It is unknown that the novel Coronavirus (COVID 19), which emerged for the first time in December 2019 and spread all over the world, have affected how many children symptomatically or asymptomatically. The uncertainty of the treatment algorithm of pandemic factor and rapidly developing pandemic process created a chaotic environment in whole world. Children and adolescents have been adversely affected by this chaotic environment. Studies examining the effects of this period on the mental health of children and adolescents are scarce. It has been suggested that individuals with psychiatric disorders such as attention deficit-hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) adapted more difficultly and were affected more negatively than other individuals. In this study, we present a patient with ADHD and oppositional defiant disorder (ODD) who was using short-acting methylphenidate (IRIS-MPH) for treatment, had no worsening or any adverse side effects and was treated carefully for COVID 19 infection. However, further studies are required to evaluate the safety of IRIS-MPH and other psychotropic agents in patients with COVID 19.
{"title":"Treatment of Attention Deficit - Hyperactivity Disorder in a Pediatric Patient with COVID-19","authors":"Asiye Arıcı Gürbüz, H. Altun","doi":"10.17517/ksutfd.1100749","DOIUrl":"https://doi.org/10.17517/ksutfd.1100749","url":null,"abstract":"It is unknown that the novel Coronavirus (COVID 19), which emerged for the first time in December 2019 and spread all over the world, have affected how many children symptomatically or asymptomatically. The uncertainty of the treatment algorithm of pandemic factor and rapidly developing pandemic process created a chaotic environment in whole world. Children and adolescents have been adversely affected by this chaotic environment. Studies examining the effects of this period on the mental health of children and adolescents are scarce. It has been suggested that individuals with psychiatric disorders such as attention deficit-hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) adapted more difficultly and were affected more negatively than other individuals. In this study, we present a patient with ADHD and oppositional defiant disorder (ODD) who was using short-acting methylphenidate (IRIS-MPH) for treatment, had no worsening or any adverse side effects and was treated carefully for COVID 19 infection. However, further studies are required to evaluate the safety of IRIS-MPH and other psychotropic agents in patients with COVID 19.","PeriodicalId":34113,"journal":{"name":"Kahramanmaras Sutcu Imam Universitesi Tip Fakultesi dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67444037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IN PATIENTS WITH MULTIPLE SCLEROSIS USING OCRELIZUMAB SEROLOGICAL STATUS OF HEPATITIS B VIRUS Abstract Objective B-cell depleting treatments are associated with potential risks of viral infections. Hepatitis B virus (HBV) infection is the most common chronic viral infection and it is estimated that 30% of the world population has serological evidence of current or past infection Material end methods Our study is a single-center, retrospective, cross-sectional study. We retrospectively reviewed the clinical records of MS patients receiving ocrelizumab. Demographic and clinical characteristics of patients, Expanded Disability Status Scale (EDSS), drug history before ocrelizumab for MS; Mean ocrelizumab intake times, smoking status, hepatitis C virus, HIV serological status, HBV serological status, HBV treatment status were recorded. Results The study included 64 MS patients treated with ocrelizumab. The mean age was 41.6±9.8 years (min-max: 21-62 years). 75% of the cases were female (n:48), 25% were male (n:16). HIV and hepatitis C virus serological tests were negative in all cases. HBsAg was found to be positive in 1.6% (n:1) and Anti-HBcIgG in 12.5% (n:8). The number of patients who were started on hepatitis B treatment was 12.5% (n:8), and tenofovir disoproxil was started in 2 patients (25%), entecavir in 5 patients (62.5%), and tenofovir alafenamide in 1 patient (12.5). The mean duration of taking ocrelizumab for the patients was 28.5±13.1 months (min-max: 6-46 months). Conclusion In conclusion, all patients should be screened for HBV before starting ocrelizumab therapy. Both HBsAg and Anti-HBcIg G tests should be used. The isolated presence of Anti-HBcIg G may cause HBV reactivation. Therefore, Anti-HBcIg G should be screened before immunosuppressive therapy.
