494","DOIUrl":"10.1016/j.infpip.2025.100494","url":null,"abstract":"<div><h3>Background</h3><div>This study aimed to evaluate the effectiveness of nudge-based messages on hand soap usage in a Japanese hospital setting.</div></div><div><h3>Methods</h3><div>Interrupted time series analysis was conducted using monthly hand soap usage data from April 2022 to March 2024. The following nudge messages were placed in restrooms: “Are your neighbors washing their hands with soap?” (men) and “Water does not disinfect; soap works!” (women). A generalized least squares model with harmonic terms was used to analyze the data, accounting for seasonality and autocorrelation.</div></div><div><h3>Results</h3><div>The intervention was associated with an immediate increase of 147.85 units/month in hand soap usage (95% confidence interval [CI]: 61.87–233.83; <em>P</em> = 0.003). However, usage gradually decreased by 11.47 units/month thereafter (95% CI: –27.10 to 4.15; <em>P</em> = 0.166). Sensitivity analysis using Poisson regression confirmed the robustness of these findings. The intervention was associated with a 38.5% increase in hand soap usage (incidence rate ratio [IRR] = 1.385, 95% CI: 1.265–1.515, <em>P</em> < 0.001), but there was a subsequent 1.9% monthly decrease (IRR = 0.981, 95% CI: 0.965–0.997, <em>P</em> = 0.019).</div></div><div><h3>Conclusions</h3><div>These findings suggest that nudge-based interventions can be effective in promoting hand hygiene in Japanese health-care settings, but the effect may wane over time.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 4","pages":"Article 100494"},"PeriodicalIF":1.9,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145519494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Implementation of a peripheral intravenous catheter bundle to reduce phlebitis and hospital-onset Staphylococcus aureus bacteremia: A quality improvement project 实施外周静脉导管束以减少静脉炎和院内发生的金黄色葡萄球菌菌血症：一项质量改进项目

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-10-27 DOI: 10.1016/j.infpip.2025.100495

Jie Li , Maria Theresa Cabahug , Tuodi Wu , Hairu Chai , Rongyan An , Nicole Shu Ning Teoh , Liang Fang Yu , Zaleha binte Alias , Shi Yun Foo , Suhailah binte Nasir , Wenyi Seow , Philomena Liew , Thean Yen Tan

Background

Peripheral intravenous catheters (PIVCs) are widely used in hospitals and account for up to one-third of hospital-onset Staphylococcus aureus bacteremia (HO-SAB) cases.

Local Problem

In response to increasing HO-SAB, a quality improvement initiative was launched to reduce PIVC-related phlebitis and HO-SAB.

Methods

An evidence-based bundle for peripheral intravenous catheter (PIVC) insertion and care was developed, focusing on four key components: hand hygiene, aseptic technique during insertion, daily monitoring and timely removal of PIVCs, and optimization of maintenance care. The bundle was piloted in two wards using the Model for Improvement, which led to a reduction in phlebitis rates. The same PIVC bundle was subsequently implemented in a phased manner across the hospital, with the implementation process guided by Kotter's 8-step model of change to ensure effective and sustainable adoption.

Interventions

Interventions involved staff education, daily PIVC checks, process and outcome monitoring with feedback, ongoing ward engagement, and hospital-wide awareness campaigns. Key implementation measures included bundle compliance, phlebitis rates, and PIVC-related HO-SAB.

Results

Phlebitis rates in pilot wards declined from 7% to 1–2%, with comparable reductions observed after hospital-wide implementation. PIVC-related HO-SAB rates decreased from 0.61 (pre-implementation) to 0.26 episodes per 10,000 patient-days.

Conclusions

Overall, the structured care bundle significantly reduced phlebitis and was associated with lower PIVC-related HO-SAB rates.

外周静脉导管（pivc）在医院广泛使用，占医院发病金黄色葡萄球菌菌血症（HO-SAB）病例的三分之一。当地问题为应对越来越多的HO-SAB，开展了一项质量改进倡议，以减少pivc相关的静脉炎和HO-SAB。方法以手卫生、置管过程中的无菌技术、静脉导管的日常监测和及时拔出、维持护理的优化为重点，构建静脉导管置入与护理循证指南。使用改进模式在两个病房进行了捆绑试验，从而降低了静脉炎的发生率。随后在整个医院分阶段实施了相同的PIVC捆绑包，实施过程由Kotter的8步变化模型指导，以确保有效和可持续的采用。干预措施包括员工教育、每日PIVC检查、过程和结果的反馈监测、持续的病房参与以及全医院的意识宣传活动。关键实施措施包括束依从性、静脉炎率和与pivc相关的HO-SAB。结果试点病房的静脉炎率从7%下降到1-2%，在全院范围内实施后也有类似的下降。pivc相关的HO-SAB发生率从0.61例（实施前）降至0.26例/ 10,000患者日。结论：总体而言，结构化护理包显著减少了静脉炎，并与较低的pivc相关HO-SAB发生率相关。

