Infection Prevention in Practice最新文献_第5页

Clinical risk factors for postoperative infection in adult cardiac surgery with cardiopulmonary bypass: a retrospective study 使用心肺旁路的成人心脏手术术后感染的临床风险因素：一项回顾性研究

IF 1.8 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-04-08 DOI: 10.1016/j.infpip.2025.100458

Guangxu Mao , Wensen Chen , Liyun Wang , Sheng Zhao , Feng Zang

Background

Postoperative infection remains a serious problem for patients undergoing open-heart surgery and is associated with poor prognosis and mortality.

Aim

To determine the incidence, characteristics and associated risk factors for nosocomial infections in adult cardiac surgery patients and to develop a nomogram prediction model.

Methods

Data were retrospectively collected from patients who underwent cardiac surgery with cardiopulmonary bypass (CPB) at a tertiary hospital in 2023. Patients were divided into an infected group (N = 130) and a non-infected group (N = 192). Multivariate logistic regression analysis was used to analyse the independent risk factors for healthcare-associated infections after cardiac surgery under CPB.

Results

Of the 1584 patients, 130 (8.21%) developed postoperative infections (infection group). Lower respiratory tract was the most common site of infection (N = 74, 56.9%), while Gram-negative bacteria were the predominant isolates overall (N = 81, 62.3%). Among the Gram-negative bacteria, Acinetobacter baumannii was the most frequently identified, whereas Staphylococcus aureus was the leading strain among Gram-positive bacteria. Multivariate logistic regression analysis of the 322 patients included in the study revealed that CPB duration, American Society of Anaesthesiologists score, procalcitonin concentration on the first postoperative day, monocyte:lymphocyte ratio, preinfection mechanical ventilation duration, and preinfection central venous catheterization duration were the six independent predictors of postoperative infection. The area under the receiver operating characteristic curve was 0.824 (0.778–0.870), and the model showed good predictive performance.

Conclusion

A nomogram has been developed to predict postoperative infection via commonly available data. This tool could assist clinicians in optimising the perioperative care of patients undergoing cardiac surgery with CPB, but further external validation is needed.

背景：术后感染仍然是心内直视手术患者的一个严重问题，并与不良预后和死亡率相关。目的探讨成人心脏手术患者医院感染的发生率、特点及相关危险因素，建立医院感染的nomogram预测模型。方法回顾性收集2023年在某三级医院行心脏手术合并体外循环（CPB）患者的资料。患者分为感染组（N = 130）和非感染组（N = 192）。采用多因素logistic回归分析CPB下心脏手术后医疗相关感染的独立危险因素。结果1584例患者中，130例（8.21%）发生术后感染（感染组）。下呼吸道是最常见的感染部位（N = 74, 56.9%），革兰氏阴性菌为主要分离菌（N = 81, 62.3%）。革兰氏阴性菌中以鲍曼不动杆菌最多检出，革兰氏阳性菌中以金黄色葡萄球菌最多检出。对322例患者进行多因素logistic回归分析，CPB时间、美国麻醉医师学会评分、术后第一天降钙素原浓度、单核细胞：淋巴细胞比值、感染前机械通气时间、感染前中心静脉置管时间是术后感染的6个独立预测因素。受试者工作特征曲线下面积为0.824(0.778 ~ 0.870)，模型具有较好的预测效果。结论利用常用数据，建立了一种预测术后感染的nomogram方法。该工具可以帮助临床医生优化CPB心脏手术患者的围手术期护理，但需要进一步的外部验证。

