Infection Prevention in Practice最新文献_第4页

Impact of the COVID-19 pandemic on alcohol-based hand rub consumption and hand hygiene compliance: a cross-sectional study using digital direct-observation tools in Slovakia COVID-19大流行对酒精洗手液消费和手部卫生合规的影响：在斯洛伐克使用数字直接观察工具进行的横断面研究

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-12-01 Epub Date: 2025-08-14 DOI: 10.1016/j.infpip.2025.100481

Chebenová Vanesa , Bučková Veronika , Škvarková Zuzana , Balintová Natália , Sokolová Jaroslava

Background

Hand hygiene (HH) among healthcare professionals (HCPs) is a key component in ensuring safe and high-quality healthcare. Monitoring the Five moments for HH according to World Health Organization (WHO) guidelines remains the gold standard for compliance assessment. Proper HH is the most effective measure to prevent healthcare-associated infections (HAI).

Aim

This cross-sectional study aimed to quantify HH compliance and alcohol-based hand rub (ABHR) consumption among HCPS at the University Hospital Trnava in Slovakia and to compare results between the pre-pandemic and post-pandemic periods.

Methods

HH compliance was monitored during the pre-pandemic period (2018–2019) and the post-pandemic period (2022–2023). Compliance was assessed among different groups of HCPs – physicians, nurses and other healthcare personnel (e.g., physiotherapists, orderlies and students). Monitoring was conducted using WHO methodology and recorded via the OBSERVE app.

Findings

During the pre-pandemic period, overall HH compliance was 50.2% (95% CI, 48.7.-51.8), with nurses demonstrating the highest compliance rate. In the post-pandemic period, HH compliance remained nearly unchanged at (50.8%; 95% CI, 48.9–52.7). ABHR consumption increased significantly during the COVID-19 pandemic, peaking at 48.4 litres/1 000 patient days (PD), but declined to 31.5 litres/1 000 PD by 2023.

Conclusion

The COVID-19 pandemic positively influenced ABHR consumption and raised awareness of the importance of HH in clinical practice. However, overall HH compliance did not improve post-pandemic. Direct observation supported by a digital application proved to be an effective method for collecting HH compliance data.

卫生保健专业人员（HCPs）的手部卫生（HH）是确保安全和高质量卫生保健的关键组成部分。根据世界卫生组织（世卫组织）准则监测健康的五个时刻仍然是合规评估的黄金标准。适当的卫生保健是预防卫生保健相关感染（HAI）的最有效措施。目的本横断面研究旨在量化斯洛伐克特尔纳瓦大学医院HCPS的HH依从性和酒精基洗手液（ABHR）消费量，并比较大流行前和大流行后时期的结果。方法在大流行前（2018-2019年）和大流行后（2022-2023年）监测shh的依从性。对不同组的HCPs——医生、护士和其他保健人员（如物理治疗师、护理员和学生）的依从性进行了评估。使用世卫组织方法进行监测，并通过OBSERVE应用程序进行记录。发现在大流行前，总体卫生保健依从率为50.2% (95% CI, 48.7 -51.8)，护士的依从率最高。在大流行后时期，HH依从性几乎保持不变（50.8%;95% CI, 48.9-52.7）。在2019冠状病毒病大流行期间，ABHR消费量显著增加，峰值为48.4升/ 1000患者日（PD），但到2023年降至31.5升/ 1000患者日。结论新冠肺炎疫情对ABHR消费产生了积极影响，提高了人们对HH在临床中的重要性的认识。然而，大流行后，总体HH依从性并未改善。由数字应用程序支持的直接观察被证明是收集HH遵从性数据的有效方法。

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引用次数: 0

Evaluation of infection prevention and antibiotic stewardship programs at a tertiary-care hospital in Southwest Ethiopia: An opportunity to leverage the synergy 埃塞俄比亚西南部一家三级医院的感染预防和抗生素管理方案评估：利用协同作用的机会

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-12-01 Epub Date: 2025-10-18 DOI: 10.1016/j.infpip.2025.100489

Mulualem Tadesse , Selam Tesfaye , Abebe Dukessa , Belay Zawdie , Birhanu Yenealem , Kisi Chemeda , Addisalem Gebre , Daniel Dana , Henok Gulilat , Tadele Akeba Diriba , Amare Assefa , Diriba Fufa , Gemeda Abebe

Background

Effective infection prevention and control (IPC) and antimicrobial stewardship programs (ASPs) are essential components of hospitals. This study aims to evaluate the status of IPC and ASPs at Jimma University Medical Center (JUMC), a tertiary care hospital, in Southwest Oromia, Ethiopia.

