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Endometriotic Stones; Can they exist? A case report 异位的石头;它们能存在吗?病例报告
Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.891
M. Ullah
Endometriosis is a gynaecological pathology that manifests as pelvic pain, infertility and cyclical issues. The presence of endometriotic tissue outside the uterus is the hallmark of endometriosis and commonest sites are ovaries, fallopian tubes, uterosacral ligaments and lateral pelvic peritoneum. Ovarian endometriotic cyst (EC) is typically a chocolate cyst that is often diagnosed by a combination of clinical history examination and radiological imaging. However, the definitive diagnosis requires histopathological confirmation. The management is complex and requires long term suppression of menstrual cycle and ovarian cystectomy. We hereby illustrate a case of a young female who presented with EC. During a routine daycare laparoscopic cystectomy, a rare finding of endometriotic stones was ascertained per-operatively. It has not been reported previously as per our knowledge. Patient remained well post operatively and was discharged in evening.
子宫内膜异位症是一种妇科病理,表现为盆腔疼痛、不孕症和周期性问题。子宫外存在子宫内膜异位症是子宫内膜异位症的标志,最常见的部位是卵巢、输卵管、子宫骶韧带和骨盆外侧腹膜。卵巢子宫内膜异位囊肿(EC)是典型的巧克力囊肿,通常通过临床病史检查和放射影像学检查相结合来诊断。然而,明确的诊断需要组织病理学证实。治疗复杂,需要长期抑制月经周期和卵巢囊肿切除术。我们在此说明一个年轻的女性谁提出了EC的情况下。在常规日托腹腔镜膀胱切除术,一个罕见的发现子宫内膜异位性结石是确定的术前。据我们所知,以前没有报道过。患者术后保持良好,于晚间出院。
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引用次数: 0
Outcome of Ultrasound Guided Trucut Biopsy of Adnexal Masses with Suspected Malignancy 超声引导下疑似恶性附件肿块活检的结果
Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.742
Syeda Zakia, Sara Shahid, Syed Murtaza Hussain, Hadia Hina, Hyder Wajid Abbasi, Haseeb Noor
Background: Ultrasound guided sampling techniques are frequently used in the tissue diagnosis of various tumours. Female patients commonly present with adnexal masses and require tissue diagnosis by trucut biopsy for initiation of the treatment. This study was done to determine the outcome of ultrasound guided trucut biopsy in patients presenting with suspected adnexal malignancy. Methodology: This cross sectional study was done at the Department of Radiology, MCH Centre, PIMS hospital, Islamabad from October 2018 to September 2020. In this study, all female patients aged 18 years and above with suspected adnexal malignancy were included. Trucut biopsy was performed under ultrasound guidance, sample sent for histopathology and various histopathological outcomes were assessed. Patients were kept under observation for 2 hours following biopsy. The data was entered and assessed by using SPSS version 24.0. Frequencies and percentages were calculated for nominal data and mean and standard deviation for numerical data. Results: Mean age of the subjects was 50.24±10.52 years and mean duration of symptoms was 2.97±1.23 months. Definitive diagnosis made in 59 (95.1%) out of 62 cases and only 3 (0.04%) cases were inconclusive; among which two showed inadequate sample and one showed normal tubo-ovarian tissue. 90% histopathological findings were conclusive and no complication was reported. Conclusion: Trucut biopsy has high diagnostic yield with no complications and most common malignancy detected was serous cystadenocarcinoma followed by mucinous carcinoma. Key words: Biopsy, Malignancy, Ultrasound  
背景:超声引导取样技术经常用于各种肿瘤的组织诊断。女性患者通常表现为附件肿块,需要组织活检诊断开始治疗。本研究旨在确定疑似附件恶性肿瘤患者行超声引导下活检的结果。方法:本横断面研究于2018年10月至2020年9月在伊斯兰堡PIMS医院MCH中心放射科完成。在本研究中,所有年龄在18岁及以上的疑似附件恶性肿瘤的女性患者均被纳入。超声引导下进行组织活检,送标本进行组织病理检查,评估各项组织病理结果。活检后观察患者2小时。采用SPSS 24.0版本对数据进行录入和评估。对标称数据计算频率和百分比,对数值数据计算平均值和标准差。结果:患者平均年龄50.24±10.52岁,平均症状持续时间2.97±1.23个月。62例确诊59例(95.1%),诊断不明确3例(0.04%);其中2例样本不足,1例卵巢输卵管组织正常。90%的组织病理学结果是结论性的,无并发症报道。结论:肿瘤活检诊断率高,无并发症,最常见的恶性肿瘤是浆液性囊腺癌,其次是粘液性癌。关键词:活检,恶性肿瘤,超声