{"title":"Implementation of a peripheral intravenous catheter bundle to reduce phlebitis and hospital-onset Staphylococcus aureus bacteremia: A quality improvement project","authors":"Jie Li , Maria Theresa Cabahug , Tuodi Wu , Hairu Chai , Rongyan An , Nicole Shu Ning Teoh , Liang Fang Yu , Zaleha binte Alias , Shi Yun Foo , Suhailah binte Nasir , Wenyi Seow , Philomena Liew , Thean Yen Tan","doi":"10.1016/j.infpip.2025.100495","DOIUrl":"10.1016/j.infpip.2025.100495","url":null,"abstract":"<div><h3>Background</h3><div>Peripheral intravenous catheters (PIVCs) are widely used in hospitals and account for up to one-third of hospital-onset <em>Staphylococcus aureus</em> bacteremia (HO-SAB) cases.</div></div><div><h3>Local Problem</h3><div>In response to increasing HO-SAB, a quality improvement initiative was launched to reduce PIVC-related phlebitis and HO-SAB.</div></div><div><h3>Methods</h3><div>An evidence-based bundle for peripheral intravenous catheter (PIVC) insertion and care was developed, focusing on four key components: hand hygiene, aseptic technique during insertion, daily monitoring and timely removal of PIVCs, and optimization of maintenance care. The bundle was piloted in two wards using the Model for Improvement, which led to a reduction in phlebitis rates. The same PIVC bundle was subsequently implemented in a phased manner across the hospital, with the implementation process guided by Kotter's 8-step model of change to ensure effective and sustainable adoption.</div></div><div><h3>Interventions</h3><div>Interventions involved staff education, daily PIVC checks, process and outcome monitoring with feedback, ongoing ward engagement, and hospital-wide awareness campaigns. Key implementation measures included bundle compliance, phlebitis rates, and PIVC-related HO-SAB.</div></div><div><h3>Results</h3><div>Phlebitis rates in pilot wards declined from 7% to 1–2%, with comparable reductions observed after hospital-wide implementation. PIVC-related HO-SAB rates decreased from 0.61 (pre-implementation) to 0.26 episodes per 10,000 patient-days.</div></div><div><h3>Conclusions</h3><div>Overall, the structured care bundle significantly reduced phlebitis and was associated with lower PIVC-related HO-SAB rates.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 4","pages":"Article 100495"},"PeriodicalIF":1.9,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145519495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbapenem-Resistant Klebsiella pneumoniae outbreak in the Intensive Care Unit of a cancer centre 耐碳青霉烯肺炎克雷伯菌在癌症中心重症监护病房爆发

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-10-21 DOI: 10.1016/j.infpip.2025.100493

Yuying Pang , Yan Hu , Jiaoyang Zhu , Zhaoxia Liu , Youquan Zhou , Xiumei Yang , Yifan Peng , Min Zhao

Background

We describe an outbreak of carbapenem-resistant Klebsiella pneumoniae (CRKP) nosocomial infection in the intensive care unit (ICU) of a cancer hospital. We evaluate the containment measures implemented and provide evidence-based recommendations for improving CRKP infection prevention and control strategies.

Methods

Between June and July 2023, a comprehensive epidemiological investigation was conducted, including environmental hygiene surveillance and targeted infection control interventions. These measures focused on patients with CRKP nosocomial infections in the ICU, and their effectiveness was systematically evaluated.

Results

A total of 22 CRKP strains were identified in 14 patients(including one transferred from another hospital), with 13 nosocomial infections. Five patients had infections at multiple sites. The nosocomial infection rate was 8.1%, representing a statistically significant increase compared to the same period in previous years. Environmental surveillance detected CRKP contamination on the hands of two doctors (8.7% detection rate) and on various surfaces (8% detection rate), particularly shared equipment, bed unit surfaces, and sanitary ware. Following the implementation of control measures, the spread was effectively contained.

Conclusions

Key factors contributing to transmission likely included delayed identification of infected patients, inadequate enforcement of isolation protocols, and suboptimal environmental cleaning and disinfection. Early detection, strict isolation measures, and thorough environmental cleaning are essential for effective prevention and control of CRKP in the ICU setting.

背景：我们描述了一家癌症医院重症监护病房（ICU）爆发的碳青霉烯耐药肺炎克雷伯菌（CRKP）医院感染。我们对实施的遏制措施进行评估，并为改进CRKP感染预防和控制策略提供循证建议。方法于2023年6 - 7月开展流行病学调查，包括环境卫生监测和有针对性的感染控制措施。这些措施主要针对ICU的CRKP医院感染患者，并对其有效性进行系统评价。结果14例患者（包括1例外院转诊患者）共检出22株CRKP，院内感染13例。5名患者有多处感染。医院感染率为8.1%，与往年同期相比有显著上升。环境监测在两名医生的手上（检出率为8.7%）和各种表面（检出率为8%），特别是共用设备、床单位表面和卫生洁具上检测到CRKP污染。实施防控措施后，疫情传播得到有效遏制。结论导致传播的关键因素可能包括感染患者的识别延迟、隔离方案的执行不力以及环境清洁和消毒不理想。在ICU环境中，早期发现、严格隔离措施和彻底的环境清洁是有效预防和控制CRKP的必要条件。