Methods

A facility-based cross-sectional study was conducted in two parts. In part one, data on the core components of IPC were collected using the WHO Infection Prevention and Control Assessment Framework (IPCAF) tool. The hospital's IPC level was determined based on the total scores for the core components. In part two, ASP assessment tool was used to gather data on the core elements of ASPs, and the hospital's ASP status was determined based on the total scores.

Results

The overall IPC scores of JUMC was 455, corresponding to an intermediate level. The highest scores were observed for the IPC program (70), monitoring and feedback of IPC practices (67.5), and multimodal strategies (65). The lowest scores were for hospital-acquired infections (HAIs) surveillance (25) and IPC education and training (50). Regarding ASPs, the overall score was 51.2%, indicating a moderate level of ASP. Significant gaps were found in ASP core elements; education (0%), tracking antibiotic use (27.3%) and hospital leadership commitment (42.9%).

Conclusions

The IPC and ASP programs at JUMC are performing at intermediate and moderate levels, respectively. Attention is required to strengthen HAIs surveillance, tracking of antibiotic uses, and education and training. The overlap between IPC and ASPs presents an opportunity for future collaborative efforts to enhance both programs.

有效的感染预防和控制（IPC）和抗菌药物管理计划（asp）是医院必不可少的组成部分。本研究旨在评估埃塞俄比亚奥罗米亚西南部三级保健医院吉马大学医学中心（JUMC）的IPC和asp状况。方法以设施为基础的横断面研究分为两部分。在第一部分中，使用世卫组织感染预防和控制评估框架（IPCAF）工具收集了IPC核心组成部分的数据。医院的IPC水平是根据核心组件的总分来确定的。第二部分采用ASP评估工具收集ASP核心要素数据，根据总分确定医院ASP状况。结果JUMC的IPC总分为455分，处于中等水平。IPC项目（70分）、IPC实践的监测和反馈（67.5分）和多模式策略（65分）得分最高。得分最低的是医院获得性感染（HAIs）监测（25分）和IPC教育和培训（50分）。在ASP方面，总体得分为51.2%，表明ASP水平中等。ASP核心元素存在显著差异；教育（0%）、抗生素使用跟踪（27.3%）和医院领导承诺（42.9%）。结论JUMC的IPC和ASP程序分别处于中等和中等水平。需要注意加强卫生保健指数的监测、抗生素使用的跟踪以及教育和培训。IPC和asp之间的重叠为未来的合作努力提供了机会，以加强这两个项目。

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引用次数: 0

The impact of smartphone-based monitoring on reducing National Health Service visits for cardiothoracic patients with surgical site infections 基于智能手机的监测对减少手术部位感染的心胸病人的国民健康服务访问的影响

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-12-01 Epub Date: 2025-10-16 DOI: 10.1016/j.infpip.2025.100491

Melissa Rochon , Angila Jawarchan , Jamie Croker , Anna Thompson , Glorea P. Rajakumar , Nnadiebere Ayogu , Karen Cariaga , Ana Alves , Judith Tanner

Background

Surgical site infections (SSIs) are a leading cause of postoperative morbidity, contributing to significant healthcare resource utilisation and economic burden. This study evaluates the impact of smartphone-based remote monitoring of surgical wounds on reducing healthcare visits for cardiothoracic patients with SSIs within the National Health Service (NHS).

Methods

A retrospective, multi-site service evaluation was conducted at Guy's and St Thomas' NHS Foundation Trust (GSTT), encompassing three specialised cardiac hospitals in London. Adult patients having cardiothoracic surgery were monitored for SSI using the Isla digital platform. SSI rates and associated NHS visits were analysed and compared against national cardiothoracic data.

