首页 > 最新文献

Journal of Islamabad Medical and Dental College最新文献

英文 中文
Effect of Pretreatment of Lignocaine Versus Midazolam in the Prevention of Etomidate Induced Myoclonus 利多卡因预处理与咪达唑仑对依托咪酯性肌阵挛的预防作用
Pub Date : 2023-01-03 DOI: 10.35787/jimdc.v11i4.661
F. Batool, A. Ali, S. Lodhi, J. Zahir
Background: The myoclonus after induction of anesthesia with etomidate can lead to increased risk of regurgitation and aspiration. We conducted this study to compare the effectiveness of midazolam and lidocaine for the prevention of etomidate induced myoclonus. Methodology: This randomized controlled trial was done in the Department of Anesthesiology and Intensive Care, Holy Family Hospital, Rawalpindi from January-June 2015 after approval of hospital ethical committee. Informed consent (written) was taken from 224 patients. Patients were allocated into 2 equal groups randomly with the help of computer-generated numbers. Two minutes after induction with etomidate, Group A got 1 ml of 2% lidocaine, and one ml (1 mg) of midazolam was given to Group B. Myoclonus was evaluated in the following one minute, after which 0.5 mg/kg of succinylcholine was given to the patient to facilitate endotracheal intubation. Time of onset of induction was marked by loss of eyelash reflex. Myoclonus was recorded at 20, 40, and 60 seconds. Drug was found to be effective if there was no myoclonus within one minute of etomidate induction. Analysis of data was done using SPSS 17. Results: Lignocaine was effective in preventing myoclonus in 55.40% of patients and Midazolam prevented it in 69.60%. The variation between the results of the groups was found significant statistically. (P< 0.05) Conclusion: Both midazolam and lignocaine are effective in preventing the occurrence of myoclonus associated with etomidate. However, midazolam is the more effective of the two drugs. Keywords: Etomidate, Lignocaine, Midazolam, Myoclonus  
背景:依托咪酯麻醉诱导后的肌阵挛可导致反流和误吸的风险增加。我们进行这项研究是为了比较咪达唑仑和利多卡因预防依托咪酯诱导的肌阵挛的有效性。方法:本随机对照试验经医院伦理委员会批准,于2015年1 - 6月在拉瓦尔品第圣家医院麻醉与重症监护科进行。获取224例患者的知情同意书(书面)。根据计算机生成的数字,将患者随机分为两组。乙咪酯诱导2分钟后,A组给予2%利多卡因1 ml, b组给予咪达唑仑1 ml (1 mg), 1分钟后评价肌收缩,术后给予琥珀胆碱0.5 mg/kg,便于气管插管。诱导开始的时间以睫毛反射的丧失为标志。肌阵挛在20秒、40秒和60秒时被记录下来。如果依托咪酯诱导1分钟内没有肌阵挛,则发现药物是有效的。数据分析采用SPSS 17软件。结果:利多卡因预防肌阵挛的有效率为55.40%,咪达唑仑预防率为69.60%。两组结果差异有统计学意义。结论:咪达唑仑和利多卡因均能有效预防依托咪酯合并肌阵挛的发生。然而,咪达唑仑是两种药物中更有效的一种。关键词:依托咪酯;利多卡因;咪达唑仑
{"title":"Effect of Pretreatment of Lignocaine Versus Midazolam in the Prevention of Etomidate Induced Myoclonus","authors":"F. Batool, A. Ali, S. Lodhi, J. Zahir","doi":"10.35787/jimdc.v11i4.661","DOIUrl":"https://doi.org/10.35787/jimdc.v11i4.661","url":null,"abstract":"Background: The myoclonus after induction of anesthesia with etomidate can lead to increased risk of regurgitation and aspiration. We conducted this study to compare the effectiveness of midazolam and lidocaine for the prevention of etomidate induced myoclonus. \u0000Methodology: This randomized controlled trial was done in the Department of Anesthesiology and Intensive Care, Holy Family Hospital, Rawalpindi from January-June 2015 after approval of hospital ethical committee. Informed consent (written) was taken from 224 patients. Patients were allocated into 2 equal groups randomly with the help of computer-generated numbers. Two minutes after induction with etomidate, Group A got 1 ml of 2% lidocaine, and one ml (1 mg) of midazolam was given to Group B. Myoclonus was evaluated in the following one minute, after which 0.5 mg/kg of succinylcholine was given to the patient to facilitate endotracheal intubation. \u0000Time of onset of induction was marked by loss of eyelash reflex. Myoclonus was recorded at 20, 40, and 60 seconds. Drug was found to be effective if there was no myoclonus within one minute of etomidate induction. Analysis of data was done using SPSS 17. \u0000Results: Lignocaine was effective in preventing myoclonus in 55.40% of patients and Midazolam prevented it in 69.60%. The variation between the results of the groups was found significant statistically. (P< 0.05) \u0000Conclusion: Both midazolam and lignocaine are effective in preventing the occurrence of myoclonus associated with etomidate. However, midazolam is the more effective of the two drugs. \u0000Keywords: Etomidate, Lignocaine, Midazolam, Myoclonus \u0000 ","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81667155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Diffuse Large B Cell Lymphoma Presenting as Chest Wall Mass: A Case Report 原发性弥漫性大B细胞淋巴瘤表现为胸壁肿块1例
Pub Date : 2023-01-03 DOI: 10.35787/jimdc.v11i4.903
Dr Muhammad Zeeshan, Professor Dr Shajee Ahmed Siddiqui, Dr Muhammad Azhar Jamil, Dr Ghazal Iftikhar, Dr Adil Farooq
Primary chest wall masses or tumors can be of two types, either benign or malignant. Diffuse large B cell lymphoma (DLBCL) is an aggressive type of non-Hodgkin lymphoma (NHL). Though an aggressive malignancy, with timely and appropriate treatment, approximately two-third of all patients can be cured. We present a rare case of DLBCL presenting as chest wall mass. This case suggests the possibility of the presence of primary malignant B cell lymphoma, with the presentation as a chest wall lesion. Keywords: Chest mass, Diffuse large B cell lymphoma, Mass, Non- Hodgkin’s lymphoma.
