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Uji Perbandingan Penetapan Kadar Sediaan Tablet Allopurinol 300 mg Generik dengan Nama Dagang Beredar di Distrik Sentani, Jayapura
Pub Date : 2019-05-29 DOI: 10.31957/JBP.770
Rusnaeni Rusnaeni, E. S. Simaremare
Allupurinol is a medicine to treat gout especially to minimize the quantity of uric acid inside human blood. This study aims to understand the quality of gout drugs particularly the standard of Allupurinol between generic 300 mg and others Allupurinol tablet in retails at Jayapura Regency. Survey method has been used and samples were collected from Sentani district, Jayapura Regency. Spectrophotometer was used to determine the rate of Allupurinol. The results proved that in Allupurinol generic (A) the rate was 100.28% and generic (B) was 99.044%. For others tablet non generic with naming (a) the rate of Allupurinol as 99.46% while (b) was 100.77%. It means the averages of Allupurinol contain in generic was 99.6% and non-generic was 100.12%. According to Indonesian Farmakope Manual 4th Edition, the rate of Allupurinol contains in a drug must be 93.0% for minimum and can’t be more than 107.0%. Our study shown that Allupurinol generic with (A) label and non-generic with (b) label are based on the Indonesian Farmakope Standard 4th Edition.  Key words: Tablet Allopurinol, Penetapan generik, Jayapura.  
磺胺嘌呤醇是一种治疗痛风的药物,尤其能减少人体血液中的尿酸含量。本研究旨在了解痛风药物的质量,特别是在Jayapura Regency零售的300 mg仿制药和其他Allupurinol片剂之间的差异。采用调查方法,从查亚普拉县森塔尼区收集样本。用分光光度法测定绿嘌呤醇的收率。结果表明,绿嘌呤醇仿制药(A)的提取率为100.28%,仿制药(B)的提取率为99.044%。其他非仿制片剂(a)溶出率为99.46%,(b)溶出率为100.77%。即仿制药中铝尿醇的平均含量为99.6%,非仿制药中铝尿醇的平均含量为100.12%。根据印尼《农业手册》第4版规定,药品中Allupurinol的含量最低为93.0%,不能超过107.0%。我们的研究表明,具有(A)标签的Allupurinol仿制药和具有(b)标签的非仿制药基于印度尼西亚Farmakope标准第4版。【关键词】别嘌呤醇片剂;Penetapan generic;
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引用次数: 0
Berudu (Amphibia: Anura) di Taman Wisata Air Terjun (TWAT) Kembang Soka, Kulon Progo, Daerah Istimewa Yogyakarta Pada Musim Kemarau
Pub Date : 2019-05-29 DOI: 10.31957/JBP.616
Nishfi Laila Maghfiroh, Rury Eprilurahman
Kembang Soka Waterfall Tourism Park in Java, Indonesia, is a potential habitat for frogs and toads (Anurans), as it contains a wide variety of water sources. To date, research on the diversity of Anura in the park has been limited to adult individuals. As such, the diversity of larvae is unknown. This study aimed to determine the diversity of Anuran tadpoles and their habitat in Kembang Soka Waterfall Tourism Park. Several surveys were carried out during the dry season of July–October 2018, with a total of five breeding sites surveyed. Three species of tadpoles were recorded: Leptobrachium hasseltii, Limnonectes kuhlii, and Phrynoidis aspera. The tadpoles of L. hasseltii had the greatest abundance, and were found in almost all breeding sites. Conversely, the tadpoles of L. kuhlii and P. aspera were only found in two of the breeding sites.   Key words: tadpoles, diversity, dry season, Kembang Soka Waterfall Tourism Park.
