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How product development partnerships support hybrid collaborations dealing with global health challenges 产品开发伙伴关系如何支持应对全球卫生挑战的混合合作
Q1 Social Sciences Pub Date : 2020-01-01 DOI: 10.1016/j.glt.2020.09.002
Marjolein J. Hoogstraaten, Wouter P.C. Boon, Koen Frenken

Product Development Partnerships (PDPs) are organizations that target economically-deprived markets, aiming to develop a product by integrating contributions of diverse partners. They have gained importance in the global health arena by targeting and developing drugs for neglected tropical diseases. Their projects are difficult to manage given the multiplicity of roles, objectives and institutional logics of the partners that participate in the collaboration. We explore activities and strategies that platform PDPs – PDPs that orchestrate hybrid project networks – employ to stimulate collaboration between heterogeneous actors. Based on the analysis of two platform PDP projects targeting poverty-related diseases, we propose a framework outlining two innovation collaboration models. With this we support the better understanding of PDPs, which are gaining momentum to facilitate socio-technical transitions across the globe to tackle poverty-related diseases.

产品开发合作伙伴(Product Development Partnerships, pdp)是针对经济落后市场的组织,旨在通过整合不同合作伙伴的贡献来开发产品。它们通过瞄准和开发治疗被忽视的热带病的药物,在全球卫生领域发挥了重要作用。考虑到参与协作的合作伙伴的角色、目标和制度逻辑的多样性,他们的项目很难管理。我们探索了平台pdp(协调混合项目网络的pdp)用来刺激异质参与者之间合作的活动和策略。在分析两个针对贫困相关疾病的平台PDP项目的基础上,我们提出了一个框架,概述了两种创新协作模式。因此,我们支持更好地了解发展中国家计划,这些计划正在加速促进全球社会技术转型,以解决与贫困有关的疾病。
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引用次数: 2
Energy transition in a lockdown: An analysis of the impact of COVID-19 on changes in electricity demand in Lagos Nigeria 封锁期间的能源转型:分析COVID-19对尼日利亚拉各斯电力需求变化的影响
Q1 Social Sciences Pub Date : 2020-01-01 DOI: 10.1016/j.glt.2020.07.002
Norbert Edomah, Gogo Ndulue

In this study, we analyse the role of forced lockdowns on electricity consumption behaviour and its effect on momentary transition in electricity use. Electricity consumption data for residential, commercial and industrial consumers within the Lagos metropolis representing 259 electrical feeder locations were collected and analysed under three scenarios: first, we analyse a business-as-usual scenario without a lockdown; secondly, we analyse the case of a partial lockdown; and finally, we analyse the case of a total lockdown. The study revealed that aside government announcement of the lockdown, certain social practices triggered changes in electricity consumption and use leading to momentary energy transition. Within the residential sector, increased cooking, home laundry, showering, and some professional practices that moved to the homes impacted on higher electricity consumption. Reduced manufacturing practices limited to those involved in food, personal care and pharmaceutical products led to a reduction in electricity use within the industrial sector, while reduced electricity use in the commercial sector was triggered mainly by a scaling down of trading services to essentials. The study concludes by highlighting the impact of changes in electricity demand and consumption under these scenarios and its implications for energy transition and electricity planning.

在本研究中,我们分析了强制封锁对电力消费行为的作用及其对电力使用瞬间转变的影响。收集和分析了拉各斯大都市内代表259个电力馈线地点的住宅、商业和工业消费者的用电量数据,并在三种情况下进行了分析:首先,我们分析了在没有封锁的情况下照常营业的情况;其次,我们分析了部分封锁的情况;最后,我们分析全面封锁的情况。研究显示,除了政府宣布封锁外,某些社会习俗引发了电力消费和使用的变化,导致了短暂的能源过渡。在住宅部门,越来越多的烹饪、家庭洗衣、淋浴和一些搬到家庭的专业实践影响了更高的用电量。仅限于食品、个人护理和医药产品的生产活动减少,导致工业部门用电量减少,而商业部门用电量减少的主要原因是将贸易服务缩减到必需品。该研究最后强调了这些情景下电力需求和消费变化的影响及其对能源转型和电力规划的影响。
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引用次数: 90
Understanding the governance of innovative energy sharing in multi-dwelling buildings through a spatial analysis of consumption practices 通过对消费实践的空间分析,了解多住宅建筑中创新能源共享的治理
Q1 Social Sciences Pub Date : 2020-01-01 DOI: 10.1016/j.glt.2020.09.001
Marta Pappalardo , Gilles Debizet