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引用次数: 0
High Resolution Computed Tomography Chest Findings Among Post-COVID Patients covid后患者的高分辨率计算机断层扫描胸部表现
Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.789
Rabia Shahid, Muhammad Saleem Akhter, Muhammad Waseem, M. Rafiq
  Background: HRCT chest has proven to be a helpful radiological modality to assess the course of disease. The main objective of the study was to analyze the pattern of lung involvement on HRCT chest among post-Covid patients. Methodology: This cross-sectional study was carried out in the post Covid patients (30 days after discharge) from Nov 2020 to July 2021 in Sahiwal Teaching Hospital, Pakistan. Total 180 patients were selected through non probability consecutive sampling technique. Whole body Multi Slice CT scan 128 Slices by GE discovery was used to get HRCT of chest and to document various patterns and stages of pulmonary fibrosis in the post-COVID patients. The data was analyzed using the IBM SPSS 28.0.0 2021. Various radiological findings were expressed in percentages. Results: A total of 77.8% patients had bilateral lung involvement, while 22.2% had unilateral lung involvement after one month of disease. Ground Glass Haze was the commonest radiological pattern, found in 140 (77.8%) cases. Other radiological patterns were Air Space Opacification (47.2%), Septal Thickening (20%) and Fibrotic Bands (26.1%). Traction Bronchiectasis (10%) and Honey Combing (7.8%) were among the lesser ones reported. About 62% patients had mixed findings on HRCT Chest.  Diagnosis of Organizing Pneumonia was made in 166 (92.22%) patients while 14 (7.78%) patients were labelled as UIP (Usual Interstitial Pneumonia) with honey-combing in HRCT chest. The involvement of Right Lower Lobe was in 165 (91.7%) of cases. Right Middle Lobe remained fairly spared and was seen in 120 (66.7%) cases. Conclusion: Patchy ground glass haze seen bilaterally in lower lung lobes are the commonest abnormalities in HRCT chest of post-COVID patients. Keywords: Covid-19, Pneumonia, Radiology
背景:胸部HRCT已被证明是一种有用的放射学方式来评估疾病的进程。该研究的主要目的是分析covid后患者HRCT胸部肺部受累模式。方法:本横断面研究于2020年11月至2021年7月在巴基斯坦Sahiwal教学医院对Covid后患者(出院后30天)进行。采用非概率连续抽样方法,共选取180例患者。采用GE发现的128片多层螺旋CT (Multi - Slice CT),获得胸部HRCT,记录新冠肺炎后患者肺纤维化的不同模式和分期。使用IBM SPSS 28.0.0 2021对数据进行分析。各种放射学表现以百分比表示。结果:发病1个月后,77.8%的患者双侧肺受累,22.2%的患者单侧肺受累。磨玻璃雾是最常见的放射学表现,有140例(77.8%)。其他影像学表现为空气腔混浊(47.2%)、间隔增厚(20%)和纤维化带(26.1%)。牵引性支气管扩张(10%)和蜂蜜梳理(7.8%)是较少报道的。约62%的患者HRCT胸部表现不一。166例(92.22%)诊断为组织性肺炎,14例(7.78%)HRCT胸片表现为常见性间质性肺炎伴蜂窝状。累及右下叶165例(91.7%)。右侧中叶相当完好,120例(66.7%)可见。结论:新冠肺炎后患者HRCT胸部最常见的异常为双侧下肺叶片状磨玻璃雾。关键词:新型冠状病毒肺炎放射学
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引用次数: 0
Evaluation of Dental Caries and Periodontal Health Status in Children with Autism: a Case Control Study 自闭症儿童龋齿和牙周健康状况的评估:一项病例对照研究
Pub Date : 2022-06-30 DOI: 10.35787/jimdc.v11i2.734
Ahmed Bin Khalid Khan, Seeme Nigar, Naseer Ahmed, Anum Tanwir, Chander Kumar, Sara Altamash
