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Electrocardiogram of Obese Young Adults in a University, Malaysia 马来西亚一所大学中肥胖年轻人的心电图
Pub Date : 2019-06-15 DOI: 10.57002/jms.v17i1.257
A. A. Myat, Nur Izzati Aqilah Bt Mt Sariman, Najihah Mohd Bisri, R. Devendran
Background and Aim: Obesity exhibits wide variety of electrocardiogram (ECG) abnormalities in adults. Previous researches have found different results since they tested mostly on children, adolescents, and middle aged persons. However, there’s no clear evidence of the association between obesity and ECG variables, especially in young adults. Hence, the aim of this research is to compare ECG parameters (PR interval, QRS interval, corrected QT, axis and height of P and R wave) of obese with normal BMI young adults.Materials and method: A cross-sectional observational study was done on 38 students of a private university in Shah Alam. They were aged between 20 to 30 years, involving normal and obese persons. Anthropometric data, arterial blood pressure and standard 12-lead ECGs were collected for every participant. Independent-sample t-tests and non-parametric Mann-Whitney test were conducted to compare data of normal persons and obese persons. Pearson correlation was done to correlate ECG parameters with BMI, Weight and systolic arterial blood pressure.Results: Heart rate, PR interval, QRS interval and QT interval of obese person were not significantly different from normal. Height of R wave in obese person is more than that of normal person (P<0.05). However, there was no correlation between BMI, Weight, systolic blood pressure and ECG parameters that could be found.Conclusion: Thus, ECG wave and intervals except height of the R wave of obese young adults are not significantly different from those of the normal BMI. Finding of higher R wave in obese groups indicates ventricle wall of obese young adults are thicker than that of the young adults with normal BMI and it is not related to the effect of systolic arterial blood pressure, BMI and even weight of the person
背景与目的:肥胖在成人中表现出各种各样的心电图异常。此前的研究主要以儿童、青少年、中年人为对象,因此得出了不同的结果。然而,没有明确的证据表明肥胖和心电图变量之间存在关联,尤其是在年轻人中。因此,本研究的目的是比较肥胖与正常BMI青年的心电图参数(PR间期、QRS间期、校正QT间期、P波和R波轴和高度)。材料和方法:对沙阿南一所私立大学的38名学生进行了横断面观察研究。他们的年龄在20到30岁之间,包括正常人和肥胖者。收集每位参与者的人体测量数据、动脉血压和标准12导联心电图。采用独立样本t检验和非参数Mann-Whitney检验比较正常人和肥胖者的数据。将心电图参数与BMI、体重和收缩压进行Pearson相关性分析。结果:肥胖者心率、PR间期、QRS间期、QT间期与正常人无显著差异。肥胖者R波高度高于正常人(P<0.05)。然而,BMI、体重、收缩压和心电图参数之间没有相关性。结论:由此可见,肥胖青年的心电图波及间隔除R波高度外与正常BMI无显著差异。肥胖组R波较高,说明肥胖青壮年脑室壁比BMI正常的青壮年脑室壁厚,与收缩压、BMI甚至体重的影响无关
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引用次数: 0
Creating effective awareness campaign on the importance of martial arts among youth 在青少年中开展有效的宣传活动,宣传武术的重要性
Pub Date : 2019-06-15 DOI: 10.57002/jms.v17i1.255
Muhammad Bin Hasnan, Rusyaizila Ramli, Safinaz Mustapha
Bullying tends to happen most often in and around the school, specifically in the areas where adult supervision is little or none at all. Campaigns on bully awareness is proven unsuccessful considering the situation has been going on and keep happening. This also due to the lack of firm and indecisive action against the bully. This research will focus on encouraging the victims to participate and learn how to defend themselves against bully. By learning martial arts, the victim will be able to defend themselves independently and stop putting hopes for others to do so in their rights. The objective of this marketing campaign is to encourage the bully victims to learn martial arts in order to defend themselves. The promotional marketing items that will be distributed along with the campaign shall explain the benefits of learning martial arts and where they can sign up for the courses. The concept and design theme for the promotional items will be made suitable and appealing for the target audiences. An attractive publishing is proved effective as a promotional items since it has the ability to persuade and pique the interest of the victims in learning how to defend themselves against bully. This, in hope will slowly but surely reduce the frequency of bully.