{"title":"Clinical risk factors for postoperative infection in adult cardiac surgery with cardiopulmonary bypass: a retrospective study","authors":"Guangxu Mao , Wensen Chen , Liyun Wang , Sheng Zhao , Feng Zang","doi":"10.1016/j.infpip.2025.100458","DOIUrl":"10.1016/j.infpip.2025.100458","url":null,"abstract":"<div><h3>Background</h3><div>Postoperative infection remains a serious problem for patients undergoing open-heart surgery and is associated with poor prognosis and mortality.</div></div><div><h3>Aim</h3><div>To determine the incidence, characteristics and associated risk factors for nosocomial infections in adult cardiac surgery patients and to develop a nomogram prediction model.</div></div><div><h3>Methods</h3><div>Data were retrospectively collected from patients who underwent cardiac surgery with cardiopulmonary bypass (CPB) at a tertiary hospital in 2023. Patients were divided into an infected group (<em>N</em> = 130) and a non-infected group (<em>N</em> = 192). Multivariate logistic regression analysis was used to analyse the independent risk factors for healthcare-associated infections after cardiac surgery under CPB.</div></div><div><h3>Results</h3><div>Of the 1584 patients, 130 (8.21%) developed postoperative infections (infection group). Lower respiratory tract was the most common site of infection (<em>N</em> = 74, 56.9%), while Gram-negative bacteria were the predominant isolates overall (<em>N</em> = 81, 62.3%). Among the Gram-negative bacteria, <em>Acinetobacter baumannii</em> was the most frequently identified, whereas <em>Staphylococcus aureus</em> was the leading strain among Gram-positive bacteria. Multivariate logistic regression analysis of the 322 patients included in the study revealed that CPB duration, American Society of Anaesthesiologists score, procalcitonin concentration on the first postoperative day, monocyte:lymphocyte ratio, preinfection mechanical ventilation duration, and preinfection central venous catheterization duration were the six independent predictors of postoperative infection. The area under the receiver operating characteristic curve was 0.824 (0.778–0.870), and the model showed good predictive performance.</div></div><div><h3>Conclusion</h3><div>A nomogram has been developed to predict postoperative infection via commonly available data. This tool could assist clinicians in optimising the perioperative care of patients undergoing cardiac surgery with CPB, but further external validation is needed.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100458"},"PeriodicalIF":1.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143874603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A new classification of personal protective equipment in healthcare settings: Enhancing infection control and prevention 医疗机构个人防护设备的新分类：加强感染控制和预防

IF 1.8 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-03-29 DOI: 10.1016/j.infpip.2025.100460

Hui Jin , Qun Lu , Kaiwen Ni , Xiaoping Ni

引用次数: 0

MRSA: the enduring foe 耐甲氧西林金黄色葡萄球菌：持久的敌人

IF 1.8 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-03-25 DOI: 10.1016/j.infpip.2025.100459

Siobhain Kelly , Gemma Winzor , Simon Ching Lam

引用次数: 0

Efficacy of heparin–vancomycin–amikacin combination lock in preventing catheter-related infections in haemodialysis patients: a double-blind randomized clinical trial 肝素-万古霉素-阿米卡星联锁预防血液透析患者导管相关性感染的疗效：一项双盲随机临床试验

IF 1.8 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-03-14 DOI: 10.1016/j.infpip.2025.100457

A.A. Arabzadeh , M. Iranikia , F. Pourfarzi , B. Shahrami , S. M Kebar

Background

Haemodialysis patients with tunnelled central venous catheters (CVCs) are at high risk for catheter-related infections (CRIs), which can lead to serious complications, prolonged hospitalizations, and increased healthcare costs. The use of antibiotic lock solutions may help prevent these infections. This study evaluates the efficacy of a heparin–vancomycin–amikacin combination lock solution in preventing CRIs compared with heparin alone in haemodialysis patients.

Methods

This single-centre, double-blind randomized clinical trial involved 60 haemodialysis patients with tunnelled CVCs. Patients were randomly assigned to receive either a heparin 5000 units/mL lock (Group A) or a combination of heparin 5000 units/mL, vancomycin 500 mg/mL, and amikacin 500 mg/mL lock (Group B). The primary outcome was the incidence of CRIs, diagnosed using CDC criteria, over a 6-month follow-up period.

Findings

Group B demonstrated a significantly lower incidence of CRIs compared to Group A (P=0.001). Additionally, the mean number of CRI episodes per patient and the CRI rate per 1000 catheter days were significantly lower in Group B (P=0.028 and 0.042, respectively). The rate of catheter removal due to infection was also significantly reduced in Group B (P=0.029). No significant differences in infection timing were observed, although Group B showed later infection onset. No adverse drug reactions were reported.

Conclusions

The heparin–vancomycin–amikacin combination lock solution was more effective in preventing CRIs than heparin alone in haemodialysis patients. Further studies with larger sample sizes and longer follow-up are needed to confirm its long-term benefits and assess potential risks, including antibiotic resistance.

背景：使用隧道中心静脉导管（CVCs）的血液透析患者发生导管相关感染（CRIs）的风险很高，这可能导致严重的并发症、住院时间延长和医疗费用增加。使用抗生素锁溶液可能有助于预防这些感染。本研究比较了肝素-万古霉素-阿米卡星联合锁液在血液透析患者中预防cri的效果，并与单用肝素进行了比较。方法本研究为单中心、双盲随机临床试验，纳入60例血液透析患者。患者被随机分配接受肝素5000单位/mL锁（a组）或肝素5000单位/mL、万古霉素500 mg/mL和阿米卡星500 mg/mL锁（B组）的联合治疗。主要结局是在6个月的随访期间，使用CDC标准诊断的cri发生率。结果：B组cri发生率明显低于a组（P=0.001）。此外，B组患者平均CRI发作次数和每1000导管天CRI率均显著低于B组（P分别=0.028和0.042）。B组因感染拔管率也显著降低（P=0.029）。B组感染发病时间较晚，感染时间无明显差异。未见药物不良反应报告。结论肝素-万古霉素-阿米卡星联合锁液预防血液透析患者cri的效果优于单用肝素。需要进行更大样本量和更长时间随访的进一步研究，以确认其长期益处并评估潜在风险，包括抗生素耐药性。