{"title":"OCRELİZUMAB KULLANAN MULTİPL SKLEROZ HASTALARINDA HEPATİT B VİRÜSÜ SEROLOJİK DURUMU","authors":"Yılmaz İnanç, Selçuk Nazi̇k","doi":"10.17517/ksutfd.1158614","DOIUrl":"https://doi.org/10.17517/ksutfd.1158614","url":null,"abstract":"IN PATIENTS WITH MULTIPLE SCLEROSIS USING OCRELIZUMAB \u0000SEROLOGICAL STATUS OF HEPATITIS B VIRUS \u0000 \u0000Abstract \u0000Objective \u0000B-cell depleting treatments are associated with potential risks of viral infections. Hepatitis B virus (HBV) infection is the most common chronic viral infection and it is estimated that 30% of the world population has serological evidence of current or past infection \u0000Material end methods \u0000Our study is a single-center, retrospective, cross-sectional study. We retrospectively reviewed the clinical records of MS patients receiving ocrelizumab. Demographic and clinical characteristics of patients, Expanded Disability Status Scale (EDSS), drug history before ocrelizumab for MS; Mean ocrelizumab intake times, smoking status, hepatitis C virus, HIV serological status, HBV serological status, HBV treatment status were recorded. \u0000Results \u0000The study included 64 MS patients treated with ocrelizumab. The mean age was 41.6±9.8 years (min-max: 21-62 years). 75% of the cases were female (n:48), 25% were male (n:16). \u0000HIV and hepatitis C virus serological tests were negative in all cases. HBsAg was found to be positive in 1.6% (n:1) and Anti-HBcIgG in 12.5% (n:8). The number of patients who were started on hepatitis B treatment was 12.5% (n:8), and tenofovir disoproxil was started in 2 patients (25%), entecavir in 5 patients (62.5%), and tenofovir alafenamide in 1 patient (12.5). The mean duration of taking ocrelizumab for the patients was 28.5±13.1 months (min-max: 6-46 months). \u0000Conclusion \u0000In conclusion, all patients should be screened for HBV before starting ocrelizumab therapy. Both HBsAg and Anti-HBcIg G tests should be used. The isolated presence of Anti-HBcIg G may cause HBV reactivation. Therefore, Anti-HBcIg G should be screened before immunosuppressive therapy.","PeriodicalId":34113,"journal":{"name":"Kahramanmaras Sutcu Imam Universitesi Tip Fakultesi dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47135634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Obesity is one of the predominant risk factors associated with insulin resistance (IR), type 2 diabetes, and many metabolic syndromes. In this study, we aimed to investigate inflammatory parameters and their relationship with IR and blood groups in obese individuals. Materials and Methods: The demographic characteristics, body mass index (BMI), biochemical parameters, hemogram values, and blood group types of individuals in the obesity and control groups were recorded and compared. Results: The mean age was 37.37±11.43 years in obese individuals and 41.8% (n=77) of them had IR. Neutrophil and monocyte counts of the obese individuals with IR were significantly higher than those of the individuals without IR in the control and the obesity groups (p
{"title":"Obezitede İnsülin Direnci ve İnflamasyon","authors":"Orkun Sariçam","doi":"10.17517/ksutfd.1114938","DOIUrl":"https://doi.org/10.17517/ksutfd.1114938","url":null,"abstract":"Objectives: Obesity is one of the predominant risk factors associated with insulin resistance (IR), type 2 diabetes, and many metabolic syndromes. In this study, we aimed to investigate inflammatory parameters and their relationship with IR and blood groups in obese individuals. \u0000Materials and Methods: The demographic characteristics, body mass index (BMI), biochemical parameters, hemogram values, and blood group types of individuals in the obesity and control groups were recorded and compared. \u0000Results: The mean age was 37.37±11.43 years in obese individuals and 41.8% (n=77) of them had IR. Neutrophil and monocyte counts of the obese individuals with IR were significantly higher than those of the individuals without IR in the control and the obesity groups (p","PeriodicalId":34113,"journal":{"name":"Kahramanmaras Sutcu Imam Universitesi Tip Fakultesi dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67443835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Özge KAMA BAŞCI, Ferhat Ekinci, Atike Pınar Erdoğan, E. Eser