Background: Dental problems are common in autistic children due to poor oral hygiene. During the dental treatment, main challenge is reduced ability of autistic kids to communicate. The objective of this study was to investigate about the oral health status of autistic children and to compare the risk of dental caries and periodontal disease between children with autism and healthy controls. Methodology: This case-control study was conducted at the Milestone Charitable Trust and Defense Housing Authority (DHA), Sheikh Khalifa Bin Zayed School, for the duration of 04 months (1st Dec 2019 – 30th March 2020). Among cases, 67 autistic children and among controls,67 healthy children, of age 7 to 17 years, of either gender, were included. All the participants were examined and assessed for presence or absence of any carious lesions, and periodontal health. Data analysis was done using SPSS version 23. Results: The overall mean age of included children was 12.51±2.99 years. Of 134 children, 53.7% were males and 46.3% females. The odds of periodontal disease were 5.52 times higher in autistic children as compared to healthy children (p < .001). The odds of dental caries were 3.43 times higher in autistic children as compared to healthy children (p < .001). In both age groups (<=10 years and >10 years), the risk of periodontal disease and dental caries was higher among autistic children as compared to normal children. While, according to gender, the risk of dental caries was higher among male autistic children as compared to normal children. Conclusion: The odds of dental caries and periodontal disease were higher among autistic children as compared to healthy controls. Keywords: Autism Spectrum Disorder, Dental caries, Periodontitis
背景:由于口腔卫生不良,自闭症儿童的牙齿问题很常见。在牙科治疗过程中,自闭症儿童面临的主要挑战是沟通能力下降。本研究旨在了解自闭症儿童的口腔健康状况,并比较自闭症儿童与健康儿童患龋齿和牙周病的风险。方法:本病例对照研究在谢赫哈利法·本·扎耶德学校里程碑慈善信托和国防住房管理局(DHA)进行,为期04个月(2019年12月1日至2020年3月30日)。在病例中,包括67名自闭症儿童,在对照组中,包括67名年龄在7至17岁之间的健康儿童,不分性别。所有的参与者都被检查和评估是否有任何龋齿损害和牙周健康。数据分析使用SPSS version 23。结果:患儿总体平均年龄为12.51±2.99岁。134名儿童中,男占53.7%,女占46.3%。自闭症儿童患牙周病的几率是健康儿童的5.52倍(p < 0.001)。自闭症儿童患龋齿的几率是健康儿童的3.43倍(p < 0.001)。在这两个年龄组(10岁)中,自闭症儿童患牙周病和龋齿的风险高于正常儿童。然而,从性别上看,男性自闭症儿童患龋齿的风险比正常儿童高。结论:与健康儿童相比,自闭症儿童患龋齿和牙周病的几率更高。关键词:自闭症谱系障碍,龋齿,牙周炎
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引用次数: 0
Reference range of Amniotic Fluid Index (AFI) in primigravidae with gestational age from 37 to 42 weeks in a local (Pakistani) population. 在当地(巴基斯坦)人群中,胎龄为37 ~ 42周的原鸟的羊水指数(AFI)参考范围。
Pub Date : 2022-06-30 DOI: 10.35787/jimdc.v11i2.686
Khurram Khaliq Bhinder, Abdur Raheem, Rayyan Pervez, Raheela Aqeel, Sanam Soomro, Aisha Jang
Background: Amniotic fluid index (AFI) is a key element in fetal biophysical profile that predicts pregnancy outcome especially near term in primigravidae. The objective of the study was to determine a reference range of AFI in primigravidae of a local population having gestational age from 37 to 42 weeks. Methodology: This study was carried out from January 2019 to December 2019 after approval from Institutional Review Board and Ethical Committee at Shifa International hospital, Islamabad, Pakistan. Applying inclusion and exclusion criteria, a sample of 272 was selected. AFI was calculated for each subject using ultrasound and recorded on a data collection sheet. For the sake of simplicity and clinical relevance, the population was further stratified as term pregnancy (gestational age 37-39 weeks) and postdates pregnancy (40-42 weeks). The reference range of AFI was then calculated using mean ±two standard deviations. Results: The reference range of AFI for gestational age of 37-42 weeks (population as a whole) was 6.8- 17.2 cm. For term pregnancy, it was 7.5- 17.5 cm, and for postdate pregnancy, it was 5.8 to 15.4 cm. Conclusion: The reference range of AFI for gestational age of 37 to 42 weeks in Primigravida women was 6.8 to 17.2 cm. There is a decreasing trend in AFI as pregnancy advances from term to postdate. Keywords:  Amniotic Fluid Index, Gestational age, Primigravida, Reference Range.