{"title":"Efficacy of heparin–vancomycin–amikacin combination lock in preventing catheter-related infections in haemodialysis patients: a double-blind randomized clinical trial","authors":"A.A. Arabzadeh , M. Iranikia , F. Pourfarzi , B. Shahrami , S. M Kebar","doi":"10.1016/j.infpip.2025.100457","DOIUrl":"10.1016/j.infpip.2025.100457","url":null,"abstract":"<div><h3>Background</h3><div>Haemodialysis patients with tunnelled central venous catheters (CVCs) are at high risk for catheter-related infections (CRIs), which can lead to serious complications, prolonged hospitalizations, and increased healthcare costs. The use of antibiotic lock solutions may help prevent these infections. This study evaluates the efficacy of a heparin–vancomycin–amikacin combination lock solution in preventing CRIs compared with heparin alone in haemodialysis patients.</div></div><div><h3>Methods</h3><div>This single-centre, double-blind randomized clinical trial involved 60 haemodialysis patients with tunnelled CVCs. Patients were randomly assigned to receive either a heparin 5000 units/mL lock (Group A) or a combination of heparin 5000 units/mL, vancomycin 500 mg/mL, and amikacin 500 mg/mL lock (Group B). The primary outcome was the incidence of CRIs, diagnosed using CDC criteria, over a 6-month follow-up period.</div></div><div><h3>Findings</h3><div>Group B demonstrated a significantly lower incidence of CRIs compared to Group A (<em>P</em>=0.001). Additionally, the mean number of CRI episodes per patient and the CRI rate per 1000 catheter days were significantly lower in Group B (<em>P</em>=0.028 and 0.042, respectively). The rate of catheter removal due to infection was also significantly reduced in Group B (<em>P</em>=0.029). No significant differences in infection timing were observed, although Group B showed later infection onset. No adverse drug reactions were reported.</div></div><div><h3>Conclusions</h3><div>The heparin–vancomycin–amikacin combination lock solution was more effective in preventing CRIs than heparin alone in haemodialysis patients. Further studies with larger sample sizes and longer follow-up are needed to confirm its long-term benefits and assess potential risks, including antibiotic resistance.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100457"},"PeriodicalIF":1.8,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of relative humidity distribution and its impact on disinfection using a combination of robotic fogger and hydrogen peroxide 相对湿度分布及其对双氧水联合喷雾消毒效果的影响

IF 1.8 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-03-05 DOI: 10.1016/j.infpip.2025.100452

Prasanna Kumar Sistla, P. Kanaka Raju

Background

Relative humidity is a key factor in the disinfection process.

Aim

To examine the distribution of relative humidity, and the time required to reach its mean value in the target area when using a robotic fogger with 7.4% hydrogen peroxide.

Methods

The study evaluated the device in both stationary and mobile operation modes. In each mode, relative humidity sensors, along with chemical, biological, and enzyme indicators, were employed to assess the disinfection's effectiveness and consistency.

Results

The device dispersed disinfectant at a rate of 30 mL/min over 45 min in both modes. A shorter time to reach the mean relative humidity is desirable for effective disinfection. It was observed that the mobile mode reached the mean relative humidity 50% faster, maintained this level for an additional 30 min, and achieved an 11% higher relative humidity compared to the stationary mode.

Conclusion

These advancements could assist pharmaceutical manufacturing and healthcare facilities in minimizing downtime during periodic disinfection.

背景相对湿度是消毒过程中的关键因素。目的研究在使用7.4%过氧化氢的自动雾化器时，相对湿度在目标区域的分布，以及达到其平均值所需的时间。方法对该装置在固定和移动两种操作模式下进行评价。在每种模式下，采用相对湿度传感器以及化学、生物和酶指标来评估消毒的有效性和一致性。结果两种消毒方式均以30 mL/min的速度在45 min内分散消毒。较短的时间达到平均相对湿度是有效消毒所需的。观察到，与静止模式相比，移动模式达到平均相对湿度的速度快50%，保持这一水平的时间增加了30分钟，相对湿度提高了11%。结论这些技术进步可以帮助制药企业和医疗机构减少定期消毒的停机时间。