{"title":"Carbapenem-Resistant Klebsiella pneumoniae outbreak in the Intensive Care Unit of a cancer centre","authors":"Yuying Pang , Yan Hu , Jiaoyang Zhu , Zhaoxia Liu , Youquan Zhou , Xiumei Yang , Yifan Peng , Min Zhao","doi":"10.1016/j.infpip.2025.100493","DOIUrl":"10.1016/j.infpip.2025.100493","url":null,"abstract":"<div><h3>Background</h3><div>We describe an outbreak of carbapenem-resistant <em>Klebsiella pneumoniae</em> (CRKP) nosocomial infection in the intensive care unit (ICU) of a cancer hospital. We evaluate the containment measures implemented and provide evidence-based recommendations for improving CRKP infection prevention and control strategies.</div></div><div><h3>Methods</h3><div>Between June and July 2023, a comprehensive epidemiological investigation was conducted, including environmental hygiene surveillance and targeted infection control interventions. These measures focused on patients with CRKP nosocomial infections in the ICU, and their effectiveness was systematically evaluated.</div></div><div><h3>Results</h3><div>A total of 22 CRKP strains were identified in 14 patients(including one transferred from another hospital), with 13 nosocomial infections. Five patients had infections at multiple sites. The nosocomial infection rate was 8.1%, representing a statistically significant increase compared to the same period in previous years. Environmental surveillance detected CRKP contamination on the hands of two doctors (8.7% detection rate) and on various surfaces (8% detection rate), particularly shared equipment, bed unit surfaces, and sanitary ware. Following the implementation of control measures, the spread was effectively contained.</div></div><div><h3>Conclusions</h3><div>Key factors contributing to transmission likely included delayed identification of infected patients, inadequate enforcement of isolation protocols, and suboptimal environmental cleaning and disinfection. Early detection, strict isolation measures, and thorough environmental cleaning are essential for effective prevention and control of CRKP in the ICU setting.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 4","pages":"Article 100493"},"PeriodicalIF":1.9,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145465944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retrospective cohort study of Gram-negative bacteraemia shows transmission of hypervirulent Klebsiella pneumoniae in a UK Intensive Care Unit during the Covid-19 pandemic 革兰氏阴性菌血症的回顾性队列研究显示，在Covid-19大流行期间，英国重症监护病房中出现了高致病性肺炎克雷伯菌的传播

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-10-20 DOI: 10.1016/j.infpip.2025.100492

Rachel Bousfield , Ruth Kappeler , Sumita Pai , Olly Allen , Kathy Randall , Jacqueline Keane , Stephen Baker

Background

The National incidence of bloodstream infection (BSI) caused by Klebsiella Pneumoniae increased during the Covid-19 pandemic in the United Kingdom, whilst we observed an increase in BSI caused by Gram-negative bacteria in our adult Intensive Care Unit (ICU).

Methods

We audited all Gram-negative bacterial BSIs between 13^th April 2020 and 25^th December 2021 in our ICU. In total, 41 organisms underwent antimicrobial susceptibility testing and genome sequencing. Notable organisms isolated included 16 Klebsiella spp., 4 E. coli, and 4 Pseudomonas spp.

Results

Overall, we observed a low prevalence of multi-drug resistant (MDR) organisms causing BSI on our unit. A fifth (4/20) of E. coli and Klebsiella spp. isolates carried ESBL or AmpC genes and a single P. monteilli carried the IMP-1 gene. At least 3/16 (19%) BSI with Klebsiella spp. were likely associated with transmission between patients in nearby beds. These transmission events were associated with two hypervirulent K. pneumoniae (ST412 and ST86) and a K. aerogenes ∗002b. Half of all K. pneumoniae associated with BSI were hypervirulent, having K2 or K57 capsule type and the presence of iuc, iro, Rmp genes.

Discussion

Hypervirulent K. pneumoniae is an emerging problem, capable of causing a severe, disseminated infection. We suggest risk factors for transmission may include shared equipment, environmental and PPE contamination, and failure of effective hand hygiene. With COVID-19 infection endemic, if SARS-CoV-2 patients require cohort nursing in bays with sessional use gowns, we recommend these are short-sleeved, to facilitate effective hand hygiene. We argue strict Infection Control policy, including enhanced cleaning, is critical to reduce transmission of hypervirulent K. pneumoniae and advocate for enhanced national surveillance systems.

