Pub Date : 2023-04-19DOI: 10.35787/jimdc.v12i1.974
Admin Jimdc, Aliya Batool, Sadaf Khalid
{"title":"Establishing and Sustaining a Peadiatric Bone Marrow Transplant Program in Developing Countries","authors":"Admin Jimdc, Aliya Batool, Sadaf Khalid","doi":"10.35787/jimdc.v12i1.974","DOIUrl":"https://doi.org/10.35787/jimdc.v12i1.974","url":null,"abstract":"","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75841372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.35787/jimdc.v12i1.973
Ayesha Iftikhar
The inflammatory fibroid polyp (IFP) usually presents as a solitary benign polyp that arises from the submucosa of the gastrointestinal tract. It occurs more commonly in males and stomach is the favored site followed by ileum, colon and duodenum. Multiple inflammatory fibroid polyps (IFPs) is a rare occurrence, so we thought of presenting a case of a 40 years old female with multiple inflammatory fibroid polyps (IFPs). She presented with abdominal pain and abdominal fullness. Her C.T. abdomen showed multiple lobulated soft tissue masses causing intussusception. Surgical resection was done, and histopathological examination of these polyps showed features of IFPs. A literature review of 9 cases (including ours) between 2000-2022 is also presented. To our knowledge this is the third female patient with multiple IFPs.
{"title":"Multiple Inflammatory Fibroid Polyps in a Female; A case Report","authors":"Ayesha Iftikhar","doi":"10.35787/jimdc.v12i1.973","DOIUrl":"https://doi.org/10.35787/jimdc.v12i1.973","url":null,"abstract":"The inflammatory fibroid polyp (IFP) usually presents as a solitary benign polyp that arises from the submucosa of the gastrointestinal tract. It occurs more commonly in males and stomach is the favored site followed by ileum, colon and duodenum. Multiple inflammatory fibroid polyps (IFPs) is a rare occurrence, so we thought of presenting a case of a 40 years old female with multiple inflammatory fibroid polyps (IFPs). She presented with abdominal pain and abdominal fullness. Her C.T. abdomen showed multiple lobulated soft tissue masses causing intussusception. Surgical resection was done, and histopathological examination of these polyps showed features of IFPs. A literature review of 9 cases (including ours) between 2000-2022 is also presented. To our knowledge this is the third female patient with multiple IFPs.","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72612177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.35787/jimdc.v12i1.676
Hassam Anjum Mir, Saima Shafiq, Maheen Khan, Sumbal Mukhtar, Ali Asif, Qayyum Akhter
Background: Cone beam CT (CBCT) is an advancement of conventional CT that uses a divergent pyramidal or conical X-ray beam for imaging the craniofacial complex. Studies on the maxillary sinus and its relationship with the roots present within its close proximity are mostly based on computed tomography imaging and rarely being based on cone-beam computed tomography (CBCT). This study aims to determine the relationship of maxillary sinus and the mesiobuccal root of maxillary first molar using cone beam computed tomography (CBCT). Methods: The study was conducted in Armed Forces Institute of Dentistry (AFID) from Sept, 2019 to Feb, 2020. 142 CBCTs were studied in the duration of six months. The distance between the maxillary mesiobuccal root and floor of maxillary sinus was measured using the built in software. The data collected was analyzed using SPSS 23. p-value of <0.005 was considered significant. Results: The mean distance was -0.85 mm ± 2.56 on left side and -0.74mm ± 2.40 on right side. There was no significant difference between left and right side. The correlation between age and left and right-side measurements was statistically significant, p-value 0.000. Conclusion: The relationship of maxillary sinus and the mesiobuccal root of maxillary first molar is significant. The study shows that in dentate healthy patients, the maxillary mesiobuccal molar root is nearly in contact with the sinus floor. These findings lead to the conclusion that performing surgical procedures in maxillary molar region may invariably lead to sinus perforation if one is not care full. Keywords: Cone beam computerized tomography, Dental implant, Maxillary sinus, Molar