{"title":"Investigation of relative humidity distribution and its impact on disinfection using a combination of robotic fogger and hydrogen peroxide","authors":"Prasanna Kumar Sistla, P. Kanaka Raju","doi":"10.1016/j.infpip.2025.100452","DOIUrl":"10.1016/j.infpip.2025.100452","url":null,"abstract":"<div><h3>Background</h3><div>Relative humidity is a key factor in the disinfection process.</div></div><div><h3>Aim</h3><div>To examine the distribution of relative humidity, and the time required to reach its mean value in the target area when using a robotic fogger with 7.4% hydrogen peroxide.</div></div><div><h3>Methods</h3><div>The study evaluated the device in both stationary and mobile operation modes. In each mode, relative humidity sensors, along with chemical, biological, and enzyme indicators, were employed to assess the disinfection's effectiveness and consistency.</div></div><div><h3>Results</h3><div>The device dispersed disinfectant at a rate of 30 mL/min over 45 min in both modes. A shorter time to reach the mean relative humidity is desirable for effective disinfection. It was observed that the mobile mode reached the mean relative humidity 50% faster, maintained this level for an additional 30 min, and achieved an 11% higher relative humidity compared to the stationary mode.</div></div><div><h3>Conclusion</h3><div>These advancements could assist pharmaceutical manufacturing and healthcare facilities in minimizing downtime during periodic disinfection.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100452"},"PeriodicalIF":1.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143686274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of a patient empowerment hand hygiene programme: a single-centre study in Japan 病人授权手卫生计划的效果：日本的一项单中心研究

IF 1.8 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-03-05 DOI: 10.1016/j.infpip.2025.100456

Yusuke Watanabe , Asami Okugawa , Hiroshi Soeda , Tomohide Shimodaira , Satoko Sato , Hiroaki Fujita , Takehito Kobayashi , Itaru Nakamura , Hidehiro Watanabe

The effectiveness of patient participation in hand hygiene (HH) programmes in Japan is unclear. This study examines the effect of a patient empowerment HH programme at a Japanese hospital. Two periods were analysed: January 2020 to November 2020 as the baseline, and December 2020 to April 2021 as the intervention period. The intervention involved inpatients observing the HH practices of healthcare workers. The average number of HH events per patient-day increased from 23.4 at baseline to 37.3 during the intervention. HH events were positively correlated with the number of patient observations. Patient empowerment programmes may therefore help to improve HH.

在日本，患者参与手部卫生（HH）规划的有效性尚不清楚。本研究考察了日本一家医院患者赋权HH项目的效果。分析了两个时期：2020年1月至2020年11月为基线，2020年12月至2021年4月为干预期。干预涉及住院患者观察卫生保健工作者的HH做法。在干预期间，每位患者每天平均发生HH事件的次数从基线时的23.4次增加到37.3次。HH事件与患者观察次数呈正相关。因此，患者赋权规划可能有助于改善卫生保健。

引用次数: 0

Barriers to hand hygiene practice among healthcare workers in health centres of Kirkos and Akaki Kality sub-cities, Addis Ababa, Ethiopia: a qualitative study 埃塞俄比亚亚的斯亚贝巴Kirkos和Akaki Kality副城市卫生中心卫生工作者手部卫生习惯的障碍：一项定性研究

IF 1.8 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-02-28 DOI: 10.1016/j.infpip.2025.100450

Asmamaw Deguale Worku , Abayneh Melaku

Background

Hand hygiene is an easy step to reduce healthcare-acquired infections, and improve patient safety. Major progress in facility accessibility was made during the coronavirus disease 2019 (COVID-19) pandemic, and this led to greater adherence to hand hygiene practices. However, handwashing practices have now returned to the pre-COVID-19 era. Most of the studies that have investigated hand hygiene adherence are quantitative. As such, this study aimed to explore barriers to hand hygiene practice in the health centres of Kirkos and Akaki Kality sub-cities in Addis Ababa, Ethiopia.

Methods

Twenty-four healthcare professionals employed at the aforementioned health centres were interviewed using the key informant interview method. Data were analysed using a qualitative content analysis technique.

Results

Based on the findings, there were three main categories of barriers to hand hygiene practice: barriers related to individuals (including three sub-categories: lack of knowledge and skill, improper attitude, and poor attention and negligence of healthcare workers); leadership barriers (including two sub-categories: lack of dedicated staff and low attention of leaders); and institutional barriers (including three sub-categories: inappropriate infrastructure and lack of resources, shortage of water, and high work load and staff turnover).

Conclusion

There were several reasons why hand hygiene guidance was not followed. Hand hygiene barriers can be minimized by displaying colour-coded notice boards, making washing facilities easily accessible, monitoring the availability of soap, offering training, and providing accurate evidence about the need to enhance hand hygiene.

