Lancet Healthy Longevity最新文献

{"title":"Prevalence of dementia among Indigenous populations of countries with a very high Human Development Index: a systematic review.","authors":"Antonia J Clarke, Maja Christensen, Anna H Balabanski, Angela Dos Santos, Peter A Barber, Alex Brown, Matire Harwood, Christina Storm Mienna, Donald K Warne, Marwan Ahmed, Judith M Katzenellenbogen, Adrienne Withall, Kylie Radford, Amy G Brodtmann","doi":"10.1016/j.lanhl.2024.100658","DOIUrl":"10.1016/j.lanhl.2024.100658","url":null,"abstract":"<p><p>Dementia is a health priority for Indigenous peoples. Here, we reviewed studies on the prevalence of dementia or cognitive impairment among Indigenous populations from countries with a very high Human Development Index (≥0·8). Quality was assessed using the Joanna Briggs Institute risk-of-bias tool and CONSolIDated critERia for strengthening the reporting of health research involving Indigenous peoples (CONSIDER), with oversight provided by an Indigenous Advisory Board. After screening, 23 studies were included in the Review. Relative to the respective non-Indigenous populations, greater age-standardised prevalence ratios were observed in the Australian Aboriginal and Torres Strait Islander (2·5-5·2), Aotearoa-New Zealand Māori (1·2-2·0), and Singaporean Malay (1·3-1·7) populations, and greater crude prevalence ratios were observed in the Canadian First Nation (1·3), Singaporean Malay (2·3), Malaysian Melanau (1·7-4·0), American Indian and Alaska Native (1·0-3·2), and Chamorro of Guam (1·2-2·0) populations. The prevalence ratios were greater across younger age groups, predominantly comprising those younger than 70 years. 14 studies presented a moderate risk of bias and few studies reported Indigenous involvement. Despite improved management of risk factors, a greater prevalence of dementia persists in Indigenous populations, overall and at younger ages than in non-Indigenous populations. Future epidemiological work involving Indigenous populations should uphold and prioritise Indigenous perspectives.</p>","PeriodicalId":34394,"journal":{"name":"Lancet Healthy Longevity","volume":" ","pages":"100658"},"PeriodicalIF":13.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Next generation brain health: transforming global research and public health to promote prevention of dementia and reduce its risk in young adult populations.","authors":"Francesca R Farina, Katie Bridgeman, Sarah Gregory, Lucía Crivelli, Isabelle F Foote, Otto-Emil I Jutila, Ludmila Kucikova, Luciano I Mariano, Kim-Huong Nguyen, Tony Thayanandan, Funmi Akindejoye, Joe Butler, Ismael L Calandri, Giedrė Čepukaitytė, Scott T Chiesa, Walter D Dawson, Kay Deckers, Vanessa De la Cruz-Góngora, Maria-Eleni Dounavi, Ishtar Govia, Edmarie Guzmán-Vélez, Shimaa A Heikal, Tanisha G Hill-Jarrett, Agustín Ibáñez, Bryan D James, Eimear McGlinchey, Donncha S Mullin, Graciela Muniz-Terrera, Maritza Pintado Caipa, Esraa M Qansuwa, Louise Robinson, Antonella Santuccione Chadha, Oliver M Shannon, Li Su, Wendy Weidner, Laura Booi","doi":"10.1016/j.lanhl.2024.100665","DOIUrl":"10.1016/j.lanhl.2024.100665","url":null,"abstract":"<p><p>Efforts to prevent dementia can benefit from precision interventions delivered to the right population at the right time; that is, when the potential to reduce risk is the highest. Young adults (aged 18-39 years) are a neglected population in dementia research and policy making despite being highly exposed to several known modifiable risk factors. The risk and protective factors that have the biggest effect on dementia outcomes in young adulthood, and how these associations differ across regions and groups, still remain unclear. To address these uncertainties, the Next Generation Brain Health team convened a multidisciplinary expert group representing 15 nations across six continents. We identified several high-priority modifiable factors in young adulthood and devised five key recommendations for promoting brain health, ranging from individual to policy levels. Increasing research and policy focus on brain health across the life course, inclusive of younger populations, is the next crucial step in the efforts to prevent dementia at the global level.</p>","PeriodicalId":34394,"journal":{"name":"Lancet Healthy Longevity","volume":" ","pages":"100665"},"PeriodicalIF":13.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intervention accelerator to prevent and respond to abuse of older people: insights from key promising interventions.","authors":"Laura Campo-Tena, Aresya Farzana, David Burnes, Titus A Chan, Wan Yuen Choo, Mélanie Couture, Fatemeh Estebsari, Minying He, Jeffrey H Herbst, Christelle Sibdou Liliane Kafando, Joshua Lachs, George Rouamba, Marie-Madeleine Simbreni, Louis To, Hau Yan Wan, Elsie Yan, Yongjie Yon, Christopher Mikton","doi":"10.1016/j.lanhl.2024.100647","DOIUrl":"10.1016/j.lanhl.2024.100647","url":null,"abstract":"<p><p>Globally, abuse of older people (AOP) affects one in six individuals aged 60 years and older every year. Despite the widespread prevalence of AOP, evidence-based interventions for preventing and responding to this issue