Objectives: This study aimed to reveal the prevalence of burnout syndrome among physicians, nurses and biologists working in oncology clinics in Turkey. Sociodemographic factors affecting burnout were revealed . The adequacy of institutional measures was questioned and their participation in solution proposals was examined. Material and Methods: This cross-sectionally designed study aimed to reach all actively working medical oncology staff in Turkey. 323 of them agreed to participate in the study. Maslach Burnout Inventory (MBI) was used to measure the burnout status of the participants. Clinical burnout reduction solutions were also questioned. The burnout prevention questions were prepared. Statistical significance was considered, and all statistical tests were two-sided (p < 0.05). Results: Of 323 participants, 38% were medical oncologists, 58% were nurses and 4% were biologists. The median age was 37±9. According to the MBI subscales, the mean±SD burnout levels of the oncology staff are 19.7±7.8 (high) for EE, 6±4.3 (moderate) for DP and 20.9±5.1 (high) for PA. Respondents under 41 age has higher risk. The participants who are having a hobby, good sleep pattern, making regular exercises has significantly lower burnout scores. Conclusion: Burnout syndrome was detected in more than half of oncology workers. Personal factors such as young age, family type, sleep, exercise and having a hobby affect burnout. preventive measures and interventions are required for health workers
{"title":"Tıbbi Onkoloji Çalışanlarında Tükenmişlik: Ulusal Gerçeklerle Yüzleşmek","authors":"Özge KAMA BAŞCI, Ferhat Ekinci, Atike Pınar Erdoğan, E. Eser","doi":"10.17517/ksutfd.1151313","DOIUrl":"https://doi.org/10.17517/ksutfd.1151313","url":null,"abstract":"Objectives: This study aimed to reveal the prevalence of burnout syndrome among physicians, nurses and biologists working in oncology clinics in Turkey. Sociodemographic factors affecting burnout were revealed . The adequacy of institutional measures was questioned and their participation in solution proposals was examined. \u0000Material and Methods: This cross-sectionally designed study aimed to reach all actively working medical oncology staff in Turkey. 323 of them agreed to participate in the study. Maslach Burnout Inventory (MBI) was used to measure the burnout status of the participants. Clinical burnout reduction solutions were also questioned. The burnout prevention questions were prepared. Statistical significance was considered, and all statistical tests were two-sided (p < 0.05). \u0000Results: Of 323 participants, 38% were medical oncologists, 58% were nurses and 4% were biologists. The median age was 37±9. According to the MBI subscales, the mean±SD burnout levels of the oncology staff are 19.7±7.8 (high) for EE, 6±4.3 (moderate) for DP and 20.9±5.1 (high) for PA. Respondents under 41 age has higher risk. The participants who are having a hobby, good sleep pattern, making regular exercises has significantly lower burnout scores. \u0000Conclusion: Burnout syndrome was detected in more than half of oncology workers. Personal factors such as young age, family type, sleep, exercise and having a hobby affect burnout. preventive measures and interventions are required for health workers","PeriodicalId":34113,"journal":{"name":"Kahramanmaras Sutcu Imam Universitesi Tip Fakultesi dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67444133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The aim of this study was to explore the experiences of undergraduate nursing students of the implementation of case-based learning technique with group work in in clinical setting at the Surgical Diseases Nursing. Material and methods: A qualitative design was used. The sample consisted of sophomore students (n=84) who took Surgical Diseases Nursing at a University School of Health in the Spring Semester of 2018-2019. The students were divided into 14 groups by random sampling method according class list. The practice instructors advised the gropus in the process of Case-Based Learning technique for 8 weeks and groups took real case (patient) in clinical setting and gave nursing care. Groups used Surgical Diseases Nursing Patient Assesment form. The students planned their nursing care plans using NANDA nursing diagnoses with group work and then evaluated the result by applying the care plan. In the last two weeks of the academic year, the students were able to present their presentations. Results: The experiences of the students are explained in three main themes and 9 sub-themes. Main themes were; case presentation experience, case presentation in nursing practice, a good case presentation. Conclusion: As a result, Case-Based Learning facilitates learning, provides materialization and permanence of knowledge, offers the opportunity to combine the application with the theory and preparing students for the profession.