{"title":"Relationship of Maxillary Sinus and Maxillary First Molar Root Using Cone Beam Computed Tomography","authors":"Hassam Anjum Mir, Saima Shafiq, Maheen Khan, Sumbal Mukhtar, Ali Asif, Qayyum Akhter","doi":"10.35787/jimdc.v12i1.676","DOIUrl":"https://doi.org/10.35787/jimdc.v12i1.676","url":null,"abstract":"Background: Cone beam CT (CBCT) is an advancement of conventional CT that uses a divergent pyramidal or conical X-ray beam for imaging the craniofacial complex. Studies on the maxillary sinus and its relationship with the roots present within its close proximity are mostly based on computed tomography imaging and rarely being based on cone-beam computed tomography (CBCT). This study aims to determine the relationship of maxillary sinus and the mesiobuccal root of maxillary first molar using cone beam computed tomography (CBCT). \u0000Methods: The study was conducted in Armed Forces Institute of Dentistry (AFID) from Sept, 2019 to Feb, 2020. 142 CBCTs were studied in the duration of six months. The distance between the maxillary mesiobuccal root and floor of maxillary sinus was measured using the built in software. The data collected was analyzed using SPSS 23. p-value of <0.005 was considered significant. \u0000Results: The mean distance was -0.85 mm ± 2.56 on left side and -0.74mm ± 2.40 on right side. There was no significant difference between left and right side. The correlation between age and left and right-side measurements was statistically significant, p-value 0.000. \u0000Conclusion: The relationship of maxillary sinus and the mesiobuccal root of maxillary first molar is significant. The study shows that in dentate healthy patients, the maxillary mesiobuccal molar root is nearly in contact with the sinus floor. These findings lead to the conclusion that performing surgical procedures in maxillary molar region may invariably lead to sinus perforation if one is not care full. \u0000Keywords: Cone beam computerized tomography, Dental implant, Maxillary sinus, Molar","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81200191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Gallstone disease and Non-Alcoholic Fatty Liver Disease (NAFLD) share common etiological pathways. The objective of this study was to determine the frequency of Gallstones and Non-Alcoholic Fatty Liver disease (NAFLD) in patients undergoing abdominal ultrasounds in our hospital and to compare the frequency of Gallstone disease in patients with NAFLD and without NAFLD. Methodology: This cross-sectional study was carried out at HBS General Hospital, Islamabad from January 2020 till December 2020. Patients undergoing routine ultrasounds in the out-patient department of the hospital were included in the study. Patients having Emergency Ultrasounds, history of Alcohol intake, history of chronic liver disease and pregnant patients were excluded from the study. Data was analysed using Microsoft Excel 2016 and IBM SPSS 22. Results: A total of 689 patients were included with a 3:1 Female to Male ratio. Mean Age was 40.65± 15.610 years. The prevalence of Gallstone disease was found to be 20.9% while that of NAFLD 27.6%. A higher percentage of patients with NAFLD had Gallstones as compared to those who did not have NAFLD (24.2% vs 19.6% respectively) however for overall data, statistical significance was not reached. A statistically significant greater number of young patients with NAFLD had Gallstones as compared to those who did not have NAFLD (50% vs 6%, p<0.001). Mean age was greater in patients who had NAFLD as well as those having Gallstones. Conclusion: The frequency of Gallstones was greater in patients with NAFLD as compared to those without NAFLD. Keywords: Cholelithiasis, Fatty Liver Disease, Gallstones, Non-Alcoholic, Ultrasonogram
背景:胆结石病和非酒精性脂肪性肝病(NAFLD)具有共同的病因途径。本研究的目的是确定在我院接受腹部超声检查的患者胆结石和非酒精性脂肪性肝病(NAFLD)的频率，并比较有NAFLD和无NAFLD患者胆结石疾病的频率。方法:本横断面研究于2020年1月至2020年12月在伊斯兰堡HBS总医院进行。在医院门诊部接受常规超声检查的患者被纳入研究。有急诊超声检查、有酒精摄入史、有慢性肝病史和怀孕的患者被排除在研究之外。数据分析采用Microsoft Excel 2016和IBM SPSS 22。结果:共纳入689例患者，男女比例为3:1。平均年龄40.65±15.610岁。胆结石患病率为20.9%，NAFLD患病率为27.6%。与非NAFLD患者相比，NAFLD患者有胆结石的比例更高(分别为24.2%和19.6%)，但总体数据没有达到统计学意义。与未患NAFLD的年轻患者相比，患有胆结石的年轻患者数量有统计学意义(50% vs 6%， p<0.001)。NAFLD患者和胆结石患者的平均年龄更大。结论:NAFLD患者胆囊结石发生率高于非NAFLD患者。关键词:胆石症，脂肪肝，胆结石，非酒精性，超声