背景手部卫生是减少医源性感染和提高患者安全的简便步骤。在 2019 年冠状病毒病（COVID-19）大流行期间，在设施无障碍方面取得了重大进展，这促使人们更加重视手部卫生。然而，现在的洗手方法已经回到了前 COVID-19 时代。大多数调查手部卫生依从性的研究都是定量研究。因此，本研究旨在探讨在埃塞俄比亚亚的斯亚贝巴的 Kirkos 和 Akaki Kality 子城市的医疗中心中手部卫生实践的障碍。结果根据调查结果，手卫生实践的障碍主要有三类：与个人有关的障碍（包括三个子类别：缺乏知识和技能、态度不端正、医护人员不重视和疏忽）；领导障碍（包括两个子类别：缺乏专职人员和领导不重视）；机构障碍（包括三个子类别：基础设施不适当和缺乏资源、缺水、工作量大和人员流动）。手部卫生的障碍可以通过展示彩色编码的告示板、方便使用清洗设施、监测肥皂的供应情况、提供培训以及就加强手部卫生的必要性提供准确的证据来尽量减少。

{"title":"Barriers to hand hygiene practice among healthcare workers in health centres of Kirkos and Akaki Kality sub-cities, Addis Ababa, Ethiopia: a qualitative study","authors":"Asmamaw Deguale Worku , Abayneh Melaku","doi":"10.1016/j.infpip.2025.100450","DOIUrl":"10.1016/j.infpip.2025.100450","url":null,"abstract":"<div><h3>Background</h3><div>Hand hygiene is an easy step to reduce healthcare-acquired infections, and improve patient safety. Major progress in facility accessibility was made during the coronavirus disease 2019 (COVID-19) pandemic, and this led to greater adherence to hand hygiene practices. However, handwashing practices have now returned to the pre-COVID-19 era. Most of the studies that have investigated hand hygiene adherence are quantitative. As such, this study aimed to explore barriers to hand hygiene practice in the health centres of Kirkos and Akaki Kality sub-cities in Addis Ababa, Ethiopia.</div></div><div><h3>Methods</h3><div>Twenty-four healthcare professionals employed at the aforementioned health centres were interviewed using the key informant interview method. Data were analysed using a qualitative content analysis technique.</div></div><div><h3>Results</h3><div>Based on the findings, there were three main categories of barriers to hand hygiene practice: barriers related to individuals (including three sub-categories: lack of knowledge and skill, improper attitude, and poor attention and negligence of healthcare workers); leadership barriers (including two sub-categories: lack of dedicated staff and low attention of leaders); and institutional barriers (including three sub-categories: inappropriate infrastructure and lack of resources, shortage of water, and high work load and staff turnover).</div></div><div><h3>Conclusion</h3><div>There were several reasons why hand hygiene guidance was not followed. Hand hygiene barriers can be minimized by displaying colour-coded notice boards, making washing facilities easily accessible, monitoring the availability of soap, offering training, and providing accurate evidence about the need to enhance hand hygiene.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100450"},"PeriodicalIF":1.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143628104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Methicillin-Resistant Staphylococcus aureus (MRSA) knowledge and awareness among healthcare workers in South-Lebanon 黎巴嫩南部卫生保健工作者对耐甲氧西林金黄色葡萄球菌（MRSA）知识和意识的评估

IF 1.8 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-02-13 DOI: 10.1016/j.infpip.2025.100451

Ali El Roz , Taghrid Chaaban , Hawraa Issa , José-Noel Ibrahim , Zeinab Ezzeddine , Ghassan Ghssein

Background

Methicillin-Resistant Staphylococcus aureus (MRSA) is a well-known cause of hospital acquired infections (HAIs), associated with high rates of morbidity and mortality. In healthcare settings, MRSA can spread via contaminated surfaces and direct contact.

Objective

This study aims to assess the knowledge and awareness of MRSA risks, prevention methods (such as hand hygiene), proper antibiotics use, and multidrug resistance among various groups of healthcare workers (HCWs) in Southern Lebanon.

Methods

A total of 244 HCWs, including those in medical services (MS), paramedical services (PS), and non-medical services (NMS), were conveniently selected for this study. Data was gathered using a structured, validated questionnaire that explored their knowledge and awareness of MRSA risks, prevention measures, hand hygiene practices, and multidrug resistance.