{"title":"Learning Experiences of Nursing Students With Case-Based Learning Technique: A Qualitative Study","authors":"Yasemin Altinbaş, Emine Derya Ister","doi":"10.17517/ksutfd.1123476","DOIUrl":"https://doi.org/10.17517/ksutfd.1123476","url":null,"abstract":"Objective: The aim of this study was to explore the experiences of undergraduate nursing students of the implementation of case-based learning technique with group work in in clinical setting at the Surgical Diseases Nursing. \u0000Material and methods: A qualitative design was used. The sample consisted of sophomore students (n=84) who took Surgical Diseases Nursing at a University School of Health in the Spring Semester of 2018-2019. The students were divided into 14 groups by random sampling method according class list. The practice instructors advised the gropus in the process of Case-Based Learning technique for 8 weeks and groups took real case (patient) in clinical setting and gave nursing care. Groups used Surgical Diseases Nursing Patient Assesment form. The students planned their nursing care plans using NANDA nursing diagnoses with group work and then evaluated the result by applying the care plan. In the last two weeks of the academic year, the students were able to present their presentations. \u0000Results: The experiences of the students are explained in three main themes and 9 sub-themes. Main themes were; case presentation experience, case presentation in nursing practice, a good case presentation. \u0000Conclusion: As a result, Case-Based Learning facilitates learning, provides materialization and permanence of knowledge, offers the opportunity to combine the application with the theory and preparing students for the profession.","PeriodicalId":34113,"journal":{"name":"Kahramanmaras Sutcu Imam Universitesi Tip Fakultesi dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67443880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gamze Ertaş, Hamiyet ŞENOL ÇAKMAK, Sevinç Akdeni̇z, E. Polat, Ilker Hasan Karal, Serkan Tulgar
Amaç: Minimal invaziv endovasküler stent greftleme yöntemleri olan endovasküler aort onarımı (EVAR) ve torasik endovasküler aort onarımı (TEVAR), aort anevrizmalarının tedavisinde geleneksel ve invaziv açık cerrahiye alternatif olarak uygulanmaktadır. Bu çalışmanın amacı hastanemizde EVAR ve TEVAR uygulanan hastalarda uygulanan anestezi yöntemlerini değerlendirmektir. Yöntemler: 01.01.2015-31.05.2022 tarihleri arasında endovasküler aort onarımı yapılan 95 hastanın dosyaları geriye dönük olarak incelendi. Hastalara ilişkin tanımlayıcı verilerin yanı sıra ameliyat süresi, yoğun bakım ve hastanede kalış süresi gibi veriler toplanarak değerlendirildi. Bulgular: Endovasküler aortik greftlemenin 14 hastaya genel anestezi (GA) (Grup GA) altında, 67 hastaya sedo-analjezi (SA) (Grup SA) altında yapıldığı belirlendi. 75 hastaya EVAR, 6 hastaya TEVAR uygulandı. EVAR hastalarının 11'inin GA, 64'ünün SA ile tedavi edildiği görüldü. Hastaların yaş ortalaması 68.73±8.31 yıl olup, 75'i erkekti. Hasta komorbiditeleri göz önüne alındığında gruplar arasında anlamlı fark yoktu (p>0.05). Yoğun bakımda kalış süreleri hastanede kalış süreleri açısından değerlendirildiğinde gruplar arasında istatistiksel olarak anlamlı fark bulunmadı (p>0.05). Sonuç: Bu çalışmada kliniğimizde EVAR/TEVAR uygulanan hastalarda intraoperatif sıvı gereksinimi dışında anestezi yönteminin üstünlüğünü belirleyemedik.
目标是将血管内主动脉修复（EVAR）和toracic血管内主动脉修补（TEVAR）与微创血管内支架移植方法应用于传统和有创开放手术。Buçalışmanın amacıhastanemizde EVAR ve TEVAR维吾尔族hastalarda维吾尔族anestezi yöntemlerini değerlendirmektir。方法：在2015年1月1日至2022年5月31日期间，对95名患者的血管内主动脉修复进行了回顾。通过收集数据对患者进行评估，包括手术持续时间、重症监护和住院生存时间。研究结果发现，67名患者在14次全身麻醉（GA）（GA组）下进行了血管内主动脉移植物的sedo分析（SA）（SA组）。EVAR已用于6名患者中的75名患者。11例EVAR患者接受GA治疗，64例接受SA治疗。患者平均年龄为68.73±8.31，男性75例。当患者暴露在燃烧中时，各组之间没有显著差异（p>0.05）。相反，各组之间对住院的剩余时间进行了统计评估（p>0.05），因此，在本研究中，EVAR/TEVAR患者需要术中液体。我们没有确定这条路的优势。
{"title":"Endovasküler Aort Anevrizması Onarımın Cerrahilerine Anestezist Bakışı; Tek Merkezli Retrospektif Bir Çalışma","authors":"Gamze Ertaş, Hamiyet ŞENOL ÇAKMAK, Sevinç Akdeni̇z, E. Polat, Ilker Hasan Karal, Serkan Tulgar","doi":"10.17517/ksutfd.1162380","DOIUrl":"https://doi.org/10.17517/ksutfd.1162380","url":null,"abstract":"Amaç: Minimal invaziv endovasküler stent greftleme yöntemleri olan endovasküler aort onarımı (EVAR) ve torasik endovasküler aort onarımı (TEVAR), aort anevrizmalarının tedavisinde geleneksel ve invaziv açık cerrahiye alternatif olarak uygulanmaktadır. Bu çalışmanın amacı hastanemizde EVAR ve TEVAR uygulanan hastalarda uygulanan anestezi yöntemlerini değerlendirmektir. \u0000Yöntemler: 01.01.2015-31.05.2022 tarihleri arasında endovasküler aort onarımı yapılan 95 hastanın dosyaları geriye dönük olarak incelendi. Hastalara ilişkin tanımlayıcı verilerin yanı sıra ameliyat süresi, yoğun bakım ve hastanede kalış süresi gibi veriler toplanarak değerlendirildi. \u0000Bulgular: Endovasküler aortik greftlemenin 14 hastaya genel anestezi (GA) (Grup GA) altında, 67 hastaya sedo-analjezi (SA) (Grup SA) altında yapıldığı belirlendi. 