{"title":"Frequency of Gallstones in Fatty Liver disease in a Tertiary Care of Suburban Islamabad","authors":"Iftikhar Ahmed, Arslan Zahid, Nauman Mustafa, Iram Iqbal, Asma Bibi, Fauzia Rashid, Shabir Rana, Tariq Nawaz","doi":"10.35787/jimdc.v12i1.857","DOIUrl":"https://doi.org/10.35787/jimdc.v12i1.857","url":null,"abstract":"Background: Gallstone disease and Non-Alcoholic Fatty Liver Disease (NAFLD) share common etiological pathways. The objective of this study was to determine the frequency of Gallstones and Non-Alcoholic Fatty Liver disease (NAFLD) in patients undergoing abdominal ultrasounds in our hospital and to compare the frequency of Gallstone disease in patients with NAFLD and without NAFLD. \u0000Methodology: This cross-sectional study was carried out at HBS General Hospital, Islamabad from January 2020 till December 2020. Patients undergoing routine ultrasounds in the out-patient department of the hospital were included in the study. Patients having Emergency Ultrasounds, history of Alcohol intake, history of chronic liver disease and pregnant patients were excluded from the study. Data was analysed using Microsoft Excel 2016 and IBM SPSS 22. \u0000Results: A total of 689 patients were included with a 3:1 Female to Male ratio. Mean Age was 40.65± 15.610 years. The prevalence of Gallstone disease was found to be 20.9% while that of NAFLD 27.6%. A higher percentage of patients with NAFLD had Gallstones as compared to those who did not have NAFLD (24.2% vs 19.6% respectively) however for overall data, statistical significance was not reached. A statistically significant greater number of young patients with NAFLD had Gallstones as compared to those who did not have NAFLD (50% vs 6%, p<0.001). Mean age was greater in patients who had NAFLD as well as those having Gallstones. \u0000Conclusion: The frequency of Gallstones was greater in patients with NAFLD as compared to those without NAFLD. \u0000Keywords: Cholelithiasis, Fatty Liver Disease, Gallstones, Non-Alcoholic, Ultrasonogram \u0000 ","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79637515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.35787/jimdc.v12i1.923
N. Nabi, A. Khattak, Summaya Sohail Chaudry
Rhabdomyosarcoma is the most common pediatric malignancy with a predilection for head and neck region. Embryonal Rhabdomyosarcoma is a variant of rhabdomyosarcoma which is extremely rare in middle ear. We present a case of middle year embryonal rhabdomyosarcoma in a five-year-old child who was treated as otitis media on first presentation and later misdiagnosed as a vascular aural polyp on histopathology.
{"title":"Middle Ear Embryonal Rhabdomyosarcoma in a Five Years Old Child - A Rare Case Report","authors":"N. Nabi, A. Khattak, Summaya Sohail Chaudry","doi":"10.35787/jimdc.v12i1.923","DOIUrl":"https://doi.org/10.35787/jimdc.v12i1.923","url":null,"abstract":"Rhabdomyosarcoma is the most common pediatric malignancy with a predilection for head and neck region. Embryonal Rhabdomyosarcoma is a variant of rhabdomyosarcoma which is extremely rare in middle ear. We present a case of middle year embryonal rhabdomyosarcoma in a five-year-old child who was treated as otitis media on first presentation and later misdiagnosed as a vascular aural polyp on histopathology.","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82509588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.35787/jimdc.v12i1.896
Sajid Ali, Tariq Latif, Muhammad ali, Shazia perveen, Muhammad bilal shafiq, Muhammad abu bakr