In collective self-consumption (CSC) communities, citizens come together to produce renewable energy and need to find ways to organise the sharing of consumption at the (micro-)local level. The articulation between the exposure of individual practices and the collective objective of lowering consumption outside solar periods leads to dynamics of social control and privacy preservation that vary according to the nature of spaces. Observing two operations of solar energy sharing in multi-dwelling buildings, our ethnographic analysis investigates the practices of occupying different types of space – from the common to the private - as well as the scenes of discussion among individuals. In this sense, our research reveals a strong intertwining between, on the one hand, the governance of energy communities and, on the other, the spaces in which consumption practices, energy accounting and deliberation processes take place.

在集体自我消费(CSC)社区中,公民聚集在一起生产可再生能源,需要找到在(微观)地方层面组织消费共享的方法。个体实践的暴露与降低太阳周期外消费的集体目标之间的联系导致了根据空间性质而变化的社会控制和隐私保护的动态。通过观察多住宅建筑中太阳能共享的两种操作,我们的民族志分析调查了占用不同类型空间的实践——从公共空间到私人空间——以及个人之间讨论的场景。从这个意义上讲,我们的研究表明,一方面,能源社区的治理与另一方面,消费实践、能源会计和审议过程发生的空间之间存在着强烈的交织。
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引用次数: 5
Advances in air quality modeling and forecasting 空气质量模型和预报的研究进展
Q1 Social Sciences Pub Date : 2020-01-01 DOI: 10.1016/j.glt.2020.11.001
Alexander Baklanov , Yang Zhang

The importance of and interest to research and investigations of atmospheric composition and its modeling for different applications are substantially increased. Air quality forecast (AQF) and assessment systems help decision makers to improve air quality and public health, mitigate the occurrence of acute air pollution episodes, particularly in urban areas, and reduce the associated impacts on agriculture, ecosystems and climate. Advanced approaches in AQF combine an ensemble of state-of-the-art models, high-resolution emission inventories, satellite observations, and surface measurements of most relevant chemical species to provide hindcasts, analyses, and forecasts from global to regional air pollution and downscaling for selected countries, regions, and urban areas. Based on published reviews and recent analyses, the article discusses main gaps, challenges, applications and advances, main trends and research needs in further advancements of atmospheric composition and air quality modeling and forecasting.

研究和调查大气成分及其模拟在不同应用中的重要性和兴趣大大增加。空气质量预报和评估系统有助于决策者改善空气质量和公共卫生,减轻急性空气污染事件的发生,特别是在城市地区,并减少对农业、生态系统和气候的相关影响。AQF的先进方法结合了最先进的模型、高分辨率排放清单、卫星观测和大多数相关化学物质的地面测量,提供从全球到区域空气污染的预测、分析和预测,并为选定的国家、地区和城市地区缩小规模。本文根据已发表的综述和最近的分析,讨论了大气成分和空气质量建模与预报的主要差距、挑战、应用和进展、主要趋势和进一步发展的研究需求。
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引用次数: 43
Predictors of COVID-19 voluntary compliance behaviors: An international investigation COVID-19自愿合规行为的预测因素:一项国际调查
Q1 Social Sciences Pub Date : 2020-01-01 DOI: 10.1016/j.glt.2020.06.003
Cory Clark , Andrés Davila , Maxime Regis , Sascha Kraus