背景：在英国Covid-19大流行期间，由肺炎克雷伯菌引起的全国血液感染（BSI）发生率增加，同时我们观察到成人重症监护病房（ICU）由革兰氏阴性菌引起的BSI发生率增加。方法对2020年4月13日至2021年12月25日ICU中所有革兰氏阴性细菌性脑损伤患者进行审计。共有41种微生物进行了抗菌药敏试验和基因组测序。检出的主要病原菌包括16株克雷伯氏菌、4株大肠杆菌和4株假单胞菌。结果总体而言，我们观察到引起BSI的多重耐药（MDR）病原菌的发生率较低。1 / 5（4/20）的大肠杆菌和克雷伯氏菌分离株携带ESBL或AmpC基因，1株蒙氏杆菌携带IMP-1基因。至少3/16（19%）感染克雷伯氏菌的BSI可能与附近病床患者之间的传播有关。这些传播事件与两种高毒力肺炎克雷伯菌（ST412和ST86）和一种产气克雷伯菌∗002b有关。与BSI相关的所有肺炎克雷伯菌中有一半是高毒力的，具有K2或K57胶囊型，并且存在iuc， iro， Rmp基因。高毒力肺炎克雷伯菌是一个新出现的问题，能够引起严重的播散性感染。我们建议传播的风险因素可能包括共用设备、环境和个人防护用品污染以及没有有效的手部卫生。在COVID-19流行感染的情况下，如果SARS-CoV-2患者需要在穿罩衣的隔间里进行队列护理，我们建议穿短袖罩衣，以促进有效的手部卫生。我们认为严格的感染控制政策，包括加强清洁，对于减少高毒力肺炎克雷伯菌的传播至关重要，并主张加强国家监测系统。

{"title":"Retrospective cohort study of Gram-negative bacteraemia shows transmission of hypervirulent Klebsiella pneumoniae in a UK Intensive Care Unit during the Covid-19 pandemic","authors":"Rachel Bousfield , Ruth Kappeler , Sumita Pai , Olly Allen , Kathy Randall , Jacqueline Keane , Stephen Baker","doi":"10.1016/j.infpip.2025.100492","DOIUrl":"10.1016/j.infpip.2025.100492","url":null,"abstract":"<div><h3>Background</h3><div>The National incidence of bloodstream infection (BSI) caused by <em>Klebsiella Pneumoniae</em> increased during the Covid-19 pandemic in the United Kingdom, whilst we observed an increase in BSI caused by Gram-negative bacteria in our adult Intensive Care Unit (ICU).</div></div><div><h3>Methods</h3><div>We audited all Gram-negative bacterial BSIs between 13<sup>th</sup> April 2020 and 25<sup>th</sup> December 2021 in our ICU. In total, 41 organisms underwent antimicrobial susceptibility testing and genome sequencing. Notable organisms isolated included 16 <em>Klebsiella</em> spp., 4 <em>E. coli</em>, and 4 <em>Pseudomonas</em> spp.</div></div><div><h3>Results</h3><div>Overall, we observed a low prevalence of multi-drug resistant (MDR) organisms causing BSI on our unit. A fifth (4/20) of <em>E. coli</em> and <em>Klebsiella</em> spp. isolates carried ESBL or AmpC genes and a single <em>P. monteilli</em> carried the IMP-1 gene. At least 3/16 (19%) BSI with <em>Klebsiella</em> spp. were likely associated with transmission between patients in nearby beds. These transmission events were associated with two hypervirulent <em>K. pneumoniae</em> (ST412 and ST86) and a <em>K. aerogenes</em> ∗002b. Half of all <em>K. pneumoniae</em> associated with BSI were hypervirulent, having K2 or K57 capsule type and the presence of <em>iuc, iro, Rmp</em> genes.</div></div><div><h3>Discussion</h3><div>Hypervirulent <em>K. pneumoniae</em> is an emerging problem, capable of causing a severe, disseminated infection. We suggest risk factors for transmission may include shared equipment, environmental and PPE contamination, and failure of effective hand hygiene. With COVID-19 infection endemic, if SARS-CoV-2 patients require cohort nursing in bays with sessional use gowns, we recommend these are short-sleeved, to facilitate effective hand hygiene. We argue strict Infection Control policy, including enhanced cleaning, is critical to reduce transmission of hypervirulent <em>K. pneumoniae</em> and advocate for enhanced national surveillance systems.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 4","pages":"Article 100492"},"PeriodicalIF":1.9,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145520123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of infection prevention and antibiotic stewardship programs at a tertiary-care hospital in Southwest Ethiopia: An opportunity to leverage the synergy 埃塞俄比亚西南部一家三级医院的感染预防和抗生素管理方案评估：利用协同作用的机会

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-10-18 DOI: 10.1016/j.infpip.2025.100489

Mulualem Tadesse , Selam Tesfaye , Abebe Dukessa , Belay Zawdie , Birhanu Yenealem , Kisi Chemeda , Addisalem Gebre , Daniel Dana , Henok Gulilat , Tadele Akeba Diriba , Amare Assefa , Diriba Fufa , Gemeda Abebe

Background

Effective infection prevention and control (IPC) and antimicrobial stewardship programs (ASPs) are essential components of hospitals. This study aims to evaluate the status of IPC and ASPs at Jimma University Medical Center (JUMC), a tertiary care hospital, in Southwest Oromia, Ethiopia.