Background: Testicular germ cell tumors are common solid organ malignancies in children with a survival rate of more than 90 %. This study aims to assess the predictors of relapse and survival in testicular germ cell tumors in children. Methodology: A retrospective review was conducted on children up to the age of 18-years from January 2010 to December 2020 with a diagnosis of primary testicular germ cell tumors. Factors related to relapse and survival like age, baseline levels of tumor markers in serum and on relapse, stage at diagnosis, histological type, tumor laterality & size of the tumor in testicular germ cell tumors were analyzed. The data was entered into SPSS version 20. Statistical significance was set at a p-value ≤0.05. Results: A total of 115 patients with a mean age of 5.42+ 1.54 years having testicular germ cell tumor were treated. Seventeen patients (14.7 %) had relapse of disease. Relapse was highest in patients with stage I disease (64.7 %). Yolk sac tumor was the most common pathology that was noted in twelve (70 %) patients. The most common site of relapse was the retroperitoneum (70 %). Age of patient, stage of disease, and lymphovascular invasion were significant predictors of relapse and survival in testicular germ cell tumors. Conclusion: Management of patients with testicular germ cell tumors requires standardized follow-up protocol for early detection and treatment of disease relapse. Complete surgical excision with meticulous control of the residual disease is critical to prevent disease relapse. Keywords: Chemotherapy, Children, Outcome, Relapse, Testicular Tumor
背景:睾丸生殖细胞瘤是儿童常见的实体器官恶性肿瘤，生存率超过90%。本研究旨在评估儿童睾丸生殖细胞肿瘤复发和生存的预测因素。方法:对2010年1月至2020年12月诊断为原发性睾丸生殖细胞肿瘤的18岁以下儿童进行回顾性研究。分析与复发和生存相关的因素，如年龄、血清和复发时肿瘤标志物基线水平、诊断分期、组织学类型、肿瘤侧边及肿瘤大小。数据输入SPSS version 20。p值≤0.05，差异有统计学意义。结果:共治疗115例睾丸生殖细胞瘤患者，平均年龄5.42+ 1.54岁。17例(14.7%)复发。复发在I期患者中最高(64.7%)。卵黄囊肿瘤是最常见的病理，在12例(70%)患者中被注意到。最常见的复发部位是腹膜后(70%)。患者年龄、疾病分期和淋巴血管浸润是睾丸生殖细胞肿瘤复发和生存的重要预测因素。结论:睾丸生殖细胞肿瘤患者的治疗需要规范化的随访方案，以便及早发现和治疗疾病复发。完整的手术切除和细致的控制残留的疾病是防止疾病复发的关键。关键词:化疗，儿童，预后，复发，睾丸肿瘤
{"title":"Predictors of Relapse and Survival in Testicular Germ cell Tumors in Children","authors":"Sajid Ali, Tariq Latif, Muhammad ali, Shazia perveen, Muhammad bilal shafiq, Muhammad abu bakr","doi":"10.35787/jimdc.v12i1.896","DOIUrl":"https://doi.org/10.35787/jimdc.v12i1.896","url":null,"abstract":"Background: Testicular germ cell tumors are common solid organ malignancies in children with a survival rate of more than 90 %. This study aims to assess the predictors of relapse and survival in testicular germ cell tumors in children. \u0000Methodology: A retrospective review was conducted on children up to the age of 18-years from January 2010 to December 2020 with a diagnosis of primary testicular germ cell tumors. Factors related to relapse and survival like age, baseline levels of tumor markers in serum and on relapse, stage at diagnosis, histological type, tumor laterality & size of the tumor in testicular germ cell tumors were analyzed. The data was entered into SPSS version 20. Statistical significance was set at a p-value ≤0.05. \u0000Results: A total of 115 patients with a mean age of 5.42+ 1.54 years having testicular germ cell tumor were treated. Seventeen patients (14.7 %) had relapse of disease. Relapse was highest in patients with stage I disease (64.7 %). Yolk sac tumor was the most common pathology that was noted in twelve (70 %) patients. The most common site of relapse was the retroperitoneum (70 %). Age of patient, stage of disease, and lymphovascular invasion were significant predictors of relapse and survival in testicular germ cell tumors. \u0000Conclusion: Management of patients with testicular germ cell tumors requires standardized follow-up protocol for early detection and treatment of disease relapse. Complete surgical excision with meticulous control of the residual disease is critical to prevent disease relapse. \u0000Keywords: Chemotherapy, Children, Outcome, Relapse, Testicular Tumor \u0000 \u0000 ","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82792893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.35787/jimdc.v12i1.946
M. Ullah, M. F. Murad, Adil Shafi War, Aqsa Adeel
Gallbladder stones impacted at neck of gallbladder can result in acute calculous cholecystitis with mucocele gallbladder. Laparoscopic cholecystectomy is performed in such cases as an emergency surgery. We present a case long gallbladder with mucocele formation that was managed by laparoscopic approach. The gallbladder removed was 27.8cm in length. This is the longest gallbladder removed by laparoscopic cholecystectomy in Pakistan so far. The patient had uneventful recovery.