印度尼西亚爪哇岛的肯邦索卡瀑布旅游公园是青蛙和蟾蜍(Anurans)的潜在栖息地,因为它包含各种各样的水源。迄今为止,对公园内无尾猿多样性的研究仅限于成年个体。因此,幼虫的多样性是未知的。本研究的目的是确定坎邦索卡瀑布旅游公园内阿努兰蝌蚪的多样性及其栖息地。在2018年7月至10月的旱季期间进行了几次调查,共调查了五个繁殖地。记录到3种蝌蚪:哈氏细臂蝌蚪(Leptobrachium hasseltii)、库氏细尾蝌蚪(Limnonectes kuhlii)和粗尾蝌蚪(Phrynoidis aspera)。哈苏莱的蝌蚪数量最多,几乎在所有的繁殖地都有发现。相反,kuhlii和P. aspera的蝌蚪只在两个繁殖地发现。关键词:蝌蚪,多样性,旱季,根邦索卡瀑布旅游公园
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引用次数: 1
Analisis Dimorfisme Kupu-Kupu Sayap Burung (Ornithoptera sp.) Endemik Papua
Pub Date : 2019-05-29 DOI: 10.31957/JBP.634
E. Warikar, E. R. Ramandey, Hendra K. Maury
Ornitophera sp. is one of the groups of butterflies endemic in Papua and West Papua provinces. The significant morphological differences between male and female butterflies (dimorphism) are in the shape, size and color of the wings. Morphological characteristics are important sources of information. Based on the results of specimen collections at the Papua Insect Collection Laboratory (KSP) Jayapura, there are several species from various locations in Papua. The variation in dimorphism is likely to occur in this species which gives rise to new sub-species. The purpose of this study was to record the dimorphism of the endemic Bird Wing of Papua which had been stored in the Papua Insect Collection Laboratory (KSP) Jayapura. The method used is a direct measurement of the morphology of bird wing butterfly specimens stored in the KSP Laboratory, Cenderawasih University. Morphometric data were analyzed using the SPSS 20 and Multi Variate Statistical Package (MVSP 3.1) programs. The results obtained were 7 Ornithoptera species stored in the KSP Jayapura Laboratory, namely O. chiamera, O. goliath, O. meridionalis, O. paradisea, O. priamus, O. thitonus and O. rothschildi. Based on observations there are striking differences in color, shape and size between male and female in the same species.   Key words: birdwing butterfly, Ornithoptera sp., KSP Jayapura, dimorphisme.  
Ornitophera sp.是巴布亚省和西巴布亚省特有的蝴蝶群之一。雌雄蝴蝶在形态上的显著差异(二态性)在于翅膀的形状、大小和颜色。形态特征是重要的信息来源。根据巴布亚昆虫收集实验室(KSP)查亚普拉的标本收集结果,有几个物种来自巴布亚的不同地点。二态性的变异很可能发生在这个物种中,从而产生新的亚种。本研究的目的是记录保存在巴布亚昆虫收集实验室(KSP)查亚普拉的巴布亚特有鸟翅的二态性。所使用的方法是直接测量储存在肯德拉瓦西大学KSP实验室的鸟翼蝴蝶标本的形态。使用SPSS 20和Multi - Variate Statistical Package (MVSP 3.1)程序对形态计量学数据进行分析。结果获得了KSP Jayapura实验室保存的7种鸟翅目,分别是O. chiamera、O. goliath、O. meridionalis、O. paradisea、O. priamus、O. thitonus和O. rothschild。根据观察,同一物种的雄性和雌性在颜色、形状和大小上存在显著差异。关键词:鸟翅蝶;鸟翅目;查亚普拉;
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引用次数: 1
Skrining Senyawa Kimia dan Uji Aktivitas Sitotoksik Ekstrak Etanol Teripang Kridou Bintik (Bohadschia argus Jeager) Asal Pantai Harlem Kabupaten Jayapura, Papua
Pub Date : 2019-05-29 DOI: 10.31957/JBP.633
Apianus Kilungga, L. Y. Chrystomo, Puguh Sujarta
The Bohadschia argus Jeager contains bioactive compounds that have the potential as antibiotics, antibacterial, antitumor, anticoagulants and anesthetics and alleviate cancer. This study aims to determine the content of chemical compounds group and to test the cytotoxic activity of ethanol extract of Bohadschia argus Jeager. The method for determining the group of chemical compounds was used the color reaction and precipitation using chemical reagents. The method for testing cytotoxic activity using the Brine Shimp Lethality Test (BSLT), this method commonly was used to test the safety of the use of natural ingredients as traditional medicine. The results of screening of the chemical compound group of  Bohadschia argus Jeager extract showed that the extract contained a lot of alkaloids secondary metabolites and few saponins. The results of testing of cytotoxic activity showed LC50 value of 878.22 ppm. Base on the results of this study it can be concluded that the ethanol extract of Bohadschia argus Jeager has significant cytotoxic activity against Artemia salina Leach, so it can be considered as a chemotherapeutic agent.   Key words: Screening, chemical compounds, ethanol extract, B. argus, BSLT. 