75 hastaya EVAR, 6 hastaya TEVAR uygulandı. EVAR hastalarının 11'inin GA, 64'ünün SA ile tedavi edildiği görüldü. Hastaların yaş ortalaması 68.73±8.31 yıl olup, 75'i erkekti. Hasta komorbiditeleri göz önüne alındığında gruplar arasında anlamlı fark yoktu (p>0.05). Yoğun bakımda kalış süreleri hastanede kalış süreleri açısından değerlendirildiğinde gruplar arasında istatistiksel olarak anlamlı fark bulunmadı (p>0.05). \u0000 Sonuç: Bu çalışmada kliniğimizde EVAR/TEVAR uygulanan hastalarda intraoperatif sıvı gereksinimi dışında anestezi yönteminin üstünlüğünü belirleyemedik.","PeriodicalId":34113,"journal":{"name":"Kahramanmaras Sutcu Imam Universitesi Tip Fakultesi dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49049828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Biological variation-(BV) data of analytes have been used to evaluate the significant changes in serial results of healthy individuals in clinical laboratories. The aim of this study was to calculate within-(CVw)-(within-individual BV) and between-individual (CVg)-BV, index of individuality,and RCV of urine Melatonin analyte in patients with Chronic Hepatitis B(CHB). Material and Methods: 20-CHB patients and 20 healthy individuals as control were involved in this study. Index of individuality and reference change value were calculated from within-subject and between-subject variations. Melatonin levels in human urines was measured with commercial a kit by-ELISA.ANOVA test was used to calculate the variations. Results: Melatonin were significantly higher in patients with CHB compared to healthy subjects. Also,RCV of Melatonin analyte in CHB patients was relatively higher, because of high within-subject variation,resulting in a higher RCV. Conclusion: RCV concept for predicting the clinical status in CHB patients represents an optimization of laboratory reporting and could be a valuable tool for clinical decision.
{"title":"BIOLOGICAL VARIATIONS OF URINARY MELATONIN LEVELS IN PATIENTS WITH CHRONIC HEPATITIS B","authors":"Erkan Öner, Ergul Belge Kurutas","doi":"10.17517/ksutfd.1102203","DOIUrl":"https://doi.org/10.17517/ksutfd.1102203","url":null,"abstract":"Objective: Biological variation-(BV) data of analytes have been used to evaluate the significant changes in serial results of healthy individuals in clinical laboratories. The aim of this study was to calculate within-(CVw)-(within-individual BV) and between-individual (CVg)-BV, index of individuality,and RCV of urine Melatonin analyte in patients with Chronic Hepatitis B(CHB). \u0000Material and Methods: 20-CHB patients and 20 healthy individuals as control were involved in this study. Index of individuality and reference change value were calculated from within-subject and between-subject variations. Melatonin levels in human urines was measured with commercial a kit by-ELISA.ANOVA test was used to calculate the variations. \u0000Results: Melatonin were significantly higher in patients with CHB compared to healthy subjects. Also,RCV of Melatonin analyte in CHB patients was relatively higher, because of high within-subject variation,resulting in a higher RCV. \u0000Conclusion: RCV concept for predicting the clinical status in CHB patients represents an optimization of laboratory reporting and could be a valuable tool for clinical decision.","PeriodicalId":34113,"journal":{"name":"Kahramanmaras Sutcu Imam Universitesi Tip Fakultesi dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67444111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giriş: Dünya Sağlık Örgütü (DSÖ) tarafından Aralık 2019 yılında pandemi ilan edilen COVİD-19 salgını sonrası, Mart’ın ikinci haftasından itibaren ülkemizde olgular bildirilmiştir. COVİD-19 olgularının %5’inde hastalığın seyri sırasında yoğun bakım ünitesine (YBÜ) yatış ihtiyacı gelişmektedir.Bu çalışma ile YBÜ’de izlediğimiz kritik durumdaki COVİD-19 hastalarından sürekli renal replasman(CRRT) tedavisi ihtiyacı olan hastaların mortalite oranlarını APACHE-II ve SOFA skoru ile değerlendirmesi amaçlanmıştır. Gereç ve Yöntem: Mart –Eylül 2020 arasında Eğitim Araştırma Hastanesinin Anestezi Yoğun Bakım Ünitesine yatırılıp CRRT ihtiyacı olan 13 hasta APACHE-II ve SOFA skorlama sistemi ile değerlendirildi.CRRT uygulamasından önce ve uygulamadan 2 gün sonra APACHE-II ve SOFA skorları kayıt edildi. Mortalite açısından skorlama sistemileri kıyaslandı. Bulgular: CRRT öncesi ve sonrası APACHE-II ve SOFA skorlama sitemleriine bakıldığında; CRRT öncesi APACHE-II skorlama sisteminin tahmini ölüm oranın öngörmede daha belirleyici olduğu; fakat CRRT sonrası APACHE-II ve SOFA skorlama sisteminin birbiriyle farkı olmadığı görülmüştür.Hastanede yatış süreleri değerlendirildiğinde;APACHE-II ile SOFA skorlama sistemi arasında negatif yönde bir ilişki bulunmuştur. Sonuç: Çalışmamız literatür ile uyumlu olarak erkeklerde ve hipertansiyonu olan hastalarda mortalitenin daha yüksek olduğunu göstermiştir. APACHE-II ve SOFA skoru arasında CRRT sonrasında mortalite açısından fark olmadığını her iki sisteminde kullanılabileceğini göstermektedir. Bu sonuçların gelecekteki takip ve tedavi yöntemlerine katkı sağlayabileceği düşünülmekle birlikte yeni çalışmalara ihtiyaç vardır.