欺凌往往发生在学校及其周围,特别是在成人监督很少或根本没有监督的地区。考虑到这种情况一直在发生,提高欺凌意识的运动被证明是不成功的。这也是由于对恶霸缺乏坚定和优柔寡断的行动。这项研究将侧重于鼓励受害者参与并学习如何保护自己免受欺凌。通过学习武术,受害者将能够独立地为自己辩护,而不再寄希望于别人在他们的权利中这样做。这一营销活动的目的是鼓励欺凌受害者学习武术,以保护自己。与活动一起分发的促销营销项目应解释学习武术的好处以及他们可以在哪里报名参加课程。推广项目的概念和设计主题将切合目标受众的需要。一个有吸引力的出版物被证明是有效的促销项目,因为它有能力说服和激起受害者学习如何保护自己免受欺凌的兴趣。希望这将缓慢但肯定地减少欺凌的频率。
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引用次数: 0
Rapid Biogenic and Uv-Vis Spectroscopic Study of Silver Nanoparticle Synthesis by Methanolic Extract of Piper Species 胡椒醇提物合成纳米银的快速生物源及紫外可见光谱研究
Pub Date : 2019-06-15 DOI: 10.57002/jms.v17i1.260
N. Nasrudin, Shanthriga V, Marini Ab. Rahman
Nanotechnology is one of the most developing areas which involve utilization of materials with structural dimension in of 1-100 nm. This technology opened a pathway for the synthesis of silver nanoparticle by various physical and chemical methods. The biosynthesis method from plant extracts are considered as alternative as it is relatively simple, nontoxic, and environmentally friendly methods. The objective was to synthesize and characterize silver nanoparticle via ultraviolet visible spectroscopy of silver nanoparticles from three piper species which are Piper nigrum, Piper sarmentosum and Piper betel. Silver nanoparticles were prepared by the reaction of 1 mM of 90 ml silver nitrate and 10 ml methanolic leaf extract of each type of plant that act as reductant and stabilizer. The synthesized nanoparticle was characterized by color changes from green into dark brown with increasing intensity of the color from 10 minutes until 48 hour indicating the completion of silver nanoparticle formation at 48 hour. A UV–Vis spectrum of the methanolic medium containing silver nanoparticles demonstrated a peak at 413 nm, 417 nm and 420 nm for Piper nigrum, Piper sarmentosum and Piper betel respectively that corresponds to the plasmon absorbance of silver nanoparticles. The maximum percentage increase in the rate of absorbance was found specifically at 24 hour in all the three leaf. In conclusion piper species is a source for synthesizing silver nanoparticles and Piper nigrum being an excellent source for the synthesis due to the narrow, sharp peak and showing maximum percentage increase at 24 hour among all the three plants. This study exhibited the potential of three methanolic extract of piper species for the green synthesis of silver nanoparticles.