are insufficient. To address this gap, WHO proposed an initiative to accelerate the development of effective interventions for AOP across all country income levels. In the first phase, the initiative identified 89 promising interventions across a total of 101 evaluations or descriptions, which led to the creation of a public database. Most interventions targeted physical, psychological, and financial abuse and neglect, were implemented in the USA, and focused on victims or potential victims. These interventions were primarily delivered by social workers and nurses, usually in health-care facilities and community centres. Face-to-face delivery was common. Additionally, 28 (28%) of the 101 evaluations used randomised controlled trial designs. The results of this Review can be used to identify interventions that are ready for a rigorous outcome evaluation.</p>","PeriodicalId":34394,"journal":{"name":"Lancet Healthy Longevity","volume":" ","pages":"100647"},"PeriodicalIF":13.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geriatricians-on-the-Move for sustainable ageing.","authors":"Anton De Spiegeleer, Bart De Spiegeleer","doi":"10.1016/j.lanhl.2024.100661","DOIUrl":"10.1016/j.lanhl.2024.100661","url":null,"abstract":"","PeriodicalId":34394,"journal":{"name":"Lancet Healthy Longevity","volume":" ","pages":"100661"},"PeriodicalIF":13.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of age and exposure duration in the association between metabolic syndrome and risk of incident dementia: a prospective cohort study.","authors":"Danial Qureshi, Robert Luben, Shabina Hayat, Robert Talarico, Naomi E Allen, Elżbieta Kuźma, Thomas J Littlejohns","doi":"10.1016/j.lanhl.2024.100652","DOIUrl":"10.1016/j.lanhl.2024.100652","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Metabolic syndrome could be a modifiable risk factor for dementia. However, the effects of age and duration of exposure to metabolic syndrome on dementia risk remains underexplored. The aim of this study was to determine whether the association between metabolic syndrome and risk of dementia differs across mid-life versus late-life, and to explore how duration of metabolic syndrome affects this risk.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We conducted a population-based prospective study using data from the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) cohort. Metabolic syndrome was defined as having at least three of the following: elevated waist circumference, triglycerides, blood pressure, or glycated haemoglobin, or reduced HDL cholesterol. Incident all-cause dementia was ascertained through hospital inpatient, death, and mental health-care records. In full-cohort analyses, we studied 20 150 adults without dementia aged 50-79 years who attended baseline assessments. Cox proportional hazards models were used to estimate the association between metabolic syndrome and dementia in the full sample, and in mid-life (50-59 years and 60-69 years) and late-life (70-79 years). To assess duration of metabolic syndrome, group-based trajectory analysis was performed on 12 756 participants who attended at least two health assessments over 20 years.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Findings: &lt;/strong&gt;The mean age of participants was 62·6 years (SD 7·5), and 10 857 (54%) were female. Over 25 years of follow-up (mean 18·8 years [SD 6·3]), 2653 (13%) participants developed dementia. In the full cohort, metabolic syndrome was associated with an increased risk of dementia (hazard ratio 1·11, 95% CI 1·01-1·21). In age-specific analyses, the association was similar for participants in late mid-life (age 60-69 years: 1·21, 1·05-1·39) and, although non-significant, in early mid-life (age 50-59 years: 1·12, 0·87-1·43), but attenuated for participants in late-life (age 70-79 years: 0·96, 0·81-1·14). A linear trend was observed between the number of metabolic syndrome components and dementia risk in those aged 60-69 years (p&lt;sub&gt;trend&lt;/sub&gt;=0·0040), but not in other age groups. In trajectory analysis, a prolonged duration of metabolic syndrome was associated with a significantly increased risk of developing dementia (1·26, 1·13-1·40) when compared to those with consistently low metabolic syndrome. No association was found for increasing metabolic syndrome (1·01, 0·88-1·17).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Interpretation: &lt;/strong&gt;These findings provide insights into how certain age windows and time periods might differentially affect dementia risk in the context of metabolic syndrome, and highlight the importance of considering age and duration of exposure to metabolic syndrome when devising dementia prevention strategies.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Funding: &lt;/strong&gt;Canadian Institutes of Health Research-Institute of Aging, Oxford Population Health, and the Nicolaus","PeriodicalId":34394,"journal":{"name":"Lancet Healthy Longevity","volume":" ","pages":"100652"},"PeriodicalIF":13.