原发性胸壁肿块或肿瘤可分为良性和恶性两种类型。弥漫性大B细胞淋巴瘤(DLBCL)是一种侵袭性非霍奇金淋巴瘤(NHL)。虽然是一种侵袭性恶性肿瘤,但通过及时和适当的治疗,大约三分之二的患者可以治愈。我们报告一例罕见的以胸壁肿块表现的大基底细胞淋巴瘤。本病例提示原发性恶性B细胞淋巴瘤的可能性,表现为胸壁病变。关键词:胸部肿块,弥漫性大B细胞淋巴瘤,肿块,非霍奇金淋巴瘤
{"title":"Primary Diffuse Large B Cell Lymphoma Presenting as Chest Wall Mass: A Case Report","authors":"Dr Muhammad Zeeshan, Professor Dr Shajee Ahmed Siddiqui, Dr Muhammad Azhar Jamil, Dr Ghazal Iftikhar, Dr Adil Farooq","doi":"10.35787/jimdc.v11i4.903","DOIUrl":"https://doi.org/10.35787/jimdc.v11i4.903","url":null,"abstract":"Primary chest wall masses or tumors can be of two types, either benign or malignant. Diffuse large B cell lymphoma (DLBCL) is an aggressive type of non-Hodgkin lymphoma (NHL). Though an aggressive malignancy, with timely and appropriate treatment, approximately two-third of all patients can be cured. We present a rare case of DLBCL presenting as chest wall mass. This case suggests the possibility of the presence of primary malignant B cell lymphoma, with the presentation as a chest wall lesion. \u0000Keywords: Chest mass, Diffuse large B cell lymphoma, Mass, Non- Hodgkin’s lymphoma.","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90246199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perception of Ethics and Professionalism Teaching among Dental Professionals at a Teaching Hospital in Karachi 卡拉奇某教学医院牙科专业人员的道德观念与专业教学
Pub Date : 2023-01-03 DOI: 10.35787/jimdc.v11i4.645
Rubab Jawed, Dr Ruqayyah Quresh Hashmi, Dr Hafsa Usman, Dr Mehtab, Dr Saba Sabir
Background: Health care professionals come across many ethically difficult situations in their clinical practices and community; the students should be equipped with skills to resolve ethical and professional issues. Methodology: A cross-sectional study was conducted at Baqai dental college, Karachi. All the faculty members and house officers of the dental teaching hospital were included in the study. The tool used for the data collection was a structured questionnaire, for drawing views of the participants on professionalism and ethics teaching. The survey instrument evaluated two domains; attitudes 25 items, and goals 19 items on ethics and professionalism education. Data were recorded and analyzed in SPSS 24. To compare the responses of both the groups, that is, the house officers and the faculty member’s independent t-test was applied to compare the mean scores. A p-value of ≤ 0.05 was considered significant. Results: The questionnaire was circulated to a total of 157 participants (75 faculty members and 82 house officers) with a 100% response rate. The faculty members and the house officers showed a positive attitude regarding ethics, professionalism, and teachings. The participants agreed with the goals that can be achieved by incorporating professionalism and medical ethics in education. The participant strongly affirmed the learning and teaching of professionalism (4.06 ± 0.989). Conclusion: The realization of the need to teach ethics and professionalism by dental professionals is the first step to bringing change in their daily clinical practice and interpersonal qualities. Keywords: Ethics, Professionalism, “Education, Medical”, “Personality development”, “Social Desirability”.  