纳米技术是目前发展最快的领域之一,它涉及到结构尺寸在1-100纳米之间的材料的利用。该技术为多种物理化学方法合成纳米银开辟了新的途径。从植物提取物中提取的生物合成方法被认为是一种替代方法,因为它相对简单、无毒、环保。目的是利用紫外可见光谱对三种胡椒(胡椒、沙门托胡椒和槟榔)中银纳米粒子进行合成和表征。以90 ml硝酸银和10 ml甲醇叶提取物分别作为还原剂和稳定剂,制备纳米银颗粒。从10分钟到48小时,合成的纳米颗粒的颜色从绿色变为深棕色,颜色的强度增加,表明在48小时内完成了银纳米颗粒的形成。对含银纳米粒子的甲醇介质进行紫外可见光谱分析,发现黑椒、沙薄荷椒和槟榔分别在413 nm、417 nm和420 nm处出现峰值,对应于银纳米粒子的等离子体吸光度。三片叶片吸光度的最大增幅均出现在24 h。综上所述,胡椒属植物是合成纳米银粒子的最佳来源,而胡椒属植物在24 h时的峰值窄而尖,且百分比增幅最大,是合成纳米银粒子的最佳来源。本研究显示了三种胡椒的甲醇提取物在绿色合成纳米银方面的潜力。
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引用次数: 1
Identification of Bloodstains on Different Fabrics after Washing with Commonly Used Detergent in Malaysia 马来西亚常用洗涤剂洗涤后不同织物上血迹的鉴定
Pub Date : 2019-06-15 DOI: 10.57002/jms.v17i1.258
Sharifah Mastura Syed Mohd Daud, S. Sundram
Bloodstains as physical and biological evidence encountered in number of crimes will provide vital information to define a type of crime and link a suspect to the scene of a crime. This research will enlighten the identification of bloodstain on different types of fabrics which were washed with detergents prior to applying Kastle-Meyer (KM) tests. All six types of fabric were stained with blood and soaked in commonly used detergents in Malaysia for a various soaking time. It is found that Dynamo detergent shows the highest percentage in removing the bloodstain from all those six fabrics. Besides, soaking time interval of 60 minutes in all detergent showed the maximum removal of bloodstains compared to 20 minutes which has minimal ability to remove bloodstains. Among all the fabrics, cotton showed the maximum percentage of bloodstain retention after washing with all the detergent. The finding of the study would help forensic investigator to trace invisible bloodstain such as in washed clothing in order to solve the crimes.
血迹作为在许多犯罪中遇到的物证和生物证,将为确定犯罪类型和将嫌疑人与犯罪现场联系起来提供重要信息。这项研究将启发鉴定不同类型织物上的血迹,这些织物在应用卡斯尔-迈耶(KM)试验之前用洗涤剂洗涤。所有六种织物都沾上了血迹,并在马来西亚常用的洗涤剂中浸泡了不同的浸泡时间。结果表明,Dynamo洗涤剂对6种织物的血迹去除率最高。此外,所有洗涤剂的浸泡时间间隔为60分钟,对血迹的去除效果最大,而浸泡时间间隔为20分钟,对血迹的去除效果最小。在所有织物中,用所有洗涤剂洗涤后,棉的血迹保留率最高。该研究结果将有助于法医调查人员追踪洗过的衣服等看不见的血迹,从而破案。
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引用次数: 1
Correlation between Haemoglobin Concentration and Malondialdehyde Level in Healthy Middle Age Adults 健康中年人血红蛋白浓度与丙二醛水平的相关性
Pub Date : 2019-06-15 DOI: 10.57002/jms.v17i1.254
A. A. Myat, Tuan Sharifah Ainur Hidayah Binti Tuan Zaki, Najihah Mohd Bisri, M. R. Alwan, Hasanian Faisal Ghazi, R. Devendran, Aniruddha Bhattacharjee
Background and Aims: In every disease, there will be the triggers on the occurrences. One of them is the oxidative stress, an imbalance between free radicals such as reactive oxygen species (ROS) and the antioxidants. The human body manages free radicals through neutralization by the antioxidative defense mechanism, however, when excessive free radicals being produced, it will become less effective. Over 40 years of age, oxidative stress become prominent and may associated with many diseases such as neural disorders and cardiovascular diseases. Oxidative stress can cause damage to lipids, known as lipid peroxidation, producing malondialdehyde (MDA), a marker to detect the degree of oxidative stress. Availability of oxygen (O2) is the main factor of the ROS formation, which could be indicated by haemoglobin (Hb) concentration. Thus, this research is conducted to find out the correlation between Hb concentration and MDA level in healthy middle age adults.Methods: A correlation study was conducted in a private University, Shah Alam from January 2018 until March 2018. Total 16 participants, who are MSU staffs, age between 45 and 65, with no known diseases, are selected after