Results

The findings revealed that 68% of HCWs were aware of the origin of MRSA infection, and 61.5% and 51.6% were familiar with its treatment and transmission, respectively. Only 24.2% of HCWs were able to differentiate between hospital-acquired and community-acquired MRSA, 14.7% were aware of the institution's written MRSA control protocols, and 17.6% had heard of MRSA infections. Notably, knowledge and hand hygiene practices were significantly better among MS HCWs than PS and NMS groups (P<0.0001). While all HCWs were familiar with antibiotic usage and drug resistance, NMS HCWs were more likely to use antibiotics without a prescription compared to MS and PS groups (P<0.003).

Conclusion

HCWs in South-Lebanon demonstrated a knowledge gap regarding MRSA risks and prevention guidelines. These findings underscore the need for targeted educational intervention on MRSA, as well as coordinated efforts by healthcare authorities and centres to control MRSA infections.

背景耐甲氧西林金黄色葡萄球菌（MRSA）是众所周知的医院获得性感染（HAIs）的原因，与高发病率和死亡率相关。在医疗环境中，MRSA可以通过污染的表面和直接接触传播。目的本研究旨在评估黎巴嫩南部不同群体卫生保健工作者（HCWs）对MRSA风险、预防方法（如手卫生）、正确使用抗生素和多药耐药性的知识和意识。方法选取244名医疗服务（MS）、辅助医疗服务（PS）和非医疗服务（NMS）的卫生保健工作者作为研究对象。通过结构化的、有效的问卷调查收集数据，探讨他们对MRSA风险、预防措施、手部卫生习惯和多药耐药性的知识和意识。结果68%的医护人员了解MRSA感染的来源，61.5%的医护人员了解MRSA的治疗方法，51.6%的医护人员了解MRSA的传播途径。只有24.2%的医护人员能够区分医院获得性和社区获得性MRSA， 14.7%的医护人员知道医院的MRSA书面控制方案，17.6%的医护人员听说过MRSA感染。值得注意的是，MS组的卫生知识和手卫生习惯明显优于PS组和NMS组（P<0.0001）。虽然所有医护人员都熟悉抗生素的使用和耐药情况，但与MS组和PS组相比，NMS组更有可能在没有处方的情况下使用抗生素（P<0.003）。结论黎巴嫩南部的卫生保健工作者在MRSA风险和预防指南方面存在知识缺口。这些发现强调了有针对性的MRSA教育干预的必要性，以及卫生保健当局和中心协调努力控制MRSA感染的必要性。

{"title":"Assessment of Methicillin-Resistant Staphylococcus aureus (MRSA) knowledge and awareness among healthcare workers in South-Lebanon","authors":"Ali El Roz , Taghrid Chaaban , Hawraa Issa , José-Noel Ibrahim , Zeinab Ezzeddine , Ghassan Ghssein","doi":"10.1016/j.infpip.2025.100451","DOIUrl":"10.1016/j.infpip.2025.100451","url":null,"abstract":"<div><h3>Background</h3><div>Methicillin-Resistant <em>Staphylococcus aureus</em> (MRSA) is a well-known cause of hospital acquired infections (HAIs), associated with high rates of morbidity and mortality. In healthcare settings, MRSA can spread via contaminated surfaces and direct contact.</div></div><div><h3>Objective</h3><div>This study aims to assess the knowledge and awareness of MRSA risks, prevention methods (such as hand hygiene), proper antibiotics use, and multidrug resistance among various groups of healthcare workers (HCWs) in Southern Lebanon.</div></div><div><h3>Methods</h3><div>A total of 244 HCWs, including those in medical services (MS), paramedical services (PS), and non-medical services (NMS), were conveniently selected for this study. Data was gathered using a structured, validated questionnaire that explored their knowledge and awareness of MRSA risks, prevention measures, hand hygiene practices, and multidrug resistance.</div></div><div><h3>Results</h3><div>The findings revealed that 68% of HCWs were aware of the origin of MRSA infection, and 61.5% and 51.6% were familiar with its treatment and transmission, respectively. Only 24.2% of HCWs were able to differentiate between hospital-acquired and community-acquired MRSA, 14.7% were aware of the institution's written MRSA control protocols, and 17.6% had heard of MRSA infections. Notably, knowledge and hand hygiene practices were significantly better among MS HCWs than PS and NMS groups (<em>P</em><0.0001). While all HCWs were familiar with antibiotic usage and drug resistance, NMS HCWs were more likely to use antibiotics without a prescription compared to MS and PS groups (<em>P</em><0.003).</div></div><div><h3>Conclusion</h3><div>HCWs in South-Lebanon demonstrated a knowledge gap regarding MRSA risks and prevention guidelines. These findings underscore the need for targeted educational intervention on MRSA, as well as coordinated efforts by healthcare authorities and centres to control MRSA infections.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100451"},"PeriodicalIF":1.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143480442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Compliance with infection control practices among healthcare workers in radiology departments: a participant observation study and adenosine triphosphate assay evaluation of environmental cleanliness 放射科医护人员对感染控制措施的依从性：一项参与性观察研究和环境清洁度的三磷酸腺苷测定评价