With a large international sample (n = 8317), the present study examined which beliefs and attitudes about COVID-19 predict 1) following government recommendations, 2) taking health precautions (including mask wearing, social distancing, handwashing, and staying at home), and 3) encouraging others to take health precautions. The results demonstrate the importance of believing that taking health precautions will be effective for avoiding COVID-19 and generally prioritizing one’s health. These beliefs continued to be important predictors of health behaviors after controlling for demographic and personality variables. In contrast, we found that perceiving oneself as vulnerable to COVID-19, the perceived severity of catching COVID-19, and trust in government were of relatively little importance. We also found that women were somewhat more likely to engage in these health behaviors than men, but that age was generally unrelated to voluntary compliance behaviors. These findings may suggest avenues and dead ends for behavioral interventions during COVID-19 and beyond.

本研究使用了一个大的国际样本(n = 8317),研究了哪些关于COVID-19的信念和态度可以预测1)遵循政府建议,2)采取卫生预防措施(包括戴口罩、保持社交距离、洗手和呆在家里),以及3)鼓励他人采取卫生预防措施。研究结果表明,相信采取健康预防措施将有效避免COVID-19,并将健康放在首位,这一点很重要。在控制了人口统计学和人格变量后,这些信念仍然是健康行为的重要预测因素。相比之下,我们发现,认为自己容易感染COVID-19、认为感染COVID-19的严重程度以及对政府的信任相对不那么重要。我们还发现,女性在某种程度上比男性更有可能参与这些健康行为,但年龄通常与自愿遵守行为无关。这些发现可能为COVID-19期间及以后的行为干预提供了途径和死胡同。
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引用次数: 414
Participatory development of digital support tools for local-scale energy transitions: Lessons from two European case studies 地方规模能源转型数字支持工具的参与式开发:来自两个欧洲案例研究的经验教训
Q1 Social Sciences Pub Date : 2020-01-01 DOI: 10.1016/j.glt.2020.07.003
Richard J. Hewitt, Cheryl de Boer, Johannes Flacke

Spatial planning systems at local and regional levels are often not well-adapted to the growth of small-scale and local social innovations in renewable energy. Participatory decision support tools have been developed to support the implementation of many areas of environmental policy, but are less common in energy contexts. In response to this knowledge gap, we discuss, compare and contrast the participatory development of two different types of digital support tools for the cases of Spain and the Netherlands, leading to insights into the characteristics that local-level stakeholders find particularly desirable. We adopt an integrative approach, hybridizing implementation theory and action research for, respectively, analysis of implementation characteristics of key actors, and knowledge co-construction with participant stakeholders. The tools developed represent two extremes of the spatial decision support tool spectrum, a simple touchscreen application on the one hand (COLLAGE) and a more complicated spatial model on the other (APoLUS). COLLAGE was used and well-liked by stakeholders, whereas APoLUS was not adopted by the participant group, who nevertheless contributed much essential information to its development. We identify eight key differences between the two tools which shed light on the nature of bottom-up energy transition processes: 1: Target users; 2: Target scale of action; 3: Relevance to users’ needs; 4: Interactive quality; 5: Key emphasis; 6: Level of complexity; 7: Ease of communication of tool rationale; 8: Cost. The differences between these tools also relate to a recognized dichotomy in sustainability transition research, with complex spatial support systems like APoLUS tending towards descriptive-analytical modes of sustainability science and simpler tools like COLLAGE being more clearly related to transformational modes. Approaches to supporting local-scale energy transitions that are able to span both modes are likely to become increasingly relevant as the climate crisis evolves. We also identify a research gap between support tools for implementation of established policy and support tools for transformative actions at local scales, and suggest the study of digital “transition support tools” as a promising avenue for future research.