{"title":"Large gallbladder Removed by Laparoscopic Cholecystectomy A Case report","authors":"M. Ullah, M. F. Murad, Adil Shafi War, Aqsa Adeel","doi":"10.35787/jimdc.v12i1.946","DOIUrl":"https://doi.org/10.35787/jimdc.v12i1.946","url":null,"abstract":"Gallbladder stones impacted at neck of gallbladder can result in acute calculous cholecystitis with mucocele gallbladder. Laparoscopic cholecystectomy is performed in such cases as an emergency surgery. We present a case long gallbladder with mucocele formation that was managed by laparoscopic approach. The gallbladder removed was 27.8cm in length. This is the longest gallbladder removed by laparoscopic cholecystectomy in Pakistan so far. The patient had uneventful recovery.","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78792811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.35787/jimdc.v12i1.839
Raisa Kausar, K. Janjua, Mainmoona Siddique, Gideon Victor
Background: Patient safety has emerged as a prime agenda over the past few decades to deliver safe care in increasingly complex service delivery. This study was set out to measure the factors associated with the safety attitudes of nurses. Methodology: This descriptive cross-sectional research was conducted from May 2017 to June 2018 in Shifa International Hospital, Islamabad. Nurses were invited to participate in the study. The safety attitude questionnaire was used for data collection. Data were analyzed using SPSS v23.0. Results: The response rate was 86%. Job satisfaction was high at 78.37±23.63 while stress recognition was low at 53.18±27.68. Nurses liked their job being a nurse 79.92±28.01 and workplace conditions 80.33±26.44. Whereas, hostile situations 48.92±34.95, the negative effect of fatigue 48.50±35.32, being held back to report patient problems 47.58±34.76 and discuss errors 45.42±34.79 were also highlighted. Safety attitudes were statistically significant high among intensive care nurses (P-Value < 0.05). Safety scores of nurses with longer job duration were high than those with lesser job duration. Teamwork was favorably correlated with safety climate, job satisfaction, perception of management, and working conditions (R > .466, P-Value < .01). Conclusion: There was a positive attitude of nurses toward patients’ safety with some areas of improvement. Keywords: Attitude, Nurse, Patient safety, Practice
{"title":"Factors Associated with Nurses’ Attitude towards Patient Safety Culture in an International Accredited Tertiary Care Hospital, Islamabad","authors":"Raisa Kausar, K. Janjua, Mainmoona Siddique, Gideon Victor","doi":"10.35787/jimdc.v12i1.839","DOIUrl":"https://doi.org/10.35787/jimdc.v12i1.839","url":null,"abstract":"Background: Patient safety has emerged as a prime agenda over the past few decades to deliver safe care in increasingly complex service delivery. This study was set out to measure the factors associated with the safety attitudes of nurses. \u0000Methodology: This descriptive cross-sectional research was conducted from May 2017 to June 2018 in Shifa International Hospital, Islamabad. Nurses were invited to participate in the study. The safety attitude questionnaire was used for data collection. Data were analyzed using SPSS v23.0. \u0000Results: The response rate was 86%. Job satisfaction was high at 78.37±23.63 while stress recognition was low at 53.18±27.68. Nurses liked their job being a nurse 79.92±28.01 and workplace conditions 80.33±26.44. Whereas, hostile situations 48.92±34.95, the negative effect of fatigue 48.50±35.32, being held back to report patient problems 47.58±34.76 and discuss errors 45.42±34.79 were also highlighted. Safety attitudes were statistically significant high among intensive care nurses (P-Value < 0.05). Safety scores of nurses with longer job duration were high than those with lesser job duration. Teamwork was favorably correlated with safety climate, job satisfaction, perception of management, and working conditions (R > .466, P-Value < .01). \u0000Conclusion: There was a positive attitude of nurses toward patients’ safety with some areas of improvement. \u0000Keywords: Attitude, Nurse, Patient safety, Practice","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77509212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.35787/jimdc.v12i1.869
Faiz Rasul, R. Saif, H. M. Jehangir, Zainab Rizvi, S. Wahid, Khurram Nadeem
Background: Biological behaviour of Odontogenic Keratocyst (OKC) is aggressiveness than others Odontogenic Cysts (OCs) like Dentigerous Cyst (DCs) and Periapical Cyst/Residual Cysts (RCs). The aim of the study was to determine clinicopathological features and expression of Ki-67 in Odontogenic Cysts of the oral cavity. Methodology: This cross-sectional study was conducted at de’Montmorency College of Dentistry (DCD from Feb, 2020 to Feb, 2022 after approval from Institutional Review Board (IRB) of DCD. A total 78 cases of OCs were collected from hospitals which are affiliated with the DCD. Routine lab process for Hematoxylin & Eosin and Immunohistochemistry was performed. Data entry and statistical analysis was carried out in SPSS 21. A Chi- square test was applied to observe the association between cyst and Ki-67. P value < 0.05 was taken as statistically significant. Results: Among total 78 cases the mean age was 25.08 ±14.5 years with an age range of 6-70 years. Most OCs (64.1%) were reported in males than females (35.89%). Most OCs were reported in mandible (56.4%. Ki-67 expression in OKC was high 7.7%, low in 76.9% and negative in 15.4%). Most of the DCs and RCs expressed low expression of Ki-67 (84.6% and 76.9% respectively). Conclusion: Most of the odontogenic cysts expressed low expression of Ki-67 while few cases of OKC and DC expressed high expression. Keywords: Dentigerous Cyst, Odontogenic Keratocyst, Immunohistochemistry, Ki-67, Odontogenic Cysts, Periapical Cyst, Radicular Cyst.