入口：杜冲776nya凹陷冲774；奥冲776rgu冲776tu；2019冠状病毒病改善了在疾病过程中投资于高风险监测单位（EMU）的需求。本研究旨在通过APACHE-II和SOFA评分评估我们在YBI观察到的病情危重的新冠肺炎患者中持续需要肾复制瘤（CRRT）的患者的死亡率。要求和方法：在2020年3月至9月期间，研究医院接受了APACHE-II和SOFA评分系统的评估，该系统需要CRRT。CRRT应用前后两天，记录APACHE-II和SOFA评分。评分系统与死亡率进行比较。研究结果是：当你查看CRRT前后的APACHE-II和SOFA评分网站时；CRRTöncesi APACHE-II系统在塔赫米尼ölüm oranınöngörmede daha belerleici olduğu；fakat CRRT sonrasıAPACHE-II ve SOFA skorrama系统在birbiriyle farkıolmadığıgörülmüştür。当对医院进行评估时，APACHE-II与SOFA评分系统呈负相关。因此，我们的研究表明，根据文献，男性和高血压患者的死亡率更高。APACHE-II和SOFA评分显示，CRRT后，它可以在两个系统中使用，与死亡率没有什么不同。需要考虑这些结果，以便为未来的监测和治疗方法做出贡献。
{"title":"EVALUATION OF PATIENTS DIAGNOSED WITH COVID-19 AND FOLLOWED UP IN INTENSIVE CARE UNIT REQUIRING CONTINUOUS RENAL REPLACEMENT THERAPY USING APACHE-II AND SOFA SCORES","authors":"İrem Akın Şen, Ş. Arslan, Cem Şen","doi":"10.17517/ksutfd.1164300","DOIUrl":"https://doi.org/10.17517/ksutfd.1164300","url":null,"abstract":"Giriş: Dünya Sağlık Örgütü (DSÖ) tarafından Aralık 2019 yılında pandemi ilan edilen COVİD-19 salgını sonrası, Mart’ın ikinci haftasından itibaren ülkemizde olgular bildirilmiştir. COVİD-19 olgularının %5’inde hastalığın seyri sırasında yoğun bakım ünitesine (YBÜ) yatış ihtiyacı gelişmektedir.Bu çalışma ile YBÜ’de izlediğimiz kritik durumdaki COVİD-19 hastalarından sürekli renal replasman(CRRT) tedavisi ihtiyacı olan hastaların mortalite oranlarını APACHE-II ve SOFA skoru ile değerlendirmesi amaçlanmıştır. \u0000Gereç ve Yöntem: Mart –Eylül 2020 arasında Eğitim Araştırma Hastanesinin Anestezi Yoğun Bakım Ünitesine yatırılıp CRRT ihtiyacı olan 13 hasta APACHE-II ve SOFA skorlama sistemi ile değerlendirildi.CRRT uygulamasından önce ve uygulamadan 2 gün sonra APACHE-II ve SOFA skorları kayıt edildi. Mortalite açısından skorlama sistemileri kıyaslandı. \u0000Bulgular: CRRT öncesi ve sonrası APACHE-II ve SOFA skorlama sitemleriine bakıldığında; CRRT öncesi APACHE-II skorlama sisteminin tahmini ölüm oranın öngörmede daha belirleyici olduğu; fakat CRRT sonrası APACHE-II ve SOFA skorlama sisteminin birbiriyle farkı olmadığı görülmüştür.Hastanede yatış süreleri değerlendirildiğinde;APACHE-II ile SOFA skorlama sistemi arasında negatif yönde bir ilişki bulunmuştur. \u0000Sonuç: Çalışmamız literatür ile uyumlu olarak erkeklerde ve hipertansiyonu olan hastalarda mortalitenin daha yüksek olduğunu göstermiştir. APACHE-II ve SOFA skoru arasında CRRT sonrasında mortalite açısından fark olmadığını her iki sisteminde kullanılabileceğini göstermektedir. Bu sonuçların gelecekteki takip ve tedavi yöntemlerine katkı sağlayabileceği düşünülmekle birlikte yeni çalışmalara ihtiyaç vardır.","PeriodicalId":34113,"journal":{"name":"Kahramanmaras Sutcu Imam Universitesi Tip Fakultesi dergisi","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67444524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The aim of this study was to examine the Neutrophil/Lymphocyte Ratio(NLR), Platelet/Lymphocyte Ratios(PLR), and Mean Platelet Volume(MPV), red blood cell distribution width(RDW) and leukocyte cell levels of patients with Axis-I psychiatric disease by comparing them with each other and healthy controls. Material and Methods: A total of 600 people were included in our study, 500 of whom were taken as the patient and 100 as the control group. The diagnosis of patients according to DSM-5-Criteria were 34.8% Schizophrenia, 21% had Generalized-Anxiety-Disorder, 14.4% had Bipolar-Affective-Disorder, 14% had Major-Depressive-Disorder, 7.2% had Adjustment-Disorder, 4.2% had Schizoaffective-Disorder, 3.6% had other psychiatric illnesses. Results: It was seen that hemoglobin, platelet, monocyte, blood platelet distribution (PCT), percentage account of RDW (RDW-CV) did not have statistically significant differences between groups (p values were 0.082, 0.214, 0.526, 0.082, 0.771, respectively). The lymphocyte, eosinophil, basophil, MPV, standard deviation of RDW (RDW-SD) were higher compared with healthy controls (p values were 0.002, 0.003,