Results

1,248 patients enrolled onto the Isla wound monitoring platform over a six-month period, showed an SSI rate of 6.7% and an overall response rate to Isla of 88%. 77 patients with an SSI at GSTT used 295 NHS visits, significantly fewer healthcare resources across nearly all visit types compared to national cardiothoracic SSI patients, including general practitioner (GP), nurse, outpatient and Accident and Emergency attendances (P< 0.05). The only exception was readmissions for SSIs that developed after hospital discharge, where there was no significant difference between GSTT and national patients (P = 0.9197). The median wound healing time for patients with digital monitoring was 19 days (range 2–156 days), while the national data reports a mean time to heal of 91.7 days ±67.5.

Conclusion

Smartphone-based remote wound monitoring significantly reduced healthcare visits while maintaining effective SSI management, aligning with NHS objectives to enhance resource efficiency and patient convenience. These findings underscore the potential of remote monitoring in postoperative care and warrant further studies to assess its broader applicability.

背景：手术部位感染（ssi）是术后发病率的主要原因，造成了巨大的医疗资源利用和经济负担。本研究评估了基于智能手机的手术伤口远程监测对减少国家卫生服务（NHS）心胸外科ssi患者就诊的影响。方法回顾性、多站点服务评估在盖伊和圣托马斯NHS基金会信托（GSTT）进行，包括伦敦的三家专业心脏医院。使用Isla数字平台监测接受心胸外科手术的成年患者的SSI。分析了SSI发生率和相关的NHS就诊情况，并与全国心胸数据进行了比较。结果1248例患者在6个月的时间内进入Isla伤口监测平台，SSI率为6.7%，Isla的总有效率为88%。GSTT的77例SSI患者使用了295次NHS就诊，与全国心胸SSI患者相比，几乎所有就诊类型的医疗保健资源都明显减少，包括全科医生（GP）、护士、门诊和急症护理（P< 0.05）。唯一的例外是出院后发生的ssi再入院，GSTT与本国患者之间无显著差异（P = 0.9197）。数字监测患者的中位伤口愈合时间为19天（范围2-156天），而国家数据报告的平均愈合时间为91.7天±67.5天。结论基于智能手机的伤口远程监测可显著减少就医次数，同时保持有效的伤口损伤管理，符合NHS的目标，提高资源效率和患者便利性。这些发现强调了远程监测在术后护理中的潜力，值得进一步研究以评估其更广泛的适用性。

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引用次数: 0

Retrospective cohort study of Gram-negative bacteraemia shows transmission of hypervirulent Klebsiella pneumoniae in a UK Intensive Care Unit during the Covid-19 pandemic 革兰氏阴性菌血症的回顾性队列研究显示，在Covid-19大流行期间，英国重症监护病房中出现了高致病性肺炎克雷伯菌的传播

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-12-01 Epub Date: 2025-10-20 DOI: 10.1016/j.infpip.2025.100492

Rachel Bousfield , Ruth Kappeler , Sumita Pai , Olly Allen , Kathy Randall , Jacqueline Keane , Stephen Baker

Background

The National incidence of bloodstream infection (BSI) caused by Klebsiella Pneumoniae increased during the Covid-19 pandemic in the United Kingdom, whilst we observed an increase in BSI caused by Gram-negative bacteria in our adult Intensive Care Unit (ICU).

Methods

We audited all Gram-negative bacterial BSIs between 13^th April 2020 and 25^th December 2021 in our ICU. In total, 41 organisms underwent antimicrobial susceptibility testing and genome sequencing. Notable organisms isolated included 16 Klebsiella spp., 4 E. coli, and 4 Pseudomonas spp.

Results

Overall, we observed a low prevalence of multi-drug resistant (MDR) organisms causing BSI on our unit. A fifth (4/20) of E. coli and Klebsiella spp. isolates carried ESBL or AmpC genes and a single P. monteilli carried the IMP-1 gene. At least 3/16 (19%) BSI with Klebsiella spp. were likely associated with transmission between patients in nearby beds. These transmission events were associated with two hypervirulent K. pneumoniae (ST412 and ST86) and a K. aerogenes ∗002b. Half of all K. pneumoniae associated with BSI were hypervirulent, having K2 or K57 capsule type and the presence of iuc, iro, Rmp genes.