背景:卫生保健专业人员在临床实践和社区中遇到许多道德困难的情况;学生应该具备解决道德和专业问题的技能。方法:在卡拉奇Baqai牙科学院进行了一项横断面研究。所有牙科教学医院的教职员工和住院部工作人员均被纳入研究。用于数据收集的工具是一份结构化的问卷,用于绘制参与者对专业和道德教学的看法。该调查工具评估了两个领域;道德与职业教育的态度25项,目标19项。数据用SPSS 24进行记录和分析。为了比较两组的反应,即采用院务人员和教员的独立t检验来比较平均分数。p值≤0.05被认为是显著的。结果:问卷共发放157名参与者(75名教员和82名院务人员),回复率为100%。教职员工和宿舍管理人员在道德、专业和教学方面表现出积极的态度。与会者同意将专业精神和医德纳入教育可以实现的目标。学员对专业学与教的肯定度较高(4.06±0.989)。结论:认识到对牙科专业人员进行道德和职业教育的必要性,是改变其日常临床实践和人际交往素质的第一步。关键词:伦理、专业、“教育、医学”、“人格发展”、“社会可取性”。
{"title":"Perception of Ethics and Professionalism Teaching among Dental Professionals at a Teaching Hospital in Karachi","authors":"Rubab Jawed, Dr Ruqayyah Quresh Hashmi, Dr Hafsa Usman, Dr Mehtab, Dr Saba Sabir","doi":"10.35787/jimdc.v11i4.645","DOIUrl":"https://doi.org/10.35787/jimdc.v11i4.645","url":null,"abstract":"Background: Health care professionals come across many ethically difficult situations in their clinical practices and community; the students should be equipped with skills to resolve ethical and professional issues. \u0000Methodology: A cross-sectional study was conducted at Baqai dental college, Karachi. All the faculty members and house officers of the dental teaching hospital were included in the study. The tool used for the data collection was a structured questionnaire, for drawing views of the participants on professionalism and ethics teaching. The survey instrument evaluated two domains; attitudes 25 items, and goals 19 items on ethics and professionalism education. Data were recorded and analyzed in SPSS 24. To compare the responses of both the groups, that is, the house officers and the faculty member’s independent t-test was applied to compare the mean scores. A p-value of ≤ 0.05 was considered significant. \u0000Results: The questionnaire was circulated to a total of 157 participants (75 faculty members and 82 house officers) with a 100% response rate. The faculty members and the house officers showed a positive attitude regarding ethics, professionalism, and teachings. The participants agreed with the goals that can be achieved by incorporating professionalism and medical ethics in education. The participant strongly affirmed the learning and teaching of professionalism (4.06 ± 0.989). \u0000Conclusion: The realization of the need to teach ethics and professionalism by dental professionals is the first step to bringing change in their daily clinical practice and interpersonal qualities. \u0000Keywords: Ethics, Professionalism, “Education, Medical”, “Personality development”, “Social Desirability”. \u0000 ","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90305058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Benefits of Tissue Marking by Poster Ink in Histopathology 海报油墨组织标记在组织病理学中的比较效益
Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.751
Dr. Ayesha Sarwar, Prof. Ashok Kumar Tanwni, Dr. Anum Usman, Khalida Moeed
Background: Tissue margin marking with India ink is important in decision making for surgeons. The present study was conducted to examine the reliability of different shades of locally available poster colours in tissue marking and to evaluate the colour perceptibility microscopically in comparison with similar tissues marked by India ink. Methodology: This experimental study was conducted at Department of Pathology, HBS Medical & Dental College & Hospital, Islamabad from 27th February 2021 to 29th April 2021. Sample size was fifty, collected through convenient sampling technique. Five types of formalin fixed tissue specimens were selected for the study so as to evaluate the effectiveness of poster ink marking on different tissue surfaces. From each specimen, four sections were taken from the margins. Three shades of poster colour (black, blue and green) were used to ink three sections while one section from each tissue type was marked with India ink. After complete tissue processing and routine haematoxylin and eosin (H&E) staining, slides were examined microscopically. Scoring was done on a scale 0 to 3 on the basis of visibility. Results: The present study showed that poster colours inking of the tissues was quite reliable as compared to India ink. Most consistent results were achieved with black and blue colours as compared to green colour. Conclusion: Poster colours are reliable tool for tissue marking when India ink is not available. Their availability in a variety of colours provides them an edge over India ink. Key words: Eosin, India ink, Resection Margins
背景:用墨迹标记组织边缘在外科医生的决策中是重要的。本研究的目的是检查不同色调的当地可用的海报颜色在组织标记的可靠性,并评估颜色的可感知性在显微镜下与印度墨水标记的类似组织进行比较。方法:本实验研究于2021年2月27日至2021年4月29日在伊斯兰堡HBS医学与牙科学院和医院病理学系进行。样本量为50,采用方便抽样技术采集。选取五种福尔马林固定组织标本进行研究,以评价海报油墨在不同组织表面的标记效果。从每个标本的边缘处取4块切片。三种色调的海报颜色(黑色,蓝色和绿色)被用于墨水的三个部分,而每个组织类型的一个部分被标记为印度墨水。经过完整的组织处理和常规的苏木精和伊红(H&E)染色后,切片进行显微镜检查。评分是根据可见度从0到3分进行的。结果:本研究表明,与印度墨水相比,海报颜色墨水的组织是相当可靠的。与绿色相比,黑色和蓝色获得了最一致的结果。结论:在没有墨水的情况下,海报颜色是一种可靠的组织标记工具。它们有多种颜色可供选择,这使它们比印度墨水更有优势。关键词:伊红,印墨,切缘