{"title":"Kronik psikiyatri hastalarında inflamasyon: nötrofil/lenfosit, platelet/lenfosit oranları ve ortalama trombosit hacmi","authors":"Figen UNAL DEMİR, Filiz Özsoy, Esma AKPINAR ASLAN","doi":"10.17517/ksutfd.1127281","DOIUrl":"https://doi.org/10.17517/ksutfd.1127281","url":null,"abstract":"Objective: The aim of this study was to examine the Neutrophil/Lymphocyte Ratio(NLR), Platelet/Lymphocyte Ratios(PLR), and Mean Platelet Volume(MPV), red blood cell distribution width(RDW) and leukocyte cell levels of patients with Axis-I psychiatric disease by comparing them with each other and healthy controls. \u0000Material and Methods: A total of 600 people were included in our study, 500 of whom were taken as the patient and 100 as the control group. The diagnosis of patients according to DSM-5-Criteria were 34.8% Schizophrenia, 21% had Generalized-Anxiety-Disorder, 14.4% had Bipolar-Affective-Disorder, 14% had Major-Depressive-Disorder, 7.2% had Adjustment-Disorder, 4.2% had Schizoaffective-Disorder, 3.6% had other psychiatric illnesses. \u0000Results: It was seen that hemoglobin, platelet, monocyte, blood platelet distribution (PCT), percentage account of RDW (RDW-CV) did not have statistically significant differences between groups (p values were 0.082, 0.214, 0.526, 0.082, 0.771, respectively). The lymphocyte, eosinophil, basophil, MPV, standard deviation of RDW (RDW-SD) were higher compared with healthy controls (p values were 0.002, 0.003,","PeriodicalId":34113,"journal":{"name":"Kahramanmaras Sutcu Imam Universitesi Tip Fakultesi dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67443896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amaç: Akut apandisit, çocuk cerrahisi pratiğinde en önemli ve yaygın olarak uygulanan acil cerrahilerden biridir. Çocuklarda apandisit tanısı yetişkinlere göre daha zordur. Olgunlaşmamış granülosit yüzdesi (%IG) son zamanlarda erişkin popülasyonda inflamasyon şiddetinin saptanması için laboratuvar parametresi olarak araştırılmaktadır. Çalışmanın amacı, pediatrik akut apandisit erken tanısında IG sayısı ve yüzde rolünün belirlenmesidir. Gereç ve Yöntemler: Ocak 2021-Aralık 2022 tarihleri arasında karın ağrısı şikayeti ile Acil Servise başvuran ve preoperatif akut apandisit tanısı ile opere edilen hastaların verileri hastane kayıtlarından geriye dönük olarak incelendi. 18 yaş altı, akut apandisit ön tanısı ile ameliyat edilen ve hemogramı olan hastalar çalışmaya dahil edildi. Bulgular: Çalışmaya 108 hasta dahil edildi. Akut apandisit grubunda 48 hasta, perfore apandisit grubunda 9 hasta ve kontrol grubunda 53 hasta vardı. Apandisit ve kontrol grubundaki hastalarda ortalama IG %'si sırasıyla 0,31±0,37 ve 0,96±5,1 idi. Apandisit hastaları ile kontrol grubu arasında IG sayısı ve yüzdesi açısından anlamlı fark bulunmadı. Akut ve perfore apandisit arasında IG sayısı ve IG % açısından istatistiksel olarak anlamlı fark bulunmadı. Sonuç: IG sayısı ve IG%, herhangi bir ek fayda sağlamadı ve klinisyen için akut apandisit belirlemede kesin bir biyobelirteç değil. Akut apandisit tanısı için anamnez, fizik muayene ve laboratuvar testinin bir kombinasyonu altın standart olmaya devam etmektedir.