Discussion

Hypervirulent K. pneumoniae is an emerging problem, capable of causing a severe, disseminated infection. We suggest risk factors for transmission may include shared equipment, environmental and PPE contamination, and failure of effective hand hygiene. With COVID-19 infection endemic, if SARS-CoV-2 patients require cohort nursing in bays with sessional use gowns, we recommend these are short-sleeved, to facilitate effective hand hygiene. We argue strict Infection Control policy, including enhanced cleaning, is critical to reduce transmission of hypervirulent K. pneumoniae and advocate for enhanced national surveillance systems.

背景：在英国Covid-19大流行期间，由肺炎克雷伯菌引起的全国血液感染（BSI）发生率增加，同时我们观察到成人重症监护病房（ICU）由革兰氏阴性菌引起的BSI发生率增加。方法对2020年4月13日至2021年12月25日ICU中所有革兰氏阴性细菌性脑损伤患者进行审计。共有41种微生物进行了抗菌药敏试验和基因组测序。检出的主要病原菌包括16株克雷伯氏菌、4株大肠杆菌和4株假单胞菌。结果总体而言，我们观察到引起BSI的多重耐药（MDR）病原菌的发生率较低。1 / 5（4/20）的大肠杆菌和克雷伯氏菌分离株携带ESBL或AmpC基因，1株蒙氏杆菌携带IMP-1基因。至少3/16（19%）感染克雷伯氏菌的BSI可能与附近病床患者之间的传播有关。这些传播事件与两种高毒力肺炎克雷伯菌（ST412和ST86）和一种产气克雷伯菌∗002b有关。与BSI相关的所有肺炎克雷伯菌中有一半是高毒力的，具有K2或K57胶囊型，并且存在iuc， iro， Rmp基因。高毒力肺炎克雷伯菌是一个新出现的问题，能够引起严重的播散性感染。我们建议传播的风险因素可能包括共用设备、环境和个人防护用品污染以及没有有效的手部卫生。在COVID-19流行感染的情况下，如果SARS-CoV-2患者需要在穿罩衣的隔间里进行队列护理，我们建议穿短袖罩衣，以促进有效的手部卫生。我们认为严格的感染控制政策，包括加强清洁，对于减少高毒力肺炎克雷伯菌的传播至关重要，并主张加强国家监测系统。

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引用次数: 0

Implementation and evaluation of infection prevention and control training in sub-Saharan Africa 撒哈拉以南非洲感染预防和控制培训的实施和评价

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-12-01 Epub Date: 2025-10-04 DOI: 10.1016/j.infpip.2025.100485

D. Odada , J. Ndai , R. Thuku , R. Adam

Healthcare-associated infections remain a global concern, exacerbated by limited competent infection prevention and control personnel in low- and middle-income countries (LMICs). This study evaluated infection prevention and control training using Kirkpatrick's model to determine its effectiveness in enhancing competence in infection preventionists in Kenya. This descriptive design assessed participants' knowledge and satisfaction with a training workshop through pre- and post-tests and a five-point Likert scale. Forty participants showed significant improvement in knowledge (pre-test: 49%, post-test: 64%; P<0.05) and high satisfaction with the training workshop (mean 4.68/5). The findings affirm the effectiveness of structured training in LMICs to enhance competency, and underscore the need for formal professional development.

医疗保健相关感染仍然是一个全球性问题，低收入和中等收入国家有能力的感染预防和控制人员有限，加剧了这一问题。本研究使用Kirkpatrick模型评估了感染预防和控制培训，以确定其在提高肯尼亚感染预防人员能力方面的有效性。该描述性设计通过前后测试和五点李克特量表评估参与者对培训研讨会的知识和满意度。40名参与者在知识方面有显著提高（前测49%，后测64%；p&t;0.05），对培训车间的满意度较高（平均4.68/5）。研究结果肯定了在中低收入国家进行结构化培训以提高能力的有效性，并强调了正式专业发展的必要性。

引用次数: 0

A decade of epidemiology and incidence of carbapenemase-producing bacteria in a tertiary hospital in southern Europe 欧洲南部某三级医院碳青霉烯酶产菌的流行病学和发病率研究