背景:羊水指数(AFI)是胎儿生物物理特征预测妊娠结局的一个关键因素,尤其是在初生动物中。该研究的目的是确定孕龄在37 - 42周的当地人群中初产妇AFI的参考范围。方法:经巴基斯坦伊斯兰堡Shifa国际医院机构审查委员会和伦理委员会批准,本研究于2019年1月至2019年12月进行。采用纳入和排除标准,选取样本272例。利用超声计算每个受试者的AFI,并记录在数据收集表上。为了简单和临床相关性,将人群进一步分层为足月妊娠(37-39周)和晚期妊娠(40-42周)。然后用平均值±2个标准差计算AFI的参考范围。结果:37 ~ 42周胎龄人群AFI参考范围为6.8 ~ 17.2 cm。足月妊娠为7.5- 17.5厘米,晚期妊娠为5.8 - 15.4厘米。结论:孕龄37 ~ 42周的孕妇AFI参考范围为6.8 ~ 17.2 cm。随着妊娠期的推进,AFI呈下降趋势。关键词:羊水指数,胎龄,初孕,参考范围。
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引用次数: 0
Impact of Extroversion on Oral Health-Related Quality of Life in Prosthodontic Patients 外向性对口腔修复患者口腔健康相关生活质量的影响
Pub Date : 2022-06-30 DOI: 10.35787/jimdc.v11i2.800
Waleed Ishaq, Hira Riaz, M. Chaudhary, Rida Anjum, Salman Ahmad, Sara Bano
Background: Oral health-related quality of life (OHRQoL) is a compound model comprising individualized evaluation of one’s emotional, functional and oral health. It is easily influenced by multiple variables including oral problems, cultural differences and personality traits. Where other personality traits negatively influence OHRQoL, extroversion exhibits a positive association. Contrarily, conflicting results have been reported in literature. The inconsistent results, insufficient local data and cultural differences make it imperative to further investigate. The objective of the study was to determine a correlation between extroversion and OHRQoL in prosthodontic patients. Methodology: This cross-sectional study was conducted in Prosthodontics Department of Islamic International Dental Hospital, Islamabad from May 2018 to April 2019. Sample size was calculated to be 270 with 5% significance level and Spearman correlation coefficient of 0.17. However, 305 patients were included in this study. After obtaining informed consent and recording demographic data, Oral Health Impact Profile-14 (OHIP-14) and Eysenck Personality Questionnaire–Revised Short-scale (EPQ-RS) were used to collect the required data and categorize patients. Results: The bivariate correlation analysis revealed extroversion to be negatively associated (r = -0.220) with OHIP score. It depicts that the more extrovert an individual, the lower the OHIP score (better OHRQoL) and vice versa. Effect modifier analysis revealed inconsistent correlation results for extroversion. Conclusion: A positive correlation has been established between Extroversion and OHRQoL, with inconsistent results after controlling effect modifiers.