{"title":"Comparative Benefits of Tissue Marking by Poster Ink in Histopathology","authors":"Dr. Ayesha Sarwar, Prof. Ashok Kumar Tanwni, Dr. Anum Usman, Khalida Moeed","doi":"10.35787/jimdc.v11i3.751","DOIUrl":"https://doi.org/10.35787/jimdc.v11i3.751","url":null,"abstract":"Background: Tissue margin marking with India ink is important in decision making for surgeons. The present study was conducted to examine the reliability of different shades of locally available poster colours in tissue marking and to evaluate the colour perceptibility microscopically in comparison with similar tissues marked by India ink. \u0000Methodology: This experimental study was conducted at Department of Pathology, HBS Medical & Dental College & Hospital, Islamabad from 27th February 2021 to 29th April 2021. Sample size was fifty, collected through convenient sampling technique. Five types of formalin fixed tissue specimens were selected for the study so as to evaluate the effectiveness of poster ink marking on different tissue surfaces. From each specimen, four sections were taken from the margins. Three shades of poster colour (black, blue and green) were used to ink three sections while one section from each tissue type was marked with India ink. After complete tissue processing and routine haematoxylin and eosin (H&E) staining, slides were examined microscopically. Scoring was done on a scale 0 to 3 on the basis of visibility. \u0000Results: The present study showed that poster colours inking of the tissues was quite reliable as compared to India ink. Most consistent results were achieved with black and blue colours as compared to green colour. \u0000Conclusion: Poster colours are reliable tool for tissue marking when India ink is not available. Their availability in a variety of colours provides them an edge over India ink. \u0000Key words: Eosin, India ink, Resection Margins","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89850154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Universal Health Coverage in Pakistan: A call for Health System Reforms 巴基斯坦全民健康覆盖:呼吁卫生系统改革
Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.910
Admin Jimdc, Baba Sheikh
The sustainable development goal 3.8, adopted in 2015 by the United Nations advocated the need for ‘Universal Health Coverage’ (UHC), a roadmap promising that all people, particularly those in need, have access to essential health services when and where they need, without any financial hardship. UHC is not a new lexicon, it was outlined in the founding constitution of the World Health Organization (WHO) that has stipulated health as a fundamental and universal right of every human being without distinction of race, religion and political belief, economic and social condition. WHO defines ‘maximum’ population coverage, health service coverage, and financial protection, as three dimensions of UHC. The first dimension is relatively simpler to understand: what proportion of the people in the catchment of a health facility are covered for health services, and how many are left out. The second dimension delineates the range of essential health services made available to the people e.g. immunization, family planning, antenatal care, delivery by skilled birth attendant, treatment of common ailments, and services for HIV/AIDS, tuberculosis and malaria etc. Third dimension is about the expenditure incurred while seeking the healthcare, especially the out of pocket expenditure or the cost sharing by the patient, which is supposed
联合国于2015年通过的可持续发展目标3.8倡导需要实现“全民健康覆盖”,这是一份路线图,承诺所有人,特别是有需要的人,能够随时随地获得基本卫生服务,而不会出现任何经济困难。全民健康覆盖并不是一个新词汇,它是在世界卫生组织(世卫组织)的创始宪法中概述的,该宪法规定健康是每个人的基本和普遍权利,不分种族、宗教和政治信仰、经济和社会条件。世卫组织将“最大”人口覆盖率、卫生服务覆盖率和财务保护定义为全民健康覆盖的三个方面。第一个方面相对较容易理解:在卫生设施的集水区,有多少人享有卫生服务,有多少人被排除在外。第二大方面描述了向人民提供的基本保健服务的范围,例如免疫接种、计划生育、产前护理、熟练助产士接生、常见病治疗以及艾滋病毒/艾滋病、结核病和疟疾等服务。第三个维度是指在就医过程中发生的费用,特别是患者自付的费用或应由患者分担的费用
{"title":"Universal Health Coverage in Pakistan: A call for Health System Reforms","authors":"Admin Jimdc, Baba Sheikh","doi":"10.35787/jimdc.v11i3.910","DOIUrl":"https://doi.org/10.35787/jimdc.v11i3.910","url":null,"abstract":"The sustainable development goal 3.8, adopted in 2015 by the United Nations advocated the need for ‘Universal Health Coverage’ (UHC), a roadmap promising that all people, particularly those in need, have access to essential health services when and where they need, without any financial hardship. UHC is not a new lexicon, it was outlined in the founding constitution of the World Health Organization (WHO) that has stipulated health as a fundamental and universal right of every human being without distinction of race, religion and political belief, economic and social