IF 1.8 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-09-01 Epub Date: 2025-07-03 DOI: 10.1016/j.infpip.2025.100469

I. González-Gómez , G. Ruíz-Carrascoso , R. Herruzo-Cabrera

Background

Carbapenemase-producing Enterobacterales (CPE) are a growing issue that healthcare systems all over the world are facing and which have been producing clinical cases for >20 years, with a spike in incidence in the last decade. In the Universitary Hospital of La Paz (HULP), the first CPE outbreak occurred in 2011 and incidence has been variable since then.

Aim

To conduct an epidemiological analysis of the distribution and microbiological characteristics of the four main types of carbapenemases (OXA-48, VIM, KPC, and NDM) obtained from bacteria isolated in the HULP, a tertiary hospital north of the city of Madrid, between 2012 and 2022.

Methods

An observational retrospective analysis was performed to attain the incidence characteristics of CPE and their associated outbreaks. The study used data from 5723 individual cases for which the sex and age of the patient, type of sample, isolated bacteria, type of carbapenemase, type of case (infection or colonization) and where and when the isolate was obtained.

Results

Since the first outbreak of CPE was detected in 2011, contain-and-response protocols were put in place to avoid the spread of CPE within the hospital setting.

Conclusion

The implementation of CPE infection preventention and control guidance since 2013 and (in 2022) updated protocols has impacted the number of cases, but further incidence studies should be conducted to analyse the effectiveness of these measures and assess the patterns of carbapenemase genes over time.

产碳青霉烯酶肠杆菌（CPE）是世界各地卫生保健系统面临的一个日益严重的问题，并且已经产生了20年的临床病例，在过去十年中发病率激增。在拉巴斯大学医院（HULP），第一次CPE暴发发生在2011年，此后发病率一直在变化。目的对2012年至2022年在马德里市北部的一家三级医院HULP分离的细菌中获得的四种主要类型碳青霉烯酶（OXA-48、VIM、KPC和NDM）的分布和微生物学特征进行流行病学分析。方法采用观察性回顾性分析，了解CPE的发病特点及其相关暴发。该研究使用了来自5723例个体病例的数据，其中包括患者的性别和年龄、样本类型、分离的细菌、碳青霉烯酶类型、病例类型（感染或定植）以及获得分离物的地点和时间。结果自2011年首次发现CPE暴发以来，制定了控制和应对方案，以避免CPE在医院环境中传播。结论自2013年以来实施的CPE感染防控指南和（2022年）更新的方案对病例数量产生了影响，但应开展进一步的发病率研究，以分析这些措施的有效性，并评估碳青霉烯酶基因随时间的变化模式。

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引用次数: 0

The role of vaccination and healthcare acquisition in respiratory failure during a COVID-19 outbreak in an acute hospital in Wales 在威尔士一家急性医院COVID-19爆发期间，疫苗接种和获得医疗保健在呼吸衰竭中的作用

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-09-01 Epub Date: 2025-07-09 DOI: 10.1016/j.infpip.2025.100474

Craig Hogg , Caoimhe McKerr , Noel Craine , Dafydd Williams , Malorie Perry , Simon Cottrell

This study provides descriptive analysis of a COVID-19 outbreak of 323 cases in a Welsh hospital in early 2021, with a focus on respiratory failure (RF) as a severe outcome. Multivariate analysis demonstrated decreased odds of RF in healthcare acquired cases (aOR 0.40 (95%CI 0.24–0.65), p<0.001) and individuals with at least one dose of vaccine 14 days before first positive test (aOR 0.45 (95%CI 0.28–0.75), p=0.002). In healthcare acquired cases, vaccination significantly reduced the odds of RF (OR 0.47 (95%CI 0.22-0.00), p=0.037). This analysis highlights the importance of vaccination as a protective factor against severe respiratory outcomes.