背景:牙源性角化囊肿(OKC)的生物学行为比其他牙源性囊肿(OCs)如牙源性囊肿(DCs)和根尖周囊肿/残留囊肿(RCs)更具侵袭性。本研究的目的是确定口腔牙源性囊肿的临床病理特征和Ki-67的表达。方法:经DCD机构审查委员会(IRB)批准，本横断面研究于2020年2月至2022年2月在de 'Montmorency College of Dentistry (DCD)进行。共有78例OCs病例从DCD附属医院收集。进行苏木精、伊红和免疫组织化学常规实验室检查。使用SPSS 21进行数据录入和统计分析。采用卡方检验观察囊肿与Ki-67之间的关系。P值< 0.05为差异有统计学意义。结果:78例患者平均年龄25.08±14.5岁，年龄范围6 ~ 70岁。男性居多(64.1%)，女性居多(35.89%)。大多数OCs发生在下颌骨(56.4%)。Ki-67在OKC中高表达(7.7%)，低表达(76.9%)，阴性(15.4%)。大多数dc和rc低表达Ki-67(分别为84.6%和76.9%)。结论:Ki-67在牙源性囊肿中表达低，在OKC和DC中表达高。关键词:牙源性囊肿，牙源性角化囊肿，免疫组织化学，Ki-67，牙源性囊肿，根尖周囊肿，根状囊肿
{"title":"Clinicopathological Features and Expression of Ki-67 in Odontogenic Keratocyst, Dentigerous Cyst and Radicular Cyst","authors":"Faiz Rasul, R. Saif, H. M. Jehangir, Zainab Rizvi, S. Wahid, Khurram Nadeem","doi":"10.35787/jimdc.v12i1.869","DOIUrl":"https://doi.org/10.35787/jimdc.v12i1.869","url":null,"abstract":"Background: Biological behaviour of Odontogenic Keratocyst (OKC) is aggressiveness than others Odontogenic Cysts (OCs) like Dentigerous Cyst (DCs) and Periapical Cyst/Residual Cysts (RCs). The aim of the study was to determine clinicopathological features and expression of Ki-67 in Odontogenic Cysts of the oral cavity. \u0000Methodology: This cross-sectional study was conducted at de’Montmorency College of Dentistry (DCD from Feb, 2020 to Feb, 2022 after approval from Institutional Review Board (IRB) of DCD. A total 78 cases of OCs were collected from hospitals which are affiliated with the DCD. Routine lab process for Hematoxylin & Eosin and Immunohistochemistry was performed. Data entry and statistical analysis was carried out in SPSS 21. A Chi- square test was applied to observe the association between cyst and Ki-67. P value < 0.05 was taken as statistically significant. \u0000Results: Among total 78 cases the mean age was 25.08 ±14.5 years with an age range of 6-70 years. Most OCs (64.1%) were reported in males than females (35.89%). Most OCs were reported in mandible (56.4%. Ki-67 expression in OKC was high 7.7%, low in 76.9% and negative in 15.4%). Most of the DCs and RCs expressed low expression of Ki-67 (84.6% and 76.9% respectively). \u0000Conclusion: Most of the odontogenic cysts expressed low expression of Ki-67 while few cases of OKC and DC expressed high expression. \u0000Keywords: Dentigerous Cyst, Odontogenic Keratocyst, Immunohistochemistry, Ki-67, Odontogenic Cysts, Periapical Cyst, Radicular Cyst.","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87287461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.35787/jimdc.v12i1.907
Sheeba Ishtiaq, Dr Sohail Anwar, Dr Amna Rehman, Dr Rajia Liaqat, Dr Kashif Butt
Background: Tumors that arise from neuroendocrine cells can present throughout the body, most commonly in the gastrointestinal tract and pulmonary systems. Neuroendocrine tumors (NETs) of the lungs account for about 25% of primary lung cancers, as well as 20–25% of primary NETs Objective: To analyze the immune-histochemical aspects of Neuro-endocrine Tumors and apprise the reactivity of various immune-histochemical markers. Methodology: This cross-sectional study was conducted in Pathology Department of Gulab Devi Hospital Lahore from January 2021 to December 2021. Total 112 patients with pulmonary NETs cases diagnosed with medical records patients data, clinical features and radiologic images were obtained and both genders with CT scan findings of lung mass were included in the study. Data was entered and analyzed in SPSS. Gender, diagnosis, techniques etc. were