Methods

A facility-based cross-sectional study was conducted in two parts. In part one, data on the core components of IPC were collected using the WHO Infection Prevention and Control Assessment Framework (IPCAF) tool. The hospital's IPC level was determined based on the total scores for the core components. In part two, ASP assessment tool was used to gather data on the core elements of ASPs, and the hospital's ASP status was determined based on the total scores.

Results

The overall IPC scores of JUMC was 455, corresponding to an intermediate level. The highest scores were observed for the IPC program (70), monitoring and feedback of IPC practices (67.5), and multimodal strategies (65). The lowest scores were for hospital-acquired infections (HAIs) surveillance (25) and IPC education and training (50). Regarding ASPs, the overall score was 51.2%, indicating a moderate level of ASP. Significant gaps were found in ASP core elements; education (0%), tracking antibiotic use (27.3%) and hospital leadership commitment (42.9%).

Conclusions

The IPC and ASP programs at JUMC are performing at intermediate and moderate levels, respectively. Attention is required to strengthen HAIs surveillance, tracking of antibiotic uses, and education and training. The overlap between IPC and ASPs presents an opportunity for future collaborative efforts to enhance both programs.

有效的感染预防和控制（IPC）和抗菌药物管理计划（asp）是医院必不可少的组成部分。本研究旨在评估埃塞俄比亚奥罗米亚西南部三级保健医院吉马大学医学中心（JUMC）的IPC和asp状况。方法以设施为基础的横断面研究分为两部分。在第一部分中，使用世卫组织感染预防和控制评估框架（IPCAF）工具收集了IPC核心组成部分的数据。医院的IPC水平是根据核心组件的总分来确定的。第二部分采用ASP评估工具收集ASP核心要素数据，根据总分确定医院ASP状况。结果JUMC的IPC总分为455分，处于中等水平。IPC项目（70分）、IPC实践的监测和反馈（67.5分）和多模式策略（65分）得分最高。得分最低的是医院获得性感染（HAIs）监测（25分）和IPC教育和培训（50分）。在ASP方面，总体得分为51.2%，表明ASP水平中等。ASP核心元素存在显著差异；教育（0%）、抗生素使用跟踪（27.3%）和医院领导承诺（42.9%）。结论JUMC的IPC和ASP程序分别处于中等和中等水平。需要注意加强卫生保健指数的监测、抗生素使用的跟踪以及教育和培训。IPC和asp之间的重叠为未来的合作努力提供了机会，以加强这两个项目。

{"title":"Evaluation of infection prevention and antibiotic stewardship programs at a tertiary-care hospital in Southwest Ethiopia: An opportunity to leverage the synergy","authors":"Mulualem Tadesse , Selam Tesfaye , Abebe Dukessa , Belay Zawdie , Birhanu Yenealem , Kisi Chemeda , Addisalem Gebre , Daniel Dana , Henok Gulilat , Tadele Akeba Diriba , Amare Assefa , Diriba Fufa , Gemeda Abebe","doi":"10.1016/j.infpip.2025.100489","DOIUrl":"10.1016/j.infpip.2025.100489","url":null,"abstract":"<div><h3>Background</h3><div>Effective infection prevention and control (IPC) and antimicrobial stewardship programs (ASPs) are essential components of hospitals. This study aims to evaluate the status of IPC and ASPs at Jimma University Medical Center (JUMC), a tertiary care hospital, in Southwest Oromia, Ethiopia.</div></div><div><h3>Methods</h3><div>A facility-based cross-sectional study was conducted in two parts. In part one, data on the core components of IPC were collected using the WHO Infection Prevention and Control Assessment Framework (IPCAF) tool. The hospital's IPC level was determined based on the total scores for the core components. In part two, ASP assessment tool was used to gather data on the core elements of ASPs, and the hospital's ASP status was determined based on the total scores.</div></div><div><h3>Results</h3><div>The overall IPC scores of JUMC was 455, corresponding to an intermediate level. The highest scores were observed for the IPC program (70), monitoring and feedback of IPC practices (67.5), and multimodal strategies (65). The lowest scores were for hospital-acquired infections (HAIs) surveillance (25) and IPC education and training (50). Regarding ASPs, the overall score was 51.2%, indicating a moderate level of ASP. Significant gaps were found in ASP core elements; education (0%), tracking antibiotic use (27.3%) and hospital leadership commitment (42.9%).</div></div><div><h3>Conclusions</h3><div>The IPC and ASP programs at JUMC are performing at intermediate and moderate levels, respectively. Attention is required to strengthen HAIs surveillance, tracking of antibiotic uses, and education and training. The overlap between IPC and ASPs presents an opportunity for future collaborative efforts to enhance both programs.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 4","pages":"Article 100489"},"PeriodicalIF":1.9,"publicationDate":"2025-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145416747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of smartphone-based monitoring on reducing National Health Service visits for cardiothoracic patients with surgical site infections 基于智能手机的监测对减少手术部位感染的心胸病人的国民健康服务访问的影响

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-10-16 DOI: 10.1016/j.infpip.2025.100491

Melissa Rochon , Angila Jawarchan , Jamie Croker , Anna Thompson , Glorea P. Rajakumar , Nnadiebere Ayogu , Karen Cariaga , Ana Alves , Judith Tanner

Background

Surgical site infections (SSIs) are a leading cause of postoperative morbidity, contributing to significant healthcare resource utilisation and economic burden. This study evaluates the impact of smartphone-based remote monitoring of surgical wounds on reducing healthcare visits for cardiothoracic patients with SSIs within the National Health Service (NHS).