地方和区域一级的空间规划系统往往不能很好地适应可再生能源方面的小规模和地方社会创新的增长。参与性决策支持工具已经开发出来,以支持环境政策许多领域的实施,但在能源环境中不太常见。针对这一知识差距,我们讨论、比较和对比了西班牙和荷兰案例中两种不同类型的数字支持工具的参与式开发,从而深入了解地方层面利益相关者特别需要的特征。我们采用实施理论与行动研究相结合的方法,分别对关键行为体的实施特征进行分析,并与参与的利益相关者进行知识共建。开发的工具代表了空间决策支持工具谱系的两个极端,一方面是简单的触摸屏应用程序(COLLAGE),另一方面是更复杂的空间模型(APoLUS)。COLLAGE被利益相关者使用并很受欢迎,而APoLUS没有被参与者群体采用,尽管他们为其开发贡献了许多重要信息。我们确定了这两种工具之间的八个关键区别,这些区别揭示了自下而上的能源转型过程的本质:1:目标用户;2:目标行动规模;3:与用户需求相关;4:互动质量;5:重点;6:复杂程度;7:工具基本原理易于沟通;8:成本。这些工具之间的差异也与可持续性转型研究中公认的二分法有关,像APoLUS这样的复杂空间支持系统倾向于可持续性科学的描述分析模式,而像COLLAGE这样的简单工具更明显地与转型模式相关。随着气候危机的发展,支持能够跨越两种模式的地方能源转型的方法可能会变得越来越重要。我们还发现了实施既定政策的支持工具与地方层面变革行动的支持工具之间的研究差距,并建议将数字化“转型支持工具”作为未来研究的一个有希望的途径。
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引用次数: 8
A roadmap for semi-automatically extracting predictive and clinically meaningful temporal features from medical data for predictive modeling 从医学数据中半自动提取预测和临床有意义的时间特征用于预测建模的路线图
Q1 Social Sciences Pub Date : 2019-01-01 DOI: 10.1016/j.glt.2018.11.001
Gang Luo

Predictive modeling based on machine learning with medical data has great potential to improve healthcare and reduce costs. However, two hurdles, among others, impede its widespread adoption in healthcare. First, medical data are by nature longitudinal. Pre-processing them, particularly for feature engineering, is labor intensive and often takes 50–80% of the model building effort. Predictive temporal features are the basis of building accurate models, but are difficult to identify. This is problematic. Healthcare systems have limited resources for model building, while inaccurate models produce suboptimal outcomes and are often useless. Second, most machine learning models provide no explanation of their prediction results. However, offering such explanations is essential for a model to be used in usual clinical practice. To address these two hurdles, this paper outlines: 1) a data-driven method for semi-automatically extracting predictive and clinically meaningful temporal features from medical data for predictive modeling; and 2) a method of using these features to automatically explain machine learning prediction results and suggest tailored interventions. This provides a roadmap for future research.

基于医疗数据的机器学习的预测建模在改善医疗保健和降低成本方面具有巨大的潜力。然而,有两个障碍阻碍了它在医疗保健领域的广泛采用。首先,医学数据本质上是纵向的。预处理它们,特别是特征工程,是劳动密集型的,通常需要50-80%的模型构建工作。预测时间特征是建立准确模型的基础,但很难识别。这是有问题的。医疗保健系统用于模型构建的资源有限,而不准确的模型会产生次优结果,而且通常是无用的。其次,大多数机器学习模型不提供对其预测结果的解释。然而,提供这样的解释对于一个模型在通常的临床实践中使用是必不可少的。为了解决这两个障碍,本文概述了:1)一种数据驱动的方法,用于从医疗数据中半自动提取预测和临床有意义的时间特征,用于预测建模;2)利用这些特征自动解释机器学习预测结果并提出量身定制的干预措施的方法。这为未来的研究提供了路线图。
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引用次数: 15
Environmental and resource burdens associated with low carbon, more electric transition pathways to 2050: Footprint components from carbon emissions and land use to waste arisings and water consumption 与2050年低碳、更电气化的转型途径相关的环境和资源负担:从碳排放和土地利用到废物产生和水消耗的足迹组成部分
Q1 Social Sciences Pub Date : 2019-01-01 DOI: 10.1016/j.glt.2019.01.001
Geoffrey P. Hammond , Hayley R. Howard , Hanumant Singh Rana