IF 1.8 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-02-11 DOI: 10.1016/j.infpip.2025.100441

Leonia Hiu Wan Lau , Fion Wai Fong Tse , Lorna Kwai Ping Suen , Simon Ching Lam

Background

Increased risk of healthcare-associated infections (HAIs) in radiology departments has been reported in recent years. Optimal infection control practices (ICPs) are the key to controlling HAIs, but few studies have investigated the ICP compliance of healthcare workers (HCWs) in radiology departments.

Aim

To assess the level of ICP compliance of HCWs in a radiology department.

Methods

A participant observation supplemented with adenosine triphosphate (ATP) bioluminescence assay evaluation of environmental cleanliness was conducted. More than 1000 hand hygiene (HH) opportunities and 960 opportunities for the other core ICP elements were observed in different study units of a radiology department. An online checklist powered by eRub was used to record the HCWs' ICP performance. A total of 125 environmental samples were collected for ATP assay evaluation.

Results

In the participants observation, the overall performance score was 41.4%. The lowest score was found in HH (10.4%), followed by use of personal protective equipment (29.4%) and gloves (68.2%). The HH performance was significantly associated with study units (χ² = 42.55, P < 0.001), professional groups (χ² = 110.21, P < 0.001), and patient-to-staff ratio (F = 8.76, P < 0.001). With relative light units of ≤250 set as a pass benchmark, less than two-thirds of the environmental samples passed the ATP assay.

Conclusion

The overall ICP compliance among the HCWs in the radiology department was suboptimal. Revisions of current ICP guidelines and policies that are tailored to the setting-specific needs and barriers in radiology departments is necessary.

背景：近年来，有报道称放射科的医疗保健相关感染（HAIs）风险增加。最佳感染控制措施（ICP）是控制HAIs的关键，但很少有研究调查放射科医护人员（HCWs）对ICP的依从性。目的评价某放射科医护人员对ICP的依从性。方法采用参与观察加三磷酸腺苷（ATP）生物发光法评价环境洁净度。在某放射科的不同研究单位观察到1000多个手部卫生（HH）机会和960多个其他核心ICP要素的机会。使用由eRub提供支持的在线检查表记录医护人员的ICP表现。共收集125份环境样品进行ATP测定评价。结果在参与者观察中，整体表现得分为41.4%。HH（10.4%）得分最低，其次是使用个人防护装备（29.4%）和手套（68.2%）。HH表现与研究单位显著相关(χ2 = 42.55, P <；0.001)，专业组(χ2 = 110.21, P <；0.001)，患者与工作人员比率(F = 8.76, P <；0.001)。以相对光单位≤250作为通过基准，不到三分之二的环境样品通过ATP测定。结论放射科医护人员总体ICP依从性不理想。有必要修订现行的ICP指南和政策，以适应放射科的具体需要和障碍。

{"title":"Compliance with infection control practices among healthcare workers in radiology departments: a participant observation study and adenosine triphosphate assay evaluation of environmental cleanliness","authors":"Leonia Hiu Wan Lau , Fion Wai Fong Tse , Lorna Kwai Ping Suen , Simon Ching Lam","doi":"10.1016/j.infpip.2025.100441","DOIUrl":"10.1016/j.infpip.2025.100441","url":null,"abstract":"<div><h3>Background</h3><div>Increased risk of healthcare-associated infections (HAIs) in radiology departments has been reported in recent years. Optimal infection control practices (ICPs) are the key to controlling HAIs, but few studies have investigated the ICP compliance of healthcare workers (HCWs) in radiology departments.</div></div><div><h3>Aim</h3><div>To assess the level of ICP compliance of HCWs in a radiology department.</div></div><div><h3>Methods</h3><div>A participant observation supplemented with adenosine triphosphate (ATP) bioluminescence assay evaluation of environmental cleanliness was conducted. More than 1000 hand hygiene (HH) opportunities and 960 opportunities for the other core ICP elements were observed in different study units of a radiology department. An online checklist powered by eRub was used to record the HCWs' ICP performance. A total of 125 environmental samples were collected for ATP assay evaluation.</div></div><div><h3>Results</h3><div>In the participants observation, the overall performance score was 41.4%. The lowest score was found in HH (10.4%), followed by use of personal protective equipment (29.4%) and gloves (68.2%). The HH performance was significantly associated with study units (χ<sup>2</sup> = 42.55, <em>P</em> < 0.001), professional groups (χ<sup>2</sup> = 110.21, <em>P</em> < 0.001), and patient-to-staff ratio (<em>F</em> = 8.76, <em>P</em> < 0.001). With relative light units of ≤250 set as a pass benchmark, less than two-thirds of the environmental samples passed the ATP assay.</div></div><div><h3>Conclusion</h3><div>The overall ICP compliance among the HCWs in the radiology department was suboptimal. Revisions of current ICP guidelines and policies that are tailored to the setting-specific needs and barriers in radiology departments is necessary.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100441"},"PeriodicalIF":1.8,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and impact of a structured training module for surgical painting and draping among interns 在实习生中进行外科绘画和悬垂的结构化培训模块的开发和影响