Methods

A retrospective, multi-site service evaluation was conducted at Guy's and St Thomas' NHS Foundation Trust (GSTT), encompassing three specialised cardiac hospitals in London. Adult patients having cardiothoracic surgery were monitored for SSI using the Isla digital platform. SSI rates and associated NHS visits were analysed and compared against national cardiothoracic data.

Results

1,248 patients enrolled onto the Isla wound monitoring platform over a six-month period, showed an SSI rate of 6.7% and an overall response rate to Isla of 88%. 77 patients with an SSI at GSTT used 295 NHS visits, significantly fewer healthcare resources across nearly all visit types compared to national cardiothoracic SSI patients, including general practitioner (GP), nurse, outpatient and Accident and Emergency attendances (P< 0.05). The only exception was readmissions for SSIs that developed after hospital discharge, where there was no significant difference between GSTT and national patients (P = 0.9197). The median wound healing time for patients with digital monitoring was 19 days (range 2–156 days), while the national data reports a mean time to heal of 91.7 days ±67.5.

Conclusion

Smartphone-based remote wound monitoring significantly reduced healthcare visits while maintaining effective SSI management, aligning with NHS objectives to enhance resource efficiency and patient convenience. These findings underscore the potential of remote monitoring in postoperative care and warrant further studies to assess its broader applicability.

背景：手术部位感染（ssi）是术后发病率的主要原因，造成了巨大的医疗资源利用和经济负担。本研究评估了基于智能手机的手术伤口远程监测对减少国家卫生服务（NHS）心胸外科ssi患者就诊的影响。方法回顾性、多站点服务评估在盖伊和圣托马斯NHS基金会信托（GSTT）进行，包括伦敦的三家专业心脏医院。使用Isla数字平台监测接受心胸外科手术的成年患者的SSI。分析了SSI发生率和相关的NHS就诊情况，并与全国心胸数据进行了比较。结果1248例患者在6个月的时间内进入Isla伤口监测平台，SSI率为6.7%，Isla的总有效率为88%。GSTT的77例SSI患者使用了295次NHS就诊，与全国心胸SSI患者相比，几乎所有就诊类型的医疗保健资源都明显减少，包括全科医生（GP）、护士、门诊和急症护理（P< 0.05）。唯一的例外是出院后发生的ssi再入院，GSTT与本国患者之间无显著差异（P = 0.9197）。数字监测患者的中位伤口愈合时间为19天（范围2-156天），而国家数据报告的平均愈合时间为91.7天±67.5天。结论基于智能手机的伤口远程监测可显著减少就医次数，同时保持有效的伤口损伤管理，符合NHS的目标，提高资源效率和患者便利性。这些发现强调了远程监测在术后护理中的潜力，值得进一步研究以评估其更广泛的适用性。

{"title":"The impact of smartphone-based monitoring on reducing National Health Service visits for cardiothoracic patients with surgical site infections","authors":"Melissa Rochon , Angila Jawarchan , Jamie Croker , Anna Thompson , Glorea P. Rajakumar , Nnadiebere Ayogu , Karen Cariaga , Ana Alves , Judith Tanner","doi":"10.1016/j.infpip.2025.100491","DOIUrl":"10.1016/j.infpip.2025.100491","url":null,"abstract":"<div><h3>Background</h3><div>Surgical site infections (SSIs) are a leading cause of postoperative morbidity, contributing to significant healthcare resource utilisation and economic burden. This study evaluates the impact of smartphone-based remote monitoring of surgical wounds on reducing healthcare visits for cardiothoracic patients with SSIs within the National Health Service (NHS).</div></div><div><h3>Methods</h3><div>A retrospective, multi-site service evaluation was conducted at Guy's and St Thomas' NHS Foundation Trust (GSTT), encompassing three specialised cardiac hospitals in London. Adult patients having cardiothoracic surgery were monitored for SSI using the Isla digital platform. SSI rates and associated NHS visits were analysed and compared against national cardiothoracic data.</div></div><div><h3>Results</h3><div>1,248 patients enrolled onto the Isla wound monitoring platform over a six-month period, showed an SSI rate of 6.7% and an overall response rate to Isla of 88%. 77 patients with an SSI at GSTT used 295 NHS visits, significantly fewer healthcare resources across nearly all visit types compared to national cardiothoracic SSI patients, including general practitioner (GP), nurse, outpatient and Accident and Emergency attendances (<em>P</em>< 0.05). The only exception was readmissions for SSIs that developed after hospital discharge, where there was no significant difference between GSTT and national patients (<em>P</em> = 0.9197). The median wound healing time for patients with digital monitoring was 19 days (range 2–156 days), while the national data reports a mean time to heal of 91.7 days ±67.5.</div></div><div><h3>Conclusion</h3><div>Smartphone-based remote wound monitoring significantly reduced healthcare visits while maintaining effective SSI management, aligning with NHS objectives to enhance resource efficiency and patient convenience. These findings underscore the potential of remote monitoring in postoperative care and warrant further studies to assess its broader applicability.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 4","pages":"Article 100491"},"PeriodicalIF":1.9,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145416748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Delhi metallo-β-lactamase-1 -producing Klebsiella oxytoca sequence type 2 from toilets as the likely source of nosocomial transmission to patients – a root cause analysis 从厕所中发现的产生金属β-内酰胺酶1的克雷伯菌2型产氧序列可能是医院传播给患者的来源——根本原因分析