背景:口腔健康相关生活质量(OHRQoL)是一个复合模型,包括个人情绪、功能和口腔健康的个性化评估。它很容易受到多种变量的影响,包括口腔问题、文化差异和人格特征。当其他人格特质对OHRQoL产生负向影响时,外向性表现出正相关。相反,文献中报道了相互矛盾的结果。结果的不一致、当地数据的不足以及文化差异使得进一步调查势在必行。本研究的目的是确定外倾性与修复患者生活质量之间的相关性。方法:本横断面研究于2018年5月至2019年4月在伊斯兰堡伊斯兰国际牙科医院修复科进行。计算样本量为270,显著性水平为5%,Spearman相关系数为0.17。然而,本研究纳入了305例患者。在获得知情同意并记录人口统计数据后,使用口腔健康影响问卷-14 (OHIP-14)和艾森克人格问卷-修订短量表(EPQ-RS)收集所需数据并对患者进行分类。结果:双变量相关分析显示外向性与OHIP评分呈负相关(r = -0.220)。它描述了一个人越外向,OHIP得分越低(OHRQoL越好),反之亦然。效应修正因子分析显示外倾性的相关结果不一致。结论:外倾性与OHRQoL之间存在正相关关系,但在控制效应修饰因子后结果不一致。
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引用次数: 0
Post-traumatic stress disorder and Post-traumatic Growth among Police officials; Role of Coping Self Efficacy and Hope 警务人员的创伤后应激障碍与创伤后成长应对自我效能感与希望的作用
Pub Date : 2022-06-30 DOI: 10.35787/jimdc.v11i2.870
Azra Azeem, Nelofar Kiran
Background: Post traumatic stress disorder in the after math of trauma is common. The objective of this study was to find correlation between Post-traumatic stress disorder and contributing factors of growth after trauma in active duty officials of police having direct exposure of trauma during war against terror in Pakistan. Methodology: The cross-sectional study was done on active-duty police officials from Federally Administered Tribal Areas (FATA) of Pakistan in three years duration from Jan, 2019 till December 2021. Non probability purposive sampling technique was used for selection of participants. Post-Traumatic Stress Diagnostic Scale (PDS-5), short form of Comprehensive trauma inventory, Adult Hope Scale and Perceived coping self-efficacy scale were used for data collection. SPSS version 21 was used for data analysis. After descriptive analysis, correlation of variables was checked by Pearson correlation and moderation analysis was done. Results: Age range of the participants was 33.6 ± 6.3 years. There was a significant strong positive correlation of Hope and Perceived self-efficacy with Post traumatic growth and negative correlation with Post Traumatic Stress Disorder. There was a significant increase in post-traumatic growth in presence of hope and perceived self-efficacy. Conclusion: Relationship between post-traumatic stress disorder and post-traumatic growth was moderated by perceived coping self-efficacy and hope.
背景:创伤后应激障碍在创伤后数学中是常见的。摘要本研究旨在探讨巴基斯坦反恐战争中直接暴露于创伤的现役警察的创伤后应激障碍与创伤后成长的相关因素。方法:横断面研究是在2019年1月至2021年12月的三年时间里对巴基斯坦联邦直辖部落地区(FATA)的现役警察官员进行的。采用非概率有目的抽样技术进行研究对象的选择。采用创伤后应激诊断量表(PDS-5)、简易创伤综合量表、成人希望量表和感知应对自我效能量表进行数据收集。使用SPSS version 21进行数据分析。描述性分析后,采用Pearson相关检验各变量的相关性,并进行适度分析。结果:年龄范围为33.6±6.3岁。希望、自我效能感与创伤后成长呈显著正相关,与创伤后应激障碍呈显著负相关。创伤后希望和自我效能感的成长显著增加。结论:创伤后应激障碍与创伤后成长的关系受应对自我效能感和希望的调节。
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引用次数: 0
Inflammatory Myofibroblastic Tumour of Lung, A Rare Entity 肺炎性肌成纤维细胞瘤,一种罕见的肿瘤
Pub Date : 2022-06-30 DOI: 10.35787/jimdc.v11i2.846
Bilal Umair, Sohail saqib, Rashid Husnain, R. Khan, F. Ullah
Inflammatory fibroblastic tumour of lung is a rare mesenchymal tumour usually affecting the children and young adults. It is usually considered as a benign entity however it has high potential for recurrence and local invasion. Exact pathogenesis of tumour is not known. Complete surgical excision is the treatment of choice. Due to high chance of recurrence, patients are usually kept on close follow up. Here we present a case of inflammatory myofibroblastic tumour of lung , who presented with history of pain and shortness of breath.She was diagnosed  a case of inflammatory myofibroblastic tumour with the help of CT scan chest and CT Guided biopsy.She underwent  right sided pneumonectomy and remained symptom free on follow up. Key Words. Inflammatory, Myofibroblasts, Pneumonectomy, Tumour.  