IF 1.8 Q3 INFECTIOUS DISEASES

Infection Prevention in Practice

Pub Date : 2025-02-07 DOI: 10.1016/j.infpip.2025.100439

Tharun Ganapathy Chitrambalam , Abinayaah Suresh , Nidhi Mariam George , Sharmila Aristotle

Background

Surgical site infections (SSIs) are a global concern affecting patient recovery, prolonging hospital stay and raising healthcare costs.

Aim

To address this, a structured training module was implemented to enhance the efficacy of surgical painting and draping among the interns, reducing SSI risk.

Methods

A questionnaire was distributed to 194 interns, covering fundamental inquiries on SSIs, aseptic practices and an assessment of the participant's knowledge regarding preoperative skin preparation and draping. Students then attended lectures, demonstrations, hands-on sessions and an operating room workshop dedicated to surgical painting and draping techniques. Proficiency was evaluated through a follow-up questionnaire.

Results

There was a significant increase in the percentage of good score from 27.6% to 86.9%. A comparative analysis of surgical site infection (SSI) rates at our institution was performed before and after integrating a cohort of trained clinicians.

Conclusion

Although a significant reduction in SSI rates was observed, it cannot be definitively attributed solely to the introduction of the trained personnel. Nonetheless, the findings underscore the potential impact of rigorous training in aseptic techniques on reducing SSI incidence.

手术部位感染（ssi）是影响患者康复、延长住院时间和提高医疗成本的全球性问题。为了解决这个问题，我们实施了一个结构化的培训模块，以提高实习生的手术绘画和悬垂效果，降低SSI风险。方法对194名实习生进行问卷调查，内容包括ssi基本知识、无菌操作、术前皮肤准备和悬垂知识的评估。然后，学生们参加了讲座、示范、实践课程和手术室工作坊，专门学习手术绘画和悬垂技术。通过随访问卷评估熟练程度。结果优良率由27.6%提高到86.9%。对我院外科手术部位感染（SSI）率进行了对比分析，并在整合一组训练有素的临床医生前后进行了比较分析。结论：虽然观察到SSI发生率显著降低，但不能完全归因于培训人员的引入。尽管如此，研究结果强调了严格的无菌技术培训对减少SSI发生率的潜在影响。

{"title":"Development and impact of a structured training module for surgical painting and draping among interns","authors":"Tharun Ganapathy Chitrambalam , Abinayaah Suresh , Nidhi Mariam George , Sharmila Aristotle","doi":"10.1016/j.infpip.2025.100439","DOIUrl":"10.1016/j.infpip.2025.100439","url":null,"abstract":"<div><h3>Background</h3><div>Surgical site infections (SSIs) are a global concern affecting patient recovery, prolonging hospital stay and raising healthcare costs.</div></div><div><h3>Aim</h3><div>To address this, a structured training module was implemented to enhance the efficacy of surgical painting and draping among the interns, reducing SSI risk.</div></div><div><h3>Methods</h3><div>A questionnaire was distributed to 194 interns, covering fundamental inquiries on SSIs, aseptic practices and an assessment of the participant's knowledge regarding preoperative skin preparation and draping. Students then attended lectures, demonstrations, hands-on sessions and an operating room workshop dedicated to surgical painting and draping techniques. Proficiency was evaluated through a follow-up questionnaire.</div></div><div><h3>Results</h3><div>There was a significant increase in the percentage of good score from 27.6% to 86.9%. A comparative analysis of surgical site infection (SSI) rates at our institution was performed before and after integrating a cohort of trained clinicians.</div></div><div><h3>Conclusion</h3><div>Although a significant reduction in SSI rates was observed, it cannot be definitively attributed solely to the introduction of the trained personnel. Nonetheless, the findings underscore the potential impact of rigorous training in aseptic techniques on reducing SSI incidence.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100439"},"PeriodicalIF":1.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143437844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0