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-10-09 DOI: 10.1016/j.infpip.2025.100487

H.D. Eriksen , L.J. Porsbo , B. Bang , N. Ank , H. Hasman

Background

The hospital environment is a known reservoir for nosocomial infections, with bathroom plumbing increasingly implicated in the spread of carbapenemase-producing Enterobacterales (CPE). At Aalborg University Hospital (AUH), Denmark, two ongoing outbreaks of CPE have been linked to Citrobacter freundii sequence type 18 (ST18) and Klebsiella oxytoca ST2. While both outbreak strains carry a bla_NDM-1 gene on distinct plasmids, the role of bathroom fixtures in their transmission to patients remains unclear.

Aim

This study aims to investigate the environmental reservoirs and potential transmission routes of New Delhi metallo-β-lactamase-1 (NDM-1)-producing K. oxytoca isolates associated with patients and the environment within the Gastric Surgery Unit (GSU) at AUH.

Methods

Weekly rectal swabs were conducted on GSU patients, accompanied by environmental sampling at two timepoints of toilets, drains, and dry surfaces over a 450-day period. Whole-genome sequencing and plasmid analysis were used to assess genetic relationships between environmental and patient isolates. Additional targeted environmental screenings focused on bathrooms in high-risk rooms.

Findings

NDM-1-producing K. oxytoca ST2 was consistently detected in three toilets, each harbouring distinct genomic sub-clades. Four patients were later found colonized with isolates genetically related to those from the toilets. No evidence of direct patient-to-patient transmission was found, underscoring the role of toilets as reservoirs in the outbreak.

Conclusion

Temporal data relating to the various samples suggest that the environmental reservoirs in two specific bathrooms, and presumably their toilets, are the most likely sources of transmission to the four patients at the GSU.

医院环境是已知的医院感染的储库，浴室管道越来越多地与产碳青霉烯酶肠杆菌（CPE）的传播有关。在丹麦奥尔堡大学医院（AUH），正在发生的两起CPE暴发与弗氏Citrobacter freundii序列18型（ST18）和克雷伯菌oxytoca ST2有关。虽然这两种爆发菌株在不同的质粒上携带blaNDM-1基因，但浴室装置在它们传播给患者中的作用仍不清楚。目的探讨新德里金属β-内酰胺酶-1 （NDM-1）产氧梭菌（k.o oxytoca）分离株与AUH胃外科（GSU）患者和环境相关的环境宿主和潜在传播途径。方法每周对GSU患者进行直肠拭子取样，并在厕所、排水沟和干燥表面两个时间点进行环境采样，为期450天。全基因组测序和质粒分析用于评估环境和患者分离株之间的遗传关系。额外的有针对性的环境筛查集中在高危房间的浴室。在三个厕所中一致检测到产生sndm -1的K. oxytoca ST2，每个厕所都有不同的基因组亚枝。后来发现，四名患者身上有与厕所感染的病毒基因相关的分离株。没有发现患者之间直接传播的证据，这强调了厕所在疫情中作为宿主的作用。结论与各种样本相关的时间数据表明，两个特定浴室的环境水库（可能是他们的厕所）是GSU四名患者最有可能的传播源。