Environmental or ‘ecological’ footprints have been widely used in recent years as indicators of resource consumption and waste absorption transformed on the basis of biologically productive land area [in global hectares (gha)] required per capita with prevailing technology. It has been employed here to estimate the footprints associated with three low carbon, more electric transition pathways for the United Kingdom (UK): described as ‘Market Rules’ (MR), ‘Central Co-ordination’ (CC) and ‘Thousand Flowers’ (TF) respectively. These pathways focus on the power sector, including the potential for increasing use of low-carbon electricity for heating and transport, within the context of critical European Union developments and policies. Their overall environmental footprint has been disaggregated into various components: bioproductive and built land, carbon emissions, embodied energy, materials and waste, transport, and water consumption. This component-based approach provides, for example, a means for evaluating the implications for the so-called ‘energy-land-water nexus’. Electricity demand was projected to decrease significantly under the TF pathway by 2050, but its total environmental footprint (EF) was greater than either that under the MR or CC pathways. This is mainly due to the increase in the use of bioproductive land associated with solid biofuel production and that of the carbon footprint, which are both seen to be larger than under either the MR or CC cases. Water and waste footprint components made almost negligibly small contributions under all three transition pathways. Lessons can clearly be drawn for other industrialised nations attempting to decarbonise their electricity generation systems, although local circumstances will determine the country-specific findings.

近年来,环境或“生态”足迹作为资源消耗和废物吸收的指标被广泛使用,该指标是根据现行技术下人均所需的生物生产性土地面积[以全球公顷(gha)为单位]进行转换的。在这里,它被用来估计与英国(UK)的三种低碳、更电气化的过渡途径相关的足迹:分别被称为“市场规则”(MR)、“中央协调”(CC)和“千花”(TF)。这些途径的重点是电力部门,包括在欧盟关键发展和政策的背景下增加低碳电力用于供暖和运输的潜力。他们的总体环境足迹被分解为各种组成部分:生物生产和建设用地、碳排放、隐含能源、材料和废物、运输和水消耗。例如,这种以组成部分为基础的方法提供了一种评估对所谓“能源-陆地-水关系”的影响的方法。预计到2050年,在TF路径下,电力需求将显著下降,但其总环境足迹(EF)大于MR或CC路径下的总环境足迹(EF)。这主要是由于与固体生物燃料生产相关的生物生产性土地的使用增加以及碳足迹的使用增加,这两者都被认为比MR或CC情况下更大。在所有三个过渡路径下,水和废物足迹组成部分的贡献几乎可以忽略不计。其他试图使发电系统脱碳的工业化国家显然可以从中吸取教训,尽管具体结果将由当地情况决定。
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引用次数: 10
Climate change: Disruption, risk and opportunity 气候变化:破坏、风险和机遇
Q1 Social Sciences Pub Date : 2019-01-01 DOI: 10.1016/j.glt.2019.02.001
Alistair Woodward

Climate change is disruptive because virtually all aspects of our lives are best located in the Goldilocks zone: the place where it is “not too hot and not too cold but just right”. Rising greenhouse gases are heating the globe faster than has ever occurred before, and record-breaking intense, extreme weather is becoming more common. In the last three years unexpectedly severe hurricanes, heatwaves and forest fires have affected millions of people. What makes disruption dangerous? I suggest low predictability, high scale, speed and lack of reversibility are good guides. Risks to health are direct and indirect and include also the “transition risks” associated with responses to climate change. Sometimes disruption is welcome because it provides opportunities for radical action that would not be possible otherwise: in this vein, it has been argued that climate change is “not just a challenge, but the greatest public health opportunity of the 21st century”. The co-benefits agenda (justifying climate interventions on the basis of positive outcomes in other sectors) is beguiling: it promises a relatively smooth way forward, but might an emphasis on win-win interventions distract from the radical changes that are needed? There are other reasons for caution – the intersection of climate and health policies may contain trade-offs as well as synergies, and the prospect of future gains that outweigh immediate losses is seldom, on its own, sufficient to change in-grained behaviours and policies.