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highlights of the SIOG Annual Conference 2024.","authors":"Sophie Raeder","doi":"10.1016/j.lanhl.2024.100667","DOIUrl":"https://doi.org/10.1016/j.lanhl.2024.100667","url":null,"abstract":"","PeriodicalId":34394,"journal":{"name":"Lancet Healthy Longevity","volume":" ","pages":"100667"},"PeriodicalIF":13.4,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of oral health on functional disability and mortality in older adults in Japan: a cohort study","authors":"Takafumi Abe PhD ,&nbsp;Kazumichi Tominaga DDS ,&nbsp;Hisaaki Saito DDS ,&nbsp;Jun Shimizu PhD ,&nbsp;Norikuni Maeda DDS ,&nbsp;Ryouji Matsuura PhD ,&nbsp;Yukio Inoue DDS ,&nbsp;Yuichi Ando PhD ,&nbsp;Yuhei Matsuda PhD ,&nbsp;Takahiro Kanno PhD ,&nbsp;Shozo Yano PhD ,&nbsp;Minoru Isomura PhD","doi":"10.1016/j.lanhl.2024.08.005","DOIUrl":"10.1016/j.lanhl.2024.08.005","url":null,"abstract":"<div><h3>Background</h3><div>Oral health has previously shown associations with functional disability and mortality. We aimed to explore the associations of various aspects of oral health status with functional disability and mortality using survival analysis, as well as the relative magnitudes of the impact of these aspects on outcomes.</div></div><div><h3>Methods</h3><div>We obtained data for individuals aged 75 years and older in Shimane, Japan, who had at least one oral health check-up between April 1, 2016, and March 31, 2022 under Japan’s long-life medical care system insurance system. Those with missing data or with functional disability at baseline were excluded. 13 aspects of oral health status were assessed by dentists or dental hygienists as part of the check-up (using protocols provided by the Japan Dental Association and the Japanese Ministry of Health, Labour and Welfare): number of remaining teeth, subjective masticatory performance, objective masticatory performance, periodontal tissue status, functional dysphagia, tongue mobility, articulation, oral hygiene, number of decayed teeth, inadaptation of dentures of the upper jaw and lower jaw (considered separately), oral mucosal disease, and dry mouth. Multivariate Cox proportional hazards models were used to analyse the associations between each aspect of oral health and functional disability and mortality, with fully adjusted models adjusting for sex, age, BMI, medical history, or a propensity score derived from these covariates. Population-attributable fractions (PAFs) were calculated to assess the differential impacts of these oral health status aspects on outcome occurrence.</div></div><div><h3>Findings</h3><div>Of the 24 619 individuals who had an oral health check-up during the study period, 21 881 individuals were included in the analysis of functional disability (9175 [41·93%] men, 12 706 [58·07%] women, mean age 78·31 years [SD 2·88], mean follow-up 41·43 months [20·80]), and 22 747 individuals in the analysis of mortality (9722 [42·74%] men, 13 025 [57·26%] women, mean age 78·34 years [2·89], mean follow-up 42·63 months [20·58]). All 13 aspects of oral health status showed significant associations with the occurrence of mortality, while functional disability was associated with 11 aspects (excluding oral mucosal disease and dry mouth) in the fully adjusted model. Based on PAFs, of all oral health aspects assessed, objective masticatory performance had the greatest impact on both functional disability (PAF 23·10% [95% CI 20·42–25·69] for the lowest and 10·62% [8·18–12·99] for the second-lowest quartile of performance) and mortality (16·47% [13·44–19·40] and 8·90% [5·87–11·82]).</div></div><div><h3>Interpretation</h3><div>Various aspects of oral health are associated with mortality and functional disability. Maintaining good oral health in older adults might help to reduce these outcomes.</div></div><div><h3>Funding</h3><div>None.</div></div>","PeriodicalId":34394,"journal":{"name":"Lancet Healthy Longevity","volume":"5 11","pages":"Article 100636"},"PeriodicalIF":13.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating immunisation into a global strategy for healthy ageing","authors":"Anna Odone ,&nbsp;Giacomo Pietro Vigezzi","doi":"10.1016/j.lanhl.2024.100654","DOIUrl":"10.1016/j.lanhl.2024.100654","url":null,"abstract":"","PeriodicalId":34394,"journal":{"name":"Lancet Healthy Longevity","volume":"5 11","pages":"Article 100654"},"PeriodicalIF":13.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caring for our invisible older carers","authors":"The Lancet Healthy Longevity","doi":"10.1016/j.lanhl.2024.100662","DOIUrl":"10.1016/j.lanhl.2024.100662","url":null,"abstract":"","PeriodicalId":34394,"journal":{"name":"Lancet Healthy Longevity","volume":"5 11","pages":"Article 100662"},"PeriodicalIF":13.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating complex care for older women with HIV: role of geriatrician support","authors":"Luxey Sirisegaram ,&nbsp;Kristina Marie Kokorelias ,&nbsp;Alice Zhabokritsky ,&nbsp;Sharon Walmsley","doi":"10.1016/j.lanhl.2024.100649","DOIUrl":"10.1016/j.lanhl.2024.100649","url":null,"abstract":"","PeriodicalId":34394,"journal":{"name":"Lancet Healthy Longevity","volume":"5 11","pages":"Article 100649"},"PeriodicalIF":13.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}