Bohadschia argus Jeager含有生物活性化合物,具有抗生素、抗菌、抗肿瘤、抗凝血剂和麻醉剂的潜力,并能缓解癌症。本研究旨在测定大鲵乙醇提取物中化合物基团的含量,并检测其细胞毒活性。采用显色反应和化学试剂沉淀法测定化合物的基团。使用盐水致死试验(BSLT)测试细胞毒性活性的方法,该方法通常用于测试天然成分作为传统药物使用的安全性。结果表明,该提取物中含有较多的生物碱次生代谢产物,皂苷含量较少。细胞毒活性检测结果显示LC50值为878.22 ppm。根据本研究结果,可以得出结论,Bohadschia argus Jeager乙醇提取物对Artemia salina Leach具有显著的细胞毒活性,可以考虑作为一种化疗药物。关键词:筛选;化合物;乙醇提取物;
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引用次数: 3
Isolasi dan Uji Patogenitas Isolat Fungi Entomopatogen Terhadap Stadium Dewasa Nyamuk Aedes aegypti 昆虫真菌菌丝与埃及伊蚊发育中的成虫的分离和病原检验
Pub Date : 2019-05-29 DOI: 10.31957/JBP.832
Supiyanto Supiyanto, Emantis Rosa, B. Irawan, Nismah Nukmal
This research aims to determine the effectiveness of four types of entomopathogenic fungi isolated from Ae. aegypti mosquitoes from Bandar Lampung to the mortality of adult stages of Ae. aegypti mosquitoes. This research was conducted in October 2018-January 2019 at the Microbiology Laboratory of FMIPA, University of Lampung. This research using factorial completely randomized design with two factor treatment. The first factor is type of isolate (Mucor sp., Penicillium sp., IL3 (unidentified), Aspergillus sp.) and second faktor is dilution (control, 10 (without dilution), 10-1, 10-2, 10-3). Data were analyzed using ANOVA. If there are significant differences, then it is continued by the Duncan Test at the level of 5%. The results showed that the four types of fungi (Mucor sp., Penicillium sp., Aspergillus sp. and IL3) were able to cause mortality of Ae. aegypti mosquitoes with the highest killing power was  in Mucor sp. 10 (without dilution) is 43.33%. But the most effective is Mucor sp. 10-3 because the highest dilution has been able to cause mosquito mortality by 30%.  Key words: Ae. aegypti, DHF, entomopathogenic fungi, isolate, dilution. 
本研究旨在确定从白纹伊蚊中分离的四种昆虫病原真菌的有效性。南榜港埃及伊蚊成虫期的死亡率。蚊。该研究于2018年10月至2019年1月在楠榜大学FMIPA微生物实验室进行。本研究采用因子完全随机设计,双因素处理。第一个因素是分离物的类型(Mucor sp., Penicillium sp., IL3(未知),Aspergillus sp.),第二个因素是稀释度(对照,10(未稀释),10- 1,10 - 2,10 -3)。数据分析采用方差分析。如果存在显著差异,则在5%的水平上继续进行邓肯测试。结果表明,4种真菌(Mucor sp.、Penicillium sp.、Aspergillus sp.和IL3)均能引起伊蚊死亡。埃及伊蚊杀灭力最高的品种为毛霉菌10号(未稀释),为43.33%;但最有效的是毛霉菌sp. 10-3,因为最高稀释度可以使蚊子死亡率降低30%。关键词:Ae;埃及伊蚊,DHF,昆虫病原真菌,分离物,稀释。
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引用次数: 2
A new record of Vaccinium carneolum (Ericaceae) in Indonesian New Guinea 文章题目印度尼西亚-新几内亚石楠属新记录
Pub Date : 2019-05-29 DOI: 10.31957/JBP.479
W. Mustaqim
Vaccinium carneolum (Ericaceae), previously known only from Papua New Guinea, has been recently collected from Arfak Mountains, Papua Barat Province. It represents the first record of this species in Indonesian New Guinea. A description and illustration, as well as a brief discussion, are provided.Key words: Ericaceae, New Guinea, Plant taxonomy. 