肺炎性纤维母细胞瘤是一种罕见的间充质肿瘤,多见于儿童和青年。它通常被认为是一种良性实体,但它有很高的复发和局部侵袭的可能性。肿瘤的确切发病机制尚不清楚。完全的手术切除是治疗的选择。由于复发率高,患者通常保持密切随访。我们在此报告一例肺炎性肌纤维母细胞瘤,其表现为疼痛和呼吸短促。经胸部CT扫描及CT引导下活检诊断为炎性肌成纤维细胞瘤。她接受了右侧全肺切除术,并在随访中保持无症状。关键字。炎性,肌成纤维细胞,全肺切除术,肿瘤。
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引用次数: 0
COVID 19 Vaccination Related Misconceptions and Myths 与COVID - 19疫苗接种相关的误解和误解
Pub Date : 2022-06-30 DOI: 10.35787/jimdc.v11i2.808
Dr Tamkeen Nishat Jaffry, Dr Hina Shan, Dr Rehma Gillani, Dr Uzma Hassan, Dr Bismillah Sehar, Rubab Zulfiqar
Background: Mass vaccination is the most effective way to fight against COVID 19 but a significant number of people are unwilling to be vaccinated, mainly due to misinformation and false beliefs, associated with this drive. The objective of this study was to identify these misconceptions and myths and associate them with sociodemographic factors. Methodology: This cross sectional survey was conducted on 562 residents of Rawalpindi and Islamabad from July 2021 to November 2021. Data was collected through structured questionnaire both in English and Urdu, analysed by SPSS version 23. χ2-test was used to check the association of categorical data with sociodemographic factors. Results:  Out of all the participants, 328 (58.4%) had received COVID19 vaccination. Among these vaccinated individuals, 81.8% were graduates or above and 74.2% had family income more than Rs.50,000. Out of total, 40.7% respondents believed that, vaccine is harmful for diabetics, hypertensive and heart patients, 40.6% agreed that it is not safe for pregnant or lactating women and 40.4% assumed that they have acquired immunity through natural infection. A strong association of misconceptions and myths was found with residence (p value 0.0001), educational level (p value 0.0010) and monthly income (p value 0.0001). Conclusion: Several misconceptions and myths are related with COVID 19 vaccination, strongly influenced by various socio demographic. Hence, there is a need to launch various campaigns regarding the safety and effectiveness of vaccination. Key words: COVID-19, Misinformation, Vaccine
背景:大规模疫苗接种是抗击COVID - 19最有效的方式,但相当多的人不愿意接种疫苗,主要是由于与此相关的错误信息和错误信念。本研究的目的是识别这些误解和神话,并将其与社会人口因素联系起来。方法:这项横断面调查于2021年7月至2021年11月对拉瓦尔品第和伊斯兰堡的562名居民进行。数据收集采用英语和乌尔都语的结构化问卷,用SPSS 23版进行分析。采用χ2检验检验分类资料与社会人口学因素的相关性。结果:所有参与者中,328人(58.4%)接种了新冠肺炎疫苗。在这些接种疫苗的人中,81.8%是大学毕业生或以上学历,74.2%的家庭收入超过5万卢比。40.7%的受访者认为疫苗对糖尿病、高血压和心脏病患者有害,40.6%的人认为疫苗对孕妇或哺乳期妇女不安全,40.4%的人认为他们通过自然感染获得了免疫力。发现误解和神话与居住地(p值0.0001)、教育水平(p值0.0010)和月收入(p值0.0001)密切相关。结论:与COVID - 19疫苗接种有关的一些误解和神话受到各种社会人口统计学的强烈影响。因此,有必要开展各种关于疫苗接种安全性和有效性的运动。关键词:COVID-19,错误信息,疫苗
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引用次数: 0
Clinical Presentation and Outcome of Covid-19 Infection in Patients Undergoing Maintenance Hemodialysis 维持性血液透析患者Covid-19感染的临床表现和结局
Pub Date : 2022-06-30 DOI: 10.35787/jimdc.v11i2.694
Muhammad Ali, Shafique ahmed, Abdul Manan Junejo, Ayesha Ejaz, Hina Iram, Heer Gul