condition. WHO defines ‘maximum’ population coverage, health service coverage, and financial protection, as three dimensions of UHC. The first dimension is relatively simpler to understand: what proportion of the people in the catchment of a health facility are covered for health services, and how many are left out. The second dimension delineates the range of essential health services made available to the people e.g. immunization, family planning, antenatal care, delivery by skilled birth attendant, treatment of common ailments, and services for HIV/AIDS, tuberculosis and malaria etc. Third dimension is about the expenditure incurred while seeking the healthcare, especially the out of pocket expenditure or the cost sharing by the patient, which is supposed","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83164559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utility of Cell Block with p53 Immunostain in Diagnosing Urothelial Carcinoma 细胞阻滞与p53免疫染色在尿路上皮癌诊断中的应用
Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.709
N. Nabi, A. Ali, M. Fatima, Armaghana Qamar Khan, Henna Azmat, Ashok Kumar Tanwani
Background: Urine cytology is an initial noninvasive screening test done in patients with suspected urothelial carcinoma. The objective of this study was to compare the sensitivity of conventional smear cytology with cell block technique for the diagnosis of malignant cells in urine and to assess the efficacy of p53 immuno-marker in the diagnosis and prognosis of urinary bladder cancer. Methodology:   The study was carried out in the department of Histopathology, Pakistan Institute of Medical Sciences(PIMS), Islamabad. Cell blocks and cytology smears and were prepared from urine samples of 80 patients of urothelial carcinoma and p53 stain was applied. Data was analyzed using version 21. Sensitivity of conventional smear and cell block techniques were calculated for both low and high grade urothelial carcinomas. Results:The sensitivity of detecting atypical cells using conventional smear was 31% and 70.6% for low grade and high grade urothelial tumors respectively. The sensitivity increased to 41.4% and 84.3% for low and high grade urothelial carcinomas respectively with cell block technique. Positive p53 stain was seen in 13.8% of cases with low grade tumors and 66.7% cases with high grade tumors. Chi-square test was used to find the association of cytology findings with the histologic grade. Conclusion: Sensitivity of urine cell blocks is higher than the conventional smear method for detecting high grade lesions. It can be used as an efficient non-invasive technique and an adjunct tool for the determination of disease relapse and overall survival in patients. Keywords: Carcinoma, Cytology, P53 Protein, Urine
背景:尿细胞学检查是对疑似尿路上皮癌患者进行的初步无创筛查试验。本研究的目的是比较常规涂片细胞学和细胞阻断技术对尿液中恶性细胞的诊断敏感性,并评估p53免疫标记物在膀胱癌诊断和预后中的作用。方法:本研究在伊斯兰堡巴基斯坦医学科学研究所(PIMS)组织病理学部进行。对80例尿路上皮癌患者的尿液样本进行细胞阻滞和细胞学涂片,并应用p53染色。使用版本21分析数据。计算了常规涂片和细胞阻断技术对低级别和高级别尿路上皮癌的敏感性。结果:常规涂片对低级别和高级别尿路上皮肿瘤的非典型细胞检测灵敏度分别为31%和70.6%。细胞阻断技术对低级别和高级别尿路上皮癌的敏感性分别为41.4%和84.3%。低级别肿瘤13.8%阳性,高级别肿瘤66.7%阳性。卡方检验用于发现细胞学结果与组织学分级的关系。结论:尿细胞阻滞法检测高级别病变的灵敏度高于常规涂片法。它可以作为一种有效的非侵入性技术和辅助工具来确定疾病复发和患者的总生存期。关键词:癌,细胞学,P53蛋白,尿
{"title":"Utility of Cell Block with p53 Immunostain in Diagnosing Urothelial Carcinoma","authors":"N. Nabi, A. Ali, M. Fatima, Armaghana Qamar Khan, Henna Azmat, Ashok Kumar Tanwani","doi":"10.35787/jimdc.v11i3.709","DOIUrl":"https://doi.org/10.35787/jimdc.v11i3.709","url":null,"abstract":"Background: Urine cytology is an initial noninvasive screening test done in patients with suspected urothelial carcinoma. The objective of this study was to compare the sensitivity of conventional smear cytology with cell block technique for the diagnosis of malignant cells in urine and to assess the efficacy of p53 immuno-marker in the diagnosis and prognosis of urinary bladder cancer. \u0000Methodology:   The study was carried out in the department of Histopathology, Pakistan Institute of Medical Sciences(PIMS), Islamabad. Cell blocks and cytology smears and were prepared from urine samples of 80 patients of urothelial carcinoma and p53 stain was applied. Data was analyzed using version 21. Sensitivity of conventional smear and cell block techniques were calculated for both low and high grade urothelial carcinomas. \u0000Results:The sensitivity of detecting atypical cells using conventional smear was 31% and 70.6% for low grade and high grade urothelial tumors respectively. The sensitivity increased to 41.4% and 84.3% for low and high grade urothelial carcinomas respectively with cell block technique. Positive p53 stain was seen in 13.8% of cases with low grade tumors and 66.7% cases with high grade tumors. Chi-square test was used to find the association of cytology findings with the histologic grade. \u0000Conclusion: Sensitivity of urine cell blocks is higher than the conventional smear method for detecting high grade lesions. It can be used as an efficient non-invasive technique and an adjunct tool for the determination of disease relapse and overall survival in patients. \u0000Keywords: Carcinoma, Cytology, P53 Protein, Urine","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86732582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Audit of Laparoscopic Cholecystectomy; at a Tertiary Care Hospital in Islamabad 腹腔镜胆囊切除术的审计分析在伊斯兰堡的一家三级护理医院
Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.774
M. Ullah
Background: Laparoscopic Cholecystectomy is a commonly performed surgery and is a gold standard for the treatment of cholelithiasis as it has fewer side effects. This study was conducted to determine indications and complications of this surgery at a tertiary care hospital in Islamabad. Methodology: This retrospective study was conducted in the department of Surgery, Maroof International Hospital from March 2017 to March 2019. A total of 250 patients who underwent laparoscopic cholecystectomy were included through consecutive sampling technique. The data regarding age, gender, mode of presentation, types of presentation, per operative findings, operative complications and duration of hospital stay was collected from patients’ medical record. Statistical Package for Social Sciences SPSS version 23 was used to analyze data. Results:  Mean age of the participants was 46.24 ± 14.13 years. Female to male ratio was 2.73:1. Almost 38.4% patients had chronic cholecystitis, 35.2% had symptomatic gallstone disease, 24.8% had acute cholecystitis and 1.6% had gallbladder polyps. No major vascular or common bile duct injury were noted. 27.2% patients had per operative gallbladder perforation. Stone spillage occurred in 8.8% patients with retrieval in all of them. 75.2% patients were discharged on day 1. Per operatively, 98.4% patients had cholelithiasis, 59.6% had adhesions, 9.6% had mucocele, 1.6% had empyema and 0.8% patients had collections. Conclusion: Laparoscopic cholecystectomy is a safe procedure in all types of gallstone disease presentations with low complication rate. Key words: Cholelithiasis, Gallstones, Laparoscopic Cholecystectomy, Per-operative complications
背景:腹腔镜胆囊切除术是一种常用的手术,由于其副作用少,是治疗胆石症的金标准。本研究是在伊斯兰堡一家三级医院进行的,目的是确定该手术的适应症和并发症。方法:本回顾性研究于2017年3月至2019年3月在Maroof国际医院外科进行。通过连续抽样技术,共纳入250例行腹腔镜胆囊切除术的患者。从患者的医疗记录中收集有关年龄、性别、表现方式、表现类型、每次手术发现、手术并发症和住院时间的数据。使用Statistical Package for Social Sciences SPSS version 23分析数据。结果:患者平均年龄46.24±14.13岁。男女比例为2.73:1。慢性胆囊炎38.4%,有症状性胆结石35.2%,急性胆囊炎24.8%,胆囊息肉1.6%。无大血管或胆总管损伤。27.2%的患者术后发生胆囊穿孔。8.8%的患者术后均出现结石溢出。75.2%患者在第1天出院。术后98.4%的患者有胆石症,59.6%的患者有粘连,9.6%的患者有粘液囊肿,1.6%的患者有脓胸,0.8%的患者有积液。结论:腹腔镜胆囊切除术是一种安全的手术方法,适用于所有类型的胆结石疾病,并发症发生率低。关键词:胆石症;胆结石;腹腔镜胆囊切除术
{"title":"An Audit of Laparoscopic Cholecystectomy; at a Tertiary Care Hospital in Islamabad","authors":"M. Ullah","doi":"10.35787/jimdc.v11i3.774","DOIUrl":"https://doi.org/10.35787/jimdc.v11i3.774","url":null,"abstract":"Background: Laparoscopic Cholecystectomy is a commonly performed surgery and is a gold standard for the treatment of cholelithiasis as it has fewer side effects. This study was conducted to determine indications and complications of this surgery at a tertiary care hospital in Islamabad. \u0000Methodology: This retrospective study was conducted in the department of Surgery, Maroof International Hospital from March 2017 to March 2019. A total of 250 patients who underwent laparoscopic cholecystectomy were included through consecutive sampling technique. The data regarding age, gender, mode of presentation, types of presentation, per operative findings, operative complications and duration of hospital stay was collected from patients’ medical record. Statistical Package for Social Sciences SPSS version 23 was used to analyze data. \u0000Results:  Mean age of the participants was 46.24 ± 14.13 years. Female to male ratio was 2.73:1. Almost 38.4% patients had chronic cholecystitis, 35.2% had symptomatic gallstone disease, 24.8% had acute cholecystitis and 1.6% had gallbladder polyps. No major vascular or common bile duct injury were noted. 27.2% patients had per operative gallbladder perforation. Stone spillage occurred in 8.8% patients with retrieval in all of them. 75.2% patients were discharged on day 1. Per operatively, 98.4% patients had cholelithiasis, 59.6% had adhesions, 9.6% had mucocele, 1.6% had empyema and 0.8% patients had collections. \u0000Conclusion: Laparoscopic cholecystectomy is a safe procedure in all types of gallstone disease presentations with low complication rate. \u0000Key words: Cholelithiasis, Gallstones, Laparoscopic Cholecystectomy, Per-operative complications","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89043514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitotic Index and Immunohistochemical Expression of Ki-67 in Pleomorphic Adenoma of Salivary Glands 涎腺多形性腺瘤有丝分裂指数及Ki-67免疫组织化学表达
Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.777
Faiz Rasul
. Background: Pleomorphic adenomas (PAs) are the most common type of salivary gland tumors (SGTs) which may undergo malignant transformation to Carcinoma ex PA (CaExPA). The purpose of this study was to determine mitotic index (MI) and expression of Ki-67 in Pleomorphic adenomas of salivary gland tumors. Methodology: This study was carried out on sixty patients of pleomorphic adenoma. Slides with specimens were stained with Hematoxylin & Eosin to count Mitotic index. Labeling Index (LI) of Ki-67 was determined immunohistochemically. Mitotic figures (MF) were counted in 10 HPF selected in the proliferative area. MI was scored as 1 (0 to 4 MF per 10 HPF); 2 (5-9 MF per 10 HPF) and 3 (> 9 MF per 10 HPF). Immunoexpression of Ki-67 was scored as ‘0-negative’ when <5% of neoplastic cells stained, ‘1-weak positive’ when 5-19% of neoplastic cells were stained, ‘2-moderate positive’ when 20-49% of neoplastic cells were stained, and ‘3-strong positive’ when >50% of neoplastic cells were stained with Ki-67. Data was, entered in SPSS 21. Results: Mean age was 38.7 ± 12.86 years. Out of 60 cases, 26 (43.33%) were of males while 34 (56.67%) were of females. Expression of Ki-67 was negative in 50% while remaining weak positive. Only score 01 of MI observed. Conclusion:  Ki-67 is more sensitive marker than mitotic index in pleomorphic adenomas even in small sized tumors and it can help in detection of malignant transformation of PAs. Keywords: Adenomas, Immunohistochemistry, Ki-67 Antigen, Parotid Neoplasms, Pleomorphic
. 背景:多形性腺瘤(PAs)是唾液腺肿瘤中最常见的类型,可恶性转化为癌前PA (CaExPA)。本研究的目的是测定涎腺肿瘤多形性腺瘤有丝分裂指数(MI)和Ki-67的表达。方法:本研究对60例多形性腺瘤患者进行分析。切片用苏木精和伊红染色,计数有丝分裂指数。免疫组织化学法测定Ki-67的标记指数(LI)。在增殖区选取10个HPF计数有丝分裂图(MF)。MI评分为1 (0 ~ 4 MF / 10 HPF);2 (5- 9mf / 10 HPF)和3 (> 9mf / 10 HPF)。50%肿瘤细胞Ki-67染色后,Ki-67免疫表达评分为“0阴性”。数据在SPSS 21中输入。结果:平均年龄38.7±12.86岁。60例患者中,男性26例(43.33%),女性34例(56.67%)。50%的Ki-67表达为阴性,其余为弱阳性。MI仅为01分。结论:Ki-67在多形性腺瘤中是比有丝分裂指数更敏感的标志物,可用于PAs的恶性转化检测。关键词:腺瘤,免疫组织化学,Ki-67抗原,腮腺肿瘤,多形性
{"title":"Mitotic Index and Immunohistochemical Expression of Ki-67 in Pleomorphic Adenoma of Salivary Glands","authors":"Faiz Rasul","doi":"10.35787/jimdc.v11i3.777","DOIUrl":"https://doi.org/10.35787/jimdc.v11i3.777","url":null,"abstract":". \u0000Background: Pleomorphic adenomas (PAs) are the most common type of salivary gland tumors (SGTs) which may undergo malignant transformation to Carcinoma ex PA (CaExPA). The purpose of this study was to determine mitotic index (MI) and expression of Ki-67 in Pleomorphic adenomas of salivary gland tumors. \u0000Methodology: This study was carried out on sixty patients of pleomorphic adenoma. Slides with specimens were stained with Hematoxylin & Eosin to count Mitotic index. Labeling Index (LI) of Ki-67 was determined immunohistochemically. Mitotic figures (MF) were counted in 10 HPF selected in the proliferative area. MI was scored as 1 (0 to 4 MF per 10 HPF); 2 (5-9 MF per 10 HPF) and 3 (> 9 MF per 10 HPF). Immunoexpression of Ki-67 was scored as ‘0-negative’ when <5% of neoplastic cells stained, ‘1-weak positive’ when 5-19% of neoplastic cells were stained, ‘2-moderate positive’ when 20-49% of neoplastic cells were stained, and ‘3-strong positive’ when >50% of neoplastic cells were stained with Ki-67. Data was, entered in SPSS 21. \u0000Results: Mean age was 38.7 ± 12.86 years. Out of 60 cases, 26 (43.33%) were of males while 34 (56.67%) were of females. Expression of Ki-67 was negative in 50% while remaining weak positive. Only score 01 of MI observed. \u0000Conclusion:  Ki-67 is more sensitive marker than mitotic index in pleomorphic adenomas even in small sized tumors and it can help in detection of malignant transformation of PAs. \u0000Keywords: Adenomas, Immunohistochemistry, Ki-67 Antigen, Parotid Neoplasms, Pleomorphic","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81275037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A breakthrough in Alzheimer’s Disease 阿尔茨海默病的一个突破
Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.793
Taimoor Hassan
Alzheimer's disease is among the most prevalent types of dementia worldwide. Studying mice models, Australian researchers discovered one of the possible origins of Alzheimer's disease. The discovery has been termed a "breakthrough" by some. Scientists have gained a better grasp of why and how Alzheimer's disease arises by researching the blood-brain barrier. Their findings point to possible therapy and preventive strategies for the neurodegenerative disorder.