the consents are gained. Pearson correlation was used for statistical analysis of the data.Results: It is found that there is a strong correlation between Hb concentration and MDA level (r: .756, p <0.001). This means that MDA production is significantly increased when the Hb concentration is increased.Conclusion: The MDA level is strongly correlate with the Hb concentration in the middle age apparently healthy adults. It can be postulated that MDA production correlates with oxygen availability at the intracellular respiration in normal middle aged person
背景和目的:每一种疾病的发生都有其触发因素。其中之一是氧化应激,即自由基如活性氧(ROS)和抗氧化剂之间的不平衡。人体通过抗氧化防御机制来中和自由基,但当自由基产生过多时,其作用就会减弱。超过40岁,氧化应激变得突出,并可能与许多疾病有关,如神经障碍和心血管疾病。氧化应激可引起脂质损伤,即脂质过氧化,产生丙二醛(MDA),这是检测氧化应激程度的标志。氧的可用性(O2)是ROS形成的主要因素,这可以通过血红蛋白(Hb)浓度来指示。因此,本研究旨在了解健康中年人Hb浓度与MDA水平的相关性。方法:2018年1月至2018年3月在沙阿南一所私立大学进行相关研究。在征得同意后,选择16名参与者,年龄在45 - 65岁之间,无已知疾病。采用Pearson相关法对数据进行统计分析。结果:Hb浓度与MDA水平有较强的相关性(r: 0.756, p <0.001)。这意味着当Hb浓度增加时,MDA的产生显著增加。结论:明显健康的中年成人血清丙二醛水平与Hb浓度密切相关。可以推测,正常中年人细胞内呼吸时丙二醛的产生与氧的可利用性有关
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引用次数: 0
Determination of Quality of life, Self-esteem and Self-image in patients with Idiopathic Scoliosis subjected to Surgical treatment in Malaysia 马来西亚手术治疗的特发性脊柱侧凸患者的生活质量、自尊和自我形象的测定
Pub Date : 2019-06-15 DOI: 10.57002/jms.v17i1.256
Marini Ab. Rahman, P. Galaichelvi., N. Nurain
Idiopathic scoliosis is a spinal deformity which affects patient’s self-esteem, self-image and quality of life. Surgery is offered when the curve is more than 45 degree based on its progression. The objective of this study is to determine the pre and post-surgical self-esteem, self-image and quality of life in idiopathic scoliosis patients. A cross sectional study was conducted by using Scoliosis Research Society-30 (SRS-30) self-administered patient questionnaire. There are 115 patients were recruited in this study where 35 (30.43%) male and 80 (69.6%) female patients. Age of patient ranged from 10 to 49 years old with mean age of 24.65 ± 7.704. There were 42 (36.52%) Malay patients, 40 (34.78%) Chinese patients, 25 (21.73%) Indian patients and 8 (6.96%) from other races. Results shows that self-esteem and self-image is significantly higher (r = 0.216, p=0.021) after surgery compared to before surgery. As for quality of life, physical function did not significantly change after surgery but quality of life based on psychological function and social wellbeing is significantly higher after surgery. Positive association were found between satisfaction of treatment with self-image (r = 0.713, p=0.00) and self-image with self-esteem (r = 0.216, p=0.021) and negative association found between satisfaction of treatment with self-esteem (r = - 0.210, p=0.024). In conclusion patients with idiopathic scoliosis report lower self-esteem and self-image before surgical treatment and significantly improves after surgical correction and patients are generally satisfied with their life as well as the outcome of surgical treatment.
特发性脊柱侧凸是一种影响患者自尊、自我形象和生活质量的脊柱畸形。根据病情进展,当曲度超过45度时,可进行手术。本研究的目的是确定特发性脊柱侧凸患者手术前后的自尊、自我形象和生活质量。采用脊柱侧凸研究协会-30 (SRS-30)患者自填问卷进行横断面研究。共纳入115例患者,其中男性35例(30.43%),女性80例(69.6%)。患者年龄10 ~ 49岁,平均年龄24.65±7.704岁。马来人42例(36.52%),华人40例(34.78%),印度人25例(21.73%),其他种族8例(6.96%)。结果显示,术后患者自尊和自我形象明显高于术前(r = 0.216, p=0.021)。在生活质量方面,手术后身体功能无明显变化,但基于心理功能和社会幸福感的生活质量明显高于手术后。自我形象治疗满意度与自尊治疗满意度呈显著正相关(r = 0.713, p=0.00),自尊治疗满意度呈显著负相关(r = - 0.210, p=0.024)。综上所述,特发性脊柱侧凸患者手术前自尊和自我形象较低,手术矫正后自尊和自我形象明显改善,患者对生活和手术治疗效果普遍满意。
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Journal of Management &amp; Science
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