本研究对2021年初威尔士一家医院爆发的323例COVID-19病例进行了描述性分析，重点关注呼吸衰竭（RF）这一严重后果。多因素分析显示，医疗保健获得性病例（aOR 0.40 (95%CI 0.24-0.65), p<0.001）和在首次阳性检测前14天至少接种过一剂疫苗的个体（aOR 0.45 (95%CI 0.28-0.75), p=0.002）发生RF的几率降低。在医疗保健获得性病例中，接种疫苗显著降低了RF的几率（OR 0.47 (95%CI 0.22-0.00), p=0.037）。这一分析强调了疫苗接种作为预防严重呼吸道后果的保护因素的重要性。

引用次数: 0

Antiviral effect of 222 nm far-UVC light against human coronavirus and rhinovirus, and murine norovirus using dried inocula 222 nm远紫外线光对人冠状病毒、鼻病毒及鼠诺如病毒的抗病毒作用

IF 1.8 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-09-01 Epub Date: 2025-06-14 DOI: 10.1016/j.infpip.2025.100473

Ana C. Lorenzo-Leal, Donald Tam, Horacio Bach

引用次数: 0

COVID-19 vaccination and use of antibiotics in COVID-19 patients: a systematic review and meta-analysis COVID-19患者的COVID-19疫苗接种和抗生素使用：系统回顾和荟萃分析

IF 1.9 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-09-01 Epub Date: 2025-06-03 DOI: 10.1016/j.infpip.2025.100461

Marios Politis , Ioanna Chatzichristodoulou , Varvara A. Mouchtouri , Georgios Rachiotis

Background

Vaccinations are considered one of the most effective medical interventions. Among other benefits, certain vaccinations help reduce antimicrobial resistance by decreasing antibiotic use. Considering reports of increased antimicrobial resistance during the COVID-19 pandemic, this study aimed to explore the relationship between COVID-19 vaccination status and antibiotic use in COVID-19 patients.

Methods

A systematic literature search was conducted in PubMed, Scopus, Web of Science, Embase, and Google Scholar between January 1, 2021, and November 6, 2024. The included studies were assessed for risk of bias using the Newcastle-Ottawa tool. Narrative synthesis and random-effects meta-analysis were employed to synthesize the evidence.

Results

Eight studies were included in this systematic review and meta-analysis (134,022 participants). COVID-19 vaccination was significantly associated with a 34% reduction in the odds of antibiotic use (OR: 0.662; 95% CI: 0.540–0.811) in COVID-19 patients. These findings were supported by the sensitivity analyses. In the subgroup analysis, a significant negative association was observed between COVID-19 vaccination and antibiotic use among COVID-19 patients across all study designs. A major limitation of this study is that most of the included studies did not adjust for confounders.

Conclusions

COVID-19 vaccination was associated with a significant reduction in antibiotic use among COVID-19 patients. COVID-19 vaccination status may have influenced healthcare providers' decisions regarding antibiotic use in this group. Further large-scale cohort studies are needed to confirm these findings.

Other

The study protocol is registered with PROSPERO (ID: CRD42023449625). No funding was provided for this study. The APCs were covered by the Karolinska Institute.

疫苗接种被认为是最有效的医疗干预措施之一。除其他益处外，某些疫苗通过减少抗生素的使用有助于减少抗菌素耐药性。考虑到COVID-19大流行期间抗生素耐药性增加的报道，本研究旨在探讨COVID-19疫苗接种状况与COVID-19患者抗生素使用之间的关系。方法系统检索PubMed、Scopus、Web of Science、Embase、谷歌Scholar等于2021年1月1日至2024年11月6日的相关文献。纳入的研究使用纽卡斯尔-渥太华工具评估偏倚风险。采用叙事综合和随机效应荟萃分析进行证据综合。结果本系统评价和荟萃分析共纳入8项研究（134,022名受试者）。COVID-19疫苗接种与COVID-19患者抗生素使用几率降低34%显著相关（OR: 0.662; 95% CI: 0.540-0.811）。这些发现得到敏感性分析的支持。在亚组分析中，在所有研究设计中，观察到COVID-19疫苗接种与COVID-19患者抗生素使用之间存在显著的负相关。本研究的一个主要局限性是大多数纳入的研究没有对混杂因素进行调整。结论COVID-19疫苗接种与COVID-19患者抗生素使用显著减少相关。COVID-19疫苗接种状况可能影响了医疗保健提供者在该组中使用抗生素的决定。需要进一步的大规模队列研究来证实这些发现。其他研究方案在PROSPERO注册（ID: CRD42023449625）。本研究未获资助。这些装甲运兵车由卡罗林斯卡研究所负责。