presented as frequency and percentage. Age was presented as mean and SD. Results: The mean age was 45.2+12.1 years. The age range between 20 to 60 years. There were 96(86%) male and 16(14%) female. Typical carcinoid was prevailing in young age group while small cell neuro-endocrine tumor was dominant in older patients. Most of the samples were collected using bronchial biopsy 86(77%), 18(16%) of the samples were collected by CT guided biopsy while 7(6%) were collected by ultrasound guided biopsy and 1(1%) by surgical resection. Patients were diagnosed as small cell lung carcinoma 96(86%), typical carcinoid was the second most common diagnosis 10(9%), large cell lung carcinoma was 4(3.0%) and atypical carcinoid tumor was seen in 2(2%) in cases. Conclusion: SCLC was found to be the predominant pulmonary NET. Chromogranin is less sensitive than synaptophysin, raised Ki67 and TTF1 demarcates SCLC from carcinoid particularly in minute biopsy with obscure morphology. Key words Immunohistochemistry, Neuroendocrine carcinoma, Small cell lung carcinoma.
{"title":"Immunohistochemical Approach to the Study of Pulmonary Neuroendocrine Tumors","authors":"Sheeba Ishtiaq, Dr Sohail Anwar, Dr Amna Rehman, Dr Rajia Liaqat, Dr Kashif Butt","doi":"10.35787/jimdc.v12i1.907","DOIUrl":"https://doi.org/10.35787/jimdc.v12i1.907","url":null,"abstract":" \u0000Background: Tumors that arise from neuroendocrine cells can present throughout the body, most commonly in the gastrointestinal tract and pulmonary systems. Neuroendocrine tumors (NETs) of the lungs account for about 25% of primary lung cancers, as well as 20–25% of primary NETs \u0000Objective: To analyze the immune-histochemical aspects of Neuro-endocrine Tumors and apprise the reactivity of various immune-histochemical markers. \u0000Methodology: This cross-sectional study was conducted in Pathology Department of Gulab Devi Hospital Lahore from January 2021 to December 2021. Total 112 patients with pulmonary NETs cases diagnosed with medical records patients data, clinical features and radiologic images were obtained and both genders with CT scan findings of lung mass were included in the study. Data was entered and analyzed in SPSS. Gender, diagnosis, techniques etc. were presented as frequency and percentage. Age was presented as mean and SD. \u0000Results: The mean age was 45.2+12.1 years. The age range between 20 to 60 years. There were 96(86%) male and 16(14%) female. Typical carcinoid was prevailing in young age group while small cell neuro-endocrine tumor was dominant in older patients. Most of the samples were collected using bronchial biopsy 86(77%), 18(16%) of the samples were collected by CT guided biopsy while 7(6%) were collected by ultrasound guided biopsy and 1(1%) by surgical resection. Patients were diagnosed as small cell lung carcinoma 96(86%), typical carcinoid was the second most common diagnosis 10(9%), large cell lung carcinoma was 4(3.0%) and atypical carcinoid tumor was seen in 2(2%) in cases. \u0000Conclusion: SCLC was found to be the predominant pulmonary NET. Chromogranin is less sensitive than synaptophysin, raised Ki67 and TTF1 demarcates SCLC from carcinoid particularly in minute biopsy with obscure morphology. \u0000Key words Immunohistochemistry, Neuroendocrine carcinoma, Small cell lung carcinoma.","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74001595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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