气候变化具有破坏性,因为我们生活的几乎所有方面都最适合居住在“金发姑娘地带”:即“不太热也不太冷,但刚刚好”的地方。不断上升的温室气体正以前所未有的速度使全球变暖,破纪录的强烈极端天气正变得越来越普遍。在过去的三年里,意外严重的飓风、热浪和森林火灾影响了数百万人。是什么让颠覆变得危险?我认为低可预测性、高规模、高速度和缺乏可逆性是很好的指导。健康风险是直接和间接的,还包括与应对气候变化有关的"过渡风险"。有时破坏是受欢迎的,因为它提供了采取激进行动的机会,否则这些行动是不可能的:在这方面,有人认为气候变化“不仅是一个挑战,而且是21世纪最大的公共卫生机遇”。共同利益议程(在其他领域取得积极成果的基础上证明气候干预措施的合理性)是诱人的:它承诺了一条相对平稳的前进道路,但强调双赢的干预措施是否会分散人们对所需的根本变革的注意力?还有其他需要谨慎的理由——气候和卫生政策的交集可能包含权衡和协同作用,未来收益超过眼前损失的前景本身很少足以改变内在的行为和政策。
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引用次数: 18
Applying open innovation strategies in the context of a regional innovation ecosystem: The case of Janssen Pharmaceuticals 开放式创新战略在区域创新生态系统中的应用:以杨森制药为例
Q1 Social Sciences Pub Date : 2019-01-01 DOI: 10.1016/j.glt.2019.05.001
Joanna Robaczewska , Wim Vanhaverbeke , Annika Lorenz

Open innovation strategies in large firms have been changing considerably during the last 15 years. Some multinationals are now taking a long-term, strategic approach to Open innovation, thereby actively developing a regionally bounded innovation ecosystem. This approach goes beyond the tradition of open innovation, which emphasized the opening of firms’ boundaries for inbound and outbound knowledge flows. In the new approach, multinationals actively shape their innovation environment to better exploit external talent and expertise, share public infrastructure, raise funds and influence public policies - the key enablers for establishing a vibrant, world-class research and development (R&D) environment. We examine one such regionally embedded innovation ecosystem set up by Janssen Pharmaceuticals at its global R&D centre in Beerse, Belgium.

We develop a conceptual framework by integrating Open innovation, Innovation Ecosystems and Regional Economics literature streams. This combination of the three distinct theoretical approaches is required to explain the benefits and working of Janssen Pharmaceuticals’ regionally embedded innovation ecosystem.

在过去的15年里,大公司的开放式创新策略发生了很大的变化。一些跨国公司正在采取长期的、战略性的方法来进行开放式创新,从而积极发展一个区域有限的创新生态系统。这种方法超越了传统的开放式创新,后者强调企业对流入和流出的知识流动开放边界。在新的方法中,跨国公司积极塑造其创新环境,以便更好地利用外部人才和专业知识、共享公共基础设施、筹集资金和影响公共政策——这些都是建立充满活力的世界级研发环境的关键因素。我们考察了由杨森制药公司在其位于比利时贝尔斯的全球研发中心建立的这样一个区域嵌入式创新生态系统。我们通过整合开放式创新、创新生态系统和区域经济学文献流,构建了一个概念框架。这三种不同的理论方法的结合需要解释杨森制药的区域嵌入式创新生态系统的好处和工作。
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引用次数: 31
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Global Transitions
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