{"title":"New Delhi metallo-β-lactamase-1 -producing Klebsiella oxytoca sequence type 2 from toilets as the likely source of nosocomial transmission to patients – a root cause analysis","authors":"H.D. Eriksen , L.J. Porsbo , B. Bang , N. Ank , H. Hasman","doi":"10.1016/j.infpip.2025.100487","DOIUrl":"10.1016/j.infpip.2025.100487","url":null,"abstract":"<div><h3>Background</h3><div>The hospital environment is a known reservoir for nosocomial infections, with bathroom plumbing increasingly implicated in the spread of carbapenemase-producing Enterobacterales (CPE). At Aalborg University Hospital (AUH), Denmark, two ongoing outbreaks of CPE have been linked to <em>Citrobacter freundii</em> sequence type 18 (ST18) and <em>Klebsiella oxytoca</em> ST2. While both outbreak strains carry a <em>bla</em><sub>NDM-1</sub> gene on distinct plasmids, the role of bathroom fixtures in their transmission to patients remains unclear.</div></div><div><h3>Aim</h3><div>This study aims to investigate the environmental reservoirs and potential transmission routes of New Delhi metallo-β-lactamase-1 (NDM-1)-producing <em>K. oxytoca</em> isolates associated with patients and the environment within the Gastric Surgery Unit (GSU) at AUH.</div></div><div><h3>Methods</h3><div>Weekly rectal swabs were conducted on GSU patients, accompanied by environmental sampling at two timepoints of toilets, drains, and dry surfaces over a 450-day period. Whole-genome sequencing and plasmid analysis were used to assess genetic relationships between environmental and patient isolates. Additional targeted environmental screenings focused on bathrooms in high-risk rooms.</div></div><div><h3>Findings</h3><div>NDM-1-producing <em>K. oxytoca</em> ST2 was consistently detected in three toilets, each harbouring distinct genomic sub-clades. Four patients were later found colonized with isolates genetically related to those from the toilets. No evidence of direct patient-to-patient transmission was found, underscoring the role of toilets as reservoirs in the outbreak.</div></div><div><h3>Conclusion</h3><div>Temporal data relating to the various samples suggest that the environmental reservoirs in two specific bathrooms, and presumably their toilets, are the most likely sources of transmission to the four patients at the GSU.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 4","pages":"Article 100487"},"PeriodicalIF":1.9,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145362943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Implementation and evaluation of infection prevention and control training in sub-Saharan Africa 撒哈拉以南非洲感染预防和控制培训的实施和评价

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-10-04 DOI: 10.1016/j.infpip.2025.100485

D. Odada , J. Ndai , R. Thuku , R. Adam

Healthcare-associated infections remain a global concern, exacerbated by limited competent infection prevention and control personnel in low- and middle-income countries (LMICs). This study evaluated infection prevention and control training using Kirkpatrick's model to determine its effectiveness in enhancing competence in infection preventionists in Kenya. This descriptive design assessed participants' knowledge and satisfaction with a training workshop through pre- and post-tests and a five-point Likert scale. Forty participants showed significant improvement in knowledge (pre-test: 49%, post-test: 64%; P<0.05) and high satisfaction with the training workshop (mean 4.68/5). The findings affirm the effectiveness of structured training in LMICs to enhance competency, and underscore the need for formal professional development.

医疗保健相关感染仍然是一个全球性问题，低收入和中等收入国家有能力的感染预防和控制人员有限，加剧了这一问题。本研究使用Kirkpatrick模型评估了感染预防和控制培训，以确定其在提高肯尼亚感染预防人员能力方面的有效性。该描述性设计通过前后测试和五点李克特量表评估参与者对培训研讨会的知识和满意度。40名参与者在知识方面有显著提高（前测49%，后测64%；p&t;0.05），对培训车间的满意度较高（平均4.68/5）。研究结果肯定了在中低收入国家进行结构化培训以提高能力的有效性，并强调了正式专业发展的必要性。

引用次数: 0

Minimising the duration of N95 respirator use during hospital SARS-CoV-2 outbreaks: A mixed-effects analysis of post-screening infection reduction 医院SARS-CoV-2暴发期间尽量减少N95口罩的使用时间：筛查后减少感染的混合效应分析

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-09-08 DOI: 10.1016/j.infpip.2025.100484

Mari Yanaka , Toshibumi Taniguchi , Misuzu Yahaba , Shota Murata , Hiroshi Yoshikawa , Hitoshi Chiba , Misao Urushihara , Hidetoshi Igari

Hospital SARS-CoV-2 outbreaks require effective interventions. We evaluated targeted universal N95 respirator use among staff from outbreak identification until screening results. Analysing 18 cluster outbreaks using generalised linear mixed models, we found that N95 respirator use was associated with a 72% reduction in new infections (P<0.001) compared to surgical masks. The mean duration of N95 respirator use was 5.25 days. Policy effectiveness was independent of outbreak size. Bootstrap analysis confirmed significant reduction (mean difference -3.02 cases, 95% CI: -5.98 to -0.08). Infection source showed substantial variability while ward-level variation was minimal. Short-term targeted N95 respirator use effectively controls hospital outbreaks while optimising resources and staff comfort.

医院SARS-CoV-2爆发需要有效的干预措施。我们评估了从疫情识别到筛查结果的工作人员中有针对性的通用N95口罩使用情况。使用广义线性混合模型分析了18起聚集性疫情，我们发现与外科口罩相比，N95呼吸器的使用与新感染减少72%相关（P<0.001）。N95口罩的平均使用时间为5.25 d。政策有效性与爆发规模无关。Bootstrap分析证实显著减少（平均差异为-3.02例，95% CI: -5.98至-0.08）。感染源有很大的差异，而病区差异很小。短期有针对性地使用N95口罩，有效控制医院疫情，同时优化资源和员工舒适度。

引用次数: 0