阿尔茨海默病是世界上最常见的痴呆症之一。通过研究老鼠模型,澳大利亚研究人员发现了阿尔茨海默病的可能起源之一。这一发现被一些人称为“突破”。通过研究血脑屏障,科学家们对阿尔茨海默病的发病原因和发病机制有了更好的了解。他们的发现为神经退行性疾病提供了可能的治疗和预防策略。
{"title":"A breakthrough in Alzheimer’s Disease","authors":"Taimoor Hassan","doi":"10.35787/jimdc.v11i3.793","DOIUrl":"https://doi.org/10.35787/jimdc.v11i3.793","url":null,"abstract":"Alzheimer's disease is among the most prevalent types of dementia worldwide. Studying mice models, Australian researchers discovered one of the possible origins of Alzheimer's disease. The discovery has been termed a \"breakthrough\" by some. Scientists have gained a better grasp of why and how Alzheimer's disease arises by researching the blood-brain barrier. Their findings point to possible therapy and preventive strategies for the neurodegenerative disorder.","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84854960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Disease Severity and Treatment on Quality of Life in Patients of Psoriasis 疾病严重程度及治疗对银屑病患者生活质量的影响
Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.823
Palvisha Qadri, S. Tabassum, U. Chhipa
Background: Psoriasis is a common inflammatory dermatosis with significantly challenging clinical needs in patient management. Given its chronicity and social stigmatization, the burden on health-related life quality is substantial. The objective of this study was to assess psychosocial and financial impact of disease severity and treatment modalities on patients’ life quality. Methodology: A total of 93 clinically diagnosed patients with Psoriasis were included in this cross-sectional study. Quality of life was assessed through Dermatology Life Quality Index (DLQI) scoring system and disease severity by Psoriasis area severity index (PASI) respectively. Treatment modalities were evaluated by filling out a brief questionnaire. Descriptive analyses were presented as mean ± SD for symmetrically distributed variables while median with interquartile range (IQR) were reported for non-symmetrically distributed variables. Association was determined by Chi-square test considering p-value ≤0.05 as significant. Results: There were 47.3% male and 52.7% female patients. The Median DLQI score was 6.00 with an IQR of 7. Topical treatment was used in the majority of patients currently (60%). Quality of life ( QOL) for 41.9% of cases was mildly affected. Rest of the cases were affected more severely, consisting of 47.3% with moderate and 10.8% with severe impact on quality of life. Significant association of DLQI scores was found with disease severity and current treatment modalities. Conclusion: Different therapies along with disease severity, remarkably affect QoL among psoriasis patients. KEYWORDS Disease Severity ,Impact, Psoriasis , Quality of Life, Treatment
背景:银屑病是一种常见的炎症性皮肤病,在患者管理方面具有显著的临床挑战性。鉴于其长期性和社会污名化,与健康有关的生活质量负担沉重。本研究的目的是评估疾病严重程度和治疗方式对患者生活质量的心理社会和经济影响。方法:本横断面研究共纳入93例临床诊断为银屑病的患者。采用Dermatology life Quality Index (DLQI)评分系统评价生活质量,采用Psoriasis area severity Index (PASI)评价疾病严重程度。通过填写一份简短的问卷来评估治疗方式。对于对称分布的变量,描述性分析采用均数±标准差表示,而对于非对称分布的变量,采用四分位数范围(IQR)的中位数报告。以p值≤0.05为显著性,采用卡方检验确定相关性。结果:男性占47.3%,女性占52.7%。DLQI评分中位数为6.00,IQR为7。目前大多数患者(60%)采用局部治疗。41.9%的患者生活质量(QOL)轻度受影响。其余病例影响较严重,其中47.3%为中度影响,10.8%为重度影响。DLQI评分与疾病严重程度和当前治疗方式有显著关联。结论:不同治疗方法对银屑病患者的生活质量有显著影响。关键词:疾病严重程度,影响,银屑病,生活质量,治疗
{"title":"The Impact of Disease Severity and Treatment on Quality of Life in Patients of Psoriasis","authors":"Palvisha Qadri, S. Tabassum, U. Chhipa","doi":"10.35787/jimdc.v11i3.823","DOIUrl":"https://doi.org/10.35787/jimdc.v11i3.823","url":null,"abstract":"Background: Psoriasis is a common inflammatory dermatosis with significantly challenging clinical needs in patient management. Given its chronicity and social stigmatization, the burden on health-related life quality is substantial. The objective of this study was to assess psychosocial and financial impact of disease severity and treatment modalities on patients’ life quality. \u0000Methodology: A total of 93 clinically diagnosed patients with Psoriasis were included in this cross-sectional study. Quality of life was assessed through Dermatology Life Quality Index (DLQI) scoring system and disease severity by Psoriasis area severity index (PASI) respectively. Treatment modalities were evaluated by filling out a brief questionnaire. Descriptive analyses were presented as mean ± SD for symmetrically distributed variables while median with interquartile range (IQR) were reported for non-symmetrically distributed variables. Association was determined by Chi-square test considering p-value ≤0.05 as significant. \u0000Results: There were 47.3% male and 52.7% female patients. The Median DLQI score was 6.00 with an IQR of 7. Topical treatment was used in the majority of patients currently (60%). Quality of life ( QOL) for 41.9% of cases was mildly affected. Rest of the cases were affected more severely, consisting of 47.3% with moderate and 10.8% with severe impact on quality of life. Significant association of DLQI scores was found with disease severity and current treatment modalities. \u0000Conclusion: Different therapies along with disease severity, remarkably affect QoL among psoriasis patients. \u0000KEYWORDS \u0000Disease Severity ,Impact, Psoriasis , Quality of Life, Treatment","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79639180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Islamabad Medical and Dental College
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1