目的是：急性胰腺炎是儿童外科最重要、最常用的急诊外科医生之一。儿童的冷漠比成年人更难识别。最近，研究将未成熟颗粒率（%IG）作为实验室参数，以测试可用人群中的炎症暴力。这项工作的目的是尽早确定IG的数量和作用。要求和方法：2021-2022年1月，针对急诊和术前急性操作手报告的女性疼痛投诉，对根据急诊报告进行手术的患者的数据进行了审查。本研究纳入了16岁的患者，这些患者预先诊断为急性冷漠，并进行了血液描记术。事件：108名患者被纳入研究。急性停搏组48例，穿支停搏组9例，对照组53例。贫血患者和对照组的平均IG%分别为0.31±0.37和0.96±5.1。Apandisit hastalarıile kontrol grubu arasında IG sayısıve yüzdesi açısşndan anlamlıfark bulunmadı。ACT和穿孔剂之间的IG数量和IG%在统计学上没有差异。因此，IG和IG%的数量根本没有受益，临床医生对急性冷漠的判断也不是绝对的生物生物学家。对于急性胰腺炎的定义，贫血、体检和实验室检查仍然是金标准的结合。
{"title":"Apandisit ayırıcı tanısında immatür granülosit sayısının ve yüzdesinin rolü","authors":"İlknur BANLI CESUR, Zerrin Özçelik, Selçuk Matyar, Günay Ekberli̇","doi":"10.17517/ksutfd.1135753","DOIUrl":"https://doi.org/10.17517/ksutfd.1135753","url":null,"abstract":"Amaç: Akut apandisit, çocuk cerrahisi pratiğinde en önemli ve yaygın olarak uygulanan acil cerrahilerden biridir. Çocuklarda apandisit tanısı yetişkinlere göre daha zordur. Olgunlaşmamış granülosit yüzdesi (%IG) son zamanlarda erişkin popülasyonda inflamasyon şiddetinin saptanması için laboratuvar parametresi olarak araştırılmaktadır. Çalışmanın amacı, pediatrik akut apandisit erken tanısında IG sayısı ve yüzde rolünün belirlenmesidir. \u0000Gereç ve Yöntemler: Ocak 2021-Aralık 2022 tarihleri arasında karın ağrısı şikayeti ile Acil Servise başvuran ve preoperatif akut apandisit tanısı ile opere edilen hastaların verileri hastane kayıtlarından geriye dönük olarak incelendi. 18 yaş altı, akut apandisit ön tanısı ile ameliyat edilen ve hemogramı olan hastalar çalışmaya dahil edildi. \u0000Bulgular: Çalışmaya 108 hasta dahil edildi. Akut apandisit grubunda 48 hasta, perfore apandisit grubunda 9 hasta ve kontrol grubunda 53 hasta vardı. Apandisit ve kontrol grubundaki hastalarda ortalama IG %'si sırasıyla 0,31±0,37 ve 0,96±5,1 idi. Apandisit hastaları ile kontrol grubu arasında IG sayısı ve yüzdesi açısından anlamlı fark bulunmadı. Akut ve perfore apandisit arasında IG sayısı ve IG % açısından istatistiksel olarak anlamlı fark bulunmadı. \u0000Sonuç: IG sayısı ve IG%, herhangi bir ek fayda sağlamadı ve klinisyen için akut apandisit belirlemede kesin bir biyobelirteç değil. Akut apandisit tanısı için anamnez, fizik muayene ve laboratuvar testinin bir kombinasyonu altın standart olmaya devam etmektedir.","PeriodicalId":34113,"journal":{"name":"Kahramanmaras Sutcu Imam Universitesi Tip Fakultesi dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49002464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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