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引用次数: 0

Assessment of knowledge, attitude and practices regarding standard precautions of infection prevention and control and associated factors among healthcare personnel working at tertiary care hospitals in Punjab, Pakistan 评估巴基斯坦旁遮普省三级保健医院医护人员关于感染预防和控制标准预防措施及相关因素的知识、态度和做法

IF 1.8 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-09-01 Epub Date: 2025-06-06 DOI: 10.1016/j.infpip.2025.100464

Muhammad Kiddeer , Aamir Abbas , Abdul Basit , Tawseef Ahmad , Imran Masood

Background

Inadequate infection control in healthcare settings can increase healthcare-associated infections and worsen morbidity and mortality rates. Standard precautions, applicable to all patients with suspected or confirmed infections, safeguard both healthcare personnel and patients. This study aimed to evaluate knowledge, attitudes and practices regarding standard precautions among healthcare personnel in tertiary care hospitals across Punjab, Pakistan.

Methods

This multi-centre cross-sectional study, conducted from May to July 2019, included 600 healthcare personnel recruited via convenience sampling from tertiary care hospitals in six cities selected at random.

Results

Out of 533 healthcare personnel, the response rate was 88.8%. Most respondents were female (N=341, 64.2%), mean ± standard deviation (SD) age was 28.85 ±7.08 years, and mean ± SD length of service was 5.58 ± 5.78 years. Knowledge, attitudes and practices regarding standard precautions were poor, and only 37.5%, 46.7% and 46.3% of respondents had good knowledge, positive attitudes and safe practices, respectively. Healthcare personnel with >10 years of experience [adjusted odds ratio (AOR) 2.98, 95% confidence interval (CI) 1.60–5.55], previous infection control training (AOR 1.96, 95% CI 1.30–2.94), professional degrees (AOR 2.04, 95% CI 1.16–3.60), and availability of infection control guidelines in their work department were more likely to have good knowledge regarding standard precautions. The availability of infection control guidelines in the work department was also significantly associated with positive attitudes (AOR 2.83, 95% CI 1.76–4.56) and safe practices (AOR 3.46, 95% CI 1.94–6.14).

Conclusion

Knowledge, attitudes and practices of healthcare personnel regarding standard precautions were inadequate. Continuous education and certified training for healthcare personnel can improve infection control measures substantially in public healthcare settings.

背景：在卫生保健机构中，适当的感染控制可增加卫生保健相关感染，并使发病率和死亡率恶化。适用于所有疑似或确诊感染患者的标准预防措施可保护医护人员和患者。本研究旨在评估巴基斯坦旁遮普省三级医院医护人员关于标准预防措施的知识、态度和做法。方法本多中心横断面研究于2019年5月至7月进行，随机抽取6个城市三级医院的600名医护人员进行方便抽样。结果533名医护人员中，应答率为88.8%。女性居多（N=341, 64.2%），平均±标准差（SD）年龄为28.85±7.08岁，平均±SD工龄为5.58±5.78岁。受访者对标准预防措施的了解、态度和做法较差，分别只有37.5%、46.7%和46.3%的受访者对标准预防措施有良好的了解、积极的态度和安全的做法。具有10年经验的卫生保健人员[调整优势比（AOR） 2.98, 95%可信区间（CI） 1.60-5.55]、既往感染控制培训（AOR 1.96, 95% CI 1.30-2.94）、专业学位（AOR 2.04, 95% CI 1.16-3.60）以及其工作部门感染控制指南的可获得性更可能对标准预防措施有良好的了解。工作部门感染控制指南的可获得性也与积极态度（AOR 2.83, 95% CI 1.76-4.56）和安全操作（AOR 3.46, 95% CI 1.94-6.14）显著相关。结论卫生保健人员对标准预防措施的知识、态度和实践不足。对卫生保健人员的持续教育和认证培训可以大大改善公共卫生保健机构的感染控制措施。

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