以前只在巴布亚新几内亚发现的石蜡(石蜡科),最近在巴布亚巴拉特省Arfak山采集到。这是该物种在印尼新几内亚的首次记录。提供了描述和说明,以及简短的讨论。关键词:Ericaceae,新几内亚,植物分类
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引用次数: 0
Ekologi dan Kelimpahan Ikan Sentani Gudgeon (Oxyeleotris heterodon, Weber 1908) dan Snakehead Gudgeon (Giuris margaritacea, Valenciennes 1837) di Danau Sentani, Papua
Pub Date : 2019-05-29 DOI: 10.31957/JBP.646
Henderite L. Ohee, Gerardinalia Ngamelubun, Joane J. Ansaka, Novela H. Korwa, Puguh Sujarta
Freshwater community in Lake Sentani comprise of 35 species including three endemic species, seven native species, eight anadromous fish and 17 introduced species. Two native species are Sentani Gudgeon (Oxyeleotris heterodon) and Snakehead Gudgeon (Giuris margaritacea). The survey aims to document the ecology and fish abundance of the gudgeons in Lake Sentani. Fish sampling was done passively by using gill nets with three different mesh sizes in five locations; Puai, Enandowai, Waena, Ayapo and Yahim. Substrate type, water vegetations, habitat depth and fish abundance were recorded each locations. Substrate preferences of the gudgeons are sand, mud and gravel, while O. heterodon was more abundance in sand mud substrate type. Moreover, water vegetation preference was different between O. heterodon and G. margaritacea. Sentani Gudgeon prefer habitat with dense water vegetations, while G. margaritaceus could be found in habitat with or without water vegetation. Theses two gudgeons were found in relatively the same habitat depth, up to 7 meters depth. O. heterodon and G. margaritacea had a very low abundance in the lake. It is important to conserve lake area from the edge  up to 7 meter depth that consist of sand, mud and gravel substrate types and dense water vegetation to ensure the population of these two gudgeons are abundance in Lake Sentani.   Key words: Ecology, Lake Sentani, relative abundance, O. heterodon, G. margaritacea.
森塔尼湖的淡水群落共有35种,包括3种特有种、7种本地种、8种溯河鱼类和17种引进物种。两种本地种是尖尾鲟(Oxyeleotris heterodon)和蛇头鲟(Giuris margaritacea)。这次调查的目的是记录森塔尼湖的生态和鱼类丰度。在五个地点使用三种不同网目大小的刺网进行被动取样;普埃、埃南多瓦、瓦埃纳、阿亚波和亚希姆。记录了各地点的基质类型、水域植被、生境深度和鱼类丰度。基材类型以砂、泥、砾石为主,而沙泥基材类型以异齿石居多。此外,异花草和玛格丽塔草对水体植被的偏好存在差异。小黄鸡喜水植被茂密的生境,玛格丽塔花喜无水植被的生境。这两种坚鸠是在相对相同的栖息地深度发现的,深度都在7米以下。异齿藻和玛格丽塔花在湖中的丰度很低。重要的是要保护从边缘到7米深的湖泊区域,包括沙,泥和砾石基质类型和茂密的水生植被,以确保这两种鸽子在森塔尼湖的数量丰富。关键词:生态学;森塔尼湖;相对丰度;
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引用次数: 1
Uji bakteriologis air di PDAM GT Kabupaten Magelang dengan metode MPN Quanty-Tray 马格朗县PDAM GT的水菌检验与MPN Quanty-Tray方法
Pub Date : 2019-05-29 DOI: 10.31957/JBP.747
Lailatul Mubarokhah, W. Wijanarka
Water is the main need for life. The bacteriological requirements for clean water are the presence or absence of Coliform bacteria and E. coli in water. The purpose of this study was to determine the quality of water from gravity springs and pump springs as a source of water in Magelang Regency PDAM GT and Magelang Regency community. This study was to finding out the bacteriological test of water in Magelang Regency PGT. This study was to know bacteriological water testing techniques using the MPN Quanti-method Tray in Magelang Regency PGT. The method used in this study is the Quanty-Tray Most Probable Number (MPN) method. The sample of this study were two gravitational springs namely Sample A and Sample B and two pumping springs namely Sample C and Sample D. The results of MPN calculations from the four springs did not meet the requirements of clean water ready to be distributed to the community because Coliform in the spring gravity water and pumps and found E. coli in the pump spring water.   Key words: coliform, MPN quanty-tray, bacteriological requirement.