Background: WHO declared Covid-19 a pandemic disease; although 80% of patients with CoV-2 infection have no or mild symptoms, the remaining 20% of patients develop complications. In patients undergoing dialysis, mortality could be higher than that in the general population. This study was conducted to assess the frequency, clinical presentation, and outcome of COVID-19 infection in patients of end-stage renal disease (ESRD) on maintenance hemodialysis. Methodology: This Cross-sectional study was conducted at Department of Nephrology, Jinnah Postgraduate Medical Centre, Karachi, from April to September 2020. This study included 130 patients of either gender of End-Stage Renal Disease on maintenance hemodialysis for at least 3 months. Two Samples for COVID-19 PCR were taken through nasal swab. Blood samples were collected for hemoglobin level, total and differential leucocyte count, platelet count, intact Parathyroid hormone, vitamin D level, Urea, Creatinine, ferritin, transferrin saturation, procalcitonin, D-Dimer, C-reactive proteins, and lactate dehydrogenase.  Radiological assessment was done by X-ray Chest. Urea reduction ratio and single pool Kt/V was used for assessment of adequacy of hemodialysis. Results: Out of 130 patients on hemodialysis, COVID-19 was detected in 52 patients, of which males were 69.2% and females were 30.8%. The most common presentation was shortness of breath (28.8%), followed by cough (19.2%). Home isolation was advised to 38.5% while noninvasive ventilation was given to 34.6%. Mechanically ventilated patients were 26.9%. There were 63.5% patients who recovered and were discharged from the hospital or home-isolated, while 19 patients died (36.5%). Conclusion: COVID-19 pandemic has high chances of infection with increased mortality in people with chronic diseases, especially those having ESRD on hemodialysis. This spreading of infection can be hampered with standard measures of disinfection in centers, social distancing in patients, and the use of a face mask. Keywords: Covid-19, Cough, Hemodialysis, Home isolation, Ventilation  
背景:世卫组织宣布Covid-19为大流行疾病;尽管80%的冠状病毒感染患者没有症状或症状轻微,但其余20%的患者出现并发症。在接受透析的患者中,死亡率可能高于一般人群。本研究旨在评估终末期肾病(ESRD)维持性血液透析患者中COVID-19感染的频率、临床表现和结局。方法:本横断面研究于2020年4月至9月在卡拉奇真纳研究生医学中心肾内科进行。本研究纳入了130例终末期肾病患者,不论男女,均接受维持性血液透析治疗至少3个月。采用鼻拭子法采集2份COVID-19 PCR样本。采集血样检测血红蛋白水平、白细胞总数和差异数、血小板计数、完整甲状旁腺激素、维生素D水平、尿素、肌酐、铁蛋白、转铁蛋白饱和度、降钙素原、D-二聚体、c反应蛋白和乳酸脱氢酶。胸部x光检查。采用尿素还原比和单池Kt/V评价血液透析充分性。结果:130例血液透析患者中检出新冠肺炎52例,其中男性占69.2%,女性占30.8%。最常见的表现是呼吸短促(28.8%),其次是咳嗽(19.2%)。38.5%建议居家隔离,34.6%建议无创通气。机械通气患者占26.9%。康复出院或居家隔离患者63.5%,死亡19例(36.5%)。结论:2019冠状病毒病(COVID-19)大流行感染的几率高,慢性疾病患者,特别是血液透析患者的死亡率增加。通过在中心采取标准消毒措施、在患者中保持社交距离以及使用口罩,可以阻止这种感染的传播。关键词:Covid-19,咳嗽,血液透析,家庭隔离,通风
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引用次数: 0
期刊
Journal of Islamabad Medical and Dental College
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