水是生命的主要必需品。对净水的细菌学要求是水中大肠菌群和大肠杆菌的存在与否。本研究的目的是确定重力泉和泵泉作为马格朗摄制区PDAM GT和马格朗摄制区水源的水质。本研究旨在了解马格朗县自来水厂水质的细菌学检测方法。本研究是了解在马格朗县PGT使用MPN定量法托盘的细菌学水检测技术。本研究使用的方法是数量-托盘最可能数(MPN)法。本研究的样本为两个重力泉A和B,以及两个抽水泉C和d。由于重力泉和抽水泉中存在大肠菌群,而抽水泉中发现大肠杆菌,这四个抽水泉的MPN计算结果不符合准备分发给社区的清洁水的要求。关键词:大肠菌群;MPN定量盘;细菌学要求
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引用次数: 0
Keanekaragaman Anggrek (Orchidaceae) di Taman Wisata Alam Sorong, Kota Sorong, Papua Barat 西巴布亚索朗市苍龙自然公园的兰花多样性
Pub Date : 2018-12-24 DOI: 10.31957/JBP.492
Reza Saputra, Djefry Tibalia, Fajar Darwis, Akbar Sumirto
Orchid diversity studies have been conducted at the Sorong Nature Park, Sorong City, West Papua. There are 84 collection numbers consisting of 69 epiphytic orchids, 14 terrestrial orchids, and 1 holomycotrophic orchid. This number belongs to 34 genera and 84 species, which are native species with at least 36 endemic species.  Dendrobium, Bulbophyllum, and Taeniophyllum are the three genera with the highest numbers of species. Key words: Orchid, Diversity, Sorong National Park, West Papua. 
兰花多样性研究在西巴布亚索隆市的索隆自然公园进行。共有84个收藏号,其中附生兰69种,陆生兰14种,全菌养兰1种。其中本地种34属84种,特有种至少36种。石斛属、球叶属和带叶属是种数最多的三个属。关键词:兰花,多样性,索龙国家公园,西巴布亚
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引用次数: 3
Record of Animals Association with Xanthostemon novoguineensis (Valeton) novoguineensis (Valeton)与黄茎(Xanthostemon novoguineensis)关联记录
Pub Date : 2018-12-24 DOI: 10.31957/jbp.610
R. C. Sanito
Xanthostemon novoguineenis (vernacular name: Sowang), an endemic plant in Papua from Myrtaceae family, is found widely near the buffer zone area and Mt. Cyclops Nature Reserve (MCNR) area. This research aimed to record the association of animals towards X. novoguineensis on its natural habitat. The survey was conducted in Cyclops buffer zone near Sentani City, Papua Province, Indonesia. The result showed that an interaction of animals directly to X. novoguineensis was documented and identified. Some insects species have an association with X. novoguineensis, namely black wasp (Isodontia sp 1), black-orange wasp (Isodontia sp 2), red weaver ant (Oecophylla sp 1) and black weaver ant (Oecophylla sp 2) have an association directly to flowers of X. novoguineensis. Furthermore, stick insect (Scepthrophasma sp) and spider (possibly from Araneae family) have an association with the leaves and trunks of this plant. Based on the finding, some leaves of these plant are fed by insects. It is indicated by a pattern of insect bites on the leaves.  Key words: buffer zone area,  cyclops, insect, sowang, Papua
Xanthostemon novoguineis(本地名:Sowang)是巴布亚特有植物,属桃金娘科,广泛分布于缓冲区和Cyclops山自然保护区(MCNR)附近。本研究旨在记录动物与诺沃几内亚蠓自然栖息地的关系。该调查是在印度尼西亚巴布亚省森塔尼市附近的Cyclops缓冲区进行的。结果表明,动物与诺沃几内亚弧菌有直接的相互作用。一些昆虫物种与新几内亚棘虫有亲缘关系,即黑黄蜂(Isodontia sp 1)、黑橙黄蜂(Isodontia sp 2)、红织蚁(Oecophylla sp 1)和黑织蚁(Oecophylla sp 2)与新几内亚棘虫的花有直接亲缘关系。此外,竹节虫(Scepthrophasma sp)和蜘蛛(可能属于蜘蛛科)与该植物的叶片和树干有关联。根据这一发现,这些植物的一些叶子是由昆虫喂养的。从树叶上昆虫叮咬的痕迹可以看出。关键词:缓冲区;独眼虫;昆虫
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引用次数: 0
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